CN107320218B - Pulmonary artery intervenes the preparation method of valve bracket and pulmonary artery intervention valve - Google Patents

Pulmonary artery intervenes the preparation method of valve bracket and pulmonary artery intervention valve Download PDF

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Publication number
CN107320218B
CN107320218B CN201710486641.6A CN201710486641A CN107320218B CN 107320218 B CN107320218 B CN 107320218B CN 201710486641 A CN201710486641 A CN 201710486641A CN 107320218 B CN107320218 B CN 107320218B
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CN
China
Prior art keywords
pulmonary artery
valve
supporting network
wire
intervenes
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201710486641.6A
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Chinese (zh)
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CN107320218A (en
Inventor
董念国
尚小珂
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Wuhan Wei Ke Medical Technology Co Ltd
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Wuhan Wei Ke Medical Technology Co Ltd
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Priority to CN201710486641.6A priority Critical patent/CN107320218B/en
Publication of CN107320218A publication Critical patent/CN107320218A/en
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Expired - Fee Related legal-status Critical Current
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2412Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2412Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
    • A61F2/2415Manufacturing methods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2412Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
    • A61F2/2418Scaffolds therefor, e.g. support stents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/34Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0004Rounded shapes, e.g. with rounded corners
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2240/00Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2240/001Designing or manufacturing processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/20Materials or treatment for tissue regeneration for reconstruction of the heart, e.g. heart valves

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Manufacturing & Machinery (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)

Abstract

The present invention provides the preparation methods of pulmonary artery intervention valve bracket and pulmonary artery intervention valve, including, the supporting network of three sections of arcuations and the wire with three sections of arcuations;The supporting network is arranged alternately with wire, and connection is annular in shape.The preparation method of pulmonary artery intervention valve bracket and pulmonary artery intervention valve provided by the invention, by the way that novel valve bracket is arranged, so that the intervention valve formed has, the processing is simple, production cost is low, and polyurethane extexine is formed in rack surface, bracket is not good with contacting blood antithrombotic effect, and service life increases.

Description

Pulmonary artery intervenes the preparation method of valve bracket and pulmonary artery intervention valve
Technical field
The present invention relates to heart valve technical fields, more particularly to the system of pulmonary artery intervention valve bracket and pulmonary artery intervention valve Preparation Method.
Background technique
Pulmonary artery valve replacement device in the prior art, the network made of memory metal material, and sewing The three-leaflet valve that can unidirectionally open in the bracket is constituted.But existing pulmonary artery valve replacement device has cost high, fits Answering property is poor, prepares complicated disadvantage.
Summary of the invention
In view of the above drawbacks of the prior art and problem, the purpose of the embodiment of the present invention is that providing pulmonary artery intervenes valve bracket And the preparation method of pulmonary artery intervention valve.
In order to achieve the above object, the invention provides the following technical scheme:
Pulmonary artery intervenes valve bracket, including, the supporting network of three sections of arcuations and the wire with three sections of arcuations;The supporting network It is arranged alternately with wire, connection is annular in shape.
Wherein, the inward at both ends of the wire, which is bent, fastens, and forms close ring;The close ring internal diameter and composition support The braided wires diameter dimension of net is corresponding.
Wherein, the inward at both ends bending direction of the wire is opposite.
Wherein, the supporting network is arc-like sheet through being cut by laser the hollow out shape that assumes diamond in shape;The diamondoid unit cells are single layer.
It wherein, further include flaring ring, the flaring ring is connected to supporting network by support rod.
Wherein, the flaring ring is two, is located at supporting network both ends.
Pulmonary artery intervenes the preparation method of valve, includes the following steps:
S1: pulmonary artery described in any one of claims 1-6 intervention valve bracket is soaked in polyurethane solutions, leaching is used Stain lifts coating method and prepares polyurethane extexine on cylindrical die surface;
S2: taking bovine pericardium valve, and bovine pericardium valve is sutured in wire, obtains pulmonary artery and intervenes valve.
Wherein, the polyurethane solutions mass fraction is 40%.
Wherein, the polyurethane extexine with a thickness of 0.1-3mm.
The preparation method of pulmonary artery intervention valve bracket and pulmonary artery intervention valve provided by the invention, by the way that novel valve is arranged Membrane support, so that the intervention valve formed has, the processing is simple, and production cost is low, and forms polyurethane extexine in rack surface, Bracket is not good with contacting blood antithrombotic effect, and service life increases.
Detailed description of the invention
In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below There is attached drawing needed in technical description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this Some embodiments of invention without any creative labor, may be used also for those of ordinary skill in the art To obtain other drawings based on these drawings.
Fig. 1 is the main view of supporting network of the invention;
Fig. 2 is the top view of wire of the invention;
Fig. 3 is structural schematic diagram of the invention;
Fig. 4 is the structural schematic diagram of another embodiment of the invention;
Fig. 5 is the structural schematic diagram of pulmonary artery intervention valve of the invention.
Specific embodiment
Below in conjunction with the embodiment of the present invention, technical solution of the present invention is clearly and completely described, it is clear that Described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Based on the implementation in the present invention Example, every other embodiment obtained by those of ordinary skill in the art without making creative efforts belong to The scope of protection of the invention.
According to Fig. 1, as embodiment, pulmonary artery intervenes valve bracket.Taking radian is the arc-like sheet of π/3, arc-like sheet Material is memory metal material.Arc-like sheet is cut using laser, is carved, hollow out shape obtains so that arc-like sheet assumes diamond in shape Supporting network 1.Diamondoid unit cells 101 are single layer.As shown in Fig. 2, taking wire 2, wire is arcuation, the inward at both ends of wire Bending, and bending direction is on the contrary, the internal diameter of close ring 201 made of bending fastening and the 102 diameter ruler of braided wires of supporting network 1 It is very little corresponding.Wherein, for the ease of connection, as shown in Fig. 2, 201 plane of close ring and the arc-shaped bend plane of wire are same In plane.As shown in figure 3, three sections of supporting networks 1 and three sections of 2 alternate intervals of wire settings.Supporting network one end is located at wire In the lipostomous of one end, the other end of wire is connect with one end of another supporting network, and it is annular in shape to be sequentially connected closure.Such as Fig. 4 institute Show, further include, extension mouth 3, extension mouth 3 is two, is respectively arranged at supporting network both ends.Supporting network and extension mouth 3 pass through support Bar 4 connects.Connection type is to open up connecting hole 401 respectively by 4 both ends of support rod, is knotted and is supported by flexible binding strap Net is connected with flaring ring.
Pulmonary artery intervenes the preparation method of valve, and pulmonary artery intervention valve bracket 5 is soaked in the poly- ammonia that mass fraction is 40% In ester solution, polyurethane extexine is prepared on cylindrical die surface using Best-Effort request coating method, Best-Effort request coating method is Common knowledge, this will not be repeated here.Polyurethane extexine with a thickness of 0.1-3mm.Bovine pericardium valve is taken, by bovine pericardium valve 6 It is sutured in wire, as shown in figure 5, obtaining pulmonary artery intervenes valve.Bracket is not good with contacting blood antithrombotic effect.Have simultaneously Step is simple compared with the existing technology for production technology, and controllability is stronger, is conducive to batch production.
The above description is merely a specific embodiment, but scope of protection of the present invention is not limited thereto, any Those familiar with the art in the technical scope disclosed by the present invention, can easily think of the change or the replacement, and should all contain Lid is within protection scope of the present invention.Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.

Claims (5)

1. pulmonary artery intervenes valve bracket, it is characterised in that: including, the supporting network of three sections of arcuations, the wire of three sections of arcuations and expansion Choma;The supporting network is arranged alternately with wire, and connection is annular in shape;The flaring ring is connected to supporting network by support rod;
The inward at both ends of the wire, which is bent, to be fastened, and close ring is formed;The close ring internal diameter and the braiding for constituting supporting network Silk diameter dimension is corresponding.
2. pulmonary artery according to claim 1 intervenes valve bracket, it is characterised in that: the inward at both ends of the wire is bent It is contrary.
3. pulmonary artery according to claim 2 intervenes valve bracket, it is characterised in that: the supporting network is arc-like sheet through laser Cut the hollow out shape that assumes diamond in shape;The supporting network is single layer.
4. pulmonary artery according to claim 1 intervenes valve bracket, it is characterised in that: the flaring ring is two, respectively position In supporting network both ends.
5. the preparation method of pulmonary artery intervention valve, which comprises the steps of:
S1: pulmonary artery of any of claims 1-4 intervention valve bracket is soaked in polyurethane solutions, dipping is used Lifting coating method prepares polyurethane extexine on cylindrical die surface, and the polyurethane solutions mass fraction is 40%, described Polyurethane extexine with a thickness of 0.1-3mm;
S2: taking bovine pericardium valve, and bovine pericardium valve is sutured in wire, obtains pulmonary artery and intervenes valve.
CN201710486641.6A 2017-06-23 2017-06-23 Pulmonary artery intervenes the preparation method of valve bracket and pulmonary artery intervention valve Expired - Fee Related CN107320218B (en)

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CN201710486641.6A CN107320218B (en) 2017-06-23 2017-06-23 Pulmonary artery intervenes the preparation method of valve bracket and pulmonary artery intervention valve

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CN201710486641.6A CN107320218B (en) 2017-06-23 2017-06-23 Pulmonary artery intervenes the preparation method of valve bracket and pulmonary artery intervention valve

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CN107320218B true CN107320218B (en) 2019-08-16

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Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109893299B (en) * 2019-04-15 2024-05-31 杭州创心医学科技有限公司 Interventional pulmonary valve and manufacturing method thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2038843A5 (en) * 1969-03-31 1971-01-08 Dassault Electronique Aortic valve support
US6458156B1 (en) * 1996-05-31 2002-10-01 The University Of Western Ontario Expansible bioprosthetic valve stent
CN101222885A (en) * 2005-06-07 2008-07-16 爱德华兹生命科学公司 Systems and methods for assembling components of a fabric-covered prosthetic heart valve
CN104918582A (en) * 2012-12-19 2015-09-16 W.L.戈尔及同仁股份有限公司 Planar zone in prosthetic heart valve leaflet
CN106726008A (en) * 2017-01-04 2017-05-31 周诚 A kind of valve and preparation method thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7547322B2 (en) * 2001-07-19 2009-06-16 The Cleveland Clinic Foundation Prosthetic valve and method for making same
US6893460B2 (en) * 2001-10-11 2005-05-17 Percutaneous Valve Technologies Inc. Implantable prosthetic valve

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2038843A5 (en) * 1969-03-31 1971-01-08 Dassault Electronique Aortic valve support
US6458156B1 (en) * 1996-05-31 2002-10-01 The University Of Western Ontario Expansible bioprosthetic valve stent
CN101222885A (en) * 2005-06-07 2008-07-16 爱德华兹生命科学公司 Systems and methods for assembling components of a fabric-covered prosthetic heart valve
CN104918582A (en) * 2012-12-19 2015-09-16 W.L.戈尔及同仁股份有限公司 Planar zone in prosthetic heart valve leaflet
CN106726008A (en) * 2017-01-04 2017-05-31 周诚 A kind of valve and preparation method thereof

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Applicant after: Wuhan Wei Ke Medical Technology Co., Ltd.

Address before: 430000 1277 Liberation Road, Wuhan, Hubei

Applicant before: Dong Nianguo

Applicant before: Shang Xiaoke

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