CN107320218A - Pulmonary artery intervenes valve support and pulmonary artery intervenes the preparation method of valve - Google Patents

Pulmonary artery intervenes valve support and pulmonary artery intervenes the preparation method of valve Download PDF

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Publication number
CN107320218A
CN107320218A CN201710486641.6A CN201710486641A CN107320218A CN 107320218 A CN107320218 A CN 107320218A CN 201710486641 A CN201710486641 A CN 201710486641A CN 107320218 A CN107320218 A CN 107320218A
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CN
China
Prior art keywords
pulmonary artery
valve
intervenes
wire
supporting network
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201710486641.6A
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Chinese (zh)
Other versions
CN107320218B (en
Inventor
董念国
尚小珂
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Wuhan Wei Ke Medical Technology Co Ltd
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Individual
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Priority to CN201710486641.6A priority Critical patent/CN107320218B/en
Publication of CN107320218A publication Critical patent/CN107320218A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2412Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2412Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
    • A61F2/2415Manufacturing methods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2412Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
    • A61F2/2418Scaffolds therefor, e.g. support stents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/34Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0004Rounded shapes, e.g. with rounded corners
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2240/00Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2240/001Designing or manufacturing processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/20Materials or treatment for tissue regeneration for reconstruction of the heart, e.g. heart valves

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Manufacturing & Machinery (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)

Abstract

The invention provides the preparation method that pulmonary artery intervention valve support and pulmonary artery intervene valve, including, the supporting network of three sections of arcuations and the wire with three sections of arcuations;The supporting network is arranged alternately with wire, and connection is annular in shape.Pulmonary artery intervention valve support and pulmonary artery that the present invention is provided intervene the preparation method of valve, the new valve bracket by setting, so that the intervention valve formed has processing simple, production cost is low, and in rack surface formation polyurethane extexine, support is not good with contacting blood antithrombotic effect, service life increase.

Description

Pulmonary artery intervenes valve support and pulmonary artery intervenes the preparation method of valve
Technical field
The system of valve is intervened the present invention relates to cardiac valves technical field, more particularly to pulmonary artery intervention valve support and pulmonary artery Preparation Method.
Background technology
Pulmonary artery valve replacement device of the prior art, the network being made up of memory metal material, and sewing The three-leaflet valve that can unidirectionally open in the support is constituted.But existing pulmonary artery valve replacement device has cost high, fit Answering property is poor, prepares complicated shortcoming.
The content of the invention
For the drawbacks described above and problem of prior art, the purpose of the embodiment of the present invention is to provide pulmonary artery intervention valve support And pulmonary artery intervenes the preparation method of valve.
In order to achieve the above object, the present invention provides following technical scheme:
Pulmonary artery intervenes valve support, including, the supporting network of three sections of arcuations and the wire with three sections of arcuations;The supporting network It is arranged alternately with wire, connection is annular in shape.
Wherein, the inward at both ends bending of the wire is fastened, and forms close ring;The close ring internal diameter is supported with constituting The braided wires diameter dimension of net is corresponding.
Wherein, the inward at both ends bending direction of the wire is opposite.
Wherein, the supporting network is arc-like sheet through being cut by laser the hollow out shape that assumes diamond in shape;The diamondoid unit cells are individual layer.
Wherein, in addition to, flaring ring, the flaring ring is connected to supporting network by support bar.
Wherein, the flaring ring is two, respectively positioned at supporting network two ends.
Pulmonary artery intervenes the preparation method of valve, comprises the following steps:
S1:Pulmonary artery intervention valve support described in claim any one of 1-6 is soaked in polyurethane solutions, leaching is used Stain lifting coating method prepares polyurethane extexine on cylindrical die surface;
S2:Bovine pericardium valve is taken, bovine pericardium valve is sutured in wire, pulmonary artery intervention valve is obtained.
Wherein, the polyurethane solutions mass fraction is 40%.
Wherein, the thickness of the polyurethane extexine is 0.1-3mm.
Pulmonary artery intervention valve support and pulmonary artery that the present invention is provided intervene the preparation method of valve, the new valve by setting Membrane support so that the intervention valve of formation has processing simple, and production cost is low, and in rack surface formation polyurethane extexine, Support is not good with contacting blood antithrombotic effect, service life increase.
Brief description of the drawings
In order to illustrate more clearly about the embodiment of the present invention or technical scheme of the prior art, below will be to embodiment or existing There is the accompanying drawing used required in technology description to be briefly described, it should be apparent that, drawings in the following description are only this Some embodiments of invention, for those of ordinary skill in the art, without having to pay creative labor, may be used also To obtain other accompanying drawings according to these accompanying drawings.
Fig. 1 is the front view of the supporting network of the present invention;
Fig. 2 is the top view of the wire of the present invention;
Fig. 3 is the structural representation of the present invention;
Fig. 4 is the structural representation of another embodiment of the invention;
Fig. 5 is that the pulmonary artery of the present invention intervenes the structural representation of valve.
Embodiment
Below in conjunction with embodiments of the invention, technical scheme is clearly and completely described, it is clear that Described embodiment is only a part of embodiment of the invention, rather than whole embodiments.Based on the implementation in the present invention Example, the every other embodiment that those of ordinary skill in the art are obtained under the premise of creative work is not made is belonged to The scope of protection of the invention.
According to Fig. 1, embodiment, pulmonary artery intervention valve support are used as.The arc-like sheet that radian is π/3 is taken, arc-like sheet Material is memory metal material.Arc-like sheet is cut using laser, carved so that arc-like sheet assume diamond in shape hollow out shape acquisition Supporting network 1.Diamondoid unit cells 101 are individual layer.As shown in Fig. 2 taking wire 2, wire is arcuation, the inward at both ends of wire Bending, and bending direction is on the contrary, the diameter chi of braided wires 102 of the internal diameter and supporting network 1 for the close ring 201 that bending is fastened It is very little corresponding.Wherein, for the ease of connection, as shown in Fig. 2 the plane of close ring 201 and the arc-shaped bend plane of wire are same In plane.As shown in figure 3, three sections of supporting networks 1 and three sections of alternate intervals of wire 2 are set.Supporting network one end is located at wire In the lipostomous of one end, the other end of wire is connected with one end of another supporting network, is sequentially connected closure annular in shape.Such as Fig. 4 institutes Show, in addition to, extension mouth 3, extension mouth 3 is two, is respectively arranged at supporting network two ends.Supporting network passes through support with extension mouth 3 Bar 4 is connected.Connected mode is to open up connecting hole 401 respectively by the two ends of support bar 4, is knotted by flexible binding strap with supporting Net and flaring ring connection.
Pulmonary artery intervenes the preparation method of valve, and pulmonary artery is intervened into valve support 5 is soaked in the poly- ammonia that mass fraction is 40% In ester solution, polyurethane extexine is prepared on cylindrical die surface using Best-Effort request coating method, Best-Effort request coating method is Common knowledge, will not be described here.The thickness of polyurethane extexine is 0.1-3mm.Bovine pericardium valve is taken, by bovine pericardium valve 6 Wire is sutured in, as shown in figure 5, obtaining pulmonary artery intervention valve.Support is not good with contacting blood antithrombotic effect.Have simultaneously Production technology is simple relative to prior art step, and controllability is stronger, beneficial to batch production.
The foregoing is only a specific embodiment of the invention, but protection scope of the present invention is not limited thereto, any Those familiar with the art the invention discloses technical scope in, change or replacement can be readily occurred in, should all be contained Cover within protection scope of the present invention.Therefore, protection scope of the present invention described should be defined by scope of the claims.

Claims (9)

1. pulmonary artery intervenes valve support, it is characterised in that:Including the supporting network of three sections of arcuations and the wire with three sections of arcuations; The supporting network is arranged alternately with wire, and connection is annular in shape.
2. pulmonary artery according to claim 1 intervenes valve support, it is characterised in that:The inward at both ends bending of the wire Fasten, form close ring;The close ring internal diameter is corresponding to the braided wires diameter dimension for constituting supporting network.
3. pulmonary artery according to claim 2 intervenes valve support, it is characterised in that:The inward at both ends bending of the wire In the opposite direction.
4. pulmonary artery according to claim 3 intervenes valve support, it is characterised in that:The supporting network is arc-like sheet through laser Cut the hollow out shape that assumes diamond in shape;The diamondoid unit cells are individual layer.
5. pulmonary artery according to claim 4 intervenes valve support, it is characterised in that:Also include, flaring ring, the flaring ring Supporting network is connected to by support bar.
6. pulmonary artery according to claim 5 intervenes valve support, it is characterised in that:The flaring ring is two, respectively position In supporting network two ends.
7. pulmonary artery intervenes the preparation method of valve, it is characterised in that comprise the following steps:
S1:Pulmonary artery intervention valve support described in claim any one of 1-6 is soaked in polyurethane solutions, carried using dipping Coating method is drawn to prepare polyurethane extexine on cylindrical die surface;
S2:Bovine pericardium valve is taken, bovine pericardium valve is sutured in wire, pulmonary artery intervention valve is obtained.
8. pulmonary artery according to claim 7 intervenes the preparation method of valve, it is characterised in that:The polyurethane solutions quality Fraction is 40%.
9. pulmonary artery according to claim 8 intervenes the preparation method of valve, it is characterised in that:The polyurethane extexine Thickness is 0.1-3mm.
CN201710486641.6A 2017-06-23 2017-06-23 Pulmonary artery intervenes the preparation method of valve bracket and pulmonary artery intervention valve Expired - Fee Related CN107320218B (en)

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CN201710486641.6A CN107320218B (en) 2017-06-23 2017-06-23 Pulmonary artery intervenes the preparation method of valve bracket and pulmonary artery intervention valve

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CN201710486641.6A CN107320218B (en) 2017-06-23 2017-06-23 Pulmonary artery intervenes the preparation method of valve bracket and pulmonary artery intervention valve

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CN107320218B CN107320218B (en) 2019-08-16

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109893299A (en) * 2019-04-15 2019-06-18 杭州嘉和众邦生物科技有限公司 A kind of intervention pulmonary valve and its manufacturing method

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2038843A5 (en) * 1969-03-31 1971-01-08 Dassault Electronique Aortic valve support
US6458156B1 (en) * 1996-05-31 2002-10-01 The University Of Western Ontario Expansible bioprosthetic valve stent
US20040260390A1 (en) * 2001-07-19 2004-12-23 The Cleveland Clinic Foundation Prosthetic valve and method for making same
US20080004688A1 (en) * 2001-10-11 2008-01-03 Benjamin Spenser Implantable prosthetic valve
CN101222885A (en) * 2005-06-07 2008-07-16 爱德华兹生命科学公司 Systems and methods for assembling components of a fabric-covered prosthetic heart valve
CN104918582A (en) * 2012-12-19 2015-09-16 W.L.戈尔及同仁股份有限公司 Planar zone in prosthetic heart valve leaflet
CN106726008A (en) * 2017-01-04 2017-05-31 周诚 A kind of valve and preparation method thereof

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2038843A5 (en) * 1969-03-31 1971-01-08 Dassault Electronique Aortic valve support
US6458156B1 (en) * 1996-05-31 2002-10-01 The University Of Western Ontario Expansible bioprosthetic valve stent
US20040260390A1 (en) * 2001-07-19 2004-12-23 The Cleveland Clinic Foundation Prosthetic valve and method for making same
US20080004688A1 (en) * 2001-10-11 2008-01-03 Benjamin Spenser Implantable prosthetic valve
CN101222885A (en) * 2005-06-07 2008-07-16 爱德华兹生命科学公司 Systems and methods for assembling components of a fabric-covered prosthetic heart valve
CN104918582A (en) * 2012-12-19 2015-09-16 W.L.戈尔及同仁股份有限公司 Planar zone in prosthetic heart valve leaflet
CN106726008A (en) * 2017-01-04 2017-05-31 周诚 A kind of valve and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109893299A (en) * 2019-04-15 2019-06-18 杭州嘉和众邦生物科技有限公司 A kind of intervention pulmonary valve and its manufacturing method

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Publication number Publication date
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Address before: 430000 1277 Liberation Road, Wuhan, Hubei

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Applicant before: Shang Xiaoke

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