CN107320219A - Aortic root valved conduit device - Google Patents
Aortic root valved conduit device Download PDFInfo
- Publication number
- CN107320219A CN107320219A CN201710532709.XA CN201710532709A CN107320219A CN 107320219 A CN107320219 A CN 107320219A CN 201710532709 A CN201710532709 A CN 201710532709A CN 107320219 A CN107320219 A CN 107320219A
- Authority
- CN
- China
- Prior art keywords
- aortic
- nickel titanium
- sinus
- biovalve
- replacement portion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2427—Devices for manipulating or deploying heart valves during implantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0025—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
- A61F2220/0041—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements using additional screws, bolts, dowels or rivets, e.g. connecting screws
Abstract
The present invention relates to aortic root valved conduit device, transplanting pipeline includes aorta ascendens and replaces pipe and aortic sinus replacement portion；Biovalve includes bovine pericardium and nickel titanium stents, and nickel titanium stents are located at the outside of bovine pericardium, wrap bovine pericardium；Biovalve is placed in aortic sinus replacement portion by dilator, and by dilator strut after be close to the inwall in aortic sinus replacement portion, the height of nickel titanium stents is more than the height in aortic sinus replacement portion, and nickel titanium stents are divided into ascending aortic segment and aortic sinus section.The present invention is shortened aortic root operating time, biocompatibility is improved with biovalve, reduction mechanical prosthetic valve anti-freezing brings side effect.
Description
Technical field
It is particularly a kind of to shorten aortic root operating time, carried with biovalve the present invention relates to medical instruments field
High-biocompatibility, reduction mechanical prosthetic valve anti-freezing bring the aortic root of side effect valved conduit device.
Background technology
Aortic root disease includes influence aorta petal, aortic valvular ring, the disease that aortic sinus and sinus pipe have a common boundary,
In part, the genetic disease such as patient such as Marfan syndromes, Loyes-Diets syndromes often merges aorta ascendens and sustainer
Sinus is expanded, and the patient of other diseases such as syphilitic arteritis, aorto-arteritis and Behcet's disease also usually merges aortic root
Lesion.The incidence more and more higher of hypertension and atherosclerosis now so that the incidence of dissection of aorta is increasingly
Increase, and dissection of aorta case fatality rate and disability rate are high, seriously jeopardize human health.
Traditional modus operandi：Patient for merging the expansion of aorta ascendens sinus or lesion and aortic valve disease,
Often need to go more complicated aortic root operation, it is the more commonly used as valved conduit row Bentall operations, or row retain
The aortic valve replacement of aortic sinus+aorta ascendens replacement operation (Wheat operations), and retain itself aorta petal
David performs the operation.Bentall operations are due to simple to operate, but because displacement is mechanical prosthetic valve, to patients ' life quality and anti-freezing
Aspect brings certain influence, although and David operations retain native valve, due to complex operation, pole is required to operation skill
Height, prolonged extracorporal circulatory system has a strong impact on to postoperative bring, and postoperative complications are high.
In recent years with the development of technology and material, novel seamless closes (sutureless) aorta petal and initially enters clinic
Using.Have without suture aorta petal：1st, the lower excision diseased valve of surgery direct-view, and accurate positioning；2nd, can mini-incision approach；
3rd, need not or it suture a little, many advantages, such as greatly shortening extracorporal circulatory system and operating time becomes high-risk gerontal patient AVR hands
The selection of art newly.At present, what the valve and Nitinol that conventional Pereeval S aorta petals are made including bovine pericardium were made
Cage type support.Holder part is made up of the connecting elements of proximally and distally two annular sections and numerous support valves so that whole
Individual implanted device can be anchored in the coronary sinus of aortic root.Deformation caused by Nitinol can tolerate external force can simultaneously be removed in external force
Restored to the original state after removing, therefore the aorta petal can be crispaturaed into conveyer.And simple suture valve of exempting from is only applicable to list
The patient of pure aortic valve disease, the operative treatment for needing row aorta ascendens to replace for merging aorta ascendens disease is then more stranded
It is difficult.
Bentall operating substitutions for mechanical prosthetic valve, to patients ' life quality and anti-freezing in terms of bring certain influence；
Although David operations retain native valve, due to complex operation, high, prolonged extracorporal circulatory system is required to operation skill
Had a strong impact on to postoperative bring, postoperative complications are high.Exempt to suture the patient that valve is applied to serious Aortic disease, it is right
Need the operative treatment of row aorta ascendens displacement then more difficult in merging aorta ascendens disease.
Chinese patent CN200620175187.X, discloses a kind of manpower biological pulmonary artery lead valve pipeline, including one section of band
There is the bovine jugular vein blood vessel of venous valve, the pipeline that one or two bovine pericardial tissue material is made is connected to the bovine jugular vein blood
The upper end of pipe or upper/lower terminal, the problems such as to solve pipeline valvular inadequacy and second operation excessive adhesion, Authorization Notice No.
For CN200987711Y.
Chinese patent CN201120397678.X, discloses a kind of point of artificial valve two of the asymmetric chamber fixed structure of band
Valve overlay film frame, ultra-thin polytetrafluoroethylene (PTFE) is covered outside with asymmetric chamber fixed system support, the valve in it and support
Film is constituted.By commercially produced product pig or bovine pericardium, manually sewing is formed valve, forms three first quarter moon sinus, Authorization Notice No. is
CN202313807U。
It is badly in need of a kind of shortening aortic root operating time, biocompatibility is improved with biovalve, machine is reduced in this area
Tool valve anti-freezing brings the aortic root of side effect valved conduit device.
The content of the invention
Shorten aortic root operating time it is an object of the invention to provide one kind, bio-compatible is improved with biovalve
Property, reduce mechanical prosthetic valve anti-freezing bring the aortic root of side effect valved conduit device.
Aortic root valved conduit device, including：
Pipeline is transplanted, the transplanting pipeline includes aorta ascendens and replaces pipe and aortic sinus replacement portion, the aorta ascendens
It is hard and flexible tubulose (being preferably what terylene was made) to replace pipe, and the aortic sinus alternative site is replaced in aorta ascendens
One end of pipe, outwardly convex are changed, maximum outside diameter is more than the external diameter that aorta ascendens replaces pipe, and outside is arcuation, and bottom is provided with outside
The connecting portion of protrusion；
Biovalve, the biovalve includes bovine pericardium and nickel titanium stents, and the nickel titanium stents are located at the outer of bovine pericardium
Portion, wraps bovine pericardium；
The biovalve is placed in aortic sinus replacement portion by dilator, and by dilator strut after be close to sustainer
The inwall in sinus replacement portion, the height of the nickel titanium stents is more than the height in aortic sinus replacement portion, and the nickel titanium stents are divided into liter
Aortic segment and aortic sinus section.
It is telescopic bellows that the aorta ascendens, which replaces pipe,.
Biovalve and aortic sinus the replacement portion is fixed by rivet line, and the quantity of the rivet line is more than three.
The ascending aortic segment of the nickel titanium stents is netted.
The ascending aortic segment of the nickel titanium stents is vertically vertical bar, is connected laterally across horizontal folding bar.
The aortic sinus section of the nickel titanium stents is connected laterally across horizontal folding bar, is vertically connected by vertical folding bar.
The aortic sinus section of the nickel titanium stents is elastic strip, and the elastic strip is vertically arranged.
The bottom external diameter of the biovalve is more than the bottom external diameter in aortic sinus replacement portion.
The bovine pericardium is the tubulose biovalve of bovine pericardium material, and the present invention can use the bovine pericardium of commercially produced product,
Such as 6900PW25 of external Enovacor APS (Edwards Lifesciences LLC.), 6900PM27,
6900PM29,6900PM31 or 6900PM33；And for example one hundred domestic benevolence think of (BalMedic) bovine pericardium biovalve, Beijing are general
Bovine pericardium of favour biomedical engineering Co., Ltd etc..
It is preferred that, the bovine pericardium is dehydrated and anti-calcification processing by glutaraldehyde cross-linking, end-capping reagent processing, glycerite.
Present invention transplanting pipeline includes aorta ascendens and replaces pipe and aortic sinus replacement portion, and it is terylene that aorta ascendens, which replaces pipe,
Hard and flexible the tubulose being made, aortic sinus alternative site replaces one end of pipe in aorta ascendens, and outwardly convex is maximum
External diameter is more than the external diameter that aorta ascendens replaces pipe, and outside is arcuation；Biovalve includes bovine pericardium and nickel titanium stents, and bovine pericardium is
The tubulose biovalve of bovine pericardium material, nickel titanium stents are located at the outside of bovine pericardium, wrap bovine pericardium；Biovalve leads to
Dilator is crossed to be placed in aortic sinus replacement portion, and by dilator strut after be close to the inwall in aortic sinus replacement portion, NiTi branch
The height of frame is more than the height in aortic sinus replacement portion, and nickel titanium stents are divided into ascending aortic segment and aortic sinus section.Aorta ascendens
The cooperation in pipe and aortic sinus replacement portion is replaced, shortens aortic root operating time；Tradition machinery valve is replaced with biovalve
Film, biocompatibility is more preferable；Reduce the side effect that mechanical prosthetic valve anti-freezing is brought.Suitable for needing row aorta ascendens replacement union sustainer
The operative treatment of the patient of valve lesion.The present invention shortened aortic root operating time, biocompatibility is improved with biovalve,
Reduce mechanical prosthetic valve anti-freezing and bring side effect.
Brief description of the drawings
Fig. 1 is diagrammatic cross-section of the invention；
Fig. 2 transplants the front view of pipeline for the present invention；
Fig. 3 is the present invention with horizontal folding bar, the nickel titanium stents front view of vertical folding bar；
Fig. 4 carries the nickel titanium stents stereogram of elastic strip for the present invention；
In figure：1st, transplant pipeline, 2, biovalve, 11, aorta ascendens replace pipe, 12, aortic sinus replacement portion, 21, ox
Pericardium, 22, nickel titanium stents, 23, horizontal folding bar, 24, vertical folding bar, 25, elastic strip.
Embodiment
Below in conjunction with the drawings and specific embodiments, the present invention will be further described.
Embodiment 1：
Aortic root valved conduit device, including：Pipeline 1 is transplanted, transplanting pipeline 1 includes aorta ascendens and replaces pipe 11
With aortic sinus replacement portion 12, it is hard and flexible the tubulose that terylene is made that aorta ascendens, which replaces pipe 11, and aortic sinus is replaced
One end that portion 12 replaces pipe 11 positioned at aorta ascendens is changed, outwardly convex, maximum outside diameter is more than the external diameter that aorta ascendens replaces pipe 11,
Outside is arcuation, and bottom is provided with outwardly connecting portion；Biovalve 2, biovalve 2 includes bovine pericardium 21 and nickel titanium stents
22, bovine pericardium 21 is the tubulose biovalve of bovine pericardium material, and nickel titanium stents 22 are located at the outside of bovine pericardium 21, wrapped
Bovine pericardium 21；Biovalve 2 is placed in aortic sinus replacement portion 12 by dilator, and by dilator strut after be close to sustainer
The inwall in sinus replacement portion 12, the height of nickel titanium stents 22 is more than the height in aortic sinus replacement portion 12, and 22 points of nickel titanium stents are liter
Aortic segment and aortic sinus section.
It is telescopic bellows that aorta ascendens, which replaces pipe 11,.Biovalve 2 and aortic sinus replacement portion 12 are by rivet line
Fixed, the quantity of rivet line is more than three.The ascending aortic segment of nickel titanium stents 22 is netted.The aorta ascendens of nickel titanium stents 22
Duan Shuxiang is vertical bar, is connected laterally across horizontal folding bar 23.The aortic sinus section of nickel titanium stents 22 is laterally across horizontal folding bar
23 connections, are vertically connected by vertical folding bar 24.The aortic sinus section of nickel titanium stents 22 is elastic strip 25, and elastic strip 25 is vertically set
Put.The bottom external diameter of biovalve 2 is more than the bottom external diameter in aortic sinus replacement portion 12.Bovine pericardium 21 is by glutaraldehyde cross-linking, envelope
Hold agent processing, glycerite dehydration and anti-calcification processing.
Device is broadly divided into transplanting pipeline 1 and biovalve 2, and transplanting pipeline 1 is pipeline graft, is mainly used in replacing disease
The aorta ascendens of change, it is mainly made up of polyester material, hard and flexible, and with different model sizes, upper end is led to rise
Artery replaces pipe 11, can be cut according to length, has aortic sinus replacement at the nearly ascending aorta near-end stapling mouthful in its lower end
Portion 12, is the sinus portion expansion in the similar aortic sinus portion of a circle outwardly convex, for simulating aortic root blood under physiological conditions
Stream, this sinus portion expansion mainly exempts to suture the release position of biovalve, it is ensured that valve rivet is firmly, difficult for drop-off；
Biovalve 2 is broadly divided into bovine pericardium 21 and nickel titanium stents 22, bovine pericardium to exempt to suture aorta petal biovalve
21 be inner core, i.e. biovalve, and it is using bovine pericardium as material, and other aldehyde using glutaraldehyde or containing medicament are crosslinked, use end-capping reagent
Handle and be dehydrated with glycerite, and pass through special anti-calcification processing, it is ensured that it uses permanence；Nickel titanium stents 22 are nickel
Titanium memorial alloy support arm, it is in netted parcel biovalve, and compressive state is in using preceding.The memorial alloy when in use,
It can be strutted by hand-held dilator, expand and expand valve, be at physiological status, memorial alloy is from as support
Support, is released to profile and is adapted in the expansion in gillies' graft sinus portion after expanding.
End-capping reagent crosses pillar with alkali alumina, or first with 5% NaOH aqueous solution cyclic washings, desiccant dryness removes
Vacuum distillation after water.Sealed using the polyglycidyl compounds for having protected functional group such as acetal radical as end-capping reagent
Anionic polymer is held, the polymer of functionalization is produced.Protected functional group be all under various conditions it is stable, then very
Easily change into the reactive higher terminal functional group for being applicable production adhesive, sealant and coating.
Chief surgical step is：Lesion aorta ascendens and sinus portion are cut off, diseased aortic is cut off, pipeline 1 will be transplanted
It is seamed at annulus, the biovalve 2 of suitable size is chosen after suture, directly release is fixed to the sinus portion of gillies' graft
Three rivet lines, test of fetching water completes the displacement of aorta ascendens and biovalve, operating time is compared to traditional operation significantly
Save.
Shorten aortic root operating time；Tradition machinery valve is replaced with biovalve, biocompatibility is more preferable；Reduce
The side effect that mechanical prosthetic valve anti-freezing is brought.The operation of patient suitable for needing row aorta ascendens replacement union aortic valve disease is controlled
Treat.
Dilator is pneumatic, upon inflation, struts and partially opens as predetermined shape, during deflation, struts part and reverts to
Original state, will strut part and extend into the position that needs are strutted, inflation is strutted, and is taken out after then deflating when using.
The basic principles, principal features and advantages of the present invention have been shown and described above.The technical staff of the industry should
Understand, the present invention is not limited to the above embodiments, the original for simply illustrating the present invention described in above-described embodiment and specification
Reason, various changes and modifications of the present invention are possible without departing from the spirit and scope of the present invention, these changes and improvements
It all fall within the protetion scope of the claimed invention.The claimed scope of the invention is by appended claims and its equivalent circle
It is fixed.
Claims (9)
1. aortic root valved conduit device, it is characterised in that including：
Pipeline (1) is transplanted, the transplanting pipeline (1) includes aorta ascendens and replaces pipe (11) and aortic sinus replacement portion (12), institute
It is hard and flexible tubulose to state aorta ascendens and replace pipe (11), and the aortic sinus replacement portion (12) is replaced positioned at aorta ascendens
One end of pipe (11) is changed, outwardly convex, maximum outside diameter is more than the external diameter that aorta ascendens replaces pipe (11), and outside is arcuation, bottom
Provided with outwardly connecting portion；
Biovalve (2), the biovalve (2) includes bovine pericardium (21) and nickel titanium stents (22), the nickel titanium stents (22)
Outside positioned at bovine pericardium (21), wraps bovine pericardium (21)；
The biovalve (2) is placed in aortic sinus replacement portion (12) by dilator, and by dilator strut after be close to master
The inwall in artery sinus replacement portion (12), the height of the nickel titanium stents (22) is more than the height in aortic sinus replacement portion (12), institute
State nickel titanium stents (22) and be divided into ascending aortic segment and aortic sinus section.
2. aortic root according to claim 1 valved conduit device, it is characterised in that the aorta ascendens is replaced
It is telescopic bellows to manage (11).
3. aortic root according to claim 1 valved conduit device, it is characterised in that the biovalve (2)
Fixed with aortic sinus replacement portion (12) by rivet line, the quantity of the rivet line is more than three.
4. aortic root according to claim 1 valved conduit device, it is characterised in that the nickel titanium stents (22)
Ascending aortic segment to be netted.
5. aortic root according to claim 1 valved conduit device, it is characterised in that the nickel titanium stents (22)
Ascending aortic segment vertically be vertical bar, laterally across horizontal folding bar (23) connect.
6. aortic root according to claim 1 valved conduit device, it is characterised in that the nickel titanium stents (22)
Aortic sinus section laterally across horizontal folding bar (23) connect, vertically pass through vertical folding bar (24) connect.
7. aortic root according to claim 1 valved conduit device, it is characterised in that the nickel titanium stents (22)
Aortic sinus section be elastic strip (25), the elastic strip (25) is vertically arranged.
8. aortic root according to claim 1 valved conduit device, it is characterised in that the biovalve (2)
Bottom external diameter be more than aortic sinus replacement portion (12) bottom external diameter.
9. aortic root according to claim 1 valved conduit device, it is characterised in that the bovine pericardium (21) by
Glutaraldehyde cross-linking, end-capping reagent processing, glycerite dehydration and anti-calcification processing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710532709.XA CN107320219A (en) | 2017-07-03 | 2017-07-03 | Aortic root valved conduit device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710532709.XA CN107320219A (en) | 2017-07-03 | 2017-07-03 | Aortic root valved conduit device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107320219A true CN107320219A (en) | 2017-11-07 |
Family
ID=60198565
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710532709.XA Pending CN107320219A (en) | 2017-07-03 | 2017-07-03 | Aortic root valved conduit device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107320219A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113558814A (en) * | 2021-07-28 | 2021-10-29 | 云南省阜外心血管病医院 | Aortic root valved endovascular graft |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113558814A (en) * | 2021-07-28 | 2021-10-29 | 云南省阜外心血管病医院 | Aortic root valved endovascular graft |
| CN113558814B (en) * | 2021-07-28 | 2024-03-15 | 云南省阜外心血管病医院 | Aortic root valve-containing vessel endovascular graft |
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