CN107290560B - Reagent sucking method and device for multi-bottle reagent and sample analyzer - Google Patents
Reagent sucking method and device for multi-bottle reagent and sample analyzer Download PDFInfo
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- CN107290560B CN107290560B CN201610205694.1A CN201610205694A CN107290560B CN 107290560 B CN107290560 B CN 107290560B CN 201610205694 A CN201610205694 A CN 201610205694A CN 107290560 B CN107290560 B CN 107290560B
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1011—Control of the position or alignment of the transfer device
Abstract
A reagent pipetting method, apparatus and sample analyzer for multiple vials of reagent, the method comprising: acquiring a suction order of a plurality of bottles of reagents and a placing position of the plurality of bottles of reagents set by a user, determining a priority sequence of reagent positions for executing reagent suction operation according to the placing position of the plurality of bottles of reagents and the suction order of the plurality of bottles of reagents, determining relative displacement of a suction mechanism and a reagent bearing mechanism at least according to the priority sequence, and driving the suction mechanism and/or the reagent bearing mechanism to move according to the relative displacement of the suction mechanism and the reagent bearing mechanism; controlling the sucking and injecting mechanism to execute reagent sucking operation. Because the priority sequence of the reagent positions for executing reagent sucking operation is determined according to the sucking sequence of a plurality of bottles of reagents set by a user, and the relative displacement of the sucking and injecting mechanism and the reagent bearing mechanism is determined at least according to the priority sequence, the reagent expected by the user is transferred to the reagent sucking positions, and finally the reagent is sucked according to the sequence set by the user.
Description
Technical Field
The invention relates to a sample analyzer, in particular to a reagent sucking method and a reagent sucking device of the sample analyzer.
Background
The full-automatic sample analyzer is used for analyzing samples from a tested body and is characterized by high automation degree and high testing speed. In some hospitals, some items have a large daily test quantity, so the quantity of various reagents used in the test items is also large, and in order to ensure the continuity of the test, doctors usually place multiple bottles (hereinafter referred to as multiple bottles) on the instrument for the same reagent, and the instrument software determines which bottle of reagent is sucked in advance through a default sucking order. For example, three bottles of the same reagent are placed on the reagent tray, and the instrument software defaults that the reagent is sucked in the order of small to large cup coordinates.
In view of the differences in the reagent storage and dispensing operations at each hospital, a doctor may choose an overdue reagent or calibrate an overdue reagent during the reagent dispensing process. In such a case, the physician will typically wish to administer the overdue reagent first, or the calibration parameters will be overdue first. In the manner in which the instrument software autonomously determines the aspiration sequence, the physician does not have sufficient authority to select the reagent aspiration sequence, which may result in the physician wasting more expensive reagents or performing more complex calibration procedures.
Disclosure of Invention
The application provides a reagent suction method and device for a plurality of bottles of reagents and a sample analyzer, which can enable a user to set the suction sequence of the plurality of bottles of reagents by himself.
According to a first aspect, there is provided in one embodiment a reagent pipetting method for multiple vials of reagent, comprising:
acquiring a suction order of a plurality of bottles of reagents and a placement position of the plurality of bottles of reagents, wherein the plurality of bottles of reagents are contained in a plurality of containers and belong to the same type;
determining the priority sequence of reagent positions for executing reagent sucking operation according to the placing positions of the plurality of bottles of reagents and the sucking sequence of the plurality of bottles of reagents;
determining the relative displacement of the sucking and injecting mechanism and the reagent bearing mechanism at least according to the priority sequence;
in the reagent sucking link, the sucking and injecting mechanism and/or the reagent bearing mechanism are driven to move according to the relative displacement of the sucking and injecting mechanism and the reagent bearing mechanism;
controlling the sucking and injecting mechanism to execute reagent sucking operation.
According to a second aspect, there is provided in an embodiment a reagent pipetting control device for a multi-vial reagent comprising:
the information acquisition module is used for acquiring the suction sequence and the placement positions of a plurality of bottles of reagents set by a user, wherein the plurality of bottles of reagents are contained in a plurality of containers and belong to the same type;
the test module is used for determining the priority sequence of reagent positions for executing reagent sucking operation according to the placing positions of the plurality of bottles of reagents and the sucking sequence of the plurality of bottles of reagents, and determining the relative displacement of the sucking and injecting mechanism and the reagent bearing mechanism according to the priority sequence at least;
and the sucking and injecting module is used for driving the sucking and injecting mechanism and/or the reagent bearing mechanism to move according to the relative displacement of the sucking and injecting mechanism and the reagent bearing mechanism in a reagent sucking link and controlling the sucking and injecting mechanism to execute reagent sucking operation.
According to a third aspect, there is also provided a sample analyzer comprising:
the human-computer interaction equipment is used for providing an input/output interface and an input interface for a user;
the reagent carrying mechanism is used for carrying a reagent and is provided with a plurality of reagent positions for accommodating reagent containers;
the sucking and injecting mechanism is used for sucking the reagent from the reagent tray and injecting the sucked reagent into the reaction cup;
and the control system is electrically connected with the human-computer interaction equipment and performs data interaction with the human-computer interaction equipment, and the control system comprises the reagent suction control device.
In the embodiment of the invention, the priority sequence of the reagent positions for executing reagent sucking operation is determined according to the sucking sequence of a plurality of bottles of reagents set by a user, and the relative displacement of the sucking and injecting mechanism and the reagent bearing mechanism is determined at least according to the priority sequence, so that the reagents expected by the user are transferred to the reagent sucking positions, and finally the reagents are sucked according to the sequence set by the user.
Drawings
FIG. 1 is a schematic view of a portion of a sample analyzer;
FIG. 2 is a block diagram of a reagent uptake control device according to an embodiment;
FIG. 3 is a flow chart of reagent aspiration in accordance with one embodiment;
FIG. 4 is an interface for setting the reagent pipetting sequence upon test application;
FIG. 5 is a schematic diagram of the placement of multiple bottles of reagent on a reagent tray;
FIG. 6 is a flow chart of reagent aspiration in example two.
Detailed Description
The present invention will be described in further detail with reference to the following detailed description and accompanying drawings.
The first embodiment is as follows:
sample analyzers generally operate according to the following process: applying for testing, sample introduction, sample suction, reagent suction, reaction, and processing according to different analysis items after reaction. Referring to fig. 1, the sample analyzer includes a human-computer interaction device 1, a control system 3, a storage module 2 for storing data, a sample carrying mechanism, a reagent carrying mechanism, an aspiration and injection mechanism, and a reaction module, wherein the control system 3 is electrically connected to the human-computer interaction device 1, the storage module 2, the sample carrying mechanism, the reagent carrying mechanism, the aspiration and injection mechanism, and the reaction module through an interface module 4.
The human-computer interaction device 1 provides an input/output interface and an input device for a user (e.g., a doctor), receives information input by the user, and presents status parameters of the sample analyzer to the user. In one embodiment, the human-computer interaction device 10 includes a display, a keyboard and a mouse, and in another embodiment, the human-computer interaction device 10 may also be a display with a touch screen. In this embodiment, the user inputs the sample information, the test items of the sample, and the placement position of the sample on the sample support mechanism through the human-computer interaction device 10. In this embodiment, a user applies for a test through the human-computer interaction device 1, where the test application includes input sample information, reagent information, and test items.
The sucking and injecting mechanism is used for sucking the sample and the reagent and injecting the sucked sample and reagent into the reaction cup. As shown in fig. 1, the aspiration mechanism may include a sample aspiration mechanism 26 and a reagent aspiration mechanism 25. In some embodiments, the sample sucking and injecting mechanism and the reagent sucking and injecting mechanism may also share one sucking and injecting mechanism, that is, one sucking and injecting mechanism performs both the sample sucking and injecting operation and the reagent sucking and injecting operation, and the sampling needle of the sucking and injecting mechanism is cleaned after the sample sucking and injecting operation or the reagent sucking and injecting operation is performed each time. The suction and injection mechanism can perform suction and injection operation through up-and-down movement and rotation movement, and can also perform suction and injection operation through three-dimensional movement.
The reaction module is used for providing an incubation place for the sample and the reagent, in this embodiment, the reaction module includes a reaction tray 27, a plurality of placing positions 28 are arranged along the edge portion of the reaction tray 27, each placing position can accommodate one reaction cup, after the sample is sucked by the sample sucking and injecting mechanism 26, the sucked sample is injected into a predetermined reaction cup, after the reagent is sucked by the reagent sucking and injecting mechanism 25, the sucked reagent is also injected into the predetermined reaction cup, and the sample and the reagent are mixed uniformly in the reaction cup and incubated. In general, a sample injection site and a reagent injection site are set on the rotation trajectory of the reaction disk 27. In some embodiments, the reaction tray may also include a sample reagent injection site where both the sample and the reagent are injected into the reaction cup by the pipetting mechanism.
The sample bearing mechanism is used for bearing the sample and transferring the sample to a preset position, and the sample bearing mechanism is provided with a plurality of sample positions, and a container used for containing the sample is placed on each sample position. In one embodiment, as shown in fig. 1, the sample support mechanism is a sample tray 22, a plurality of sample sites 21 are disposed along an edge portion of the sample tray, the sample tray 22 can rotate to transfer the sample to the aspirate sample site, and the sample aspiration mechanism 26 performs the aspirate sample operation when the sample tray 22 transfers the sample to the aspirate sample site. In some embodiments, the sample carrier mechanism may also be a sample rack, and the sample on the sample rack is transported to the aspirating sample position by the transport mechanism. In some embodiments, the sample carrier can be fixed in a certain position, and the movement of the sample sucking and injecting mechanism 26 is controlled, so that the sampling needle of the sample sucking and injecting mechanism 26 moves to the sample sucking position.
The reagent carrying mechanism is used for carrying a reagent and transferring the reagent to a preset position, and the reagent carrying mechanism is provided with a plurality of reagent positions, and each reagent position is provided with a container for containing the reagent. In one embodiment, as shown in fig. 1, the reagent carrying mechanism is a reagent tray 23, a plurality of reagent sites 24 are disposed along an edge portion of the reagent tray, the reagent tray 23 can selectively transfer a reagent to a set reagent sucking site, and the reagent sucking and injecting mechanism 25 performs a reagent sucking operation when the reagent tray 23 transfers a reagent to a reagent sucking site. In some embodiments, the reagent carrying mechanism may be fixed at a certain position, and the reagent sucking and injecting mechanism is controlled to move, so that the sampling needle of the reagent sucking and injecting mechanism moves to the reagent sucking position.
The control system 3 is used for performing data interaction with the human-computer interaction device 1, receiving information input by a user from the human-computer interaction device 1, including a test application and a user instruction, and feeding back a test state and a test result of the analyzer to the human-computer interaction device 1. The control system 3 is also used to read data from the memory module 2 or to save data in the memory module 2. The control system 3 is also used for controlling the work of each part of the analyzer, in the sample sucking link, the control system 3 controls the sample disc 22 to transfer the sample to the sample sucking position, the sample sucking and injecting mechanism 26 is controlled to drive the sampling needle to move to the position above the sample sucking position, the sample sucking operation is executed on the sample placed on the sample sucking position, then the sample sucking and injecting mechanism 26 is controlled to drive the sampling needle to move to the position above the reaction disc, meanwhile, the reaction disc 27 is controlled to rotate, a preset reaction cup is rotated to the sample injecting position, and then the sampling needle injects the sucked sample into the reaction cup. In the reagent sucking link, the reagent disk 23 is controlled to transfer the reagent to the reagent sucking position, the reagent sucking and injecting mechanism 25 is controlled to drive the sampling needle to move to the position above the reagent sucking position, the reagent sucking operation is performed on the reagent placed on the reagent sucking position, then the reagent sucking and injecting mechanism 25 is controlled to drive the sampling needle to move to the position above the reaction disk, meanwhile, the reaction disk 27 is controlled to rotate, a preset reaction cup is rotated to the reagent injecting position, and then the sampling needle injects the sucked reagent into the reaction cup.
For a certain test item, the type of reagent used is determined, for example, one reagent or multiple reagents are needed in the test process, in this embodiment, multiple bottles may be prepared for the same type of reagent, and the control system 3 includes a reagent suction control device for sequencing multiple bottles of reagents and controlling reagent suction, as shown in fig. 2, the reagent suction control device includes an information acquisition module 31, a test module 32, a suction module 33, and a remaining amount management module 34. The information acquisition module 31 is configured to acquire a suction order of a plurality of bottles of reagents and a placement position of the plurality of bottles of reagents, where the plurality of bottles of reagents are contained in a plurality of containers and belong to the same type; the test module 32 is used for determining the priority sequence of the reagent positions for executing reagent sucking operation according to the placing positions of the plurality of bottles of reagents and the sucking sequence of the plurality of bottles of reagents, and determining the relative displacement of the sucking and injecting mechanism and the reagent bearing mechanism according to the priority sequence at least; the sucking and injecting module 33 is configured to drive the sucking and injecting mechanism and/or the reagent carrying mechanism to move according to the relative displacement of the sucking and injecting mechanism and the reagent carrying mechanism in the reagent sucking link, so that the active reagent is transferred to the set reagent sucking position, and the sucking and injecting mechanism is controlled to perform reagent sucking operation on the active reagent. The remaining amount management module 34 is configured to analyze and manage the remaining amount of the effective reagent after the reagent sucking operation, and determine whether to switch the reagent bottle according to an analysis result. In a specific embodiment, the test module 32 further includes an effective reagent determination unit 321 and a rotation planning unit 322, where the effective reagent determination unit 321 is configured to determine, according to a priority order, a reagent position on which a reagent sucking operation is to be performed, and to use a reagent placed on the reagent position as an effective reagent. When the test is started, the effective reagent determining unit 321 is configured to take the first-ranked reagent bit as the reagent bit for performing the reagent sucking operation according to the priority ranking, and when the reagent bottle needs to be switched according to the judgment of the remaining amount management module 34 during the test, the effective reagent determining unit 321 takes the next-ranked reagent bit as the reagent bit for performing the reagent sucking operation. The rotation planning unit 322 is used to plan the rotation of the reagent carrying mechanism, for example, to plan the rotation direction and the number of rotating cup positions of the reagent carrying mechanism, so that the effective reagent is transferred to the reagent sucking position.
For convenience of description, the present embodiment is described by taking the example that the test application only needs one type of reagent, and based on the above sample analyzer, when there are multiple bottles of reagent in the reagent of the type, the method for aspirating the reagent can be as shown in fig. 3, and includes the following steps:
And 110, after completing the test application, the user starts the test to obtain the placing positions of the reagents, for example, the reagent disk rotates to enable the reagents to pass through the information reading device in sequence, the information reading device reads the information of the reagents, and the placing positions of the reagents can be known according to the information of the reagents and the setting positions of the information reading device.
And 120, performing priority sorting according to the suction order. The information acquisition module acquires a suction sequence of a plurality of bottles of reagents and a placing position of the plurality of bottles of reagents set by a user, and the test module determines the priority sequence of reagent positions for executing reagent suction operation according to the placing position of the plurality of bottles of reagents and the suction sequence of the plurality of bottles of reagents. As shown in fig. 5, there are three bottles of the same reagent: reagent A, reagent B and reagent C, wherein the batch number of the reagent A is P0001, and the bottle number is B0001; the batch number of the reagent B is P0001, and the bottle number is B0002; the lot number of the reagent C is P0002, the bottle number is B0001, the sucking order of three bottles of reagents set by the user is shown in fig. 4, and the placing positions of the reagents are shown in fig. 5: reagent a is placed at the number 1 position 23a, reagent B is placed at the number 3 position 23B, and reagent C is placed at the number 4 position 23C, the priority of the reagent positions for performing the reagent sucking operation is: no. 3 position 23B, No. 1 position 23a, No. 4 position 23C, that is, reagent B on No. 3 position 23B is first sucked, reagent A on No. 1 position 23a is then sucked, and reagent C on No. 4 position 23C is finally sucked.
In step 130, the reagent disk rotation is planned. And according to the priority sequence, performing reagent sucking operation on the first reagent position, and planning the rotation action of the reagent disk, such as the rotation direction and the number of rotating cups of the reagent disk, according to the current position coordinate of the first reagent position and the set position coordinate of the reagent sucking position. For example, the reagent sucking operation is performed on the reagent No. B002 placed on the reagent No. 3 position 23B, and the reagent No. B002 is currently effective, so the reagent No. 3 position 23B is rotated to the reagent sucking position 24a first.
And 150, after the reagent disk rotates in place, controlling the sucking and injecting mechanism to suck and inject the reagent on the reagent sucking position by the sucking and injecting module.
The present embodiment allows a user to set the order of use of a plurality of bottles of reagents and finally determines the rotation of the reagent tray according to the order of use of the plurality of bottles of reagents, thereby making the order of aspiration of reagents meet the user's expectations.
Example two:
the difference between this embodiment and the first embodiment is that the reagent information input by the user on the test application interface further includes reagent usable times and cycle information, and the cycle information is used to specify whether multiple bottles of reagents are cyclically supplied with reagents. The flowchart of this embodiment is shown in fig. 6, and includes the following steps:
in step 200, a user inputs reagent information on a test application interface, wherein the reagent information comprises reagent absorption sequence information, testable times and circulation information, and the circulation information can be selected to be non-circulation or circulation.
And step 220, carrying out priority sorting according to the suction order. The specific steps may be the same as those in the first embodiment.
In step 230, the reagent disk rotation action is planned. The reagent disk rotation operation is planned according to the priority ranking and the circulation information, or the reagent disk rotation operation is planned according to the priority ranking, the suction frequency and the circulation information, for example, a reagent bottle A, a setting sequence 1, the suction frequency 2, a reagent bottle B, a setting sequence 2, the suction frequency 2, if the circulation information is not circulation, the suction sequence is as follows:
A->A->B->B
if the cycle information is a cycle, the order of aspiration is as follows:
A->B->A->B
And 250, after the reagent disk rotates to the position, the sucking and injecting module controls the sucking and injecting mechanism to suck the reagent on the reagent sucking position.
Those skilled in the art will appreciate that all or part of the steps of the methods in the above embodiments may be implemented by a program instructing relevant hardware to perform the steps, and the program may be stored in a computer-readable storage medium, and the storage medium may include: read-only memory, random access memory, magnetic or optical disk, and the like.
The present invention has been described in terms of specific examples, which are provided to aid understanding of the invention and are not intended to be limiting. For a person skilled in the art to which the invention pertains, several simple deductions, modifications or substitutions may be made according to the idea of the invention.
Claims (8)
1. A reagent pipetting method for multiple vials of reagent for preferential use of an upcoming reagent or for calibrating an upcoming reagent, characterized by comprising:
acquiring a suction sequence of a plurality of bottles of reagents input by a user through a human-computer interaction device, and acquiring the placing positions of the plurality of bottles of reagents, wherein the placing positions of the plurality of bottles of reagents are obtained by reading reagent information through an information reading device and according to the reagent information and the setting positions of the information reading device; the multiple bottles of reagents are contained in multiple containers and belong to the same type;
determining the priority sequence of the reagent positions for executing reagent sucking operation according to the placing positions of the plurality of bottles of reagents and the sucking sequence of the plurality of bottles of reagents;
determining the relative displacement of the sucking and injecting mechanism and the reagent bearing mechanism at least according to the priority sequence; wherein the determining of the relative displacement of the pipetting mechanism and the reagent carrying mechanism at least according to the priority order comprises:
determining reagent positions to be subjected to reagent sucking operation according to the priority sequence, and taking the reagents placed on the reagent positions as effective reagents;
planning the action of the reagent bearing mechanism according to the current position coordinate of the reagent position with the priority ranked first and the set position coordinate of the reagent sucking position, so that the effective reagent is transferred to the reagent sucking position;
in the reagent sucking link, the sucking and injecting mechanism and/or the reagent bearing mechanism are driven to move according to the relative displacement of the sucking and injecting mechanism and the reagent bearing mechanism;
controlling the sucking and injecting mechanism to execute reagent sucking operation.
2. The method of claim 1, further comprising, after the reagent pipetting operation: analyzing and managing the surplus of the effective reagent, and determining whether to switch the reagent bottle according to the analysis result;
the step of determining the reagent positions to be subjected to reagent sucking operation according to the priority sequence comprises the following steps:
when the test is started, the first reagent position is used as the reagent position to be subjected to reagent sucking operation according to the priority sequence;
and in the test process, when the reagent bottle needs to be switched, taking the next sequenced reagent position as the reagent position for executing the reagent sucking operation.
3. The method of claim 1, further comprising obtaining user-entered cycle information specifying whether multiple vials of reagent are to be cycled to provide reagent, and thereafter determining the relative displacement of the pipetting mechanism and the reagent carrier based on the prioritization and cycle information.
4. A reagent suction control device for a plurality of bottles of reagents, characterized by comprising:
the information acquisition module is used for acquiring the suction sequence of the multiple bottles of reagents input by a user through human-computer interaction equipment and acquiring the placement positions of the multiple bottles of reagents; the placing positions of the plurality of bottles of reagents are obtained by reading the information of the reagents by the information reading device and according to the information of the reagents and the setting positions of the information reading device, and the plurality of bottles of reagents are reagents which are contained in a plurality of containers and belong to the same type;
the test module is used for determining the priority sequence of reagent positions for executing reagent sucking operation according to the placing positions of the plurality of bottles of reagents and the sucking sequence of the plurality of bottles of reagents, and determining the relative displacement of the sucking and injecting mechanism and the reagent bearing mechanism at least according to the priority sequence; wherein the test module comprises:
the effective reagent determining unit is used for determining reagent positions to be subjected to reagent sucking operation according to priority order and taking the reagents placed on the reagent positions as effective reagents;
the planning unit is used for planning the action of the reagent carrying mechanism according to the current position coordinates of the reagent position with the priority ranked first and the set position coordinates of the reagent sucking position so as to enable the effective reagent to be transferred to the reagent sucking position;
and the sucking and injecting module is used for driving the sucking and injecting mechanism and/or the reagent bearing mechanism to move according to the relative displacement of the sucking and injecting mechanism and the reagent bearing mechanism in a reagent sucking link and controlling the sucking and injecting mechanism to execute reagent sucking operation.
5. The device as claimed in claim 4, further comprising a residual amount management module for analyzing and managing the residual amount of the effective reagent after the reagent sucking operation and determining whether to switch the reagent bottle according to the analysis result; the effective reagent determining unit is used for taking the reagent position which is sequenced at the first as the reagent position for executing reagent sucking operation according to priority sequencing when the test is started, and taking the reagent position which is sequenced at the next as the reagent position for executing reagent sucking operation when the reagent bottle needs to be switched in the test process.
6. The apparatus of claim 5, wherein the remaining amount management module analyzes and manages the remaining amount of the effective reagent by the acquired liquid level detection result and the number of measurements available for each reagent.
7. The apparatus of claim 4, wherein the information obtaining module is further configured to obtain cycling information input by a user, the cycling information specifying whether multiple vials of reagents are to be cycled to provide reagents, and the testing module determines the relative displacement of the pipetting mechanism and the reagent carrier based on the prioritization and the cycling information.
8. A sample analyzer, comprising:
the human-computer interaction equipment is used for providing an input/output interface and an input interface for a user;
the reagent carrying mechanism is used for carrying a reagent and is provided with a plurality of reagent positions for accommodating reagent containers;
the sucking and injecting mechanism is used for sucking the reagent from the reagent disk and injecting the sucked reagent into the reaction cup;
a control system electrically connected with the human-computer interaction device for data interaction with the human-computer interaction device, wherein the control system comprises the reagent sucking control device as claimed in any one of claims 4 to 7.
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CN103675248A (en) * | 2012-09-21 | 2014-03-26 | 深圳迈瑞生物医疗电子股份有限公司 | Biochemical analyzer as well as reagent residue refreshing method and device thereof |
CN104345158A (en) * | 2013-07-30 | 2015-02-11 | 苏州浩欧博生物医药有限公司 | Automatic analysis apparatus and automatic analysis method |
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