CN107281407A - A kind of particle for ease constipation disperse accumulations defaecation of promoting the production of body fluid and preparation method thereof - Google Patents
A kind of particle for ease constipation disperse accumulations defaecation of promoting the production of body fluid and preparation method thereof Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8968—Ophiopogon (Lilyturf)
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Abstract
The invention provides a kind of particle for ease constipation disperse accumulations defaecation of promoting the production of body fluid and preparation method thereof, contain：Angelica extract, dried orange peel extracts, ophiopogon japonicus extract, Gentrin Knotweed P.E, Fructus Monordicae extract, Semen Benincasae extract, Scaphium scaphigerum extract, cassia seed extract, cistanche extracts, Semen Platycladi extract, buckwheat, oatmeal, dextrin, sucrose, distilled water, soluble starch, 75% ethanol.Compared with prior art, ease constipation that what the present invention was provided promote the production of body fluid, the particle of disperse accumulations defaecation use the property of medicine of Chinese medicine gentle, it is safe, enteron aisle moisture can be increased using the active material in natural drug, improve stomach and wriggling digestive function, promote food metabolism and enteron aisle waste discharge, reaching improves effect of constipation.
Description
Technical field
The invention belongs to field of medicaments, and in particular to a kind of particle for ease constipation disperse accumulations defaecation of promoting the production of body fluid and preparation method thereof.
Background technology
Constipation refers to that excrement is detained too long in enteral, and constipated obstructed, defecation cycle stretch-out, or cycle be not long, but excrement matter is dry
Knot, it is difficult to discharge, or excrement matter is not hard, though there is awareness of defecation, just without smooth illness.With people's habits and customs and dietary structure
Change, constipation turns into one of common disease.
What modern medicine thought constipation occurs as multiple factors, is divided into organic, feature and other causes of disease, more due to medicine
The factor such as thing, neuroendocrine disorder or diet, environment, psychology causes.Constipation largely have impact on the life matter of people
Amount, constipation patient expect to have it is a kind of facilitate science to have no side effect safely, and the significant medicine of effect, to help them to break away from constipation
Puzzlement.Motherland's traditional chinese medicine and modern technologies are organically combined to treat constipation, be solve constipation problem direction it
One.
The content of the invention
It is an object of the invention to provide a kind of particle for ease constipation disperse accumulations defaecation of promoting the production of body fluid, containing a variety of high-quality Chinese medicines effectively into
Point, moreover, in the form of granular preparation, absorb it is fast, effective rapidly, conveniently, stably, it is in good taste can it is steady, effectively play medicine
Effect.
Present invention also offers a kind of preparation method of the particle for ease constipation disperse accumulations defaecation of promoting the production of body fluid.
A kind of particle for ease constipation disperse accumulations defaecation of promoting the production of body fluid that the present invention is provided, contains following material and raw material：
Described angelica extract is prepared by the following method：
Weigh Radix Angelicae Sinensis coarse powder appropriate, after immersion, heating and refluxing extraction three times adds 24-28 times and measure water, extracts 0.5- for the first time
2.0h, adds 20-25 times and measures water for the second time, extracts 0.5-1.5h, and third time plus 18-22 times measure water, extraction 0.5-1.5h, each filter
Cross, merging filtrate, be concentrated into viscous pasty state, then be placed on 80-100 DEG C of water-bath and steam to not flow regime, be put in 40-60 DEG C of baking
Dried in case, pulverize and sieve, produce angelica extract, it is standby.
Described dried orange peel extracts are prepared by the following method：
Weigh dried orange peel coarse powder appropriate, after immersion, heating and refluxing extraction three times adds 20-24 times for the first time and measures 60% ethanol, carries
1.0-2.0h is taken, adds 16-20 times to measure 60% ethanol for the second time, 1.0-1.5h is extracted, third time plus 12-16 times measure 60% ethanol,
0.5-1.0h is extracted, every time filtration, merging filtrate is concentrated into viscous pasty state, then be placed on 80-90 DEG C of water-bath and steam to not flowing
State, is put in 50-60 DEG C of baking oven and dries, pulverize and sieve, produce dried orange peel extracts, standby.
Described ophiopogon japonicus extract is prepared by the following method：
Weigh tuber of dwarf lilyturf coarse powder appropriate, after immersion, heating and refluxing extraction three times adds 10-12 times and measure water, extracts 1.0- for the first time
2.0h, adds 8-10 times and measures water for the second time, extracts 1.0-2.0h, and third time plus 8-10 times measure water, extraction 0.5-1.5h, each filter
Cross, merging filtrate, be concentrated into viscous pasty state, then be placed on 90-100 DEG C of water-bath and steam to not flow regime, be put in 45-65 DEG C of baking
Dried in case, pulverize and sieve, produce ophiopogon japonicus extract, it is standby.
Described Gentrin Knotweed P.E is prepared by the following method：
Weigh giant knotweed coarse powder appropriate, after immersion, heating and refluxing extraction three times adds 12-14 times for the first time and measures 70% ethanol, carries
1.5-2.0h is taken, adds 10-12 times to measure 70% ethanol for the second time, 0.5-1.5h is extracted, third time plus 8-10 times are measured 70% ethanol, carried
0.5-1.0h is taken, every time filtration, merging filtrate is concentrated into viscous pasty state, then be placed on 80-95 DEG C of water-bath and steam to not flowing shape
State, is put in 50-65 DEG C of baking oven and dries, pulverize and sieve, produce Gentrin Knotweed P.E, put drier standby.
Described Fructus Monordicae extract is prepared by the following method：
Weigh Momordica grosvenori coarse powder appropriate, after immersion, heating and refluxing extraction three times adds 18-20 times for the first time and measures water, extracts
1.0-2.0h, second plus 14-16 times measure water, extract 1.0-1.5h, third time plus 10-12 times measure water, extract 0.5-1.0h, often
Secondary filtration, merging filtrate is concentrated into viscous pasty state, then is placed on 80-95 DEG C of water-bath and steams to not flow regime, is put in 55-60
Dried in DEG C baking oven, pulverize and sieve, produce Fructus Monordicae extract, it is standby.
Described Semen Benincasae extract is prepared by the following method：
Weigh Semen Benincasae coarse powder appropriate, after immersion, heating and refluxing extraction three times adds 16-18 times for the first time and measures water, extracts
1.0-2.0h, second plus 14-16 times measure water, extract 1.0-2.0h, third time plus 10-14 times measure water, extract 0.5-1.5h, often
Secondary filtration, merging filtrate is concentrated into viscous pasty state, then is placed on 85-90 DEG C of water-bath and steams to not flow regime, is put in 50-70
Dried in DEG C baking oven, pulverize and sieve, produce Semen Benincasae extract, it is standby.
Described Scaphium scaphigerum extract is prepared by the following method：
Weigh sterculia seed coarse powder appropriate, after immersion, heating and refluxing extraction three times adds 24-28 times for the first time and measures water, extracts
1.0-2.5h, second plus 18-22 times measure water, extract 1.0-2.0h, third time plus 16-18 times measure water, extract 0.5-1.5h, often
Secondary filtration, merging filtrate is concentrated into viscous pasty state, then is placed on 80-100 DEG C of water-bath and steams to not flow regime, is put in 55-65
Dried in DEG C baking oven, pulverize and sieve, produce Scaphium scaphigerum extract, it is standby.
Described cassia seed extract is prepared by the following method：
Weigh cassia seed coarse powder appropriate, after immersion, add 10-12 times measures 50% ethanol to heating and refluxing extraction twice, for the first time,
1.0-2.0h is extracted, second plus 8-10 times measure 50% ethanol, extract 1.0-2.0h, every time filtration, merging filtrate is concentrated into viscous
Thick state, then be placed on 80-95 DEG C of water-bath and steam to not flow regime, it is put in 45-60 DEG C of baking oven and dries, pulverizes and sieves, i.e.,
Cassia seed extract is obtained, it is standby.
Described cistanche extracts are prepared by the following method：
Weigh saline cistanche coarse powder appropriate, after immersion, heating and refluxing extraction three times adds 18-25 times for the first time and measures 75% ethanol,
1.5-2.0h is extracted, second plus 12-18 times measure 75% ethanol, extract 1.0-1.5h, third time plus 12-18 times measure 75% second
Alcohol, extracts 1.0-1.5h, every time filtration, merging filtrate is concentrated into viscous pasty state, then is placed on 80-90 DEG C of water-bath and steams to not
Flow regime, is put in 55-65 DEG C of baking oven and dries, pulverize and sieve, produce cistanche extracts, standby.
Described Semen Platycladi extract is prepared by the following method：
Weigh seed of Oriental arborvitae coarse powder appropriate, after immersion, heating and refluxing extraction three times adds 20-22 times for the first time and measures 75% ethanol,
1.0-2.0h is extracted, second plus 18-20 times measure 75% ethanol, extract 1.0-2.0h, third time plus 16-18 times measure 75% second
Alcohol, extracts 0.5-1.5h, every time filtration, merging filtrate is concentrated into viscous pasty state, then is placed on 80-100 DEG C of water-bath and steams to not
Flow regime, is put in 55-60 DEG C of baking oven and dries, pulverize and sieve, produce Semen Platycladi extract, standby.
Described buckwheat is prepared by the following method：
Appropriate buckwheat is taken, crushes, sieves for subsequent use.
Described oatmeal is prepared by the following method：
Appropriate oat is taken, crushes, sieves for subsequent use.
Sieving referred to 80 mesh sieves described in all of above extract and buckwheat, oatmeal preparation process.
A kind of preparation method of the particle for ease constipation disperse accumulations defaecation of promoting the production of body fluid that the present invention is provided, comprises the following steps：
A) angelica extract, dried orange peel extracts, ophiopogon japonicus extract, Gentrin Knotweed P.E, the Momordica grosvenori for weighing formula ratio are extracted
Thing, Semen Benincasae extract, Scaphium scaphigerum extract, cassia seed extract, cistanche extracts, Semen Platycladi extract, buckwheat, swallow
Flour, soluble starch, sucrose, dextrin and distilled water are mixed；
B) it is placed in container, the ethanol of sprayed-out recipe amount 75%, rubs tactile i.e. scattered to holding agglomerating one, use 10-16 mesh sieves, by hand
Extruding sieving granulation, is placed in 40-60 DEG C of baking oven and dries, with 10-30 mesh, 40-80 mesh sieve whole grains, can be by 10-30 mesh sieves, no
It can be the particle of ease constipation, disperse accumulations defaecation of promoting the production of body fluid by the particle of 40-80 mesh sieves.
Various composition in the present invention is as follows：
Gas under Radix Angelicae Sinensis ease constipation, sweet Wen Zhirun leads to internal organs without hindering just, can be obviously improved the deficiency of blood syndrome of blood deficiency and constipation, promotes
Intestines peristalsis, intestines are dry and shit is difficult for improvement, and treatment anti-constipation effect is good.Furthermore effect of its enriching the blood and moisturizing the intestine defaecation makes it be commonly used for blood
Empty dry constipation of intestines.The traditional Chinese medical science thinks essence and blood sharing the same origin, and deficiency of blood person's body fluid is also not enough, the short easy cause constipation of intestinal juice.Radix Angelicae Sinensis, which has, to be mended
The effect of blood promoting blood circulation, so as to relax bowel, reaches the effect for the treatment of blood deficiency and constipation.
Dried orange peel exists《Collected statements on the herbal foundation》In effect be summarized as：" qi-regulating cold dispelling, wide middle row is stagnant, is good for fortune stomach, and smooth profit is dirty
Internal organs ".《Herbal lease making》Described in:" citrus chachiensis hortorum, acrid, bitter, warm.Enter spleen, lung qi and point can dissipate, energy and, energy is dry, can rush down ".The present invention
Play the role of to promote gastric emptying and Intestinal pushing using dried orange peel water extract.Intestines and stomach are had gentle by the volatile oil contained by dried orange peel
Stimulation, can promote the secretion of digestive juice, exclude pneumatosis in intestinal tube, and these functions show gas under its fragrant stomach invigorating and wind dispelling
Effectiveness.
The tuber of dwarf lilyturf is sweet, slight bitter, and cold nature returns stomach, lung channel, contains abundant bioactive ingredients, such as saponins, Gao Yihuang
Ketone and polysaccharide constituents, have functions that Yin nourishing and lung moistening, reinforcing stomach reg fluid, relieving restlessness that clears away heart-fire, clearing heat-fire, stomach strengthening and digestion promoting, for Tianjin
The diseases such as wound is thirsty, Heat Diabetes, dry constipation of intestines.
Giant knotweed can lead to stagnant with pleasant, and qi-regulating treatment for relieving indigestion and constipation helps fortune, and sending down abnormally ascending defaecation improves the conduction of stagnation of liver-QI and stomach-QI influence enteron aisle, had
Relieving constipation by purgation is acted on, for thermojunction stagnation of the circulation of vital energy constipation.
Momordica grosvenori is sweet, sour, cool in nature, has clearing away summerheat, preventing phlegm from forming and stopping coughing, the easypro bone of cool blood, clearing lung-heat ease constipation, laxation toxin expelling and promotes the production of body fluid
The effects such as quenching the thirst, available for treatment constipation, irritated all diseases of quenching one's thirst.Momordica grosvenori is to intestinal tube caused by acetylcholine or barium chloride
Tetanic contraction has antagonism, intestinal tube is relaxed and spasmolysis；Also there is antagonism to intestinal tube relaxation caused by adrenaline,
Intestinal tube is set to recover spontaneous activity.Show that Momordica grosvenori has dual regulation to intestinal tube motion function.
Semen Benincasae is sweet, cool in nature.Returns spleen, small intestinl channel.With clearing lung-heat, resolving sputum, disappear carbuncle, Li Shui function.《Book on Chinese herbal medicine saves normal》：
" natural disposition is put down, and clearing lung-heat is promoted the production of body fluid；Fry warm-natured, ease constipation is with." for lung heat Lung Qi obstraction, hot shifting large intestine, the withered constipation in intestinal dryness Tianjin, this
Invention with waxgourd seed can clearly profit lung heat, relax bowel.In addition, Semen Benincasae oil-containing 14% in wax gourd, can relax bowel.
The sterculia seed is sweet cold in nature, above enters the clear facilitaing lung gas of lung channel, under return large intestine channel gut purge to relax bowel, with controlling constipation with heat retention institute
The top fire-toxicity syndrome of cause.The sterculia seed has the discharge function of mitigation, can control the constipation caused by lung heat intestinal dryness.Its mechanism is the sterculia seed
Increase intestinal contents can produce mechanical irritation after for oral administration, cause reflectivity enterocinesia to increase and cause the generation under rushing down.
Cassia seed bitter, sweet, salty, cold nature, enter liver, kidney, large intestine channel.《Chinese book on Chinese herbal medicine》Load is said：" sharp water defaecation, is cured mainly
Habitual constipation etc.." cassia seed is containing other Multiple components such as Anthraquinones, aphthopyrans ketone, aliphatic acid, with the big constipation of improvement
The effect tie, relaxed bowel.Cassia seed discharge function affirms that mechanism is that, in the case where intestinal bacterium acts on, generation is acted on enteron aisle
Material and play a role.
Saline cistanche enters kidney and large intestine channel, tonifies the kidney and support yang with moistening dryness for relaxing bowels.Saline cistanche water decoction has obvious defecating feces excretion,
Enterocinesia can be improved, suppress the moisture absorption of large intestine, shorten defecation time.The effective substance that saline cistanche relaxes bowel is total oligosaccharides
And galactitol, the problems such as pellet morphology, excrement water content, the propulsion rate and water content of small intestine can be improved.The kind profit of saline cistanche
Intestines lead to internal organs and treated constipation, and available for the treatment all cards of dry constipation of intestines, use is liked by ancient Chinese medicine doctor.In recent years, pharmacological research confirms meat desert
Rong, which has, to improve myenteron motion, improves effect in terms of constipation.
The seed of Oriental arborvitae is sweet, mild-natured；The thoughts of returning home, kidney, large intestine channel.The seed of Oriental arborvitae contains cedar wood alcohol, sitosterol and diterpene constituents, contains again
Fat oil about 14%, and containing a small amount of volatile oil, saponin(e, vitamin etc..Seed of Oriental arborvitae matter moistens greasiness, can relax bowel, for cloudy blood
Deficiency, dysphoria insomnia, dry constipation of intestines etc..
Buckwheat sugariness is cool, there is the wide intestines of appetizing, lower gas disperse accumulations.Buckwheat contains abundant dietary fiber, can improve stomach and
Wriggling digestive function, promotes food metabolism and enteron aisle waste discharge, and reaching improves effect of constipation.Formed sediment in buckwheat containing resistant
Powder.The intake of resistant starch can also increase defecation, to preventing the disease such as constipation from having certain curative effect.
Oat property sweet taste, rich in starch, protein, fat, B family vitamin, niacin, folic acid, pantothenic acid, calcium, iron, meals
The nutritional ingredients such as fiber are eaten, enterogastric peristalsis can be promoted, beneficial to defecation.Dietary fiber in oat can stimulate enteron aisle, shorten big
Just in the residence time of big enteral, improve digestive function, promote human body intestinal canal to wriggle and accelerate swill metabolism, reach ease constipation
Effect of defaecation.
Dextrin is with viscosity is big, thickening property is strong, dissolubility is good, instant capacity is good, carrier-mediated good, the small, moisture absorption that ferments is low, nothing
Peculiar smell, sugariness are low, human body is easy to digest and assimilate, low-heat, low fat the features such as.It is used as excipient, filler, thickener and stably
Agent.
Sucrose is white, odorless, slightly sweetish powder, is extracted from sugar crop beet or sugarcane.Can
With multi-medicament compatibility, diluent, flavouring, excipient etc. are done in solid pharmaceutical preparation.
Soluble starch is white powder, is widely present in the coring and seed of green plants, in potato, corn and beans
Rich content in class plant.Starch property is stable, using safety non-toxic.
In the preparation process of each natural component extract, solvent and extraction conditions are designed according to the active ingredient of raw material,
Ensure extract active constituent content preferably, effect is best.
In what the present invention was provided promote the production of body fluid ease constipation, the particle of disperse accumulations defaecation containing Radix Angelicae Sinensis, dried orange peel, the tuber of dwarf lilyturf, giant knotweed, Momordica grosvenori,
The extract component of the Chinese medicines such as Semen Benincasae, the sterculia seed, cassia seed, saline cistanche, the seed of Oriental arborvitae, can be with qi-regulating cold dispelling, and wide middle row is stagnant, is good for fortune
Stomach, smooth profit internal organs, so as to improve enterocinesia, suppresses the moisture absorption of large intestine, shortens defecation time, reach the mesh that defaecation is healthy and strong
's.This product is safe and convenient to use, gentle comfortable, lasting medicine, work well.
Compared with prior art, the ease constipation of promoting the production of body fluid that provides of the present invention, the particle of disperse accumulations defaecation use the property of medicine of Chinese medicine
Gently, it is safe, enteron aisle moisture can be increased using the active material in natural drug, improve stomach and wriggling digestive function,
Promote food metabolism and enteron aisle waste discharge, reaching improves effect of constipation.
Embodiment
With reference to embodiment, the present invention will be further described.
Embodiment 1
A kind of particle for ease constipation disperse accumulations defaecation of promoting the production of body fluid, contains following material and raw material：
The preparation of 1.1 angelica extracts
Radix Angelicae Sinensis coarse powder 100g is weighed, 0.5h is soaked, heating and refluxing extraction three times adds 24 times of amount water, extracts 1.0h for the first time,
Second plus 20 times of amount water, extract 1.0h, third time plus 18 times of amount water, extract 0.5h, every time filtration, merging filtrate is concentrated into
Viscous pasty state, then be placed on 80 DEG C of water-baths and steam to not flow regime, it is put in 40 DEG C of baking ovens and dries, crushed 80 mesh sieves, i.e.,
Angelica extract is obtained, drier is put standby.
The preparation of 1.2 dried orange peel extracts
Dried orange peel coarse powder 120g is weighed, 0.5h is soaked, heating and refluxing extraction three times adds 20 times of 60% ethanol of amount, carried for the first time
1.0h is taken, second plus 16 times of 60% ethanol of amount extract 1.0h, third time plus 12 times of 60% ethanol of amount, extract 0.5h, every time filter
Cross, merging filtrate, be concentrated into viscous pasty state, then be placed on 80 DEG C of water-baths and steam to not flow regime, be put in 50 DEG C of baking ovens and dry
It is dry, 80 mesh sieves were crushed, dried orange peel extracts are produced, drier are put standby.
The preparation of 1.3 ophiopogon japonicus extracts
Tuber of dwarf lilyturf coarse powder 115g is weighed, 0.5h is soaked, heating and refluxing extraction three times adds 10 times of amount water, extracts 1.0h for the first time,
Second plus 8 times of amount water, extract 1.0h, third time plus 8 times of amount water, extract 0.5h, every time filtration, merging filtrate is concentrated into viscous
Thick state, then be placed on 90 DEG C of water-baths and steam to not flow regime, it is put in 45 DEG C of baking ovens and dries, crushed 80 mesh sieves, and produced
Ophiopogon japonicus extract, puts drier standby.
The preparation of 1.4 Gentrin Knotweed P.Es
Giant knotweed coarse powder 150g is weighed, 0.5h is soaked, heating and refluxing extraction three times adds 12 times of 70% ethanol of amount, carried for the first time
1.5h is taken, second plus 10 times of 70% ethanol of amount extract 1.0h, third time plus 8 times of 70% ethanol of amount, extract 0.5h, every time filter
Cross, merging filtrate, be concentrated into viscous pasty state, then be placed on 80 DEG C of water-baths and steam to not flow regime, be put in 50 DEG C of baking ovens and dry
It is dry, 80 mesh sieves were crushed, Gentrin Knotweed P.E is produced, drier are put standby.
The preparation of 1.5 Fructus Monordicae extracts
Momordica grosvenori coarse powder 100g is weighed, 0.5h is soaked, heating and refluxing extraction three times adds 18 times of amount water, extracted for the first time
1.0h, second plus 14 times of amount water extract 1.0h, third time plus 10 times of amount water, extract 0.5h, every time filtration, merging filtrate is dense
Viscous pasty state is reduced to, then is placed on 80 DEG C of water-baths and steams to not flow regime, is put in 55 DEG C of baking ovens and dries, crushed 80 mesh
Sieve, produces Fructus Monordicae extract, puts drier standby.
The preparation of 1.6 Semen Benincasae extracts
Semen Benincasae coarse powder 100g is weighed, 0.5h is soaked, heating and refluxing extraction three times adds 16 times of amount water, extracted for the first time
1.0h, second plus 14 times of amount water extract 1.0h, third time plus 10 times of amount water, extract 1.0h, every time filtration, merging filtrate is dense
Viscous pasty state is reduced to, then is placed on 85 DEG C of water-baths and steams to not flow regime, is put in 50 DEG C of baking ovens and dries, crushed 80 mesh
Sieve, produces Semen Benincasae extract, puts drier standby.
The preparation of 1.7 Scaphium scaphigerum extracts
Sterculia seed coarse powder 120g is weighed, 0.5h is soaked, heating and refluxing extraction three times adds 24 times of amount water, extracted for the first time
1.0h, second plus 18 times of amount water extract 1.0h, third time plus 16 times of amount water, extract 0.5h, every time filtration, merging filtrate is dense
Viscous pasty state is reduced to, then is placed on 80 DEG C of water-baths and steams to not flow regime, is put in 55 DEG C of baking ovens and dries, crushed 80 mesh
Sieve, produces Scaphium scaphigerum extract, puts drier standby.
The preparation of 1.8 cassia seed extracts
Cassia seed coarse powder 100g is weighed, 0.5h is soaked, heating and refluxing extraction adds 10 times of 50% ethanol of amount twice, for the first time,
1.0h is extracted, second plus 8 times of 50% ethanol of amount extract 1.0h, every time filtration, merging filtrate is concentrated into viscous pasty state, then put
Steamed on 80 DEG C of water-baths to not flow regime, be put in 45 DEG C of baking ovens and dry, crushed 80 mesh sieves, produce cassia seed extraction
Thing, puts drier standby.
The preparation of 1.9 cistanche extracts
Saline cistanche coarse powder 100g is weighed, 0.5h is soaked, heating and refluxing extraction three times adds 18 times of 75% ethanol of amount for the first time,
1.5h is extracted, second plus 12 times of 75% ethanol of amount extract 1.0h, third time plus 12 times of 75% ethanol of amount, extract 1.0h, every time
Filtration, merging filtrate is concentrated into viscous pasty state, then is placed on 90 DEG C of water-baths and steams to not flow regime, is put in 60 DEG C of baking ovens
Drying, crushed 80 mesh sieves, and produced cistanche extracts, and put drier standby.
The preparation of 1.10 Semen Platycladi extracts
Seed of Oriental arborvitae coarse powder 100g is weighed, 0.5h is soaked, heating and refluxing extraction three times adds 20 times of 75% ethanol of amount for the first time,
1.0h is extracted, second plus 18 times of 75% ethanol of amount extract 1.0h, third time plus 16 times of 75% ethanol of amount, extract 0.5h, every time
Filtration, merging filtrate is concentrated into viscous pasty state, then is placed on 80 DEG C of water-baths and steams to not flow regime, is put in 55 DEG C of baking ovens
Drying, crushed 80 mesh sieves, and produced Semen Platycladi extract, and put drier standby.
The preparation of 1.11 buckwheats
400g buckwheats are taken, are crushed with pulverizer, 80 mesh sieves is crossed, is placed in standby in drier.
The preparation of 1.12 oatmeals
400g oats are taken, are crushed with pulverizer, 80 mesh sieves is crossed, is placed in standby in drier.
1.13 promote the production of body fluid ease constipation disperse accumulations defaecation particle preparation method：
A) angelica extract 3g, dried orange peel extracts 2g, ophiopogon japonicus extract 2g, Gentrin Knotweed P.E 1g, Fructus Monordicae extract are taken
1.5g, Semen Benincasae extract 1g, Scaphium scaphigerum extract 2g, cassia seed extract 2g, cistanche extracts 3g, Semen Platycladi extract
1g, buckwheat 10g, oatmeal 12g, soluble starch 25g, sucrose 54g, dextrin 13g and distilled water 8ml are mixed；
B) it is placed in pallet, is rubbed with hand, spray 75% ethanol 1ml, rubs tactile i.e. scattered to holding agglomerating one, use 16 mesh
Sieve, manual expression sieving granulation, is placed in 40 DEG C of baking ovens and dries, with 10 mesh, 80 mesh sieve whole grains, can pass through 10 mesh sieves, it is impossible to be logical
The particle for crossing 80 mesh sieves is promote the production of body fluid ease constipation, the particle of disperse accumulations defaecation.
Embodiment 2
A kind of particle for ease constipation disperse accumulations defaecation of promoting the production of body fluid, includes following raw material：
The preparation of 2.1 angelica extracts
Radix Angelicae Sinensis coarse powder 150g is weighed, 0.5h is soaked, heating and refluxing extraction three times adds 26 times of amount water, extracts 1.5h for the first time,
Second plus 24 times of amount water, extract 1.0h, third time plus 20 times of amount water, extract 1.0h, every time filtration, merging filtrate is concentrated into
Viscous pasty state, then be placed on 80 DEG C of water-baths and steam to not flow regime, it is put in 40 DEG C of baking ovens and dries, crushed 80 mesh sieves, i.e.,
Angelica extract is obtained, drier is put standby.
The preparation of 2.2 dried orange peel extracts
Dried orange peel coarse powder 145g is weighed, 0.5h is soaked, heating and refluxing extraction three times adds 22 times of 60% ethanol of amount, carried for the first time
1.5h is taken, second plus 18 times of 60% ethanol of amount extract 1.0h, third time plus 14 times of 60% ethanol of amount, extract 1.0h, every time filter
Cross, merging filtrate, be concentrated into viscous pasty state, then be placed on 85 DEG C of water-baths and steam to not flow regime, be put in 55 DEG C of baking ovens and dry
It is dry, 80 mesh sieves were crushed, dried orange peel extracts are produced, drier are put standby.
The preparation of 2.3 ophiopogon japonicus extracts
Tuber of dwarf lilyturf coarse powder 180g is weighed, 0.5h is soaked, heating and refluxing extraction three times adds 12 times of amount water, extracts 1.5h for the first time,
Second plus 10 times of amount water, extract 1.5h, third time plus 8 times of amount water, extract 1.0h, every time filtration, merging filtrate is concentrated into viscous
Thick state, then be placed on 95 DEG C of water-baths and steam to not flow regime, it is put in 55 DEG C of baking ovens and dries, crushed 80 mesh sieves, and produced
Ophiopogon japonicus extract, puts drier standby.
The preparation of 2.4 Gentrin Knotweed P.Es
Giant knotweed coarse powder 170g is weighed, 0.5h is soaked, heating and refluxing extraction three times adds 14 times of 70% ethanol of amount, carried for the first time
1.5h is taken, second plus 10 times of 70% ethanol of amount extract 1.0h, third time plus 8 times of 70% ethanol of amount, extract 1.0h, every time filter
Cross, merging filtrate, be concentrated into viscous pasty state, then be placed on 85 DEG C of water-baths and steam to not flow regime, be put in 60 DEG C of baking ovens and dry
It is dry, 80 mesh sieves were crushed, Gentrin Knotweed P.E is produced, drier are put standby.
The preparation of 2.5 Fructus Monordicae extracts
Momordica grosvenori coarse powder 180g is weighed, 0.5h is soaked, heating and refluxing extraction three times adds 20 times of amount water, extracted for the first time
1.5h, second plus 15 times of amount water extract 1.0h, third time plus 10 times of amount water, extract 1.0h, every time filtration, merging filtrate is dense
Viscous pasty state is reduced to, then is placed on 95 DEG C of water-baths and steams to not flow regime, is put in 60 DEG C of baking ovens and dries, crushed 80 mesh
Sieve, produces Fructus Monordicae extract, puts drier standby.
The preparation of 2.6 Semen Benincasae extracts
Semen Benincasae coarse powder 175g is weighed, 0.5h is soaked, heating and refluxing extraction three times adds 16 times of amount water, extracted for the first time
1.5h, second plus 14 times of amount water extract 1.0h, third time plus 12 times of amount water, extract 1.0h, every time filtration, merging filtrate is dense
Viscous pasty state is reduced to, then is placed on 85 DEG C of water-baths and steams to not flow regime, is put in 60 DEG C of baking ovens and dries, crushed 80 mesh
Sieve, produces Semen Benincasae extract, puts drier standby.
The preparation of 2.7 Scaphium scaphigerum extracts
Sterculia seed coarse powder 170g is weighed, 0.5h is soaked, heating and refluxing extraction three times adds 26 times of amount water, extracted for the first time
2.0h, second plus 20 times of amount water extract 1.5h, third time plus 16 times of amount water, extract 1.0h, every time filtration, merging filtrate is dense
Viscous pasty state is reduced to, then is placed on 90 DEG C of water-baths and steams to not flow regime, is put in 60 DEG C of baking ovens and dries, crushed 80 mesh
Sieve, produces Scaphium scaphigerum extract, puts drier standby.
The preparation of 2.8 cassia seed extracts
Cassia seed coarse powder 180g is weighed, 0.5h is soaked, heating and refluxing extraction adds 12 times of 50% ethanol of amount twice, for the first time,
1.5h is extracted, second plus 8 times of 50% ethanol of amount extract 1.0h, every time filtration, merging filtrate is concentrated into viscous pasty state, then put
Steamed on 80 DEG C of water-baths to not flow regime, be put in 55 DEG C of baking ovens and dry, crushed 80 mesh sieves, produce cassia seed extraction
Thing, puts drier standby.
2.9 the preparation of cistanche extracts
Saline cistanche coarse powder 180g is weighed, 0.5h is soaked, heating and refluxing extraction three times adds 19 times of 75% ethanol of amount for the first time,
2.0h is extracted, second plus 15 times of 75% ethanol of amount extract 1.5h, third time plus 15 times of 75% ethanol of amount, extract 1.0h, every time
Filtration, merging filtrate is concentrated into viscous pasty state, then is placed on 90 DEG C of water-baths and steams to not flow regime, is put in 60 DEG C of baking ovens
Drying, crushed 80 mesh sieves, and produced cistanche extracts, and put drier standby.
The preparation of 2.10 Semen Platycladi extracts
Seed of Oriental arborvitae coarse powder 160g is weighed, 0.5h is soaked, heating and refluxing extraction three times adds 20 times of 75% ethanol of amount for the first time,
1.5h is extracted, second plus 18 times of 75% ethanol of amount extract 1.0h, third time plus 16 times of 75% ethanol of amount, extract 1.0h, every time
Filtration, merging filtrate is concentrated into viscous pasty state, then is placed on 90 DEG C of water-baths and steams to not flow regime, is put in 55 DEG C of baking ovens
Drying, crushed 80 mesh sieves, and produced Semen Platycladi extract, and put drier standby.
The preparation of 2.11 buckwheats
450g buckwheats are taken, are crushed with pulverizer, 80 mesh sieves is crossed, is placed in standby in drier.
The preparation of 2.12 oatmeals
300g oats are taken, are crushed with pulverizer, 80 mesh sieves is crossed, is placed in standby in drier.
2.13 promote the production of body fluid ease constipation, the preparation of the particle of disperse accumulations defaecation
A) angelica extract 5g, dried orange peel extracts 4g, ophiopogon japonicus extract 3g, Gentrin Knotweed P.E 2.5g, Momordica grosvenori is taken to extract
Thing 1.5g, Semen Benincasae extract 2g, Scaphium scaphigerum extract 2g, cassia seed extract 5g, cistanche extracts 4g, the seed of Oriental arborvitae are extracted
Thing 2g, buckwheat 18g, oatmeal 11g, soluble starch 22g, sucrose 68g, dextrin 26g and distilled water 10ml are mixed；
B) it is placed in pallet, is rubbed with hand, spray 75% ethanol 1.5ml, rubs tactile i.e. scattered to holding agglomerating one, with 16
Mesh sieve, manual expression sieving granulation, is placed in 45 DEG C of baking ovens and dries, with 10-30 mesh, 40-80 mesh sieve whole grains, can pass through 10 mesh
Sieve, it is impossible to which the particle by 80 mesh sieves is promote the production of body fluid ease constipation, the particle of disperse accumulations defaecation.
Embodiment 3
A kind of particle for ease constipation disperse accumulations defaecation of promoting the production of body fluid, includes following raw material：
The preparation of 3.1 angelica extracts
Radix Angelicae Sinensis coarse powder 200g is weighed, 0.5h is soaked, heating and refluxing extraction three times adds 28 times of amount water, extracts 2.0h for the first time,
Second plus 25 times of amount water, extract 1.5h, third time plus 22 times of amount water, extract 1.5h, every time filtration, merging filtrate is concentrated into
Viscous pasty state, then be placed on 100 DEG C of water-baths and steam to not flow regime, it is put in 60 DEG C of baking ovens and dries, crushed 80 mesh sieves, i.e.,
Angelica extract is obtained, drier is put standby.
The preparation of 3.2 dried orange peel extracts
Dried orange peel coarse powder 200g is weighed, 0.5h is soaked, heating and refluxing extraction three times adds 24 times of 60% ethanol of amount, carried for the first time
2.0h is taken, second plus 20 times of 60% ethanol of amount extract 1.5h, third time plus 16 times of 60% ethanol of amount, extract 1.0h, every time filter
Cross, merging filtrate, be concentrated into viscous pasty state, then be placed on 90 DEG C of water-baths and steam to not flow regime, be put in 60 DEG C of baking ovens and dry
It is dry, 80 mesh sieves were crushed, dried orange peel extracts are produced, drier are put standby.
The preparation of 3.3 ophiopogon japonicus extracts
Tuber of dwarf lilyturf coarse powder 190g is weighed, 0.5h is soaked, heating and refluxing extraction three times adds 12 times of amount water, extracts 2.0h for the first time,
Second plus 10 times of amount water, extract 1.5h, third time plus 8 times of amount water, extract 1.0h, every time filtration, merging filtrate is concentrated into viscous
Thick state, then be placed on 100 DEG C of water-baths and steam to not flow regime, it is put in 65 DEG C of baking ovens and dries, crushed 80 mesh sieves, and produced
Ophiopogon japonicus extract, puts drier standby.
The preparation of 3.4 Gentrin Knotweed P.Es
Giant knotweed coarse powder 200g is weighed, 0.5h is soaked, heating and refluxing extraction three times adds 14 times of 70% ethanol of amount, carried for the first time
2.0h is taken, second plus 12 times of 70% ethanol of amount extract 1.5h, third time plus 10 times of 70% ethanol of amount, extract 1.0h, every time filter
Cross, merging filtrate, be concentrated into viscous pasty state, then be placed on 95 DEG C of water-baths and steam to not flow regime, be put in 65 DEG C of baking ovens and dry
It is dry, 80 mesh sieves were crushed, Gentrin Knotweed P.E is produced, drier are put standby.
The preparation of 3.5 Fructus Monordicae extracts
Momordica grosvenori coarse powder 200g is weighed, 0.5h is soaked, heating and refluxing extraction three times adds 20 times of amount water, extracted for the first time
2.0h, second plus 16 times of amount water extract 1.5h, third time plus 12 times of amount water, extract 1.0h, every time filtration, merging filtrate is dense
Viscous pasty state is reduced to, then is placed on 95 DEG C of water-baths and steams to not flow regime, is put in 60 DEG C of baking ovens and dries, crushed 80 mesh
Sieve, produces Fructus Monordicae extract, puts drier standby.
The preparation of 3.6 Semen Benincasae extracts
Semen Benincasae coarse powder 185g is weighed, 0.5h is soaked, heating and refluxing extraction three times adds 18 times of amount water, extracted for the first time
2.0h, second plus 16 times of amount water extract 1.0h, third time plus 10 times of amount water, extract 1.0h, every time filtration, merging filtrate is dense
Viscous pasty state is reduced to, then is placed on 90 DEG C of water-baths and steams to not flow regime, is put in 70 DEG C of baking ovens and dries, crushed 80 mesh
Sieve, produces Semen Benincasae extract, puts drier standby.
The preparation of 3.7 Scaphium scaphigerum extracts
Sterculia seed coarse powder 200g is weighed, 0.5h is soaked, heating and refluxing extraction three times adds 28 times of amount water, extracted for the first time
2.5h, second plus 22 times of amount water extract 2.0h, third time plus 18 times of amount water, extract 1.5h, every time filtration, merging filtrate is dense
Viscous pasty state is reduced to, then is placed on 100 DEG C of water-baths and steams to not flow regime, is put in 65 DEG C of baking ovens and dries, crushed 80 mesh
Sieve, produces Scaphium scaphigerum extract, puts drier standby.
The preparation of 3.8 cassia seed extracts
Cassia seed coarse powder 180g is weighed, 0.5h is soaked, heating and refluxing extraction adds 12 times of 50% ethanol of amount twice, for the first time,
2.0h is extracted, second plus 8 times of 50% ethanol of amount extract 1.0h, every time filtration, merging filtrate is concentrated into viscous pasty state, then put
Steamed on 95 DEG C of water-baths to not flow regime, be put in 60 DEG C of baking ovens and dry, crushed 80 mesh sieves, produce cassia seed extraction
Thing, puts drier standby.
The preparation of 3.9 cistanche extracts
Saline cistanche coarse powder 200g is weighed, 0.5h is soaked, heating and refluxing extraction three times adds 25 times of 75% ethanol of amount for the first time,
2.0h is extracted, second plus 18 times of 75% ethanol of amount extract 1.5h, third time plus 18 times of 75% ethanol of amount, extract 1.5h, every time
Filtration, merging filtrate is concentrated into viscous pasty state, then is placed on 90 DEG C of water-baths and steams to not flow regime, is put in 60 DEG C of baking ovens
Drying, crushed 80 mesh sieves, and produced cistanche extracts, and put drier standby.
The preparation of 3.10 Semen Platycladi extracts
Seed of Oriental arborvitae coarse powder 200g is weighed, 0.5h is soaked, heating and refluxing extraction three times adds 22 times of 75% ethanol of amount for the first time,
2.0h is extracted, second plus 20 times of 75% ethanol of amount extract 2.0h, third time plus 18 times of 75% ethanol of amount, extract 1.5h, every time
Filtration, merging filtrate is concentrated into viscous pasty state, then is placed on 100 DEG C of water-baths and steams to not flow regime, is put in 60 DEG C of baking ovens
Drying, crushed 80 mesh sieves, and produced Semen Platycladi extract, and put drier standby.
The preparation of 3.11 buckwheats
400g buckwheats are taken, are crushed with pulverizer, 80 mesh sieves is crossed, is placed in standby in drier.
The preparation of 3.12 oatmeals
300g oats are taken, are crushed with pulverizer, 80 mesh sieves is crossed, is placed in standby in drier.
3.13 promote the production of body fluid ease constipation, the preparation of the particle of disperse accumulations defaecation
A) angelica extract 8g, dried orange peel extracts 6g, ophiopogon japonicus extract 5.5g, Gentrin Knotweed P.E 3.5g, Momordica grosvenori is taken to carry
Thing 3g, Semen Benincasae extract 3g, Scaphium scaphigerum extract 4g, cassia seed extract 8g, cistanche extracts 5g, the seed of Oriental arborvitae is taken to extract
Thing 5g, buckwheat 20g, oatmeal 14g, soluble starch 28g, sucrose 76g, dextrin 36g and distilled water 13ml are mixed；
B) it is placed in pallet, is rubbed with hand, spray 75% ethanol 2ml, rubs tactile i.e. scattered to holding agglomerating one, use 16 mesh
Sieve, manual expression sieving granulation, is placed in 45 DEG C of baking ovens and dries, with 10 mesh, 80 mesh sieve whole grains, can pass through 10 mesh sieves, it is impossible to be logical
The particle for crossing 80 mesh sieves is promote the production of body fluid ease constipation, the particle of disperse accumulations defaecation.
Embodiment 4
The physical and chemical index of embodiment 1,2,3 is as follows：
4.1 character
The brown yellow granule that this product is suitable size, homogeneous, appearance is complete, smell delicate fragrance, taste is sour-sweet.
The inspection of 4.2 size distributions
The different medicine sieve of screen size is stacked up from high to low by the order of mesh number from small to large, by ready-made content
Particle is poured into uppermost sieve, is slowly shaken the medicine sieve stacked up, particle of different sizes is separated, gained is respectively sieved
Percentage such as table 1 in number.
Percentage shared by particle in each screen size of table 1
| Screen size | Percentage (%) |
| 10 mesh | 0 |
| 20 mesh | 74.4 |
| 40 mesh | 23.6 |
| 60 mesh | 2 |
| 80 mesh | 0 |
4.3 content mobility are checked
Using fixed conical bottom method, chassis is a culture dish, will be overlapping above and below two glass funnels, is fixed on brandreth
On platform, lower hopper outlet and chassis distance are 1cm, take sample to be slowly added into from upper funnel, make sample by two funnels
Buffering is gradually deposited on chassis, cone is formed, untill obtaining highest cone.Cone height h is determined, every kind of sample is respectively surveyed
Three times, average, angle of repose a is measured by a=arctg (h/r).Income value is 0.38, arctg=21 °<30 °, mobility compared with
It is good.
4.4 treatment anti-constipation effect inspections
Volunteer's (18-65 Sui, 120 people) is chosen, bath oral granule is after seven days, and patient's enterogastric peristalsis is unobstructed, during defecation
Between shorten, constipation situation improved, and the effect with preferably treatment constipation is used for a long time.
The 4.5 particle synthesis effect expeditions
Feel to evaluate the ease constipation of promoting the production of body fluid that embodiment 1,2,3 is made, effect of the particle of disperse accumulations defaecation following with probation.
Using opinion poll point system, man, women (men and women half and half) conduct for having constipation situation of 120 18-65 Sui age brackets are chosen
Object on probation, is arbitrarily divided into three groups, and the particle of the treatment constipation of the preparation of embodiment 1,2,3 is taken respectively.Take twice within one day,
Use time is one week.Every using effect total score is 5 points：5 points are best result, represent fine, very satisfied；4 points are preferable；
3 points are to receive；Less than 3 points are bad, it is impossible to received.It is below every average.It the results are shown in Table 2：
The resultant effect of table 2 is investigated
The ease constipation of promoting the production of body fluid of the invention provided, the particle of disperse accumulations defaecation can lead to internal organs without hindering just with gas under ease constipation in summary,
Pleasant logical stagnant, qi-regulating treatment for relieving indigestion and constipation helps fortune, and sending down abnormally ascending defaecation improves the conduction of stagnation of liver-QI and stomach-QI influence enteron aisle；Constipation can be obviously improved simultaneously
Deficiency of blood syndrome, promote intestines peristalsis, improve intestines are dry and shit is difficult, there is relieving constipation by purgation to be used, treatment anti-constipation effect it is good.
Claims (10)
1. a kind of particle for ease constipation disperse accumulations defaecation of promoting the production of body fluid, it is characterised in that described to contain following material and raw material：
2. the particle of ease constipation disperse accumulations defaecation according to claim 1 of promoting the production of body fluid, it is characterised in that described angelica extract leads to
Cross following methods preparation：
Weigh Radix Angelicae Sinensis coarse powder appropriate, after immersion, heating and refluxing extraction three times adds 24-28 times and measure water, extracts 0.5- for the first time
2.0h, adds 20-25 times and measures water for the second time, extracts 0.5-1.5h, and third time plus 18-22 times measure water, extraction 0.5-1.5h, each filter
Cross, merging filtrate, be concentrated into viscous pasty state, then be placed on 80-100 DEG C of water-bath and steam to not flow regime, be put in 40-60 DEG C of baking
Dried in case, pulverize and sieve, produce angelica extract, it is standby.
3. the particle of ease constipation disperse accumulations defaecation according to claim 1 or 2 of promoting the production of body fluid, it is characterised in that described dried orange peel is extracted
Thing is prepared by the following method：
Weigh dried orange peel coarse powder appropriate, after immersion, heating and refluxing extraction three times adds 20-24 times for the first time and measures 60% ethanol, extracts
1.0-2.0h, adds 16-20 times and measures 60% ethanol for the second time, extracts 1.0-1.5h, and third time plus 12-16 times are measured 60% ethanol, carried
0.5-1.0h is taken, every time filtration, merging filtrate is concentrated into viscous pasty state, then be placed on 80-90 DEG C of water-bath and steam to not flowing shape
State, is put in 50-60 DEG C of baking oven and dries, pulverize and sieve, produce dried orange peel extracts, standby.
4. the particle of the ease constipation disperse accumulations defaecation of promoting the production of body fluid according to claim any one of 1-3, it is characterised in that the described tuber of dwarf lilyturf
Extract is prepared by the following method：
Weigh tuber of dwarf lilyturf coarse powder appropriate, after immersion, heating and refluxing extraction three times adds 10-12 times and measure water, extracts 1.0- for the first time
2.0h, adds 8-10 times and measures water for the second time, extracts 1.0-2.0h, and third time plus 8-10 times measure water, extraction 0.5-1.5h, each filter
Cross, merging filtrate, be concentrated into viscous pasty state, then be placed on 90-100 DEG C of water-bath and steam to not flow regime, be put in 45-65 DEG C of baking
Dried in case, pulverize and sieve, produce ophiopogon japonicus extract, it is standby.
5. the particle of the ease constipation disperse accumulations defaecation of promoting the production of body fluid according to claim any one of 1-4, it is characterised in that described giant knotweed
Extract is prepared by the following method：
Weigh giant knotweed coarse powder appropriate, after immersion, heating and refluxing extraction three times adds 12-14 times for the first time and measures 70% ethanol, extracts
1.5-2.0h, adds 10-12 times and measures 70% ethanol for the second time, extracts 0.5-1.5h, and third time plus 8-10 times measure 70% ethanol, extraction
0.5-1.0h, filtration every time, merging filtrate is concentrated into viscous pasty state, then is placed on 80-95 DEG C of water-bath and steams to not flowing shape
State, is put in 50-65 DEG C of baking oven and dries, pulverize and sieve, produce Gentrin Knotweed P.E, put drier standby.
6. the particle of the ease constipation disperse accumulations defaecation of promoting the production of body fluid according to claim any one of 1-5, it is characterised in that described arhat
Berry extract is prepared by the following method：
Weigh Momordica grosvenori coarse powder appropriate, after immersion, heating and refluxing extraction three times adds 18-20 times and measure water, extracts 1.0- for the first time
2.0h, adds 14-16 times and measures water for the second time, extracts 1.0-1.5h, and third time plus 10-12 times measure water, extraction 0.5-1.0h, each filter
Cross, merging filtrate, be concentrated into viscous pasty state, then be placed on 80-95 DEG C of water-bath and steam to not flow regime, be put in 55-60 DEG C of baking
Dried in case, pulverize and sieve, produce Fructus Monordicae extract, it is standby.
7. the particle of the ease constipation disperse accumulations defaecation of promoting the production of body fluid according to claim any one of 1-6, it is characterised in that described wax gourd
Benevolence extract is prepared by the following method：
Weigh Semen Benincasae coarse powder appropriate, after immersion, heating and refluxing extraction three times adds 16-18 times and measure water, extracts 1.0- for the first time
2.0h, adds 14-16 times and measures water for the second time, extracts 1.0-2.0h, and third time plus 10-14 times measure water, extraction 0.5-1.5h, each filter
Cross, merging filtrate, be concentrated into viscous pasty state, then be placed on 85-90 DEG C of water-bath and steam to not flow regime, be put in 50-70 DEG C of baking
Dried in case, pulverize and sieve, produce Semen Benincasae extract, it is standby.
8. the particle of the ease constipation disperse accumulations defaecation of promoting the production of body fluid according to claim any one of 1-7, it is characterised in that described is fat big
Extra large extract is prepared by the following method：
Weigh sterculia seed coarse powder appropriate, after immersion, heating and refluxing extraction three times adds 24-28 times and measure water, extracts 1.0- for the first time
2.5h, adds 18-22 times and measures water for the second time, extracts 1.0-2.0h, and third time plus 16-18 times measure water, extraction 0.5-1.5h, each filter
Cross, merging filtrate, be concentrated into viscous pasty state, then be placed on 80-100 DEG C of water-bath and steam to not flow regime, be put in 55-65 DEG C of baking
Dried in case, pulverize and sieve, produce Scaphium scaphigerum extract, it is standby；
Described cassia seed extract is prepared by the following method：
Weigh cassia seed coarse powder appropriate, after immersion, add 10-12 times measures 50% ethanol to heating and refluxing extraction twice, for the first time, extracts
1.0-2.0h, adds 8-10 times and measures 50% ethanol for the second time, extracts 1.0-2.0h, every time filtration, and merging filtrate is concentrated into thick
State, then be placed on 80-95 DEG C of water-bath and steam to not flow regime, it is put in 45-60 DEG C of baking oven and dries, pulverizes and sieves, produce certainly
Pine torch extract, it is standby.
9. the particle of the ease constipation disperse accumulations defaecation of promoting the production of body fluid according to claim any one of 1-8, it is characterised in that described meat desert
Rong's extract is prepared by the following method：
Weigh saline cistanche coarse powder appropriate, after immersion, heating and refluxing extraction three times adds 18-25 times for the first time and measures 75% ethanol, extracts
1.5-2.0h, adds 12-18 times and measures 75% ethanol for the second time, extracts 1.0-1.5h, and third time plus 12-18 times are measured 75% ethanol, carried
1.0-1.5h is taken, every time filtration, merging filtrate is concentrated into viscous pasty state, then be placed on 80-90 DEG C of water-bath and steam to not flowing shape
State, is put in 55-65 DEG C of baking oven and dries, pulverize and sieve, produce cistanche extracts, standby；
Described Semen Platycladi extract is prepared by the following method：
Weigh seed of Oriental arborvitae coarse powder appropriate, after immersion, heating and refluxing extraction three times adds 20-22 times for the first time and measures 75% ethanol, extracts
1.0-2.0h, adds 18-20 times and measures 75% ethanol for the second time, extracts 1.0-2.0h, and third time plus 16-18 times are measured 75% ethanol, carried
0.5-1.5h is taken, every time filtration, merging filtrate is concentrated into viscous pasty state, then be placed on 80-100 DEG C of water-bath and steam to not flowing
State, is put in 55-60 DEG C of baking oven and dries, pulverize and sieve, produce Semen Platycladi extract, standby.
10. a kind of preparation method of the particle of the ease constipation disperse accumulations defaecation of promoting the production of body fluid described in any one of claim 1-9, its feature exists
In the preparation method comprises the following steps：
A) angelica extract of formula ratio, dried orange peel extracts, ophiopogon japonicus extract, Gentrin Knotweed P.E, Fructus Monordicae extract, winter are weighed
Edible kernel of melon seeds extract, Scaphium scaphigerum extract, cassia seed extract, cistanche extracts, Semen Platycladi extract, buckwheat, oatmeal,
Soluble starch, sucrose, dextrin and distilled water are mixed；
B) it is placed in container, the ethanol of sprayed-out recipe amount 75%, rubs tactile i.e. scattered to holding agglomerating one, use 10-16 mesh sieves, manual expression
Sieving granulation, is placed in 40-60 DEG C of baking oven and dries, with 10-30 mesh, 40-80 mesh sieve whole grains, can pass through 10-30 mesh sieves, it is impossible to logical
The particle for crossing 40-80 mesh sieves is promote the production of body fluid ease constipation, the particle of disperse accumulations defaecation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710624967.0A CN107281407A (en) | 2017-07-27 | 2017-07-27 | A kind of particle for ease constipation disperse accumulations defaecation of promoting the production of body fluid and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710624967.0A CN107281407A (en) | 2017-07-27 | 2017-07-27 | A kind of particle for ease constipation disperse accumulations defaecation of promoting the production of body fluid and preparation method thereof |
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| CN107281407A true CN107281407A (en) | 2017-10-24 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201710624967.0A Pending CN107281407A (en) | 2017-07-27 | 2017-07-27 | A kind of particle for ease constipation disperse accumulations defaecation of promoting the production of body fluid and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110463799A (en) * | 2018-05-10 | 2019-11-19 | 岳怀芬 | A kind of wild plant composition of protect liver constipation-relieving tea |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1348699A (en) * | 2001-10-17 | 2002-05-15 | 颜自红 | Sugar-free eight-treasure health tea |
| CN104958646A (en) * | 2015-07-28 | 2015-10-07 | 青岛蓝盛洋医药生物科技有限责任公司 | Chinese medicinal preparation for relaxing bowels and preparation method thereof |
-
2017
- 2017-07-27 CN CN201710624967.0A patent/CN107281407A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1348699A (en) * | 2001-10-17 | 2002-05-15 | 颜自红 | Sugar-free eight-treasure health tea |
| CN104958646A (en) * | 2015-07-28 | 2015-10-07 | 青岛蓝盛洋医药生物科技有限责任公司 | Chinese medicinal preparation for relaxing bowels and preparation method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110463799A (en) * | 2018-05-10 | 2019-11-19 | 岳怀芬 | A kind of wild plant composition of protect liver constipation-relieving tea |
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Application publication date: 20171024 |
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