CN107410370A - 一种灭蚊剂 - Google Patents
一种灭蚊剂 Download PDFInfo
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- CN107410370A CN107410370A CN201710435649.XA CN201710435649A CN107410370A CN 107410370 A CN107410370 A CN 107410370A CN 201710435649 A CN201710435649 A CN 201710435649A CN 107410370 A CN107410370 A CN 107410370A
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- 239000009910 sargent gloryvine Substances 0.000 claims abstract description 16
- 239000000284 extract Substances 0.000 claims abstract description 12
- 239000004480 active ingredient Substances 0.000 claims abstract description 10
- LNIMMWYNSBZESE-UHFFFAOYSA-N 2-Ethyl-3-methylpyrazine, 9CI Chemical class CCC1=NC=CN=C1C LNIMMWYNSBZESE-UHFFFAOYSA-N 0.000 claims description 15
- KYQCOXFCLRTKLS-UHFFFAOYSA-N Pyrazine Chemical compound C1=CN=CC=N1 KYQCOXFCLRTKLS-UHFFFAOYSA-N 0.000 claims 2
- -1 2- ethyl Chemical group 0.000 claims 1
- PCNDJXKNXGMECE-UHFFFAOYSA-N Phenazine Natural products C1=CC=CC2=NC3=CC=CC=C3N=C21 PCNDJXKNXGMECE-UHFFFAOYSA-N 0.000 claims 1
- CAWHJQAVHZEVTJ-UHFFFAOYSA-N methylpyrazine Chemical compound CC1=CN=CC=N1 CAWHJQAVHZEVTJ-UHFFFAOYSA-N 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 241000255925 Diptera Species 0.000 description 12
- 230000000694 effects Effects 0.000 description 12
- 239000000077 insect repellent Substances 0.000 description 11
- 239000007788 liquid Substances 0.000 description 6
- 238000012360 testing method Methods 0.000 description 4
- 230000008029 eradication Effects 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 230000007774 longterm Effects 0.000 description 3
- 239000000779 smoke Substances 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 241000607479 Yersinia pestis Species 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 235000019504 cigarettes Nutrition 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- 239000006200 vaporizer Substances 0.000 description 2
- 241000238631 Hexapoda Species 0.000 description 1
- 206010035148 Plague Diseases 0.000 description 1
- 208000005374 Poisoning Diseases 0.000 description 1
- 208000037386 Typhoid Diseases 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 238000009534 blood test Methods 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002147 killing effect Effects 0.000 description 1
- 201000004792 malaria Diseases 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 239000013618 particulate matter Substances 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 230000000391 smoking effect Effects 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 201000008297 typhoid fever Diseases 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/60—1,4-Diazines; Hydrogenated 1,4-diazines
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Agronomy & Crop Science (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
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- Biotechnology (AREA)
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- Natural Medicines & Medicinal Plants (AREA)
- Pest Control & Pesticides (AREA)
- Catching Or Destruction (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
本发明公开了一种灭蚊剂，有效成分包括2‑乙基‑3‑甲基吡嗪与红藤提取液。本发明的灭蚊剂，不会对人和动物造成伤害，安全，高效。
Description
技术领域
本发明涉及一种灭蚊剂，属于生活用品领域。
背景技术
蚊虫是世界上重要的卫生害虫，可以传播疟疾、鼠疫等流行病，严重威胁着人们的生命安全。
传统的盘式蚊香燃烧的烟里，可能会含有对人体危害的物质：超细微粒（直径小于2.5微米的颗粒物质）。有研究报道称，点一盘蚊香放出的微粒和烧4包香烟的量相当，因此长期使用可能会对人体造成伤寒，例如诱发哮喘等。而油基型气雾剂，在使用的过程中，会在物体的表面留下油渍，对环境的污染也比较严重。在运输过程中也有隐患。因此，提供一种安全，可靠的液体蚊香成为一个市场需求。
发明内容
针对上述存在的问题，本发明的目的是提供一种灭蚊剂，灭蚊效果好，无毒。
为了实现上述目的，本发明采用的技术方案是：一种灭蚊剂，有效成分包括2-乙基-3-甲基吡嗪与红藤提取液。
所述的红藤提取液与2-乙基-3-甲基吡嗪比例在20-30:1。
所述有效成分占总质量的1%-20%。
本发明有效成分包括2-乙基-3-甲基吡嗪与红藤提取液，具有而非常好的灭蚊效果。
具体实施方式
本发明中的比值均为质量比。
灭蚊剂有效成分为：2-乙基-3-甲基吡嗪与红藤提取液,
红藤提取液与2-乙基-3-甲基吡嗪的质量比为20:1。
2-乙基-3-甲基吡嗪CAS:15707-23-0,
红藤提取液制备方法如下：将2份粉碎的干燥红藤加入到25份的水中，采用油浴加热方式以沸水回流提取溶液，经离心分离，得到上层清液即为红藤提取液。
A、红藤提取液，B、2-乙基-3-甲基吡嗪,有效成分占5%，其余为离子水。
对不同含量的有效成分液体蚊香进行室内药效测试，采用GB18418-2009家用卫生杀虫用品电热液体蚊香标准，进行测试。在该标准中，KT50值(方箱法)≤10分钟即可判为合格，时间越短说明对蚊虫驱杀效果越好，测试数据见表。
上述实验结果可以看出红藤提取液与2-乙基-3-甲基吡嗪单一作为有效成分灭蚊效果不是很理想，而二者的混合液对于灭蚊效果有一定效果，但效果不显著，但当红藤提取液与2-乙基-3-甲基吡嗪比例在20-30:1这一区间有着非常好的灭蚊效果，特别是红藤提取液与2-乙基-3-甲基吡嗪比例在25:1时，有着惊人的灭蚊效果，灭蚊性能大幅度提高，具有意想不到的灭蚊效果。
毒性测试：
对红藤提取液与2-乙基-3-甲基吡嗪比例在25:1这一组的灭蚊剂进行毒性测试，参照国家卫生部《职业性急性化学物中毒性血液系统疾病诊断标准》及《中药、天然药物免疫毒性研究的技术指导原则》标准，制定本发明测试例。
实验种类：两只幼龄小白鼠。
实验方法：
(1)实验条件：实验室温度(27±2)℃
(2)实验装置：在两个25平方米相同温度的实验室内，各放置一个大小相同规格的80×80×80cm细密透气的网状笼罩。
(3)实验步骤：将两只幼龄小白鼠分开各放于两个实验室的网状笼罩内，并分成对照组和薰本发明蚊香组，分别给予不薰本发明蚊香和薰本发明蚊香，测量幼龄小白鼠体重，观察血液学生化学指标、组织病理学变化及停止薰本发明蚊香后的恢复情况等。放置本发明蚊香时要安装在网状笼罩内离底30厘米处。给药剂量：电加热灭蚊剂，保持24小时长期使用。时间：连续使用一个月，观察对照组和薰本发明蚊香组的幼龄小白鼠，长期使用本发明蚊香对幼龄小白鼠的毒性及副作用。清洁：笼罩内两天清洁一次。
结果：两只幼龄小白鼠抽血化验后，各项生化指标均为正常，表明本发明蚊香对幼龄小白鼠无毒副作用，只有超过24小时室内蚊香烟雾太浓时，需开窗换气10-15分钟，抽血前8小时未给两幼龄小白鼠进食。
结论：长期使用本发明灭蚊剂对幼龄小白鼠无任何毒性。
Claims (3)
1.一种灭蚊剂，有效成分包括2-乙基-3-甲基吡嗪与红藤提取液。
2.根据权利要求1所述的一种灭蚊剂，其特征在于，所述的红藤提取液与2-乙基-3-甲基吡嗪比例在20-30:1。
3.根据权利要求1所述的一种灭蚊剂，其特征在于，所述有效成分占总质量的1%-20%。
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101766192A (zh) * | 2007-12-06 | 2010-07-07 | 北京农学院 | 贯众植物性杀螨剂及其制备方法 |
| CN104918488A (zh) * | 2012-08-17 | 2015-09-16 | 欧菲克特实验室公司 | 用于引诱和驱避昆虫的组合物和方法 |
| CN106177692A (zh) * | 2016-09-19 | 2016-12-07 | 扬中牧乐药业有限公司 | 一种驱除猪肠道寄生虫的中草药提取物制剂的制备方法 |
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2017
- 2017-06-11 CN CN201710435649.XA patent/CN107410370A/zh active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101766192A (zh) * | 2007-12-06 | 2010-07-07 | 北京农学院 | 贯众植物性杀螨剂及其制备方法 |
| CN104918488A (zh) * | 2012-08-17 | 2015-09-16 | 欧菲克特实验室公司 | 用于引诱和驱避昆虫的组合物和方法 |
| CN106177692A (zh) * | 2016-09-19 | 2016-12-07 | 扬中牧乐药业有限公司 | 一种驱除猪肠道寄生虫的中草药提取物制剂的制备方法 |
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