CN107441334A

CN107441334A - A kind of Chinese medicine composition for treating deficiency of both qi and yin with blood stasis type type II diabetes

Info

Publication number: CN107441334A
Application number: CN201710684634.7A
Authority: CN
Inventors: 孙素蓉
Original assignee: Chengdu Fengmi Biotechnology Co Ltd
Current assignee: Chengdu Fengmi Biotechnology Co Ltd
Priority date: 2017-08-11
Filing date: 2017-08-11
Publication date: 2017-12-08

Abstract

The invention belongs to field of traditional Chinese, purpose is a kind of Chinese medicine composition for treating deficiency of both qi and yin with blood stasis type type II diabetes provided according to the understanding mechanism of Chinese traditional treatment deficiency of both qi and yin with blood stasis type type II diabetes, and each component and its mass parts ratio of the Chinese medicine composition are as follows：50~150g of American Ginseng, 100~380g of the Radix Astragali, 100~180g of sealwort, 100~180g of radix polygonati officinalis, 90~180g of root of Chinese trichosanthes, 60~100g of rhizoma alismatis, 100~180g of the root of kudzu vine, 100~180g of giant knotweed, 15~35g of the coptis, 100~180g of reticulate millettia, 50~160g of the red sage root, 60~150g of raspberry, 100~380g of glibenclamide, medicine provided by the invention are a good Chinese prescriptions.

Description

A kind of Chinese medicine composition for treating deficiency of both qi and yin with blood stasis type type II diabetes

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of Chinese medicine for treating deficiency of both qi and yin with blood stasis type type II diabetes Composition, the field of the Chinese medicine composition particularly used for deficiency of both qi and yin with blood stasis type patients with NIDDM.

Background technology

Doctor thinks：Type II diabetes original name, more in the sequela of 35~40 years old, accounts for glycosuria Adult Onset's patients with type Ⅰ DM Patient more than 90%.The ability that insulin is produced in patients with NIDDM body not completely loses, some patient's body pancreas islet Element even produces excessive, but the action effect of insulin is poor, thus the insulin of patient's body be it is a kind of it is relative lack, can be with The secretion of internal insulin is stimulated by some oral drugs.But still there are some patients to need to use insulin therapy to the later stage.

So, it is this with regard to how to find a kind of Chinese medicine composition for imitating treatment deficiency of both qi and yin with blood stasis type type II diabetes The problem of art personnel are urgently to be resolved.

The content of the invention

With the continuous development of China's traditional Chinese medicine, on treatment deficiency of both qi and yin with blood stasis type type II diabetes, people by The advantages of gradually appreciating Chinese traditional treatment deficiency of both qi and yin with blood stasis type type II diabetes, and over the course for the treatment of good effect, it is quick, The advantages such as toxic side effect is small, for the present situation of existing western medical treatment rheumatoid, the purpose of the present invention is to be that providing one kind can have The Chinese medicine composition of effect treatment rheumatoid, to solve, deficiency of both qi and yin with blood stasis type patients with NIDDM is restorative early to ask Topic.The medicine is using common Chinese medicine as raw material, and by selecting rational medicine and mass parts ratio, it is cloudy can effectively to treat above-mentioned gas Two empty folder stasis of blood type type II diabetes.

To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：One kind is provided and treats deficiency of both qi and yin The Chinese medicine composition of stasis of blood type type II diabetes, it is characterised in that each component and its mass parts of the Chinese medicine composition are such as Shown in lower：

50~150g of American Ginseng, 100~380g of the Radix Astragali, 100~180g of sealwort, 100~180g of radix polygonati officinalis, 90~180g of root of Chinese trichosanthes, 60~100g of rhizoma alismatis, 100~180g of the root of kudzu vine, 100~180g of giant knotweed, 15~35g of the coptis, 100~180g of reticulate millettia, the red sage root 50~ 160g, 60~150g of raspberry, 100~380g of glibenclamide, auxiliary material：Appropriate starch.

A kind of Chinese medicine composition for treating deficiency of both qi and yin with blood stasis type type II diabetes, it is characterised in that the Chinese traditional medicine composition The each component and its mass parts of thing are than as follows：

58~130g of American Ginseng, 115~320g of the Radix Astragali, 115~150g of sealwort, 115~150g of radix polygonati officinalis, 100~150g of root of Chinese trichosanthes, 70~90g of rhizoma alismatis, 115~150g of the root of kudzu vine, 115~150g of giant knotweed, 18~32g of the coptis, 115~150g of reticulate millettia, the red sage root 58~ 130g, 70~130g of raspberry, 115~320g of glibenclamide, auxiliary material：Appropriate starch.

A kind of Chinese medicine composition for treating deficiency of both qi and yin with blood stasis type type II diabetes, it is characterised in that " the optimal side The each component and its mass parts of the Chinese medicine composition of case " are than as follows：

American Ginseng 115g, Radix Astragali 280g, sealwort 130g, radix polygonati officinalis 130g, root of Chinese trichosanthes 130g, rhizoma alismatis 80g, root of kudzu vine 130g, giant knotweed 130g, coptis 28g, reticulate millettia 130g, red sage root 115g, raspberry 115g, glibenclamide 280g, auxiliary material：Appropriate starch.

A kind of Chinese medicine composition for treating deficiency of both qi and yin with blood stasis type type II diabetes, it is characterised in that methods described includes Following steps are prepared：

A, in addition to starch, after above-mentioned raw materials Chinese medicine is picked impurity, dust and dried, it is ground into superfine end according to mass parts ratio and treats With；

B, the method for preparing Chinese medicine capsules according to tradition, after ground superfine myrrh thing and starch sieving, it is put into medicine device In be well mixed, then prepare filling into capsule（Total length is 23.3mm, 0.4~0.5g/ of medicinal powder capacity after its capsule is sealed Grain）, and then polish, sterilization, sealed packaging.

A kind of Chinese medicine composition for treating deficiency of both qi and yin with blood stasis type type II diabetes, it is characterised in that the instructions of taking For：By the capsule medicine prepared three times a day to take, once a dose in the morning, afternoon and evening, dosage 3g（6）/ time, before the meal partly Hour clothes（Taboo：1. serious renal insufficiency, diabetes mellitus DKA, stupor, insulin-dependent diabetics and Pregnant woman disables；2. please noting monitoring blood glucose during medication, and dosage is adjusted according to blood glucose）, while the conditioning that is careful in one's diet, one day three Meal wants rule, controls food-intake and dieting, to eat, treats 30~60 days less such as frying and containing sugared high, and blood glucose is controlled, and It is stable.

Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：

American Ginseng, nature and flavor：It is sweet, slight bitter, cold in nature, there is boosting qi and nourishing yin, the effect of promoting the production of body fluid of relieving inflammation or internal heat, for treating the cloudy specially fire of the deficiency of vital energy The diseases such as the tired tired, Heat Diabetes of prosperous, cough phlegm blood, abnormal heat, the dry cigarette of mouth be dry；

The Radix Astragali, nature and flavor：Sweet, tepor, there is the effect of invigorating qi for strengthening superficies, diuretic and maintain drug, apocenosis, expelling pus and promoting granulation, for treating the deficiency of vital energy Weak, anorexia and loose stool, the sinking of qi of middle-jiao, rush down prolapse of the anus for a long time, uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy oedema, ulcer is difficult to burst, burst for a long time and does not holds back, The diseases such as flaccidity of limbs due to deficiency of blood is yellow, Heat Diabetes, chronic rephrilis protinuria, diabetes；

Sealwort, nature and flavor：It is sweet, flat, have Yin nourishing and lung moistening, invigorate the spleen and benefit qi, Zishen fill fine the effect of, for treating deficiency of Yin overstrain cough, lung Cough caused by dryness is coughed, insufficiency of the spleen weak, few dry of food, quench one's thirst, deficiency of the kidney soreness and weakness of waist and knees, impotence and seminal emission, tinnitus mesh are dark, poliosis, physically weak win The diseases such as thin, wind favus disease；

Radix polygonati officinalis, nature and flavor：It is sweet, flat, have yin-nourishing, moisturize, relieving restlessness, the effect of quenching the thirst, for treat pyreticosis impairment of yin, cough polydipsia, Deficient fever, the paddy that disappears the easily disease such as famine, frequent urination；

Root of Chinese trichosanthes, nature and flavor：Sweet, slight bitter, cold nature, there is the effect of clearing heat and promoting fluid, moistening lung for removing phlegm, dense detumescence row, for controlling Treatment pyreticosis is thirsty, the diseases such as more drink, lung-heat type cough, sore swollen toxins of quenching one's thirst；

Rhizoma alismatis, nature and flavor：It is sweet, cold, there is the effect of diuresis, clearing away damp-heat, for treating difficult urination, oedema turgor, diarrhea urine Less, the disease such as phlegmatic vertigo, puckery pain of heat gonorrhea, high fat of blood；

The root of kudzu vine, nature and flavor：It is sweet, pungent, flat, have expelling pathogenic factors from muscles and skin bring down a fever, deliver examine, promote the production of body fluid to quench thirst, Shengyang Zhixie the effect of, for treating Fever caused by exogenous pathogens, rigidity of nape and headache, measles go out that not smooth, warm disease is thirsty, diabete, diarrhea, dysentery, hypertension, coronary heart disease etc. from the beginning of, rash Disease；

Giant knotweed, nature and flavor：Slight bitter, be slightly cold, have expelling wind and removing dampness, scattered stasis pain, it is relieving cough and reducing sputum the effect of, for treating joint numbness Bitterly, jaundice with damp-heat pathogen, Amenorrhea, abdominal mass, scald, injury from falling down, carbuncle sore tumefacting virus, coughing with a lot of sputum；

The coptis, nature and flavor：It is bitter, cold, have clearing heat-fire, eliminating dampness, removing toxic substances the effect of, enter for treating pyreticosis heresy the heart channel of Hang-Shaoyin high fever, Irritated, delirium or the hematemesis of the absurd row of the urgent blood of excess heat, the damp and hot feeling of stuffiness in chest, diarrhea, dysentery, the vexed insomnia of heart-fire hyperactivity, gastropyretic vomiting Or rapid digestion of food and polyorexia, irascibility red eye, swell pain and pathopyretic ulcer, serious case of furuncle septicemia, swelling and aching of gum, aphthae, Ting ear, swelling of vulva, hemorrhoid The diseases such as blood, eczema, scald；

Reticulate millettia, nature and flavor：It is bitter, sweet, warm, have enrich blood, invigorate blood circulation, dredging collateral the effect of, for treat irregular menstruation, blood deficiency chlorosis, Paralysis and numbness, arthralgia pain due to rheumatism；

The red sage root, nature and flavor：Bitter, cold nature, there is the effect of promoting blood circulation, menstruction regulating and pain relieving, nourishing blood and tranquilization, cool blood to disappear carbuncle, be used for Treat menoxenia, dysmenorrhoea, Amenorrhea, postpartum stasis of blood, trusted subordinate's pain, a lump in the abdomen causing distension and pain, the swelling and pain of hot numbness, traumatic injury, Heat enters the diseases such as ying blood, dysphoria, vexed insomnia, ulcerative carbuncle pyogenic infections；

Raspberry, nature and flavor：It is sweet, sour, warm, have kidney-nourishing, controlling nocturnal emission with astringent drugs, contracting urine the effect of, for treat enuresis with renal asthenia, frequent urination, Impotence and premature ejaculation, emission and spermatorrhea；

Glibenclamide, Non-Insulin Dependent Diabetes Mellitus patient is through diet and the still dissatisfied person of sports therapy glycemic control.Metabolism The good standard is controlled to be：Limosis vein blood sugar reaches 4.4-6.7mmol/L, and postprandial 2 hours blood glucose is 6.7-8.9mmol/L.It is right The good factor of su therapeutic responses has：1. age of onset is more than 40 years old；2. diabetic duration is less than 2 years；3. Normal-weight or It is fat；4. not used insulin or daily insulin dosage are less than 40u.In su, because GB blood sugar reducing functions are most strong, through dietetic treatment After appropriate physical exertion, fasting blood-glucose is advisable in 11mmol/L or so persons application.

Medicine of the present invention is the principle based on Chinese traditional treatment deficiency of both qi and yin with blood stasis type type II diabetes, from according to deficiency of both qi and yin The pathomechanism and pharmacological action for pressing from both sides stasis of blood type type II diabetes are thought：With regard to deficiency of both qi and yin with blood stasis type type II diabetes, institute of the present invention Each raw material herbal medicine efficacy in the medicine of offer is played altogether, has good therapeutic effect to above-mentioned disease.

Embodiment

A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of above-mentioned deficiency of both qi and yin with blood stasis type type II diabetes, The medicine effect prepared using the formula is good, quick, is a Chinese prescription treated both principal and secondary aspect of disease, is particularly suitable for Clinical practice. It is described in further detail with reference to the embodiment of the present invention：

Embodiment 1：

A kind of Chinese medicine composition for treating deficiency of both qi and yin with blood stasis type type II diabetes, it is characterised in that the Chinese medicine composition Each component and its mass parts are than as follows：

Embodiment 2：

American Ginseng 130g, Radix Astragali 320g, sealwort 150g, radix polygonati officinalis 150g, root of Chinese trichosanthes 150g, rhizoma alismatis 90g, root of kudzu vine 150g, giant knotweed 150g, coptis 32g, reticulate millettia 150g, red sage root 130g, raspberry 130g, glibenclamide 320g, auxiliary material：Appropriate starch.

Embodiment 3：

American Ginseng 150g, Radix Astragali 380g, sealwort 180g, radix polygonati officinalis 180g, root of Chinese trichosanthes 180g, rhizoma alismatis 100g, root of kudzu vine 180g, giant knotweed 180g, coptis 35g, reticulate millettia 180g, red sage root 160g, raspberry 150g, glibenclamide 380g, auxiliary material：Appropriate starch.

Model case

Through clinical conditions deficiency of both qi and yin with blood stasis type patients with NIDDM totally 1000, the age is 550 of more than 42 years old, Only 450 are less than 42 years old.Blood glucose is controlled and stablized in 1000 patients 530, it is effective 280, invalid 190.Total effective rate is up to 81%.

Claims

A kind of 1. Chinese medicine composition for treating deficiency of both qi and yin with blood stasis type type II diabetes, it is characterised in that the Chinese medicine composition Each component and its mass parts than as follows：

50~150g of American Ginseng, 100~380g of the Radix Astragali, 100~180g of sealwort, 100~180g of radix polygonati officinalis, 90~180g of root of Chinese trichosanthes, 60~100g of rhizoma alismatis, 100~180g of the root of kudzu vine, 100~180g of giant knotweed, 15~35g of the coptis, 100~180g of reticulate millettia, the red sage root 50~ 160g, 60~150g of raspberry, 100~380g of glibenclamide, auxiliary material：Appropriate starch.
2. the Chinese medicine composition for the treatment of deficiency of both qi and yin with blood stasis type type II diabetes according to claim 1, it is characterised in that The each component and its mass parts of the Chinese medicine composition are than as follows：

58~130g of American Ginseng, 115~320g of the Radix Astragali, 115~150g of sealwort, 115~150g of radix polygonati officinalis, 100~150g of root of Chinese trichosanthes, 70~90g of rhizoma alismatis, 115~150g of the root of kudzu vine, 115~150g of giant knotweed, 18~32g of the coptis, 115~150g of reticulate millettia, the red sage root 58~ 130g, 70~130g of raspberry, 115~320g of glibenclamide, auxiliary material：Appropriate starch.
3. the Chinese medicine composition of the treatment deficiency of both qi and yin with blood stasis type type II diabetes according to claim 1 to 2, its feature exist In each component and its mass parts of the Chinese medicine composition are than as follows：

American Ginseng 115g, Radix Astragali 280g, sealwort 130g, radix polygonati officinalis 130g, root of Chinese trichosanthes 130g, rhizoma alismatis 80g, root of kudzu vine 130g, giant knotweed 130g, coptis 28g, reticulate millettia 130g, red sage root 115g, raspberry 115g, glibenclamide 280g, auxiliary material：Appropriate starch.