CN107510806A

CN107510806A - It is a kind of to be used to treat decoction medicine of periodontitis and preparation method thereof

Info

Publication number: CN107510806A
Application number: CN201710918461.0A
Authority: CN
Inventors: 夏瑜
Original assignee: Sichuan Jintang Haina Biomedical Technology Institute
Current assignee: Sichuan Jintang Haina Biomedical Technology Institute
Priority date: 2017-09-30
Filing date: 2017-09-30
Publication date: 2017-12-26

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to which a kind of decoction medicine for being used to treat periodontitis provided according to the understanding mechanism of Chinese traditional treatment periodontitis, each component and its mass parts ratio of the medicine are as follows：10~25g of fructus gardeniae, 10~38g of prepared rhizome of rehmannia, 10~25g of herba fibraureae recisae, 3~8g of the fruit of Chinese magnoliavine, 10~18g of stauntonvine, 10~38g of radix rehmanniae recen, 6~15g of quassia, 10~35g of the Radix Astragali, 5~10g of Radix zanthoxyli, 15~35g of acute turpinia leaf, 8~16g of Radix Angelicae Sinensis, 6~15g of the radix paeoniae rubrathe, 6~15g of lophatherum gracile, 8~16g of peach kernel, 2~6g of milfoil, 3~15g of radix glycyrrhizae；Medicine provided by the invention is a good Chinese prescription.

Description

It is a kind of to be used to treat decoction medicine of periodontitis and preparation method thereof

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of decoction medicine for being used to treat periodontitis, particularly supply The field of the decoction medicine that patients with periodontitis uses and preparation method thereof.

Background technology

Motherland's medical science thinks：Periodontitis is mainly the chronic inflammation of the Periodontal Supporting Tissue as caused by local factor.Morbidity Age is later more common with 35 years old.As oulitis fails to treat in time, inflammation can be diffused into parodontium, alveolus from gum to deep layer Bone and cementum and develop into periodontitis.It is tighter when having symptom because early stage is how easily ignored without obvious subjective symptoms Weight, or even tooth can not be retained.

Clinical manifestation：

Early symptom is less obvious, and patient often only has the performance of Secondary cases bleeding gums or halitosis, similar to symptoms of gingivitis.Check Shi Kejian gums edge, the swelling of gum nipple and attached gingiva, matter are soft, and in peony or kermesinus, easy bleeding is examined in spy.With inflammation , there are following symptoms in further diffusion：

A. periodontal bag formation

Due to the extension of inflammation, parodontium is destroyed, and alveolar bone gradually absorbs, and gum separates with root of the tooth, gingival sulcus is deepened and shape Into oral pocket.Depth of pocket can be surveyed with probe.

B. periodontal pyorrhea

Oral pocket wall has ulcer and inflammatory granulation tissue to be formed, and has purulent secretion to retain in bag, therefore flicking gum, it is seen that overflows Purulence.And often there is halitosis.

C. tooth mobility

Because periodontium is destroyed, when particularly absorption of alveolar bone aggravates, support tooth strength deficiency, occur tooth mobility, Phenomena such as displacement.Now patient, which often feels, is engaged powerless, dull pain, and bleeding gums and halitosis aggravate.

When Abwehrkraft des Koepers reduces, oral pocket sepage inadequate drainage when, periodontal abscess can be formed, it is late to be that periodontitis develops into Phase, there is a common concomitant symptom of deep oral pocket.Now gum is in oval projection, rubescent swelling, surface-brightening；Tooth The increase of loose compact degree, kowtows pain；Patient acutely jumps pain with local.Meanwhile patient can have body temperature to raise, general malaise, under jaw The symptoms such as enlargement of lymph nodes, tenderness.

So, just how to find a kind of Chinese medicine composition that can effectively treat periodontitis, be those skilled in the art urgently Solve the problems, such as.

The content of the invention

With the continuous development of China's traditional Chinese medicine, in treatment periodontitis, people gradually appreciate Chinese traditional treatment The advantages of periodontitis, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, for existing western medical treatment tooth Zhou Yan present situation, the purpose of the present invention is to be to provide a kind of decoction medicine for being used to treat periodontitis, to solve periodontitis The problem of person gets well early.The medicine be using common Chinese medicine as raw material, by selecting rational medicine and mass parts ratio, Above-mentioned periodontitis can effectively be treated.

To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：There is provided a kind of for treating periodontitis Decoction medicine and preparation method thereof, it is characterised in that each component and its mass parts of the medicine are than as follows：

10~25g of fructus gardeniae, 10~38g of prepared rhizome of rehmannia, 10~25g of herba fibraureae recisae, 3~8g of the fruit of Chinese magnoliavine, 10~18g of stauntonvine, radix rehmanniae recen 10~38g, 6~15g of quassia, 10~35g of the Radix Astragali, 5~10g of Radix zanthoxyli, 15~35g of acute turpinia leaf, 8~16g of Radix Angelicae Sinensis, the radix paeoniae rubrathe 6 ~15g, 6~15g of lophatherum gracile, 8~16g of peach kernel, 2~6g of milfoil, 3~15g of radix glycyrrhizae.

It is a kind of to be used to treat decoction medicine of periodontitis and preparation method thereof, it is characterised in that each group of the medicine Divide and its mass parts are than as follows：

12~22g of fructus gardeniae, 12~35g of prepared rhizome of rehmannia, 12~22g of herba fibraureae recisae, 4~7g of the fruit of Chinese magnoliavine, 12~16g of stauntonvine, radix rehmanniae recen 12~35g, 7~13g of quassia, 12~31g of the Radix Astragali, 6~9g of Radix zanthoxyli, 18~31g of acute turpinia leaf, 9~14g of Radix Angelicae Sinensis, the radix paeoniae rubrathe 7~ 13g, 7~13g of lophatherum gracile, 9~14g of peach kernel, 3~5g of milfoil, 5~13g of radix glycyrrhizae.

It is a kind of to be used to treat decoction medicine of periodontitis and preparation method thereof, it is characterised in that " preferred plan " The each component and its mass parts of medicine are than as follows：

Fructus gardeniae 20g, prepared rhizome of rehmannia 31g, herba fibraureae recisae 20g, fruit of Chinese magnoliavine 6g, stauntonvine 14g, radix rehmanniae recen 31g, quassia 12g, Radix Astragali 28g, Radix zanthoxyli 8g, acute turpinia leaf 28g, Radix Angelicae Sinensis 12g, radix paeoniae rubrathe 12g, lophatherum gracile 12g, peach kernel 13g, milfoil 4g, radix glycyrrhizae 12g.

It is a kind of to be used to treat decoction medicine of periodontitis and preparation method thereof, it is characterised in that methods described includes as follows Step is prepared：

A, after above-mentioned raw materials Chinese medicine being picked into impurity and dust, it is respectively crushed into coarse according to mass parts ratio and decocts a drug wrapped；

B, 1. the raw material Chinese medicine wrapped is put into cold boiling water and soaks 35min, then again by soaked medicine and soak medicine Clarified solution be put into the lump in marmite, injected medicine 66mm cold boiling water carry out first time high heat decoction, wait decoct arrive 15min When, turn slow fire and boil 38 min, leaching decoction；2. the tepor boiling water that medicine 60mm was re-injected in the dregs of a decoction carries out second of intense fire Decoct, when 10min is arrived in decoction, turn slow fire and boil 32 min, leaching decoction；It is condensed into 3. decoction twice is mixed in 50% Decoction 360ml（Milliliter）, seal standby.

It is a kind of to be used to treat decoction medicine of periodontitis and preparation method thereof, it is characterised in that the instructions of taking is：Will The herb liquid prepared was taken with one day, one portion per day, morning and evening sub-service, dosage 180ml/ times, takes advantage of and warmly takes.One week was 1 The course for the treatment of, it is discontinued two days between three courses for the treatment of.1~4 course for the treatment of of medication, toothache disappear, and disease obtains recovery from illness.

Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：

Fructus gardeniae, nature and flavor：Hardship, tremble with fear, there is the effect of heat-clearing, purging intense heat, cool blood, for treating pyreticosis restlessness of asrhenia type and insomnia, jaundice, leaching Disease, quench one's thirst, hot eyes, pharyngalgia, haematemesis, bleeding from five sense organs or subcutaneous tissue, bloody flux, hematuria, pathopyretic ulcer, sprain swelling and pain；

Prepared rhizome of rehmannia, nature and flavor：Sweet, tepor, there is the effect of nourishing yin and supplementing blood, beneficial to spirit and marrow, for treating the deficiency of liver-yin and kidney-yin, waist and knee acid Soft, osteopyrexia and fever, night sweat seminal emission, Heat Diabetes, blood deficiency chlorosis, palpitation and severe palpitation, irregular menstruation, metrostaxis, dizziness, tinnitus, Poliosis；

Herba fibraureae recisae, nature and flavor：Sweetness and bitterness, tremble with fear, it is poisonous, there is the effect of heat-clearing, removing toxic substances, diuresis, defaecation, for Therapeutic diet poisoning, heat Strongly fragrant constipation, dysentery, catarrhal jaundice, sore carbuncle, cute conjunctivitis, abscess of throat；

The fruit of Chinese magnoliavine, nature and flavor：It is sour, sweet, warm, there is the effect of restraining astringent or styptic treatment for spontaneous sweating, nourishing generate fluid, kidney calming, for treating chronic diarrhea not Only, chronic cough and dyspnea of deficiency type, palpitaition, insomnia, dreaminess, spontaneous perspiration, night sweat, injury thirst, quench one's thirst, pass out semen, involuntary emission；

Stauntonvine, nature and flavor：It is sweet, warm-natured, there is the effect of wind-dispelling and network, promoting blood circulation and stopping pain, inducing diuresis to remove edema, for treating rheumatism numbness Bitterly, the diseases such as the pain of stomach, enteron aisle and biliary diseases, trigeminal neuralgia, traumatic injury, dysmenorrhoea, difficult urination, oedema；

Radix rehmanniae recen, nature and flavor：It is sweet, bitter, cold in nature, there is the effect of heat-clearing, cool blood, enter ying blood, high fever for treating warm heat disease heat Coma, dry tongue are deep red；

Quassia, nature and flavor：It is bitter, cold, it is slightly poisonous, there is the effect of clearing heat and detoxicating, removing dampness and destroying parasites, for treat the infection of the upper respiratory tract, Pneumonia, acute gastroenteritis, dysentery, infection of biliary tract, boil, mange, eczema, scald, venomous snake bite；

The Radix Astragali, nature and flavor：It is sweet, warm, there is the effect of invigorating qi for strengthening superficies, inducing diuresis to remove edema, pus draining and toxin expelling, expelling pus and promoting granulation, myogenic, for controlling Treat treatment deficiency of vital energy weak, anorexia and loose stool, the sinking of qi of middle-jiao, rush down prolapse of the anus for a long time, uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy oedema, ulcer is difficult to burst, long Burst do not hold back, flaccidity of limbs due to deficiency of blood is yellow, Heat Diabetes, chronic rephrilis protinuria, diabetes；

Radix zanthoxyli, nature and flavor：It is bitter, pungent, flat, it is slightly poisonous, there is the effect of promoting qi circulation and relieving pain, promoting blood circulation and removing blood stasis, dispelling wind and removing obstruction in the meridians, for treating Traumatic injury, arthralgia pain due to rheumatism, stomachache, toothache, venomous snake bite caused by qi depression to blood stasis, the burning hot wound of soup is controlled outside；

Acute turpinia leaf, nature and flavor：It is bitter, cold, there is the effect of clearing heat and detoxicating, reducing pharyngeal swelling, promoting blood circulation and stopping pain, for treating acute tonsillitis larynx Numbness, abscess of throat, sore swollen toxin, the pain of injury caused by falling and tumbling；

Radix Angelicae Sinensis, nature and flavor：It is sweet, pungent, slight bitter, warm-natured, there is the effect of benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize laxation, for treating Irregular menstruation, Amenorrhea stomachache, Disorder lumps in the abdomen knot are poly-, uterine bleeding, headache due to deficiency of blood, dizziness, Impotence numbness, intestines are dry and shit is difficult, weight after dysentery characterized by blood in the stool, ulcer sore Surreptitiously, injury from falling down；

The radix paeoniae rubrathe, nature and flavor：It is bitter, be slightly cold, there is the effect of clearing heat and cooling blood, promoting blood circulation, for treat febrile virulent maculae, hematemesis and epistaxis, Discharging fresh blood stool, red eye, swell pain, carbuncle swells sore, amenorrhoea, dysmenorrhoea, collapse band stranguria with turbid discharge, the stagnant hypochondriac pain of the stasis of blood, hernia lump in the abdomen accumulation, injury from falling down；

Lophatherum gracile, nature and flavor：It is sweet, light, cold, there is the effect of clearing heat and relieving fidgetness, diuresis, for treating pyreticosis polydipsia, hot urination leaching Bitterly, aphthae；

Peach kernel, nature and flavor：It is bitter sweet, flat, there is the effect of blood-breaking row stasis of blood, moisturize laxation, for treating Amenorrhea, Disorder lumps in the abdomen, pyreticosis stores blood, The dry constipation of wandering arthritis, malaria, traumatic injury, blood stasis and swelling pain, blood；

Milfoil, nature and flavor：It is pungent, bitter, flat, it is slightly poisonous, have removing toxicity for detumescence, hemostasis, analgesic the effect of, for treat rheumatalgia pain, Venomous snake bite, carbuncle furuncle poison, traumatic injury, traumatism and bleeding are controlled in toothache, Amenorrhea stomachache, stomachache, enteritis, dysentery, external application；

Radix glycyrrhizae, nature and flavor：It is sweet, flat, have invigorating middle warmer and replenishing QI, relieving spasm to stop pain, moisten the lung and relieve the cough, purging intense heat and detonicating, coordinating the drug actions of a prescription the effect of, use Swollen in treatment burnout deficiency of food, the thin face Huang of flesh, palpitation, stomachache loose stool, four limbs contraction, hysteria, cough and asthma, throat Bitterly, ulcerative carbuncle swelling and pain, infant fetal toxin and medicine, food poisoning.

Medicine of the present invention is the principle based on Chinese traditional treatment periodontitis, from the pathomechanism according to periodontitis and pharmacological action Think：With regard to periodontitis, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, has good treatment to above-mentioned disease Effect.

Embodiment

A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of above-mentioned periodontitis, the medicine prepared using the formula Thing good drug efficacy, it is quick, it is a Chinese prescription treated both principal and secondary aspect of disease, is particularly suitable for Clinical practice.With reference to the tool of the present invention Body embodiment is described in further detail：

Embodiment 1：

A kind of decoction medicine for being used to treat periodontitis, it is characterised in that each component and its mass parts of the medicine are such as Shown in lower：

Embodiment 2：

Fructus gardeniae 22g, prepared rhizome of rehmannia 35g, herba fibraureae recisae 22g, fruit of Chinese magnoliavine 7g, stauntonvine 16g, radix rehmanniae recen 35g, quassia 13g, Radix Astragali 31g, Radix zanthoxyli 9g, acute turpinia leaf 31g, Radix Angelicae Sinensis 14g, radix paeoniae rubrathe 13g, lophatherum gracile 13g, peach kernel 14g, milfoil 5g, radix glycyrrhizae 13g.

Embodiment 3：

Fructus gardeniae 25g, prepared rhizome of rehmannia 38g, herba fibraureae recisae 25g, fruit of Chinese magnoliavine 8g, stauntonvine 18g, radix rehmanniae recen 38g, quassia 15g, Radix Astragali 35g, Radix zanthoxyli 10g, acute turpinia leaf 35g, Radix Angelicae Sinensis 16g, radix paeoniae rubrathe 15g, lophatherum gracile 15g, peach kernel 16g, milfoil 6g, radix glycyrrhizae 15g.

Model case

Through clinical conditions patients with periodontitis totally 1100, the age is 700 of more than 42 years old, only 400 for 42 years old with Under.1020 to be fully recovered in 1100 patients, effective 80, total effective rate is up to 100%.

Claims

A kind of 1. decoction medicine for being used to treat periodontitis, it is characterised in that each component and its mass parts ratio of the medicine It is as follows：

10~25g of fructus gardeniae, 10~38g of prepared rhizome of rehmannia, 10~25g of herba fibraureae recisae, 3~8g of the fruit of Chinese magnoliavine, 10~18g of stauntonvine, radix rehmanniae recen 10~38g, 6~15g of quassia, 10~35g of the Radix Astragali, 5~10g of Radix zanthoxyli, 15~35g of acute turpinia leaf, 8~16g of Radix Angelicae Sinensis, the radix paeoniae rubrathe 6 ~15g, 6~15g of lophatherum gracile, 8~16g of peach kernel, 2~6g of milfoil, 3~15g of radix glycyrrhizae.
2. the decoction medicine according to claim 1 for being used to treat periodontitis, it is characterised in that each group of the medicine Divide and its mass parts are than as follows：

12~22g of fructus gardeniae, 12~35g of prepared rhizome of rehmannia, 12~22g of herba fibraureae recisae, 4~7g of the fruit of Chinese magnoliavine, 12~16g of stauntonvine, radix rehmanniae recen 12~35g, 7~13g of quassia, 12~31g of the Radix Astragali, 6~9g of Radix zanthoxyli, 18~31g of acute turpinia leaf, 9~14g of Radix Angelicae Sinensis, the radix paeoniae rubrathe 7~ 13g, 7~13g of lophatherum gracile, 9~14g of peach kernel, 3~5g of milfoil, 5~13g of radix glycyrrhizae.
3. being used for according to claim 1 to 2 treats the decoction medicine of periodontitis, it is characterised in that the medicine it is each Individual component and its mass parts are than as follows：

Fructus gardeniae 20g, prepared rhizome of rehmannia 31g, herba fibraureae recisae 20g, fruit of Chinese magnoliavine 6g, stauntonvine 14g, radix rehmanniae recen 31g, quassia 12g, Radix Astragali 28g, Radix zanthoxyli 8g, acute turpinia leaf 28g, Radix Angelicae Sinensis 12g, radix paeoniae rubrathe 12g, lophatherum gracile 12g, peach kernel 13g, milfoil 4g, radix glycyrrhizae 12g.