CN107397603A - nude mice local irradiation fixing device - Google Patents
nude mice local irradiation fixing device Download PDFInfo
- Publication number
- CN107397603A CN107397603A CN201710623808.9A CN201710623808A CN107397603A CN 107397603 A CN107397603 A CN 107397603A CN 201710623808 A CN201710623808 A CN 201710623808A CN 107397603 A CN107397603 A CN 107397603A
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- CN
- China
- Prior art keywords
- sliding block
- slide rail
- nude mice
- slider
- bolt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
- A61D2003/006—Appliances for supporting or fettering animals for operative purposes with leg or foot restraining means
Abstract
The invention discloses nude mice local irradiation fixing device, including base, first slide rail, first sliding block, barricade, second slide rail, second sliding block, 3rd sliding block, 3rd slide rail, Four-slider, fixed plate, standing groove, cushion, screw rod, pressing plate, the nude mice local irradiation fixing device, clever structure, it is powerful, by using the device, experiment nude mice four limbs can not only effectively be fixed, so as to avoid nude mice from situation about escaping occur, improve the convenient of experimental implementation, further according to needs, it can realize that the radiation proof to nude mice body part is blocked by shirtsleeve operation, so as to greatly improve the validity of experimental study.
Description
Technical field
The present invention relates to zoopery field, more particularly to nude mice local irradiation fixing device.
Background technology
Nude mice is because Immunodeficiency need to be raised in SPF levels environment, while transplanted tumor in nude mice is to study tumor invasion in body
The important method of mechanism, transfer and relapse and treatment method., often need to be by nude mice from specific feeding environment for tumour radiotherapy biology
Under be transferred to Radiation Center or other irradiation facilities in, nude mice research or transfer process in, for avoid occur nude mice escape feelings
Condition, so as to need that its four limbs is fixed, fixed form traditional at present is generally simple, more using tied rope etc. to nude mice four limbs
Rope system, but aforesaid way are carried out, not only operation is wasted time and energy, and can not also effectively be reached the effect fixed to nude mice, is easily caused naked
There is the situation of shaking off in mouse, in addition, when carrying out radiation research to nude mice part limbs, it is necessary to which remaining limbs carries out anti-spoke to nude mice
Penetrate and block, in view of disadvantages described above, is necessary to design nude mice local irradiation fixing device in fact.
The content of the invention
The technical problems to be solved by the invention are：There is provided nude mice local irradiation fixing device, come solve currently for
Such as nude mice one kind experimental animal research process, effectively its four limbs can not be fixed very well, and can not be to local limb
Body carries out the problem of radiation proof is blocked.
In order to solve the above technical problems, the technical scheme is that：Nude mice local irradiation fixing device, including base,
First slide rail, the first sliding block, barricade, the second slide rail, the second sliding block, the 3rd sliding block, the 3rd slide rail, Four-slider, fixed plate,
Standing groove, cushion, screw rod, pressing plate, the first described slide rail are located at base rear and front end, the first described slide rail and whorl of base
Be connected, described the first sliding block quantity is four, and the first described sliding block be located at the first slide rail outer wall, the first described sliding block and
First slide rail, which slides, to be connected, and described barricade quantity is two pieces, and described barricade is located at the first slider top, described screen
Shield plate is integrally connected with the first sliding block, and the second described slide rail is located at base top rear and front end, the second described slide rail and bottom
Seat screw thread is connected, and the second described sliding block quantity is two pieces, and the second described sliding block is located at outer wall on the left of the second slide rail, described
Second sliding block slides with the second slide rail to be connected, and the 3rd described sliding block quantity is two pieces, and the 3rd described sliding block is slided positioned at second
Rail outer right wall, the 3rd described sliding block and the second slide rail, which slide, to be connected, the 3rd described slide rail be located at the 3rd sliding block two-by-two it
Between, the 3rd described slide rail and the 3rd sliding block are integrally connected, and described Four-slider quantity is two pieces, described Four-slider position
In the 3rd slide rail outer wall rear and front end, described Four-slider slides with the 3rd slide rail to be connected, and described fixed plate quantity is four
Part, described fixed plate respectively at the top of the second sliding block and Four-slider, described fixed plate respectively with the second sliding block and the
Four-slider is integrally connected, and described standing groove is located at fixed plate interior lower end, and described standing groove is groove, described cushion position
In standing groove inwall, described cushion is connected with fixed plate glue, and described screw rod runs through fixed plate inner upper end, described spiral shell
Bar is connected with fixed plate screw thread, and described pressing plate is located at screw rod bottom, and described pressing plate is integrally connected with screw rod.
Further, the first limiting plate, the first described limiting plate and first are additionally provided with left and right sides of the first described slide rail
Slide rail screw thread is connected.
Further, middle-end has also extended through the first bolt inside the first described sliding block, and the first described bolt and first are slided
Block screw thread is connected.
Further, the second limiting plate, the second described limiting plate and second are additionally provided with left and right sides of the second described slide rail
Slide rail screw thread is connected.
Further, the second described sliding block inside left top is additionally provided with the second bolt, the second described bolt and second
Sliding block screw thread is connected.
Further, the 3rd described sliding block inside left top is additionally provided with the 3rd bolt, the 3rd described bolt and the 3rd
Sliding block screw thread is connected.
Further, described Four-slider inner tip is additionally provided with the 4th bolt, the 4th described bolt and Four-slider
Screw thread is connected.
Further, described chassis interior is additionally provided with receiver, and described receiver is movably connected with base.
Compared with prior art, nude mice local irradiation fixing device, in use, experimenter is first according to nude mice build
Size, by unclamping the second bolt, the second sliding block is active, then pulls the second sliding block, make the second sliding block along
Two slide rails make the motion of left and right directions, behind position needed for the arrival of the second sliding block, can tighten the second bolt, that is, realize the second cunning
The 3rd bolt is unclamped in the fixation of block, similarly, experimenter, is active the 3rd sliding block, then pull the 3rd sliding block, makes the
Three sliding blocks make the motion of left and right directions along the second slide rail, behind position needed for the arrival of the 3rd sliding block, can tighten the 3rd bolt, i.e.,
The fixation of the 3rd sliding block is realized, similarly, experimenter unclamps the 4th bolt, is active Four-slider, then pull
Four-slider, Four-slider is made the motion of fore-and-aft direction along the 3rd slide rail, behind position needed for Four-slider arrival, can twist
Tight 4th bolt, that is, realize the fixation of Four-slider, eventually through above-mentioned operation, makes the fixed plate interval of diverse location big
It is small with experiment nude mice four limbs apart from equal, then, nude mice can be firstly placed on base by experimenter, then nude mice four limbs are inserted into
In standing groove in fixed plate, i.e. nude mice four limbs are bonded with cushion, then, the rotatable screw rod of experimenter, screw rod is promoted pressure
Plate moves from top to bottom along fixed plate, and when pressing plate touches nude mice four limbs, the effect that is clamped by pressing plate realizes pair
The fixation of nude mice four limbs, that is, have the function that to prevent nude mice from escaping, then, experimenter can carry out nude mice related real
Research is tested, in addition, when experimenter needs to carry out radiation research to nude mice part limbs, can first unclamp the first bolt,
The first sliding block is active, further according to pulling barricade is needed, barricade is driven the first sliding block along the first slide rail
Make the motion of left and right directions, after barricade, which shelters from nude mice, to irradiate position, barricade can be stopped drag, then tighten first
Bolt, that is, the fixation of barricade is realized, then, experimenter can irradiate to nude mice exposure portion, because of shielding
Sheet material matter is stereotype, can be good at playing radiation protection, so as to improve the validity of experimental study, the nude mice part spoke
According to fixing device, clever structure is powerful, by using the device, experiment nude mice four limbs can not only be carried out effective
It is fixed, so as to avoid nude mice from situation about escaping occur, the convenient of experimental implementation is improved, further according to needs, by simple
Operation can realize that the radiation proof to nude mice body part is blocked, so as to greatly improve the validity of experimental study, first
Limiting plate is spacing in order to slide progress to the first sliding block, and the second limiting plate is in order to the second sliding block and the slip of the 3rd sliding block
Carry out spacing, receiver is to store the contaminated liquid dripped in the pollutant of experimental mouse excretion and experiment.
Brief description of the drawings
Fig. 1 is the front view of nude mice local irradiation fixing device；
Fig. 2 is the top view of nude mice local irradiation fixing device；
Fig. 3 is the A of nude mice local irradiation fixing device to sectional view；
Fig. 4 is the first sliding block cutaway view Amplified image；
Fig. 5 is fixed plate position enlarged drawing.
Base 1, the first slide rail 2, the first sliding block 3, barricade 4, the second slide rail 5, the second sliding block 6, the 3rd sliding block the 7, the 3rd
Slide rail 8, Four-slider 9, fixed plate 10, standing groove 11, cushion 12, screw rod 13, pressing plate 14, receiver 101, the first limiting plate
201st, the first bolt 301, the second limiting plate 501, the second bolt 601, the 3rd bolt 701, the 4th bolt 901.
Following embodiment will combine above-mentioned accompanying drawing and further illustrate.
Embodiment
Hereinafter, a variety of specific details are elaborated, to provide the saturating of the concept to forming described embodiment basis
Thorough understanding, however, it will be apparent to those skilled in the art that described embodiment can be in these no specific details
In it is some or all in the case of put into practice, in other cases, do not specifically describe well-known processing step.
As shown in Figure 1, Figure 2, shown in Fig. 3, Fig. 4, Fig. 5, nude mice local irradiation fixing device, including base 1, the first slide rail 2,
One sliding block 3, barricade 4, the second slide rail 5, the second sliding block 6, the 3rd sliding block 7, the 3rd slide rail 8, Four-slider 9, fixed plate 10, put
Groove 11, cushion 12, screw rod 13, pressing plate 14 are put, the first described slide rail 2 is located at the rear and front end of base 1, the first described slide rail 2
It is connected with the screw thread of base 1, the described quantity of the first sliding block 3 is four, and the first described sliding block 3 is located at the outer wall of the first slide rail 2, institute
The first sliding block 3 stated and the first slide rail 2, which slide, to be connected, and the described quantity of barricade 4 is two pieces, and described barricade 4 is located at the
The top of one sliding block 3, described barricade 4 are connected with the one of the first sliding block 3, and the second described slide rail 5 is located at before and after the top of base 1
Both ends, the second described slide rail 5 are connected with the screw thread of base 1, and the described quantity of the second sliding block 6 is two pieces, the second described sliding block 6
Positioned at the left side outer wall of the second slide rail 5, the second described sliding block 6 slides with the second slide rail 5 to be connected, the described quantity of the 3rd sliding block 7
For two pieces, the 3rd described sliding block 7 is located at the outer right wall of the second slide rail 5, and the 3rd described sliding block 7 slides phase with the second slide rail 5
Even, the 3rd described slide rail 8 is located at the 3rd sliding block 7 between any two, and the 3rd described slide rail 8 is connected with the one of the 3rd sliding block 7, institute
The quantity of Four-slider 9 stated is two pieces, and described Four-slider 9 is located at the outer wall rear and front end of the 3rd slide rail 8, and the described the 4th slides
Block 9 slides with the 3rd slide rail 8 to be connected, and the described quantity of fixed plate 10 is four, and described fixed plate 10 is slided positioned at second respectively
Block 6 and the top of Four-slider 9, described fixed plate 10 are connected with the second sliding block 6 and the one of Four-slider 9 respectively, and described puts
To put groove 11 and be located at the interior lower end of fixed plate 10, described standing groove 11 is groove, and described cushion 12 is located at the inwall of standing groove 11,
Described cushion 12 is connected with the glue of fixed plate 10, and described screw rod 13 runs through the inner upper end of fixed plate 10, described screw rod 13
It is connected with the screw thread of fixed plate 10, described pressing plate 14 is located at the bottom of screw rod 13, and described pressing plate 14 is connected with the one of screw rod 13, institute
The left and right sides of the first slide rail 2 stated is additionally provided with the first limiting plate 201, the first described limiting plate 201 and the screw thread phase of the first slide rail 2
Even, the described inside middle-end of the first sliding block 3 has also extended through the first bolt 301, described the first bolt 301 and the spiral shell of the first sliding block 3
Line is connected, and the described left and right sides of the second slide rail 5 is additionally provided with the second limiting plate 501, and the second described limiting plate 501 and second is slided
The screw thread of rail 5 is connected, and the described inside left top of the second sliding block 6 is additionally provided with the second bolt 601, the second described bolt 601 with
The screw thread of second sliding block 6 is connected, and the described inside left top of the 3rd sliding block 7 is additionally provided with the 3rd bolt 701, the 3rd described bolt
701 are connected with the screw thread of the 3rd sliding block 7, and the described inner tip of Four-slider 9 is additionally provided with the 4th bolt 901, the 4th described spiral shell
Bolt 901 is connected with the screw thread of Four-slider 9, and receiver 101, described receiver 101 and base are additionally provided with inside described base 1
1 is movably connected.
The nude mice local irradiation fixing device, in use, experimenter is first according to nude mice body size, by unclamping the
Two bolts 601, the second sliding block 6 is active, then pulls the second sliding block 6, the second sliding block 6 is made along the second slide rail 5
The motion of left and right directions, after the second sliding block 6 reaches required position, the second bolt 601 can be tightened, that is, realizes the second sliding block 6
Fixation, similarly, experimenter unclamps the 3rd bolt 701, is active the 3rd sliding block 7, then pull the 3rd sliding block 7,
The 3rd sliding block 7 is made the motion of left and right directions along the second slide rail 5, after the 3rd sliding block 7 reaches required position, the 3rd can be tightened
Bolt 701, that is, the fixation of the 3rd sliding block 7 is realized, similarly, experimenter unclamps the 4th bolt 901, is in Four-slider 9
Active state, then Four-slider 9 is pulled, Four-slider 9 is made the motion of fore-and-aft direction along the 3rd slide rail 8, when Four-slider 9
Behind position needed for arrival, the 4th bolt 901 can be tightened, that is, realizes the fixation of Four-slider 9, eventually through above-mentioned operation,
Making the gap size of fixed plate 10 of diverse location and experiment nude mice four limbs, then, experimenter can first put nude mice apart from equal
It is inserted on base 1, then by nude mice four limbs in the standing groove 11 in fixed plate 10, i.e., nude mice four limbs are bonded with cushion 12, are connect
, the rotatable screw rod 13 of experimenter, make screw rod 13 promote pressing plate 14 to be moved from top to bottom along fixed plate 10, when pressing plate 14
When touching nude mice four limbs, the effect that is clamped by pressing plate 14 realizes the fixation to nude mice four limbs, that is, reaching prevents nude mice from going out
The effect now escaped, then, experimenter can carry out Related Experimental Study to nude mice, in addition, when experimenter needs
When carrying out radiation research to nude mice part limbs, the first bolt 301 can be first unclamped, is active the first sliding block 3, then root
According to pulling barricade 4 is needed, make barricade 4 drive the first sliding block 3 to make the motion of left and right directions along the first slide rail 2, work as shielding
Plate 4 is sheltered from after nude mice need not irradiate position, can stop drag barricade 4, then tightens the first bolt 301, that is, realizes shielding
The fixation of plate 4, then, experimenter can irradiate to nude mice exposure portion, because the material of barricade 4 is stereotype, energy
It is enough to play radiation protection well, so as to improve the validity of experimental study, meanwhile, the first limiting plate 201 is in order to right
The slip progress of first sliding block 3 is spacing, and the second limiting plate 501 is limited to be slided to the second sliding block 6 and the 3rd sliding block 7
Position, receiver 101 are to store the contaminated liquid dripped in the pollutant of experimental mouse excretion and experiment.
The present invention is not limited to above-mentioned specific embodiment, one of ordinary skill in the art from above-mentioned design,
Without performing creative labour, a variety of conversion made, it is within the scope of the present invention.
Claims (8)
1. nude mice local irradiation fixing device, it is characterised in that slided including base, the first slide rail, the first sliding block, barricade, second
Rail, the second sliding block, the 3rd sliding block, the 3rd slide rail, Four-slider, fixed plate, standing groove, cushion, screw rod, pressing plate, described
One slide rail is located at base rear and front end, and the first described slide rail is connected with whorl of base, and the first described sliding block quantity is four,
The first described sliding block is located at the first slide rail outer wall, and the first described sliding block slides with the first slide rail to be connected, described barricade
Quantity is two pieces, and described barricade is located at the first slider top, and described barricade is integrally connected with the first sliding block, described
Second slide rail is located at base top rear and front end, and the second described slide rail is connected with whorl of base, the second described sliding block quantity
For two pieces, the second described sliding block is located at outer wall on the left of the second slide rail, and the second described sliding block slides with the second slide rail to be connected, institute
The 3rd sliding block quantity stated is two pieces, and the 3rd described sliding block is located at the second slide rail outer right wall, the 3rd described sliding block and
Two slide rails, which slide, to be connected, and the 3rd described slide rail is located at the 3rd sliding block between any two, the 3rd described slide rail and the 3rd sliding block one
Body phase connects, and described Four-slider quantity is two pieces, and described Four-slider is located at the 3rd slide rail outer wall rear and front end, described
Four-slider slides with the 3rd slide rail to be connected, and described fixed plate quantity is four, and described fixed plate is slided positioned at second respectively
At the top of block and Four-slider, described fixed plate is integrally connected with the second sliding block and Four-slider respectively, described standing groove position
In fixed plate interior lower end, described standing groove is groove, and described cushion is located at standing groove inwall, described cushion and fixation
Plate glue is connected, and described screw rod runs through fixed plate inner upper end, and described screw rod is connected with fixed plate screw thread, described pressing plate
Positioned at screw rod bottom, described pressing plate is integrally connected with screw rod.
2. nude mice local irradiation fixing device as claimed in claim 1, it is characterised in that at left and right sides of the first described slide rail
The first limiting plate is additionally provided with, the first described limiting plate is connected with the first slide rail screw thread.
3. nude mice local irradiation fixing device as claimed in claim 2, it is characterised in that middle-end inside the first described sliding block
The first bolt is also extended through, the first described bolt is connected with the first sliding block screw thread.
4. nude mice local irradiation fixing device as claimed in claim 3, it is characterised in that at left and right sides of the second described slide rail
The second limiting plate is additionally provided with, the second described limiting plate is connected with the second slide rail screw thread.
5. nude mice local irradiation fixing device as claimed in claim 4, it is characterised in that the second described sliding block inside left
Top is additionally provided with the second bolt, and the second described bolt is connected with the second sliding block screw thread.
6. nude mice local irradiation fixing device as claimed in claim 5, it is characterised in that the 3rd described sliding block inside left
Top is additionally provided with the 3rd bolt, and the 3rd described bolt is connected with the 3rd sliding block screw thread.
7. nude mice local irradiation fixing device as claimed in claim 6, it is characterised in that described Four-slider inner tip
The 4th bolt is additionally provided with, the 4th described bolt is connected with Four-slider screw thread.
8. nude mice local irradiation fixing device as claimed in claim 7, it is characterised in that described chassis interior is additionally provided with receipts
Case, described receiver are movably connected with base.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720150206 | 2017-02-20 | ||
| CN2017201502061 | 2017-02-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107397603A true CN107397603A (en) | 2017-11-28 |
Family
ID=60401556
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710623808.9A Pending CN107397603A (en) | 2017-02-20 | 2017-07-27 | nude mice local irradiation fixing device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107397603A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109009543A (en) * | 2018-06-20 | 2018-12-18 | 阮晓青 | Shelf for keeing is used in a kind for the treatment of of livestock-raising ox |
| CN109381298A (en) * | 2018-12-07 | 2019-02-26 | 江苏省人民医院（南京医科大学第附属医院） | Multifunctional medical puncture patient transfer flat car |
| CN110161179A (en) * | 2018-03-27 | 2019-08-23 | 广东华斓汽车材料研究院 | A kind of abrasion resistant materials Element detection instrument |
| CN111631835A (en) * | 2020-06-10 | 2020-09-08 | 甘肃农业大学 | Fixing device is dissected to experimental animals |
| CN115607860A (en) * | 2022-12-15 | 2023-01-17 | 首都医科大学宣武医院 | Device and method for establishing carotid artery stenosis mouse model after radiotherapy |
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| CN203915128U (en) * | 2014-04-22 | 2014-11-05 | 刘树雷 | Tail vein blood device for mouse |
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| CN204501090U (en) * | 2015-03-28 | 2015-07-29 | 黑龙江职业学院 | Extremity location bed is used in a kind of animal and veterinary operation |
| CN205758758U (en) * | 2016-05-24 | 2016-12-07 | 中国人民解放军第四军医大学 | A kind of packaged type nude mice radiotherapy shielding protector |
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| CN202078421U (en) * | 2011-05-12 | 2011-12-21 | 施文祥 | Multifunctional mice and rats experiment table |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110161179A (en) * | 2018-03-27 | 2019-08-23 | 广东华斓汽车材料研究院 | A kind of abrasion resistant materials Element detection instrument |
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| CN109381298A (en) * | 2018-12-07 | 2019-02-26 | 江苏省人民医院（南京医科大学第附属医院） | Multifunctional medical puncture patient transfer flat car |
| CN109381298B (en) * | 2018-12-07 | 2023-09-08 | 江苏省人民医院（南京医科大学第一附属医院） | Multifunctional medical puncture patient transferring flatcar |
| CN111631835A (en) * | 2020-06-10 | 2020-09-08 | 甘肃农业大学 | Fixing device is dissected to experimental animals |
| CN115607860A (en) * | 2022-12-15 | 2023-01-17 | 首都医科大学宣武医院 | Device and method for establishing carotid artery stenosis mouse model after radiotherapy |
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Application publication date: 20171128 |