CN107362464A - Accurate Stereotactic Radiosurgery device - Google Patents
Accurate Stereotactic Radiosurgery device Download PDFInfo
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- CN107362464A CN107362464A CN201710688854.7A CN201710688854A CN107362464A CN 107362464 A CN107362464 A CN 107362464A CN 201710688854 A CN201710688854 A CN 201710688854A CN 107362464 A CN107362464 A CN 107362464A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/103—Treatment planning systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1042—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy with spatial modulation of the radiation beam within the treatment head
- A61N5/1045—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy with spatial modulation of the radiation beam within the treatment head using a multi-leaf collimator, e.g. for intensity modulated radiation therapy or IMRT
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
- A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
- A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
- A61N2005/1054—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam using a portal imaging system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
- A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
- A61N2005/1055—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam using magnetic resonance imaging [MRI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
- A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
- A61N2005/1058—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam using ultrasound imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
- A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
- A61N2005/1061—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam using an x-ray imaging system having a separate imaging source
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N2005/1092—Details
Abstract
The invention belongs to a kind of precisely Stereotactic Radiosurgery device in field of medical device, it is made up of radiation appliance system, sextuple robot therapeutic bed 1 and treatment planning systems；Radiation appliance system is made up of frame 12 and C-shaped horn 5, and rotating shaft 10 is provided with frame 12, and rotating shaft 10 is connected with guide rail 9 and controls the rotation of guide rail 9, and C-shaped horn 5 is installed on the rail 9 and carries out arcuate movement along guide rail 9；The one end of C-shaped horn 5 is provided with radiographic source 2, and the bottom of radiographic source 2 is provided with small handpiece 3, and the bottom of small handpiece 3 is provided with collimater 4；The other end of C-shaped horn 5 is provided with scalable electronic portal image device 7 and portable shielding protection balancing weight 8；Target organ positioning detection device 6 is arranged on the sextuple bed surface side of robot therapeutic bed 1 or lower section.Present apparatus radiation therapy head can make 90 degree of (or ± 45 degree) rotary motions around X-axis so that radial energy is launched on a non-coplanar track of 4 π.
Description
Technical field
The invention belongs to field of medical device, and in particular to a kind of precisely Stereotactic Radiosurgery device.
Background technology
Stereotaxis Interesting Issues of Precise Radiation is using multi-beam, non-co-planar, high dose rate, small wild irradiation, in neoplastic disease
Stove center Jin Hang Ji Bouquet are focused on, and are adjusted by beam intensity so that dosage is distributed in fast in the range of target volume edge submillimeter level
Quick depletion, the damage to normal surrounding tissue is reduced, expanded the adaptability of radiotherapy, be obviously improved patient's curative effect.
But the implementation of this technology proposes higher requirement to therapeutic equipment precision, plan precision, pendulum position precision, treatment precision.
The existing stereo directional radiotherapy apparatus using accelerator as radiation source is vertical with frame rotary shaft Y and therapeutic bed rotary shaft Z
Intersect form rotary motion system, the accelerator treatment head big frames of Zhi Neng Sui around Y-axis make 360 degree of rotary motions with around parallel
In the small handpiece axle rotation of Z axis.Typically frame surrounds is rotated by the Y-axis in isocentric rifle-target direction, and therapeutic bed is then
Rotated around by isocentric rotating disk Z axis, radiation therapy head is being that W directions can not move to Z axis incline direction, and radiation source is penetrated
Beam is extremely restricted in the non-co-planar space illumination scopes of 4 π.
The content of the invention
The invention aims to overcome existing accelerator stereo directional radiotherapy apparatus radiation therapy head Zhi Neng Sui
Big frame is around Y-axis Xuan Zhuan He Sui small handpieces are extremely restricted not parallel to Z axis rotation, radiation source beam spatial range of exposures
Foot, there is provided a kind of radiation therapy head Chu the big frames of Ke Yi Sui around Y-axis Xuan Zhuan He in addition to Sui small handpieces are parallel to Z axis rotation, may be used also
To make 90 degree of (or ± 45 degree) rotary motions around X-axis so that radial energy is launched accurate on the non-co-planar space trackings of 4 π
Stereotactic Radiosurgery device.
The purpose of the present invention is realized by following technical proposals：
The accurate Stereotactic Radiosurgery device of the present invention, mainly by radiation appliance system, sextuple robot therapeutic bed 1
Formed with treatment planning systems；It is characterized in that the radiation appliance system is made up of frame 12 and C-shaped horn 5, in frame 12
Rotating shaft 10 is provided with, rotating shaft 10 is connected with guide rail 9 and controls the rotation of guide rail 9, and C-shaped horn 5 is installed on the rail 9 and along guide rail
9 carry out arcuate movement；The one end of C-shaped horn 5 is provided with radiographic source 2, and the bottom of radiographic source 2 is provided with small handpiece 3, the bottom of small handpiece 3
Collimater 4 is installed；The other end of C-shaped horn 5 is provided with scalable electronic portal image device（EPID）7 and portable shielding protection
Balancing weight 8；Target organ positioning detection device 6 is arranged on the sextuple bed surface side of robot therapeutic bed 1 or lower section.
In such scheme, radiographic source auxiliary member 11 is provided with the frame 12.
In such scheme, the accelerating tube of the radiographic source 2 is C-band accelerating tube or X-band；The collimater 4 is circle
Collimater or multi-diaphragm collimator（MLC）.
In such scheme, the target organ positioning detection device 6 is X-ray image tracking, guiding, positioner or non-x-ray
Image trace, guiding, positioner.
In such scheme, the non-X-ray image tracking, guiding, positioner are that three-dimensional electrolysis cuts open Mapping System and three-dimensional
The emerging system and magnetic navigation automatic station-keeping system of intracardiac echocardiography.
In such scheme, the treatment planning systems are heart radiosurgery planning system or/and oncotherapy meter
The system of drawing.
In such scheme, its step of the heart radiosurgery planning system is：
The noninvasive acquisition of arrhythmia signal and positioning；By the bioelectrical activity of endocardial three dimensions, reverse calculate determines
The focus target area source position of arrhythmia cordis occurs；
Fixed point radiation ablation is carried out to the cardiac muscular tissue at source position；
The parameter of monitoring fixed point radiation ablation point in real time, the physical parameter and heart tissue ginseng of the collection beam X-ray correlation transmitted
Number, and guided according to the parameter of feedback, the transmission of boundling x-ray dose is adjusted or optimizes, to cause arrhythmia cordis
Treat more precise and high efficiency；
Arrhythmia cordis evaluation system is provided；Excite heart to produce electric signal by non-invasive manner, pinpointed with assisting in
Heart is directed at the originated location of arrhythmia cordis with the presence or absence of abnormal electricity physiological signal activity, or evaluation before radiation ablation
The fixed point radiation ablation made of cardiac muscular tissue whether really effectively.
In such scheme, the noninvasive acquisition of the arrhythmia signal and positioning step, it is specially：
Mapping System is cutd open using three-dimensional electrolysis（Such as：Carto systems）With three-dimensional intracardiac echocardiography（ICE）Fusion
（CartoSound）Method gathers electricity physiological signal processing system and 4D cardiac ultrasonics imaging side using body surface multiple spot is noninvasive
Method.
In such scheme, it is described use the fusion method that three-dimensional electrolysis cuts open Mapping System and three-dimensional intracardiac echocardiography for：
Three-dimensional intracardiac echocardiography in Mapping System will be cutd open by three-dimensional electrolysis（ICE）Probe is placed in the right room side of heart atrial septum,
Around its major axis rotating detector, the fault structure of the heart difference covering of the fan obtained, automatic identification, or artificial crisperding are carried out, is relied on
Related software, reconstruct the stereo profile of the chambers of the heart.
It is described using the noninvasive collection electricity physiological signal processing system of body surface multiple spot and the imaging of 4D cardiac ultrasonics in such scheme
Method is：
The body surface bioelectrical activity signal detected by the electrode being put at sites is obtained, is obtained by reverse computational methods
The bioelectrical activity of endocardial three dimensions, determine the generation position of arrhythmia cordis；
Determining device frame, sextuple robot therapeutic bed, collect beam X-ray relevant physical parameter and implement radiation ablation it is optimal
Path；
The cardiac image that will be obtained by 4D supersonic imaging devices, by multi-modality images fusion processing system, patient is coordinated
Some CT, CB CT, PET/CT, MRI, US image, image reconstruction is carried out, constructs the three of the three-dimensional heart and trunk of patient
Tie up anatomical model and VR scenes.
In such scheme, the oncotherapy planning system is divided into lower part：
Speed meets the high-precision dose calculation methodology (including monte carlo method) of clinical requirement；
Automatic profile based on artificial intelligence is delineated；
Quick plan based on big data experience；
Non-co-planar more wild focus on of 4 π plan reverse engineer system；
4D adaptive plannings.
The present invention the accurate Stereotactic Radiosurgery device course of work be：
Rotating shaft drives guide rail and C-shaped horn and radiographic source is surrounded by 360 degree of the Y-axis work in isocentric direction (or ± 190
Degree) rotary motion, small handpiece drive radiographic source and collimater are surrounded and rotated by 360 degree of work of isocentric Z axis (or ± 190 degree)
Motion, C-shaped horn drive radiographic source to make 90 degree of (or ± 45 degree) rotary motions around X-axis along guide rail, and composition is mutually perpendicular to the rotation of two axles
Transfer from one department to another to unite, corresponding to inclined certain angle ɑ of C-arm, frame rotates some angle φ, the radioactive ray of linear accelerator radiation head
Beam will scan out the circular cone covering of the fan for focusing on isocenter point so that radial energy is launched on the track of a taper.Sextuple machine
People's therapeutic bed can realize self-oscillate position, positioning, can carry out X, Y, the movement of Z-direction and rotation about the z axis, tilt and reverse,
Can be high-precision（Repetitive positioning accuracy is ± 0.2mm）Six-freedom motion, operate steadily, reliably, extremely flexibly coordinate radiographic source
The non-co-planar noninvasive radiosurgery irradiation treatments of 4 π to various different focus target areas are completed, make solid angle of patient's focus 100%
In the range of can obtain accurate irradiation, substantially increase 4 π it is non-co-planar treatment etc. center precision.
Conventional radiotheraphy medical computerized linear accelerator and common X- knife systems, the horizontal Y in its frame only wire-wrap tool-target direction
Axle rotates, and the mechanical balance counterweight problem of frame is easier to solve.The accurate Stereotactic Radiosurgery device of the present invention removes
Rotating shaft drives guide rail and C-shaped horn and radiographic source to make φ to outside rotation around Y-axis in frame, the C-shaped horn in frame upper rail
Also to make the rotation of ɑ angles around X axis direction.This just makes its mechanical balance counterweight thickening of problem, and existing φ is to rotation
Unbalance have unbalances of the ɑ to rotation again.The present invention uses can in one end setting relative with radiographic source of C-shaped horn
Telescopic movable shielding protection balancing weight solves the dynamic balancing during motion of C-shaped horn, while also solves shielding protection problem, can
Reduce the shielding requirements to computer room.
The accurate Stereotactic Radiosurgery device of the present invention also has following characteristics：
1. boundling beam dosage (adjusting X-band/C-band accelerator close rate) can be changed.
2. flexibly changing launched field distribution size (changing circular collimator aperture size or MLC Ziyes).
3. the π solid incident angles of boundling beam spatial 4 can be changed.
4. boundling beam plane of incidence can be changed (how non-co-planar robot bed arbitrarily arrangement is unlimited).
5. can change the centers such as boundling beam, noninvasive surgical operation Mutiple Targets disappear with mobile particularly outside ambition
It is more obvious to melt advantage in treatment.
6. substantially reducing treatment time, precision is improved, protects normal structure, improves therapeutic effect.
Therefore, accurate Stereotactic Radiosurgery device of the invention is by adjusting the dose intensity of boundling ray,
Using multiple high dose beam exposures, and by the width (on 4 π are non-co-planar) of size of tumor rightly superset beam line,
High dose area can be made to concentrate on different depth and different size of lesions position, while focus dosage is improved, substantially reduced
The exposure dose of normal structure, focus Partial controll rate can be improved and reduce Normal Tissue Complication；When single collection bunch is got over
It is more, focus target dose peak is more sharp, dosage is higher, passes through the big frame of radiation source head rotating and sextuple robot therapeutic bed
Harmonious motion, and combine the multi-modality images gathered in preoperative and art, real-time 4D motion management and control artificial intelligence (AI) etc.
Technology, brand-new noncoplanar irradiation technology is realized, it can allow wire harness stream, and almost any direction is incident in 4 π solid spaces, more
Filling is irradiated under conditions of protecting patient's normal structure organ again.
In summary, instant invention overcomes existing accelerator stereo directional radiotherapy apparatus radiation therapy head Zhi Neng Sui are big
Frame is around Y-axis Xuan Zhuan He Sui small handpieces are extremely restricted not parallel to Z axis rotation, radiation source beam spatial range of exposures
Foot, there is provided accurate Stereotactic Radiosurgery device radiation therapy head Chu Ke Yi Sui big frames around Y-axis Xuan Zhuan He Sui
Small handpiece parallel to Z axis rotation outside, can also around X-axis make 90 degree of (or ± 45 degree) rotary motions so that radial energy is in 4 π
Launch on non-coplanar track.
Brief description of the drawings：
Fig. 1 is the structural representation of the present invention.
Fig. 2 is the three-dimensional bundle irradiates schematic diagram of the present invention.
In accompanying drawing, each digital implication is：1：Sextuple robot therapeutic bed；2：Radiographic source；3：Small handpiece；4：Collimater；
5：C-shaped horn；6：Target organ positioning detection device；7：Scalable electronic portal image device；8：Portable shielding protects balancing weight；
9：Guide rail；10：Rotating shaft；11：Radiographic source auxiliary member；12：Frame.
Embodiment：
Below in conjunction with the accompanying drawings and the present invention is described in further detail in embodiment, but the present invention is not limited only to the embodiment.
Embodiment one
The accurate Stereotactic Radiosurgery device of this example, as depicted in figs. 1 and 2, for heart disease (such as atrial fibrillation, fertilizer
Thicker cardiomyopathy etc.) or surgical treatment, by radiation appliance system, sextuple robot therapeutic bed 1 and treatment planning systems group
Into；The radiation appliance system is made up of frame 12 and C-shaped horn 5, and rotating shaft 10, rotating shaft 10 and guide rail 9 are provided with frame 12
Connect and control the rotation of guide rail 9, C-shaped horn 5 is installed on the rail 9 and carries out arcuate movement along guide rail 9；The one end of C-shaped horn 5
Radiographic source 2 is installed, the bottom of radiographic source 2 is provided with small handpiece 3, and the bottom of small handpiece 3 is provided with collimater 4；C-shaped horn 5 is another
End is provided with scalable electronic portal image device（EPID）7 and portable shielding protection balancing weight 8；Target organ positioning detection device
6 are arranged on the sextuple bed surface side of robot therapeutic bed 1 or lower section.
Radiographic source auxiliary member 11 is provided with frame 12.
Radiographic source 2 is 6MV C-band accelerating tubes, and collimater 4 is circular collimater.
Target organ positioning detection device 6 is the tracking of non-X-ray image, guiding, positioner.
The tracking of non-X-ray image, guiding, positioner are that three-dimensional electrolysis cuts open merging for Mapping System and three-dimensional intracardiac echocardiography
System and magnetic navigation automatic station-keeping system.
Treatment planning systems are heart radiosurgery planning system.
Its step of heart radiosurgery planning system is：
The noninvasive acquisition of arrhythmia signal and positioning；By the bioelectrical activity of endocardial three dimensions, reverse calculate determines
The focus target area source position of arrhythmia cordis occurs；
Fixed point radiation ablation is carried out to the cardiac muscular tissue at source position；
The parameter of monitoring fixed point radiation ablation point in real time, the physical parameter and heart tissue ginseng of the collection beam X-ray correlation transmitted
Number, and guided according to the parameter of feedback, the transmission of boundling x-ray dose is adjusted or optimizes, to cause arrhythmia cordis
Treat more precise and high efficiency；
Arrhythmia cordis evaluation system is provided；Excite heart to produce electric signal by non-invasive manner, pinpointed with assisting in
Heart is directed at the originated location of arrhythmia cordis with the presence or absence of abnormal electricity physiological signal activity, or evaluation before radiation ablation
The fixed point radiation ablation made of cardiac muscular tissue whether really effectively.
The noninvasive acquisition of arrhythmia signal and positioning step, it is specially：
Mapping System is cutd open using three-dimensional electrolysis（Such as：Carto systems）With three-dimensional intracardiac echocardiography（ICE）Fusion
（CartoSound）Method gathers electricity physiological signal processing system and 4D cardiac ultrasonics imaging side using body surface multiple spot is noninvasive
Method.
Use three-dimensional electrolysis cut open the fusion method of Mapping System and three-dimensional intracardiac echocardiography for：
Three-dimensional intracardiac echocardiography in Mapping System will be cutd open by three-dimensional electrolysis（ICE）Probe is placed in the right room side of heart atrial septum,
Around its major axis rotating detector, the fault structure of the heart difference covering of the fan obtained, automatic identification, or artificial crisperding are carried out, is relied on
Related software, reconstruct the stereo profile of the chambers of the heart.
Use body surface multiple spot it is noninvasive collection electricity physiological signal processing system and 4D cardiac ultrasonics imaging method for：
The body surface bioelectrical activity signal detected by the electrode being put at sites is obtained, is obtained by reverse computational methods
The bioelectrical activity of endocardial three dimensions, determine the generation position of arrhythmia cordis；
Determining device frame, sextuple robot therapeutic bed, collect beam X-ray relevant physical parameter and implement radiation ablation it is optimal
Path；
The cardiac image that will be obtained by 4D supersonic imaging devices, by multi-modality images fusion processing system, patient is coordinated
Some CT, CB CT, PET/CT, MRI, US image, image reconstruction is carried out, constructs the three of the three-dimensional heart and trunk of patient
Tie up anatomical model and VR scenes.
The accurate Stereotactic Radiosurgery device of this example is simulated equipped with intelligent simulation and safety system.
For the accurate Stereotactic Radiosurgery device of this example using non-X-ray image from motion tracking, Virtual intends reality emulation
（VR）With self-navigation location technology, i.e. three-dimensional electrolysis cuts open Mapping System and three-dimensional intracardiac echocardiography emerging system, coordinate CT and
MRI four-dimensional image integration technologies, the position for causing tachycardic anomaly sxtructure is determined in inspection, or based on body surface ecg
The source information of cardiac electrical activity is obtained, it is precisely fixed using the reverse computational methods of the electrocardio of VR technologies and Electrocardial Heart Model parametric solution
Position abnormal potential focus target area, coordinates six-DOF robot high accuracy flexible positioning system, accurate collimater from hundreds of
The superfine beam line that the π stereo omnibearings of space 4 give off, very high dose of radiation is produced within the scope of the determination of very little, is collected at
Focus target area.Due to the biological effects of radiation, make heart local organization fibrosis downright bad, reach therapeutic purposes.Because ray is to the heart
Flesh locally causes damage to limit to very much, controllable in about millimetre-sized diameter range and depth, does not interfere with surrounding normal cardiac muscle group
Knit.Do not operate on, do not anaesthetize, therefore typically without significant discomfort in patient's art.Therapeutic process about or so half an hour completes, attention 1 to 2
It can leave hospital.Entirely different using radioscopic image positioner with external CyberHeart systems, the damage to patient is more
It is small, safety and reliability and precisely.Low in treatment cost, it can be used in conditional basic hospital large-scale popularization.
Embodiment two
The accurate Stereotactic Radiosurgery device of this example, for treating tumour, except radiographic source 2 is the acceleration of 6MV X-bands
Pipe, collimater 4 is multi-diaphragm collimator（MLC）, target organ positioning detection device 6 is X-ray image tracking, guiding, positioner, is controlled
It is that remaining is the same as embodiment one outside oncotherapy planning system to treat planning system.
Oncotherapy planning system is divided into lower part：
Speed meets the high-precision dose calculation methodology (including monte carlo method) of clinical requirement；
Automatic profile based on artificial intelligence is delineated；
Quick plan based on big data experience；
Non-co-planar more wild focus on of 4 π plan reverse engineer system；
4D adaptive plannings.
Embodiment three
The accurate Stereotactic Radiosurgery device of this example, for heart disease (such as atrial fibrillation, hypertrophic cardiomyopathy etc.) or
Surgical treatment or as X knives, except treatment planning systems are heart radiosurgery planning system and oncotherapy plan system
System is outer, and remaining is the same as embodiment one.
Oncotherapy planning system is divided into lower part：
Speed meets the high-precision dose calculation methodology (including monte carlo method) of clinical requirement；
Automatic profile based on artificial intelligence is delineated；
Quick plan based on big data experience；
Non-co-planar more wild focus on of 4 π plan reverse engineer system；
4D adaptive plannings.
Claims (10)
- A kind of 1. precisely Stereotactic Radiosurgery device, mainly by radiation appliance system, sextuple robot therapeutic bed （1）, target organ positioning detection device（6）Formed with treatment planning systems；It is characterized in that the radiology system is by frame（12） With C-shaped horn（5）Form, frame（12）On be provided with rotating shaft（10）, rotating shaft（10）With guide rail（9）Connect and control guide rail（9） Rotation, C-shaped horn（5）Installed in guide rail（9）It is upper and along guide rail（9）Carry out arcuate movement；C-shaped horn（5）One end is provided with Radiographic source（2）, radiographic source（2）Bottom is provided with small handpiece（3）, small handpiece（3）Bottom is provided with collimater（4）；C-shaped horn （5）The other end is provided with scalable electronic portal image device（7）Balancing weight is protected with portable shielding（8）；Target organ positioning is visited Survey device（6）Installed in sextuple robot therapeutic bed（1）Bed surface side or lower section.
- 2. accurate Stereotactic Radiosurgery device according to claim 1, it is characterised in that the frame（12）On It is provided with radiographic source auxiliary member（11）.
- 3. accurate Stereotactic Radiosurgery device according to claim 1, it is characterised in that the radiographic source（2）'s Accelerating tube is C-band or X-band；The collimater（4）For circular collimater or multi-diaphragm collimator.
- 4. accurate Stereotactic Radiosurgery device according to claim 1, it is characterised in that the target organ positioning Detection device（6）For X-ray image tracking, guiding, positioner or the tracking of non-X-ray image, guiding, positioner；Wherein, non-X Line image tracking, guiding, positioner are that three-dimensional electrolysis cuts open the emerging system and magnetic conductance of Mapping System and three-dimensional intracardiac echocardiography Boat automatic station-keeping system.
- 5. accurate Stereotactic Radiosurgery device according to claim 1, it is characterised in that the treatment plan system Unite as heart radiosurgery planning system or/and oncotherapy planning system.
- 6. accurate Stereotactic Radiosurgery device according to claim 5, it is characterised in that the heart radiation is outer Its step of section's treatment planning systems is：The noninvasive acquisition of arrhythmia signal and positioning；By the bioelectrical activity of endocardial three dimensions, reverse calculate determines The focus target area source position of arrhythmia cordis occurs；Fixed point radiation ablation is carried out to the cardiac muscular tissue at source position；The parameter of monitoring fixed point radiation ablation point in real time, the physical parameter and heart tissue ginseng of the collection beam X-ray correlation transmitted Number, and guided according to the parameter of feedback, the transmission of boundling x-ray dose is adjusted or optimizes, to cause arrhythmia cordis Treat more precise and high efficiency；Arrhythmia cordis evaluation system is provided；Excite heart to produce electric signal by non-invasive manner, pinpointed with assisting in Heart is directed at the originated location of arrhythmia cordis with the presence or absence of abnormal electricity physiological signal activity, or evaluation before radiation ablation The fixed point radiation ablation made of cardiac muscular tissue whether really effectively.
- 7. accurate Stereotactic Radiosurgery device according to claim 6, it is characterised in that the arrhythmia cordis letter Number noninvasive acquisition and positioning step, it is specially：The fusion method of Mapping System and three-dimensional intracardiac echocardiography is cutd open or using the noninvasive collection electricity of body surface multiple spot using three-dimensional electrolysis Biosignal processing system and 4D cardiac ultrasonic imaging methods.
- 8. accurate Stereotactic Radiosurgery device according to claim 7, it is characterised in that described using three-dimensional electricity The fusion method of electroanatomical mapping system and three-dimensional intracardiac echocardiography is：The right room side that three-dimensional intracardiac echocardiography probe in Mapping System is placed in heart atrial septum will be cutd open by three-dimensional electrolysis, around its length Axle rotating detector, the fault structure of the heart difference covering of the fan obtained, automatic identification, or artificial crisperding are carried out, by related soft Part, reconstruct the stereo profile of the chambers of the heart.
- 9. accurate Stereotactic Radiosurgery device according to claim 7, it is characterised in that described more using body surface The noninvasive collection electricity physiological signal processing system of point and 4D cardiac ultrasonic imaging methods are：The body surface bioelectrical activity signal detected by the electrode being put at sites is obtained, is obtained by reverse computational methods The bioelectrical activity of endocardial three dimensions, determine the generation position of arrhythmia cordis；Determining device frame, sextuple robot therapeutic bed, collect beam X-ray relevant physical parameter and implement radiation ablation it is optimal Path；The cardiac image that will be obtained by 4D supersonic imaging devices, by multi-modality images fusion processing system, patient is coordinated Some images, image reconstruction is carried out, construct the 3 D anatomical model and VR scenes of the three-dimensional heart and trunk of patient.
- 10. accurate Stereotactic Radiosurgery device according to claim 5, it is characterised in that the oncotherapy meter The system of drawing is divided into lower part：Speed meets the high-precision dose calculation methodology (including monte carlo method) of clinical requirement；Automatic profile based on artificial intelligence is delineated；Quick plan based on big data experience；Non-co-planar more wild focus on of 4 π plan reverse engineer system；4D adaptive plannings.
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|---|---|---|---|
| CN201710688854.7A CN107362464A (en) | 2017-08-13 | 2017-08-13 | Accurate Stereotactic Radiosurgery device |
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