CN107308485A - 水凝胶泡沫复合材料及其生产工艺 - Google Patents

水凝胶泡沫复合材料及其生产工艺 Download PDF

Info

Publication number
CN107308485A
CN107308485A CN201710572579.2A CN201710572579A CN107308485A CN 107308485 A CN107308485 A CN 107308485A CN 201710572579 A CN201710572579 A CN 201710572579A CN 107308485 A CN107308485 A CN 107308485A
Authority
CN
China
Prior art keywords
hydrogel
foam
medical
production technology
foam composite
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710572579.2A
Other languages
English (en)
Inventor
古元安
刁建国
潘大庆
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beijing Health Guangji Biotechnology Co Ltd
Original Assignee
Beijing Health Guangji Biotechnology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beijing Health Guangji Biotechnology Co Ltd filed Critical Beijing Health Guangji Biotechnology Co Ltd
Priority to CN201710572579.2A priority Critical patent/CN107308485A/zh
Publication of CN107308485A publication Critical patent/CN107308485A/zh
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/60Liquid-swellable gel-forming materials, e.g. super-absorbents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/24Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/26Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28Polysaccharides or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/44Medicaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/46Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406Antibiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/41Anti-inflammatory agents, e.g. NSAIDs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Materials For Medical Uses (AREA)

Abstract

本发明涉及一种水凝胶泡沫复合材料及其生产工艺,属于医用材料的技术领域。本发明的水凝胶泡沫复合材料包括医用泡沫芯材以及形成在所述医用泡沫芯材外表面上的水凝胶层,所述水凝胶层外表面包覆有疏水性纱布或者所述医用泡沫芯材表面包覆有疏水性纱布。所述生产工艺通过在医用泡沫表面采用涂布、浸渍或喷涂的方式施加水凝胶溶液,采用沥干或压辊的方式除去未被泡沫吸收的水凝胶溶液,然后固化形成水凝胶层。本发明的水凝胶泡沫复合材料可作为卫生面条或伤口敷料使用。

Description

水凝胶泡沫复合材料及其生产工艺
技术领域
本发明属于医用材料的技术领域,更具体地说,本发明涉及一种水凝胶泡沫复合材料及其生产工艺。
背景技术
在现有技术中,无菌卫生棉条具有广泛的用途,例如可以制成常用的医用脱脂棉、一次使用的卫生用品、女性经期使用的卫生护垫以及阴道内置苗条等。目前,市场上销售的无菌卫生棉条通常采用压缩棉制成,其吸液量较低,而且由于阴道存在褶皱,使用压缩棉会有棉絮残留的情况发生。
发明内容
为了克服现有技术中存在的上述技术问题,本发明的目的在于提供一种水凝胶泡沫复合材料及其生产工艺。
为了解决实现发明目的,本发明的第一方面采用了以下技术方案:
一种水凝胶泡沫复合材料,其特征在于:包括医用泡沫芯材以及形成在所述医用泡沫芯材外表面上的水凝胶层。
其中,所述水凝胶层外表面包覆有疏水性纱布或者所述医用泡沫芯材表面包覆有疏水性纱布。
其中,所述医用泡沫芯材选自亲水性聚氨酯泡沫、疏水性聚氨酯泡沫、亲水性聚乙烯醇泡沫或亲水性壳聚糖泡沫中的一种。
其中,所述医用泡沫芯材的形状为棒状或片状。
其中,所述水凝胶层中载有抑菌剂、抗生素或消炎剂等中的至少一种添加剂,所述添加剂选自壳聚糖、蚁酸、醋酸、头孢羟氨苄、头孢唑啉、头孢克洛、头孢西丁、妥布霉素、庆大霉素、青霉素类、苯唑西林、磺胺类或甲硝唑中的一种或多种。
本发明的第二方面还涉及水凝胶泡沫复合材料的生产工艺。
本发明所述的生产工艺包括以下步骤:
(1)准备水凝胶溶液;
(2)在医用泡沫表面采用涂布、浸渍或喷涂的方式施加水凝胶溶液,采用沥干或压辊的方式除去未被泡沫吸收的水凝胶溶液,然后固化、裁剪、包装。
其中,在步骤(2)中被泡沫吸收的水凝胶溶液通过光照、辐照或加热的方式固化形成水凝胶层。
其中,在施加水凝胶溶液之前所述医用泡沫表面包覆有疏水性纱布。
其中,在形成水凝胶层之后包覆疏水性纱布。
其中,所述水凝胶溶液中添加有有抑菌剂、抗生素或消炎剂等中的至少一种添加剂,所述添加剂选自壳聚糖、蚁酸、醋酸、头孢羟氨苄、头孢唑啉、头孢克洛、头孢西丁、妥布霉素、庆大霉素、青霉素类、苯唑西林、磺胺类或甲硝唑中的一种或多种。
与现有技术相比,本发明的生产工艺得到的水凝胶泡沫复合材料具有以下有益效果:
①制备得到的复合材料作为卫生棉条使用可以提高吸液量,降低更换频率,而且能够避免因阴道存在褶皱而导致的棉絮残留问题。
②本发明的复合材料还可以作为伤口敷料,能够快速吸收伤口渗出液,创造有利于伤口愈合的环境。
具体实施方式
以下将结合具体实施例对本发明的水凝胶泡沫复合材料及其生产工艺做进一步的阐述,以帮助本领域的技术人员对本发明的发明构思、技术方案有更完整、准确和深入的理解。
本发明涉及一种水凝胶泡沫复合材料的生产工艺,其包括以下工艺步骤:
首先,配置水凝胶溶液,并且根据实际用途在其中可添加有所需的添加剂,例如选自抑菌剂、抗生素或消炎剂等中的至少一种添加剂,所述添加剂常用的有壳聚糖、蚁酸、醋酸、头孢羟氨苄、头孢唑啉、头孢克洛、头孢西丁、妥布霉素、庆大霉素、青霉素类、苯唑西林、磺胺类或甲硝唑等。
其次,准备医用泡沫,所述医用泡沫可通过在树脂原料中添加发泡剂然后通过发泡工艺制备得到。具体到医用领域,所述医用泡沫可以选择亲水性聚氨酯泡沫、疏水性聚氨酯泡沫、亲水性聚乙烯醇泡沫或亲水性壳聚糖泡沫中的一种。医用泡沫根据最终的用途可以预先裁切,卷成条状;或者采用片状的形式;并且也可以预先在其上包覆疏水性纱布。
然后,在准备好的医用泡沫表面采用涂布、浸渍或喷涂的方式施加水凝胶溶液,采用沥干或压辊的方式除去未被泡沫吸收的水凝胶溶液;并通过光照、辐照或加热的方式固化形成水凝胶层。
本发明的生产工艺制备的水凝胶泡沫复合材料具有吸液速度快、吸液量大的优点,可以用于一次性使用卫生用品(例如卫生面条)或伤口敷料、伤口填料等。
实施例1
准备添加有抑菌剂、抗生素或消炎剂的水凝胶溶液;在片状的医用泡沫表面采用涂布、浸渍或喷涂的方式施加所述水凝胶溶液,经过沥干或压辊的方式除去未被泡沫吸收的水凝胶溶液,再经过光照、辐照或加热的方式固化在医用泡沫材料表面形成添加有添加剂的水凝胶层;然后经过裁切,卷成条状,以卫生纱布包覆得到卫生面条,包覆的纱布可以防止水凝胶吸液后破碎残留在阴道内。
实施例2
准备添加有抑菌剂、抗生素或消炎剂的水凝胶溶液;在医用泡沫材料表面首先包覆疏水性的卫生纱布;采用涂布、浸渍或喷涂的方式施加所述水凝胶溶液,经过沥干或压辊的方式除去未被泡沫吸收的水凝胶溶液,再经过光照、辐照或加热的方式固化形成添加有添加剂的水凝胶层;然后裁切,压制成卫生棉条。
实施例3
准备添加有抑菌剂、抗生素或消炎剂的水凝胶溶液;医用泡沫先裁切卷成条状,在条状的医用泡沫表面采用涂布、浸渍或喷涂的方式施加所述水凝胶溶液,经过沥干或压辊的方式除去未被泡沫吸收的水凝胶溶液;再经过光照、辐照或加热的方式固化形成添加有添加剂的水凝胶层制备得到卫生棉条。
实施例4
准备添加有抑菌剂、抗生素或消炎剂的水凝胶溶液;准备各种不同形状的应用泡沫,并用细丝穿在一起,然后浸入所述水凝胶溶液中一段时间然后取出,并经过光照、辐照或加热的方式固化形成添加有添加剂的水凝胶层。这样得到的水凝胶复合材料可以不限制产品体积,可以用于人体任意腔体中(例如耳蜗、鼻孔等的止血或治疗)或用于伤口的敷料或填料。
对于本领域的普通技术人员而言,具体实施例只是对本发明进行了示例性描述,显然本发明具体实现并不受上述方式的限制,只要采用了本发明的方法构思和技术方案进行的各种非实质性的改进,或未经改进将本发明的构思和技术方案直接应用于其它场合的,均在本发明的保护范围之内。

Claims (10)

1.一种水凝胶泡沫复合材料,其特征在于:包括医用泡沫芯材以及形成在所述医用泡沫芯材外表面上的水凝胶层。
2.根据权利要求1所述的水凝胶泡沫复合材料,其特征在于:所述水凝胶层外表面包覆有疏水性纱布或者所述医用泡沫芯材表面包覆有疏水性纱布。
3.根据权利要求1所述的水凝胶泡沫复合材料,其特征在于:所述医用泡沫芯材选自亲水性聚氨酯泡沫、疏水性聚氨酯泡沫、亲水性聚乙烯醇泡沫或亲水性壳聚糖泡沫中的一种。
4.根据权利要求1所述的水凝胶泡沫复合材料,其特征在于:所述医用泡沫芯材的形状为棒状或片状。
5.根据权利要求1所述的水凝胶泡沫复合材料,其特征在于:所述水凝胶层中载有抑菌剂、抗生素或消炎剂等中的至少一种添加剂;所述添加剂选自壳聚糖、蚁酸、醋酸、头孢羟氨苄、头孢唑啉、头孢克洛、头孢西丁、妥布霉素、庆大霉素、青霉素类、苯唑西林、磺胺类或甲硝唑中的一种或多种。
6.一种水凝胶泡沫复合材料的生产工艺,其特征在于包括以下步骤:
(1)准备水凝胶溶液;
(2)在医用泡沫表面采用涂布、浸渍或喷涂的方式施加水凝胶溶液,采用沥干或压辊的方式除去未被泡沫吸收的水凝胶溶液,然后固化、裁剪、包装。
7.根据权利要求6所述的水凝胶泡沫复合材料的生产工艺,其特征在于:在步骤(2)中被泡沫吸收的水凝胶溶液通过光照、辐照或加热的方式固化形成水凝胶层。
8.根据权利要求6所述的水凝胶泡沫复合材料的生产工艺,其特征在于:在施加水凝胶溶液之前所述医用泡沫表面包覆有疏水性纱布。
9.根据权利要求6所述的水凝胶泡沫复合材料的生产工艺,其特征在于:在形成水凝胶层之后包覆疏水性纱布。
10.根据权利要求6所述的水凝胶泡沫复合材料的生产工艺,其特征在于:所述水凝胶溶液中添加有有抑菌剂、抗生素或消炎剂等中的至少一种添加剂,所述添加剂选自壳聚糖、蚁酸、醋酸、头孢羟氨苄、头孢唑啉、头孢克洛、头孢西丁、妥布霉素、庆大霉素、青霉素类、苯唑西林、磺胺类或甲硝唑中的一种或多种。
CN201710572579.2A 2017-07-13 2017-07-13 水凝胶泡沫复合材料及其生产工艺 Pending CN107308485A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710572579.2A CN107308485A (zh) 2017-07-13 2017-07-13 水凝胶泡沫复合材料及其生产工艺

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710572579.2A CN107308485A (zh) 2017-07-13 2017-07-13 水凝胶泡沫复合材料及其生产工艺

Publications (1)

Publication Number Publication Date
CN107308485A true CN107308485A (zh) 2017-11-03

Family

ID=60177953

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201710572579.2A Pending CN107308485A (zh) 2017-07-13 2017-07-13 水凝胶泡沫复合材料及其生产工艺

Country Status (1)

Country Link
CN (1) CN107308485A (zh)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109316621A (zh) * 2018-10-15 2019-02-12 苏州汇涵医用科技发展有限公司 一种水凝胶敷料的制备方法
CN109435345A (zh) * 2018-10-22 2019-03-08 南京纳铠生物医药科技有限公司 多层结构的红外隐身材料
CN113616425A (zh) * 2021-07-06 2021-11-09 蓝燕娜 水凝胶医用泡沫复合材料胶层成型系统及其成型方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN204671391U (zh) * 2015-05-18 2015-09-30 广东泰宝医疗科技股份有限公司 一种水凝胶泡沫敷料
WO2016038109A1 (en) * 2014-09-11 2016-03-17 Mölnlycke Health Care Ab Medical dressing
CN105662715A (zh) * 2016-04-07 2016-06-15 深圳普门科技有限公司 一种水凝胶泡沫敷料及其制备方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016038109A1 (en) * 2014-09-11 2016-03-17 Mölnlycke Health Care Ab Medical dressing
CN204671391U (zh) * 2015-05-18 2015-09-30 广东泰宝医疗科技股份有限公司 一种水凝胶泡沫敷料
CN105662715A (zh) * 2016-04-07 2016-06-15 深圳普门科技有限公司 一种水凝胶泡沫敷料及其制备方法

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109316621A (zh) * 2018-10-15 2019-02-12 苏州汇涵医用科技发展有限公司 一种水凝胶敷料的制备方法
CN109435345A (zh) * 2018-10-22 2019-03-08 南京纳铠生物医药科技有限公司 多层结构的红外隐身材料
CN113616425A (zh) * 2021-07-06 2021-11-09 蓝燕娜 水凝胶医用泡沫复合材料胶层成型系统及其成型方法

Similar Documents

Publication Publication Date Title
CN107308485A (zh) 水凝胶泡沫复合材料及其生产工艺
CN103405483B (zh) 一种口腔溃疡膜
CN103751833B (zh) 一种医用抗菌创伤敷料及其制备方法
US20170197006A1 (en) Honey-based foam compositions
CN105999365A (zh) 一种功效型鼻腔止血材料及其制备方法
CN105434107A (zh) 硅凝胶负压封闭引流敷料
CN103480032B (zh) 一种含银复合凝胶敷料及其制备方法
CN203591383U (zh) 伤口覆盖物
US20160158403A1 (en) A wound dressing
US20180338867A1 (en) Resorbable preparation for medical applications, and characteristic uses for said preparation
CN206792706U (zh) 一种外用止血敷料
CN201346260Y (zh) 止血海绵护创贴
CN204521196U (zh) 强效型创可贴
CN205339304U (zh) 硅凝胶负压封闭引流敷料
CN103520765B (zh) 一种创伤止血敷料的制备方法
CN206334017U (zh) 一种锥形肛肠科填塞敷料
CN202654310U (zh) 无菌透气防水敷料
CN202761355U (zh) 一种止血鼻塞
CN204521872U (zh) 一种呼吸机鼻塞
CN219184534U (zh) 一种新型大孔聚氨酯泡沫敷料
CN205198266U (zh) 一种透气型创口贴
CN108992699A (zh) 一种含活性复合材料的功能性创面敷料及其制备方法
CN204050030U (zh) 痔瘘专用敷贴
CN209075170U (zh) 一种新型吸收物品
CN203988649U (zh) 一种银离子藻酸盐复合敷料

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
DD01 Delivery of document by public notice

Addressee: UNION MEDICAL SUPPLIES Co.,Ltd.

Document name: Decision of Rejection

DD01 Delivery of document by public notice
RJ01 Rejection of invention patent application after publication

Application publication date: 20171103

RJ01 Rejection of invention patent application after publication