CN107375671A - A kind of pill medicine and preparation method that can effectively treat cough - Google Patents
A kind of pill medicine and preparation method that can effectively treat cough Download PDFInfo
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- CN107375671A CN107375671A CN201710633782.6A CN201710633782A CN107375671A CN 107375671 A CN107375671 A CN 107375671A CN 201710633782 A CN201710633782 A CN 201710633782A CN 107375671 A CN107375671 A CN 107375671A
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- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A61K36/17—Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8964—Anemarrhena
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8965—Asparagus, e.g. garden asparagus or asparagus fern
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8966—Fritillaria, e.g. checker lily or mission bells
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8968—Ophiopogon (Lilyturf)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
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Abstract
The invention belongs to field of traditional Chinese, it is therefore an objective to which a kind of pill medicine that can effectively treat cough provided according to the understanding mechanism that Chinese traditional treatment is coughed, each component and its mass parts ratio of the medicine are as follows:25~100g of Chinese ephedra, 60~150g of the tuber of dwarf lilyturf, 30~120g of bulbus fritillariae cirrhosae, 90~160g of loguat leaf, 60~150g of asparagus fern, 50~100g of aster, 50~120g of pappy shell, 60~130g of the wind-weed, 30~100g of radix scutellariae, 30~150g of radix glycyrrhizae, 30~100g of Exocarpium Citri Rubrum, 0.5~1.5g of menthol, 60~150g of the root bark of white mulberry;Medicine provided by the invention is a good Chinese prescription.
Description
Technical field
The invention belongs to field of traditional Chinese, and in particular to a kind of pill medicine that can effectively treat cough, particularly supply
The pill medicine and the field of preparation method that cough patients use.
Background technology
Doctor thinks:Cough is the protectiveness respiration reflex action that human body removes secretion or foreign matter in respiratory tract.Though
So there is its favourable one side, but acutely chronic cough can cause hemorrhage from respiratory tract.It is correct to distinguish general cough and cough variant
Asthma, prevent mistaken diagnosis.
Clinical manifestation:
1. the property cough but no phlegm or amount of expectoration of cough are few, referred to as dry cough.Dry cough or irritable cough be common in it is acute or
It is pharyngo-laryngitis chronica, laryngocarcinoma, acute bronchitis initial stage, tracheal compression, foreign body in bronchus, tumor of bronchus, pleural diseases, primary
Property pulmonary hypertension and mitral stenosis etc..Cough is referred to as moist cough with expectoration, is common in chronic bronchitis, branch gas
Enlargement of pipe, pneumonia, pulmonary abscess and cavernous pulmonary tuberculosis etc..
2. the time of cough is with the sudden cough of rule often due to suction irritative gas or foreign matter, lymph node or tumour pressure
Compel caused by tracheae or bronchus crotch.Ictal cough is found in pertussis, endobraonchial tuberculosis and with cough
Bronchial astehma (variant asthma) of cardinal symptom etc..Long-term chronic is coughed, and is more common in chronic bronchitis, bronchus expands
, pulmonary abscess and pulmonary tuberculosis.Nocturnal cough is common in left heart failure and lunger, the reason for causing nocturnal cough, may
Increase with the exacerbation of night pulmonary venous pleonaemia and vagal excitatory relevant.
3. the characteristics of tone color of cough refers to cough sound.Such as 1. cough sound is hoarse, mostly the inflammation of vocal cords or tumour pressure
Caused by urgent recurrent nerve;2. crow sample is coughed, continuous paroxysmal play cough is shown as with lofty tone air-breathing echo, is more common in one hundred days
Cough, epiglottis, throat's illness or tracheal compression;3. metallic sound is coughed, it is common in because mediastinal tumor, aortic aneurysm or bronchiolar carcinoma are straight
Connect the cough caused by tracheas suppressed;4. cough sound is humble or powerless, it is weak to see severe emphysema, paralysis vocal cord and extreme
Person.
So, it is that those skilled in the art will urgently solve with regard to how to find a kind of Chinese medicine composition for imitating treatment cough
Certainly the problem of.
The content of the invention
With the continuous development of China's traditional Chinese medicine, in treatment cough, people gradually appreciate Chinese traditional treatment cough
The advantages of coughing, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, for the cough of existing western medical treatment
Present situation, the purpose of the present invention is to be to provide a kind of pill medicine that can effectively treat cough, extensive early to solve cough patients
The problem of rehabilitation health.The medicine is using common Chinese medicine as raw material, by selecting rational medicine and mass parts ratio, for treating
Above-mentioned cough.
To reach the purpose of foregoing invention, the technical solution adopted in the present invention is:Cough can effectively be treated by providing one kind
Pill medicine and preparation method, it is characterised in that each component and its mass parts of the medicine are than as follows:
25~100g of Chinese ephedra, 60~150g of the tuber of dwarf lilyturf, 30~120g of bulbus fritillariae cirrhosae, 90~160g of loguat leaf, 60~150g of asparagus fern, aster
50~100g, 50~120g of pappy shell, 60~130g of the wind-weed, 30~100g of radix scutellariae, 30~150g of radix glycyrrhizae, 30~100g of Exocarpium Citri Rubrum,
0.5~1.5g of menthol, 60~150g of the root bark of white mulberry, appropriate starch.
A kind of pill medicine and preparation method that can effectively treat cough, it is characterised in that each component of the medicine
And its mass parts are than as follows:
28~90g of Chinese ephedra, 70~130g of the tuber of dwarf lilyturf, 38~105g of bulbus fritillariae cirrhosae, 100~140g of loguat leaf, 70~130g of asparagus fern, aster
60~90g, 60~105g of pappy shell, 60~115g of the wind-weed, 36~90g of radix scutellariae, 38~130g of radix glycyrrhizae, 36~90g of Exocarpium Citri Rubrum, peppermint
0.8~1.3g of brain, 70~130g of the root bark of white mulberry, appropriate starch.
A kind of pill medicine and preparation method that can effectively treat cough, it is characterised in that the medicine of " preferred plan "
The each component and its mass parts of thing are than as follows:
Chinese ephedra 80g, tuber of dwarf lilyturf 115g, bulbus fritillariae cirrhosae 95g, loguat leaf 120g, asparagus fern 115g, aster 80g, pappy shell 95g, the wind-weed
100g, radix scutellariae 80g, radix glycyrrhizae 115g, Exocarpium Citri Rubrum 80g, menthol 1g, root bark of white mulberry 115g, appropriate starch.
A kind of pill medicine and preparation method that can effectively treat cough, it is characterised in that methods described includes following step
Suddenly it is prepared:
A, in addition to starch, after above-mentioned raw materials Chinese medicine is picked impurity, dust and dried, it is ground into superfine end according to mass parts ratio and treats
With;
B, the method for preparing Chinese kmedicine bolus agent according to tradition, after ground superfine myrrh thing and starch sieving, it is put into medicine device
Middle mixing is mixed, is then prepared into water-bindered pill agent(The granularity of its water-bindered pill is:3.8mm~4.0mm), and then dry, sealed packaging is
Can.
A kind of pill medicine and preparation method that can effectively treat cough, it is characterised in that the instructions of taking is:Will system
The water pill medicine got ready is three times a day to take, and once a dose in the morning, afternoon and evening, dosage 6g/ times, warm water delivery service.6 days are one
The individual course for the treatment of, 1~2 course for the treatment of of taking medicine, symptom disappear, and disease obtains recovery from illness.
Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine
Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component:
Chinese ephedra, nature and flavor:It is pungent, slight bitter, warm-natured, have inducing sweat and dispelling exogenous evils, freeing lung and relieving asthma, inducing diuresis for removing edema the effect of, for treating chill
Superficies excess syndrome, fever with aversion to cold, it is lossless, headache body pain,;Heresy is stopped up in lung, Lung Qi obstruction, cough and asthma, edema caused by wind, difficult urination, wind
The disease such as arthritis with fixed pain caused by dampness pain, skin numbness and rubella itch, cloudy subcutaneous ulcer subcutaneous nodule;
The tuber of dwarf lilyturf, nature and flavor:Sweet, slight bitter, it is slightly cold, there is the effect of nourishing Yin and promoting production of body fluid, moistening lung clears away heart-fire, for treating dryness of the lung dry cough, consumptive disease
The diseases such as cough, injury thirst, vexed insomnia, Heat Diabetes, dry constipation of intestines, pharyngeal diphtheria;
Bulbus fritillariae cirrhosae, nature and flavor:It is bitter, sweet, it is slightly cold, there is the effect of clearing heat and moistening lung, preventing phlegm from forming and stopping coughing, for treating lung-heat type cough, dry cough
Few phlegm, deficiency of Yin overstrain cough, sputum streaked with blood is coughed up, control the diseases such as cough due to consumptive disease, spitting of blood of spitting, ambition Yu Jie, consumptive lung disease, lung carbuncle, larynx numbness, acute mastitis;
Loguat leaf, nature and flavor:Bitter, acrid, cold, it is nontoxic, there is the effect of removing heat from the lung to relieve cough, harmonizing stomach and lowering adverse Qi, quench the thirst, for treating lung heat phlegm
Cough, the disease such as deficiency of Yin overstrain cough, hemoptysis, bleeding from five sense organs or subcutaneous tissue, stomach hot vomiting;
Asparagus fern, nature and flavor:It is sweet, bitter, cold, there is the effect of nourishing yin to moisten dryness, clearing lung-heat are promoted the production of body fluid, for treat dryness of the lung dry cough, pertussis phlegm it is glutinous,
Dry throat and mouth, dry constipation of intestines;
Aster, nature and flavor:Acrid, bitter, warm, have moistening lung to lower qi, stopping coughing and removing phlegm the effect of, breathed with cough for treating abundant expectoration, new chronic cough is coughed,
Overstrain cough hemoptysis;
Pappy shell, nature and flavor:It is sour, flat, have astringe the lung to stop cough, puckery intestines, analgesic therapy the effect of, for treating chronic cough, chronic diarrhea, protracted dysentery, de-
Anus, have blood in stool, all pains of trusted subordinate's muscles and bones, the disease such as involuntary emission, diuresis, leukorrhea;
The wind-weed, nature and flavor:It is bitter, sweet, cold, have clearing heat-fire, fluid dryness the effect of, for treat fever caused by exogenous pathogenic factors, hyperpyrexia polydipsia,
Lung-heat type cough, osteopyrexia and fever, Heat Diabetes, dry constipation of intestines;
Radix scutellariae, nature and flavor:It is bitter, cold in nature, have clearing heat-fire, eliminating dampness removing toxic substances, hemostasis, it is antiabortive the effect of, for treating lung heat cough
Cough, the headache of high fever apoplexy coma due to blocking of the respiratory system shies epilepsy, irascibility, red eye, swell pain, jaundice with damp-heat pathogen, rush down dysentery, heat gonorrhea, hematemesis blood, uterine bleeding, fetal movement with fever, carbuncle
Swollen furunculosis illness;
Radix glycyrrhizae, nature and flavor:It is sweet, flat, have invigorating middle warmer and replenishing QI, relieving spasm to stop pain, moisten the lung and relieve the cough, purging intense heat and detonicating, coordinating the drug actions of a prescription the effect of, use
Swollen in treatment burnout deficiency of food, the thin face Huang of flesh, palpitation, stomachache loose stool, four limbs contraction, hysteria, cough and asthma, throat
Bitterly, ulcerative carbuncle swelling and pain, infant fetal toxin and medicine, food poisoning;
Exocarpium Citri Rubrum, nature and flavor:Acrid, bitter, warm, there is the effect of cold dispelling, eliminating dampness, sharp gas, dissolving phlegm, for treating cough due to wind-cold evil, larynx itches phlegm
More, dyspepsia is got sick from drinking too much wine, evil of vomitting ruffian is vexed;
Menthol, nature and flavor:It is acrid flavour, cool in nature, there is dispelling wind, heat-clearing to imitate, for treating anemopyretic cold, headache, hot eyes, throat
Swelling and pain, dentalgia, pruitus;
The root bark of white mulberry, nature and flavor:It is sweet, cold, there is the effect of removing heat from lung and relieving asthma, inducing diuresis for removing edema, for treating dyspnea and cough due to lung-heat, oedema turgor urine
Less, appearance skin edema.
Medicine of the present invention is the principle based on Chinese traditional treatment cough, is recognized from the pathomechanism according to cough and pharmacological action
For:With regard to cough, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, there is treatment effect well to above-mentioned disease
Fruit.
Embodiment
A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of above-mentioned cough, the medicine prepared using the formula
Good drug efficacy, it is quick, it is a Chinese prescription treated both principal and secondary aspect of disease, is particularly suitable for Clinical practice.With reference to the specific of the present invention
Embodiment is described in further detail:
Embodiment 1:
A kind of pill medicine that can effectively treat cough, it is characterised in that each component and its mass parts of the medicine are such as
Shown in lower:
Chinese ephedra 80g, tuber of dwarf lilyturf 115g, bulbus fritillariae cirrhosae 95g, loguat leaf 120g, asparagus fern 115g, aster 80g, pappy shell 95g, the wind-weed
100g, radix scutellariae 80g, radix glycyrrhizae 115g, Exocarpium Citri Rubrum 80g, menthol 1g, root bark of white mulberry 115g, appropriate starch.
Embodiment 2:
A kind of pill medicine that can effectively treat cough, it is characterised in that each component and its mass parts of the medicine are such as
Shown in lower:
Chinese ephedra 90g, tuber of dwarf lilyturf 130g, bulbus fritillariae cirrhosae 105g, loguat leaf 140g, asparagus fern 130g, aster 90g, pappy shell 105g, the wind-weed
115g, radix scutellariae 90g, radix glycyrrhizae 130g, Exocarpium Citri Rubrum 90g, menthol 1.3g, root bark of white mulberry 130g, appropriate starch.
Embodiment 3:
A kind of pill medicine that can effectively treat cough, it is characterised in that each component and its mass parts of the medicine are such as
Shown in lower:
Chinese ephedra 100g, tuber of dwarf lilyturf 150g, bulbus fritillariae cirrhosae 120g, loguat leaf 160g, asparagus fern 150g, aster 100g, pappy shell 120g, the wind-weed
130g, radix scutellariae 100g, radix glycyrrhizae 150g, Exocarpium Citri Rubrum 100g, menthol 1.5g, root bark of white mulberry 150g, appropriate starch.
Model case
Through clinical conditions cough patients totally 1190, the age is 870 of more than 14 years old, and only 320 are less than 14 years old.
1030 to be fully recovered in 1190 patients, effective 160.Total effective rate is up to 100%.
Claims (3)
- A kind of 1. pill medicine that can effectively treat cough, it is characterised in that each component and its mass parts ratio of the medicine It is as follows:25~100g of Chinese ephedra, 60~150g of the tuber of dwarf lilyturf, 30~120g of bulbus fritillariae cirrhosae, 90~160g of loguat leaf, 60~150g of asparagus fern, aster 50~100g, 50~120g of pappy shell, 60~130g of the wind-weed, 30~100g of radix scutellariae, 30~150g of radix glycyrrhizae, 30~100g of Exocarpium Citri Rubrum, 0.5~1.5g of menthol, 60~150g of the root bark of white mulberry, appropriate starch.
- 2. the pill medicine according to claim 1 that can effectively treat cough, it is characterised in that each group of the medicine Divide and its mass parts are than as follows:28~90g of Chinese ephedra, 70~130g of the tuber of dwarf lilyturf, 38~105g of bulbus fritillariae cirrhosae, 100~140g of loguat leaf, 70~130g of asparagus fern, aster 60~90g, 60~105g of pappy shell, 60~115g of the wind-weed, 36~90g of radix scutellariae, 38~130g of radix glycyrrhizae, 36~90g of Exocarpium Citri Rubrum, peppermint 0.8~1.3g of brain, 70~130g of the root bark of white mulberry, appropriate starch.
- 3. the pill medicine that can effectively treat cough according to claim 1 to 2, it is characterised in that the medicine it is each Individual component and its mass parts are than as follows:Chinese ephedra 80g, tuber of dwarf lilyturf 115g, bulbus fritillariae cirrhosae 95g, loguat leaf 120g, asparagus fern 115g, aster 80g, pappy shell 95g, the wind-weed 100g, radix scutellariae 80g, radix glycyrrhizae 115g, Exocarpium Citri Rubrum 80g, menthol 1g, root bark of white mulberry 115g, appropriate starch.
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Application publication date: 20171124 |