CN107372521A - A kind of azoxystrobin microemulsion and preparation method thereof - Google Patents
A kind of azoxystrobin microemulsion and preparation method thereof Download PDFInfo
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- CN107372521A CN107372521A CN201710580576.3A CN201710580576A CN107372521A CN 107372521 A CN107372521 A CN 107372521A CN 201710580576 A CN201710580576 A CN 201710580576A CN 107372521 A CN107372521 A CN 107372521A
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- Prior art keywords
- fluoxastrobin
- microemulsion containing
- solvent
- deionized water
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
- A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Dentistry (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a kind of bactericidal microemulsion containing Fluoxastrobin, and containing Fluoxastrobin 5 30%, solvent 5 15%, emulsifying agent 10 25%, antifreezing agent 2 8%, remaining is deionized water, and the summation of raw material is 100%.Its preparation method is, first Fluoxastrobin is added in dissolving after heating for dissolving in a heated condition and is stirred, antifreezing agent and emulsifying agent are added during stirring, after above-mentioned material is well mixed, accelerate mixing speed, and deionized water is slowly added to, continue thereafter with maintenance and stir and material is heated to 50 70 DEG C, the bactericidal microemulsion containing Fluoxastrobin is can be prepared by room temperature is cooled to after homogeneous liquid.Method production is simple, storing safety, small to people, animal safety, effect on environment.
Description
Technical field
The present invention relates to a kind of bactericide, more particularly to a kind of bactericidal microemulsion and its system using Fluoxastrobin as active ingredient
Preparation Method.
Background technology
In fields such as agricultural, forestry, health, environmental protection, herdings, universal prevents and treats harmful organism using agricultural chemicals, or makes
The growth of crop is adjusted with growth regulator.For example, agriculturally for the Rogor of desinsection, phoxim etc., for rattling away for mite killing
Mite spirit, for the carbendazim sterilized, for the glyphosate of weeding, element etc. is strengthened for the post of regulating crop growth.In sanitary insect pest
The tetramethrin that is used in preventing and treating, Permethrin etc..In herding louse is prevented and treated with Amitraz.
The kind of these agricultural chemicals, it is water miscible to have some, is used after directly being mixed with water, such as glyphosate, hundred
Grass is withered etc., can directly be processed into aqua use；Most pesticide species are ester dissolubilities, such as phoxim, pyridaben, amine chrysanthemum
Ester, Permethrin etc., it is impossible to be processed into aqua use.Various formulations, such as missible oil, wettable powder, suspending agent are often processed into,
Used during use after dilutable water.
When missible oil is made in the farm chemical ingredients of ester dissolubility, usually solvent, active ingredient, surfactant are mixed, used
When, missible oil is diluted to white emulsion with water.Because missible oil forms particle diameter in water is more than 400nmO/W drops
The reason for.If formed oil/water size droplet diameter very little, when particle diameter is less than 100nm, it is seen that be exactly homogeneous transparent liquid,
Now, medicament forms microemulsion with water.In most cases, oil/water size droplet diameter is smaller, and drug effect plays better, so,
In general, under conditions of same dosage, the effect of microemulsion is better than missible oil.
The production method of usual microemulsion, is to be mixed using organic solvent with active ingredient, cosolvent, surfactant, water
Made from conjunction, especially when under pesticide active ingredient normal temperature being the material of solid, solvent and/or cosolvent are essential.
Fluoxastrobin, it is the methoxy acrylic bactericide for first commercialization that Syngenta Co., Ltd succeeds in developing, it is high
Effect, wide spectrum, to almost all of fungi steel (Ascomycetes, Basidiomycetes, Oomycete and Fungi Imperfecti) disease such as powdery mildew, rust
Disease, glume blight, net blotch, downy mildew, rice blast etc. have good activity.Available for cauline leaf spraying, seed treatment, can also enter
Row soil treatment, it is mainly used in cereal, rice, peanut, grape, potato, fruit tree, vegetables, coffee, lawn etc..Dosage
For 25-400g/hm 2, trade name Abound, Amistar, Heritage, Quadris, Admire.
Current market sales of preparation is mainly that 25% Fluoxastrobin suspending agent there are no the report for being processed into microemulsion
Road and patent.After Fluoxastrobin is processed into microemulsion, drug effect can be largely improved, reduces the usage amount of organic solvent
With the pollution to environment, so as to reduce residual of the Fluoxastrobin in agricultural product, agricultural product quality is improved.Therefore " efficiently, less toxic,
The azoxystrobin microemulsion of safety, economy " plays in agricultural product produce and stored especially high added value agricultural product production and processing
Important function.The successful development and application of azoxystrobin microemulsion will have great Social benefit and economic benefit.
The content of the invention
It is an object of the invention to provide a kind of bactericidal microemulsion containing Fluoxastrobin and preparation method thereof, this contains Fluoxastrobin
The Environmental compatibility of bactericidal microemulsion form is good, can embody the characteristics of Fluoxastrobin is efficient, less toxic completely.Realize foregoing invention mesh
Technical solution be：
A kind of bactericidal microemulsion containing Fluoxastrobin, it is characterised in that the microemulsion contains the raw material of following mass percent：
Fluoxastrobin 5-30%, solvent 5-15%, emulsifying agent 10-25%, antifreezing agent 2-8%, remaining is deionized water, and the summation of raw material is
100%.
Described emulsifying agent is selected from alkyl polyoxyethylene ether sulfonate, alkylphenol-polyethenoxy base ether formaldehyde condensation products, alkane
It is base phenol polyethenoxy base ether, Nonyl pheno base ether, polyoxyethylene polyoxypropylene base ether block copolymers, pull open powder, poly-
Second carboxylic acid ester sodium salt, alkylpolyoxyethylene phosphate, alkyl naphthalene formaldehyde condensate sulfonates, oleic acid methylaminoethyl
One or more in sodium sulfonate, alkyl acid polyoxyethylene groups ether sulfonate.
One or more of the described antifreezing agent in ethylene glycol, glycerine, propane diols, polyethylene glycol, urea.Described
One or more of the solvent in methanol, ethanol, dimethylbenzene, cyclohexanone, 1-METHYLPYRROLIDONE, dimethyl sulfoxide.
The preparation method of the above-mentioned bactericidal microemulsion containing Fluoxastrobin, it is characterised in that this method is accurate by proportioning by raw material first
Fluoxastrobin, is first added in solvent dissolves by heating in a heated condition, be stirred after Fluoxastrobin fully dissolves by standby raw material,
Antifreezing agent and emulsifying agent are added during stirring, after above-mentioned material is well mixed, accelerates mixing speed, and be slowly added to deionization
Water, continue thereafter with maintenance and stir and material is heated to 50-70 DEG C, can be made containing Fluoxastrobin in room temperature is cooled to after homogeneous liquid
Microemulsion.
The azoxystrobin microemulsion of the present invention is a kind of water baseization preparation, and the Environmental compatibility of its dosage form is good, is applied to
A variety of fungus-caused diseases are prevented and treated, production method is simple, storing safety, small to people, animal safety, effect on environment.
Embodiment
Embodiment 1-10% azoxystrobin microemulsions
10.6 kilograms of 95% Fluoxastrobin active compound is weighed, adds 6 kilograms of methanol, stirring, heating are completely dissolved it, stirred
2 kilograms of alkyl polyoxyethylene ether sulfonate of lower addition, 3 kilograms of alkylphenol-polyethenoxy base ether formaldehyde condensation products and 1.5 kilogram ten
Dialkyl benzene sulfonic acids sodium, it is well mixed, then keeps separately adding 2 kilograms of cyclohexanone and 4 kilograms of ethylene glycol under agitation, mixing is equal
Deionized water is added after even under high velocity agitation and is assigned to 100 kilograms；50 DEG C are heated to after well mixed, after in cold after homogeneous liquid
But to room temperature, 10% azoxystrobin microemulsion is produced.Embodiment 2-15% azoxystrobin microemulsions
15.8 kilograms of 95% Fluoxastrobin active compound is weighed, adds 10 kilograms of cyclohexanone, stirring, heating are completely dissolved it,
Stirring is lower to add 3 kilograms of Nonyl pheno base ether, 7 kilograms of alkylpolyoxyethylene phosphates and 5 kilograms of dodecyls
Benzene sulfonic acid sodium salt, it is well mixed, then keeps separately adding 4 kilograms of ethylene glycol under agitation, adds under high velocity agitation after being well mixed
Enter deionized water and be assigned to 100 kilograms；50 DEG C are heated to after well mixed, after in room temperature is cooled to after homogeneous liquid, produces 15%
Azoxystrobin microemulsion.
Embodiment 3-20% azoxystrobin microemulsions
21.2 kilograms of 95% Fluoxastrobin active compound is weighed, adds 14 kilograms of 1-METHYLPYRROLIDONEs, stirring, heating make its complete
Dissolve, under agitation 5 kilograms of poly- second carboxylic acid ester sodium salts of addition, 8 kilograms of alkylphenol-polyethenoxy base ether formaldehyde condensation products and 3 kilograms
Neopelex, it is well mixed, then keeps separately adding 4 kilograms of propane diols under agitation, at a high speed after is well mixed
The lower addition deionized water of stirring is assigned to 100 kilograms；60 DEG C are heated to after well mixed, room temperature is cooled to after being in homogeneous liquid,
Produce 20% azoxystrobin microemulsion.
Embodiment 4-25% azoxystrobin microemulsions
26.4 kilograms of 95% Fluoxastrobin active compound is weighed, adds 15 kilograms of cyclohexanone, stirring, heating are completely dissolved it,
Stirring is lower to add 7 kilograms of poly- second carboxylic acid ester sodium salts, 5 kilograms of alkylphenol-polyethenoxy base ether formaldehyde condensation products and 6 kilograms of oleic acid first
Base aminoethylsulfonic acid sodium, it is well mixed, then keeps separately adding 4 kilograms of propane diols under agitation, at a high speed after is well mixed
The lower addition deionized water of stirring is assigned to 100 kilograms；60 DEG C are heated to after well mixed, room temperature is cooled to after being in homogeneous liquid,
Produce 25% azoxystrobin microemulsion.
Claims (5)
- A kind of 1. bactericidal microemulsion containing Fluoxastrobin, it is characterised in that：The microemulsion contains the raw material of following mass percent：It is phonetic Bacterium ester 5-30%, solvent 5-15%, emulsifying agent 10-25%, antifreezing agent 2-8%, remaining is deionized water, and the summation of raw material is 100%.
- 2. the bactericidal microemulsion containing Fluoxastrobin as claimed in claim 1, it is characterised in that：Described emulsifying agent gathers selected from alkyl Oxygen ethene ether sulfonate, alkylphenol-polyethenoxy base ether formaldehyde condensation products, alkylphenol-polyethenoxy base ether, Nonyl pheno Base ether, polyoxyethylene polyoxypropylene base ether block copolymers, pull open powder, poly- second carboxylic acid ester sodium salt, alkylpolyoxyethylene Phosphate, alkyl naphthalene formaldehyde condensate sulfonates, oleic acid methylaminoethyl sodium sulfonate, alkyl acid polyoxyethylene groups ether sulfonic acid Salt.
- 3. the bactericidal microemulsion containing Fluoxastrobin as claimed in claim 1, it is characterised in that：Described antifreezing agent is selected from second two In alcohol, glycerine, propane diols, polyethylene glycol, urea.
- 4. the bactericidal microemulsion containing Fluoxastrobin as claimed in claim 1, it is characterised in that：Described solvent is selected from methanol, second In alcohol, dimethylbenzene, cyclohexanone, 1-METHYLPYRROLIDONE, dimethyl sulfoxide.
- A kind of 5. preparation method of the bactericidal microemulsion containing Fluoxastrobin as described in claim 1-4, it is characterised in that：According to Fluoxastrobin 5-30%, solvent 5-15%, emulsifying agent 10-25%, antifreezing agent 2-8%, remaining is deionized water, and the summation of raw material is 100% Ratio prepare raw material, first Fluoxastrobin is added in solvent dissolved by heating in a heated condition, after Fluoxastrobin fully dissolves Be stirred, antifreezing agent and emulsifying agent added during stirring, after above-mentioned material is well mixed, accelerate mixing speed, and slowly plus Enter deionized water, continue thereafter with maintenance and stir and material is heated to 50-70 DEG C, can be made in room temperature is cooled to after homogeneous liquid Microemulsion containing Fluoxastrobin.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710580576.3A CN107372521A (en) | 2017-07-17 | 2017-07-17 | A kind of azoxystrobin microemulsion and preparation method thereof |
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| CN201710580576.3A CN107372521A (en) | 2017-07-17 | 2017-07-17 | A kind of azoxystrobin microemulsion and preparation method thereof |
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| CN107372521A true CN107372521A (en) | 2017-11-24 |
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| CN201710580576.3A Pending CN107372521A (en) | 2017-07-17 | 2017-07-17 | A kind of azoxystrobin microemulsion and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113383771A (en) * | 2021-06-29 | 2021-09-14 | 安徽广信农化股份有限公司 | Pyraclostrobin microemulsion and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101443012B (en) * | 2006-03-31 | 2011-11-09 | 先正达参股股份有限公司 | Azoxystrobin formulations |
| CN103598188A (en) * | 2013-08-21 | 2014-02-26 | 陕西康禾立丰生物科技药业有限公司 | Azoxystrobin-containing pesticide composition |
| CN106879583A (en) * | 2017-04-24 | 2017-06-23 | 孙淑珍 | A kind of Fluoxastrobin and chlorothalonil compound microemulsion and preparation method thereof |
-
2017
- 2017-07-17 CN CN201710580576.3A patent/CN107372521A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101443012B (en) * | 2006-03-31 | 2011-11-09 | 先正达参股股份有限公司 | Azoxystrobin formulations |
| CN103598188A (en) * | 2013-08-21 | 2014-02-26 | 陕西康禾立丰生物科技药业有限公司 | Azoxystrobin-containing pesticide composition |
| CN106879583A (en) * | 2017-04-24 | 2017-06-23 | 孙淑珍 | A kind of Fluoxastrobin and chlorothalonil compound microemulsion and preparation method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113383771A (en) * | 2021-06-29 | 2021-09-14 | 安徽广信农化股份有限公司 | Pyraclostrobin microemulsion and preparation method thereof |
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Application publication date: 20171124 |
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