CN107468896A - 一种活血止痛散 - Google Patents

一种活血止痛散 Download PDF

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CN107468896A
CN107468896A CN201710640680.7A CN201710640680A CN107468896A CN 107468896 A CN107468896 A CN 107468896A CN 201710640680 A CN201710640680 A CN 201710640680A CN 107468896 A CN107468896 A CN 107468896A
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huoxue zhitong
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马昌豪
李洪芹
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Abstract

本发明公开了一种活血止痛散，包括以下原料：当归、独活、川断、羌活、红花、乳香、川牛膝、没药、苏木、桑枝、威灵仙、赤芍、川穹、秦艽、伸筋草、艾叶、鸡血藤、透骨草、降香、木瓜、黄芩、熟地、黄精、茶油、紫苏籽油、蜂蜜。本发明以多味中药为原料，科学配伍，各原料药之间协同作用，具有活血散瘀、消肿止痛的功效，疗程短，见效快、治疗率高，值得推广。

Description

一种活血止痛散
技术领域
本发明涉及中药技术领域，具体涉及一种活血止痛散。
背景技术
活血止痛药是日常生活中经常使用的药物，为理血剂，具有活血散瘀、消肿止痛的功效，可用于股骨头坏死、腰椎间盘突出、跌打损伤、骨折、骨质增生、风湿类风湿性关节炎、肢体麻木等恢复期治疗。目前市面上的活血止痛药物以外敷为主，疗程长、见效慢，且外敷会造成皮肤不适或影响美观等情况，效果不理想。
发明内容
为弥补现有技术的不足，本发明提供一种疗效显著的口服活血止痛散。
本发明是通过如下技术方案实现的：
一种活血止痛散，其特殊之处在于：包括以下重量份数的原料：当归10-20份、独活5-15份、川断10-15份、羌活10-20份、红花10-20份、乳香10-20份、川牛膝15-20份、没药10-15份、苏木10-20份、桑枝1-5份、威灵仙5-15份、赤芍10-15份、川穹10-15份、秦艽10-20份、伸筋草15-25份、艾叶15-25份、鸡血藤10-20份、透骨草10-20份、降香10-15份、木瓜10-20份、黄芩5-10份、熟地3-12份、黄精10-15份、茶油2-5份、紫苏籽油3-5份、蜂蜜10-15份。
本发明的优选方案是，一种活血止痛散，包括以下重量份数的原料：当归15份、独活10份、川断12份、羌活15份、红花15份、乳香15份、川牛膝18份、没药12份、苏木15份、桑枝3份、威灵仙10份、赤芍12份、川穹15份、秦艽15份、伸筋草20份、艾叶20份、鸡血藤15份、透骨草15份、降香12份、木瓜15份、黄芩8份、熟地10份、黄精12份、茶油3份、紫苏籽油3份、蜂蜜12份。
本发明的一种活血止痛散的制备方法，包括以下步骤：
（1）、将当归、独活、川断、羌活、乳香、没药、川穹、鸡血藤加水浸泡3-6h，然后在60-80℃的蒸汽下灭菌1-3min；
（2）、将步骤（1）灭菌后的原料加其重10-12倍的水磨浆，过100目筛得浆料；
（3）、将红花、威灵仙、赤芍、秦艽、伸筋草、艾叶、透骨草、降香洗净后烘干，在铁锅内加入茶油和紫苏籽油，然后加入蜂蜜，炒制10-15min，磨成粉面，过100目筛；
（4）、将川牛膝、苏木、桑枝、木瓜、黄芩、熟地、黄精一起洗净脱水，在80-100℃下杀菌烘干，磨成粉面，过100目筛；
（5）、将步骤（2）、（3）、（4）的物料混合，杀菌、乳化、均质，最后浓缩、喷雾干燥，自动包装封口得成品。
本发明的一种活血止痛散的制备方法，步骤（1）中蒸汽压力为1.5-3MPa。
本发明的一种活血止痛散的制备方法，步骤（5）中混合物料在120-150℃、真空度-0.03— -0.05 MPa下杀菌5-10s；乳化温度为60-80℃。
本发明中各原料药的作用如下：
当归：味甘、辛，性温。归肝、心、脾经。补血活血，调经止痛，润肠通便。用于血虚萎黄，眩晕心悸，月经不调，经闭痛经，虚寒腹痛，风湿痹痛，跌扑损伤，痈疽疮疡，肠燥便秘。酒当归活血通经。用于经闭痛经，风湿痹痛，跌扑损伤。
独活：味辛、苦，性微温。归肾、膀胱经。祛风除湿，痛痹止痛。用于风寒湿痹，要洗疼痛，少阴伏风头痛，风寒挟湿头痛。
川断：补肝肾，续筋骨，调血脉。主治腰背酸痛，足膝无力，胎漏，崩漏，带下，遗精，跌打损伤，金疮，痔漏，痈疽疮肿。
羌活：味辛、苦，性温。入膀胱、肾经。解表散寒，祛风胜湿，止痛。风寒感冒，风寒湿痹，项强筋急，骨节酸疼，风水浮肿，痈疽疮毒。
红花：味辛，性温。归心、肝经。活血通经，散瘀止痛。用于经闭，痛经，恶露不行，症瘕痞块，胸痹心痛，瘀滞腹痛，胸胁刺痛，跌扑损伤，疮疡肿痛。
乳香：味辛、苦，温。归心、肝、脾经。活血行气止痛，消肿生肌。用于胸痹心痛，胃脘疼痛，痛经经闭，产后瘀阻，症瘕腹痛，风湿痹痛，筋脉拘挛，跌打损伤，痈肿疮疡。
川牛膝：味甘、微苦，性平。归肝、肾经。逐瘀通经，通利关节，利尿通淋。用于经闭症瘕，胞衣不下，跌扑损伤，风湿痹痛，足痿筋挛，尿血血淋等证。
没药：味辛、苦，性平。归心、肝、脾经。散瘀定痛，消肿生肌。用于胸痹心痛，胃脘疼痛，痛经经闭，产后瘀阻，癥瘕腹痛，风湿痹痛，跌打损伤，痈肿疮疡等病症的治疗。
苏木：味甘、咸，平。归心、肝、脾经。活血祛瘀，消肿止痛。用于跌打损伤，骨折筋伤，瘀滞肿痛，经闭痛经，产后瘀阻，胸腹刺痛，痈疽肿痛。
桑枝：味微苦，性平。归肝经。有祛风湿，利关节的作用。用于风湿痹病，肩臂、关节酸痛麻木。
威灵仙：味辛、咸，性温。归膀胱经。有祛风湿，通经络的作用。用于风湿痹痛，肢体麻木，筋脉拘挛，屈伸不利。
赤芍：味苦，性微寒。归肝经。清热凉血，散瘀止痛。用于热人营血，温毒发斑，吐血衄血，目赤肿痛，肝郁胁痛，经闭痛经，瘾瘕腹痛，跌扑损伤，痈肿疮疡。
川穹：味辛，温。归肝、胆、心包经。活血行气，祛风止痛。用于月经不调，经闭痛经，症瘕腹痛，胸胁刺痛，跌扑肿痛，头痛，风湿痹痛。
秦艽：味辛、苦，性平。归胃、肝、胆经。有祛风湿，清湿热，止痹痛，退虚热的作用。用于风湿痹痛，中风半身不遂，筋脉拘挛，骨节酸痛，湿热黄疸，骨蒸潮热，小儿疳积发热。
伸筋草：味苦、微辛，性温。归肝、脾、肾经。有祛风除湿，舒筋活络的功效。用于关节酸痛，屈伸不利。
艾叶：味辛、苦，温。归肝、脾、肾经。温经止血，散寒止痛；外用祛湿止痒。用于吐血，衄血，崩漏，月经过多，胎漏下血，少腹冷痛，经寒不调，宫冷不孕；外治皮肤瘙痒。醋艾炭温经止血，用于虚寒性出血。
鸡血藤：味苦、甘，温。归肝、肾经。活血补血，调经止痛，舒筋活络。用于月经不调，痛经，经闭，风湿痹痛，麻木瘫痪，血虚萎黄。
透骨草：味辛，性温。入肝、肾经。祛风除湿，舒筋活血，散瘀消肿，解毒止痛。风湿痹痛，筋骨挛缩，寒湿脚气，腰部扭伤，瘫痪，闭经，阴囊湿疹，疮疖肿毒。
降香：味辛，温。归肝、脾经。化瘀止血，理气止痛。用于吐血，衄血，外伤出血，肝郁胁痛，胸痹刺痛，跌扑伤痛，呕吐腹痛。
木瓜：味酸，性温。归肝、脾经。有舒筋活络，和胃化湿的功效。用于治疗湿痹拘挛，腰膝关节酸重疼痛，暑湿吐泻，转筋挛痛，脚气水肿。
黄芪：味甘，微温。归肺、脾、肝、肾经。益气固表、敛汗固脱哦、托疮生肌、利水消肿。用于治疗气虚乏力，中气下陷、久泻脱肛、便血崩漏、表虚自汗你、痈疽难溃、久溃不敛、血虚萎黄、内热消渴、慢性肾炎、蛋白尿、糖尿病等。
熟地：味甘，微温。归肝、肾经。补血养阴，填精益髓。可用于血虚萎黄，眩晕，心悸失眠，月经不调，崩漏等症，亦可用于肾阴不足的潮热骨蒸、盗汗、遗精、消渴等症。
黄精：味甘，性平。归脾、肺、肾经。补气养阴，健脾，润肺，益肾。用于脾胃气虚，体倦乏力，胃阴不足，口干食少，肺虚燥咳，劳嗽咳血，精血不足，腰膝酸软，须发早白，内热消渴。
本发明的有益效果是：本发明以多味中药为原料，科学配伍，各原料药之间协同作用，具有活血散瘀、消肿止痛的功效，可扩张血管，降低血管阻力，显著增加肢体血流量，改善微循环，能降低血小板表面活性，抑制血小板凝集，预防血栓的形成，可加速局部血肿的吸收，川牛膝、苏木、桑枝、木瓜、黄芩、熟地、黄精在发挥药效的同时可以中和当归、独活、川断、羌活、乳香、没药、川穹、鸡血藤等的辛苦味，改善口感，本发明可用于股骨头坏死、腰椎间盘突出、铁打损伤、骨折、骨质增生、风湿类风湿性关节炎、肢体麻木等恢复期治疗，口服口感好，疗程短，见效快、治疗率高，值得推广。
具体实施方式
实施例1
原料组分：当归10g、独活5g、川断10g、羌活10g、红花10g、乳香10g、川牛膝15g、没药10g、苏木10g、桑枝1g、威灵仙5g、赤芍10g、川穹10g、秦艽10g、伸筋草15g、艾叶15g、鸡血藤10g、透骨草10g、降香10g、木瓜10g、黄芩5g、熟地3g、黄精10g、茶油2g、紫苏籽油3g、蜂蜜10g。
制备工艺：
（1）、将当归、独活、川断、羌活、乳香、没药、川穹、鸡血藤加水浸泡4h，然后在70℃、2MPa的蒸汽下灭菌2min；
（2）、将步骤（1）灭菌后的原料加其重10倍的水磨浆，过100目筛得浆料；
（3）、将红花、威灵仙、赤芍、秦艽、伸筋草、艾叶、透骨草、降香洗净后烘干，在铁锅内加入茶油和紫苏籽油，然后加入蜂蜜，炒制10min，磨成粉面，过100目筛；
（4）、将川牛膝、苏木、桑枝、木瓜、黄芩、熟地、黄精一起洗净脱水，在80℃下杀菌烘干，磨成粉面，过100目筛；
（5）、将步骤（2）、（3）、（4）的物料混合，在120℃、真空度-0.03MPa下杀菌10s，在60℃下乳化、均质，最后浓缩、喷雾干燥，自动包装封口得成品，每包50g。
用法与用量：口服，一次一包，每日两次。
实施例2
原料组分：当归15g、独活10g、川断12g、羌活15g、红花15g、乳香15g、川牛膝18g、没药12g、苏木15g、桑枝3g、威灵仙10g、赤芍12g、川穹15g、秦艽15g、伸筋草20g、艾叶20g、鸡血藤15g、透骨草15g、降香12g、木瓜15g、黄芩8g、熟地10g、黄精12g、茶油3g、紫苏籽油3g、蜂蜜12g。
制备工艺：
（1）、将当归、独活、川断、羌活、乳香、没药、川穹、鸡血藤加水浸泡3h，然后在80℃、1.5MPa的蒸汽下灭菌3min；
（2）、将步骤（1）灭菌后的原料加其重12倍的水磨浆，过100目筛得浆料；
（3）、将红花、威灵仙、赤芍、秦艽、伸筋草、艾叶、透骨草、降香洗净后烘干，在铁锅内加入茶油和紫苏籽油，然后加入蜂蜜，炒制15min，磨成粉面，过100目筛；
（4）、将川牛膝、苏木、桑枝、木瓜、黄芩、熟地、黄精一起洗净脱水，在100℃下杀菌烘干，磨成粉面，过100目筛；
（5）、将步骤（2）、（3）、（4）的物料混合，在120-150℃、真空度-0.05 MPa下杀菌5s，在80℃下乳化、均质，最后浓缩、喷雾干燥，自动包装封口得成品，每包50g。
用法与用量：口服，一次一包，每日两次。
实施例3
原料组分：当归20g、独活15g、川断15g、羌活20g、红花20g、乳香20g、川牛膝20g、没药15g、苏木20g、桑枝5g、威灵仙15g、赤芍15g、川穹15g、秦艽20g、伸筋草25g、艾叶25g、鸡血藤20g、透骨草20g、降香15g、木瓜20g、黄芩10g、熟地12g、黄精15g、茶油5g、紫苏籽油5g、蜂蜜15g。
制备工艺：
（1）、将当归、独活、川断、羌活、乳香、没药、川穹、鸡血藤加水浸泡5h，然后在80℃、3MPa的蒸汽下灭菌1min；
（2）、将步骤（1）灭菌后的原料加其重11倍的水磨浆，过100目筛得浆料；
（3）、将红花、威灵仙、赤芍、秦艽、伸筋草、艾叶、透骨草、降香洗净后烘干，在铁锅内加入茶油和紫苏籽油，然后加入蜂蜜，炒制13min，磨成粉面，过100目筛；
（4）、将川牛膝、苏木、桑枝、木瓜、黄芩、熟地、黄精一起洗净脱水，在90℃下杀菌烘干，磨成粉面，过100目筛；
（5）、将步骤（2）、（3）、（4）的物料混合，在140℃、真空度-0.04 MPa下杀菌8s，在70℃下乳化、均质，最后浓缩、喷雾干燥，自动包装封口得成品，每包50g。
用法与用量：口服，一次一包，每日两次。

Claims (5)

1.一种活血止痛散，其特征在于：包括以下重量份数的原料：当归10-20份、独活5-15份、川断10-15份、羌活10-20份、红花10-20份、乳香10-20份、川牛膝15-20份、没药10-15份、苏木10-20份、桑枝1-5份、威灵仙5-15份、赤芍10-15份、川穹10-15份、秦艽10-20份、伸筋草15-25份、艾叶15-25份、鸡血藤10-20份、透骨草10-20份、降香10-15份、木瓜10-20份、黄芩5-10份、熟地3-12份、黄精10-15份、茶油2-5份、紫苏籽油3-5份、蜂蜜10-15份。
2.根据权利要求1所述的一种活血止痛散，其特征在于：包括以下重量份数的原料：当归15份、独活10份、川断12份、羌活15份、红花15份、乳香15份、川牛膝18份、没药12份、苏木15份、桑枝3份、威灵仙10份、赤芍12份、川穹15份、秦艽15份、伸筋草20份、艾叶20份、鸡血藤15份、透骨草15份、降香12份、木瓜15份、黄芩8份、熟地10份、黄精12份、茶油3份、紫苏籽油3份、蜂蜜12份。
3.根据权利要求1或2所述的一种活血止痛散的制备方法，其特征在于：包括以下步骤：
（1）、将当归、独活、川断、羌活、乳香、没药、川穹、鸡血藤加水浸泡3-6h，然后在60-80℃的蒸汽下灭菌1-3min；
（2）、将步骤（1）灭菌后的原料加其重10-12倍的水磨浆，过100目筛得浆料；
（3）、将红花、威灵仙、赤芍、秦艽、伸筋草、艾叶、透骨草、降香洗净后烘干，在铁锅内加入茶油和紫苏籽油，然后加入蜂蜜，炒制10-15min，磨成粉面，过100目筛；
（4）、将川牛膝、苏木、桑枝、木瓜、黄芩、熟地、黄精一起洗净脱水，在80-100℃下杀菌烘干，磨成粉面，过100目筛；
（5）、将步骤（2）、（3）、（4）的物料混合，杀菌、乳化、均质，最后浓缩、喷雾干燥，自动包装封口得成品。
4.根据权利要求3所述的一种活血止痛散的制备方法，其特征在于：步骤（1）中蒸汽压力为1.5-3MPa。
5.根据权利要求3所述的一种活血止痛散的制备方法，其特征在于：步骤（5）中混合物料在120-150℃、真空度-0.03— -0.05 MPa下杀菌5-10s；乳化温度为60-80℃。
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Application publication date: 20171215