CN107412650B - Foot massage physiotherapy composition, foot massage physiotherapy cream and preparation method thereof - Google Patents

Foot massage physiotherapy composition, foot massage physiotherapy cream and preparation method thereof Download PDF

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CN107412650B
CN107412650B CN201710700660.4A CN201710700660A CN107412650B CN 107412650 B CN107412650 B CN 107412650B CN 201710700660 A CN201710700660 A CN 201710700660A CN 107412650 B CN107412650 B CN 107412650B
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parts
water
filtrate
cream
foot massage
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CN107412650A (en
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窦靖鑫
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Jilin Hongliman Biotechnology Co.,Ltd.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9062—Alpinia, e.g. red ginger or galangal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A61K36/12—Filicopsida or Pteridopsida
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/324—Boswellia, e.g. frankincense
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/898—Orchidaceae (Orchid family)
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    • A61K36/898—Orchidaceae (Orchid family)
    • A61K36/8988—Gastrodia
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
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    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
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    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
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    • A61K8/73—Polysaccharides
    • A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
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    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
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    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract

The foot massage physiotherapy cream provided by the invention extracts biological effective components from ginseng root, angelica, seabuckthorn fruit, gastrodia elata, salvia miltiorrhiza, red paeony root, frankincense, galangal, cinnamon, bletilla striata and rhizoma cibotii as main components, and the herbal compound extracts have the effects of moistening skin, relaxing muscles and tendons, relieving pain, promoting blood circulation to remove blood stasis, and accelerating local and body blood circulation; the combination of superoxide dismutase with biological activity, amino acids such as sodium hyaluronate, collagen, serine and allantoin increases the effects of preventing skin aging, softening and keeping stratum corneum moisture and preventing and treating chap. The invention provides a foot massage physiotherapy cream which comprises the following components: the massage cream has the effects of softening skin and increasing skin penetration during massage, and is convenient for effective nutrient substances to penetrate into the deep part of the skin; the effective components are applied to skin in combination with massage, so as to achieve the effects of caring skin, softening and moisturizing, preventing chapping, promoting blood circulation for removing blood stasis, relieving rigidity of muscles and pain, relieving fatigue and accelerating blood circulation through massage.

Description

Foot massage physiotherapy composition, foot massage physiotherapy cream and preparation method thereof
Technical Field
The invention belongs to the field of traditional Chinese medicine and physiotherapy health care, and particularly relates to a foot massage physiotherapy composition, foot massage physiotherapy cream and a preparation method thereof.
Background
In recent years, along with the development of science and technology, the society advances, the living standard of people is improved, and a new demand for health is provided, so that the practice of headache treatment and foot pain treatment cannot keep up with the development of times. Ancient physicians Hua Tuo is named in Zuxin dao: soaking feet in the spring to raise yang and relieve exhaustion; the dampness can be removed when the feet are soaked in the summer; soaking feet in autumn to moisten intestines; in winter, the feet are soaked in the red field and are scorched. We see the ancient understanding and emphasis on the "foot". The progress of society prompts people not always to stay in the original traditional Chinese medicine foot-soaking stage. The potential of people to have a new question about products with higher functions, convenient use, strong permeability and multiple complex functions! The theory of traditional Chinese medicine channels and collaterals considers that: the five zang organs and six fu organs of the human body have corresponding acupuncture points on the feet, which are the convergence points of all meridians, and the feet are regarded as the second heart of the human body in the west. The European and American theory of foot reflex considers that the different manifestations of each part of the human foot can reflect the pathological changes of different organs of the human body. Since both feet are located far from the heart, blood circulation disorder easily occurs, and harmful substances brought from various parts of the body are likely to be deposited therein due to the influence of the gravity of the earth. Experts abroad think that symptoms can appear on the feet when the pathological change degree reaches 10 percent, and the pathological change degree reaches 70 percent when the human body generates intuition symptoms and can be detected by medical instruments.
Tests prove that after the metabolic residues left on the feet are massaged, the metabolic residues are discharged out of the body through the urinary system and other excretory organs along with accelerated blood circulation, so that the discharged urine is very turbid and has strong smell after the feet are massaged for 3-5 days. The foot massage can improve blood circulation, reduce heart burden, reduce pathological change probability of other organs, and improve metabolism ability.
Disclosure of Invention
In order to solve the problems, the invention provides a foot massage composition, a foot massage physical therapy cream and a preparation method thereof, wherein the foot massage composition and the foot massage physical therapy cream are prepared by organically combining active ingredients of traditional Chinese medicine herbs with modern medical materials and matrix materials, and are used for improving sub-health and metabolism quality.
The invention aims to provide a foot massage physiotherapy composition.
Another object of the present invention is to provide a foot massage physiotherapy cream.
The invention also aims to provide a preparation method of the foot massage physiotherapy cream.
The foot massage physiotherapy composition according to the specific embodiment of the invention comprises 1000 parts by weight of the following raw materials, wherein: 10-70 parts of ginseng root, 5-20 parts of angelica, 5-20 parts of sea buckthorn fruit, 30-100 parts of superoxide dismutase, 10-40 parts of gastrodia elata, 10-40 parts of salvia miltiorrhiza, 5-20 parts of red paeony root, 3-15 parts of frankincense, 2-10 parts of galangal, 2-10 parts of cinnamon, 10-70 parts of bletilla striata, 7-20 parts of rhizoma cibotii, 2-20 parts of sodium hyaluronate, 3-20 parts of allantoin, 3-20 parts of serine, 5-50 parts of collagen, 5-15 parts of trehalose, 1-5 parts of borneol and the balance of water.
The foot massage physiotherapy composition according to the embodiment of the invention preferably comprises the following raw materials in parts by weight: the composition comprises the following raw materials in parts by weight: 35 parts of ginseng root, 7.5 parts of angelica, 7.5 parts of sea-buckthorn fruit, 100 parts of superoxide dismutase, 10 parts of gastrodia elata, 7.5 parts of salvia miltiorrhiza, 7.5 parts of red paeony root, 5 parts of frankincense, 3 parts of galangal, 3 parts of cinnamon, 35 parts of bletilla striata, 10 parts of rhizoma cibotii, 5 parts of sodium hyaluronate, 15 parts of allantoin, 10 parts of serine, 15 parts of collagen, 10 parts of trehalose, 5 parts of borneol and 709 parts of water.
The foot massage physiotherapy ointment comprises the following raw materials in parts by weight of 1000, wherein: 10-70 parts of ginseng root, 5-20 parts of angelica, 5-20 parts of sea buckthorn fruit, 30-100 parts of superoxide dismutase, 10-40 parts of gastrodia elata, 10-40 parts of salvia miltiorrhiza, 5-20 parts of red paeony root, 3-15 parts of frankincense, 2-10 parts of galangal, 2-10 parts of cinnamon, 10-70 parts of bletilla striata, 7-20 parts of rhizoma cibotii, 2-20 parts of sodium hyaluronate, 3-20 parts of allantoin, 3-20 parts of serine, 5-50 parts of collagen, 5-15 parts of trehalose, 1-5 parts of borneol, 2-6 parts of carbomer, 10-50 parts of triethanolamine, 50-200 parts of glycerol, 10-50 parts of jojoba seed oil, 5-30 parts of spermaceti, 3-15 parts of glyceryl monostearate and the balance of water.
According to the foot massage physiotherapy cream of the specific embodiment of the present invention, preferably, the rheology modifier is carbomer, and the emulsifier is triethanolamine, glycerol, jojoba seed oil, spermaceti, and glyceryl monostearate.
The preparation method of the foot massage physiotherapy cream according to the specific embodiment of the invention comprises the following steps:
(1) preparing a herbal mixed extract: weighing ginseng root, Chinese angelica, seabuckthorn fruit, tall gastrodia tuber, red sage root, red paeony root, frankincense, galangal rhizome, cassia bark, bletilla and east Asian tree fern rhizome, adding 8-10 times of water by weight, heating to boil, cooling to 75-85 ℃, preserving heat and extracting for 2.5-3.5h, filtering to obtain a first filtrate, adding 6-8 times of water by weight into filter residue, heating to boil, cooling to 75-85 ℃, preserving heat and extracting for 1.5-2.5h, filtering to obtain a second filtrate, adding 4-6 times of water by weight into the filter residue, heating to boil, cooling to 75-85 ℃, preserving heat and extracting for 0.5-1.5h, filtering to obtain a third filtrate, combining the first filtrate, the second filtrate and the third filtrate to obtain a mixed filtrate, standing for precipitation, filtering and concentrating to obtain a mixed extract of the herbal medicine;
(2) preparing a base liquid: weighing carbomer, adding 30-40 times of water, soaking, sequentially adding trehalose and glycerol, stirring, and sterilizing to obtain base solution;
(3) preparing a mixed solution: weighing superoxide dismutase and sodium hyaluronate, adding 1-4 times of water, mixing, filtering, and sterilizing to obtain mixed solution;
(4) adding the mixed herbal extract obtained in the step (1), the mixed solution obtained in the step (3), allantoin, serine, collagen, jojoba seed oil, spermaceti, glyceryl monostearate and borneol into the base solution obtained in the step (2), adding water until the total weight of the raw materials and the water is 1000 parts, stirring and mixing uniformly, and sealing and emulsifying for 24-48h to obtain the foot massage physical therapy cream.
According to the method for preparing the foot massage physiotherapy cream according to the embodiment of the invention, preferably, in the step (1), the supernatant of the mixed filtrate to be settled is taken and sieved by a 100-200-mesh sieve.
According to the method for preparing the foot massage physiotherapy cream according to the embodiment of the present invention, preferably, in the step (1), the raw material is concentrated to a weight ratio of the raw material to water of 1: 1-1.5.
According to the method for preparing the foot massage physiotherapy cream according to the embodiment of the present invention, preferably, in the step (1), the temperature of the standing precipitation is 6 to 10 ℃.
According to the method for preparing the foot massage physiotherapy cream according to the embodiment of the present invention, preferably, in the step (2), the soaking time is 2 to 5 days.
According to the preparation method of the foot massage physiotherapy cream provided by the embodiment of the invention, preferably, in the step (2), the sterilization temperature is 112-122 ℃, and the sterilization time is 20-30 min.
According to the method for preparing the foot massage physiotherapy cream according to the embodiment of the present invention, preferably, in the step (3), the superoxide dismutase and the sodium hyaluronate which are uniformly mixed are sterilized by using a microporous filter membrane, and the pore diameter of the microporous filter membrane is not more than 0.2 μm.
According to the method for preparing the foot massage physiotherapy cream according to the embodiment of the present invention, preferably, in the step (4), the stirring temperature is 30 to 45 ℃.
The invention has the beneficial effects that:
the foot massage physiotherapy cream provided by the invention extracts biological effective components from ginseng root, angelica, seabuckthorn fruit, gastrodia elata, salvia miltiorrhiza, red paeony root, frankincense, galangal, cinnamon, bletilla striata and rhizoma cibotii as main components, and the herbal compound extracts have the effects of moistening skin, relaxing muscles and tendons, relieving pain, promoting blood circulation to remove blood stasis, and accelerating local and body blood circulation; the combination of superoxide dismutase with biological activity, amino acids sodium hyaluronate, collagen, serine and allantoin increases the effects of preventing skin aging, softening and keeping stratum corneum moisture and preventing and treating chap; the carbomer provided by the invention has the function of protecting the activity of superoxide dismutase as a rheological matrix material; wherein the triethanolamine, the glycerol, the jojoba seed oil, the spermaceti and the glycerin monostearate have an emulsification effect, and the pH value is adjusted simultaneously in the emulsification process, so that the superoxide dismutase is in a conformation state with relatively stable activity.
2. The invention provides a foot massage physiotherapy cream which comprises the following components: (1) the massage cream has the effects of softening skin and increasing skin penetration during massage, so that effective nutrient substances can be more conveniently penetrated into the deep part of the skin; (2) the effective components are applied to the skin in a combined massage manner, so that the effects of caring the skin, softening and moisturizing, preventing chapping, promoting blood circulation and removing blood stasis, relaxing muscles and tendons and relieving pain, relieving fatigue and accelerating blood circulation can be achieved through the massage; (3) compared with traditional Chinese medicine foot bath, the foot bath liquid has better pedicure effect, and has the characteristics of convenience in carrying and use, compound functions, and saving of traditional Chinese medicine resources and cost.
3. The preparation method of the foot massage physiotherapy cream provided by the invention extracts the effective components of the raw materials according to the properties of the effective components, reduces the loss of the effective components of the raw materials to the maximum extent, and the prepared physiotherapy cream has stable components and fine texture.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be described in detail below. It is to be understood that the described embodiments are merely exemplary of the invention, and not restrictive of the full scope of the invention. All other embodiments, which can be derived by a person skilled in the art from the examples given herein without any inventive step, are within the scope of the present invention.
Example 1
A foot massage physiotherapy composition, the composition comprising the following raw materials by weight: 10g of ginseng root, 5g of angelica, 5g of sea buckthorn fruit, 30g of superoxide dismutase, 10g of gastrodia elata, 10g of salvia miltiorrhiza, 5g of red paeony root, 3g of frankincense, 2g of galangal, 2g of cinnamon, 10g of bletilla striata, 7g of rhizoma cibotii, 2g of sodium hyaluronate, 3g of allantoin, 3g of serine, 5g of collagen, 5g of trehalose, 1g of borneol and 882g of water.
Example 2
A foot massage physiotherapy composition, the composition comprising the following raw materials by weight: 70g of ginseng root, 20g of angelica, 20g of sea buckthorn fruit, 100g of superoxide dismutase, 40g of gastrodia elata, 40g of salvia miltiorrhiza, 20g of red paeony root, 15g of frankincense, 10g of galangal, 10g of cinnamon, 70g of bletilla striata, 20g of rhizoma cibotii, 20g of sodium hyaluronate, 20g of allantoin, 20g of serine, 50g of collagen, 15g of trehalose, 5g of borneol and 295g of water.
Example 3
A foot massage physiotherapy composition, the composition comprising the following raw materials by weight: 35g of ginseng root, 7.5g of angelica, 7.5g of sea-buckthorn fruit, 100g of superoxide dismutase, 10g of gastrodia elata, 7.5g of salvia miltiorrhiza, 7.5g of red paeony root, 5g of frankincense, 3g of galangal, 3g of cinnamon, 35g of bletilla striata, 10g of rhizoma cibotii, 5g of sodium hyaluronate, 15g of allantoin, 10g of serine, 15g of collagen, 10g of trehalose, 5g of borneol and 709g of water.
Example 4
The foot massage physiotherapy cream comprises the following raw materials by weight: 10g of ginseng root, 5g of angelica, 5g of sea buckthorn fruit, 30g of superoxide dismutase, 10g of gastrodia elata, 10g of salvia miltiorrhiza, 5g of red paeony root, 3g of frankincense, 2g of galangal, 2g of cinnamon, 10g of bletilla striata, 7g of rhizoma cibotii, 2g of sodium hyaluronate, 3g of allantoin, 3g of serine, 5g of collagen, 50g of glycerol, 10g of jojoba seed oil, 5g of spermaceti, 3g of glyceryl monostearate, 5g of trehalose, 1g of borneol, 2g of carbomer, 10g of triethanolamine and 802g of water.
The preparation method of the foot massage physiotherapy cream comprises the following steps:
(1) weighing ginseng root, Chinese angelica, seabuckthorn fruit, gastrodia elata, red sage root, red paeony root, frankincense, galangal, cinnamon, bletilla and rhizoma cibotii, adding 8 times of water by weight, heating to boil, cooling to 75 ℃, performing heat preservation extraction for 2.5 hours, filtering to obtain a first filtrate, adding 6 times of water by weight into filter residue, heating to boil, cooling to 75 ℃, performing heat preservation extraction for 1.5 hours, filtering to obtain a second filtrate, adding 4 times of water by weight into the filter residue, heating to boil, cooling to 75 ℃, performing heat preservation extraction for 0.5 hour, filtering to obtain a third filtrate, combining the first filtrate, the second filtrate and the third filtrate to obtain a mixed filtrate, standing for precipitation, filtering, and concentrating until the weight ratio of the raw material amount to the water is 1:1 to obtain a mixed herbal extracting solution;
(2) weighing carbomer, adding 30 times of water, soaking for 2 days, sequentially adding trehalose and glycerol, stirring, and sterilizing at 112 deg.C for 30min to obtain base solution;
(3) preparing a mixed solution: weighing superoxide dismutase and sodium hyaluronate, adding 1 time of water, uniformly mixing, filtering, and sterilizing the uniformly mixed superoxide dismutase and sodium hyaluronate solution by using a microporous filter membrane, wherein the pore diameter of the microporous filter membrane is 0.2 mu m to obtain a mixed solution;
(4) adding the mixed extract of the herbal medicines obtained in the step (1), the mixed solution obtained in the step (3), allantoin, serine, collagen, jojoba seed oil, spermaceti wax, glyceryl monostearate, triethanolamine and borneol into the base solution obtained in the step (2), adding water until the total weight of the raw materials and the water is 1000g, stirring and mixing at 30 ℃ until the mixture is uniform, and sealing and emulsifying for 24h to obtain the foot massage physical therapy cream.
Example 5
The foot massage physiotherapy cream comprises the following raw materials by weight: 70g of ginseng root, 20g of angelica, 20g of sea buckthorn fruit, 100g of superoxide dismutase, 40g of gastrodia elata, 40g of salvia miltiorrhiza, 20g of red paeony root, 15g of frankincense, 10g of galangal, 10g of cinnamon, 70g of bletilla striata, 20g of rhizoma cibotii, 20g of sodium hyaluronate, 20g of allantoin, 20g of serine, 50g of collagen, 200g of glycerol, 50g of jojoba seed oil, 30g of spermaceti, 15g of glyceryl monostearate, 15g of trehalose, 5g of borneol, 6g of carbomer, 50g of triethanolamine and 84g of water.
The preparation method of the foot massage physiotherapy cream comprises the following steps:
(1) weighing ginseng root, Chinese angelica, seabuckthorn fruit, gastrodia elata, salvia miltiorrhiza, red paeony root, frankincense, galangal, cinnamon, bletilla and rhizoma cibotii, adding 10 times of water by weight, heating to boil, cooling to 85 ℃, carrying out heat preservation extraction for 3.5 hours, filtering to obtain a first filtrate, adding 8 times of water by weight into filter residue, heating to boil, cooling to 85 ℃, carrying out heat preservation extraction for 2.5 hours, filtering to obtain a second filtrate, adding 6 times of water by weight into the filter residue, heating to boil, cooling to 85 ℃, carrying out heat preservation extraction for 1.5 hours, filtering to obtain a third filtrate, combining the first filtrate, the second filtrate and the third filtrate to obtain a mixed filtrate, standing and precipitating at 6 ℃, taking supernatant, sieving with a 100-mesh sieve, concentrating until the weight ratio of the raw material amount to the water is 1:1.5, and obtaining a herbal mixed extract;
(2) weighing carbomer, adding 40 times of water, soaking for 5 days, sequentially adding trehalose and glycerol, stirring, and sterilizing at 122 deg.C for 20min to obtain base solution;
(3) preparing a mixed solution: weighing superoxide dismutase and sodium hyaluronate, adding 4 times of water by weight, uniformly mixing, filtering, and sterilizing the uniformly mixed superoxide dismutase and sodium hyaluronate solution by using a microporous filter membrane, wherein the pore diameter of the microporous filter membrane is 0.22 mu m to obtain a mixed solution;
(4) adding the mixed extract of the herbal medicine obtained in the step (1), the mixed solution obtained in the step (3), allantoin, serine, collagen, jojoba seed oil, spermaceti wax, glyceryl monostearate, triethanolamine and borneol into the base solution obtained in the step (2), adding water until the total weight of the raw materials and the water is 1000g, stirring and mixing at 45 ℃ until the mixture is uniform, and sealing and emulsifying for 48h to obtain the foot massage physical therapy cream.
Example 6
The foot massage physiotherapy cream comprises the following raw materials by weight: 10g of ginseng root, 5g of angelica, 5g of sea buckthorn fruit, 30g of superoxide dismutase, 10g of gastrodia elata, 10g of salvia miltiorrhiza, 5g of red paeony root, 3g of frankincense, 2g of galangal, 2g of cinnamon, 10g of bletilla striata, 7g of rhizoma cibotii, 2g of sodium hyaluronate, 3g of allantoin, 3g of serine, 5g of deer bone collagen, 2g of carbomer, 50g of glycerol, 10g of triethanolamine, 10g of jojoba seed oil, 5g of spermaceti, 3g of glycerin monostearate, 5g of trehalose, 1g of borneol and 802g of deionized water.
The preparation method of the foot massage physiotherapy cream comprises the following steps:
(1) preparing a herbal mixed extract: weighing ginseng root, Chinese angelica, seabuckthorn fruit, gastrodia elata, red sage root, red paeony root, frankincense, galangal, cinnamon, bletilla and rhizoma cibotii, adding 9 times of water by weight, heating to boil, cooling to 80 ℃, performing heat preservation extraction for 3 hours, filtering to obtain a first filtrate, adding 7 times of water by weight into filter residue, heating to boil, cooling to 80 ℃, performing heat preservation extraction for 2 hours, filtering to obtain a second filtrate, adding 5 times of water by weight into the filter residue, heating to boil, cooling to 80 ℃, performing heat preservation extraction for 1 hour, filtering to obtain a third filtrate, combining the first filtrate, the second filtrate and the third filtrate to obtain a mixed filtrate, standing for precipitation, taking a supernatant, sieving with a 200-mesh sieve, and concentrating until the weight ratio of the raw material to the water is 1:1 to obtain a mixed herbal extracting solution;
(2) preparing a base liquid: weighing carbomer, adding 35 times of water, soaking for 4 days, sequentially adding trehalose and glycerol, stirring, and sterilizing at 115 deg.C for 25min to obtain base solution;
(3) preparing a mixed solution: weighing superoxide dismutase and sodium hyaluronate, adding 2 times of water by weight, uniformly mixing, filtering, and sterilizing the uniformly mixed superoxide dismutase and sodium hyaluronate solution by using a microporous filter membrane, wherein the pore diameter of the microporous filter membrane is 0.16 mu m to obtain a mixed solution;
(4) adding the mixed extract of the herbal medicine obtained in the step (1), the mixed solution obtained in the step (3), allantoin, serine, collagen, jojoba seed oil, spermaceti wax, glyceryl monostearate, triethanolamine and borneol into the base solution obtained in the step (2), adding water until the total weight of the raw materials and the water is 1000g, stirring and mixing at 40 ℃ until the mixture is uniform, and sealing and emulsifying for 30h to obtain the foot massage physical therapy cream.
Example 7
The foot massage physiotherapy cream comprises the following raw materials by weight: 50g of ginseng root, 15g of angelica, 15g of sea buckthorn fruit, 100g of superoxide dismutase, 30g of gastrodia elata, 30g of salvia miltiorrhiza, 15g of red paeony root, 10g of frankincense, 8g of galangal, 8g of cinnamon, 60g of bletilla striata, 15g of rhizoma cibotii, 15g of sodium hyaluronate, 15g of allantoin, 15g of serine, 50g of deer bone collagen, 6g of carbomer, 200g of glycerol, 50g of triethanolamine, 50g of jojoba seed oil, 30g of spermaceti, 15g of glyceryl monostearate, 15g of trehalose, 5g of borneol and 168g of deionized water.
The preparation method of the foot massage physiotherapy cream comprises the following steps:
(1) preparing a herbal mixed extract: weighing ginseng root, Chinese angelica, seabuckthorn fruit, gastrodia elata, red sage root, red paeony root, frankincense, galangal, cinnamon, bletilla and rhizoma cibotii, adding 9 times of water by weight, heating to boil, cooling to 80 ℃, performing heat preservation extraction for 3 hours, filtering to obtain a first filtrate, adding 7 times of water by weight into filter residue, heating to boil, cooling to 80 ℃, performing heat preservation extraction for 2 hours, filtering to obtain a second filtrate, adding 5 times of water by weight into the filter residue, heating to boil, cooling to 80 ℃, performing heat preservation extraction for 1 hour, filtering to obtain a third filtrate, combining the first filtrate, the second filtrate and the third filtrate to obtain a mixed filtrate, standing at 10 ℃, precipitating, filtering and concentrating until the weight ratio of the raw material to the water is 1:1 to obtain a mixed herbal extract;
(2) preparing a base liquid: weighing a rheological regulator, adding 35 times of water by weight, soaking for 4 days, then sequentially adding trehalose and glycerol, stirring uniformly, and sterilizing at 115 ℃ for 25min to obtain a base solution;
(3) preparing a mixed solution: weighing superoxide dismutase and sodium hyaluronate, adding 3 times of water by weight, uniformly mixing, filtering, and sterilizing the uniformly mixed superoxide dismutase and sodium hyaluronate solution by using a microporous filter membrane, wherein the pore diameter of the microporous filter membrane is 0.22 mu m to obtain a mixed solution;
(4) adding the mixed extract of the herbal medicines obtained in the step (1), the mixed solution obtained in the step (3), allantoin, serine, collagen, jojoba seed oil, spermaceti wax, glyceryl monostearate, triethanolamine and borneol into the base solution obtained in the step (2), adding water until the total weight of the raw materials and the water is 1000g, stirring and mixing at 40 ℃ until the mixture is uniform, and sealing and emulsifying for 30h to obtain the foot massage physical therapy cream.
Test examples
The beneficial effects of the present invention are illustrated below in connection with clinical trial data:
1. general data of the testers
Selecting 25 patients with rhagadia manus et pedis; 15 patients with symptoms of easy skin stagnation and cold hands and feet caused by poor blood circulation.
2. The foot massage physiotherapy cream obtained according to example 5 was used once a day. When the foot massage physiotherapy cream is used, hands and feet are soaked in hot water, then the foot massage physiotherapy cream obtained in the embodiment 5 is used for massaging the hands or the feet for 10-15min, two weeks are continuously used as a treatment course, 2-5 treatment courses are continuously carried out, and the application is stopped if the hands or the feet are cured.
3. Determination of Effect
The method has the following advantages: after 2-3 treatment courses, the skin of a patient with rhagadia manus et pedis is intact, the skin with poor blood circulation is dark, the skin is not silted, or the area of the silted skin is reduced by more than half, the cold condition of the hands and feet is not appeared or is obviously improved, other accompanying symptoms disappear or are reduced, and no adverse reaction exists;
and (4) invalidation: after 2-3 treatment courses, the symptoms and clinical signs are not improved or aggravated, and other objective examination indexes are not improved or aggravated.
Effective rate is 100% of effective people/total people
4. Results of use
After 2-3 treatment courses, the effective number of 25 patients with rhagades of hands and feet is 24, and the effective rate is 96%; the effective number of 15 patients with poor blood circulation is 14, and the effective rate is 93.3%. The total effective rate is 38/40 × 100% ═ 95%.
The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and all the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.

Claims (8)

1. The foot massage physiotherapy cream is characterized by being prepared from the following raw materials in 1000 parts by weight: 10-70 parts of ginseng root, 5-20 parts of angelica, 5-20 parts of sea buckthorn fruit, 30-100 parts of superoxide dismutase, 10-40 parts of gastrodia elata, 10-40 parts of salvia miltiorrhiza, 5-20 parts of red paeony root, 3-15 parts of frankincense, 2-10 parts of galangal, 2-10 parts of cinnamon, 10-70 parts of bletilla striata, 7-20 parts of rhizoma cibotii, 2-20 parts of sodium hyaluronate, 3-20 parts of allantoin, 3-20 parts of serine, 5-50 parts of collagen, 5-15 parts of trehalose, 1-5 parts of borneol, 2-6 parts of carbomer, 10-50 parts of triethanolamine, 50-200 parts of glycerol, 10-50 parts of jojoba seed oil, 5-30 parts of spermaceti and 3-15 parts of glyceryl monostearate, and the balance of water;
the preparation method of the foot massage physiotherapy cream comprises the following steps:
(1) preparing a herbal mixed extract: weighing ginseng root, angelica, seabuckthorn fruit, gastrodia elata, salvia miltiorrhiza, red paeony root, frankincense, galangal, cinnamon, bletilla and rhizoma cibotii, adding 8-10 times of water by weight, heating to boil, cooling to 75-85 ℃, carrying out heat preservation extraction for 2.5-3.5h, filtering to obtain a first filtrate, adding 6-8 times of water by weight into filter residue, heating to boil, cooling to 75-85 ℃, carrying out heat preservation extraction for 1.5-2.5h, filtering to obtain a second filtrate, adding 4-6 times of water by weight into the filter residue, heating to boil, cooling to 75-85 ℃, carrying out heat preservation extraction for 0.5-1.5h, filtering to obtain a third filtrate, combining the first filtrate, the second filtrate and the third filtrate to obtain a mixed filtrate, standing for precipitation, filtering and concentrating to obtain a mixed herbal extracting solution;
(2) preparing a base liquid: weighing carbomer, adding 30-40 times of water, soaking, sequentially adding trehalose and glycerol, stirring, and sterilizing to obtain base solution;
(3) preparing a mixed solution: weighing superoxide dismutase and sodium hyaluronate, adding 1-4 times of water, mixing, filtering, and sterilizing to obtain mixed solution;
(4) adding the mixed herbal extract obtained in the step (1), the mixed solution obtained in the step (3), allantoin, serine, collagen, jojoba seed oil, spermaceti, glyceryl monostearate, triethanolamine and borneol into the base solution obtained in the step (2), adding water until the total weight of the raw materials and the water is 1000 parts, stirring and mixing uniformly, and sealing and emulsifying for 24-48h to obtain the foot massage physical therapy cream.
2. The preparation method of the foot massage physiotherapy cream as set forth in claim 1, which comprises the steps of: (1) preparing a herbal mixed extract: weighing ginseng root, angelica, seabuckthorn fruit, gastrodia elata, salvia miltiorrhiza, red paeony root, frankincense, galangal, cinnamon, bletilla and rhizoma cibotii, adding 8-10 times of water by weight, heating to boil, cooling to 75-85 ℃, carrying out heat preservation extraction for 2.5-3.5h, filtering to obtain a first filtrate, adding 6-8 times of water by weight into filter residue, heating to boil, cooling to 75-85 ℃, carrying out heat preservation extraction for 1.5-2.5h, filtering to obtain a second filtrate, adding 4-6 times of water by weight into the filter residue, heating to boil, cooling to 75-85 ℃, carrying out heat preservation extraction for 0.5-1.5h, filtering to obtain a third filtrate, combining the first filtrate, the second filtrate and the third filtrate to obtain a mixed filtrate, standing for precipitation, filtering and concentrating to obtain a mixed herbal extracting solution; (2) preparing a base liquid: weighing carbomer, adding 30-40 times of water, soaking, sequentially adding trehalose and glycerol, stirring, and sterilizing to obtain base solution; (3) preparing a mixed solution: weighing superoxide dismutase and sodium hyaluronate, adding 1-4 times of water, mixing, filtering, and sterilizing to obtain mixed solution; (4) adding the mixed herbal extract obtained in the step (1), the mixed solution obtained in the step (3), allantoin, serine, collagen, jojoba seed oil, spermaceti, glyceryl monostearate, triethanolamine and borneol into the base solution obtained in the step (2), adding water until the total weight of the raw materials and the water is 1000 parts, stirring and mixing uniformly, and sealing and emulsifying for 24-48h to obtain the foot massage physical therapy cream.
3. The method for preparing foot massage physiotherapy cream as claimed in claim 2, wherein in the step (1), the supernatant of the mixed filtrate to be settled is filtered through a 100-200 mesh sieve.
4. The method for preparing foot massage physiotherapy cream according to claim 2, wherein in the step (1), the raw materials are concentrated until the weight ratio of the raw materials to the water is 1: 1-1.5.
5. The method for preparing foot massage physiotherapy cream according to claim 2, wherein in the step (2), the soaking time is 2-5 days.
6. The preparation method of the foot massage physiotherapy cream as claimed in claim 2, wherein in the step (2), the sterilization temperature is 112-122 ℃, and the sterilization time is 20-30 min.
7. The method for preparing foot massage physiotherapy cream as claimed in claim 2, wherein in the step (3), the superoxide dismutase and the sodium hyaluronate which are uniformly mixed are sterilized by using a microporous membrane, and the pore diameter of the microporous membrane is not more than 0.22 μm.
8. The method for preparing foot massage physiotherapy cream according to claim 2, wherein in the step (4), the stirring temperature is 30-45 ℃.
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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106265363A (en) * 2016-09-29 2017-01-04 窦靖鑫 A kind of ferment disposable sleep mask of book on Chinese herbal medicine and preparation method thereof
CN106619186A (en) * 2017-01-20 2017-05-10 吉林省拓华生物科技有限公司 Preparation for protecting activity of superoxide dismutase (SOD) and preparation method of preparation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106265363A (en) * 2016-09-29 2017-01-04 窦靖鑫 A kind of ferment disposable sleep mask of book on Chinese herbal medicine and preparation method thereof
CN106619186A (en) * 2017-01-20 2017-05-10 吉林省拓华生物科技有限公司 Preparation for protecting activity of superoxide dismutase (SOD) and preparation method of preparation

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