CN107375711B - Bletilla striata buccal tablet - Google Patents

Bletilla striata buccal tablet Download PDF

Info

Publication number
CN107375711B
CN107375711B CN201710741453.3A CN201710741453A CN107375711B CN 107375711 B CN107375711 B CN 107375711B CN 201710741453 A CN201710741453 A CN 201710741453A CN 107375711 B CN107375711 B CN 107375711B
Authority
CN
China
Prior art keywords
powder
swallow
bletilla striata
layer
knot
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201710741453.3A
Other languages
Chinese (zh)
Other versions
CN107375711A (en
Inventor
刘文明
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guizhou Shengmao Bletilla Striata Development Co ltd
Original Assignee
Guizhou Shengmao Bletilla Striata Development Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guizhou Shengmao Bletilla Striata Development Co ltd filed Critical Guizhou Shengmao Bletilla Striata Development Co ltd
Priority to CN201710741453.3A priority Critical patent/CN107375711B/en
Publication of CN107375711A publication Critical patent/CN107375711A/en
Application granted granted Critical
Publication of CN107375711B publication Critical patent/CN107375711B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288—Taraxacum (dandelion)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/758—Zanthoxylum, e.g. pricklyash
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/898—Orchidaceae (Orchid family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2063—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2068—Compounds of unknown constitution, e.g. material from plants or animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/288—Compounds of unknown constitution, e.g. material from plants or animals

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a bletilla striata buccal tablet in the field of health products, which comprises a membrane coat, an instant layer, a slow dissolving layer, a core body and an anti-swallow mechanism, wherein the anti-swallow mechanism comprises a positioning card, a pull wire and an anti-swallow knot, one end of the pull wire is fixed in the middle of the inner side of an arc surface of the positioning card, the other end of the pull wire is fixed on the anti-swallow knot, the membrane coat, the instant layer, the slow dissolving layer and the core body are sequentially coated on the anti-swallow knot from outside to inside, and the anti-swallow knot comprises two equal-diameter rings which; the membrane coat is prepared by mixing bletilla hyacinthine gum and glutinous rice slurry, the instant layer is prepared by mixing bletilla hyacinthine powder, rhizoma corydalis powder, radix Glycyrrhizae powder, sodium bicarbonate and tartaric acid, the slow-dissolving layer is prepared by mixing bletilla hyacinthine powder, fructus Zanthoxyli powder, herba Taraxaci powder, bletilla hyacinthine gum, edible gelatin and agar, and the core body is prepared by mixing bletilla hyacinthine powder, Mel and Corii Sus Domestica jelly. The scheme solves the problem that the existing buccal tablet is easy to swallow by mistake in the using process, and can effectively prevent the buccal tablet from being swallowed by mistake and causing the potential safety hazard of suffocation in the esophagus or trachea.

Description

Bletilla striata buccal tablet
Technical Field
The invention relates to the field of health products, and in particular relates to a bletilla striata buccal tablet.
Background
With the improvement of living standard of people, people are more and more diversified in life style selection, and more people are caused to have sub-health states, wherein oral problems such as gum bleeding, swelling and pain, oral ulcer and the like are the most obvious and the most common sub-health diseases.
At present, a plurality of methods for treating the oral diseases are available, firstly, vitamin C is taken, only basic antibacterial and anti-inflammatory effects are achieved, and the effect is not ideal; secondly, the oral hygiene products and the tooth care products are used, the surface is clean, the effect is achieved to a certain extent, but the symptoms are treated, the root causes are not treated, and the cost is relatively high; in addition, the existing buccal tablets are mostly in the shape of a nail cover, the buccal tablets need to stay in the oral cavity for a long time in the using process, the buccal tablets can be easily swallowed carelessly if a person speaks, moves or is frightened in the process, the buccal tablets are extremely easy to be clamped in the esophagus or trachea, and serious suffocation or even life threatening can be caused.
Disclosure of Invention
The invention aims to provide a bletilla striata buccal tablet to solve the problem that the existing buccal tablet is easy to swallow by mistake in the using process.
In order to achieve the purpose, the basic technical scheme of the invention is as follows: a bletilla striata buccal tablet comprises a membrane coat, an instant layer, a slow dissolving layer, a core body and an anti-swallow mechanism, wherein the anti-swallow mechanism comprises a positioning card, a pull wire and an anti-swallow knot, the positioning card is arc-shaped and flaky, one end of the pull wire is fixed in the middle of the inner side of the arc surface of the positioning card, the other end of the pull wire is fixed on the anti-swallow knot, the membrane coat, the instant layer, the slow dissolving layer and the core body are sequentially coated on the anti-swallow knot from outside to inside, the anti-swallow knot comprises two co-diameter rings which are arranged in a right-angle crossed manner, and; the membrane coat is prepared by mixing bletilla hyacinthine gum and glutinous rice slurry, the instant layer is prepared by mixing bletilla hyacinthine powder, rhizoma corydalis powder, radix Glycyrrhizae powder, sodium bicarbonate and tartaric acid, the slow-dissolving layer is prepared by mixing bletilla hyacinthine powder, fructus Zanthoxyli powder, herba Taraxaci powder, bletilla hyacinthine gum, edible gelatin and agar, and the core body is prepared by mixing bletilla hyacinthine powder, Mel and Corii Sus Domestica jelly.
The principle and the advantages of the scheme are as follows: in practical application, the film coat, the instant layer, the slow dissolving layer and the core body form a main body of the buccal tablet treatment, and the swallowing prevention mechanism is used as a structure for preventing the buccal tablet from being swallowed by mistake. The arc-shaped sheet-shaped positioning card has a shape similar to the tooth and periodontal contour, can be well attached to the outer side of the tooth without influencing the normal movement of the tooth, tongue and lips, and can limit the swallow-proof structure and the buccal tablet through the blocking of the tooth; the pull wire is fixed in the middle of the inner side of the cambered surface of the positioning clamping piece, so that one end of the pull wire connected with the positioning clamping piece after the positioning clamping piece is positioned can not be tightly attached to gum in a tooth gap under the support of the positioning clamping piece, and the situation that the buccal tablet is moved in the oral cavity to bring the pull wire to cause friction damage to the gum in the tooth gap in the use process can be avoided; the anti-swallow knot is used as a supporting structure of various medicines in the buccal tablet on one hand, and is connected with the pull wire to be used as a connecting component for preventing the buccal tablet from being swallowed by mistake on the other hand, the co-diameter rings which are arranged in a right-angle cross way can support and structurally reinforce the core body coated outside the anti-swallow knot, the buccal tablet can be prevented from cracking and crushing from the core body to the outside in the using process, and the shape of the buccal tablet can be kept complete, so that the service life of the buccal; the stay wire is fixed at the cross point of the same-diameter ring, so that the stay wire is connected to the position with the most stable structure and the highest strength on the anti-swallow knot, and the situation that the buccal tablet falls off from the anti-swallow mechanism due to the fact that the anti-swallow knot is loosened from the stay wire can be effectively prevented.
The film coating made of bletilla striata gum and glutinous rice paste can protect the surface of the buccal tablet, and the bletilla striata gum and the glutinous rice paste have good viscosity, so that the buccal tablet can keep the integrity of the appearance; the instant layer prepared by mixing the bletilla striata powder, the rhizoma corydalis powder, the licorice powder, the sodium bicarbonate and the tartaric acid has a certain effervescent effect, after the membrane is dissolved by saliva, the sodium bicarbonate and the tartaric acid can rapidly carry out an effervescent reaction with the saliva to decompose the instant layer and disperse the decomposed instant layer into an oral cavity, an esophagus or a respiratory tract for treatment, the bletilla striata powder, the rhizoma corydalis powder and the licorice powder can carry out hemostasis, detumescence and granulation treatment on wounds in the oral cavity, the esophagus, the stomach and the respiratory tract, and the licorice powder can also neutralize the bitter taste brought by a part of the bletilla striata powder; the slow dissolving layer adopts bletilla striata gum as a main body, a slowly dissolved colloid carrier which can be deformed by chewing and can be formed by matching edible gelatin and agar, the slowly dissolved colloid carrier can stay in an oral cavity for a long time, bletilla striata powder, paprika powder and dandelion powder are mixed in the colloid carrier and gradually dispersed in the oral cavity in the chewing process to continuously treat the oral cavity, the paprika powder and the dandelion powder can further promote the effects of diminishing inflammation, relieving pain and diminishing swelling of the oral cavity, and meanwhile, the colloid carrier can be deformed in the oral cavity by chewing and attached to the wound of the oral cavity to carry out fixed-point covering treatment, so that the treatment effect is better; the core adopts the tuber of hyacinth bletilla powder, honey and pigskin freeze and mix and make, the tuber of hyacinth bletilla powder can continuously carry out oral treatment, honey and pigskin freeze can adjust and alleviate the instant layer, the bitter taste that the medicine in the slowly-dissolved layer brought, and provide certain nutrition and promote the treatment, the pigskin is frozen and is had higher stickness, can form stable core, can also cover powder and continuously treat at the oral cavity wall after dissolving in the oral cavity, can supply collagen simultaneously and promote the oral cavity, the inner wall top layer cell of esophagus is restoreed, make the buccal tablet have better treatment.
The tuber of hyacinth bletilla buccal tablet that this scheme provided both can avoid in the use not good or the card of curative effect to have the condition of the potential safety hazard of suffocating in esophagus, trachea by preventing swallowing the mechanism by the mistake, it is safe convenient more to use, can treat viscera such as esophagus, respiratory tract, stomach through instant layer in addition, can continuously carry out fixed point cover treatment to the oral cavity through slowly dissolving the layer, can improve the impression of using and the oral cavity environment after using through the core, the treatment that has showing, excellent in use effect.
Preferably, the first scheme is an improvement of the basic scheme, and the mass part ratio of the bletilla striata gum to the glutinous rice pulp in the membrane is 3: 1. The film coating with the optimized proportion has moderate viscosity, stable structure, better protective effect on the surface of the buccal tablet and certain treatment effect.
In a second preferred scheme, as an improvement of the first preferred scheme, the mass part ratio of the bletilla striata powder, the rhizoma corydalis powder, the licorice powder, the sodium bicarbonate and the tartaric acid in the instant layer is 2-4: 2:1:1: 0.7. The bletilla striata powder, the rhizoma corydalis powder and the licorice powder in the instant layer are taken as main bodies and the sodium bicarbonate and the tartaric acid are taken as effervescent disintegrating agents preferably according to the proportion, so that the bletilla striata powder, the rhizoma corydalis powder and the licorice powder can be decomposed and dispersed in an oral cavity at a certain speed in the using process, and the tablet can not be decomposed due to unstable structure caused by too fast decomposition.
And in the third preferred scheme, as an improvement of the second preferred scheme, the mass part ratio of the bletilla striata powder, the pepper powder, the dandelion powder, the bletilla striata gum, the edible gelatin and the agar in the slow dissolving layer is 3-5: 1-2: 1.5: 6-8: 4: 3. The preferred proportion enables bletilla striata gum as a main body to form a gum carrier which can be slowly absorbed to carry the medicine powder, and meanwhile, the proportion of the bletilla striata gum, the bletilla striata powder and other medicines can better exert respective medicine effects, so that the traditional Chinese medicine has better treatment effect.
Preferably, the fourth scheme is an improvement of the second scheme, and the mass part ratio of the bletilla striata powder, the honey and the pigskin jelly in the core body is 1:2: 5. The optimal proportion ensures that the pigskin jelly as a main body can form a core body with certain strength and viscosity, is not easy to decompose and break, can be well adhered with the swallowing prevention mechanism, ensures that the instant layer and the slow-dissolving layer which are wrapped on the outer layer are not easy to fall off from the swallowing prevention mechanism, and ensures that the buccal tablet has better swallowing prevention effect.
Preferably scheme five, as an improvement of basic scheme, integrated into one piece has a plurality of outward radial branch on the ring of the same footpath, and the surface of branch is equipped with a plurality of ratchet form archs. The core, the slow dissolving layer and the instant dissolving layer can be internally supported and connected through the supporting rods and the ratchet-shaped protrusions, so that the core, the slow dissolving layer and the instant dissolving layer are respectively and internally connected with each other better, the interlayer structure of the buccal tablet is more stable, and the buccal tablet is not easy to integrally disintegrate and disperse.
The preferable scheme is six, as an improvement of the preferable scheme is five, the diameter of the support rod is 0.1-0.3 mm, the support rod comprises a long support rod and a short support rod, the length of the long support rod is 3-4 mm, the length of the short support rod is half of the length of the long support rod, the stay wire is polyester polylith, and the diameter of the stay wire is 0.5-0.8 mm. The structure that adopts long branch, short branch can carry out the reinforced connection of interlaminar structure to the buccal tablet on the thickness of difference, and the guy that this size range's polyester silk was made can make things convenient for easy slip into the slit between the teeth, can not cause the damage to the tooth, can not extrude the tooth and cause the tooth not hard up, and nontoxic harmless, it is more safe convenient to use.
Drawings
Fig. 1 is a schematic structural diagram of a bletilla striata buccal tablet in embodiment 1 of the present invention.
Detailed Description
The present invention will be described in further detail below by way of specific embodiments:
reference numerals in the drawings of the specification include: the device comprises a positioning clamp 1, a stay wire 2, a same-diameter ring 3, a long support rod 4, a core body 5, a slow dissolving layer 6, a fast dissolving layer 7 and a film coat 8.
The embodiment is basically as shown in the attached figure 1: a bletilla striata buccal tablet comprises a membrane coat 8, an instant layer 7, a slow dissolving layer 6, a core body 5 and an anti-swallow mechanism, wherein the anti-swallow mechanism comprises a positioning clamp 1, a stay wire 2 and an anti-swallow knot, the positioning clamp 1 is in an arc sheet shape, the stay wire 2 is polyester yarn, the diameter of the stay wire 2 is 0.5mm, one end of the stay wire 2 is fixed in the middle of the inner side of the arc surface of the positioning clamp 1, the other end of the stay wire 2 is fixed on the anti-swallow knot, the membrane coat 8, the instant layer 7, the slow dissolving layer 6 and the core body 5 are sequentially coated on the anti-swallow knot from outside to inside, the anti-swallow knot comprises two co-diameter rings 3 which are arranged in a right-angle cross mode, the stay wire 2 is bound and fixed on a cross point of the two co-diameter rings 3, a plurality of outward radial support rods are integrally formed on each co-diameter ring 3, a plurality of ratchet-diameter bulges, the length of the long strut 4 is 3mm, and the length of the short strut is half of that of the long strut 4; the film coat 8 is prepared by mixing bletilla striata gum and glutinous rice pulp in a mass part ratio of 3:1, the instant layer 7 is prepared by mixing bletilla striata powder, rhizoma corydalis powder, licorice powder, sodium bicarbonate and tartaric acid in a mass part ratio of 2:2:1:1:0.7, the slow dissolving layer 6 is prepared by mixing bletilla striata powder, paprika powder, dandelion powder, bletilla striata gum, edible gelatin and agar in a mass part ratio of 3:1:1.5:6:4:3, and the core body 5 is prepared by mixing bletilla striata powder, honey and pigskin jelly in a mass part ratio of 1:2: 5.
In this embodiment, during practical application, a hole is drilled in the middle of the positioning clamp 1, a 0.5mm polyester wire is used as the pull wire 2, one end of the pull wire is bound at the intersection of the two equal-diameter rings 3 which are resistant to swallow, the other end of the pull wire passes through the hole in the positioning clamp 1 and then is knotted and fixed, and the diameter of the excircle of the equal-diameter ring 3 is 10 mm. The core body 5 is wrapped on the surface which is prevented from being swallowed, the core body 5 is prevented from submerging the long supporting rod 4 in the wrapping process, then the outside of the core body 5 is wrapped with a slow dissolving layer 6 material, the top end of the long supporting rod 4 is located outside the slow dissolving layer 6 after the wrapping, then the outside of the slow dissolving layer 6 is wrapped with an instant dissolving layer 7, the instant dissolving layer 7 wraps the top end of the long supporting rod 4, and then the instant dissolving layer 7 is wrapped with a film coat 8 and then subjected to vacuum compression molding.
Example 2, this example differs from example 1 only in that the diameter of the wire 2 is 0.6mm, the diameter of the struts is 0.2mm, the struts comprise long struts 4 and short struts, the length of the long struts 4 is 3.5 mm; the quick-dissolving layer 7 is prepared by mixing bletilla striata powder, rhizoma picrorhizae powder, licorice powder, sodium bicarbonate and tartaric acid according to the mass part ratio of 3:2:1:1:0.7, and the slow-dissolving layer 6 is prepared by mixing bletilla striata powder, paprika powder, dandelion powder, bletilla striata gum, edible gelatin and agar according to the mass part ratio of 4:1.5:1.5:7:4: 3.
Example 3, this example differs from example 1 only in that the diameter of the wire 2 is 0.8mm, the diameter of the struts is 0.3mm, the struts include long struts 4 and short struts, and the length of the long struts 4 is 4 mm; the quick-dissolving layer 7 is prepared by mixing bletilla striata powder, rhizoma picrorhizae powder, licorice powder, sodium bicarbonate and tartaric acid according to the mass part ratio of 4:2:1:1:0.7, and the slow-dissolving layer 6 is prepared by mixing bletilla striata powder, paprika powder, dandelion powder, bletilla striata gum, edible gelatin and agar according to the mass part ratio of 5:2:1.5:8:4: 3.
The tuber of hyacinth bletilla buccal tablet that this scheme provided both can avoid in the use not good or the card of curative effect to have the condition of the potential safety hazard of suffocating in the esophagus, trachea by preventing swallowing the mechanism by the mistake, it is safe convenient more to use, and can be to the esophagus through instant layer 7, respiratory tract, viscera such as stomach are treated, can continuously carry out fixed point cover treatment to the oral cavity through slowly dissolving layer 6, can improve the impression of using and the oral cavity environment after using through core 5, the treatment that has showing, excellent in use effect.
The foregoing is merely an example of the present invention and common general knowledge in the art of specific structures and/or features of the invention has not been set forth herein in any way. It should be noted that, for those skilled in the art, without departing from the structure of the present invention, several changes and modifications can be made, which should also be regarded as the protection scope of the present invention, and these will not affect the effect of the implementation of the present invention and the practicability of the patent. The scope of the claims of the present application shall be determined by the contents of the claims, and the description of the embodiments and the like in the specification shall be used to explain the contents of the claims.

Claims (2)

1. The bletilla striata buccal tablet is characterized in that: the anti-swallow structure comprises a film coat, an instant layer, a slow dissolving layer, a core body and an anti-swallow mechanism, wherein the anti-swallow mechanism comprises a positioning card, a pull wire and an anti-swallow knot, the positioning card is in an arc-shaped sheet shape, one end of the pull wire is fixed in the middle of the inner side of the arc surface of the positioning card, the other end of the pull wire is fixed on the anti-swallow knot, the film coat, the instant layer, the slow dissolving layer and the core body are sequentially coated on the anti-swallow knot from outside to inside, the anti-swallow knot comprises two co-diameter rings which are arranged in a right-angle crossed manner, and; a plurality of outward radial supporting rods are integrally formed on the same-diameter ring, and a plurality of ratchet-shaped protrusions are arranged on the surfaces of the supporting rods; the film coat is prepared by mixing bletilla striata gum and glutinous rice pulp, wherein the mass part ratio of the bletilla striata gum to the glutinous rice pulp is 3: 1; the instant layer is prepared by mixing bletilla striata powder, rhizoma corydalis powder, licorice powder, sodium bicarbonate and tartaric acid, wherein the mass part ratio of the bletilla striata powder to the rhizoma corydalis powder to the licorice powder to the sodium bicarbonate to the tartaric acid is 2-4: 2:1:1: 0.7; the slow-dissolving layer is prepared by mixing bletilla striata powder, paprika powder, dandelion powder, bletilla striata gum, edible gelatin and agar, and the mass part ratio of the bletilla striata powder, the paprika powder, the dandelion powder, the bletilla striata gum, the edible gelatin and the agar is 3-5: 1-2: 1.5: 6-8: 4: 3; the core body is prepared by mixing bletilla striata powder, honey and pigskin jelly, and the mass part ratio of the bletilla striata powder to the honey to the pigskin jelly is 1:2: 5.
2. The bletilla striata buccal tablet according to claim 1, characterized in that: the diameter of the support rod is 0.1-0.3 mm, the support rod comprises a long support rod and a short support rod, the length of the long support rod is 3-4 mm, the length of the short support rod is half of the length of the long support rod, the stay wire is polyester polylinker wire, and the diameter of the stay wire is 0.5-0.8 mm.
CN201710741453.3A 2017-08-25 2017-08-25 Bletilla striata buccal tablet Active CN107375711B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710741453.3A CN107375711B (en) 2017-08-25 2017-08-25 Bletilla striata buccal tablet

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710741453.3A CN107375711B (en) 2017-08-25 2017-08-25 Bletilla striata buccal tablet

Publications (2)

Publication Number Publication Date
CN107375711A CN107375711A (en) 2017-11-24
CN107375711B true CN107375711B (en) 2020-11-03

Family

ID=60345230

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201710741453.3A Active CN107375711B (en) 2017-08-25 2017-08-25 Bletilla striata buccal tablet

Country Status (1)

Country Link
CN (1) CN107375711B (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001072286A1 (en) * 2000-03-27 2001-10-04 Glaxosmithkline Consumer Healthcare Gmbh & Co Kg Sustained release vitamin composition
CN101966165A (en) * 2009-07-14 2011-02-09 无锡健而乐医药科技有限公司 Solid effervescent mixture for the oral absorption
CN103340833B (en) * 2013-06-03 2015-06-03 中国人民解放军第四军医大学 Fentanyl double-layer buccal tablet and preparation method thereof
CN204484792U (en) * 2015-02-09 2015-07-22 董长晓 Promote the production of body fluid health preserving jade containing part

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001072286A1 (en) * 2000-03-27 2001-10-04 Glaxosmithkline Consumer Healthcare Gmbh & Co Kg Sustained release vitamin composition
CN101966165A (en) * 2009-07-14 2011-02-09 无锡健而乐医药科技有限公司 Solid effervescent mixture for the oral absorption
CN103340833B (en) * 2013-06-03 2015-06-03 中国人民解放军第四军医大学 Fentanyl double-layer buccal tablet and preparation method thereof
CN204484792U (en) * 2015-02-09 2015-07-22 董长晓 Promote the production of body fluid health preserving jade containing part

Also Published As

Publication number Publication date
CN107375711A (en) 2017-11-24

Similar Documents

Publication Publication Date Title
CN107375711B (en) Bletilla striata buccal tablet
CN205569347U (en) Sugar -free gum that contains dendrobii officmalis caulis polysaccharide microsphere
Conrick Neem: the ultimate herb
CN103405578A (en) External powder for treating dental ulcer and preparation method thereof
CN103099881A (en) External traditional Chinese medicine composition for treating toothache
JPH04193823A (en) Pill readily crushable with teeth and easily administrable without water
RU2060033C1 (en) Agent for treatment and prophylaxis of parodontium disease and a method of its preparing
CN1149468A (en) Powder for laryngopharyngitis
CN102048880A (en) Externally applied ointment for adjuvant therapy of pharyngitis and canker sore and preparation method thereof
CN106511491B (en) A kind of composition and preparation method thereof, application, preparation
CN100566749C (en) A kind of dissolved granule and manufacture method thereof for the treatment of pharyngitis
CN103610940A (en) Traditional Chinese medicinal composition for treating toothache
Srivastava et al. Phytodentistry-An Obscure Yet Efficient Practise: A Review
CN1080565C (en) Fuyanyu (exterior-use capsule)
CN101422590A (en) Medicine that a kind of treatment is had a toothache and preparation method thereof
Rai Honey in oral diseases: Ayurvedic and unani perspective
CN109394599A (en) A kind of tooth powder
CN111905025B (en) Traditional Chinese medicine composition for treating oral ulcer, stopping bleeding, relieving pain and diminishing inflammation and preparation method and application thereof
JPH0466205B2 (en)
CN107137458A (en) A kind of Uygur medicine composition broken wall preparation and production method for treating mouth disease
CN1125649C (en) Medicine for treating odontopathy
Narang et al. An Ayurvedic Preventive And Curative Approach To Periodontitis/Pyorrhea
Natto Herbs and Oral Health
Fawzi et al. Theoretical substantiation of active substances’ choice in dental gel “dentavir-phyto”
CN104367780A (en) Novel enteromorpha prolifera oral ulcer treatment patch

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant