CN107469011A - A kind of capsule medicine for treating pelvic infecton and preparation method thereof - Google Patents

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to which a kind of capsule medicine for treating pelvic infecton provided according to the understanding mechanism of Chinese traditional treatment pelvic infecton, each component and its mass parts ratio of the medicine are as follows：60~160g of Radix Angelicae Sinensis, 30~100g of spina gleditsiae, 40~120g of the radix paeoniae rubrathe, 50~120g of Rhizoma Sparganii, 30~120g of curcuma zedoary, 90~160g of Sargent gloryvine, 50~90g of Fructus meliae toosendan, rhizoma cyperi (vinegar system) 50~100g, 80~160g of corydalis tuber, 90~160g of giant knotweed, 30~100g of rhizoma atractylodis, 150~360g of Chinese yam, 30~150g of golden cypress, 100~350g of dandelion, 250~560g of smilax, 250~560g of waras, 500~900g of chinaroot greenbrier, 90~350g of motherwort, medicine provided by the invention are a good Chinese prescriptions.

Description

A kind of capsule medicine for treating pelvic infecton and preparation method thereof

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of capsule medicine for treating pelvic infecton, particularly for basin The field of the capsule medicine that chamber inflammation patient uses and preparation method thereof.

Background technology

Doctor thinks：Pelvic infecton is pelvic inflammation, refers to the connective tissue and basin of female pelvic cavity reproductive organs, periuterine The inflammation of chamber peritonaeum.Chronic pelvic inflammation is often that acute stages treated is not delayed thoroughly, its disease time length, and the state of an illness is stupider Gu.Bacterium retrograde infection, pelvic cavity is reached by uterus, fallopian tubal.But in actual life, not all women can Pelvic infecton is suffered from, morbidity is minority.Because female reproductive system has natural defense function, under normal circumstances, energy Resist the invasion of bacterium, only when the resistance of body declines, or due to other reasonses make the natural defense function of women by During destruction, it can just cause the generation of pelvic infecton.

Clinical manifestation：

Pelvic inflammation has acute and chronic two class：

A. acute pelvic inflammation

Its symptom is that hypogastralgia, heating, vaginal fluid increase, and is suffered from abdominal pain as continuation, activity or sexual intercourse postemphasis.If the state of an illness is tight Weight can have shiver with cold, high fever, headache, poor appetite.Menstrual period, hair patient may occur in which menorrhagia, and menostaxis, if pelvic infecton bag Wrap up in and to form pelvic abscess and can cause local compression symptom, compressing bladder may occur in which frequent micturition, odynuria, dysuria；Oppressing rectum can There is tenesmus rectum symptom of Denging.Further development can cause general peritonitis, septicemia, infectivity to be stopped to acute pelvitis of pelvic cavity Gram, severe patient can threat to life.

B. chronic pelvic inflammation

It is due to that acute pelvitis of pelvic cavity fails thoroughly to treat or patient's constitution is poor, caused by course of disease delay, the disease of chronic pelvic inflammation Shape is lower abdomen falling inflation, and pain and lumbosacral region are ached, and is often aggravated after tired, sexual intercourse and before and after menstruation.Next to that menoxenia, Irregular menses.Some women may occur in which the neurasthenia symptoms such as the uncomfortable, insomnia of lassitude, the whole body when course of disease is long.Often pass through It is not cured long, recurrent exerbation, causes infertile, tubal pregnancy, have a strong impact on the health of women.

So, just how to find a kind of Chinese medicine composition that can effectively treat pelvic infecton, be those skilled in the art urgently Solve the problems, such as.

The content of the invention

With the continuous development of China's traditional Chinese medicine, in treatment pelvic infecton, people gradually appreciate Chinese traditional treatment The advantages of pelvic infecton, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, for existing western medical treatment basin The scorching present situation of chamber, the purpose of the present invention is to be to provide a kind of capsule medicine for treating pelvic infecton, to solve Patients with Pelvic Inflammatory Disease The problem of getting well early.The medicine be using common Chinese medicine as raw material, by selecting rational medicine and its mass parts ratio, Above-mentioned pelvic infecton one can be effectively treated to demonstrate,prove.

To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：A kind of glue for treating pelvic infecton is provided Wafer medicine and preparation method thereof, it is characterised in that each component and its mass parts of the medicine are than as follows：

60~160g of Radix Angelicae Sinensis, 30~100g of spina gleditsiae, 40~120g of the radix paeoniae rubrathe, 50~120g of Rhizoma Sparganii, 30~120g of curcuma zedoary, Sargent gloryvine 90 ~160g, 50~90g of Fructus meliae toosendan, rhizoma cyperi (vinegar system) 50~100g, 80~160g of corydalis tuber, 90~160g of giant knotweed, rhizoma atractylodis 30~ 100g, 150~360g of Chinese yam, 30~150g of golden cypress, 100~350g of dandelion, 250~560g of smilax, waras 250~ 560g, 500~900g of chinaroot greenbrier, 90~350g of motherwort, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.

A kind of capsule medicine for treating pelvic infecton and preparation method thereof, it is characterised in that each component of the medicine And its mass parts are than as follows：

70~130g of Radix Angelicae Sinensis, 38~90g of spina gleditsiae, 48~105g of the radix paeoniae rubrathe, 58~105g of Rhizoma Sparganii, 38~105g of curcuma zedoary, Sargent gloryvine 100 ~130g, 58~80g of Fructus meliae toosendan, rhizoma cyperi (vinegar system) 58~90g, 90~130g of corydalis tuber, 100~130g of giant knotweed, rhizoma atractylodis 38~ 90g, 180~320g of Chinese yam, 38~130g of golden cypress, 115~310g of dandelion, 280~500g of smilax, waras 280~ 500g, 580~750g of chinaroot greenbrier, 100~310g of motherwort, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.

A kind of capsule medicine for treating pelvic infecton and preparation method thereof, it is characterised in that each component of the medicine And its mass parts are than as follows：

Radix Angelicae Sinensis 115g, spina gleditsiae 80g, radix paeoniae rubrathe 95g, Rhizoma Sparganii 95g, curcuma zedoary 95g, Sargent gloryvine 115g, Fructus meliae toosendan 70g, rhizoma cyperi (vinegar system) It is 80g, corydalis tuber 115g, giant knotweed 116g, rhizoma atractylodis 80g, Chinese yam 260g, golden cypress 115g, dandelion 280g, smilax 430g, very heavy Pull out 430g, chinaroot greenbrier 650g, motherwort 280g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.

A kind of capsule medicine for treating pelvic infecton and preparation method thereof, it is characterised in that methods described includes following step Suddenly it is prepared：

A, after above-mentioned raw materials Chinese medicine being picked into impurity and dust, it is ground into according to mass parts than altogether（30~50 mesh）Graininess bag Decoct；

B, 1. the raw material Chinese medicine wrapped is put into cold boiling water and soaks 60min, then soaked medicine is put into marmite again, The cold boiling water for adding 7~8 times of raw material Chinese medicine weight carries out first time high heat decoction, when 18min is arrived in decoction, turns slow fire and boils 120min, leaching decoction；2. the cold boiling water for adding 6~7 times of raw material Chinese medicine weight in the dregs of a decoction again is fried by intense fire for the second time Boil, when 15min is arrived in decoction, turn slow fire and boil 110min, leaching decoction；3. decoction mixing twice is condensed into relative density is 1.08 clear cream, then dry, grind and sterilize after it is standby；

C, the method for 1. preparing Chinese medicine capsules according to tradition, after smalls sieving ground in B, appropriate micro mist silicon is added Glue, microcrystalline cellulose and starch are well mixed, and are then prepared into capsule（Total length is 23.3mm after its capsule is sealed, medicinal powder Capacity 0.4~0.5g/ grains）, 2. then polish, sterilize, sealed packaging.

A kind of capsule medicine for treating pelvic infecton and preparation method thereof, it is characterised in that the instructions of taking is：Will system The capsule medicine got ready is three times a day to take, and once a dose in the morning, afternoon and evening, dosage 3g（6）/ time, warm water delivery service, 15 It is a course for the treatment of, while can combine western medicine, and 3~7 courses for the treatment of of taking medicine, symptom disappears, and disease obtains recovery from illness.

Each raw material Chinese medicine in prescription of the present invention has detailed in Chinese Pharmacopoeia, Chinese dictionary and its China's book on Chinese herbal medicine Record.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：

Radix Angelicae Sinensis, nature and flavor：It is sweet, pungent, bitter, warm-natured, there is the effect of enriching blood, invigorate blood circulation, menstruction regulating and pain relieving, moisturize laxation, for treating The all cards of the deficiency of blood, irregular menstruation, Amenorrhea, dysmenorrhoea, Disorder lumps in the abdomen knot are poly-, uterine bleeding, asthenia cold abdominalgia, Impotence numbness, numbness, intestines are dry and shit is difficult, red Weight, ulcer sores, injury from falling down after dysentery；

Spina gleditsiae, nature and flavor：It is pungent, warm, have detumescence eliminating toxic, apocenosis, desinsection the effect of, for treat ulcer from the beginning of or purulence into not Burst, control mange leprosy outside；

The radix paeoniae rubrathe, nature and flavor：It is bitter, be slightly cold, there is the effect of clearing heat and cooling blood, promoting blood circulation, for treat febrile virulent maculae, hematemesis and epistaxis, Discharging fresh blood stool, red eye, swell pain, carbuncle swells sore, amenorrhoea, dysmenorrhoea, collapse band stranguria with turbid discharge, the stagnant hypochondriac pain of the stasis of blood, hernia lump in the abdomen accumulation, injury from falling down；

Rhizoma Sparganii, nature and flavor：It is acrid flavour, puckery, cool, there is the effect of blood-breaking, Xiao Ji Zhi Tong, for treating the stagnant warp of abdominal mass lump in the abdomen, the stasis of blood Close, dysmenorrhoea, dyspepsia distending pain, fall year the pain of injury；

Curcuma zedoary, nature and flavor：Acrid flavour；It is bitter；It is warm-natured, there is the effect of promoting the circulation of qi blood-breaking, Xiao Ji Zhi Tong, vim and vigour are pained, diet for treating Stagnant, abdominal distention, amenorrhea due to stagnation of blood, dysmenorrhoea, Disorder lump in the abdomen knurls lump in the abdomen, traumatic injury；

Sargent gloryvine, nature and flavor：It is bitter, flat, have it is clearing heat and detoxicating, promoting blood circulation, wind-dispelling the effect of, for treat abdominalgia with intestinal abscess, closed dysmenorrhea, Arthralgia pain due to rheumatism, tumbling and swelling；

Fructus meliae toosendan, nature and flavor：It is bitter, cold, it is slightly poisonous, there is the effect of relaxing liver promoting qi circulation and relieving pain, expelling parasite, it is swollen for treating chest side of body, gastral cavity abdomen Bitterly, colic, abdominal pain due to enterositosis；

Rhizoma cyperi (vinegar system), nature and flavor：Acrid flavour, be slightly cold, it is nontoxic, have regulating the flow of vital energy Xie Yu, menstruction regulating and pain relieving, it is antiabortive the effect of, for treating The distending pain in hypochondrium, breast swelling, hernia pain, irregular menstruation, epigastric abdominal fullness pain, belch acid regurgitation, evil of vomitting, dysmenorrhea, uterine bleeding Under band, the disease such as fetal irritability；

Corydalis tuber, nature and flavor：Acrid, bitter, warm, it is nontoxic, there is promoting blood circulation, dissipate the effect of stasis of blood, qi-regulating, analgesic, for treating trusted subordinate's waist and knee All pains, irregular menstruation, abdominal mass, metrorrhagia, postpartum anemic fainting, lochiorrhagia, traumatic injury；

Giant knotweed, nature and flavor：Slight bitter, be slightly cold, have expelling wind and removing dampness, scattered stasis pain, it is relieving cough and reducing sputum the effect of, for treating joint numbness Bitterly, jaundice with damp-heat pathogen, Amenorrhea, abdominal mass, scald, injury from falling down, carbuncle sore tumefacting virus, coughing with a lot of sputum；

Rhizoma atractylodis, nature and flavor：It is acrid flavour, hardship, warm-natured, there is the effect of drying damp and strengthening spleen, wind-damp dispelling, improving eyesight, for treating the spleen and stomach being stranded by dampness, tired Idle thermophilic sleeping, born of the same parents' ruffian abdominal distension, poor appetite, vomiting and diarrhea, phlegm and retained fluid, wet swollen, exterior syndrome press from both sides wet, head body weight pain, bi Zheng warm nature, podomere acid The diseases such as pain weighs, impotence folds in a garment, yctalopia；

Chinese yam, nature and flavor：It is sweet, flat, have tonifying spleen, support lung, reinforce the kidney, strengthening the essence the effect of, for treat splenasthenic diarrhea, deficiency of food edema, Deficiency syndrome of the lung cough and asthma, quench one's thirst, pass out semen, under band, kidney deficiency frequent micturition, external application control the diseases such as carbuncle swells, scrofula；

Golden cypress, nature and flavor：It is bitter, cold, there is the effect of heat-clearing and damp-drying drug, purging intense heat, except steaming, detoxification sore treatment, for treating damp-heat dysentery, Huang Subcutaneous ulcer, band under, heat gonorrhea, tinea pedis, impotence ward off, hectic fever due to yin labor heat, night sweat, seminal emission, sore swollen toxin, eczema itch, stir-baked CORTEX PHELLODENDRI with salt solution nourishing Yin and falling fire, For fire excess from yin deficiency, night sweat hectic fever due to yin；

Dandelion, nature and flavor：It is bitter, sweet, cold in nature, there is the effect of clearing heat and detoxicating, carbuncle that disappears dissipating bind, for treating acute mastitis, lung carbuncle, intestines Carbuncle, boil poisonous soreness, red eye, swell pain, cold, fever, cough, abscess of throat, stomach fire, enteritis, dysentery, hepatitis, courage frighten scorching, urinary tract sense Dye, snake bite and insect sting；

Smilax, nature and flavor：It is sweet light, flat, there is the effect of removing toxic substances, dehumidifying, sharp joint, for treating syphilis, stranguria with turbid discharge, muscles and bones contraction Bitterly, the disease such as tinea pedis, furunculosis, carbuncle swells, scrofula；

Waras, nature and flavor：Sweet, tepor, put down, there is the effect of wind-damp dispelling, strong waist and knee, for treating rheumatic arthritis, waist-leg Bitterly, lumbar muscle strain, leukorrhea, traumatic injury；

Chinaroot greenbrier, nature and flavor：It is sweet, sour, flat, there is expelling wind and removing dampness, removing toxicity for detumescence, root-like stock：Treat rheumatic arthritis, traumatic injury, Gastroenteritis, dysentery, indigestion, diabetes, chyluria, leukorrhea, cancer, leaf：The diseases such as carbuncle boils boils, scald are controlled in external application；

Motherwort, nature and flavor：It is bitter, pungent, be slightly cold, have promoting blood circulation for regulating menstruation, inducing diuresis to remove edema the effect of, for treat irregular menstruation, dysmenorrhoea, Amenorrhea, lochiorrhagia, oedema oliguria, acute nephritis edema.

Medicine of the present invention is the principle based on Chinese traditional treatment pelvic infecton, from the pathomechanism according to pelvic infecton and pharmacological action Think：With regard to pelvic infecton, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, has good effect to above-mentioned disease Fruit.

Embodiment

A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of above-mentioned pelvic infecton, the medicine prepared using the formula Thing good drug efficacy, it is quick, it is a good Chinese prescription, is particularly suitable for Clinical practice.With reference to the specific reality of the present invention The mode of applying is described in further detail：

Embodiment 1：

A kind of capsule medicine for treating pelvic infecton, it is characterised in that each component and its mass parts ratio of the medicine are as follows It is shown：

Radix Angelicae Sinensis 115g, spina gleditsiae 80g, radix paeoniae rubrathe 95g, Rhizoma Sparganii 95g, curcuma zedoary 95g, Sargent gloryvine 115g, Fructus meliae toosendan 70g, rhizoma cyperi (vinegar system) It is 80g, corydalis tuber 115g, giant knotweed 116g, rhizoma atractylodis 80g, Chinese yam 260g, golden cypress 115g, dandelion 280g, smilax 430g, very heavy Pull out 430g, chinaroot greenbrier 650g, motherwort 280g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.

Embodiment 2：

A kind of capsule medicine for treating pelvic infecton, it is characterised in that each component and its mass parts ratio of the medicine are as follows It is shown：

Radix Angelicae Sinensis 130g, spina gleditsiae 90g, radix paeoniae rubrathe 105g, Rhizoma Sparganii 105g, curcuma zedoary 105g, Sargent gloryvine 130g, Fructus meliae toosendan 80g, rhizoma cyperi (vinegar System) 90g, corydalis tuber 130g, giant knotweed 130g, rhizoma atractylodis 90g, Chinese yam 320g, golden cypress 130g, dandelion 310g, smilax 500g, Waras 500g, chinaroot greenbrier 750g, motherwort 310g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.

Embodiment 3：

A kind of capsule medicine for treating pelvic infecton, it is characterised in that each component and its mass parts ratio of the medicine are as follows It is shown：

Radix Angelicae Sinensis 160g, spina gleditsiae 100g, radix paeoniae rubrathe 120g, Rhizoma Sparganii 120g, curcuma zedoary 120g, Sargent gloryvine 160g, Fructus meliae toosendan 90g, rhizoma cyperi (vinegar System) 100g, corydalis tuber 160g, giant knotweed 160g, rhizoma atractylodis 100g, Chinese yam 360g, golden cypress 150g, dandelion 350g, smilax 560g, waras 560g, chinaroot greenbrier 900g, motherwort 350g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.

Model case

Through clinical conditions Patients with Pelvic Inflammatory Disease totally 1720, the age is 920 of more than 25 years old, only 800 for 25 years old with Under.880 to be fully recovered in 1720 patients, effective 788, invalid 52.Total effective rate is up to 97%.

Claims (3)

1. a kind of capsule medicine for treating pelvic infecton, it is characterised in that each component and its mass parts of the medicine are such as Shown in lower：

60~160g of Radix Angelicae Sinensis, 30~100g of spina gleditsiae, 40~120g of the radix paeoniae rubrathe, 50~120g of Rhizoma Sparganii, 30~120g of curcuma zedoary, Sargent gloryvine 90 ~160g, 50~90g of Fructus meliae toosendan, rhizoma cyperi (vinegar system) 50~100g, 80~160g of corydalis tuber, 90~160g of giant knotweed, rhizoma atractylodis 30~ 100g, 150~360g of Chinese yam, 30~150g of golden cypress, 100~350g of dandelion, 250~560g of smilax, waras 250~ 560g, 500~900g of chinaroot greenbrier, 90~350g of motherwort, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.

2. the capsule medicine for the treatment of pelvic infecton according to claim 1, it is characterised in that each component of the medicine And its mass parts are than as follows：

70~130g of Radix Angelicae Sinensis, 38~90g of spina gleditsiae, 48~105g of the radix paeoniae rubrathe, 58~105g of Rhizoma Sparganii, 38~105g of curcuma zedoary, Sargent gloryvine 100 ~130g, 58~80g of Fructus meliae toosendan, rhizoma cyperi (vinegar system) 58~90g, 90~130g of corydalis tuber, 100~130g of giant knotweed, rhizoma atractylodis 38~ 90g, 180~320g of Chinese yam, 38~130g of golden cypress, 115~310g of dandelion, 280~500g of smilax, waras 280~ 500g, 580~750g of chinaroot greenbrier, 100~310g of motherwort, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.

3. the capsule medicine of the treatment pelvic infecton according to claim 1 to 2, it is characterised in that the medicine it is each Component and its mass parts are than as follows：

Radix Angelicae Sinensis 115g, spina gleditsiae 80g, radix paeoniae rubrathe 95g, Rhizoma Sparganii 95g, curcuma zedoary 95g, Sargent gloryvine 115g, Fructus meliae toosendan 70g, rhizoma cyperi (vinegar system) It is 80g, corydalis tuber 115g, giant knotweed 116g, rhizoma atractylodis 80g, Chinese yam 260g, golden cypress 115g, dandelion 280g, smilax 430g, very heavy Pull out 430g, chinaroot greenbrier 650g, motherwort 280g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.