CN107413205A - Dialysis effluent purifying hollow-fibre membrane and its processing method - Google Patents
Dialysis effluent purifying hollow-fibre membrane and its processing method Download PDFInfo
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- CN107413205A CN107413205A CN201710808859.9A CN201710808859A CN107413205A CN 107413205 A CN107413205 A CN 107413205A CN 201710808859 A CN201710808859 A CN 201710808859A CN 107413205 A CN107413205 A CN 107413205A
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- 238000000502 dialysis Methods 0.000 title claims abstract description 31
- 239000000835 fiber Substances 0.000 title claims abstract description 24
- 239000012528 membrane Substances 0.000 title claims abstract description 24
- 238000003672 processing method Methods 0.000 title description 4
- 239000000463 material Substances 0.000 claims abstract description 107
- 239000002904 solvent Substances 0.000 claims abstract description 23
- 238000009987 spinning Methods 0.000 claims abstract description 18
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 15
- 238000001914 filtration Methods 0.000 claims abstract description 10
- 238000005406 washing Methods 0.000 claims abstract description 9
- 238000001035 drying Methods 0.000 claims abstract description 5
- 238000012545 processing Methods 0.000 claims abstract description 5
- 239000002994 raw material Substances 0.000 claims abstract description 4
- 239000011148 porous material Substances 0.000 claims description 21
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 claims description 20
- 239000000654 additive Substances 0.000 claims description 19
- 230000000996 additive effect Effects 0.000 claims description 19
- 239000007788 liquid Substances 0.000 claims description 18
- QCWXUUIWCKQGHC-UHFFFAOYSA-N Zirconium Chemical compound [Zr] QCWXUUIWCKQGHC-UHFFFAOYSA-N 0.000 claims description 11
- 229910052726 zirconium Inorganic materials 0.000 claims description 11
- -1 SPSF Polymers 0.000 claims description 10
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims description 9
- FXHOOIRPVKKKFG-UHFFFAOYSA-N N,N-Dimethylacetamide Chemical group CN(C)C(C)=O FXHOOIRPVKKKFG-UHFFFAOYSA-N 0.000 claims description 9
- SECXISVLQFMRJM-UHFFFAOYSA-N N-Methylpyrrolidone Chemical compound CN1CCCC1=O SECXISVLQFMRJM-UHFFFAOYSA-N 0.000 claims description 9
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims description 9
- 229940113088 dimethylacetamide Drugs 0.000 claims description 9
- 239000011777 magnesium Substances 0.000 claims description 9
- 229910052749 magnesium Inorganic materials 0.000 claims description 9
- 239000002245 particle Substances 0.000 claims description 9
- 229910052710 silicon Inorganic materials 0.000 claims description 9
- 239000010703 silicon Substances 0.000 claims description 9
- 238000001179 sorption measurement Methods 0.000 claims description 7
- 239000004695 Polyether sulfone Substances 0.000 claims description 6
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 6
- 229920006393 polyether sulfone Polymers 0.000 claims description 6
- 229920001223 polyethylene glycol Polymers 0.000 claims description 6
- 238000002360 preparation method Methods 0.000 claims description 6
- 239000002202 Polyethylene glycol Substances 0.000 claims description 3
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 3
- MSKSOBAQMWJYTJ-UHFFFAOYSA-N [Mg].OP(O)(O)=O Chemical compound [Mg].OP(O)(O)=O MSKSOBAQMWJYTJ-UHFFFAOYSA-N 0.000 claims description 3
- GDKWXCWTFCPDFQ-UHFFFAOYSA-N [Si].OP(O)(O)=O Chemical compound [Si].OP(O)(O)=O GDKWXCWTFCPDFQ-UHFFFAOYSA-N 0.000 claims description 3
- 239000008187 granular material Substances 0.000 claims description 3
- ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 claims description 3
- 239000001095 magnesium carbonate Substances 0.000 claims description 3
- 229910000021 magnesium carbonate Inorganic materials 0.000 claims description 3
- 239000012299 nitrogen atmosphere Substances 0.000 claims description 3
- RVTZCBVAJQQJTK-UHFFFAOYSA-N oxygen(2-);zirconium(4+) Chemical compound [O-2].[O-2].[Zr+4] RVTZCBVAJQQJTK-UHFFFAOYSA-N 0.000 claims description 3
- 229920003229 poly(methyl methacrylate) Polymers 0.000 claims description 3
- 229920002492 poly(sulfone) Polymers 0.000 claims description 3
- 239000004926 polymethyl methacrylate Substances 0.000 claims description 3
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 3
- 239000000377 silicon dioxide Substances 0.000 claims description 3
- FDNAPBUWERUEDA-UHFFFAOYSA-N silicon tetrachloride Chemical compound Cl[Si](Cl)(Cl)Cl FDNAPBUWERUEDA-UHFFFAOYSA-N 0.000 claims description 3
- 238000010792 warming Methods 0.000 claims description 3
- 229910001928 zirconium oxide Inorganic materials 0.000 claims description 3
- DUNKXUFBGCUVQW-UHFFFAOYSA-J zirconium tetrachloride Chemical compound Cl[Zr](Cl)(Cl)Cl DUNKXUFBGCUVQW-UHFFFAOYSA-J 0.000 claims description 3
- CPLXHLVBOLITMK-UHFFFAOYSA-N Magnesium oxide Chemical compound [Mg]=O CPLXHLVBOLITMK-UHFFFAOYSA-N 0.000 claims 2
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 claims 1
- 239000000395 magnesium oxide Substances 0.000 claims 1
- 229910052698 phosphorus Inorganic materials 0.000 claims 1
- 239000011574 phosphorus Substances 0.000 claims 1
- 229920000747 poly(lactic acid) Polymers 0.000 claims 1
- 239000004626 polylactic acid Substances 0.000 claims 1
- 230000008901 benefit Effects 0.000 abstract description 4
- 239000010808 liquid waste Substances 0.000 abstract description 2
- 239000004088 foaming agent Substances 0.000 abstract 2
- 238000010521 absorption reaction Methods 0.000 description 10
- 239000000243 solution Substances 0.000 description 9
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 8
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 8
- 239000004202 carbamide Substances 0.000 description 8
- 239000003053 toxin Substances 0.000 description 7
- 231100000765 toxin Toxicity 0.000 description 7
- 239000002699 waste material Substances 0.000 description 7
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 description 6
- 229910019142 PO4 Inorganic materials 0.000 description 6
- 239000003463 adsorbent Substances 0.000 description 6
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 description 6
- 239000002158 endotoxin Substances 0.000 description 6
- 150000002500 ions Chemical class 0.000 description 6
- 239000010452 phosphate Substances 0.000 description 6
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 5
- 241000894006 Bacteria Species 0.000 description 5
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 5
- ZHNUHDYFZUAESO-UHFFFAOYSA-N Formamide Chemical compound NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 description 4
- 241000209094 Oryza Species 0.000 description 4
- 235000007164 Oryza sativa Nutrition 0.000 description 4
- 235000012489 doughnuts Nutrition 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 4
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 4
- 230000014759 maintenance of location Effects 0.000 description 4
- 235000009566 rice Nutrition 0.000 description 4
- 150000003384 small molecules Chemical class 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 208000001647 Renal Insufficiency Diseases 0.000 description 3
- 241000700605 Viruses Species 0.000 description 3
- 229940109239 creatinine Drugs 0.000 description 3
- 238000002389 environmental scanning electron microscopy Methods 0.000 description 3
- 210000003734 kidney Anatomy 0.000 description 3
- 201000006370 kidney failure Diseases 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 239000000758 substrate Substances 0.000 description 3
- ATRRKUHOCOJYRX-UHFFFAOYSA-N Ammonium bicarbonate Chemical compound [NH4+].OC([O-])=O ATRRKUHOCOJYRX-UHFFFAOYSA-N 0.000 description 2
- 229920001661 Chitosan Polymers 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 2
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 description 2
- 239000001099 ammonium carbonate Substances 0.000 description 2
- 235000012501 ammonium carbonate Nutrition 0.000 description 2
- 235000013339 cereals Nutrition 0.000 description 2
- 208000020832 chronic kidney disease Diseases 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- GUJOJGAPFQRJSV-UHFFFAOYSA-N dialuminum;dioxosilane;oxygen(2-);hydrate Chemical compound O.[O-2].[O-2].[O-2].[Al+3].[Al+3].O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O GUJOJGAPFQRJSV-UHFFFAOYSA-N 0.000 description 2
- 239000000385 dialysis solution Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 238000001631 haemodialysis Methods 0.000 description 2
- 239000012510 hollow fiber Substances 0.000 description 2
- 239000004310 lactic acid Substances 0.000 description 2
- 235000014655 lactic acid Nutrition 0.000 description 2
- 238000005374 membrane filtration Methods 0.000 description 2
- 229910052901 montmorillonite Inorganic materials 0.000 description 2
- 230000003647 oxidation Effects 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- 238000005191 phase separation Methods 0.000 description 2
- 229920006316 polyvinylpyrrolidine Polymers 0.000 description 2
- 238000000746 purification Methods 0.000 description 2
- 238000009738 saturating Methods 0.000 description 2
- 229940116269 uric acid Drugs 0.000 description 2
- 229910000166 zirconium phosphate Inorganic materials 0.000 description 2
- LEHFSLREWWMLPU-UHFFFAOYSA-B zirconium(4+);tetraphosphate Chemical compound [Zr+4].[Zr+4].[Zr+4].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O LEHFSLREWWMLPU-UHFFFAOYSA-B 0.000 description 2
- 208000037157 Azotemia Diseases 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- 239000004411 aluminium Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 238000000280 densification Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 208000028208 end stage renal disease Diseases 0.000 description 1
- 201000000523 end stage renal failure Diseases 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000000322 hemodialysis Effects 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000005180 public health Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 208000009852 uremia Diseases 0.000 description 1
- 238000004804 winding Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
- B01D71/06—Organic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1654—Dialysates therefor
- A61M1/1656—Apparatus for preparing dialysates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
- B01D67/0002—Organic membrane manufacture
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
- B01D69/08—Hollow fibre membranes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2311/00—Details relating to membrane separation process operations and control
- B01D2311/26—Further operations combined with membrane separation processes
- B01D2311/2626—Absorption or adsorption
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2323/00—Details relating to membrane preparation
- B01D2323/15—Use of additives
- B01D2323/18—Pore-control agents or pore formers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2325/00—Details relating to properties of membranes
- B01D2325/02—Details relating to pores or porosity of the membranes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Manufacturing & Machinery (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- External Artificial Organs (AREA)
Abstract
One kind dialysis effluent purifying hollow-fibre membrane, is related to dialysis liquid waste treating apparatus field, is formed by following Raw material processings：Film base material material, pore-foaming agent, solvent, specific nano sorbing material；Hollow-fibre membrane internal diameter is 220 350 microns, wall thickness is 40 60 microns, film wire ecto-entad is divided into exodermis, intermediate layer and endodermis three parts, specific nano sorbing material is distributed in the exodermis and intermediate layer of film, 5 10 microns of skin thickness, and its average filtration aperture is 46 nanometers；0.5 5 microns of endodermis thickness, its average filtration aperture are 0.5 1 nanometers.Film base material material, pore-foaming agent, solvent and specific porous adsorbing material to be chosen, spinning solution is made at room temperature, is bathed after spinning head is extruded by 30 60cm vapor, temperature maintains 60 80 degree, most afterwards through washing, drying, finished product.The present invention has the advantages that inflow-rate of water turbine is big, service life length, and single treatment ability is strong.
Description
Technical field
The present invention relates to dialysis liquid waste treating apparatus field, say it is that a kind of adsorbent will not enter the circulatory system in detail, can
The dialysis waste liquid of the effectively various toxin ions such as isolation urase, absorption ammonium ion, free phosphate radical and sulfate ion is net
Change hollow-fibre membrane and its processing method.
Background technology
It is known that kidney trouble is a global public health problem, the whole world, which there are about 2,400,000 patients with renal failure, to be needed
Dialyse.Due to aging population and the increase of diabetes illness probability, the quantity of patients with renal failure is also constantly rising（Often
Year increase 7-8%）.CKD can influence we 1/10th people.For unfortunately suffering from the people of renal failure, it is good for
Health is gradually swallowed.At home, end stage renal failure patient, common people cry " uremia ", many patients by haemodialysis or
Kidney transplant substitutes renal function.
Kidney patient often has many troubles in treatment, for example to arrive hospital regularly and be dialysed, with clear
Except the toxin of accumulation, but two kinds of currently a popular dialysis：Hemodialysis and peritoneal dialysis therapy, it is time-consuming longer,
And dialysis needs substantial amounts of dialyzate every time, this virtually adds the expenditure of medical expense, also limit two kinds of dialysis sides
The development that formula is dialysed to packaged type, because dialysis needs to carry a few decaliter dialyzates every time.
To solve problem above, dialyzate purify and circulating repetition uses, is the main flow of technology today research.Enter
Gone dialysis dialysis waste liquid in mainly contain urea, creatinine, phosphate, B2M, be recycled for a long time during band
The endotoxin material such as virus and bacteria entered, how to remove these materials is that the key technology that dialysis effluent purifying is reused is asked
Topic.With the development of dialyzate circulating technology, various new dialyzate recovery systems are developed, such as Temasek science and engineering
The patent of institute（) and Zhuhai Jian Fan scientific ＆ technical corporation CN106111079A（CN205515729U patent) all propose using urase or
Adsorbent carries out circular regeneration to dialysis waste liquid.Adsorbent mainly includes zirconium base, aluminium base and activated carbon, and enzyme used is mainly urea
Enzyme.These materials are successively emitted in adsorbent equipment, and long-term use has the less adsorbent of particle diameter or urase entrance follows
Loop system, causes the pollution of whole dialysis fluid circulation, and the dialysis to patient brings greater risk.
The content of the invention
Present invention aim to address above-mentioned the deficiencies in the prior art, there is provided and a kind of adsorbent will not enter the circulatory system,
Urase can effectively be completely cut off, the various toxin such as ammonium ion, free phosphate radical and sulfate ion after absorption urea decomposes from
The dialysis effluent purifying hollow-fibre membrane and its processing method of son.
Technical scheme is used by the present invention solves above-mentioned the deficiencies in the prior art：
One kind dialysis effluent purifying hollow-fibre membrane, it is characterised in that formed by the Raw material processing of following proportion by weight：Bag
The specific nano for including the film base material material of 15-20 parts, the pore type additive of 3-10 parts, the solvent of 75-80 parts, and 2-4 parts is inhaled
Enclosure material；Hollow-fibre membrane internal diameter is 220-350 microns, wall thickness is 40-60 microns, film wire ecto-entad be divided into exodermis, in
Interbed and endodermis three parts, specific nano sorbing material is distributed in the exodermis and intermediate layer of film, its particle diameter 1-8nm,
Exodermis to the specific nano sorbing material density in intermediate layer is gradually reduced, in endodermis without specific nano sorbing material；
The skin thickness 5-10 microns of film wire, its average filtration aperture are 4-6 nanometers；The endodermis thickness 0.5-5 microns of film wire, its
Average filtration aperture is 0.5-1 nanometers.
Heretofore described film base material material is polysulfones, SPSF, polyether sulfone, sulfonated polyether sulfone, Kynoar, poly-
One or more in lactic acid, polymethyl methacrylate, polyvinyl alcohol；Described pore type additive is polyvinylpyrrolidine
Alkanone（PVP）Or polyethylene glycol（At least one of PEG)；Solvent is dimethyl acetamide (DMAC), dimethylformamide
（DMF）, one or more in 1-METHYLPYRROLIDONE (NMP).
Heretofore described specific nano sorbing material is silicon-based adsorption material material, zirconium base sorbing material and magnesium-based absorption
At least one of material.
Silicon-based adsorption material material described in invention is at least one of silica, silicon chloride, phosphoric acid silicon grain；Described
Zirconium base sorbing material is at least one of zirconium oxide, zirconium chloride, zirconium phosphate particles.Described magnesium-based sorbing material is oxidation
At least one of magnesium, magnesium carbonate, phosphoric acid magnesium granules.
A kind of preparation method for effluent purifying hollow-fibre membrane of dialysing, it is characterised in that comprise the following steps：
A, by proportion by weight choose 15-20 parts film base material material, the pore type additive of 3-10 parts, the solvent of 75-80 parts, and
The specific porous adsorbing material of 2-4 parts；
B, at room temperature, pore type additive is added in solvent, after pore type additive all dissolving, adds film base material material
With specific porous adsorbing material, 70-100 degree is warming up to, 18-26h is sufficiently stirred in nitrogen atmosphere, makes consolidating in spinning solution
The full and uniform dissolving of body material, vacuumizing and defoaming, is made spinning solution；
C, spinning solution is extruded with core liquid through spinning head, 30-60cm vapor is then passed through with the speed of 10-15 rice per minute
Bath, the temperature of vapor bath maintain 60-80 degree, are most washed afterwards through water wash system, drying system drying, finished product.
Heretofore described core liquid is the mixed liquor of concentration 10-20% solvents and water.Described core liquid solvent can be diformazan
At least one of base formamide, dimethyl acetamide, 1-METHYLPYRROLIDONE.
Heretofore described water wash system washing is made up of 60 degree, 70 degree, 80 degree and the water washing devices of 90 Du tetra-.
All solvents in this water-washing process spinning solution, most perforating agents（Such as PVP) and specific nano
Sorbing material（Such as silicon substrate or zirconium base or magnesium-base nano sorbing material）It can be moved to film exodermis, and be finally completed phase separation.
For the present invention in use, coordinating urase and porous adsorbing material to use, urase resolves into the urea in waste liquid of dialysing
Ammonium carbonate, uric acid, the organic substance such as creatinine in porous adsorbing material absorption dialysis waste liquid, the then dialysis by the present invention are given up
The endotoxin such as liquid purification doughnut membrane filtration, present invention filtering retention bacterium, virus and the small molecule eluted are porous
Sorbing material（Activated carbon, chitosan, montmorillonite）And urase, specific nano sorbing material then adsorbable various toxin ions.
The present invention is fixed on exodermis and the intermediate layer of doughnut membranous wall by the way that specific nano sorbing material is processed, and plays fixation
While do not influence its function, the addition of the hierarchical specific nano sorbing material of hollow-fibre membrane, make the present invention to saturating
The effluent purifying used time is analysed, it is various to play ammonium ion, free phosphate radical and sulfate ion after absorption urea decomposes etc.
The effect of toxin ion, while the small molecule porous adsorbing material and urase eluted in previous step can be filtered out；With excessively stream
The advantages that amount is big, service life length, and single treatment ability is strong.
Brief description of the drawings
Fig. 1 be exodermis of the present invention outer surface SEM ESEMs under structure chart.
Fig. 2 is this hair intermediate layer（Film wire wall）Mid-section structure chart under SEM ESEMs.
Fig. 3 be endodermis of the present invention inner surface SEM ESEMs under structure chart.
Embodiment
One kind dialysis effluent purifying hollow-fibre membrane, it is characterised in that by the Raw material processing of following proportion by weight
Into：Film base material material including 15-20 parts, the pore type additive of 3-10 parts, the solvent of 75-80 parts, and the specificity of 2-4 parts are received
Rice sorbing material；Hollow-fibre membrane（Film wire）Internal diameter is 220-350 microns, wall thickness is 40-60 microns, and film wire ecto-entad is divided into
Exodermis, intermediate layer and endodermis three parts, the pore size filter of film wire endodermis are less than the pore size filter of outer layer, specific nano
Sorbing material is distributed in film（Silk）Exodermis and intermediate layer in, its particle diameter 1-8nm, exodermis to intermediate layer specific nano inhale
Enclosure material density is gradually reduced, preferred without specific nano sorbing material, the particle diameter of specific nano sorbing material in endodermis
2-4nm；The skin thickness 5-10 microns of film wire, its average filtration aperture are 4-6 nanometers；The endodermis thickness 0.5-5 of film wire
Micron, its average filtration aperture is 0.5-1 nanometers.
Heretofore described film base material material is polysulfones, SPSF, polyether sulfone, sulfonated polyether sulfone, Kynoar, poly-
One or more in lactic acid, polymethyl methacrylate, polyvinyl alcohol；Described pore type additive is polyvinylpyrrolidine
Alkanone（PVP）Or polyethylene glycol（At least one of PEG)；Solvent is dimethyl acetamide (DMAC), dimethylformamide
（DMF）, one or more in 1-METHYLPYRROLIDONE (NMP).
Heretofore described specific nano sorbing material is silicon-based adsorption material material, zirconium base sorbing material and magnesium-based absorption
At least one of material.
Silicon-based adsorption material material described in invention is at least one of silica, silicon chloride, phosphoric acid silicon grain；Described
Zirconium base sorbing material is at least one of zirconium oxide, zirconium chloride, zirconium phosphate particles.Described magnesium-based sorbing material is oxidation
At least one of magnesium, magnesium carbonate, phosphoric acid magnesium granules.
A kind of preparation method for effluent purifying hollow-fibre membrane of dialysing, it is characterised in that comprise the following steps：
A, by proportion by weight choose 15-20 parts film base material material, the pore type additive of 3-10 parts, the solvent of 75-80 parts, and
The specific porous adsorbing material of 2-4 parts；
B, at room temperature, pore type additive is added in solvent, after pore type additive all dissolving, adds film base material material
With specific porous adsorbing material, 70-100 degree is warming up to, 18-26h is sufficiently stirred in nitrogen atmosphere, makes consolidating in spinning solution
The full and uniform dissolving of body material, vacuumizing and defoaming, is made spinning solution；
C, spinning solution is put into hollow fiber spinning machine with core liquid, extruded through spinning head, then with the speed of 10-15 rice per minute
Vapor bath of the degree by 30-60cm length, the temperature of vapor bath maintain 60-80 degree, most wash, dry through water wash system afterwards
System is dried, and is collected by winding apparatus, finished product.
The vapor bath of 60-80 degree can make exodermis form macroporous structure, and this steam bath will can gather at the endodermis of film
Vinyl pyrrolidone (pore type additive）It is attracted to the exodermis of film, and PVP（Pore type additive)
In moving process from inside to outside, the specific nano sorbing material at endodermis can be driven to be moved to exodermis, most end form
Be gradually reduced into exodermis to intermediate layer specific nano sorbing material density, in endodermis without specific nano sorbing material
Hollow fiber film structure, it can be good at playing the absorption of each layer or retain advantage, the specificity in exodermis and intermediate layer is received
Rice sorbing material adsorbs to some ions from dialyzate first, and endodermis then can not to specific nano sorbing material
The material of absorption continues more efficient retention, is greatly improved absorption and retention efficiency.Sequentially entered by the film of steam bath
In 60 degree, 70 degree, 80 degree and the water wash systems of 90 Du tetra-, all solvents in this water-washing process spinning solution, the overwhelming majority
Pore type additive（Such as PVP) and specific nano sorbing material moved to film exodermis, it is and final complete
Into phase separation（Solvent in spinning solution, pass additive are eluted）.
Because high-temperature water vapor is bathed, specific nano sorbing material can be embedded in intermediate layer and the outermost layer of film,
As shown in Fig. 1-Fig. 3 SEM structure photos, the endodermis of film forms the thick fine and close selective separating of 1-2 microns, film on its endodermis
The average pore size in hole is that the heat source substance such as 0.5-1nm, all bacteriums, endotoxin can not all pass through the filter layer.
Heretofore described core liquid is the mixed liquor of concentration 10-20% solvents and water.Described core liquid solvent can be diformazan
At least one of base formamide, dimethyl acetamide, 1-METHYLPYRROLIDONE.
Heretofore described water wash system washing is made up of 60 degree, 70 degree, 80 degree and the water washing devices of 90 Du tetra-.
For the present invention in use, coordinating urase and porous adsorbing material to use, urase resolves into the urea in waste liquid of dialysing
Ammonium carbonate, uric acid, the organic substance such as creatinine in porous adsorbing material absorption dialysis waste liquid, the then dialysis by the present invention are given up
The endotoxin such as liquid purification doughnut membrane filtration, present invention filtering retention bacterium, virus and the small molecule eluted are porous
Sorbing material（Activated carbon, chitosan, montmorillonite）And urase, specific nano sorbing material then adsorbable various toxin ions.
The present invention is fixed on exodermis and the intermediate layer of doughnut membranous wall by the way that specific nano sorbing material is processed, and plays fixation
While do not influence its function, the addition of the hierarchical specific nano sorbing material of hollow-fibre membrane, make the present invention to saturating
When analysing effluent purifying, play and adsorbing（After urea decomposes）Ammonium ion, free phosphate radical and sulfate ion etc. are various
The effect of toxin ion, while the small molecule porous adsorbing material and urase eluted in previous step can be filtered out；With excessively stream
The advantages that amount is big, service life length, and single treatment ability is strong.
The dialysis effluent purifying hollow-fibre membrane and its manufacture method of the offer of the present invention, its exodermis, intermediate layer
Specific nano sorbing material（Silicon substrate, zirconium base or magnesium-based sorbing material）Ammonium ion after adsorbable urea decomposition, Yi Jiyou
From phosphate radical and sulfate ion, the compact texture of endodermis can all retain almost all of endotoxin.This layering
Structure design not only can effectively fix nano adsorption material and also densification endodermis in effectively catching bacterium, endotoxin
Deng heat source substance simultaneously, moreover it is possible to inhale the activated carbon eluted in upper early stage processing procedure, urase or even the silicon substrate to come off or zirconium base
Attached particle retains again, plays a part of multiple-protection.
Claims (8)
1. one kind dialysis effluent purifying hollow-fibre membrane, it is characterised in that formed by the Raw material processing of following proportion by weight：
Film base material material including 15-20 parts, the pore type additive of 3-10 parts, the solvent of 75-80 parts, the specific nano of 2-4 parts are inhaled
Enclosure material；Hollow-fibre membrane internal diameter is 220-350 microns, wall thickness is 40-60 microns, film wire ecto-entad be divided into exodermis, in
Interbed and endodermis three parts, specific nano sorbing material is distributed in the exodermis and intermediate layer of film, its particle diameter 1-8nm；
The skin thickness 5-10 microns of film wire, its average filtration aperture are 4-6 nanometers；The endodermis thickness 0.5-5 microns of film wire, its
Average filtration aperture is 0.5-1 nanometers.
2. dialysis effluent purifying hollow-fibre membrane according to claim 1, it is characterised in that described film base material material is
In polysulfones, SPSF, polyether sulfone, sulfonated polyether sulfone, Kynoar, PLA, polymethyl methacrylate, polyvinyl alcohol
One or more；Described pore type additive is PVP（PVP）Or polyethylene glycol（PEG in) at least
It is a kind of；Solvent is dimethyl acetamide (DMAC), dimethylformamide（DMF）, one kind in 1-METHYLPYRROLIDONE (NMP) or
It is a variety of.
3. dialysis effluent purifying hollow-fibre membrane according to claim 1, it is characterised in that described specific nano
Sorbing material is at least one of silicon-based adsorption material material, zirconium base sorbing material and magnesium-based sorbing material.
4. dialysis effluent purifying hollow-fibre membrane according to claim 1, it is characterised in that described silicon-based adsorption material
Expect at least one of silica, silicon chloride, phosphoric acid silicon grain；Described zirconium base sorbing material is zirconium oxide, zirconium chloride, phosphorus
At least one of sour zirconium particle；Described magnesium-based sorbing material is at least one in magnesia, magnesium carbonate, phosphoric acid magnesium granules
Kind.
5. a kind of preparation method for effluent purifying hollow-fibre membrane of dialysing, it is characterised in that comprise the following steps：
A, by proportion by weight choose 15-20 parts film base material material, the pore type additive of 3-10 parts, the solvent of 75-80 parts, and
The specific porous adsorbing material of 2-4 parts；
B, at room temperature, pore type additive is added in solvent, after pore type additive all dissolving, adds film base material material
With specific porous adsorbing material, 70-100 degree is warming up to, 18-26h is sufficiently stirred in nitrogen atmosphere, makes consolidating in spinning solution
The full and uniform dissolving of body material, vacuumizing and defoaming, is made spinning solution；
C, spinning solution is extruded with core liquid through spinning head, then bathed by 30-60cm vapor, the temperature of vapor bath maintains
In 60-80 degree, most washed afterwards through water wash system, drying system drying, finished product.
6. the preparation method of dialysis effluent purifying hollow-fibre membrane according to claim 5, it is characterised in that the present invention
Described in water wash system washing by 60 degree, 70 degree, 80 degree and the water washing devices of 90 Du tetra- composition.
7. the preparation method of the dialysis effluent purifying hollow-fibre membrane according to claim 5 or 6, it is characterised in that described
Core liquid for concentration 10-20% solvents and water mixed liquor.
8. the preparation method of dialysis effluent purifying hollow-fibre membrane according to claim 7, it is characterised in that described
Core liquid solvent can be at least one of dimethylformamide, dimethyl acetamide, 1-METHYLPYRROLIDONE.
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| CN107413205B (en) | 2020-07-14 |
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Address after: No.20, Xingshan Road, Weihai Torch hi tech Industrial Development Zone, Weihai City, Shandong Province, 264210 Patentee after: Shandong Weigao blood purification products Co.,Ltd. Address before: No.20, Xingshan Road, torch hi tech Industrial Development Zone, Weihai City, Shandong Province 264200 Patentee before: WEIHAI WEIGAO BLOOD PURIFICATION PRODUCTS Co.,Ltd. |