CN107441386A - A kind of infantile pneumonia medicine and preparation method thereof - Google Patents

A kind of infantile pneumonia medicine and preparation method thereof Download PDF

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CN107441386A
CN107441386A CN201710929327.0A CN201710929327A CN107441386A CN 107441386 A CN107441386 A CN 107441386A CN 201710929327 A CN201710929327 A CN 201710929327A CN 107441386 A CN107441386 A CN 107441386A
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infantile pneumonia
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凌静静
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Abstract

The invention discloses a kind of infantile pneumonia medicine.It is made up of the raw material of following parts by weight:38 parts of cape jasmine, 4 10 parts of chamomile, 3 10 parts of lophatherum gracile, 49 parts of earthworm, 5 15 parts of Paris polyphylla, 6 15 parts of oriental wormwood, 3 10 parts of schefflera arboricola, 5 15 parts of cornu caprae hircus.Infantile pneumonia medicine prepared by the present invention, mouthfeel is not bitter, without any side effects, and therapeutic effect is good, cure rate is high, is not easy to recur after healing, and it is prepared prepares extraction powder and the method mixed using substep, preparation method is novel, simply, is adapted to the needs of large-scale industrial production.

Description

A kind of infantile pneumonia medicine and preparation method thereof
Technical field
The invention belongs to paediatrics disease medicine preparing technical field, and in particular to a kind of infantile pneumonia medicine and its Preparation method.
Background technology
Infantile pneumonia is the common disease of infant period, and the northern area of China is common with winter-spring season, is Infant and child deaths Common cause.Pneumonia be as pathogenic infection or suction amniotic fluid and oils and allergic reaction etc. caused by lung inflammation, mainly Clinical manifestation is generates heat, coughed, being short of breath, having difficulty in breathing and lung's rale etc..Infantile pneumonia morbidity is very fast, and easily multiple Hair, the drug side-effect of traditional treatment pneumonia is larger, easily leaves sequelae.
Patent 201410032618.6 discloses a kind of Chinese medicine preparation and preparation method for treating infantile pneumonia.Chinese medicine preparation The raw material of active ingredient forms:Caulis clematidis armandii, pear skin, Momordica grosvenori, Ligusticum wallichii, lotus rhizome, Sambucus chinensis, Chinese mesona herb, nauclea officinalis, lotus root, Cypress branch, wild ginger, lotus leaf, Flos Hibisci Rosae-Sinensis, tinosporae, witloof and ginkgo.The medicine composite for curing course for the treatment of is grown, easily multiple after healing Hair.
Patent 201210298498.5 discloses a kind of Chinese medicine composition for treating infantile pneumonia, and selection, which has, opens lung a surname Close, resolving sputum removing toxic substances, it is the Chinese medicine aquatic malachium herb that replenishes qi to invigorate the spleen, scandent hedyotis herb, balloonflower root, the dried immature fruit of citron orange, aster, bulbus fritillariae cirrhosae, radix glycyrrhizae, adenophora tetraphylla, white Decoction is made in art, citron, and through our hospital's clinical test, cure rate reaches 57.0%, and total effective rate reaches 98.0%, especially in disease In terms of shape improvement, as it is relieving cough and asthma, treat number of days and number of days of bringing down a fever in terms for the treatment of group be better than control group, still, the Chinese traditional medicine composition Thing side effect is larger, is easily recurred after healing.
The content of the invention
It is an object of the invention to provide a kind of infantile pneumonia medicine and preparation method thereof.
A kind of infantile pneumonia medicine, is made up of the raw material of following parts by weight:Cape jasmine 3-8 parts, chamomile 4-10 parts, Lophatherum gracile 3-10 parts, earthworm 4-9 parts, Paris polyphylla 5-15 parts, oriental wormwood 6-15 parts, schefflera arboricola 3-10 parts, cornu caprae hircus 5-15 parts.
The medicine also includes cottonrose hibiscus leaf 3-8 parts.
The medicine also includes the root of straight ladybell 5-9 parts.
The medicine also includes cat breast 5-9 parts.
The preparation method of above-mentioned infantile pneumonia medicine, is carried out in accordance with the following steps:
(1)Cape jasmine 3-8 parts are taken, chamomile 4-10 parts, lophatherum gracile 3-10 parts, mixing, are clayed into power, add 3-5 times of parts by weight Water refluxing extraction 3 times, merging filtrate, be evaporated and powders A be made;
(2)Earthworm 4-9 parts are taken, Paris polyphylla 5-15 parts, oriental wormwood 6-15 parts, is put into marmite, does not have with water logging, are heated to 60-80 DEG C, are steamed Boil 1-3 hours, add 2 parts of sodium tartrates, then boiling 6-8 hours, be cooled to room temperature, stand 1-3 hours, take supernatant, be evaporated Powder B is made;
(3)Schefflera arboricola 3-10 parts are taken, cornu caprae hircus 5-15 parts, add 0.1-1 part yeast fermentation broths, 25-35 DEG C ferments 3-6 days, shines Dry or drying, clays into power, and the water refluxing extraction of 3-5 times of parts by weight of addition 3 times, merging filtrate, is evaporated and powder C is made;
(4)By powders A, powder B, powder C is well mixed, and is loaded capsule and is made.
Yeast bacterial content is 3-7X10 in the yeast fermentation broth8cfu。
The step(1)In be additionally added cottonrose hibiscus leaf 3-8 parts.
The step(2)In be additionally added the root of straight ladybell 5-9 parts.
The step(3)In be additionally added cat breast 5-9 parts.
Beneficial effects of the present invention:Infantile pneumonia medicine prepared by the present invention, mouthfeel is not bitter, without the secondary work of any poison With therapeutic effect is good, and cure rate is high, is not easy to recur after healing, and it is prepared prepares extraction powder and the side mixed using substep Method, preparation method is novel, simply, is adapted to the needs of large-scale industrial production.
Embodiment
With reference to specific embodiment, the present invention will be further described.
Embodiment 1
A kind of infantile pneumonia medicine, is made up of the raw material of following parts by weight:5 parts of cape jasmine, 6 parts of chamomile, lophatherum gracile 7 Part, 5 parts of earthworm, 12 parts of Paris polyphylla, 8 parts of oriental wormwood, 7 parts of schefflera arboricola, 11 parts of cornu caprae hircus.
The preparation method of above-mentioned infantile pneumonia medicine, is carried out in accordance with the following steps:
(1)5 parts of cape jasmine is taken, 6 parts of chamomile, 7 parts of lophatherum gracile, mixing, is clayed into power, the water backflow for adding 4 times of parts by weight carries Take 3 times, merging filtrate, be evaporated and powders A is made;
(2)5 parts of earthworm is taken, 12 parts of Paris polyphylla, 8 parts of oriental wormwood, is put into marmite, does not have with water logging, 70 DEG C is heated to, boiling 2 hours, adds Enter 2 parts of sodium tartrates, then boiling 7 hours, room temperature is cooled to, 2 hours is stood, takes supernatant, be evaporated and powder B is made;
(3)7 parts of schefflera arboricola is taken, 11 parts of cornu caprae hircus, adds 0.5 part of yeast fermentation broth, 28 DEG C ferment 4 days, dry or dry, wear into Powder, the water refluxing extraction of 4 times of parts by weight of addition 3 times, merging filtrate, is evaporated and powder C is made;Ferment in the yeast fermentation broth Female bacterial content is 5X108cfu;
(4)By powders A, powder B, powder C is well mixed, and is loaded capsule and is made.
Embodiment 2
A kind of infantile pneumonia medicine, is made up of the raw material of following parts by weight:3 parts of cape jasmine, 4 parts of chamomile, lophatherum gracile 3 Part, 4 parts of earthworm, 5 parts of Paris polyphylla, 6 parts of oriental wormwood, 3 parts of schefflera arboricola, 5 parts of cornu caprae hircus.
The preparation method of above-mentioned infantile pneumonia medicine, is carried out in accordance with the following steps:
(1)3 parts of cape jasmine is taken, 4 parts of chamomile, 3 parts of lophatherum gracile, mixing, is clayed into power, the water backflow for adding 3 times of parts by weight carries Take 3 times, merging filtrate, be evaporated and powders A is made;
(2)4 parts of earthworm is taken, 5 parts of Paris polyphylla, 6 parts of oriental wormwood, is put into marmite, does not have with water logging, 60 DEG C is heated to, boiling 1 hour, adds Enter 2 parts of sodium tartrates, then boiling 6 hours, room temperature is cooled to, 1 hour is stood, takes supernatant, be evaporated and powder B is made;
(3)3 parts of schefflera arboricola is taken, 5 parts of cornu caprae hircus, adds 0.1 part of yeast fermentation broth, 25 DEG C ferment 3 days, dry or dry, wear into Powder, the water refluxing extraction of 3 times of parts by weight of addition 3 times, merging filtrate, is evaporated and powder C is made;Ferment in the yeast fermentation broth Female bacterial content is 3X108cfu;
(4)By powders A, powder B, powder C is well mixed, and is loaded capsule and is made.
Embodiment 3
A kind of infantile pneumonia medicine, is made up of the raw material of following parts by weight:8 parts of cape jasmine, 10 parts of chamomile, lophatherum gracile 10 Part, 9 parts of earthworm, 15 parts of Paris polyphylla, 15 parts of oriental wormwood, 10 parts of schefflera arboricola, 15 parts of cornu caprae hircus.
The preparation method of above-mentioned infantile pneumonia medicine, is carried out in accordance with the following steps:
(1)8 parts of cape jasmine is taken, 10 parts of chamomile, 10 parts of lophatherum gracile, mixing, is clayed into power, adds the water backflow of 5 times of parts by weight Extraction 3 times, merging filtrate, is evaporated and powders A is made;
(2)9 parts of earthworm is taken, 15 parts of Paris polyphylla, 15 parts of oriental wormwood, is put into marmite, does not have with water logging, is heated to 80 DEG C, boiling 3 hours, 2 parts of sodium tartrates, then boiling 8 hours are added, is cooled to room temperature, 3 hours is stood, takes supernatant, be evaporated and powder B is made;
(3)10 parts of schefflera arboricola is taken, 15 parts of cornu caprae hircus, adds 1 part of yeast fermentation broth, 35 DEG C ferment 6 days, dry or dry, wear into Powder, the water refluxing extraction of 5 times of parts by weight of addition 3 times, merging filtrate, is evaporated and powder C is made;Ferment in the yeast fermentation broth Female bacterial content is 7X108cfu;
(4)By powders A, powder B, powder C is well mixed, and is loaded capsule and is made.
Embodiment 4
A kind of infantile pneumonia medicine, is made up of the raw material of following parts by weight:5 parts of cape jasmine, 6 parts of chamomile, lophatherum gracile 7 Part, 5 parts of earthworm, 12 parts of Paris polyphylla, 8 parts of oriental wormwood, 7 parts of schefflera arboricola, 11 parts of cornu caprae hircus, cottonrose hibiscus leaf 3-8 parts.
The preparation method of above-mentioned infantile pneumonia medicine, is carried out in accordance with the following steps:
(1)5 parts of cape jasmine is taken, 6 parts of chamomile, 7 parts of lophatherum gracile, cottonrose hibiscus leaf 3-8 parts, mixing, is clayed into power, adds 4 times of parts by weight Several water refluxing extraction 3 times, merging filtrate, is evaporated and powders A is made;
(2)5 parts of earthworm is taken, 12 parts of Paris polyphylla, 8 parts of oriental wormwood, is put into marmite, does not have with water logging, 70 DEG C is heated to, boiling 2 hours, adds Enter 2 parts of sodium tartrates, then boiling 7 hours, room temperature is cooled to, 2 hours is stood, takes supernatant, be evaporated and powder B is made;
(3)7 parts of schefflera arboricola is taken, 11 parts of cornu caprae hircus, adds 0.5 part of yeast fermentation broth, 28 DEG C ferment 4 days, dry or dry, wear into Powder, the water refluxing extraction of 4 times of parts by weight of addition 3 times, merging filtrate, is evaporated and powder C is made;Ferment in the yeast fermentation broth Female bacterial content is 5X108cfu;
(4)By powders A, powder B, powder C is well mixed, and is loaded capsule and is made.
Embodiment 5
A kind of infantile pneumonia medicine, is made up of the raw material of following parts by weight:5 parts of cape jasmine, 6 parts of chamomile, lophatherum gracile 7 Part, 5 parts of earthworm, 12 parts of Paris polyphylla, 8 parts of oriental wormwood, 7 parts of schefflera arboricola, 11 parts of cornu caprae hircus, the root of straight ladybell 5-9 parts.
The preparation method of above-mentioned infantile pneumonia medicine, is carried out in accordance with the following steps:
(1)5 parts of cape jasmine is taken, 6 parts of chamomile, 7 parts of lophatherum gracile, mixing, is clayed into power, the water backflow for adding 4 times of parts by weight carries Take 3 times, merging filtrate, be evaporated and powders A is made;
(2)5 parts of earthworm is taken, 12 parts of Paris polyphylla, 8 parts of oriental wormwood, the root of straight ladybell 5-9 parts, is put into marmite, does not have with water logging, is heated to 70 DEG C, is steamed Boil 2 hours, add 2 parts of sodium tartrates, then boiling 7 hours, be cooled to room temperature, stand 2 hours, take supernatant, be evaporated and powder is made Last B;
(3)7 parts of schefflera arboricola is taken, 11 parts of cornu caprae hircus, adds 0.5 part of yeast fermentation broth, 28 DEG C ferment 4 days, dry or dry, wear into Powder, the water refluxing extraction of 4 times of parts by weight of addition 3 times, merging filtrate, is evaporated and powder C is made;Ferment in the yeast fermentation broth Female bacterial content is 5X108cfu;
(4)By powders A, powder B, powder C is well mixed, and is loaded capsule and is made.
Embodiment 6
A kind of infantile pneumonia medicine, is made up of the raw material of following parts by weight:5 parts of cape jasmine, 6 parts of chamomile, lophatherum gracile 7 Part, 5 parts of earthworm, 12 parts of Paris polyphylla, 8 parts of oriental wormwood, 7 parts of schefflera arboricola, 11 parts of cornu caprae hircus, cat breast 5-9 parts.
The preparation method of above-mentioned infantile pneumonia medicine, is carried out in accordance with the following steps:
(1)5 parts of cape jasmine is taken, 6 parts of chamomile, 7 parts of lophatherum gracile, mixing, is clayed into power, the water backflow for adding 4 times of parts by weight carries Take 3 times, merging filtrate, be evaporated and powders A is made;
(2)5 parts of earthworm is taken, 12 parts of Paris polyphylla, 8 parts of oriental wormwood, is put into marmite, does not have with water logging, 70 DEG C is heated to, boiling 2 hours, adds Enter 2 parts of sodium tartrates, then boiling 7 hours, room temperature is cooled to, 2 hours is stood, takes supernatant, be evaporated and powder B is made;
(3)7 parts of schefflera arboricola is taken, 11 parts of cornu caprae hircus, cat breast 5-9 parts, adds 0.5 part of yeast fermentation broth, 28 DEG C ferment 4 days, dry Or drying, clay into power, the water refluxing extraction of 4 times of parts by weight of addition 3 times, merging filtrate, be evaporated and powder C is made;The ferment Yeast bacterial content is 5X10 in female zymotic fluid8cfu;
(4)By powders A, powder B, powder C is well mixed, and is loaded capsule and is made.
Embodiment 7
A kind of infantile pneumonia medicine, is made up of the raw material of following parts by weight:5 parts of cape jasmine, 6 parts of chamomile, lophatherum gracile 7 Part, 5 parts of earthworm, 12 parts of Paris polyphylla, 8 parts of oriental wormwood, 7 parts of schefflera arboricola, 11 parts of cornu caprae hircus, sharp 7 parts of leaf halogen fern.
The preparation method of above-mentioned infantile pneumonia medicine, is carried out in accordance with the following steps:
(1)5 parts of cape jasmine is taken, 6 parts of chamomile, 7 parts of lophatherum gracile, sharp 7 parts of leaf halogen fern, mixing, is clayed into power, adds 4 times of parts by weight Several water refluxing extraction 3 times, merging filtrate, is evaporated and powders A is made;
(2)5 parts of earthworm is taken, 12 parts of Paris polyphylla, 8 parts of oriental wormwood, is put into marmite, does not have with water logging, 70 DEG C is heated to, boiling 2 hours, adds Enter 2 parts of sodium tartrates, then boiling 7 hours, room temperature is cooled to, 2 hours is stood, takes supernatant, be evaporated and powder B is made;
(3)7 parts of schefflera arboricola is taken, 11 parts of cornu caprae hircus, adds 0.5 part of yeast fermentation broth, 28 DEG C ferment 4 days, dry or dry, wear into Powder, the water refluxing extraction of 4 times of parts by weight of addition 3 times, merging filtrate, is evaporated and powder C is made;Ferment in the yeast fermentation broth Female bacterial content is 5X108cfu;
(4)By powders A, powder B, powder C is well mixed, and is loaded capsule and is made.
Embodiment 8
A kind of infantile pneumonia and tuberculosis treatment medicine, are made up of the raw material of following parts by weight:5 parts of cape jasmine, 6 parts of chamomile, 7 parts of lophatherum gracile, 5 parts of earthworm, 12 parts of Paris polyphylla, 8 parts of oriental wormwood, 7 parts of schefflera arboricola, 11 parts of cornu caprae hircus, 7 parts of hand lamp moss.
The preparation method of above-mentioned infantile pneumonia medicine, is carried out in accordance with the following steps:
(1)5 parts of cape jasmine is taken, 6 parts of chamomile, 7 parts of lophatherum gracile, mixing, is clayed into power, the water backflow for adding 4 times of parts by weight carries Take 3 times, merging filtrate, be evaporated and powders A is made;
(2)5 parts of earthworm is taken, 12 parts of Paris polyphylla, 8 parts of oriental wormwood, 7 parts of hand lamp moss, is put into marmite, does not have with water logging, is heated to 70 DEG C, is steamed Boil 2 hours, add 2 parts of sodium tartrates, then boiling 7 hours, be cooled to room temperature, stand 2 hours, take supernatant, be evaporated and powder is made Last B;
(3)7 parts of schefflera arboricola is taken, 11 parts of cornu caprae hircus, adds 0.5 part of yeast fermentation broth, 28 DEG C ferment 4 days, dry or dry, wear into Powder, the water refluxing extraction of 4 times of parts by weight of addition 3 times, merging filtrate, is evaporated and powder C is made;Ferment in the yeast fermentation broth Female bacterial content is 5X108cfu;
(4)By powders A, powder B, powder C is well mixed, and is loaded capsule and is made.
Embodiment 9
A kind of infantile pneumonia medicine, is made up of the raw material of following parts by weight:5 parts of cape jasmine, 6 parts of chamomile, lophatherum gracile 7 Part, 5 parts of earthworm, 12 parts of Paris polyphylla, 8 parts of oriental wormwood, 7 parts of schefflera arboricola, 11 parts of cornu caprae hircus.
The preparation method of above-mentioned infantile pneumonia medicine, is carried out in accordance with the following steps:
(1)5 parts of cape jasmine is taken, 6 parts of chamomile, 7 parts of lophatherum gracile, mixing, is clayed into power, the water backflow for adding 4 times of parts by weight carries Take 3 times, merging filtrate, be evaporated and powders A is made;
(2)5 parts of earthworm is taken, 12 parts of Paris polyphylla, 8 parts of oriental wormwood, is put into marmite, does not have with water logging, 70 DEG C is heated to, boiling 2 hours, adds Enter 2 parts of sodium tartrates, then boiling 7 hours, room temperature is cooled to, 2 hours is stood, takes supernatant, be evaporated and powder B is made;
(3)7 parts of schefflera arboricola is taken, 11 parts of cornu caprae hircus, adds 0.5 portion of Han Shi acetobacter zymotic fluid, 28 DEG C ferment 4 days, dry or dry It is dry, clay into power, the water refluxing extraction of 4 times of parts by weight of addition 3 times, merging filtrate, be evaporated and powder C is made;The Han Shi vinegar Han Shi acetobacters content is 5X10 in bacillus fermentation liquid8cfu;
(4)By powders A, powder B, powder C is well mixed, and is loaded capsule and is made.
Comparative example 1
A kind of infantile pneumonia medicine, is made up of the raw material of following parts by weight:5 parts of cape jasmine, 6 parts of chamomile, lophatherum gracile 7 Part, 5 parts of earthworm, 12 parts of Paris polyphylla, 8 parts of oriental wormwood, 7 parts of schefflera arboricola, 11 parts of cornu caprae hircus.
The preparation method of above-mentioned infantile pneumonia medicine, is carried out in accordance with the following steps:
(1)5 parts of cape jasmine is taken, 6 parts of chamomile, 7 parts of lophatherum gracile, mixing, is clayed into power, the water backflow for adding 4 times of parts by weight carries Take 3 times, merging filtrate, be evaporated and powders A is made;
(2)5 parts of earthworm is taken, 12 parts of Paris polyphylla, 8 parts of oriental wormwood, is put into marmite, does not have with water logging, 70 DEG C is heated to, boiling 2 hours, adds Enter 2 parts of sodium tartrates, then boiling 7 hours, room temperature is cooled to, 2 hours is stood, takes supernatant, be evaporated and powder B is made;
(3)7 parts of schefflera arboricola is taken, 11 parts of cornu caprae hircus, adds 0.5 portion of acetobacter xylinum zymotic fluid, 28 DEG C ferment 4 days, dry or dry, Clay into power, the water refluxing extraction of 4 times of parts by weight of addition 3 times, merging filtrate, be evaporated and powder C is made;The acetobacter xylinum hair Acetobacter xylinum content is 5X10 in zymotic fluid8cfu;
(4)By powders A, powder B, powder C is well mixed, and is loaded capsule and is made.
Comparative example 2
A kind of infantile pneumonia medicine, is made up of the raw material of following parts by weight:5 parts of cape jasmine, 6 parts of chamomile, lophatherum gracile 7 Part, 5 parts of earthworm, 12 parts of Paris polyphylla, 8 parts of oriental wormwood, 7 parts of schefflera arboricola, 11 parts of cornu caprae hircus.
The preparation method of above-mentioned infantile pneumonia medicine, is carried out in accordance with the following steps:
(1)5 parts of cape jasmine is taken, 6 parts of chamomile, 7 parts of lophatherum gracile, mixing, is clayed into power, the water backflow for adding 4 times of parts by weight carries Take 3 times, merging filtrate, be evaporated and powders A is made;
(2)5 parts of earthworm is taken, 12 parts of Paris polyphylla, 8 parts of oriental wormwood, is put into marmite, does not have with water logging, 70 DEG C is heated to, boiling 2 hours, adds Enter 2 parts of potassium tartrates, then boiling 7 hours, room temperature is cooled to, 2 hours is stood, takes supernatant, be evaporated and powder B is made;
(3)7 parts of schefflera arboricola is taken, 11 parts of cornu caprae hircus, adds 0.5 part of yeast fermentation broth, 28 DEG C ferment 4 days, dry or dry, wear into Powder, the water refluxing extraction of 4 times of parts by weight of addition 3 times, merging filtrate, is evaporated and powder C is made;Ferment in the yeast fermentation broth Female bacterial content is 5X108cfu;
(4)By powders A, powder B, powder C is well mixed, and is loaded capsule and is made.
Comparative example 3
A kind of infantile pneumonia medicine, is made up of the raw material of following parts by weight:5 parts of cape jasmine, 6 parts of chamomile, lophatherum gracile 7 Part, 5 parts of earthworm, 12 parts of Paris polyphylla, 8 parts of oriental wormwood, 7 parts of schefflera arboricola, 11 parts of cornu caprae hircus.
The preparation method of above-mentioned infantile pneumonia medicine, is carried out in accordance with the following steps:
(1)5 parts of cape jasmine is taken, 6 parts of chamomile, 7 parts of lophatherum gracile, mixing, is clayed into power, the water backflow for adding 4 times of parts by weight carries Take 3 times, merging filtrate, be evaporated and powders A is made;
(2)5 parts of earthworm is taken, 12 parts of Paris polyphylla, 8 parts of oriental wormwood, is put into marmite, does not have with water logging, 70 DEG C is heated to, boiling 2 hours, adds Enter 2 parts of sodium tartrates, then boiling 7 hours, room temperature is cooled to, 2 hours is stood, takes supernatant, be evaporated and powder B is made;
(3)7 parts of schefflera arboricola is taken, 11 parts of cornu caprae hircus, is clayed into power, the water refluxing extraction of 4 times of parts by weight of addition 3 times, merges filter Liquid, it is evaporated and powder C is made;
(4)By powders A, powder B, powder C is well mixed, and is loaded capsule and is made.
Experimental example 1:
Infantile pneumonia patient 1000 to be selected, is divided into 10 groups, every group of 100 people, symptom is that heating, food refusal, agitation, asthma such as suppress at the symptom, Early stage body temperature is 38~39 DEG C, also up to 40 DEG C.In addition to respiratory symptom, infant can be with One's spirits are drooping, dysphoria, food It is intended to depressed, trembles, the constitutional symptom such as diarrhoea.The common food refusal of young infant, milk of choking, vomiting and expiratory dyspnea.Embodiment 1-7 is taken, Embodiment 9, comparative example 1-3 medicine, daily 20g, divide 2 times and take, after taking 30, count cure rate, system is tracked after half a year Recurrence rate is counted, as shown in table 1:
Table 1
Group Every group of patient's number Cure rate Recurrence rate
Embodiment 1 100 75% 6%
Embodiment 2 100 76% 7%
Embodiment 3 100 75% 6%
Embodiment 4 100 85% 1%
Embodiment 5 100 86% 1%
Embodiment 6 100 87% 2%
Embodiment 7 100 92% 1%
Embodiment 9 100 93% 1%
Comparative example 1 100 56% 12%
Comparative example 2 100 54% 13%
Comparative example 3 100 56% 11%
As can be seen from Table 1, embodiment 4-6 cure rate is above embodiment 1, and recurrence rate is less than embodiment 1, with embodiment 1 Compare, embodiment 4-6 other conditions are identical with embodiment 1, only respectively in embodiment 4-6 to add lotus more Leaf, the root of straight ladybell, cat breast, it was demonstrated that cottonrose hibiscus leaf, the root of straight ladybell, cat breast have the effect for the treatment of infantile pneumonia and preventing from recurring after curing.Implement Example 7, the cure rate of embodiment 9 are above embodiment 1, and recurrence rate is less than embodiment 1, compared with Example 1, embodiment 7 and 9 Other conditions are identical with embodiment 1, only not in embodiment 7 not add sharp leaf halogen fern more, by Han Shi vinegar in embodiment 9 Bacillus fermentation liquid replaces yeast fermentation broth, it was demonstrated that sharp leaf halogen fern, the addition of Han Shi acetobacter zymotic fluids have treatment infantile pneumonia And the effect of preventing from recurring after curing.The cure rate of comparative example 1 is less than embodiment 9, and high recurrence rate is in embodiment 9, with embodiment 9 Compare, other experiment conditions are identical, and Han Shi acetobacter zymotic fluids only are replaced with into acetobacter xylinum zymotic fluid, it is seen that wood Not the effect of acetobacter zymotic fluid does not treat infantile pneumonia and prevents from recurring after curing.The cure rate of comparative example 2 is less than implementation Example 1, high recurrence rate is in embodiment 1, and compared with Example 1, other experiment conditions are identical, only replace sodium tartrate For potassium tartrate, it is seen that potassium tartrate is added in preparation process and does not have the work(treated infantile pneumonia and prevent from recurring after curing Effect.The cure rate of comparative example 3 is less than embodiment 1, and high recurrence rate is in embodiment 1, and compared with Example 1, other experiment conditions are complete It is exactly the same, only in step(3)Processing procedure in do not add yeast fermentation broth, it is seen that seven treated leaves of yeast fermentation broth Lotus, cornu caprae hircus just have the effect for the treatment of infantile pneumonia and preventing from recurring after curing, not handled without above-mentioned effect.
Experimental example 2:
Children lunger 200 is selected, is divided into 2 groups, every group of 100 people, symptom is to have closer tuberculosis contact history, onset Can suddenly can delay, mostly low-heat, night sweat, it is weak, receive it is poor, become thin;Respiratory symptom has cough, expectoration, spitting of blood, pectoralgia, different journeys Spend uncomfortable in chest or expiratory dyspnea.Embodiment 1 is taken, the medicine of embodiment 8, daily 20g, divides 2 times and takes, after taking 30, statistics Cure rate, tracking statistics recurrence rate after half a year, as shown in table 2:
Table 2
Group Every group of patient's number Cure rate Recurrence rate
Embodiment 1 100 12% 12%
Embodiment 8 100 72% 3%
As can be seen from Table 1, the cure rate of embodiment 8 is significantly larger than embodiment 1, and recurrence rate is less than embodiment 1, with embodiment 1 Compare, other conditions are identical, and only embodiment more than 8 adds hand lamp moss, it is seen that hand lamp moss has treatment Lungs of Children knot The effect of core.

Claims (9)

1. a kind of infantile pneumonia medicine, it is characterised in that be made up of the raw material of following parts by weight:Cape jasmine 3-8 parts, ocean are sweet Chrysanthemum 4-10 parts, lophatherum gracile 3-10 parts, earthworm 4-9 parts, Paris polyphylla 5-15 parts, oriental wormwood 6-15 parts, schefflera arboricola 3-10 parts, cornu caprae hircus 5-15 Part.
2. infantile pneumonia medicine according to claim 1, it is characterised in that the medicine also includes cottonrose hibiscus leaf 3-8 parts.
3. infantile pneumonia medicine according to claim 1, it is characterised in that the medicine also includes the root of straight ladybell 5-9 parts.
4. infantile pneumonia medicine according to claim 1, it is characterised in that the medicine also includes cat breast 5-9 parts.
5. the preparation method of infantile pneumonia medicine described in claim 1, it is characterised in that carry out in accordance with the following steps:
(1)Cape jasmine 3-8 parts are taken, chamomile 4-10 parts, lophatherum gracile 3-10 parts, mixing, are clayed into power, add 3-5 times of parts by weight Water refluxing extraction 3 times, merging filtrate, be evaporated and powders A be made;
(2)Earthworm 4-9 parts are taken, Paris polyphylla 5-15 parts, oriental wormwood 6-15 parts, is put into marmite, does not have with water logging, are heated to 60-80 DEG C, are steamed Boil 1-3 hours, add 2 parts of sodium tartrates, then boiling 6-8 hours, be cooled to room temperature, stand 1-3 hours, take supernatant, be evaporated Powder B is made;
(3)Schefflera arboricola 3-10 parts are taken, cornu caprae hircus 5-15 parts, add 0.1-1 part yeast fermentation broths, 25-35 DEG C ferments 3-6 days, shines Dry or drying, clays into power, and the water refluxing extraction of 3-5 times of parts by weight of addition 3 times, merging filtrate, is evaporated and powder C is made;
(4)By powders A, powder B, powder C is well mixed, and is loaded capsule and is made.
6. the preparation method of infantile pneumonia medicine according to claim 1, it is characterised in that in the yeast fermentation broth Yeast bacterial content is 3-7X108cfu。
7. the preparation method of infantile pneumonia medicine according to claim 1, it is characterised in that the step(1)In also Add cottonrose hibiscus leaf 3-8 parts.
8. the preparation method of infantile pneumonia medicine according to claim 1, it is characterised in that the step(2)In also Add the root of straight ladybell 5-9 parts.
9. the preparation method of infantile pneumonia medicine according to claim 1, it is characterised in that the step(3)In also Add cat breast 5-9 parts.
CN201710929327.0A 2017-10-09 2017-10-09 A kind of infantile pneumonia medicine and preparation method thereof Withdrawn CN107441386A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107929433A (en) * 2017-12-19 2018-04-20 孙春苗 A kind of department of anesthesia is used for medicament of human body local anesthesia and preparation method thereof
CN108066649A (en) * 2018-01-09 2018-05-25 孙春苗 A kind of extract oral agent for treating rheumatoid arthritis and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20090094618A (en) * 2008-03-03 2009-09-08 김충정 Compositions for preventing or treating bacterial infections or inflammatory disease
CN103463401A (en) * 2013-09-25 2013-12-25 李燕宁 Asthma medicine for infants
CN104971259A (en) * 2015-07-25 2015-10-14 徐显廷 Traditional Chinese medicine oral liquid for treating infantile pneumonia

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20090094618A (en) * 2008-03-03 2009-09-08 김충정 Compositions for preventing or treating bacterial infections or inflammatory disease
CN103463401A (en) * 2013-09-25 2013-12-25 李燕宁 Asthma medicine for infants
CN104971259A (en) * 2015-07-25 2015-10-14 徐显廷 Traditional Chinese medicine oral liquid for treating infantile pneumonia

Non-Patent Citations (11)

* Cited by examiner, † Cited by third party
Title
《养生馆》编委会: "《《本草纲目》:天然花草养颜经》", 30 June 2013, 广东科技出版社 *
刘亚明: "《发酵技术在中医药中的应用》", 31 March 2010, 中国中医药出版社 *
刘绍贵等: "《临床常用中草药鉴别与应用》", 31 July 2015, 湖南科学技术出版社 *
周幸来等: "《常用中药临证经验荟萃》", 31 October 2012, 金盾出版社 *
徐树楠: "《中药临床应用大全》", 31 January 1999, 河北科学技术出版社 *
李书军等: "《肺结核》", 31 January 2016, 中国医药科技出版社 *
水嵨昇(日),公孙毅译: "《名医评析单味草药巧治病》", 31 May 2007, 北京科学技术出版社 *
王梅: "《实用中医养生大全》", 30 November 2009, 中医古籍出版社 *
王静安等: "《王静安医学新书》", 30 April 2008, 成都时代出版社 *
罗丽霞: "竹叶石膏汤新用", 《新中医》 *
陈长勋: "《中药药理学》", 31 January 2015, 上海科学技术出版 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107929433A (en) * 2017-12-19 2018-04-20 孙春苗 A kind of department of anesthesia is used for medicament of human body local anesthesia and preparation method thereof
CN108066649A (en) * 2018-01-09 2018-05-25 孙春苗 A kind of extract oral agent for treating rheumatoid arthritis and preparation method thereof

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