CN107365485A - A kind of medical grade rubber bottle stopper and preparation method thereof - Google Patents
A kind of medical grade rubber bottle stopper and preparation method thereof Download PDFInfo
- Publication number
- CN107365485A CN107365485A CN201710853458.5A CN201710853458A CN107365485A CN 107365485 A CN107365485 A CN 107365485A CN 201710853458 A CN201710853458 A CN 201710853458A CN 107365485 A CN107365485 A CN 107365485A
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- China
- Prior art keywords
- parts
- rubber
- bottle stopper
- medical grade
- medical
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Classifications
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L67/00—Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
- C08L67/02—Polyesters derived from dicarboxylic acids and dihydroxy compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K3/00—Use of inorganic substances as compounding ingredients
- C08K3/18—Oxygen-containing compounds, e.g. metal carbonyls
- C08K3/24—Acids; Salts thereof
- C08K3/26—Carbonates; Bicarbonates
- C08K2003/265—Calcium, strontium or barium carbonate
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2203/00—Applications
- C08L2203/10—Applications used for bottles
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2205/00—Polymer mixtures characterised by other features
- C08L2205/03—Polymer mixtures characterised by other features containing three or more polymers in a blend
- C08L2205/035—Polymer mixtures characterised by other features containing three or more polymers in a blend containing four or more polymers in a blend
Abstract
The invention discloses a kind of medical grade rubber bottle stopper and preparation method thereof, according to the number of parts by weight, includes the raw material of following number：50 70 parts of PET resin, 20 40 parts of fluorosioloxane rubber, 5 15 parts of oyster shell whiting, 5 15 parts of rare-earth coupling agent (DN 8102), 0.8 1.5 parts of stannous oxide, 0.3 0.7 parts of medical ventolin, 60 72 parts of diatomite, 0.1 0.3 parts of five diamines of tetravinyl, 37 parts of hydroxy silicon oil, age resistor dredge 0.6 1.5 parts of base benzimidazole, 0.2 0.5 parts of 2-pyrrolidone-5-carboxylic acid's potassium, 0.1 0.3 parts of di-t-butyl peroxide, 12 parts of Sulfur.Bottle stopper provided by the invention has excellent ageing-resistant, cracking resistance, bacteriostasis property, and its elongation at break is big, is a kind of preferably medical grade rubber bottle stopper.
Description
Technical field
The invention belongs to technical field of rubber material, more particularly to a kind of medical grade rubber bottle stopper and preparation method thereof.
Background technology
Rubber is widely used in all aspects of industry or life.There are many rubbers answering in medical department
With the diagnosis of department of anesthesia, urological department, surgery, cranial surgery, orthopaedics, five palace sections, dept. of radiology's trick in such as hospital, transfusing blood, lead
Mostly urine, the gloves of various glue color operations of intestinal lavage stomach, ice capsule, sponge seat cushion etc. are rubbers.As Medical Devices and instrument
The accessory of device also has rubber.Druggist rubber sundrier often also has particular/special requirement to it, such as nontoxic, sterilization, physiological inertia,
Resistance to radiation etc..
Medical grade rubber bottle stopper is the heat-resistant powder filler product for having definite shape, size, medicinal for glass, plastics etc.
The sealing of flask mouth.Its structure is broadly divided into taper, T-shaped and the class of flange shape three；By purposes can be divided into Content Within Pharmaceutical Closure,
Biologics bottle stopper, spraying medicament bottle stopper and transfusion bottle stopper etc..Bottle stopper sizing material requires that not leaded, mercury, arsenic, barium etc. are harmful solvable
Thing, with can powder charge agent do not work, bottle stopper can not have ejecta in itself.It is general to use the sizing materials such as NR, IIR and SBR to make, with molding
Method produces, and is widely used in pharmacy and medical industry.
Existing medical grade rubber bottle stopper flavescence easy to aging in the market, cracking resistance difference is easy to crack, fungistatic effect is poor, and
And its elongation at break is limited, these all serve restriction effect to the use of bottle closure of rubber.
The content of the invention
It is an object of the invention to provide a kind of medical grade rubber bottle stopper and preparation method thereof.
The purpose of the present invention can be achieved through the following technical solutions：
A kind of medical grade rubber bottle stopper, according to the number of parts by weight, include the raw material of following number：PET resin 50-70 parts,
Fluorosioloxane rubber 20-40 parts, oyster shell whiting 5-15 parts, rare-earth coupling agent (DN-8102) 5-15 parts, stannous oxide 0.8-1.5 parts are medical
Vaseline 0.3-0.7 parts, diatomite 60-72 parts, the diamines 0.1-0.3 parts of tetravinyl five, hydroxy silicon oil 3-7 parts, age resistor are dredged
Base benzimidazole 0.6-1.5 parts, 2-pyrrolidone-5-carboxylic acid's potassium 0.2-0.5 parts, di-t-butyl peroxide 0.1-0.3 parts, Sulfur 1-2
Part.
A kind of described medical grade rubber bottle stopper, according to the number of parts by weight, includes the raw material of following number：PET resin 65
Part, 30 parts of fluorosioloxane rubber, 10 parts of oyster shell whiting, 10 parts of rare-earth coupling agent (DN-8102), 1 part of stannous oxide, medical ventolin 0.4
Part, 65 parts of diatomite, 0.3 part of five diamines of tetravinyl, 4 parts of hydroxy silicon oil, thin 1 part of the base benzimidazole of age resistor, pyrrolidones
0.3 part of carboxylic acid potassium, 0.3 part of di-t-butyl peroxide, 2 parts of Sulfur.
A kind of described medical grade rubber bottle stopper, its preparation method comprise the following steps：
(1) each raw material components are weighed according to ratio of weight and number；
(2) PET resin, fluorosioloxane rubber, the diamines of tetravinyl five, rare-earth coupling agent (DN-8102) are added in rubber mixing machine
It is kneaded；
(3) oyster shell whiting, stannous oxide, medical ventolin, diatomite, hydroxyl silicon are added in the rubber mixing machine into step (2)
Oil, 2-pyrrolidone-5-carboxylic acid's potassium, Sulfur, after being well mixed, 80-86 minutes are kneaded, obtain mixing virgin rubber；
(4) age resistor is added in the mixing virgin rubber into step (3) and dredges base benzimidazole, di-t-butyl peroxide, is kneaded
15-18 minutes, that is, obtain the rubber composite.
Beneficial effects of the present invention：Bottle stopper provided by the invention has excellent ageing-resistant, cracking resistance, bacteriostasis property, and
Its elongation at break is big, is a kind of preferably medical grade rubber bottle stopper.
Embodiment
The present invention is described in further detail with reference to specific embodiment.
Embodiment 1
A kind of medical grade rubber bottle stopper, according to the number of parts by weight, include the raw material of following number：50 parts of PET resin, fluorine silicon
20 parts of rubber, 5 parts of oyster shell whiting, 5 parts of rare-earth coupling agent (DN-8102), 0.8 part of stannous oxide, 0.3 part of medical ventolin, diatom
60 parts of soil, 0.1 part of five diamines of tetravinyl, 3 parts of hydroxy silicon oil, age resistor dredge 0.6 part of base benzimidazole, 2-pyrrolidone-5-carboxylic acid's potassium
0.2 part, 0.1 part of di-t-butyl peroxide, 1 part of Sulfur.
Its preparation method comprises the following steps：
(1) each raw material components are weighed according to ratio of weight and number；
(2) PET resin, fluorosioloxane rubber, the diamines of tetravinyl five, rare-earth coupling agent (DN-8102) are added in rubber mixing machine
It is kneaded；
(3) oyster shell whiting, stannous oxide, medical ventolin, diatomite, hydroxyl silicon are added in the rubber mixing machine into step (2)
Oil, 2-pyrrolidone-5-carboxylic acid's potassium, Sulfur, after being well mixed, 80-86 minutes are kneaded, obtain mixing virgin rubber；
(4) age resistor is added in the mixing virgin rubber into step (3) and dredges base benzimidazole, di-t-butyl peroxide, is kneaded
15-18 minutes, that is, obtain the rubber composite.
Embodiment 2
A kind of medical grade rubber bottle stopper and preparation method thereof, according to the number of parts by weight, include the raw material of following number：PET
70 parts of resin, 40 parts of fluorosioloxane rubber, 15 parts of oyster shell whiting, 15 parts of rare-earth coupling agent (DN-8102), 1.5 parts of stannous oxide are medical all
0.7 part of intellectual circle, 72 parts of diatomite, 0.3 part of five diamines of tetravinyl, hydroxy silicon oil part, age resistor dredge 1.5 parts of base benzimidazole,
0.5 part of 2-pyrrolidone-5-carboxylic acid's potassium, 0.3 part of di-t-butyl peroxide, 2 parts of Sulfur.
Its preparation method comprises the following steps：
(1) each raw material components are weighed according to ratio of weight and number；
(2) PET resin, fluorosioloxane rubber, the diamines of tetravinyl five, rare-earth coupling agent (DN-8102) are added in rubber mixing machine
It is kneaded；
(3) oyster shell whiting, stannous oxide, medical ventolin, diatomite, hydroxyl silicon are added in the rubber mixing machine into step (2)
Oil, 2-pyrrolidone-5-carboxylic acid's potassium, Sulfur, after being well mixed, 80-86 minutes are kneaded, obtain mixing virgin rubber；
(4) age resistor is added in the mixing virgin rubber into step (3) and dredges base benzimidazole, di-t-butyl peroxide, is kneaded
15-18 minutes, that is, obtain the rubber composite.
Embodiment 3
A kind of medical grade rubber bottle stopper and preparation method thereof, according to the number of parts by weight, include the raw material of following number：PET
65 parts of resin, 30 parts of fluorosioloxane rubber, 10 parts of oyster shell whiting, 10 parts of rare-earth coupling agent (DN-8102), 1 part of stannous oxide, medical all scholars
0.4 part of woods, 65 parts of diatomite, 0.3 part of five diamines of tetravinyl, 4 parts of hydroxy silicon oil, age resistor dredge 1 part of base benzimidazole, pyrroles
0.3 part of alkanone carboxylic acid potassium, 0.3 part of di-t-butyl peroxide, 2 parts of Sulfur.
Its preparation method comprises the following steps：
(1) each raw material components are weighed according to ratio of weight and number；
(2) PET resin, fluorosioloxane rubber, the diamines of tetravinyl five, rare-earth coupling agent (DN-8102) are added in rubber mixing machine
It is kneaded；
(3) oyster shell whiting, stannous oxide, medical ventolin, diatomite, hydroxyl silicon are added in the rubber mixing machine into step (2)
Oil, 2-pyrrolidone-5-carboxylic acid's potassium, Sulfur, after being well mixed, 80-86 minutes are kneaded, obtain mixing virgin rubber；
(4) age resistor is added in the mixing virgin rubber into step (3) and dredges base benzimidazole, di-t-butyl peroxide, is kneaded
15-18 minutes, that is, obtain the rubber composite.
Above content is only to design example and explanation of the invention, affiliated those skilled in the art
Various modifications or supplement are made to described specific embodiment or is substituted using similar mode, without departing from invention
Design or surmount scope defined in the claims, protection scope of the present invention all should be belonged to.
Claims (3)
1. a kind of medical grade rubber bottle stopper, it is characterised in that according to the number of parts by weight, include the raw material of following number：PET resin
50-70 parts, fluorosioloxane rubber 20-40 parts, oyster shell whiting 5-15 parts, rare-earth coupling agent (DN-8102) 5-15 parts, stannous oxide 0.8-
1.5 parts, medical ventolin 0.3-0.7 parts, diatomite 60-72 parts, the diamines 0.1-0.3 parts of tetravinyl five, hydroxy silicon oil 3-7
Part, age resistor dredges base benzimidazole 0.6-1.5 parts, 2-pyrrolidone-5-carboxylic acid's potassium 0.2-0.5 parts, di-t-butyl peroxide 0.1-0.3
Part, Sulfur 1-2 parts.
A kind of 2. medical grade rubber bottle stopper according to claim 1, it is characterised in that according to the number of parts by weight, including with
The raw material of lower number：65 parts of PET resin, 30 parts of fluorosioloxane rubber, 10 parts of oyster shell whiting, 10 parts of rare-earth coupling agent (DN-8102), oxidation
1 part of stannous, 0.4 part of medical ventolin, 65 parts of diatomite, 0.3 part of five diamines of tetravinyl, 4 parts of hydroxy silicon oil, age resistor dredges base
1 part of benzimidazole, 0.3 part of 2-pyrrolidone-5-carboxylic acid's potassium, 0.3 part of di-t-butyl peroxide, 2 parts of Sulfur.
3. a kind of medical grade rubber bottle stopper according to claim 1, it is characterised in that its preparation method comprises the following steps：
(1) each raw material components are weighed according to ratio of weight and number；
(2) PET resin, fluorosioloxane rubber, the diamines of tetravinyl five, rare-earth coupling agent (DN-8102) are added in rubber mixing machine and carried out
It is kneaded；
(3) oyster shell whiting, stannous oxide, medical ventolin, diatomite, hydroxy silicon oil, pyrrole are added in the rubber mixing machine into step (2)
Pyrrolidone carboxylic acid's potassium, Sulfur, after being well mixed, 80-86 minutes are kneaded, obtain mixing virgin rubber；
(4) age resistor is added in the mixing virgin rubber into step (3) and dredges base benzimidazole, di-t-butyl peroxide, is kneaded 15-18
Minute, that is, obtain the rubber composite.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710853458.5A CN107365485A (en) | 2017-09-20 | 2017-09-20 | A kind of medical grade rubber bottle stopper and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710853458.5A CN107365485A (en) | 2017-09-20 | 2017-09-20 | A kind of medical grade rubber bottle stopper and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107365485A true CN107365485A (en) | 2017-11-21 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710853458.5A Pending CN107365485A (en) | 2017-09-20 | 2017-09-20 | A kind of medical grade rubber bottle stopper and preparation method thereof |
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| Country | Link |
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| CN (1) | CN107365485A (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104448731A (en) * | 2014-11-27 | 2015-03-25 | 苏州市贝克生物科技有限公司 | Anti-aging composite material for medical cock and preparation method of anti-aging composite material |
-
2017
- 2017-09-20 CN CN201710853458.5A patent/CN107365485A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104448731A (en) * | 2014-11-27 | 2015-03-25 | 苏州市贝克生物科技有限公司 | Anti-aging composite material for medical cock and preparation method of anti-aging composite material |
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Application publication date: 20171121 |
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