CN107405622A - Pipe holder instrument - Google Patents
Pipe holder instrument Download PDFInfo
- Publication number
- CN107405622A CN107405622A CN201680011997.8A CN201680011997A CN107405622A CN 107405622 A CN107405622 A CN 107405622A CN 201680011997 A CN201680011997 A CN 201680011997A CN 107405622 A CN107405622 A CN 107405622A
- Authority
- CN
- China
- Prior art keywords
- pipe
- pipe holder
- base portion
- support
- instrument
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/06—Test-tube stands; Test-tube holders
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
- B01L3/50855—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates using modular assemblies of strips or of individual wells
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/06—Test-tube stands; Test-tube holders
- B01L9/065—Test-tube stands; Test-tube holders specially adapted for capillary tubes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
- B01L9/523—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for multisample carriers, e.g. used for microtitration plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
- B01L9/527—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for microfluidic devices, e.g. used for lab-on-a-chip
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L99/00—Subject matter not provided for in other groups of this subclass
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/021—Adjust spacings in an array of wells, pipettes or holders, format transfer between arrays of different size or geometry
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/025—Align devices or objects to ensure defined positions relative to each other
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/04—Exchange or ejection of cartridges, containers or reservoirs
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0848—Specific forms of parts of containers
- B01L2300/0851—Bottom walls
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/12—Specific details about materials
- B01L2300/123—Flexible; Elastomeric
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/54—Supports specially adapted for pipettes and burettes
- B01L9/543—Supports specially adapted for pipettes and burettes for disposable pipette tips, e.g. racks or cassettes
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Dispersion Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Devices For Use In Laboratory Experiments (AREA)
- Cleaning In General (AREA)
- Supports For Pipes And Cables (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
A kind of tool and method for multiple pipes to be removed from pipe holder is provided.Pipe holder instrument includes base portion and/or receives the top part of pipe holder.Base portion has support surface, and the support surface is used for the bottom for engaging the closing of multiple pipes.The support surface can be curved so that pipe holder is waved so that multiple pipes to be discharged from support around the support surface of bending.Top part can be configured to engagement support so that applying pressure on support along the pressure in support surface direction on top part, without applying pressure to pipe.The pipe is discharged due to being pressurized from support.The element of pipe holder instrument is also configured to the pipe in the support or lid being fixed on pipe.
Description
The cross reference of related application
It is " pipe removing tool (Tube Removal Tool) " this application claims the theme submitted for 24th for 2 months in 2015
The priority of 62/120, No. 173 U.S. Provisional Application, entire contents are incorporated by reference into the application.
Technical field
Embodiments of the invention relate generally to the pipe holder instrument that multiple pipes are discharged from pipe holder, more specifically, relating to
And the pipe holder instrument of multiple pipes is synchronously discharged from pipe holder, and the method using the pipe holder instrument.
Background technology
Microtiter plate is the flat board for having multiple " wells ", as small test tube or for receiving tube wherein.Microtitration
Plate has turned into the conventional tool of analysis and research and clinical diagnosis testing laboratory.Microtiter plate generally has with 2：3 matrixes are arranged
6,24,96,384,1536,6144 or 24576 sample wells of row.Although it is most common with 96 wells of 8 × 12 spread configurations
, but still there are some microtiter plates to manufacture 3456 wells even 9600 wells.
Depending on size, each well generally remains the solid-like of the liquid or equivalent between about several nanoliters to hundreds of milliliters
Product (such as dry powder).Therefore, some plates have the well with closed bottom.In certain embodiments, plate can be configured to support with
Support glass or plastic tube or pipe strip insert.In these embodiments, well alternately has unlimited bottom.It is exemplary
The cross section of well can be circular (including cylinder or cone) or square.Have been developed for carrying out pipette (example
Such as, multichannel pipette) liquid of measurement is disposably pipetted into entire row well.Have been developed for for various laboratories
PCR equipment and Other Instruments are to receive standard-sized microtiter plate and handle the sample being included in well.Many companies
Even develop dedicated for handling the robot of microtiter plate.
Generally, microtiter plate is provided with the well to be formed in plate.Most common manufacture method is injection molding, is generally used
In polystyrene, polypropylene and cycloolefin.However, micro- shape plate can be made up of various polymer, as long as this polymer is suitable to warp
By wide temperature range and there is chemical resistance.
Recently, more plates are made available by, and it is 12 that these plates, which include support and multiple or respective pipe, common construction,
8 pipes (twelve strips of eight tubes) of bar every or 8 every 12 pipes.It is such to be arranged such that single
Become easier in plate using the smaller reaction group of a part of plate or preparation.Generally, the interval of pipe causes 96 well type microtitrations
The normal space of the well of plate, once assembled, support and pipe just compatible with various instrument and instrument, these instruments and instrument
Have been developed for come to be used together with microtiter plate.
By taking support and pipe as an example, i.e. Loborack-96 (Micronic North America, McMurray, PA).Example
Such as, Loborack-96 can be kept in the construction of 96 well type 96 individually pipe (for example, 0.50ml or 0.75ml pipe), 8
Every 12 pipes or 12 every 8 pipes.Each pipe can be individually capped, or each with one 8 or 12 lid cappings respectively
Bar.Although pipe is disposable and means the article being intended for single use, support can be reused.However, manually by pipe from
It is highly difficult to be removed in support, and is typically what is opened when pipe is removed, it is likely that pollutes the content or spilling of pipe
Harmful or polluter.Although Micronic sale once removes the instrument of a pipe, there is still a need for quickly and easily
Remove the instrument of multi coil or all pipes.
The content of the invention
In the scheme of the present invention, there is provided a kind of pipe holder instrument, the pipe holder instrument include being used for receiving tube
The base portion (exemplarily, pipe holder includes support and the multiple pipes being arranged in the support) of support, the base portion, which has, to be used to connect
The surface of pipe is closed, the pressure on its medium-height trestle makes multiple pipes discharge (dislodge) from the support.For example, in some embodiments
In, multiple pipes can be discharged (for example, in time) from support simultaneously, in real time, synchronously and/or immediately in order.
In at least one embodiment, pipe holder can be located on the top on surface so that the surface and the bottom (for example, blind end) of multiple pipes
Engagement, alternatively, the pipe holder does not engage with least a portion of support so that substantially or at least partially downward on support
Power (for example, pressure) multiple pipes are discharged from support.In certain embodiments, pipe holder instrument may also include top part,
The top part is configured to the applying power at least a portion of support.Multiple surfaces and/or other constructions are provided for pipe branch
Frame instrument.
In another arrangement, there is provided a kind of pipe holder instrument, it includes：Top part, for receiving pipe holder wherein；With
Base portion, there is the surface for being used for engaging with multiple pipes in pipe holder, the pressure in (for example, direction along surface) wherein on top part
Power discharges multiple pipes from support.
In yet another aspect, there is provided a kind of method that multiple pipes are removed from the pipe holder with support and sleeve,
Methods described includes pipe holder being placed in base portion, and the base portion has the surface for being used for engaging multiple pipes in pipe holder,
And apply pressure on support so that multiple pipes to be discharged from support.
The supplementary features and advantage of the embodiment of the present invention will in the following description propose or can be from the implementations of the present invention
Middle understanding.Pass through the instrument particularly pointed out in appended claims and combination, it is possible to achieve and obtain these implementations of the present invention
The feature and advantage of example.These and other feature will be described hereinafter become more to show in the description of book and appended claims and
It is clear to, or can be understood by these examples for implementing to be presented below.
Brief description of the drawings
In order to describe to obtain the mode of above and other advantages and feature of the present invention, the specific implementation shown in refer to the attached drawing
Content described briefly above is explained in more detail example.It should be understood that the typical case that these accompanying drawings depict only the present invention is real
Example is applied, so being not considered as restriction on its scope, the present invention is carried out by supplementary features and details by the use of accompanying drawing
Describe and explain, wherein：
Fig. 1 is the stereogram for the base portion of exemplary tube support instrument；
Fig. 2 is the stereogram for the top part being used together with Fig. 1 base portion；
Fig. 3 is the exploded perspective view of the pipe holder inserted between Fig. 1 base portion and Fig. 2 top part；
Fig. 4 is the viewgraph of cross-section of the pipe holder inserted between Fig. 1 base portion and Fig. 2 top part；
Fig. 5 is similar to Fig. 4, except the pressure applied on the top part and removed from support some
Pipe；
Fig. 6 is similar to Fig. 1, except showing the base portion for different exemplary tube support instruments；
Fig. 7 is similar to Fig. 2, the top part except showing the exemplary tube support instrument for replacement；
Fig. 8 is similar to Fig. 5, base portion and top part except showing the exemplary pipe holder instrument for replacement；
Fig. 9 is Fig. 8 base portion and the top view of top part；
Figure 10 shows the comb with lid, and is positioned to apply stressed top part to lid；
Figure 11 is similar to FIG. 10, is in except covering by the pressure from top part and the process of (seat) of taking a seat；
Figure 12 is with the comb covered and the viewgraph of cross-section for being oriented to apply stressed inverted base portion to lid；
Figure 13 is similar to Figure 12, except covering in the process taken a seat by the pressure from inverted base portion.
Embodiment
Before embodiment is described in detail, it should be appreciated that the invention is not restricted to the system of specific example, side
Method, equipment, product, process, the parameter of composition and/or external member, certainly, these parameters are transformable.It is to be further understood that
Technical term used herein is only used for the specific embodiment of the description present invention, is not intended to limit the invention in any way
Protection domain.Therefore, although being described in detail with reference to specific configuration to the present invention, description is merely exemplary
, and should not be construed as limiting scope of the present invention.For example, some embodiments may include than in accompanying drawing
The less or additional part of shown and/or written description.In addition, spirit of the invention defined by the claims is not being departed from
On the premise of scope, various remodeling can be carried out to shown construction.Therefore, although herein to the various sides of the present invention
Case, embodiment and/or embodiment are described, but should also be as expecting other schemes, embodiment and embodiment.
Unless otherwise defined, otherwise all technologies used herein and scientific terminology all has and those skilled in the art
It is generally understood that identical implication.Implement this hair with similar or equivalent a variety of methods described herein and material although can use
It is bright, but some exemplary materials and method are only described herein.
The various technical sides such as equipment, system, method are included to the present invention with reference to one or more illustrative embodiments
Case is described.As described herein, term " exemplary " refers to " being used as example, example or description ", and should not be construed
To be more preferably or more favourable than other embodiments disclosed in this invention.In addition, the reference bag of " embodiment " to the present invention
The reference to one or more specific embodiments is included, vice versa, and is intended to not limit the scope of the invention (by appended right
It is required that rather than description below content instruction) on the premise of exemplary embodiment is provided.
It should be noted that as used in the specification and the appended claims, unless otherwise expressly indicated,
Otherwise "one" and "the" of singulative include plural referents.Thus, for example, refer to " tile (tile) " include one, two
Individual or more tile.Similarly, except non-content and/or context clearly dictate otherwise, otherwise refer to that multiple indicants should be explained
It is to include single indicant and/or multiple indicants.Therefore, refer to that " multiple tiles " is not necessarily required to multiple such tiles.
Alternatively, it will be appreciated that one or more tiles should be considered independently of association (conjugation) herein.
As used in text of the statement, word " energy " and " can with " (that is, be meant with potential with the meaning of permission
) rather than the compulsory use that looks like and (that is, mean necessary).In addition, wording " comprising ", " having ", " being related to ", "comprising",
The similar wording that " being characterised by " etc. and specification include used in claims should be containing and/or opening,
There should be the identical meaning as word " comprising " and its modification, and exclude additional, unreferenced element or method step
Suddenly.
As it is used herein, direction and/or any term, for example, " top ", " bottom ", "left", "right", " on ", " under ",
" higher ", " relatively low ", " interior ", " outer ", " internal ", " outside ", " inside ", " outside ", " near-end ", " distal end " and
Similar expression can be individually used for indicating relative direction and/or orientation and being not intended to limit the present invention includes specification, accompanying drawing
And/or the scope of claim.
Can be by describing the component for combining, couple, be attached, connecting and/or being bonded together to illustrate the present invention's
Each technical scheme.As it is used herein, term " with reference to ", " connection ", " attachment ", " connection " and/or " engagement " instruction two
Direct correlation between individual component, or, at the appropriate time, instruction makes indirect association each other by intervention or intermediate module.Phase
Instead, " connect when component and another component " directly in conjunction with ", " directly coupling ", " directly attachment ", " being directly connected to " and/or directly
Close " when, it is not present or does not consider intervening element.
It is to be further understood that without departing from the scope of the invention, embodiments described herein can
To be used in combination with any other described or disclosed embodiment.Therefore, institute according to some embodiments of the present invention
Product, component, element, unit, system, method, technique, composition and/or the external member stated are not departing from the scope of the invention
In the case of can include, have or be included in described in other embodiment (including system, method, apparatus and/or analog)
Feature, property, component, component, element, step and/or similar fashion.Therefore, the tool relevant with an embodiment is referred to
Body characteristicses are not necessarily to be construed as only limiting the application in this embodiment.
If it will also be appreciated that disclose or describe multiple possibilities of numerical value or number range (for example, being less than, greatly
In, at least or reach between some numerical value or the two values of record), should equally disclose herein and consider to fall into disclosed
The concrete numerical value or number range of number range.
Title used herein is only used for the purpose of layout, is not meant to for limiting specification or claims
Scope.In order to make it easy to understand, if possible, identical reference is used to refer to for the similar elements shared in accompanying drawing.In addition, such as
It is possible to, the reference of identical element uses in multiple accompanying drawings.In addition, the alternative configuration of particular element is each
The individual single word that may include to be attached to element reference.
Fig. 1 shows the base portion 10 of exemplary tube support instrument 8 according to an embodiment of the invention (referring to Fig. 3).Base portion
With support surface 12 and four walls 15,16,17,18, these walls are surrounded by support receiving area 11 and are used to receive pipe holder.
In exemplary embodiment, support surface 12 is along from wall 18 to the axis bending of the direction of wall 17 extension.In certain embodiments,
Support surface 12 can with or alternatively along from wall 16 to the direction of wall 15 extension axis bending.However, as it is following enter one
What step discussed, in certain embodiments, support surface 12 need not have curved configuration.Equally, in the exemplary embodiment, two
Individual distance piece 13,14 is separately positioned between support surface 12 and wall 17,18.Distance piece 13,14 includes opening by base portion 10
Mouthful, although opening 13,14 is optionally provided with bottom to cause recess.Relative recess 20 is also set, respectively on support surface 12
Between wall 15,16.It should be appreciated that wall 15,16,17,18 and distance piece 13,14 and recess 20 be configured to contribute to by
The support of (pipe) is placed and held in support receiving area 11, and any or all these wall, distance piece and/or recesses
All it is optional and is dispensed.Similarly, in certain embodiments, wall need not be all around support receiving area
11。
Fig. 2 is shown can be with the top part 50 that base portion 10 is used together (for example, to form Fig. 3 pipe holder instrument
8).Top part 50 has top 52 and two supporting legs 60,61 extended downwardly from the top 50.Supporting leg 60,61 be spaced apart with
Pipe holder is received therebetween.In alternative embodiments, top part 50 can have the single supporting leg extended downwardly from it or more than two
Supporting leg.For example, single supporting leg can (wholly or partly) extend around top part 50 and/or from the top part 50 to downward
Stretch.Alternatively, three or four supporting legs may be provided at the turning of top part 50.
In described exemplary embodiment, supporting leg 60 is provided with supporting leg extension 63,64, and supporting leg 61 is provided with
Supporting leg extension 65 (and the second supporting leg extension is not shown in fig. 2).Such as the finding of supporting leg extension 63, supporting leg extension is from every
Individual supporting leg is inwardly projecting (for example, towards relative supporting leg).Supporting leg extension can be configured to contribute to accommodate pipe holder and/
Or be appropriately positioned between supporting leg 60,61, and/or limitation pipe holder skids off from the side of top part 50.In greater detail below
Discuss, the support surface 12 that supporting leg extension can also aid in around base portion 10 is properly located pipe holder (Fig. 1).It is optional
Ground, the side wall that extends between supporting leg 60 and 61 is may be provided with instead of or except supporting leg extension, top part 50 to accommodate pipe branch
Frame.
Fig. 3 shows the exploded view of the pipe removing tool component 40 including pipe holder 78, and the pipe holder 78 includes support 80
And 90 six roots of sensation pipes 82 inserted between base portion 10 and top part 50.It should be understood that although exemplary support 80 includes
For the space of 96 pipes, but the support and pipe of any other quantity or setting can be used.In addition, although show
The pipe holder 78 of example property is full, but with it is multiple less than the exemplary embodiment of pipe holder can be used.As above institute
State, being sized to of the wall 15,16,17,18 of base portion 10 can receive pipe holder 78 wherein, so that pipe holder 78 supports
On support surface 12.Because top part 50 is placed on pipe holder 78, the supporting leg 60,61 of top part 50 encloses at least in part
Extended downwardly around pipe 82, fit in the inside of wall 15,16,17,18, and help to maintain support 80 and pipe 82 relative to its base
Portion 10 and/or the orientation of support surface 12.
In the illustrative example, support 80 is provided with 12 rows 85 and often arranges eight pipes 82 it should be appreciated that its
He configures within the scope of the invention.Each pipe 82 has unlimited top 88 and relative, closing bottom 90 (referring to figure
4), bottom 90 is inserted into the respective well 84 in support 80.Well 84 includes the opening in the surface portion 81 of support 80, and
Each pipe 82 or its bottom 90 (referring to Fig. 4) extend in the lower section of the surface portion 81.Can from Fig. 4 viewgraph of cross-section
Go out, the bearing (stand) of support 80 is played a part of in skirt section 89, and extends in the lower section of any bottom 90 of pipe 82.Therefore, when
When support 80 is placed on laboratory table top or other flat surfaces, pipe 82 is spaced apart with the surface, to prevent pipe 82 from branch
Inadvertently discharged in frame 80.
It should be understood that although in figure 3 only have skirt section 89 two walls be it is visible, but support 80 can have gather around
There is the skirt section 89 of two, three or four walls, or can have pin or other bottom tabs pipe 82 is maintained at into rise
State.Pipe 82 can be any construction, exemplarily, have flat, round bottom or conical bottom.Pipe 82 can be caught in support 80, or
Person can be held in place by by pressure.Although Fig. 3-Fig. 5 is not shown, pipe 82 may be provided with cap, exemplarily, Ke Yishi
Nuts, press-fit cap, band cap are attached to or are heat sealed to film on pipe 82.For example, at least one embodiment, such as scheme
Shown in 10- Figure 11, pipe 82 can be with the seal cap 83 for being disposed thereon and/or being attached to thereon (for example, sealing opening portion thereon
88).Within the scope of the invention it is also contemplated that other constructions.
Fig. 4 shows the viewgraph of cross-section of pipe removing tool component 40, and the pipe removing tool component 40 includes：Pipe holder
78, it is inserted into base portion 10；With top part 50, fit on the top of pipe holder 78, and supporting leg 60,61 is in upper surface part 81
Engaged with support 80.Due to the curvature of support surface 12, the only a part of in a row 85 pipe 82 contacts with support surface 12.At this
In exemplary embodiment, the end 86,87 of support 80 is suspended in opening 13,14.Fig. 1 and Fig. 3 show, support surface 12 and wall 15
Between recess 20 allow support 80 skirt section 89 support surface 12 lower section extend.Similar recess (not shown) can be set
Between support surface 12 and wall 16.Therefore, at least one embodiment, the support surface 12 of base portion 10 engages multiple pipes 82
(or bottom of the pipe), but do not engage and/or contact with least a portion in the skirt section 89 of support 80.
The downward pressure of (for example, from top) causes a row or multi-row 85 pipe 82 (or bottom of the pipe 82) on top part 50
Engaged with the support surface 12 of base portion 10, this so that cause that one or more (a row or multi-row 85) pipe 82 starts from the row of support 80
Go out, as shown in Figure 5.Therefore, multiple pipes 82 (for example, an at least row 85) can be simultaneously, in real time and/or synchronously from the branch
Frame 80 is discharged.In one exemplary embodiment, as shown in arrow X-X, before and after surrounding or being carried out along the curvature of support surface 12
Oscillating motion causes extra multiple rows of 85 pipe 82 to be engaged with the support surface 12 of base portion 10, causes extra multiple rows of 85 pipe in turn
82 are discharged from support 80.Opened due to applying pressure in a more direct manner in the top of supporting leg 60, therefore in possible direction
Apply in a more direct manner the top of the cantilevered ends 86 of the deflection of mouth 13 (for example, not engaged with the support surface 12 of base portion 10)
Plus-pressure, so that the row 85 near end 86 discharges.Because top part 50 waves along another direction and in supporting leg 61
On apply pressure in a more direct manner, therefore may deflected towards opening 14 (for example, the not support surface 12 with base portion 10
Engagement) cantilevered end 87 on apply pressure in a more direct manner so that the row 85 near end 87 discharges.Continuously
Move forward and backward and cause all pipes 82 to be unclamped from support 80, most all pipes 82 are discharged from support 80 at last.Therefore, multiple pipes 82
And/or multiple rows of 85 pipe 82 can be simultaneously, in real time, synchronously and/or immediately in order (for example, instantaneously) from the quilt of support 80
Discharge.Then, support 80 and pipe 82 can be removed from base portion 10 and top part 50.
In the exemplary embodiment as shown in Fig. 1 and Fig. 3-Fig. 5, support surface 12 is bending.It is although exemplary
Curvature be with about 20 inch diameters circle circular arc it should be appreciated that what this was merely exemplary, and its
Its curvature is exercisable, exemplarily with 15 inches to 25 inches, 10 inches to 30 inches, or 7 inches to 40 inches
Radius.Although the circle curvature has been used in some embodiments herein it should be appreciated that other shapes are also being invented
In the range of, including it is parabola shaped, and bend in a two-dimensional manner.In an exemplary embodiment, as long as support table
Face 12 is smaller than skirt section 89, and the can of support surface 12 is flat.It should be understood that more flat support surface can be discharged once
More pipe, but larger pressure may be needed, at the same time, more curved support surface can once discharge less pipe,
But less pressure can be needed.In addition, curvature in one direction can be such that pipe is discharged by row, at the same time, along two sides
To curvature can allow the discharge of single pipe or a small group pipe.
It should be understood that in certain embodiments, top part 50 is optional, and support 80 is inserted into base portion 10 can
Allow by Manual pressure directly on the end 86,87 of support 80 or skirt section 89 (for example, along the direction of support surface 12
Pressure on surface 81) remove pipe 82.For example, at least one embodiment, exemplarily pass through one or more of operator
Individual finger or any suitable pressure applying means pressure is applied on surface 81.
Referring back to Fig. 2, in this illustrative embodiment, the top 52 of top part 50 is provided with opening 53.Such as Figure 10-figure
11 are best shown, and top 52 is additionally provided with curved edge 55, it is shaped to be pressed in lid 83 (for example, close with lid 83
Fengkai mouth 88), and be configured to be capped in the pipe 82 of a row 85, such as the arrow in Figure 11 by (downwards) power and/or oscillating motion
Shown in head Y-Y.It should also be noted that curved edge 55 be can be shaped as and/or be configured to by shown in the arrow Y-Y in Figure 11
(pressing) power or oscillating motion (row 85) pipe 82 is arranged in support 80.Alternatively, opening 53 can be provided with grip part 54,
For cosily keeping top part 50 during the Capping operation.
Alternatively, as Figure 12 describes, base portion 10 can be inverted and support surface 12 is positioned at the (row of pipe 82
85) on.The similar oscillating motion shown in the arrow Y-Y in Figure 13 and/or (downwards) power can be applied, in lid 83
Upper pressure (for example, to use the sealed opening 88 of lid 83).It should also be noted that inverted base portion 10 and/or its support surface 12
It is arranged to available for by the part or all of pipe 82 of pipe holder 78 in support 80 (referring to Fig. 3), or by applying on base portion 10
Pressure (for example, using oscillating motion Y-Y) is capped in one or more of pipe holder 78 pipe 82 or a row or multi-row 85 pipe
82 it is part or all of.
Fig. 6-Fig. 7 shows the base portion 110 and top part 150 of the alternate embodiment of pipe removing tool 140, and wherein identical is attached
Icon note represents same parts or the part with identical function.Base portion 110 has support surface 112 and limited for reception pipe
Two walls 115,116 in the space of support.It is different from Fig. 1 base portion 10, in this illustrative embodiment, support surface 112
It is narrow a lot, and be configured to contact single row of tubes 85.It should be understood that support surface 112 may be provided with any shape with appointing
The pipe of what quantity or the pipe contact of any row.For example, support surface 112 can be along from wall 116 to the axle of the direction of wall 115 extension
Line is bent.
Fig. 7 shows top part 150, and it can be used together with base portion 110 to form pipe holder instrument 140, such as Fig. 8 institutes
Show.Top part 150 has top 152 and four supporting legs 158,159,160,161 extended downwardly from top 150.The supporting leg
158th, 159,160,161 it is spaced apart to receive pipe holder 78 therebetween.It should be understood that four supporting legs are only exemplary,
And any or all of supporting leg can be omitted.It is also possible to consider the embodiment with supporting leg extension shown in Fig. 2.It should be understood that
It is that top part 150 is not limited to be used together with base portion 110, according to the needs of concrete application, various top parts as described herein can
To be used together with any compatible base portion.In addition, various top parts as described herein can not also be used together with base portion.Example
Such as, at least one embodiment, pipe holder can be received or be arranged on a part (example of top part by a part for top part
Such as, between supporting leg), and multiple pipes are by pressing (for example, by hand or miscellaneous equipment, device or element) pipe (bottom) from branch
Frame is discharged.
In the exemplary example, two walls 115,116 are only set on base portion 110.Omitting side wall allows support 80
Linearly moved along base portion 110 with top part 150.It is also provided with multiple guiding pieces 128.Make support with one of guiding piece 128
80 or top part 150 be arranged in a row so that a specific comb 85 to be positioned to the top of support surface component 112.Such as Fig. 8-Fig. 9
It is exemplarily illustrated, or even top part 150 is in line the 5th comb 85 from top part 150 with the second guiding piece 128
End be positioned at the top of support surface component 112.As being best shown in Fig. 8, when by top part 150 along support surface
When the direction of component 112 is applied to the pressure on support 80, the comb 85 for being positioned at the top of support surface component 112 is arranged
Go out.As other embodiment, it should be appreciated that top part 150 is optional, and by hand or direct by other devices
Apply pressure to support 80 so that any pipe 82 above the support surface component 112 to be discharged.
It should be appreciated that guiding piece 128 can be provided with mark, with show when top part 150 or support 80 with it is each
Which comb 85 will be removed when guiding piece is aligned.In addition, at least one embodiment, support surface component 112 can be in base portion
Moved in 110.For example, support surface 112 can be arranged in travel mechanism or be connected to travel mechanism, the travel mechanism by with
Being set to allows support surface 112 to be positioned and/or be fixed on multiple opening positions in base portion 110.The travel mechanism may include：
Multiple grooves, it is configured to receive (dismountable) support surface component 112；Track or sliding component, are configured to allow for support surface
Component 112 moves on the track or sliding component, or any other device, for make support surface component 112 movement and/
Or change the position of support surface component 112 and base portion 110.
For those skilled in the relevant art, the various changes of inventive features shown in this article and/or modification and sheet
The additional application of principle shown in text forms example on the premise of without departing substantially from spirit and scope of the invention
The embodiment of property and it can be deemed within the scope of the present invention.Therefore, although having been disclosed for various schemes and implementation herein
Example, but other schemes and embodiment should also be considered.Although can use with it is described herein similar or equivalent multiple
Method and component realize embodiments of the invention, but only describe some components and method herein.
Also it will be appreciated that system, technique and/or product according to certain embodiments of the present invention can wrap
Include, be incorporated to or the attributive character described in the present invention other embodiment that discloses and/or describe is (for example, component, structure
Part, element, part and/or part).Therefore, each feature of some embodiments can it is compatible, combine, include and/or be incorporated into
In other embodiments of the invention.Therefore, some features of the open specific embodiment relative to the present invention are not necessarily to be construed as
Application to the feature of specific embodiment and the limitation included.Conversely, it should be appreciated that need not necessarily depart from the present invention's
Other embodiments can also include the feature on the premise of scope.In addition, unless describe feature as needing in combination
Another feature, otherwise any feature can be with any other combinations of features in identical or different embodiment disclosed herein.
In addition, each known technical scheme progress herein not to example system, technique, product and the like is especially detailed
Carefully describe, to avoid making the scheme of exemplary embodiment smudgy.However, these technical schemes should also be examined herein
Consider.
In the case where not departing from the spirit or essential attributes of the present invention, the present invention can be implemented in other specific forms.
Described embodiment is considered in all respects only as illustrative rather than restrictive.Therefore, the scope of the present invention is by institute
Attached claim rather than preceding description represent.Although will be in invention and appended in order to describe the purpose of embodiments of the invention
Include some embodiments and details in disclosure, it will be apparent to those skilled in the art that not departing from by appended
On the premise of the scope of the present invention that claim limits, it can allow to carry out various changes to method disclosed herein and device
Change.All changes in the implication of claim and the scope of equivalent are intended to be included in the range of it.
Claims (36)
1. a kind of pipe holder instrument, including：
Base portion, has the receiving area for being sized for receiving pipe holder, and the pipe holder includes the microtitration with multiple wells
Plate and the multiple pipes being arranged in the well；The base portion, which has, to be used to engage the institute being arranged in the well of the microtiter plate
State the surface of multiple pipes so that pressure is applied with from the microtiter plate to the microtiter plate along the direction on the surface
Discharge the multiple pipe.
2. pipe holder instrument as claimed in claim 1, wherein the microtiter plate includes at least 96 wells.
3. pipe holder instrument as claimed in claim 1, wherein the multiple well is arranged to multiple rows of, the surface is sized for
Engagement is arranged on all pipes in an at least row.
4. pipe holder instrument as claimed in claim 1, wherein the surface is bending so that applied to the microtiter plate
During plus-pressure, the oscillating motion of the microtiter plate substantially discharges all pipes from the microtiter plate.
5. pipe holder instrument as claimed in claim 1, in addition to top part, the top member configurations are into the microtitration
The pipe holder is kept to be engaged with the surface while applying pressure on plate.
6. pipe holder instrument as claimed in claim 5, wherein the microtiter plate includes upper surface part and around described more
The skirt section that individual well is set, the multiple well are included in the opening in the upper surface part, and the skirt section is prolonged from the upper surface part
Stretch, the top part is configured to apply pressure in the upper surface part.
7. pipe holder instrument as claimed in claim 6, wherein the top part includes one or more branch from top extension
Leg, one or more of supporting legs are configured to receive the multiple pipe and engage the upper surface part of the microtiter plate.
8. pipe holder instrument as claimed in claim 6, wherein the surface of the base portion is less than the skirt section, and it is configured to
Receive pipe holder in the case of not engaging the skirt section, the top member configurations into the upper surface part ratio in the multiple pipe
It is upper to apply bigger downward pressure.
9. pipe holder instrument as claimed in claim 1, wherein when the pipe holder is received by the base portion, the base portion
Basal surface of the surface structure into the multiple pipe of engagement.
10. a kind of pipe holder instrument, including for receiving the base portion of pipe holder, the base portion has the table for being used for engaging the pipe
Face, wherein the pressure on the support makes multiple pipes be discharged from the support.
11. pipe holder instrument as claimed in claim 10, wherein the surface is bending.
12. pipe holder instrument as claimed in claim 11, wherein the shaping surface is so that applies pressure to the support
When, the oscillating motion of the support substantially discharges whole pipes from the support.
13. pipe holder instrument as claimed in claim 10, wherein the shaping surface is one comb of removal.
14. pipe holder instrument as claimed in claim 10, wherein the base portion is provided with multiple guiding pieces to help to position institute
Pipe holder is stated to remove a specific comb.
15. pipe holder instrument as claimed in claim 10, in addition to top part, the top member configurations are on the bracket
The pipe holder is kept to be engaged with the surface while applying pressure.
16. pipe holder instrument as claimed in claim 10, wherein the pipe holder instrument is sized for receiving 96 well type micro-
Titer plate is measured, the pipe holder includes the support and 96 pipes.
17. a kind of pipe holder instrument, including：
Base portion, for receiving pipe holder, the pipe holder includes setting multiple pipes in the bracket, and the base portion, which has, to be used to connect
Close the surface for the multiple pipes being arranged in the support；And
Top part, for engaging the support, wherein the pressure on the top part discharges the multiple pipe from the support.
18. pipe holder instrument as claimed in claim 17, wherein the support includes upper surface part and around the multiple pipe
Skirt section, the top member configurations is apply pressure on the skirt section or the upper surface part.
19. pipe holder instrument as claimed in claim 18, wherein the surface of the base portion is less than the skirt section, and it is configured to
The pipe holder is received in the case where not engaging the skirt section.
20. pipe holder instrument as claimed in claim 17, wherein the surface of the base portion is configured to engage the multiple pipe
In each basal surface.
21. pipe holder instrument as claimed in claim 17, in addition to curved edge, the curved edge is configured to apply covering
Plus-pressure is to seal the multiple pipe of a row.
22. pipe holder instrument as claimed in claim 21, wherein the curved edge is arranged on the top part.
23. a kind of method that multiple pipes are removed from the pipe holder with support and sleeve, including：
Pipe holder is put into base portion, the base portion has the surface for being used for engaging multiple pipes in the pipe holder, and
Apply pressure on the bracket so that the multiple pipe to be discharged from the support.
24. method as claimed in claim 23, in addition to：
Top part is placed on to the top of the pipe holder, wherein the step of applying pressure includes：Apply to the top part and press
Power to apply pressure on the bracket, so as to which the multiple pipe be discharged.
25. method as claimed in claim 23, wherein the surface is bending, and include waving the step of apply pressure
The top part, so as to substantially all discharge the sleeve pipe.
26. method as claimed in claim 23, wherein the multiple pipe is a comb, the shaping surface is the removal row
The step of managing, and applying pressure discharges the comb.
27. method as claimed in claim 23, wherein applying the pressure on the bracket along the direction on the surface.
28. a kind of pipe removal system, including：
Pipe holder, including microtiter plate, the microtiter plate have multiple wells and the multiple pipes being arranged in the well, institute
Stating microtiter plate has the upper surface part set around the multiple well, and the multiple well is included in the upper surface part
Opening；And
Pipe holder instrument, it is configured to receive the pipe holder, the pipe holder instrument includes：
Base portion, there is the receiving area for being sized for receiving the pipe holder, the base portion has a surface, when the pipe holder
When being arranged on the receiving area, the surface engagement is arranged on the multiple pipe in the well of the microtiter plate；With
And
Top part, it is configured to keep the pipe holder to connect with the surface while pressure is applied on the microtiter plate
Close, the top part has one or more supporting legs, and one or more of supporting legs are configured to engage the microtiter plate
Upper surface part so that be applied to the pressure of the top part by the multiple pipe from the microtitration along the direction on the surface
Discharged on plate.
29. pipe removal system as claimed in claim 28, wherein the microtiter plate includes at least 96 wells.
30. pipe removal system as claimed in claim 28, wherein the multiple well is arranged to multiple rows of, the surface of the base portion is big
The small all pipes being adapted to engage with being arranged in an at least row.
31. pipe removal system as claimed in claim 28, wherein the surface is bending so as to the microtiter plate
When applying pressure, the oscillating motion of the microtiter plate substantially discharges all pipes from the microtiter plate.
32. pipe removal system as claimed in claim 28, wherein the microtiter plate also includes setting around the multiple well
The skirt section put, the skirt section extend from the upper surface part.
33. pipe removal system as claimed in claim 32, wherein the surface of the base portion is less than the skirt section, and it is constructed
Into receiving the pipe holder in the case where not engaging the skirt section, the top member configurations into the upper surface part ratio in institute
State and apply bigger downward pressure on multiple pipes.
34. pipe removal system as claimed in claim 28, wherein the surface structure of the base portion is into when the pipe holder is by institute
State the basal surface that the multiple pipe is engaged when base portion is received.
35. pipe removal system as claimed in claim 28, wherein the base portion is provided with multiple pipes, to help to position the pipe
Support removes a specific comb.
36. pipe removal system as claimed in claim 28, wherein the pipe holder instrument is sized for receiving 96 well type micro-
Titer plate is measured, the pipe holder includes the support and 96 pipes.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201514998015A | 2015-02-24 | 2015-02-24 | |
| US14/998,015 | 2015-02-24 | ||
| PCT/US2016/017620 WO2016137756A1 (en) | 2015-02-24 | 2016-02-11 | Tube rack tool |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107405622A true CN107405622A (en) | 2017-11-28 |
| CN107405622B CN107405622B (en) | 2019-05-28 |
Family
ID=59191991
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201680011997.8A Active CN107405622B (en) | 2015-02-24 | 2016-02-11 | Pipe holder tool |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | USD791337S1 (en) |
| EP (1) | EP3261764A4 (en) |
| CN (1) | CN107405622B (en) |
| BR (1) | BR112017018124B1 (en) |
| CA (1) | CA2977505C (en) |
| CL (1) | CL2017002151A1 (en) |
| NZ (1) | NZ734396A (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USD825775S1 (en) * | 2016-10-17 | 2018-08-14 | Becton, Dickinson And Company | Tube tray |
| USD826426S1 (en) * | 2016-10-17 | 2018-08-21 | Becton, Dickinson And Company | Tube tray |
| USD826425S1 (en) * | 2016-10-17 | 2018-08-21 | Becton, Dickinson And Company | Tube tray |
| USD852978S1 (en) * | 2017-06-26 | 2019-07-02 | Seville Medical Inc. | Surgical tool organizer |
| USD908224S1 (en) * | 2018-06-11 | 2021-01-19 | Siemens Healthcare Gmbh | Component for patient table |
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| US6533133B2 (en) * | 2001-05-18 | 2003-03-18 | Jun-Tai Liu | Test tube rack with inserting structure |
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| CN204074121U (en) * | 2014-07-30 | 2015-01-07 | 台州市黄岩方野科技发展有限公司 | Test tube case |
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| USD466219S1 (en) * | 1999-09-13 | 2002-11-26 | Micronic B.V. | Carrier for test-tubes |
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- 2016-02-11 EP EP16756063.0A patent/EP3261764A4/en active Pending
- 2016-02-11 CN CN201680011997.8A patent/CN107405622B/en active Active
- 2016-02-11 NZ NZ734396A patent/NZ734396A/en unknown
- 2016-02-11 BR BR112017018124-0A patent/BR112017018124B1/en active IP Right Grant
- 2016-02-24 US US29/555,675 patent/USD791337S1/en active Active
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|---|---|---|---|---|
| US6533133B2 (en) * | 2001-05-18 | 2003-03-18 | Jun-Tai Liu | Test tube rack with inserting structure |
| CN2875581Y (en) * | 2006-01-17 | 2007-03-07 | 李继广 | Test tube stand |
| CN201091840Y (en) * | 2007-08-23 | 2008-07-30 | 天津市口腔医院 | Lift type test-tube rack |
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Also Published As
| Publication number | Publication date |
|---|---|
| USD791337S1 (en) | 2017-07-04 |
| BR112017018124A2 (en) | 2018-04-10 |
| EP3261764A4 (en) | 2018-07-18 |
| CN107405622B (en) | 2019-05-28 |
| EP3261764A1 (en) | 2018-01-03 |
| BR112017018124B1 (en) | 2022-09-13 |
| NZ734396A (en) | 2019-03-29 |
| CL2017002151A1 (en) | 2018-03-16 |
| CA2977505A1 (en) | 2016-09-01 |
| CA2977505C (en) | 2018-06-12 |
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