CN107300745A - A kind of chip clamping and flow control apparatus suitable for a variety of prisms - Google Patents

A kind of chip clamping and flow control apparatus suitable for a variety of prisms Download PDF

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Publication number
CN107300745A
CN107300745A CN201710721617.6A CN201710721617A CN107300745A CN 107300745 A CN107300745 A CN 107300745A CN 201710721617 A CN201710721617 A CN 201710721617A CN 107300745 A CN107300745 A CN 107300745A
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CN
China
Prior art keywords
prism
control apparatus
flow control
variety
clamping
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Granted
Application number
CN201710721617.6A
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Chinese (zh)
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CN107300745B (en
Inventor
张蓓
荆嘉伟
刘雨
闫鹏
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Beihang University
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Beihang University
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    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B7/00Mountings, adjusting means, or light-tight connections, for optical elements
    • G02B7/18Mountings, adjusting means, or light-tight connections, for optical elements for prisms; for mirrors
    • G02B7/1805Mountings, adjusting means, or light-tight connections, for optical elements for prisms; for mirrors for prisms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55Specular reflectivity
    • G01N21/552Attenuated total reflection
    • G01N21/553Attenuated total reflection and using surface plasmons
    • G01N21/554Attenuated total reflection and using surface plasmons detecting the surface plasmon resonance of nanostructured metals, e.g. localised surface plasmon resonance

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  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Nanotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

The present invention proposes a kind of chip clamping suitable for a variety of prisms and flow control apparatus, belongs to nanometer detection and photoelectric sensing field.The present invention is made up of three parts, is device pedestal, prism clamping device and fluid storage device respectively.Wherein there are screwed hole and counterbore on base.Base is used for fixed prism clamping device and whole device is fixed on into third-party platform.Prism clamping device is L-type framework, its bottom through-hole is used for and base is fixed, its vertical plane is used on fixed prism and fluid storage device, prism clamping device vertical plane equilateral prism support and right-angle prism support can be used to be respectively used to fix equilateral prism and right-angle prism.Fluid storage device is rectangular block, and there is the groove for storing liquid at the center of rectangular block one side, while liquid can pass through the screwed hole inflow and outflow groove on rectangular block.

Description

A kind of chip clamping and flow control apparatus suitable for a variety of prisms
Technical field
The present invention relates to a kind of chip clamping suitable for a variety of prisms and flow control apparatus, belong to nanometer detection and photoelectric transfer Sense field.
Background of invention
Surface plasma body resonant vibration (Surface Plasmon Resonance, SPR) sensing technology is a kind of new light Electro-detection technology, is widely used in biologic medical field.Kretchmann proposes the micro- system of surface plasma of lens type System, its system proposed early stage is widely used in the detection of solid sample, and current biological, medical science, environment, chemistry etc. for The detection demand of liquid phase sample is very big, and liquid phase sample lacks effective liquid storage and chip clamping device in detection.
In the detection process of liquid phase sample, liquid needs are more uniform to be distributed in censorchip surface, and device needs Inflow and outflow and its flow velocity of liquid can be controlled.There is micro-fluidic function can fix print simultaneously and liquid is not flowed for research and development Lose necessary.The present invention propose one kind can effectively clamp prism and chip and effectively storage liquid phase sample while not Damage the chip that can be suitably used for a variety of prisms clamping and the flow control apparatus of chip structure.
The content of the invention
(1) technical problem to be solved
The detection of current liquid phase sample demand in biological, chemistry is very big, and lens type system is applied to liquid phase and detected extremely Extensively, but liquid is easier to be lost in prism surface, the clamping of effective sensing chip and fluid control device are lacked.
(2) solution
The invention provides a kind of chip clamping suitable for a variety of prisms and flow control apparatus, energy while fixed prism Enough fix sensing chip and liquid can be stored in chip surface and the inflow and outflow of liquid is controlled, in liquid detecting field tool Have wide application prospects.
A kind of chip clamping and flow control apparatus suitable for a variety of prisms, including:Device pedestal, prism fixing device and stream Control the part of device three.
Device pedestal is the counterbore for having multiple screwed holes and multiple different sizes on cylindrical structure, base, and base, which rises, to be turned Effect is connect, prism fixing device can be fixed in optical system, screwed hole is used for and prism fixing device connection, counterbore is used In firm banking.
Prism fixing device includes L-shaped framework and prism fixed mount, and the bottom surface of L-shaped framework has four through holes to be used for and base One coffin of vacancy in the middle of connection, the vertical plane of L-shaped framework, flow control apparatus can be embedded in the coffin of vacancy.L-shaped structure Frame vertical plane empty portions edge has four screwed holes to be used to fix flow control apparatus;Another vertical plane of L-shaped framework have above and below two Each four screwed holes are arranged, two row's screwed holes are used for and prism fixed mount coordinates with fixed prism.Prism fixed mount has right-angle prism Frame and equilateral prism frame, right-angled edge mirror holder are used to fix right-angle prism, and right-angled edge mirror holder is 90 degree of components, and member end has two Individual through hole is used to coordinate with the screwed hole for often arranging screwed hole two ends on L-shaped framework vertical plane.Equilateral prism frame is used to fix equilateral Prism, equilateral prism frame is 60 degree of components, member end have two through holes be used for and L-shaped framework vertical plane on often arrange screwed hole Centre two screwed holes coordinate.
Flow control apparatus center section is rectangular block, and one side of rectangular block is outstanding close to four angle parts, and four are dashed forward Going out has through hole on part, four screwed holes on four through holes and L-shaped framework vertical plane coordinate to fix flow control apparatus.Rectangle Block one side has the circular groove of indent, and the radius and sensing chip radius of circular groove are close, comprising two half-thread through holes in circular groove, and half Two sides of tapped through hole connection rectangular block are used for the inflow and outflow for controlling liquid.
During assembling, four through holes of base for the L-shaped framework that screw passes through prism fixing device are connected the four of base In individual screw.Prism is fixed on the vertical plane of L-shaped framework by two prism fixed mounts, and flow control apparatus passes through its projection Four through holes are fixed on the vertical plane of L-shaped framework, and a rounded washers are placed at the indent circular groove edge of flow control apparatus, sense core Piece one side is in contact with packing ring, and another side is directly contacted with prism.
Brief description of the drawings
Fig. 1 is the base schematic diagram a kind of chip clamping suitable for a variety of prisms and flow control apparatus;
Fig. 2 is surveyed for oblique two of prism fixing device a kind of chip clamping suitable for a variety of prisms and flow control apparatus and regarded Figure;
Fig. 3 is a kind of front view of prism fixing device chip clamping suitable for a variety of prisms and flow control apparatus;
Fig. 4 is right-angle prism support and equilateral prism branch a kind of chip clamping suitable for a variety of prisms and flow control apparatus The structural representation of frame;
Fig. 5 is the flow control apparatus schematic diagram a kind of chip clamping suitable for a variety of prisms and flow control apparatus;
Fig. 6 is that a kind of chip clamping suitable for a variety of prisms and flow control apparatus assemble right-angle prism and equilateral prism respectively Overall schematic;
In wherein Fig. 1:101:Screwed hole;102:Through hole;
In Fig. 2:201:Counterbore;202:Screwed hole;203:Rectangle vacancy;
In Fig. 3:204:Screwed hole;205:Screw thread;
In Fig. 4:206:Right-angle prism support;207 equilateral prism supports;
In Fig. 5:301:Through hole;302:Screwed hole;303 circular grooves;
In Fig. 6:1:Clamping device base;2:Prism fixing device;3:Flow control apparatus;4:Right-angle prism;5:Equilateral prism.
Embodiment
With reference to the accompanying drawings and examples, the embodiment to the present invention is described in further detail.Following instance For illustrating the present invention, but it is not limited to the scope of the present invention.
In the description of the invention, it is necessary to explanation, term " " center ", " longitudinal direction ", " transverse direction ", " on ", " under ", The orientation or position relationship of the instruction such as "front", "rear", "left", "right", " vertical ", " level ", " top ", " bottom " " interior ", " outer " are Based on orientation shown in the drawings or position relationship, it is for only for ease of the description present invention and simplifies description, rather than indicate or dark Specific orientation must be had, with specific azimuth configuration and operation by showing the device or element of meaning, therefore it is not intended that right The limitation of the present invention.
In the description of the invention, it is necessary to illustrate, unless otherwise clearly defined and limited, term " installation ", " phase Even ", " connection " should be interpreted broadly, for example, it may be being fixedly connected or being detachably connected, or be integrally connected;Can To be mechanical connection or electrical connection;Can be joined directly together, can also be indirectly connected to by intermediary, Ke Yishi The connection of two element internals.For the ordinary skill in the art, with concrete condition above-mentioned term can be understood at this Concrete meaning in invention.
Embodiment one:
As Figure 1-5, the invention provides a kind of chip clamping suitable for a variety of prisms and flow control apparatus, it includes Clamping device base 1, prism fixing device 2 and the flow control apparatus 3 being connected successively, the flow control apparatus 3 are solid positioned at prism Determine in device 2;
As shown in figure 1, having four screwed holes 101 and six through holes 102 on base, screwed hole 101 is solid for fixed prism Determine device 2, through hole 102 can be such that through hole is fixed on other devices;
As Figure 2-Figure 5, four through holes 201 on the bottom of prism fixing device 2 are used for and four screw threads on base Hole 101 coordinates with fixed prism fixing device 2.Rectangle vacancy 203 is used to place flow control apparatus on the vertical plane of prism fixing device 2 3, four screwed holes 202 on the vertical plane of prism fixing device 2 are used to fix flow control apparatus 3.As shown in figure 3, prism fixes dress Putting the another side of 2 vertical planes has two rows screwed hole, and often row has screwed hole four, wherein two screwed holes per exclusive side 204 are used to fix right-angle prism support 206.
As shown in figure 5, there is four through holes on the edge projection 301 of flow control apparatus 3, four through holes 301 and prism are solid Determine four on device 2 screwed holes 202 and be engaged there are two screwed holes 302 on flow control apparatus, flow control apparatus one side to fix For controlling have circular groove 303 on flowing in and out for liquid, the another side of flow control apparatus, the edge of circular groove 303 is put Put and place sensing chip on a rounded washers and then packing ring.Chip-side is close to packing ring, when liquid flow membership is stored in stream control In device cup washer and the closing space of sensing chip formation, the opposite side of chip is close to prism.
As shown in left side in Fig. 6, two right-angle prism supports 206 can be used to fix right-angle prism 4.
Embodiment two:
On the basis of embodiment one, when assembling equilateral prism 5, equilateral prism 5 is placed on prism and consolidated Determine on device vertical plane, reuse equilateral prism support 207 to fix equilateral prism 5, equilateral prism support 207 is fixed on screw thread On hole 205, assembling result is as shown in right side in Fig. 6.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention God is with principle, and any modification, equivalent substitution and improvements made etc. should be included in the scope of the protection.

Claims (5)

1. a kind of chip clamping and flow control apparatus suitable for a variety of prisms, it is characterised in that:Including clamping device base, prism There are screwed hole and counterbore on clamping device and fluid storage device, wherein base, base is used for fixed prism clamping device and will Whole device is fixed on third-party platform;Prism clamping device is L-type framework, and its bottom through-hole is used for and base is fixed, its Vertical plane is used to that equilateral prism support can be used on fixed prism and fluid storage device, prism clamping device vertical plane and straight Angle prism support is respectively used to fix equilateral prism and right-angle prism;During fluid storage device is rectangular block, rectangular block one side The heart, which has in the middle of circular groove, circular groove, two half-thread through holes, and groove is used to store liquid, and liquid passes through two through hole streams Enter groove, chip is close to groove and prism surface during cooperation.
2. a kind of chip clamping and flow control apparatus suitable for a variety of prisms according to claim 1, it is characterised in that:Institute The screwed hole for having fixed equilateral prism and right-angle prism support on prism fixing device vertical plane is stated, the distribution of screwed hole is on this The vertical bisector of vertical plane is symmetrical.
3. a kind of chip clamping and flow control apparatus suitable for a variety of prisms according to claim 1, it is characterised in that:Institute Rectangle flow control apparatus can be embedded in by stating on the vertical plane of L-shaped prism fixing device.
4. a kind of chip clamping and flow control apparatus suitable for a variety of prisms according to claim 1, it is characterised in that:Institute The flow control apparatus circular groove radius stated is more than or equal to the radius of print, and recess edge places one layer of packing ring, packing ring during assembling Upper chip placement.
5. a kind of chip clamping and flow control apparatus suitable for a variety of prisms according to claim 1, it is characterised in that:Institute The prism fixing device stated can fix two kinds of prisms of equilateral prism and right-angle prism.
CN201710721617.6A 2017-08-22 2017-08-22 A kind of chip clamping and flow control apparatus suitable for a variety of prisms Expired - Fee Related CN107300745B (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111103671A (en) * 2020-01-13 2020-05-05 吉林工程技术师范学院 Beam splitting prism assembly for off-axis three-mirror optical system and operation method thereof
CN112824967A (en) * 2019-11-19 2021-05-21 青岛海信激光显示股份有限公司 Laser projection device
CN113534400A (en) * 2021-06-29 2021-10-22 西安航天精密机电研究所 Prism assembly and assembling method thereof
US11630378B2 (en) 2019-11-19 2023-04-18 Hisense Laser Display Co., Ltd. Laser projection apparatus

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EP1684063A1 (en) * 2005-01-19 2006-07-26 Samsung Electronics Co.,Ltd. Portable biochip scanner using surface plasmon resonance
CN1811582A (en) * 2005-01-28 2006-08-02 台达电子工业股份有限公司 Optical assembly device and assembling method
CN101251483A (en) * 2008-01-11 2008-08-27 北京赛德创生物技术有限公司 Test analytical instrument using surface plasma resonance oscillation detection technique
CN103675053A (en) * 2013-09-27 2014-03-26 中国科学院电子学研究所 Local electrochemical imaging test system based on surface plasma resonance
US20160266111A1 (en) * 2013-10-31 2016-09-15 Konica Minolta, Inc. Detection Device, Detection Method Using Said Detection Device, And Detection Chip Used In Said Detection Device
CN106501219A (en) * 2016-10-19 2017-03-15 中国科学院电子学研究所 A kind of Portable, multiple parameter surface plasma resonance biochemical analyzer

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1684063A1 (en) * 2005-01-19 2006-07-26 Samsung Electronics Co.,Ltd. Portable biochip scanner using surface plasmon resonance
CN1811582A (en) * 2005-01-28 2006-08-02 台达电子工业股份有限公司 Optical assembly device and assembling method
CN101251483A (en) * 2008-01-11 2008-08-27 北京赛德创生物技术有限公司 Test analytical instrument using surface plasma resonance oscillation detection technique
CN103675053A (en) * 2013-09-27 2014-03-26 中国科学院电子学研究所 Local electrochemical imaging test system based on surface plasma resonance
US20160266111A1 (en) * 2013-10-31 2016-09-15 Konica Minolta, Inc. Detection Device, Detection Method Using Said Detection Device, And Detection Chip Used In Said Detection Device
CN106501219A (en) * 2016-10-19 2017-03-15 中国科学院电子学研究所 A kind of Portable, multiple parameter surface plasma resonance biochemical analyzer

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112824967A (en) * 2019-11-19 2021-05-21 青岛海信激光显示股份有限公司 Laser projection device
US11630378B2 (en) 2019-11-19 2023-04-18 Hisense Laser Display Co., Ltd. Laser projection apparatus
CN111103671A (en) * 2020-01-13 2020-05-05 吉林工程技术师范学院 Beam splitting prism assembly for off-axis three-mirror optical system and operation method thereof
CN111103671B (en) * 2020-01-13 2022-06-07 吉林工程技术师范学院 Beam splitting prism assembly for off-axis three-mirror optical system and operation method thereof
CN113534400A (en) * 2021-06-29 2021-10-22 西安航天精密机电研究所 Prism assembly and assembling method thereof
CN113534400B (en) * 2021-06-29 2023-03-14 西安航天精密机电研究所 Prism assembly and assembling method thereof

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