CN107353313B - 新化学实体钙锰福地吡和其他混合金属配合物、制备方法、组合物以及治疗方法 - Google Patents
新化学实体钙锰福地吡和其他混合金属配合物、制备方法、组合物以及治疗方法 Download PDFInfo
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| US9187509B2 (en) | 2012-01-05 | 2015-11-17 | Pled Pharma AB | Calmangafodipir, a new chemical entity, and other mixed metal complexes, methods of preparation, compositions, and methods of treatment |
| KR20150080616A (ko) * | 2012-11-02 | 2015-07-09 | 플레드파르마 에이비 | 암 치료 방법 |
| US10233205B2 (en) | 2015-08-07 | 2019-03-19 | Auburn University | Magnetic resonance imaging contrast agent capable of detecting hydrogen peroxide and reducing reactive oxygen species |
| EP3402475B1 (en) | 2016-01-11 | 2021-10-20 | Egetis Therapeutics AB | Methods and formulations for treatment of and/or protection against acute liver failure and other hepatotoxic conditions |
| CN110139673B (zh) * | 2016-11-14 | 2022-03-22 | 卡尔森图纳投资公司 | 使用非过渡金属配位的二吡哆基化合物以预防和治疗化疗诱发的psn |
| CN117279657A (zh) | 2021-05-18 | 2023-12-22 | 日本株式会社Ltt生物医药 | 用于治疗或预防伴随抗癌剂给药的障碍的医药组合物 |
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|---|---|---|---|---|
| US4933456A (en) * | 1987-05-08 | 1990-06-12 | Salutar, Inc. | Dipyridoxyl phosphate NMRI contrast agents |
| CN102481295A (zh) * | 2009-07-06 | 2012-05-30 | 普莱制药公司 | 利用锰配合物化合物与所述化合物之非锰配合物形式的组合的药物组合物和治疗方法 |
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| US5223243A (en) | 1987-05-08 | 1993-06-29 | Salutar, Inc. | Dipyridoxyl phosphate chelating compound intermediates useful as NMRI contrast agents |
| US5091169A (en) | 1987-05-08 | 1992-02-25 | Salutar, Inc. | Dipyridoxyl phosphate NMRI contrast agent compositions |
| US5403834A (en) * | 1992-12-07 | 1995-04-04 | Eukarion, Inc. | Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease |
| US6204259B1 (en) | 1993-01-14 | 2001-03-20 | Monsanto Company | Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide |
| GB9613182D0 (en) * | 1996-06-24 | 1996-08-28 | Nycomed Imaging As | Method |
| GB9727224D0 (en) | 1997-12-23 | 1998-02-25 | Nycomed Imaging As | Method |
| AU1770299A (en) | 1997-12-23 | 1999-07-19 | Nycomed Imaging As | Nitric oxide releasing chelating agents and their therapeutic use |
| FR2823977B1 (fr) | 2001-04-26 | 2006-12-01 | Univ Rene Descartes | Utilisation du mangafodipir dans le traitement des effets d'un stress oxydatif |
| DE10359628A1 (de) | 2003-12-18 | 2005-07-21 | Oxeno Olefinchemie Gmbh | Katalysator und Verfahren zur Herstellung von 1-Olefinen aus 2-Hydroxyalkanen |
| US20070148154A1 (en) | 2004-12-17 | 2007-06-28 | Universite Rene Descartes (Paris V) | Use of superoxide dismutase mimetics and reductase gultatione in the form of anticancer drugs |
| BRPI0820832A2 (pt) * | 2007-12-14 | 2015-06-16 | Pledpharma Ab | Composto, uso de um composto, método de tratamento de câncer, composição farmacêutica, kit , e, uso de uma composição farmacêutica. |
| US8414866B2 (en) * | 2007-12-17 | 2013-04-09 | Ge Healthcare As | Method of magnetic resonance imaging of the heart with paramagnetic MN2+ |
| US9187509B2 (en) * | 2012-01-05 | 2015-11-17 | Pled Pharma AB | Calmangafodipir, a new chemical entity, and other mixed metal complexes, methods of preparation, compositions, and methods of treatment |
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Patent Citations (2)
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| US4933456A (en) * | 1987-05-08 | 1990-06-12 | Salutar, Inc. | Dipyridoxyl phosphate NMRI contrast agents |
| CN102481295A (zh) * | 2009-07-06 | 2012-05-30 | 普莱制药公司 | 利用锰配合物化合物与所述化合物之非锰配合物形式的组合的药物组合物和治疗方法 |
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