JPH04193823A - Pill readily crushable with teeth and easily administrable without water - Google Patents
Pill readily crushable with teeth and easily administrable without waterInfo
- Publication number
- JPH04193823A JPH04193823A JP2324987A JP32498790A JPH04193823A JP H04193823 A JPH04193823 A JP H04193823A JP 2324987 A JP2324987 A JP 2324987A JP 32498790 A JP32498790 A JP 32498790A JP H04193823 A JPH04193823 A JP H04193823A
- Authority
- JP
- Japan
- Prior art keywords
- pill
- menthol
- water
- readily
- title
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000006187 pill Substances 0.000 title claims abstract description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title abstract description 9
- 239000000843 powder Substances 0.000 claims abstract description 17
- NOOLISFMXDJSKH-KXUCPTDWSA-N (-)-Menthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@H]1O NOOLISFMXDJSKH-KXUCPTDWSA-N 0.000 claims abstract description 9
- DTGKSKDOIYIVQL-NQMVMOMDSA-N (+)-Borneol Natural products C1C[C@]2(C)[C@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-NQMVMOMDSA-N 0.000 claims abstract description 5
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 5
- 239000000796 flavoring agent Substances 0.000 claims abstract description 5
- 230000001256 tonic effect Effects 0.000 claims abstract description 5
- 240000004670 Glycyrrhiza echinata Species 0.000 claims abstract description 3
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 claims abstract description 3
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims abstract description 3
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 claims abstract description 3
- 235000016639 Syzygium aromaticum Nutrition 0.000 claims abstract description 3
- 244000223014 Syzygium aromaticum Species 0.000 claims abstract description 3
- 229940010454 licorice Drugs 0.000 claims abstract description 3
- 210000003296 saliva Anatomy 0.000 claims abstract 3
- 230000003248 secreting effect Effects 0.000 claims abstract 2
- 244000223760 Cinnamomum zeylanicum Species 0.000 claims description 5
- 235000017803 cinnamon Nutrition 0.000 claims description 5
- 235000013355 food flavoring agent Nutrition 0.000 claims description 2
- 235000015961 tonic Nutrition 0.000 claims 2
- 229960000716 tonics Drugs 0.000 claims 2
- 244000299790 Rheum rhabarbarum Species 0.000 claims 1
- 235000009411 Rheum rhabarbarum Nutrition 0.000 claims 1
- 238000010521 absorption reaction Methods 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 230000007721 medicinal effect Effects 0.000 claims 1
- 239000003814 drug Substances 0.000 abstract description 7
- 235000019634 flavors Nutrition 0.000 abstract 3
- 241000271307 Aquilaria malaccensis Species 0.000 abstract 1
- 241000723347 Cinnamomum Species 0.000 abstract 1
- 230000000954 anitussive effect Effects 0.000 abstract 1
- 239000003907 antipyretic analgesic agent Substances 0.000 abstract 1
- 229940124584 antitussives Drugs 0.000 abstract 1
- 230000000747 cardiac effect Effects 0.000 abstract 1
- ZZVUWRFHKOJYTH-UHFFFAOYSA-N diphenhydramine Chemical compound C=1C=CC=CC=1C(OCCN(C)C)C1=CC=CC=C1 ZZVUWRFHKOJYTH-UHFFFAOYSA-N 0.000 abstract 1
- 239000003172 expectorant agent Substances 0.000 abstract 1
- 230000003419 expectorant effect Effects 0.000 abstract 1
- 239000011888 foil Substances 0.000 abstract 1
- 210000004877 mucosa Anatomy 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 210000002784 stomach Anatomy 0.000 abstract 1
- 229940079593 drug Drugs 0.000 description 4
- 229940041616 menthol Drugs 0.000 description 3
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 2
- 244000000626 Daucus carota Species 0.000 description 2
- 235000002767 Daucus carota Nutrition 0.000 description 2
- 239000007884 disintegrant Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000008187 granular material Substances 0.000 description 2
- 229940088417 precipitated calcium carbonate Drugs 0.000 description 2
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 description 2
- 239000003826 tablet Substances 0.000 description 2
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 239000004288 Sodium dehydroacetate Substances 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- 239000002386 air freshener Substances 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 description 1
- 229940116229 borneol Drugs 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 229940124579 cold medicine Drugs 0.000 description 1
- 239000012024 dehydrating agents Substances 0.000 description 1
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- NFLGAXVYCFJBMK-UHFFFAOYSA-N isomenthone Natural products CC(C)C1CCC(C)CC1=O NFLGAXVYCFJBMK-UHFFFAOYSA-N 0.000 description 1
- 229940015700 menthol 15 mg Drugs 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 229940118683 ox bile extract Drugs 0.000 description 1
- 235000008160 pyridoxine Nutrition 0.000 description 1
- 239000011677 pyridoxine Substances 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 229940079839 sodium dehydroacetate Drugs 0.000 description 1
- 235000019259 sodium dehydroacetate Nutrition 0.000 description 1
- DSOWAKKSGYUMTF-GZOLSCHFSA-M sodium;(1e)-1-(6-methyl-2,4-dioxopyran-3-ylidene)ethanolate Chemical compound [Na+].C\C([O-])=C1/C(=O)OC(C)=CC1=O DSOWAKKSGYUMTF-GZOLSCHFSA-M 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 229940011671 vitamin b6 Drugs 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Description
【発明の詳細な説明】
（産業上の利用分野）
この発明は従来ある医薬品を水をもって服用するかわり
に口中にて噛みくだくことにより、口中清涼剤の如くに
、口中をされやかにして、内服を容易にさせることによ
り目的を達成させるもので、この発明は一般薬等（かぜ
薬、強壮保健薬）をこの丸剤として容易に飲みやすく、
水なしでも何処でも、手軽に服用できるようにしたもの
である。[Detailed Description of the Invention] (Industrial Application Field) This invention enables conventional medicines to be chewed in the mouth instead of being taken with water, making the mouth feel refreshed like a mouth freshener. This purpose is achieved by making it easier to take internally, and this invention makes it possible to easily take general medicines (cold medicines, tonic health medicines) as pills.
It is designed to be easily taken anywhere, even without water.
（従来の技術）
従来、内服用薬の、錠剤、顆粒剤、粉末剤は水がない場
合は容易に服用することが困難であった。(Prior Art) Conventionally, tablets, granules, and powders for internal use have been difficult to take without water.
（発明が解決しようとする課題）
この発明は内服用薬の錠剤、顆粒剤、粉末剤は味の点又
は、大きさの点で水なしでは飲みにくい事を、解消しよ
うとするもので、本発明はこれらの欠点を解決するため
に発明されガものである。(Problems to be Solved by the Invention) This invention attempts to solve the problem that oral medicine tablets, granules, and powders are difficult to swallow without water due to taste or size. The invention has been devised to overcome these drawbacks.
（課題を解決するための手段）
（イ）丸剤の剤形の直径を３關より６ｍｍ以内の大形と
して硬度平均３ｋｇより５ｋｇ以内とする。(Means for Solving the Problems) (a) The diameter of the pill form is set to a large size within 6 mm from the third diameter, and the average hardness is within 5 kg from 3 kg.
（ロ）矯味剤として薬事法に適合する範囲内のし一メン
トール（Ｎ荷脳）またはｄｌ−メントール（合成薄荷脳
）を５％以内及びｄ−ボルネオール２％以内を用いる。(b) As a flavoring agent, use 5% or less of menthol (N-menthol) or dl-menthol (synthetic menthol) and 2% or less of d-borneol within a range that complies with the Pharmaceutical Affairs Law.
その他桂皮末または肉桂末を１０％以内及び丁字、助香
、甘草等を適宜処方する。In addition, cinnamon powder or cinnamon powder in an amount of 10% or less, and clove, sucrose, licorice, etc., may be prescribed as appropriate.
（ハ）丸剤の乾燥度は含有水分１０〜１５％以内に保っ
たものとする。(c) The dryness of the pills shall be maintained within 10 to 15% of moisture content.
（ニ）丸剤の外面には適宜 箔打ち或はラック掛、また
はフィルムコーチングをする。(d) The outer surface of the pill should be foil-plated, racked, or film-coated as appropriate.
（作用〉
本発明は従来の九剤より容易に口中にて崩壊、咥下しや
すく、−煎薬特に保健薬、栄養業が従来錠剤、顆粒剤、
丸刑としてドリンク剤より飲みにくい点を改良して、非
常に容易に水なしで服用出来るようにした物である。(Function) The present invention disintegrates in the mouth more easily than the conventional nine tablets, and is easier to swallow.
It is difficult to swallow as a pill compared to a drink pill, but has been improved so that it can be taken very easily without water.
（実施例） 以下本発明の実施例について説明する。(Example) Examples of the present invention will be described below.
■（作り方）
処方例 強心五府薬
ゴオウ ５■ニンジン末
８０ ｍ１４ジンコウ末
３０ｍｇ牛胆汁エキス末 ４
０＋ｎｇガジュツ末 ５０ｍｇケイ
ヒ末 ４０ ｍｇ芳香剤 ｄ−
ボルネオール ３ｍｇ、堝昧剤 Ｌ−
メントール １５ｍｇデＩ−デフ−酸
ナトリウム ８ 、３ ｍｇ崩壊剤 沈降炭
酸カルシウム “１５ｍｇ／／ ＥＣＧ
’１３．７’ｍｇ結合剤
Ｃ，ＭＣ６ｍｇ
／／ 寒 梅 粉
１０ｍｇ１日分 １２粒と、して １粒 ５０ｍｇ
各粉末を８０〜１００目フルイで通し、Ｌ−メントール
、ｄ−ボルネオールと一緒にして充分に混合する、混合
したｆｉｇ、′″繍７シ２５０ｍ１を加え練合して水分
割合を５０％以内とする、練合した物を製九機により製
丸して後、乾燥しツヤ打は小量のアラビア溶液にタルク
を加える、その後箔打ちラックを小量掛は銀箔又は金箔
をまぶし仕上げる、
高度平均３ｋｇとする。■(How to make it) Prescription example: Strong Gofu Yakugou 5■ Carrot powder
80 m14 Jinko powder
30mg ox bile extract powder 4
0+ng Gajutu powder 50mg Cinnamon powder 40mg Air freshener d-
Borneol 3mg, dehydrating agent L-
Menthol 15mg Sodium deI-defuate 8,3 mg Disintegrant Precipitated calcium carbonate 15mg// ECG
'13.7'mg binder
C, MC6mg // Cold plum powder
12 tablets of 10mg per day and 1 tablet of 50mg
Pass each powder through a sieve with 80 to 100 meshes, mix thoroughly with L-menthol and d-borneol, add 250ml of the mixed fig, '''7, and knead until the moisture content is within 50%. After the kneaded product is made into balls using a nine-machine machine, talc is added to a small amount of Arabic solution for drying and gloss, and then a small amount of silver or gold leaf is sprinkled on a foiling rack. The weight shall be 3 kg.
■（作り方）のと同様にて作る。■Make it in the same way as (how to make).
処方例・ 保険強壮薬゛処方
オウセイ ２ ’Ｏｍｇロクジョ
ウ ２０ ’ｍｇゴオウ
５ｍｇオカリ草末
４０’ｍｇニンジン末 ３００ ｍ
ｇチアミンＮＤＳ ２ｏ■ピリドキシン
１９ｍｇ芳香剤 ｄ−ボルネオール
３■矯昧剤 Ｌ−メントール
２０１Ｉ１ｇデヒドロ酢酸ナトリウム ８
．３■崩壊剤 ＥＣＧ ”１３．７■
〃 沈降炭酸カルシウム １５■結合剤
ＣＭＣ” ６ｍｇ
／／ 寒梅粉 １０呵
合 計 ５００ ｍｇ
１日分 １０粒として １粒 ５０■（使い方）
本発明は以上の様な構成であるのでこれを使用するとき
は、口中にて容易に崩壊し、水なしでも服用することが
、出来る。Prescription example/ Insurance tonic 2 'Omg Rokujou 20'mg Gouou
5mg Okari grass powder
40'mg carrot powder 300 m
gThiamin NDS 2o■Pyridoxine 19mgFragrance agent d-borneol 3■Corrigendant L-menthol
201I1g Sodium dehydroacetate 8
．． 3■ Disintegrant ECG "13.7■
〃 Precipitated calcium carbonate 15 ■ Binder
CMC" 6mg // Kanbai powder 10 pieces Total 500 mg 1 day 10 tablets 1 tablet 50■ (How to use) Since the present invention has the above structure, when using it, it disintegrates easily in the mouth. However, it can be taken without water.
（発明の効果）
従来の九剤ではそのまま服用が出来にくい物が多かった
が、本発明により服用が容易になり水なしでも何処でも
手軽に、。(Effect of the invention) Many of the conventional nine drugs were difficult to take as they are, but the present invention makes it easier to take them anywhere without water.
内服して効果がすみやかに発現する。When taken internally, the effects appear quickly.
特゛許出願人 松井製薬株式会社Patent applicant: Matsui Pharmaceutical Co., Ltd.
Claims (1)
３０ｍｇ〜６０ｍｇとして硬度平均３．５ｋｇ〜５ｋｇ
以内とし、口中で歯にて容易に崩壊して、医薬品中滋養
強壮剤、五疳強心剤などに矯味薬、矯臭薬を加えて唾液
を分泌させて容易に嚥下することができ、同時に口中粘
膜より体内吸収もすみやかにさせ、薬効を的確に作用さ
せて、 （ロ）矯味薬として薬事法に適合する範囲内のＬ−メン
トール（薄荷脳）５％以内及びｄ−ボルネオール（龍脳
）２％以内を用いるその他桂皮末または肉桂末を１０％
以内で処方に加え、その他丁字、茴香、甘草等を適宜加
えて、（ハ）これは胃腸薬、かぜ薬、解熱鎮痛薬、鎮咳
去痰薬等の厚生省医薬品製造基準の処方製剤等の他に医
薬部外品にも用いることとする。[Claims] (a) This pill has a diameter of 3 mm to 6 mm and a grain weight of 30 mg to 60 mg, and an average hardness of 3.5 kg to 5 kg.
It can be easily swallowed by adding saliva to the pharmaceutical tonics, pentagonal tonics, etc., and it can be easily swallowed by secreting saliva. (b) L-menthol (L-menthol) within 5% and d-borneol (Ryunan) within 2%, which is within the range of compliance with the Pharmaceutical Affairs Law as a flavoring agent, with rapid absorption in the body and accurate medicinal effects. 10% cinnamon powder or cinnamon powder
In addition to prescriptions within the following, other ingredients such as clove, rhubarb, and licorice may also be added as appropriate. It will also be used for external products.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2324987A JPH04193823A (en) | 1990-11-27 | 1990-11-27 | Pill readily crushable with teeth and easily administrable without water |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2324987A JPH04193823A (en) | 1990-11-27 | 1990-11-27 | Pill readily crushable with teeth and easily administrable without water |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH04193823A true JPH04193823A (en) | 1992-07-13 |
Family
ID=18171868
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2324987A Pending JPH04193823A (en) | 1990-11-27 | 1990-11-27 | Pill readily crushable with teeth and easily administrable without water |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH04193823A (en) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006036694A (en) * | 2004-07-27 | 2006-02-09 | Nakamurado:Kk | Method for producing fermentation prepared liquid of rice bran or the like |
| WO2006111830A2 (en) * | 2005-04-20 | 2006-10-26 | Council Of Scientific And Industrial Research | Functional aphrodisiac rolled herbal bidis and cigarettes |
| JP2006342189A (en) * | 2006-09-28 | 2006-12-21 | Rohto Pharmaceut Co Ltd | Intraoral dissolution type or chewable solid internal medicine composition containing medicine having bitterness |
| JPWO2006129668A1 (en) * | 2005-05-30 | 2009-01-08 | 明治製菓株式会社 | Sugar-coated pills |
| JP2010174028A (en) * | 2010-03-18 | 2010-08-12 | Rohto Pharmaceut Co Ltd | Intraorally soluble or chewing solid internal pharmaceutical composition containing bitter agent |
| CN102526397A (en) * | 2012-01-12 | 2012-07-04 | 高新华 | Medicament for treating salivation |
| JP2013028647A (en) * | 2012-11-06 | 2013-02-07 | Rohto Pharmaceutical Co Ltd | Intraorally soluble or chewable solid internal pharmaceutical composition containing bitter drug |
| JP2013194036A (en) * | 2012-03-22 | 2013-09-30 | Kobayashi Pharmaceutical Co Ltd | Pharmaceutical composition |
| CN104886579A (en) * | 2015-06-17 | 2015-09-09 | 吉林人参研究院 | Red ginseng pellet and preparation method |
| CN114703109A (en) * | 2022-05-10 | 2022-07-05 | 山东中医药大学 | Bovine bile-tolerant bezoar transformation bacterium screening culture medium, preparation method and application |
-
1990
- 1990-11-27 JP JP2324987A patent/JPH04193823A/en active Pending
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006036694A (en) * | 2004-07-27 | 2006-02-09 | Nakamurado:Kk | Method for producing fermentation prepared liquid of rice bran or the like |
| WO2006111830A2 (en) * | 2005-04-20 | 2006-10-26 | Council Of Scientific And Industrial Research | Functional aphrodisiac rolled herbal bidis and cigarettes |
| WO2006111830A3 (en) * | 2005-04-20 | 2007-04-05 | Council Scient Ind Res | Functional aphrodisiac rolled herbal bidis and cigarettes |
| JPWO2006129668A1 (en) * | 2005-05-30 | 2009-01-08 | 明治製菓株式会社 | Sugar-coated pills |
| JP2006342189A (en) * | 2006-09-28 | 2006-12-21 | Rohto Pharmaceut Co Ltd | Intraoral dissolution type or chewable solid internal medicine composition containing medicine having bitterness |
| JP2010174028A (en) * | 2010-03-18 | 2010-08-12 | Rohto Pharmaceut Co Ltd | Intraorally soluble or chewing solid internal pharmaceutical composition containing bitter agent |
| CN102526397A (en) * | 2012-01-12 | 2012-07-04 | 高新华 | Medicament for treating salivation |
| JP2013194036A (en) * | 2012-03-22 | 2013-09-30 | Kobayashi Pharmaceutical Co Ltd | Pharmaceutical composition |
| JP2013028647A (en) * | 2012-11-06 | 2013-02-07 | Rohto Pharmaceutical Co Ltd | Intraorally soluble or chewable solid internal pharmaceutical composition containing bitter drug |
| CN104886579A (en) * | 2015-06-17 | 2015-09-09 | 吉林人参研究院 | Red ginseng pellet and preparation method |
| CN114703109A (en) * | 2022-05-10 | 2022-07-05 | 山东中医药大学 | Bovine bile-tolerant bezoar transformation bacterium screening culture medium, preparation method and application |
| CN114703109B (en) * | 2022-05-10 | 2023-09-01 | 山东中医药大学 | Bezoar transformation bacteria screening culture medium capable of tolerating oxgall, preparation method and application |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TW586941B (en) | Quickly disintegratable pharmaceutical composition | |
| TWI376243B (en) | Oral disintegrating tablet | |
| JPH01503070A (en) | Drug sustained release matrices and methods | |
| JPH06502194A (en) | Rapidly disintegrating multiparticulate tablet | |
| CN108969490A (en) | Rapid dispersion particle, oral disnitegration tablet and method | |
| RU2153337C2 (en) | Paracetamol and domperidone tablet with film coating | |
| Ubhe et al. | A brief overview on tablet and it’s types | |
| Rathod et al. | Medicated lozenges as an easy to use dosage form | |
| JP2002514212A (en) | Cefadroxyl monohydrate tablet formulation | |
| JP4903382B2 (en) | Effervescent oral dosage form | |
| US3524910A (en) | Sustained relief analgesic compositions | |
| JPH04193823A (en) | Pill readily crushable with teeth and easily administrable without water | |
| JPH0729916B2 (en) | Pharmaceutical composition having analgesic properties | |
| RU2563190C2 (en) | Medication based on dry extracts of medicinal plants and method of obtaining thereof (versions) | |
| JP2001010977A (en) | Composition for oral administration | |
| JPH02188523A (en) | Remedy for apnea in sleeping | |
| Jaiswani et al. | Sublingual tablets: an overview | |
| EP4255443A1 (en) | Stable semi-solid chewable gel compositions and methods of making and using thereof | |
| JP2000095707A (en) | Oral dissolution type or chewing type solid internal medicine composition containing medicine having bitterness | |
| JP2001139469A (en) | Novel sustained release preparation composite | |
| KR20060116082A (en) | A double-layer dosage form containing vitamin c and common cold therapeutic agent and a method of preparing the dosage form | |
| US20180318226A1 (en) | Drug Delivery with Orally Dissolving Capsules | |
| RU2166937C1 (en) | Paracetamol-base drug | |
| JP2003095981A (en) | Medicine composition | |
| JP2010174028A (en) | Intraorally soluble or chewing solid internal pharmaceutical composition containing bitter agent |