CN107423347B - A kind of Chinese medicine preparation analysis of effective component method and terminal device - Google Patents
A kind of Chinese medicine preparation analysis of effective component method and terminal device Download PDFInfo
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- G06F16/00—Information retrieval; Database structures therefor; File system structures therefor
- G06F16/30—Information retrieval; Database structures therefor; File system structures therefor of unstructured textual data
- G06F16/31—Indexing; Data structures therefor; Storage structures
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- G06F16/319—Inverted lists
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Abstract
The present invention discloses a kind of Chinese medicine preparation analysis of effective component method and terminal device, it is related to Pharmaceutical Analysis technical field, to shorten the time for quickly analyzing wherein effective component from numerous Chinese medicine preparations, the Chinese medicine preparation analysis of effective component method filters out the m piece patent document for treating the disease according to disease category from patent database, and default n kind Chinese traditional medicine composition, by calculating the different degree of every kind of Chinese traditional medicine composition, the maximum Chinese traditional medicine composition of different degree is then selected as the effective component for treating the disease.The terminal device that above-mentioned technical proposal is mentioned is for executing Chinese medicine preparation analysis of effective component method.Chinese medicine preparation analysis of effective component method provided by the invention is in Pharmaceutical Analysis.
Description
Technical field
The present invention relates to Pharmaceutical Analysis fields more particularly to a kind of Chinese medicine preparation analysis of effective component method and terminal to set
It is standby.
Background technique
Chinese medicine is that a kind of medicine with Chinese tradition characteristic is regarded as human body using yin-yang and five elements as theoretical basis
It is the entity of gas, shape, mind, by prestige, hears, asks, cuts, the method that ginseng is closed in the four methods of diagnosis seeks the cause of disease, characteristic of disease, sick position, analyzes the interpretation of the cause, onset and process of an illness
And in human body the vital organs of the human body, channels and collaterals joint, qi-blood-body fluid variation, judge pathogenic and vital contention, and then obtain name of disease, conclusion is come to testify
Type, with diagnosis and treatment principle, formulate " sweat, spit, under and temperature, it is clear, mend, disappear " etc. therapies, using Chinese medicine, acupuncture, massage, press
It rubs, cupping, the qigong, a variety for the treatment of means such as dietotherapy, so that human body is reached yin-yang and reconcile and rehabilitation.
When medicine treatment disease in use, different doctors is not quite similar to the Chinese medicine preparation that same patient outputs.To control
For the Chinese medicine preparation for treating lung cancer, the Chinese medicine preparation that can be found in patent document just has as many as tens kinds, such as the Chinese medicine having
It include " Radix Glehniae, Radix Ophiopogonis, oldenlandia diffusa, edible tulip, radix ranunculi ternati fry cattail pollen " in formula, include in some formulas " ginseng,
Radix Astragali, oldenlandia diffusa, radix ranunculi ternati, safflower, Typhonium flagelliforme (Lodd.) Blume powder, Moschus, lobelia chinensis, curcuma zedoary, Chinese trumpet creeper, rhizoma cyperi, peach kernel, precognition
Son, gecko, cordyceps sinensis, ganoderma spove powder ", there are also include " edible tulip, Radix Astragali, green tea, propolis, sand in some formulas
Spine, centipede, pheretima, fritillaria thunbergii, green onion, calamus, Radix Angelicae Sinensis, Golden Larch Bark ", there are also the Chinese medicine preparations of other treatment lung cancer certainly, herein
Just do not listing.The component that can be seen that every kind of Chinese medicine preparation for the treatment of lung cancer from these listed Chinese medicine preparations has
As many as 6-15 kind, if analyzing effective component therein by testing, when can make the analysis of effective component of Chinese medicine preparation
Between it is too long.
Therefore, how from treat certain disease numerous Chinese medicine preparations in quickly analyze effective component therein, to mention
The medication accuracy of high Chinese medicine doctor is the present technical issues that need to address.
Summary of the invention
The purpose of the present invention is to provide a kind of Chinese medicine preparation effective components to determine method and terminal device, is comformed with shortening
The time of wherein effective component is quickly analyzed in more Chinese medicine preparations, to improve the medication accuracy of Chinese medicine doctor.
To achieve the goals above, the invention provides the following technical scheme:
A kind of Chinese medicine preparation analysis of effective component method, it is suitable for executing in terminal device, the Chinese medicine preparation is effective
Component analyzing method includes:
S1: disease category is obtained, filters out the m piece patent for treating the disease from patent database according to disease category
Document, according to the n kind Chinese traditional medicine composition of disease described in disease category predetermined treatment；Every kind of Chinese traditional medicine composition includes s kind Chinese medicine group
Point；Wherein, 2≤s≤n；
S2: the sequential labeling r=1 of Chinese traditional medicine composition is set；
S3: it according to the traditional Chinese medicinal components in m patent documents and r kind Chinese traditional medicine composition, obtains comprising r kind Chinese traditional medicine composition
Patent document number Cr, patent document number S comprising the 1st kind of traditional Chinese medicinal components in r kind Chinese traditional medicine compositionr1And include r kind Chinese medicine
The patent document number S of s kind traditional Chinese medicinal components in combinationrs；
S4: compare the patent document number S comprising the 1st kind of traditional Chinese medicinal components in r kind Chinese traditional medicine compositionr1To including r kind Chinese medicine
The patent document number S of s kind traditional Chinese medicinal components in combinationrs, obtain the single traditional Chinese medicinal components patent document number of r kind Chinese traditional medicine composition most
Big value Srmax；
S5: according to the patent document number C comprising r kind Chinese traditional medicine compositionrIt is special with the single traditional Chinese medicinal components of r kind Chinese traditional medicine composition
Sharp document number maximum value Srmax, obtain the different degree Z of r kind Chinese traditional medicine compositionr；
S6: setting the sequential labeling r=k of Chinese traditional medicine composition, as r≤n, executes S3；As r > n, S7 is executed, wherein during k is
The setting number of the sequential labeling of medicine combination；
S7: the maximum Chinese traditional medicine composition of different degree is selected from the different degree of n kind Chinese traditional medicine composition as the treatment disease
Effective component.
Compared with prior art, in Chinese medicine preparation analysis of effective component method provided by the invention, according to disease category from
Patent database filters out the m kind Chinese medicine preparation for the treatment of disease, while default n kind Chinese traditional medicine composition, then according to m patent documents
The patent document number comprising current Chinese traditional medicine composition is obtained with the traditional Chinese medicinal components in current Chinese traditional medicine composition and comprising current Chinese medicine group
The patent document of the 1st kind of medicine component counts to the patent document number of s kind medicine component in conjunction, further to compare comprising current Chinese medicine
The patent document of the 1st kind of traditional Chinese medicinal components counts to the patent document number comprising s kind traditional Chinese medicinal components in current Chinese traditional medicine composition in combination,
The corresponding single traditional Chinese medicinal components patent document number maximum value of current Chinese traditional medicine composition is obtained, basis includes current kind of Chinese traditional medicine composition in this way
Patent document number and current Chinese traditional medicine composition single traditional Chinese medicinal components patent document number maximum value, current Chinese medicine can be obtained
Combined different degree is based on this, by the different degree for comparing different Chinese traditional medicine compositions, so that it may which drug needed for judging disease is most
Good effective component, by the analytic process it is found that this analysis method can by the realization of automation, be greatly saved from
The time of wherein effective component is quickly analyzed in numerous more Chinese medicine preparations, to improve the medication accuracy of Chinese medicine doctor.
The present invention also provides a kind of terminal device, which includes the memory and processor communicated with each other；Institute
Memory is stated for storing a plurality of instruction to realize Chinese medicine preparation analysis of effective component method；The a plurality of instruction is added by processor
It carries and executes:
Disease category is obtained, filters out the m piece patent text for treating the disease from patent database according to disease category
It offers, according to the n kind Chinese traditional medicine composition of disease described in disease category predetermined treatment；Every kind of Chinese traditional medicine composition includes s kind traditional Chinese medicinal components；
Wherein, 2≤s≤n；
The m piece patent document for treating the disease is filtered out from patent database according to disease category；
Set the sequential labeling r=k of Chinese traditional medicine composition；As r≤n, the number resolution unit operation is controlled, when r > n, control
Make the effective component judging unit operation；Wherein, k is the setting number of the sequential labeling of Chinese traditional medicine composition；
According to the traditional Chinese medicinal components in m patent documents and r kind Chinese traditional medicine composition, obtain special comprising r kind Chinese traditional medicine composition
Sharp document number Cr, patent document number S comprising the 1st kind of traditional Chinese medicinal components in r kind Chinese traditional medicine compositionr1And include r kind Chinese medicine group
The patent document number S of s kind traditional Chinese medicinal components in conjunctionrs；
Compare the patent document number S comprising the 1st kind of traditional Chinese medicinal components in r kind Chinese traditional medicine compositionr1To including r kind Chinese traditional medicine composition
In s kind traditional Chinese medicinal components patent document number Srs, obtain the single traditional Chinese medicinal components patent document number maximum value of r kind Chinese traditional medicine composition
Srmax；
According to the patent document number C comprising r kind Chinese traditional medicine compositionrWith the single traditional Chinese medicinal components patent of r kind Chinese traditional medicine composition
Document number maximum value Srmax, obtain the different degree Z of r kind Chinese traditional medicine compositionr；
The maximum Chinese traditional medicine composition of different degree is selected from the different degree of n kind Chinese traditional medicine composition as the effective of the treatment disease
Ingredient.
Compared with prior art, the present invention also provides terminal device beneficial effect and above-mentioned technical proposal provide institute
The beneficial effect for stating Chinese medicine preparation analysis of effective component method is identical, and this will not be repeated here.
Detailed description of the invention
The drawings described herein are used to provide a further understanding of the present invention, constitutes a part of the invention, this hair
Bright illustrative embodiments and their description are used to explain the present invention, and are not constituted improper limitations of the present invention.In the accompanying drawings:
Fig. 1 is Chinese medicine preparation analysis of effective component method flow diagram one provided in an embodiment of the present invention；
Fig. 2 is Chinese medicine preparation analysis of effective component method flow diagram two provided in an embodiment of the present invention；
Fig. 3 is Chinese medicine preparation analysis of effective component method flow diagram three provided in an embodiment of the present invention；
Fig. 4 is the structural block diagram one of Chinese medicine preparation analysis of effective component device provided in an embodiment of the present invention；
Fig. 5 is the structural block diagram two of Chinese medicine preparation analysis of effective component device provided in an embodiment of the present invention；
Fig. 6 is the structural block diagram three of Chinese medicine preparation analysis of effective component device provided in an embodiment of the present invention；
Fig. 7 is the structural schematic diagram of terminal device provided in an embodiment of the present invention.
Specific embodiment
The technical solution that embodiment provides in order to further illustrate the present invention, is retouched in detail with reference to the accompanying drawings of the specification
It states.
Referring to Fig. 1, Chinese medicine preparation analysis of effective component method provided in an embodiment of the present invention, suitable for terminal device
It executes, which specifically comprises the following steps:
S1: disease category is obtained, filters out the m piece patent for treating the disease from patent database according to disease category
Document, according to the n kind Chinese traditional medicine composition of disease described in disease category predetermined treatment；Every kind of Chinese traditional medicine composition includes s kind Chinese medicine group
Point；Wherein, 2≤s≤n；
S2: the sequential labeling r=1 of Chinese traditional medicine composition is set；
S3: it according to the traditional Chinese medicinal components in m patent documents and r kind Chinese traditional medicine composition, obtains comprising r kind Chinese traditional medicine composition
Patent document number Cr, patent document number S comprising the 1st kind of traditional Chinese medicinal components in r kind Chinese traditional medicine compositionr1And include r kind Chinese medicine
The patent document number S of s kind traditional Chinese medicinal components in combinationrs；
S4: compare the patent document number S comprising the 1st kind of traditional Chinese medicinal components in r kind Chinese traditional medicine compositionr1To including r kind Chinese medicine
The patent document number S of s kind traditional Chinese medicinal components in combinationrs, obtain the single traditional Chinese medicinal components patent document number of r kind Chinese traditional medicine composition most
Big value Srmax；
S5: according to the patent document number C comprising r kind Chinese traditional medicine compositionrIt is special with the single traditional Chinese medicinal components of r kind Chinese traditional medicine composition
Sharp document number maximum value Srmax, obtain the different degree Z of r kind Chinese traditional medicine compositionr；The different degree Z of r kind Chinese traditional medicine compositionrCalculating it is public
Formula are as follows:
From the different degree Z of r kind Chinese traditional medicine compositionrCalculation formula it can be seen that the patent document number C comprising Chinese traditional medicine compositionr
Number it is more, show that the different degree of Chinese traditional medicine composition is higher, and single traditional Chinese medicinal components patent document number maximum value SrmaxIt is bigger, table
The different degree of bright Chinese traditional medicine composition is smaller, and (such as water possibly is present in many Chinese medicine preparations, but the actual therapeutic effect of water is not
Greatly).
S6: setting the sequential labeling r=k of Chinese traditional medicine composition, as r≤n, executes S3；As r > n, S7 is executed, wherein during k is
The setting number of the sequential labeling of medicine combination；
S7: the maximum Chinese traditional medicine composition of different degree is selected from the different degree of n kind Chinese traditional medicine composition as the treatment disease
Effective component.
The specific steps of the Chinese medicine preparation analysis of effective component method provided through this embodiment are it is found that if necessary to determine
The best available ingredient for treating certain disease is matched according to disease category from the m kind Chinese medicine that patent database filters out treatment disease
Then side, while default n kind Chinese traditional medicine composition are included according to the traditional Chinese medicinal components in m patent documents and current Chinese traditional medicine composition
The current patent document number of Chinese traditional medicine composition and the patent document comprising the 1st kind of medicine component in current Chinese traditional medicine composition count to s kind
The patent document number of medicine component is counted to further comparing the patent document comprising the 1st kind of traditional Chinese medicinal components in current Chinese traditional medicine composition
Patent document number comprising s kind traditional Chinese medicinal components in current Chinese traditional medicine composition obtains the corresponding single Chinese medicine group of current Chinese traditional medicine composition
Divide patent document number maximum value, in this way according to the patent document number C comprising current kind of Chinese traditional medicine compositionrWith single traditional Chinese medicinal components patent
Document number maximum value, can obtain the different degree of current Chinese traditional medicine composition, be based on this, by the weight for comparing different Chinese traditional medicine compositions
It spends, so that it may the best available ingredient of drug needed for judging disease, by the analytic process it is found that this analysis method can
To be greatly saved the time for quickly analyzing wherein effective component in the more Chinese medicine preparation of comforming by the realization of automation,
To improve the medication accuracy of Chinese medicine doctor.
In addition, Chinese medicine preparation analysis of effective component method provided in this embodiment is only needed using patent database as data
Source being acquired, and since patent database belongs to the database to public, can not have as long as through the network equipment in this way
Patent database is accessed in the case where there are any restrictions, this greatly facilitates Chinese medicine preparation analysis of effective component method.
Illustratively, by taking this disease type of lung cancer as an example, the traditional Chinese medicinal components of predetermined treatment lung cancer include Radix Astragali, Radix Codonopsis,
These default traditional Chinese medicinal components are carried out any combination three times, obtain four kinds of Chinese traditional medicine compositions, respectively by oldenlandia diffusa, ginseng
Are as follows:
The first Chinese traditional medicine composition: Radix Astragali and oldenlandia diffusa；Second of Chinese traditional medicine composition: ginseng and oldenlandia diffusa the third
Chinese traditional medicine composition: Radix Astragali and ginseng；4th kind of Chinese traditional medicine composition: Radix Codonopsis and ginseng.
Each traditional Chinese medicinal components in four kinds of Chinese traditional medicine compositions are retrieved in wisdom bud patent database, search result
It is as follows:
In the first Chinese traditional medicine composition: retrieving the patent document that the Chinese medicine preparation for treating lung cancer includes Radix Astragali has 286
；Retrieving the patent document that the Chinese medicine preparation for treating lung cancer includes oldenlandia diffusa has 175；It retrieves for treating
The Chinese medicine preparation of lung cancer includes that the patent document of Radix Astragali and oldenlandia diffusa has 83 simultaneously；
The different degree of the first Chinese traditional medicine composition
Wherein, C1=83, S11=286, S12=175, S1max=286.
In second of Chinese traditional medicine composition: retrieving the patent document that the Chinese medicine preparation for treating lung cancer includes ginseng has 168
；Retrieving the patent document that the Chinese medicine preparation for treating lung cancer includes oldenlandia diffusa has 175；It retrieves for treating
The Chinese medicine preparation of lung cancer includes that the patent document of ginseng and oldenlandia diffusa has 44 simultaneously；
The different degree of second of Chinese traditional medicine composition
Wherein, C2=44, S21=168, S22=175, S2max=175.
In the third Chinese traditional medicine composition: retrieving the patent document that the Chinese medicine preparation for treating lung cancer includes Radix Astragali has 286
；Retrieving the patent document that the Chinese medicine preparation for treating lung cancer includes ginseng has 168；It retrieves for treating lung cancer
Chinese medicine preparation includes that the patent document of Radix Astragali and ginseng has 91 simultaneously；
The different degree of the third Chinese traditional medicine composition
Wherein, C3=91, S31=286, S32=168, S3max=286.
In 4th kind of Chinese traditional medicine composition: retrieving the patent document that the Chinese medicine preparation for treating lung cancer includes Radix Codonopsis has 96
；Retrieving the patent document that the Chinese medicine preparation for treating lung cancer includes ginseng has 168；It retrieves for treating lung cancer
Chinese medicine preparation includes that the patent document of ginseng and Radix Codonopsis has 18 simultaneously；
The different degree of 4th kind of Chinese traditional medicine composition
Wherein, C4=18, S41=96, S42=168, S4max=168.
It obtains, the different degree highest of the third Chinese traditional medicine composition, illustrates in the Chinese medicine preparation for the treatment of lung cancer from result above,
Radix Astragali and ginseng are used in conjunction with higher to the validity for curing lung cancer.
It should be noted that including: according to disease according to the method for the n kind Chinese traditional medicine composition of disease category predetermined treatment disease
Classification presets the traditional Chinese medicinal components of a variety for the treatment of diseases, carries out the combination of n kind to the traditional Chinese medicinal components of a variety for the treatment of diseases, obtains n
Kind Chinese traditional medicine composition, the quantity of the traditional Chinese medicinal components of n kind Chinese traditional medicine composition may be the same or different.
And in view of not only containing corresponding traditional Chinese medicinal components in patent document, also containing some other unrelated with traditional Chinese medicinal components
Content so that matching from determining that the process comprising traditional Chinese medicinal components in Chinese traditional medicine composition is slow in patent document in order to improve Chinese medicine
Square analysis of effective component speed, as shown in Fig. 2, above-mentioned S3 the following steps are included:
S31: m patent documents are segmented, the word segmentation result of m patent documents is obtained；
S32: according to the traditional Chinese medicinal components of preset a variety for the treatment of diseases, the row of falling is established to the word segmentation result of m patent documents
Index obtains participle inverted index file；
Illustratively, it segments in every participle inverted index of inverted index file and contains traditional Chinese medicinal components information, and
The corresponding patent document of traditional Chinese medicinal components information；
S33: various traditional Chinese medicinal components in r kind Chinese traditional medicine composition are retrieved from participle inverted index file, are obtained comprising r kind
The patent document number C of Chinese traditional medicine compositionr, patent document number S comprising the 1st kind of traditional Chinese medicinal components in r kind Chinese traditional medicine compositionr1And comprising
The patent document number S of s kind traditional Chinese medicinal components in r kind Chinese traditional medicine compositionrs。
By the description to above-mentioned S3 it is found that since the present embodiment is by segmenting m patent documents, so that m
Content in patent document is divided into short and small vocabulary, and according to the traditional Chinese medicinal components of preset a variety for the treatment of diseases, specially to m
The word segmentation result of sharp document establishes inverted index, to obtain participle inverted index file, in this way from participle inverted index file
When retrieving various traditional Chinese medicinal components in r kind Chinese traditional medicine composition, cracking can retrieve in each patent document whether contain r kind
Traditional Chinese medicinal components in Chinese traditional medicine composition, without browsing entire chapter patent document；In addition, due to according to preset a variety for the treatment of diseases
The traditional Chinese medicinal components of disease, establish inverted index to the word segmentation result of m patent documents, to obtain participle inverted index file, not only
Participle inverted index file can be retrieved whether containing the traditional Chinese medicinal components in r kind Chinese traditional medicine composition, and in participle inverted index
When in file containing the traditional Chinese medicinal components in r kind Chinese traditional medicine composition, the traditional Chinese medicinal components institute in contained r kind Chinese traditional medicine composition is determined
Corresponding patent document, to be accurately obtained the patent document number C comprising r kind Chinese traditional medicine compositionr, include r kind Chinese traditional medicine composition
In the 1st kind of traditional Chinese medicinal components patent document number Sr1And the patent document number comprising s kind traditional Chinese medicinal components in r kind Chinese traditional medicine composition
Srs。
Specifically, retrieving various traditional Chinese medicinal components in r kind Chinese traditional medicine composition to from participle inverted index file in conjunction with attached drawing
Detailed process be described.
As shown in figure 3, retrieving the specific step of various traditional Chinese medicinal components in r kind Chinese traditional medicine composition from participle inverted index file
Suddenly include:
S331: sequential labeling f=1 of the setting traditional Chinese medicinal components in r kind Chinese traditional medicine composition；
S332: the patent text comprising f kind traditional Chinese medicinal components in r kind Chinese medicine group is retrieved from participle inverted index file
It offers, obtains the f kind traditional Chinese medicinal components patent document set I of r kind Chinese traditional medicine compositionrf；Wherein, 1≤f≤t；
S333: according to the f kind traditional Chinese medicinal components patent document set I of r kind Chinese traditional medicine compositionfMiddle number of elements, is wrapped
Patent document number S containing f kind traditional Chinese medicinal components in r kind Chinese traditional medicine compositionrf；
S334: sequential labeling f=k ' of the setting traditional Chinese medicinal components in r kind Chinese traditional medicine composition executes S332 as f≤s；Work as f
> s executes S335；Wherein, k ' is the setting number of sequential labeling of the traditional Chinese medicinal components in r kind Chinese traditional medicine composition；
S335: to the 1st kind of traditional Chinese medicinal components patent document set I of r kind Chinese traditional medicine compositionr1To the s of r kind Chinese traditional medicine composition
Kind traditional Chinese medicinal components patent document set IrsIntersection processing is carried out, the Searches of Patent Literature comprising r kind Chinese traditional medicine composition is obtained and hands over
Collection；
S336: it according to number of elements in the Searches of Patent Literature intersection comprising r kind Chinese traditional medicine composition, obtains comprising r kind
The patent document number C of Chinese traditional medicine compositionr。
As shown in Figure 1 and Figure 4, the embodiment of the invention provides a kind of Chinese medicine preparation analysis of effective component device, the Chinese medicines
Being formulated analysis of effective component device is a kind of virtual software service, specifically includes data capture unit 1, literature search unit
2, number resolution unit 3, take big processing unit 4, different degree computing unit 5, effective component judging unit 6 and loop control list
Member 7；
The output end of data capture unit 1 is connect with the input terminal of literature search unit 2, the output of data capture unit 1
The output end of end and literature search unit 2 is connect with the input terminal of number resolution unit 3 respectively, the output of number resolution unit 3
End is connect with the input terminal of the input terminal and different degree computing unit 5 that take big processing unit 4 respectively, takes the defeated of big processing unit 4
Outlet is connect with the input terminal of different degree computing unit 5, and the output end of different degree computing unit 5 is defeated with loop control unit 7
Enter end connection, the output end of loop control unit 7 respectively with the input terminal of number resolution unit 3 and effective component judging unit 6
Input terminal connection；
Data capture unit 1 is for obtaining disease category；According to the n kind Chinese medicine group of disease described in disease category predetermined treatment
It closes；Every kind of Chinese traditional medicine composition includes s kind traditional Chinese medicinal components；Wherein, 2≤s≤n；
Literature search unit 2 is used to filter out the m piece for treating the disease from patent database according to disease category special
Sharp document；
Loop control unit 7 is used to set the sequential labeling r=k of Chinese traditional medicine composition；As r≤n, number resolution unit 3 is controlled
Operation controls effective component judging unit 6 and runs as r > n；Wherein, k is the setting number of the sequential labeling of Chinese traditional medicine composition；
Number resolution unit 3 is used for
The patent document number C of r kind Chinese traditional medicine compositionr, patent document number S comprising the 1st kind of traditional Chinese medicinal components in r kind Chinese traditional medicine compositionr1With
And the patent document number S comprising s kind traditional Chinese medicinal components in r kind Chinese traditional medicine compositionrs；
Take big processing unit 4 for comparing the patent document number S comprising the 1st kind of traditional Chinese medicinal components in r kind Chinese traditional medicine compositionr1It arrives
Patent document number S comprising s kind traditional Chinese medicinal components in r kind Chinese traditional medicine compositionrs, obtain the single Chinese medicine group of r kind Chinese traditional medicine composition
Divide patent document number maximum value Srmax；
Different degree computing unit 5 is used for according to the patent document number C comprising r kind Chinese traditional medicine compositionrWith r kind Chinese traditional medicine composition
Single traditional Chinese medicinal components patent document number maximum value Srmax, obtain the different degree Z of r kind Chinese traditional medicine compositionr；
Effective component judging unit 6 from the different degree of n kind Chinese traditional medicine composition for selecting the maximum Chinese traditional medicine composition of different degree
As the effective component for treating the disease.
Have to Chinese medicine preparation analysis of effective component device provided in this embodiment to Chinese medicine preparation below with reference to Fig. 1 and Fig. 4
Imitate ingredient has analytic process.
S100: data capture unit 1 obtains disease category；According to the n kind Chinese medicine of disease described in disease category predetermined treatment
Combination；Every kind of Chinese traditional medicine composition includes s kind traditional Chinese medicinal components；Wherein, 2≤s≤n；
Literature search unit 2 filters out the m piece patent text for treating the disease according to disease category from patent database
It offers,
S200: the sequential labeling r=1 of the setting Chinese traditional medicine composition of loop control unit 7；
S300: number resolution unit 3 included according to the traditional Chinese medicinal components in m patent documents and r kind Chinese traditional medicine composition
The patent document number C of r kind Chinese traditional medicine compositionr, patent document number S comprising the 1st kind of traditional Chinese medicinal components in r kind Chinese traditional medicine compositionr1With
And the patent document number S comprising s kind traditional Chinese medicinal components in r kind Chinese traditional medicine compositionrs；
S400: big processing unit 4 is taken to compare the patent document number S comprising the 1st kind of traditional Chinese medicinal components in r kind Chinese traditional medicine compositionr1
The patent document number S of s kind traditional Chinese medicinal components in comprising r kind Chinese traditional medicine compositionrs, obtain single traditional Chinese medicinal components patent document number most
Big value Srmax；
S500: different degree computing unit 5 is according to the patent document number C comprising r kind Chinese traditional medicine compositionrWith single traditional Chinese medicinal components
Patent document number maximum value Srmax, obtain the different degree Z of r kind Chinese traditional medicine compositionr；
S600: loop control unit 7 sets the sequential labeling r=k of Chinese traditional medicine composition, as r≤n, executes S300, as r > n,
Execute S700；Wherein, k is the setting number of the sequential labeling of Chinese traditional medicine composition；
S700: effective component judging unit 6 selects the maximum Chinese traditional medicine composition of different degree from the different degree of n kind Chinese traditional medicine composition
Effective component as treatment disease.
Compared with prior art, the beneficial effect of Chinese medicine preparation analysis of effective component device provided in an embodiment of the present invention with
The beneficial effect for the Chinese medicine preparation analysis of effective component method that above-mentioned technical proposal provides is identical, and this will not be repeated here.
It should be noted that as shown in figure 5, data capture unit 1 includes disease type analysis module 11 and pharmaceutical composition
Determining module 12；The output end of disease type analysis module 11 is examined with the input terminal of pharmaceutical composition determining module 12 and document respectively
The input terminal of cable elements 2 connects；The output end of pharmaceutical composition determining module 12 is connect with the input terminal of number resolution unit 3；
When it is implemented, disease type analysis module 11 is used to obtain disease information, according to disease information to disease information
Determine disease type；Pharmaceutical composition determining module 12 is used to preset the Chinese medicine group of a variety for the treatment of diseases according to disease category
Point, n times combination is carried out to the traditional Chinese medicinal components of a variety for the treatment of diseases, obtains n kind Chinese traditional medicine composition.
Specifically, as shown in Figure 3 and Figure 6, above-mentioned number resolution unit 3 include word segmentation module 31, index establish module 32,
Traditional Chinese medicinal components retrieval module 33, the first elemental analysis module 34, intersection module 35 and second element analysis module 36；
The output end of literature search unit 2 is connect with the input terminal of word segmentation module 31, the output end and medicine of word segmentation module 31
The input terminal that the output end of object combination determining module 12 establishes module 32 with index respectively is connect, and index establishes the output of module 32
The output end of end and pharmaceutical composition determining module 12 is connect with the input terminal of traditional Chinese medicinal components retrieval module 33 respectively, traditional Chinese medicinal components inspection
The output end of rope module 33 is connect with the input terminal of the input terminal of the first elemental analysis module 34 and intersection module 35 respectively, is handed over
The output end of collectionization module 35 is connect with the input terminal of second element analysis module 36；The output end of first elemental analysis module 34
It is connect with the input terminal of big processing unit 4 is taken, the input of the output end and different degree computing unit 5 of second element analysis module 36
End connection, the input terminal of loop control unit 7 are also connect with the output end of the first elemental analysis module 34, loop control unit 7
Output end also connect respectively with the input terminal of the input terminal of traditional Chinese medicinal components retrieval module 33 and intersection module 35；
Word segmentation module 31 obtains the word segmentation result of m patent documents for segmenting to m patent documents；
Index establishes module 32 for the traditional Chinese medicinal components according to preset a variety for the treatment of diseases, divides m patent documents
Word result establishes inverted index, obtains participle inverted index file；
Loop control unit 7 is for setting sequential labeling f=k ' of the traditional Chinese medicinal components in r kind Chinese traditional medicine composition；Wherein, k '
For the setting number of sequential labeling of the traditional Chinese medicinal components in r kind Chinese traditional medicine composition；
As r≤k or f≤s, control the traditional Chinese medicinal components retrieval module operation, as f > s, control the intersection module and
It is described that big processing unit is taken to run；
Traditional Chinese medicinal components retrieval module 33 is used to from participle inverted index file retrieve comprising f in r kind Chinese medicine group
The patent document of kind traditional Chinese medicinal components, obtains the f kind traditional Chinese medicinal components patent document set I of r kind Chinese traditional medicine compositionrf；Wherein, 1≤f
≤s；
First elemental analysis module 34 is used for the f kind traditional Chinese medicinal components patent document set I according to r kind Chinese traditional medicine compositionf
Middle number of elements obtains the patent document number S comprising f kind traditional Chinese medicinal components in r kind Chinese traditional medicine compositionrf；
Intersection module 35 is used for the 1st kind of traditional Chinese medicinal components patent document set I to r kind Chinese traditional medicine compositionr1Into r kind
The s kind traditional Chinese medicinal components patent document set I of medicine combinationrsIntersection processing is carried out, the patent comprising r kind Chinese traditional medicine composition is obtained
Literature search intersection；
Second element analysis module 36 is used for according to prime number first in the Searches of Patent Literature intersection comprising r kind Chinese traditional medicine composition
Amount, obtains the patent document number C comprising r kind Chinese traditional medicine compositionr。
When it is implemented, can realize the function of number resolution unit 3 in the present embodiment by step in detail below.
S301: word segmentation module 31 segments m patent documents, obtains the word segmentation result of m patent documents；
S302: index establishes module 32 for the traditional Chinese medicinal components according to preset a variety for the treatment of diseases, to m patent documents
Word segmentation result establish inverted index, obtain participle inverted index file；
S303: loop control unit 7 sets sequential labeling f=1 of the traditional Chinese medicinal components in r kind Chinese traditional medicine composition；
S304: traditional Chinese medicinal components retrieval module 33 is retrieved from participle inverted index file comprising f in r kind Chinese medicine group
The patent document of kind traditional Chinese medicinal components, obtains the f kind traditional Chinese medicinal components patent document set I of r kind Chinese traditional medicine compositionrf；Wherein, 1≤f
≤s；
S305: the first elemental analysis module 34 is according to the f kind traditional Chinese medicinal components patent document set I of r kind Chinese traditional medicine compositionf
Middle number of elements obtains the patent document number S comprising f kind traditional Chinese medicinal components in r kind Chinese traditional medicine compositionrf；
S306: loop control unit 7 sets sequential labeling f=k ' of the traditional Chinese medicinal components in r kind Chinese traditional medicine composition；When f≤
S executes S304, as f > s, executes S307 and S400；Wherein, k ' is sequential labeling of the traditional Chinese medicinal components in r kind Chinese traditional medicine composition
Setting number；
S307: 1st kind traditional Chinese medicinal components patent document set I of the intersection module 35 to r kind Chinese traditional medicine compositionr1To r kind
The s kind traditional Chinese medicinal components patent document set I of Chinese traditional medicine compositionrsIntersection processing is carried out, is obtained special comprising r kind Chinese traditional medicine composition
Sharp literature search intersection；
S308: second element analysis module 36 is according to element in the Searches of Patent Literature intersection comprising r kind Chinese traditional medicine composition
Quantity obtains the patent document number C comprising r kind Chinese traditional medicine compositionr。
In addition, when the output end of loop control unit 7 is connect with the input terminal of traditional Chinese medicinal components retrieval module 33, above-mentioned reality
The S600 in example is applied after the sequential labeling r=k of setting Chinese traditional medicine composition, if r≤n, can use traditional Chinese medicinal components retrieval module
Each traditional Chinese medicinal components are retrieved in 33 pairs of next Chinese traditional medicine compositions.
Referring to Fig. 7, the embodiment of the invention also provides a kind of terminal device, its essence is a kind of entity hardware device,
The memory 100 and processor 200 communicated with each other is specifically included, further includes connection memory and processing in certain terminal device
The bus 300 of device, to realize being in communication with each other for memory 100 and processor 200；Wherein, memory 100 is for storing a plurality of finger
It enables to realize Chinese medicine preparation analysis of effective component method；A plurality of instruction is loaded and is executed by processor 200:
Disease category is obtained, filters out the m piece patent text for treating the disease from patent database according to disease category
It offers, according to the n kind Chinese traditional medicine composition of disease described in disease category predetermined treatment；Every kind of Chinese traditional medicine composition includes s kind traditional Chinese medicinal components；
Wherein, 2≤s≤n；
The m piece patent document for treating the disease is filtered out from patent database according to disease category；
Set the sequential labeling r=k of Chinese traditional medicine composition；As r≤n, the number resolution unit operation is controlled, when r > n, control
Make the effective component judging unit operation；Wherein, k is the setting number of the sequential labeling of Chinese traditional medicine composition；
According to the traditional Chinese medicinal components in m patent documents and r kind Chinese traditional medicine composition, obtain special comprising r kind Chinese traditional medicine composition
Sharp document number Cr, patent document number S comprising the 1st kind of traditional Chinese medicinal components in r kind Chinese traditional medicine compositionr1And include r kind Chinese medicine group
The patent document number S of s kind traditional Chinese medicinal components in conjunctionrs；
Compare the patent document number S comprising the 1st kind of traditional Chinese medicinal components in r kind Chinese traditional medicine compositionr1To including r kind Chinese traditional medicine composition
In s kind traditional Chinese medicinal components patent document number Srs, obtain the single traditional Chinese medicinal components patent document number maximum value of r kind Chinese traditional medicine composition
Srmax；
According to the patent document number C comprising r kind Chinese traditional medicine compositionrWith the single traditional Chinese medicinal components patent of r kind Chinese traditional medicine composition
Document number maximum value Srmax, obtain the different degree Z of r kind Chinese traditional medicine compositionr；The different degree Z of Chinese traditional medicine compositionrIt is obtained using following formula
It arrives:
The maximum Chinese traditional medicine composition of different degree is selected from the different degree of n kind Chinese traditional medicine composition as the effective of the treatment disease
Ingredient.
Further, above-mentioned processor 200 obtains disease information for executing, and determines disease to disease information according to disease information
Sick type；The traditional Chinese medicinal components that a variety for the treatment of diseases are preset according to disease category, to the Chinese medicine group of a variety for the treatment of diseases
Divide and carry out n times combination, obtains n kind Chinese traditional medicine composition.
Further, as shown in figure 3, above-mentioned processor 200 segments m patent documents for executing, m are obtained specially
The word segmentation result of sharp document；According to the traditional Chinese medicinal components of preset a variety for the treatment of diseases, to the word segmentation result of m patent documents
Inverted index is established, participle inverted index file is obtained；Set sequential labeling f=of the traditional Chinese medicinal components in r kind Chinese traditional medicine composition
k'；Wherein, k ' is the setting number of sequential labeling of the traditional Chinese medicinal components in r kind Chinese traditional medicine composition；
As f≤s, the traditional Chinese medicinal components retrieval module operation is controlled, as f > s, the intersection module is controlled and described takes
Big processing unit operation；
The patent document comprising f kind traditional Chinese medicinal components in r kind Chinese medicine group is retrieved from participle inverted index file, is obtained
To the f kind traditional Chinese medicinal components patent document set I of r kind Chinese traditional medicine compositionrf；Wherein, 1≤f≤s；
According to the f kind traditional Chinese medicinal components patent document set I of r kind Chinese traditional medicine compositionfMiddle number of elements is obtained comprising r
The patent document number S of f kind traditional Chinese medicinal components in kind Chinese traditional medicine compositionrf；
To the 1st kind of traditional Chinese medicinal components patent document set I of r kind Chinese traditional medicine compositionr1Into the s kind of r kind Chinese traditional medicine composition
Medicine component patent document set IrsIntersection processing is carried out, the Searches of Patent Literature intersection comprising r kind Chinese traditional medicine composition is obtained；
According to number of elements in the Searches of Patent Literature intersection comprising r kind Chinese traditional medicine composition, obtain comprising r kind Chinese medicine group
The patent document number C of conjunctionr。
Wherein, memory 100 described in the embodiment of the present invention can be a storage device, be also possible to multiple storage members
The general designation of part, and for storing executable program code etc..And memory 100 may include random access memory (RAM), it can also be with
Including nonvolatile memory (non-volatile memory), such as magnetic disk storage, flash memory (Flash) etc..
Processor 200 described in the embodiment of the present invention can be a processor, be also possible to the system of multiple processing elements
Claim.For example, the processor 200 can be central processing unit (Central Processing Unit, abbreviation CPU), it is also possible to
Specific integrated circuit (Application Specific Integrated Circuit, abbreviation ASIC), or be arranged to
Implement one or more integrated circuits of the embodiment of the present invention, such as: one or more microprocessors (digital signal
Processor, abbreviation DSP), or, one or more field programmable gate array (Field Programmable Gate
Array, abbreviation FPGA).
Bus 300 described in the embodiment of the present invention can be industry standard architecture (Industry Standard
Architecture, ISA) bus, external equipment interconnection (Peripheral Component, PCI) bus or extension industry mark
Quasi- architecture (Extended Industry Standard Architecture, EISA) bus etc..The bus 300 can be with
It is divided into address bus, data/address bus, control bus etc..Only to be indicated with a thick line in Fig. 7 convenient for indicating, it is not intended that
Only a bus or a type of bus.
The above description is merely a specific embodiment, but scope of protection of the present invention is not limited thereto, any
Those familiar with the art in the technical scope disclosed by the present invention, can easily think of the change or the replacement, and should all contain
Lid is within protection scope of the present invention.Therefore, protection scope of the present invention should be based on the protection scope of the described claims.
Claims (10)
1. a kind of Chinese medicine preparation analysis of effective component method, which is characterized in that executed suitable for terminal device, the Chinese medicine is matched
Square analysis of effective component method includes:
S1: obtaining disease category, filters out the m piece patent text for treating the disease from patent database according to disease category
It offers, according to the n kind Chinese traditional medicine composition of disease described in disease category predetermined treatment；Every kind of Chinese traditional medicine composition includes s kind traditional Chinese medicinal components；
Wherein, 2≤s≤n；
S2: the sequential labeling r=1 of Chinese traditional medicine composition is set；
S3: according to the traditional Chinese medicinal components in m patent documents and r kind Chinese traditional medicine composition, the patent comprising r kind Chinese traditional medicine composition is obtained
Document number Cr, patent document number S comprising the 1st kind of traditional Chinese medicinal components in r kind Chinese traditional medicine compositionr1And include r kind Chinese traditional medicine composition
In s kind traditional Chinese medicinal components patent document number Srs；
S4: compare the patent document number S comprising the 1st kind of traditional Chinese medicinal components in r kind Chinese traditional medicine compositionr1To including r kind Chinese traditional medicine composition
In s kind traditional Chinese medicinal components patent document number Srs, obtain the single traditional Chinese medicinal components patent document number maximum value of r kind Chinese traditional medicine composition
Srmax；
S5: according to the patent document number C comprising r kind Chinese traditional medicine compositionrWith the single traditional Chinese medicinal components patent text of r kind Chinese traditional medicine composition
Offer several maximum value Srmax, obtain the different degree Z of r kind Chinese traditional medicine compositionr；
S6: setting the sequential labeling r=k of Chinese traditional medicine composition, as r≤n, executes S3；As r > n, S7 is executed, wherein k is Chinese medicine group
The setting number of the sequential labeling of conjunction；
S7: the maximum Chinese traditional medicine composition of different degree is selected from the different degree of n kind Chinese traditional medicine composition as the effective of the treatment disease
Ingredient.
2. Chinese medicine preparation analysis of effective component method according to claim 1, which is characterized in that default according to disease category
The n kind Chinese traditional medicine composition for treating the disease includes:
The traditional Chinese medicinal components that a variety of treatments diseases are preset according to disease category, to the traditional Chinese medicinal components of a variety for the treatment of diseases into
The combination of row n times, obtains n kind Chinese traditional medicine composition.
3. Chinese medicine preparation analysis of effective component method according to claim 2, which is characterized in that the various Chinese traditional medicine compositions
In traditional Chinese medicinal components quantity it is identical or different.
4. Chinese medicine preparation analysis of effective component method according to claim 2, which is characterized in that the S3 includes:
S31: m patent documents are segmented, the word segmentation result of m patent documents is obtained；
S32: according to the traditional Chinese medicinal components of preset a variety for the treatment of diseases, the row of falling is established to the word segmentation result of m patent documents
Index obtains participle inverted index file；
S33: various traditional Chinese medicinal components in r kind Chinese traditional medicine composition are retrieved from participle inverted index file, are obtained comprising r kind Chinese medicine
Combined patent document number Cr, patent document number S comprising the 1st kind of traditional Chinese medicinal components in r kind Chinese traditional medicine compositionr1And include r
The patent document number S of s kind traditional Chinese medicinal components in kind Chinese traditional medicine compositionrs。
5. Chinese medicine preparation analysis of effective component method according to claim 4, which is characterized in that the S33 includes:
S331: sequential labeling f=1 of the setting traditional Chinese medicinal components in r kind Chinese traditional medicine composition；
S332: retrieving the patent document comprising f kind traditional Chinese medicinal components in r kind Chinese medicine group from participle inverted index file,
Obtain the f kind traditional Chinese medicinal components patent document set I of r kind Chinese traditional medicine compositionrf；Wherein, 1≤f≤s；
S333: according to the f kind traditional Chinese medicinal components patent document set I of r kind Chinese traditional medicine compositionfMiddle number of elements is obtained comprising r
The patent document number S of f kind traditional Chinese medicinal components in kind Chinese traditional medicine compositionrf；
S334: sequential labeling f=k ' of the setting traditional Chinese medicinal components in r kind Chinese traditional medicine composition executes S332 as f≤s；As f > s,
Execute S335；Wherein, k ' is the setting number of sequential labeling of the traditional Chinese medicinal components in r kind Chinese traditional medicine composition；
S335: to the 1st kind of traditional Chinese medicinal components patent document set I of r kind Chinese traditional medicine compositionr1Into the s kind of r kind Chinese traditional medicine composition
Medicine component patent document set IrsIntersection processing is carried out, the Searches of Patent Literature intersection comprising r kind Chinese traditional medicine composition is obtained；
S336: it according to number of elements in the Searches of Patent Literature intersection comprising r kind Chinese traditional medicine composition, obtains comprising r kind Chinese medicine
Combined patent document number Cr。
6. described in any item Chinese medicine preparation analysis of effective component methods according to claim 1~5, which is characterized in that the r
The different degree Z of kind Chinese traditional medicine compositionrIt is obtained using following formula:
7. a kind of terminal device, which is characterized in that including the memory and processor communicated with each other；The memory is for storing
A plurality of instruction is to realize Chinese medicine preparation analysis of effective component method；The a plurality of instruction is loaded and is executed by processor:
Disease category is obtained, filters out the m piece patent document for treating the disease, root from patent database according to disease category
According to the n kind Chinese traditional medicine composition of disease described in disease category predetermined treatment；Every kind of Chinese traditional medicine composition includes s kind traditional Chinese medicinal components；Wherein,
2≤s≤n；
The m piece patent document for treating the disease is filtered out from patent database according to disease category；
Set the sequential labeling r=k of Chinese traditional medicine composition；As r≤n, control the operation of number resolution unit, as r > n, control effectively at
Divide judging unit operation；Wherein, k is the setting number of the sequential labeling of Chinese traditional medicine composition；
According to the traditional Chinese medicinal components in m patent documents and r kind Chinese traditional medicine composition, the patent text comprising r kind Chinese traditional medicine composition is obtained
Offer several Cr, patent document number S comprising the 1st kind of traditional Chinese medicinal components in r kind Chinese traditional medicine compositionr1And comprising in r kind Chinese traditional medicine composition
The patent document number S of s kind traditional Chinese medicinal componentsrs；
Compare the patent document number S comprising the 1st kind of traditional Chinese medicinal components in r kind Chinese traditional medicine compositionr1To in comprising r kind Chinese traditional medicine composition
The patent document number S of s kind traditional Chinese medicinal componentsrs, obtain the single traditional Chinese medicinal components patent document number maximum value of r kind Chinese traditional medicine composition
Srmax；
According to the patent document number C comprising r kind Chinese traditional medicine compositionrWith the single traditional Chinese medicinal components patent document number of r kind Chinese traditional medicine composition
Maximum value Srmax, obtain the different degree Z of r kind Chinese traditional medicine compositionr；
Selected from the different degree of n kind Chinese traditional medicine composition the maximum Chinese traditional medicine composition of different degree as treat the disease it is effective at
Point.
8. terminal device according to claim 7, which is characterized in that the processor obtains disease information for executing,
Disease type is determined to disease information according to disease information；The Chinese medicine group of a variety for the treatment of diseases is preset according to disease category
Point, n times combination is carried out to the traditional Chinese medicinal components of a variety for the treatment of diseases, obtains n kind Chinese traditional medicine composition.
9. terminal device according to claim 8, which is characterized in that the processor is for executing to m patent documents
It is segmented, obtains the word segmentation result of m patent documents；According to the traditional Chinese medicinal components of preset a variety for the treatment of diseases, to m
The word segmentation result of patent document establishes inverted index, obtains participle inverted index file；Traditional Chinese medicinal components are set in r kind Chinese medicine group
Sequential labeling f=k ' in conjunction；Wherein, k ' is the setting number of sequential labeling of the traditional Chinese medicinal components in r kind Chinese traditional medicine composition；
As f≤s, the operation of traditional Chinese medicinal components retrieval module is controlled, as f > s, intersection module is controlled and big processing unit is taken to run；
The patent document comprising f kind traditional Chinese medicinal components in r kind Chinese medicine group is retrieved from participle inverted index file, obtains the
The f kind traditional Chinese medicinal components patent document set I of r kind Chinese traditional medicine compositionrf；Wherein, 1≤f≤s；
According to the f kind traditional Chinese medicinal components patent document set I of r kind Chinese traditional medicine compositionfMiddle number of elements is obtained comprising r kind Chinese medicine
The patent document number S of f kind traditional Chinese medicinal components in combinationrf；
To the 1st kind of traditional Chinese medicinal components patent document set I of r kind Chinese traditional medicine compositionr1To the s kind Chinese medicine group of r kind Chinese traditional medicine composition
Divide patent document set IrsIntersection processing is carried out, the Searches of Patent Literature intersection comprising r kind Chinese traditional medicine composition is obtained；
According to number of elements in the Searches of Patent Literature intersection comprising r kind Chinese traditional medicine composition, obtain comprising r kind Chinese traditional medicine composition
Patent document number Cr。
10. according to the described in any item terminal devices of claim 7~9, which is characterized in that the weight of the r kind Chinese traditional medicine composition
Spend ZrIt is obtained using following formula:
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| CN105944072A (en) * | 2016-07-08 | 2016-09-21 | 李加义 | TraditionalChinese medicine composition for preventing and treating swine influenza |
| CN106372952A (en) * | 2016-11-14 | 2017-02-01 | 北京创业公社征信服务有限公司 | Objective and subjective weight determining multi-model compositional verification-based enterprise credit assessment method and system |
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