CN107320625A - It is absorbed in liver protection shield kidney Chinese medicine health-care formula of sub-health population and preparation method thereof - Google Patents
It is absorbed in liver protection shield kidney Chinese medicine health-care formula of sub-health population and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
- A61K36/066—Clavicipitaceae
- A61K36/068—Cordyceps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Abstract
The invention discloses a kind of liver protection shield kidney Chinese medicine health-care formula for being absorbed in sub-health population and preparation method thereof, it is characterised in that:The Chinese medicine preparation raw material is mainly prepared from the following raw materials in parts by weight:The parts by weight of wolfberry fruit extract 25 45, the parts by weight of ginseng extract 10 20, the parts by weight of Cordyceps militaris extract 25 45, the parts by weight of Rhizoma Polygonati extract 5 15, the parts by weight of orange peel extract 1 10.The present invention limits the content for being constituted each main component in the way of extract first; the limiting mode can ensure that each component consumption is more accurate, realize solid of preferably refreshing oneself, production of sperm tonifying Qi, protection liver kidney antisitic defect and can also effectively improve the technique effect of human immunological competence.
Description
Technical field
The present invention relates to Chinese medicine health-care technical field, it is specifically related in a kind of liver protection shield kidney for being absorbed in sub-health population
Medicine health care formula and preparation method thereof.
Background technology
With the continuous quickening of modern life rhythm, working and learning pressure is continuously increased, it is impossible to rational diet and
Work and rest, causes many people all in sub-health state, inferior health principal character is shown as:Unconformable sensation is reflected on body and mind
A variety of symptoms out, such as fatigue, weak, mood change, its situation are difficult to clearly within suitable period;Do not fitted mutually with the age
Various weak performances caused by institutional framework or the physiological function decline answered;Dysbiosis state;The sick previous existence of some diseases
Manage pathological change.Clinical manifestation is varied, and fatigue and weak, muscle and joint pain, dizzy head are can behave as in terms of body
Bitterly, palpitaition is uncomfortable in chest, sleep disordered, poor appetite, gastral cavity abdomen discomfort, loose stool constipation, hypogona dism, cold To Be Protected from Heat, be easy to flu,
Eye is dry and astringent etc.;Psychological aspects can be presented with it is depressed, upset, lather, being irritable and getting angry easily, frightened timid, memory
Power declines, notice can not be concentrated, deficient in energy, slow in reacting etc.;It can be presented with preferably undertaking in terms of social interaction
Corresponding social role, work, difficulty of learning, it is impossible to normally handle interpersonal relationships, family relationship well, it is difficult to carry out normal
Social interaction etc..And if inferior health timely can not be adjusted and nurse one's health, it will development is increasingly severe, is the hair of disease
Life hides some dangers for.
At present, prior art also reports many health products for being directed to inferior health, and the sub-health state of human body is carried out
Adjustment, such as a kind of entitled formula of herbal tea dedicated for nursing one's health kidney type inferior health, Application No.
201410402798.2 patent application document, its component is mainly by walnut kernel, the fruit of Chinese wolfberry, raw pearl barley, Gorgon fruit, raw peanut
Benevolence, almond, Semen sesami nigrum, chrysanthemum, Sang mulberrys, Zhu's cornus, the fruit of Chinese magnoliavine, Gui Yuan, hawthorn composition.The component of this health product is generally food
Category material, if its health-care effect necessarily compares, can not play the purpose of good conditioning subhealthy state.In addition, denomination of invention
For a kind of traditional Chinese medicine health care preparation of conditioning subhealth state, the patent application document of Application No. 201510983812.7, be with
Semen Lablab Album, Poria cocos, Chinese yam, oyster, walnut kernel, the fruit of Chinese wolfberry, fructus alpiniae oxyphyllae, raspberry, mulberry fruit, the membrane of a chicken's gizzard are bulk drug, by medicament
The oral preparations that common process and auxiliary material is prepared into.Although being said in this health care preparation application documents with strong to human body Asia
Health state has conditioning and mitigation well.Simultaneously because the Chinese medicine of integration of drinking and medicinal herbs is used for raw material, with abundant
Nutritive value and excellent healthcare function, but be a kind of Chinese medicine preparation after all, take very inconvenient, and also do not meet
The taste demand of young crowd.
In addition, present young man stays up late, phenomenon is also increasingly severe, and the health product Chinese medicine of these above-mentioned medicinal liquor classes
Smell and vinosity are too dense, are not liked by young man, and they are more concerned with being refreshed oneself with coffee, but coffee only has
Refreshing effect, and can not play good health care for the damage due to the positions such as the caused heart, brain, kidney, liver, four limbs of staying up late
And tonic effect, on the contrary long-term or excessive drink can also cause tinnitus cardiac muscle hyperfunction (heartbeat is rapid, and pulse rate increases
Plus), and the unequal deficiency of beat pulse, it is not the first choice for the crowd of staying up late.
The content of the invention
The present invention for prior art above-mentioned deficiency there is provided a kind of mouthfeel with ginseng, youth is stayed up late crowd or Asia
Healthy population acceptance is high, and the solid that can refresh oneself, production of sperm tonifying Qi, protection liver kidney antisitic defect and can also effectively improve people
The liver protection for the being absorbed in sub-health population shield kidney Chinese medicine health-care formula of body immunocompetence.
In order to solve the above technical problems, the technical solution adopted by the present invention is:A kind of liver protection for being absorbed in sub-health population
Kidney Chinese medicine health-care formula is protected, the Chinese medicine is mainly prepared from the following raw materials in parts by weight:Wolfberry fruit extract 25-45 parts by weight, people
Conopsea extraction 10-20 parts by weight, Cordyceps militaris extract 25-45 parts by weight, Rhizoma Polygonati extract 5-15 parts by weight, orange peel (tangerine peel or
Dried orange peel) extract 1-10 parts by weight.
Preferably, the described liver protection for being absorbed in sub-health population shield kidney Chinese medicine health-care formula, the products material includes:
The Chinese medicine preparation raw material mainly includes:Wolfberry fruit extract 30-40 parts by weight, ginseng extract 12-18 parts by weight, Cordyceps militaris is extracted
Thing 30-38 parts by weight, Rhizoma Polygonati extract 6-13 parts by weight, orange peel (tangerine peel or dried orange peel) extract 1-10 parts by weight.
As further preferred, the described liver protection for being absorbed in sub-health population shield kidney Chinese medicine health-care formula, the Chinese medicine is matched somebody with somebody
Square raw material mainly includes:Wolfberry fruit extract 33-36 parts by weight, ginseng extract 14-17 parts by weight, Cordyceps militaris extract 32-37
Parts by weight, Rhizoma Polygonati extract 8-12 parts by weight, orange peel (tangerine peel or dried orange peel) extract 4-6 parts by weight.
As a kind of embodiment, the described liver protection for being absorbed in sub-health population shield kidney Chinese medicine health-care formula, the Chinese medicine is matched somebody with somebody
Square raw material mainly includes:The parts by weight of wolfberry fruit extract 35, the parts by weight of ginseng extract 15, the parts by weight of Cordyceps militaris extract 35 are yellow
The parts by weight of essence extract 10, the parts by weight of orange peel extract 5.
The recovery rate of the above-mentioned wolfberry fruit extract of the present invention is controlled within 40%, and the recovery rate control of ginseng extract exists
Within 20%, the recovery rate of Cordyceps militaris extract is controlled within 35%, and the recovery rate of Rhizoma Polygonati extract is controlled within 35%,
The recovery rate of orange peel (tangerine peel or dried orange peel) extract is controlled within 20%.
The extract of the above-mentioned each component of the present invention, is specifically obtained using water extraction-concentration-vacuum drying.Described carries
Take weight of the computational methods of rate for the weight after vacuum drying than the upper raw material without before extracting to obtain, such as matrimony vine
Within recovery rate 40%, percentage obtained from referring to the weight of weight that final vacuum drying obtains divided by matrimony vine raw material contains
Amount.
The Chinese medicine preparation can be prepared into solid beverage preparation, soft drink agent, tablet, capsule, granule.
The present invention also provides a kind of preparation method of the above-mentioned liver protection shield kidney Chinese medicine health-care formula for being absorbed in sub-health population,
Specific preparation process includes:
(1) various raw materials are handled as follows respectively first:Matrimony vine or ginseng or Cordyceps militaris or sealwort or orange peel are claimed
In weight, the water that 3-10 times of its weight is placed in first, heating boils extraction filtering in 1-3 hours and obtains extract solution;It is secondary that to be placed in its heavy
In the water of 3-10 times of amount, 1-3 hours filtering acquisition extract solutions of extraction are boiled in then heating;The water for being placed in 3-5 times of its weight three times
In, 1-2 hours filtering acquisition extract solutions of extraction are boiled in then heating;The extract solution that merging is three times;
(2) extract solution of the various raw materials and then by step (1) obtained is concentrated, that is, is placed in the extractor that is concentrated under reduced pressure
In, vacuum 0.04-0.08MPa is controlled, extract solution is concentrated into the 1-10% of extracting liquid volume by 45-70 DEG C of temperature;
(3) concentrate for each raw material for obtaining step (2) is dried in vacuo, control vacuum 0.04-
0.08MPa, 40-60 DEG C of temperature is concentrated into water content less than less than 10%, obtains the extract of each raw material;
(4) by the extract of each raw material according to formula rate:Wolfberry fruit extract 25-45 parts by weight, ginseng extract 10-
20 parts by weight, Cordyceps militaris extract 25-45 parts by weight, Rhizoma Polygonati extract 5-15 parts by weight, orange peel extract 1-10 parts by weight;Enter
Row mixing granulation;Solid beverage preparation, granule add soluble starch, the addition of soluble starch in processes of mixing and granulating
For the 5-20% of each above-mentioned extract total amount;Tablet, capsule add cornstarch during mixing granulation, and corn forms sediment
The addition of powder is the 20%-50% of each above-mentioned extract total amount, constitutes final various dosage form products.
Above-mentioned steps (3) of the present invention vacuum drying, can be divided into for three stages is dried, first stage, vacuum degree control
In 0.04-0.07MPa, 40-50 DEG C of temperature;Second stage, vacuum degree control is in 0.06-0.08MPa, 40-55 DEG C of temperature;3rd
In the stage, vacuum degree control is in 0.07-0.08MPa, 55-60 DEG C of temperature.
The advantages of the present invention:
(1) present invention limits the content for being constituted each main component in the way of extract first, and the limiting mode can be with
Ensure that each component consumption is more accurate, realize solid of preferably refreshing oneself, production of sperm tonifying Qi, protection liver kidney antisitic defect and can also have
Effect improves the technique effect of human immunological competence.
(2) present invention is not only made by strictly controlling the content of each raw extract and the recovery rate of extract
The Chinese medicine preparation that must be prepared has ginseng smell so that the acceptance of young audient is higher, and effective conditioning subhealth state simultaneously makes
Fitness is obtained effectively to be lifted;Simultaneously, moreover it is possible to effectively alleviate or reduce the various risks stayed up late and brought, effectively lifting is endured
The fitness of night crowd;It is more green strong without any chemical reagent and raw material of the present invention uses All Pure Nature Chinese medicine
Health.
(3) preparation method of the invention, using water extraction, concentration and the step of be dried in vacuo, particularly the vacuum in later stage is done
Dry, the activity of each material effective component, its effect of the performance of maximum possible is effectively ensured in temperature low energy;Vacuum drying is adopted simultaneously
With the processing mode of three-stage, the Precise levels of moisture evaporation speed and active ingredient more can be effectively controlled, farthest
Retain the content of active ingredient, realize solid of preferably refreshing oneself, production of sperm tonifying Qi, protection liver kidney antisitic defect and can also effectively carry
The sub-health state of the technique effect of high human immunological competence, effectively conditioning human body, obtains more healthy fitness.
Embodiment:
Example is given below the present invention is further described, but the embodiment not limited to this of invention.It is used
Experimental raw unless otherwise instructed, can be obtained easily in commercial company.
Embodiment 1:
It is absorbed in the liver protection shield kidney Chinese medicine health-care formula of sub-health population, the products material includes:The weight of wolfberry fruit extract 35
Amount part, the parts by weight of ginseng extract 15, the parts by weight of Cordyceps militaris extract 35, the parts by weight of Rhizoma Polygonati extract 10, (tangerine peel is old for orange peel
Skin) 5 parts by weight of extract.
The recovery rate of the above-mentioned wolfberry fruit extract of the present invention is controlled within 40%, and the recovery rate control of ginseng extract exists
Within 20%, the recovery rate of Cordyceps militaris extract is controlled within 35%, and the recovery rate of Rhizoma Polygonati extract is controlled within 35%,
The recovery rate of orange peel (tangerine peel or dried orange peel) extract is controlled within 20%.
The extract of the above-mentioned each component of the present invention, is specifically obtained using water extraction-concentration-vacuum drying.Described carries
Take weight of the computational methods of rate for the weight after vacuum drying than the upper raw material without before extracting to obtain, such as matrimony vine
Within recovery rate 40%, percentage obtained from referring to the weight of weight that final vacuum drying obtains divided by matrimony vine raw material contains
Amount.
The present invention also provides a kind of preparation method of the above-mentioned liver protection shield kidney Chinese medicine health-care formula for being absorbed in sub-health population,
Specific preparation process includes:
(1) various raw materials are handled as follows respectively first:Matrimony vine or ginseng or Cordyceps militaris or sealwort or orange peel are claimed
In weight, the water that 6 times of its weight is placed in first, heating boils extraction filtering in 1.5 hours and obtains extract solution;It is secondary to be placed in its weight 6
In water again, 2 hours filtering acquisition extract solutions of extraction are boiled in then heating;It is placed in the water of 6 times of its weight for three times, then heats
Boil extraction filtering in 2 hours and obtain extract solution;The extract solution that merging is three times;
(2) extract solution of the various raw materials and then by step (1) obtained is concentrated, that is, is placed in the extractor that is concentrated under reduced pressure
In, vacuum 0.0.6MPa is controlled, extract solution is concentrated into the 8% of extracting liquid volume by 60-65 DEG C of temperature;
(3) concentrate for each raw material for obtaining step (2) is dried in vacuo, control vacuum 0.04-
0.08MPa, 40-60 DEG C of temperature is concentrated into water content less than less than 5%, obtains the extract of each raw material;
(4) by the extract of each raw material according to formula rate:The parts by weight of wolfberry fruit extract 35, the weight of ginseng extract 15
Part, the parts by weight of Cordyceps militaris extract 35, the parts by weight of Rhizoma Polygonati extract 10, the parts by weight of orange peel (tangerine peel or dried orange peel) extract 5;Carry out
Mixing, mixed process addition starch, the addition of each formulation starch is the proportioning of each above-mentioned extract total amount, is solid respectively
Drink agent, granule add starch 20%, and tablet adds starch 50%, and capsule adds starch 25%, and soft drink agent is without starch, structure
Into final product.
Above-mentioned steps (3) of the present invention vacuum drying, can be divided into for three stages is dried, first stage, vacuum degree control
In 0.07MPa, 45-50 DEG C of temperature;Second stage, vacuum degree control is in 0.08MPa, 50-55 DEG C of temperature;Phase III, vacuum
Degree control is in 0.08MPa, 55-60 DEG C of temperature;The time of whole process is defined by final material water content for 5% or so.
Embodiment 2
It is absorbed in the liver protection shield kidney Chinese medicine health-care formula of sub-health population, the beverage raw material includes:The weight of wolfberry fruit extract 40
Amount part, the parts by weight of ginseng extract 10, the parts by weight of Cordyceps militaris extract 30, the parts by weight of Rhizoma Polygonati extract 10, (tangerine peel is old for orange peel
Skin) 10 parts by weight of extract.Other method be the same as Examples 1.
Embodiment 3
It is absorbed in the liver protection shield kidney Chinese medicine health-care formula of sub-health population, the beverage raw material includes:The weight of wolfberry fruit extract 28
Amount part, the parts by weight of ginseng extract 22, the parts by weight of Cordyceps militaris extract 30, the parts by weight of Rhizoma Polygonati extract 10, (tangerine peel is old for orange peel
Skin) 10 parts by weight of extract.Other method be the same as Examples 1.
Product prepared by the above embodiment of the present invention, in process of production outside standard control parts by weight, strict control people
Join total saponin content 300mg/100g, polyoses content is not less than 20%, it is ensured that product has more preferable antifatigue and liver protecting and kidney invigorating
Effect.
Product prepared by the above embodiment of the present invention, can directly be taken with brewed in hot water as electuary, can be sooner or later each
A bag is taken, the metering of 10g/ bags is continuously taken one month, sub-health state is eliminated, while the symptom brought of staying up late also is eliminated
Or significantly weaken;The product of the present invention is due to strict control ginsenoside content 300mg/100g, and polyoses content is not less than
20%, it is ensured that product has the effect of preferably antifatigue and liver protecting and kidney invigorating;Therefore, the same of conditioning subhealth state is just realized
When eliminate or weaken the symptom brought of staying up late.
Claims (9)
1. a kind of liver protection shield kidney Chinese medicine health-care formula for being absorbed in sub-health population, it is characterised in that:Chinese medicine preparation raw material master
It is prepared from the following raw materials in parts by weight:Wolfberry fruit extract 25-45 parts by weight, ginseng extract 10-20 parts by weight, Cordyceps militaris
Extract 25-45 parts by weight, Rhizoma Polygonati extract 5-15 parts by weight, orange peel extract 1-10 parts by weight.
2. the liver protection shield kidney Chinese medicine health-care formula according to claim 1 for being absorbed in sub-health population, it is characterised in that:Should
Chinese medicine preparation raw material mainly includes:Wolfberry fruit extract 30-40 parts by weight, ginseng extract 12-18 parts by weight, Cordyceps militaris extract
30-38 parts by weight, Rhizoma Polygonati extract 6-13 parts by weight, orange peel extract 1-10 parts by weight.
3. the liver protection shield kidney Chinese medicine health-care formula according to claim 2 for being absorbed in sub-health population, it is characterised in that:Should
Chinese medicine preparation raw material mainly includes:Wolfberry fruit extract 33-36 parts by weight, ginseng extract 14-17 parts by weight, Cordyceps militaris extract
32-37 parts by weight, Rhizoma Polygonati extract 8-12 parts by weight, orange peel extract 4-6 parts by weight.
4. the liver protection shield kidney Chinese medicine health-care formula according to claim 3 for being absorbed in sub-health population, it is characterised in that:Should
Chinese medicine preparation raw material mainly includes:The parts by weight of wolfberry fruit extract 35, the parts by weight of ginseng extract 15, the weight of Cordyceps militaris extract 35
Part, the parts by weight of Rhizoma Polygonati extract 10, the parts by weight of orange peel extract 5.
5. the liver protection for the being absorbed in sub-health population shield kidney Chinese medicine health-care according to claim 1-4 any claims is matched somebody with somebody
Side, it is characterised in that:The recovery rate of described wolfberry fruit extract is controlled within 40%, and the recovery rate control of ginseng extract exists
Within 20%, the recovery rate of Cordyceps militaris extract is controlled within 35%, and the recovery rate of Rhizoma Polygonati extract is controlled within 35%,
The recovery rate of orange peel extract is controlled within 20%.
6. the liver protection for the being absorbed in sub-health population shield kidney Chinese medicine health-care according to claim 1-4 any claims is matched somebody with somebody
Side, it is characterised in that:The extract of each component, is specifically obtained using water extraction-concentration-vacuum drying.
7. the liver protection for the being absorbed in sub-health population shield kidney Chinese medicine health-care formula according to claim 1-4, it is characterised in that:
The Chinese medicine preparation can be prepared into solid beverage preparation, soft drink agent, tablet, capsule, granule.
8. a kind of preparation method for the liver protection shield kidney Chinese medicine health-care formula for being absorbed in sub-health population, it is characterised in that:Specifically
Preparation process includes:
(1) various raw materials are handled as follows respectively first:Matrimony vine or ginseng or Cordyceps militaris or sealwort or orange peel are weighed, it is first
Secondary to be placed in the water of 3-10 times of its weight, heating boils extraction filtering in 1-3 hours and obtains extract solution;It is secondary to be placed in its weight 3-10
In water again, 1-3 hours filtering acquisition extract solutions of extraction are boiled in then heating;It is placed in the water of 3-5 times of its weight for three times, then
Heating boils extraction filtering in 1-2 hours and obtains extract solution;The extract solution that merging is three times;
(2) extract solution of the various raw materials and then by step (1) obtained is concentrated, that is, is placed in and is concentrated under reduced pressure in extractor, is controlled
Extract solution is concentrated into the 1-10% of extracting liquid volume by vacuum 0.04-0.08MPa processed, 45-70 DEG C of temperature;
(3) concentrate for each raw material for obtaining step (2) is dried in vacuo, and controls vacuum 0.04-0.08MPa, temperature
40-60 DEG C of degree is concentrated into water content less than less than 10%, obtains the extract of each raw material;
(4) by the extract of each raw material according to formula rate:Wolfberry fruit extract 25-45 parts by weight, ginseng extract 10-20 weights
Measure part, Cordyceps militaris extract 25-45 parts by weight, Rhizoma Polygonati extract 5-15 parts by weight, orange peel extract 1-10 parts by weight;Mixed
Close granulation;Solid beverage preparation, granule add soluble starch in processes of mixing and granulating, and the addition of soluble starch is upper
State the 5-20% of each extract total amount;Tablet, capsule add cornstarch during mixing granulation, cornstarch
Addition is the 20%-50% of each above-mentioned extract total amount, constitutes final various dosage form products.
9. the preparation method of the solid Chinese herbal medicine beverage according to claim 8 for preventing hepar damnification from improving immunocompetence, its
It is characterised by:The step (3) vacuum drying, being divided into for three stages is dried, and the first stage, vacuum degree control is in 0.04-
0.07MPa, 40-50 DEG C of temperature;Second stage, vacuum degree control is in 0.06-0.08MPa, 40-55 DEG C of temperature;Phase III, very
Reciprocal of duty cycle is controlled in 0.07-0.08MPa, 55-60 DEG C of temperature.
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CN102399666A (en) * | 2011-08-26 | 2012-04-04 | 吉林紫鑫药业股份有限公司 | Ginseng wine and production technology thereof |
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