CN107281308A - A kind of heart and gallbladder deficiency of vital energy that improves causes health products of insomnia and preparation method thereof - Google Patents

A kind of heart and gallbladder deficiency of vital energy that improves causes health products of insomnia and preparation method thereof Download PDF

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Publication number
CN107281308A
CN107281308A CN201710486293.2A CN201710486293A CN107281308A CN 107281308 A CN107281308 A CN 107281308A CN 201710486293 A CN201710486293 A CN 201710486293A CN 107281308 A CN107281308 A CN 107281308A
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parts
heart
insomnia
vital energy
health products
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赵树卫
张博
冯金磊
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Tianjin Golden Hall Biological Technology Co Ltd
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Tianjin Golden Hall Biological Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/02Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/68Plantaginaceae (Plantain Family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/79Schisandraceae (Schisandra family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
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  • Engineering & Computer Science (AREA)
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  • Medicines Containing Plant Substances (AREA)

Abstract

A kind of heart and gallbladder deficiency of vital energy that improves causes health products of insomnia and preparation method thereof, is made up of the raw material of following proportion by weight:10 20 parts of spina date seed, 5 20 parts of keel, 5 20 parts of plantain seed, 2 10 parts of Poria cocos, 2 10 parts of the fruit of Chinese magnoliavine, 2 10 parts of ginseng, 15 parts of radix glycyrrhizae, 8 12 parts of maltodextrin.The present invention is a kind of health food for having and improving the heart and gallbladder deficiency of vital energy, is worth using Chinese medicine, reduces the insomnia incidence of disease of people, improve palpitation with fear it is not peaceful, timid it is kind probably, night sleep dreaminess, shortness of breath uncomfortable in chest the problems such as, can long-term taking have no toxic side effect;The preparation method of the insurance product, can ensure that this method make containing improve the heart and gallbladder deficiency of vital energy cause insomnia health products during it is easy to operate, it is easy to control, be easy to promote, it is easy to accomplish standardization, standardization, factorial praluction, it is ensured that the stability of product.

Description

A kind of heart and gallbladder deficiency of vital energy that improves causes health products of insomnia and preparation method thereof
Technical field
The invention belongs to health products processing technique field, and in particular to a kind of improvement heart and gallbladder deficiency of vital energy causes the health products of insomnia And manufacture craft.
Background technology
With the fast development of economic society, the continuous quickening of rhythm of life, because the heart and gallbladder deficiency of vital energy causes the incidence of disease of having a sleepless night Constantly rise.Insomnia mostly occurs among people from workplace, is all often that operating pressure is too big, and psychology puts upon the full stretch what is caused.It is popular Disease learns investigation display, and the insomnia incidence of disease is 33% in the U.S., is 4%-22% in Europe, 10%-20% is also up in China.It is this Phrenoblabia will have a strong impact on the normal life of white collar in workplace, its very important presence.For how to improve insomnia Situation, except psychological regulation, using some there is the food of sleeping effect to be also good method.
That circulates on the market at present has the health care for improving sleep function through what State Food and Drug Administration ratified Food is not a lot, and insomnia has become a kind of social problem, and almost everyone ats fault the experience of dormancy, or The influence for having received sleep insufficiency and having brought, it is very big with the health food demand market potential for improving sleep function, criticize The need for the accurate health food with improvement sleep function far can not meet market, with the health food for improving sleep Market development space is huge.
The content of the invention
The technical problems to be solved by the invention are to improve the heart and gallbladder deficiency of vital energy there is provided one kind in view of the shortcomings of the prior art, can The improvement heart and gallbladder deficiency of vital energy that long-term taking has no toxic side effect causes health products of insomnia and preparation method thereof.
The technical problems to be solved by the invention are realized by following technical scheme.One kind improves the heart and gallbladder deficiency of vital energy Cause the health products of insomnia, be characterized in, be made up of the raw material of following proportion by weight:10-20 parts of spina date seed, keel 5-20 Part, 5-20 parts of plantain seed, 2-10 parts of Poria cocos, 2-10 parts of the fruit of Chinese magnoliavine, 2-10 parts of ginseng, 1-5 parts of radix glycyrrhizae, 8-12 parts of maltodextrin; Its preparation method is:(1)Extract:Take the spina date seed of above-mentioned raw materials quality proportioning, keel, plantain seed, Poria cocos, the fruit of Chinese magnoliavine, ginseng, Radix glycyrrhizae, plus distilled water refluxing extraction, Extracting temperature are 90-100 DEG C, and the water of 500-540g weight is added for the first time, extract 1.5- After 2.5 hours, the water of second of addition 410-440g weight is extracted 0.5-1.5 hours;(2)Filtering merges extract solution, in 60- Density is concentrated under reduced pressure under conditions of 80 DEG C for 1.05-1.25g/ml, the maltodextrin for stating raw material mass mixture ratio is added, continues to subtract Pressure is concentrated to dryness, and is taken out, is ground into fine powder with pulverizer;(3)Load capsule by every 0.2-0.6g, you can be made.
It is preferred that, it is made up of the raw material of following proportion by weight:10 parts of spina date seed, 5 parts of keel, 5 parts of plantain seed, Poria cocos 2 Part, 2 parts of the fruit of Chinese magnoliavine, 2 parts of ginseng, 1 part of radix glycyrrhizae, 8 parts of maltodextrin.
It is preferred that, it is made up of the raw material of following proportion by weight:20 parts of spina date seed, 20 parts of keel, 20 parts of plantain seed, Poria cocos 10 parts, 10 parts of the fruit of Chinese magnoliavine, 10 parts of ginseng, 5 parts of radix glycyrrhizae, 12 parts of maltodextrin.
It is preferred that, it is made up of the raw material of following proportion by weight:15 parts of spina date seed, 10 parts of keel, 10 parts of plantain seed, Poria cocos 5 parts, 5 parts of the fruit of Chinese magnoliavine, 5 parts of ginseng, 2 parts of radix glycyrrhizae, 10 parts of maltodextrin.
It is preferred that, the step(1)Middle Extracting temperature is 95 DEG C, and the water of 520g weight is added for the first time, is extracted 2 hours, The water of second of addition 416g weight, is extracted 1 hour.
It is preferred that, the step(2)It is 1.15 that density is concentrated under reduced pressure under conditions of 70 DEG C.
It is preferred that, the step(3)In every 0.4g load capsule.
Use scope and method:Formula be applied to palpitation with fear caused by the heart and gallbladder deficiency of vital energy it is not peaceful, timid it is kind probably, night sleeps dreaminess, chest Sulks are short, tongue nature is light, thin white, the thin string of arteries and veins of tongue is powerless.Half an hour takes after meal, 2-4, daily 2-3 times, is within one month a treatment Journey, can long-term taking have no toxic side effect.
Compared with prior art, the present invention is a kind of health food for having and improving the heart and gallbladder deficiency of vital energy, is worth using Chinese medicine, Reduce the insomnia incidence of disease of people, improve palpitation with fear it is not peaceful, timid it is kind probably, night sleep dreaminess, shortness of breath uncomfortable in chest the problems such as, can be long-term Take and have no toxic side effect;The preparation method of the insurance product, can ensure that this method causes insomnia in making containing the heart and gallbladder deficiency of vital energy is improved Health products during it is easy to operate, it is easy to control, be easy to promote, it is easy to accomplish standardization, standardization, factorial praluction, protect Demonstrate,prove the stability of product.
Embodiment
To make the purpose, technical scheme and advantage of the embodiment of the present invention clearer, below in the embodiment of the present invention Technical scheme is clearly and completely described, it is clear that described embodiment is only a part of embodiment of the invention, without It is whole embodiments.
Based on the embodiment in the present invention, those of ordinary skill in the art are obtained under the premise of creative work is not made The every other embodiment obtained, belongs to the scope of protection of the invention.
A kind of embodiment 1, heart and gallbladder deficiency of vital energy that improves causes the health products of insomnia, is made up of the raw material of following proportion by weight: 10-20 parts of spina date seed, 5-20 parts of keel, 5-20 parts of plantain seed, 2-10 parts of Poria cocos, 2-10 parts of the fruit of Chinese magnoliavine, 2-10 parts of ginseng, radix glycyrrhizae 1-5 parts, 8-12 parts of maltodextrin;Its preparation method is:(1)Extract:Take the spina date seed, keel, car of above-mentioned raw materials quality proportioning Preceding son, Poria cocos, the fruit of Chinese magnoliavine, ginseng, radix glycyrrhizae, plus distilled water refluxing extraction, Extracting temperature are 90-100 DEG C, for the first time addition 500- The water of 540g weight, after extracting 1.5-2.5 hours, the water of second of addition 410-440g weight is extracted 0.5-1.5 hours;(2) Filtering merges extract solution, and density is concentrated under reduced pressure under conditions of 60-80 DEG C for 1.05-1.25g/ml, adds and states material quality The maltodextrin of proportioning, continues to be concentrated under reduced pressure into drying, takes out, is ground into fine powder with pulverizer;(3)Filled by every 0.2-0.6g Enter capsule, you can be made.Spina date seed also known as jujube kernel, mountain jujube benevolence, wild jujube, time of the year when autumn changes into winter harvesting ripening fruits, remove pulp and Nucleocapsid, collects seed, dries.Its property is sweet, acid, puts down.Enter liver, courage, the heart channel of Hang-Shaoyin.Major function:Tonifying liver, calming heart, arrest sweating promotes the production of body fluid.Acid Jujube kernel is calming the nerves, there is its original opinion in insomnia field, and evident in efficacy, by doctor patient's laudatory title " sleeping fruit in east ".Traditional Chinese medical science allusion quotation Nationality《Sheng Nong's herbal classic》In it is on the books very early, wild jujube can " five viscera settling, macrobiosis of making light of one's life by commiting suicide ".So, it must not look down upon this Wild fruit, it has very big medical value, can play a part of nourishing the liver, calming heart, calm the nerves, arrest sweating.It is medically commonly used to control Treat neurasthenia, vexed insomnia, dreaminess, night sweat, easily frightened etc. disease.Meanwhile, certain strengthening by means of tonics effect can be reached again.Common Chinese medicine " calming soporific ball ", is made up using spina date seed of main component.The bright wild jujube of modern study table benevolence has significant calmness Syngignoscism, there is obvious inhibitory action to animal spontaneous activity or passive activity, and spina date seed water decoction is gavaged or abdominal cavity note Penetrate, no matter daytime or night, normal condition or caffeine excitatory state also show as tranquilizing soporific effect.
Embodiment 2, the improvement heart and gallbladder deficiency of vital energy according to embodiment 1 causes in the health products of insomnia, by following mass parts The raw material composition of proportioning:10 parts of spina date seed, 5 parts of keel, 5 parts of plantain seed, 2 parts of Poria cocos, 2 parts of the fruit of Chinese magnoliavine, 2 parts of ginseng, radix glycyrrhizae 1 Part, 8 parts of maltodextrin.
Embodiment 3, the improvement heart and gallbladder deficiency of vital energy according to embodiment 1 or 2 causes in the health products of insomnia, by following quality The raw material composition of part proportioning:20 parts of spina date seed, 20 parts of keel, 20 parts of plantain seed, 10 parts of Poria cocos, 10 parts of the fruit of Chinese magnoliavine, 10 parts of ginseng, 5 parts of radix glycyrrhizae, 12 parts of maltodextrin.
Embodiment 4, the improvement heart and gallbladder deficiency of vital energy according to embodiment 1 or 2 or 3 causes in the health products of insomnia, by following The raw material composition of proportion by weight:15 parts of spina date seed, 10 parts of keel, 10 parts of plantain seed, 5 parts of Poria cocos, 5 parts of the fruit of Chinese magnoliavine, ginseng 5 Part, 2 parts of radix glycyrrhizae, 10 parts of maltodextrin.
Embodiment 5, the improvement heart and gallbladder deficiency of vital energy according to embodiment any one of 1-4 causes in the health products of insomnia, described Step(1)Middle Extracting temperature is 95 DEG C, and the water of 520g weight is added for the first time, is extracted 2 hours, and 416g weight is added for the second time Water, is extracted 1 hour.
Embodiment 6, the improvement heart and gallbladder deficiency of vital energy according to embodiment any one of 1-5 causes in the health products of insomnia, described Step(2)It is 1.15 that density is concentrated under reduced pressure under conditions of 70 DEG C.
Embodiment 7, the improvement heart and gallbladder deficiency of vital energy according to embodiment any one of 1-6 causes in the health products of insomnia, described Step(3)In every 0.4g load capsule.
Health products having a sleepless night and preparation method thereof are caused to carry out a kind of heart and gallbladder deficiency of vital energy that improves provided by the present invention above It is discussed in detail, specific case used herein is set forth to the principle and embodiment of the present invention, above example Explanation be only intended to help to understand the method and its core concept of the present invention;Simultaneously for those of ordinary skill in the art, According to the thought of the present invention, it will change in specific embodiments and applications, in summary, in this specification Appearance should not be construed as limiting the invention.
Finally it should be noted that:The preferred embodiments of the present invention are the foregoing is only, are not intended to limit the invention, Although the present invention is described in detail with reference to the foregoing embodiments, for those skilled in the art, it still may be used To be modified to the technical scheme described in foregoing embodiments, or equivalent substitution is carried out to which part technical characteristic, Within the spirit and principles of the invention, any modification, equivalent substitution and improvements made etc., should be included in the present invention's Within protection domain.

Claims (7)

1. a kind of heart and gallbladder deficiency of vital energy that improves causes the health products of insomnia, it is characterised in that be made up of the raw material of following proportion by weight: 10-20 parts of spina date seed, 5-20 parts of keel, 5-20 parts of plantain seed, 2-10 parts of Poria cocos, 2-10 parts of the fruit of Chinese magnoliavine, 2-10 parts of ginseng, radix glycyrrhizae 1-5 parts, 8-12 parts of maltodextrin;
Its preparation method is:
(1)Extract:The spina date seed of above-mentioned raw materials quality proportioning, keel, plantain seed, Poria cocos, the fruit of Chinese magnoliavine, ginseng, radix glycyrrhizae are taken, plus is steamed Distilled water refluxing extraction, Extracting temperature is 90-100 DEG C, and the water of 500-540g weight is added for the first time, after extracting 1.5-2.5 hours, The water of second of addition 410-440g weight, is extracted 0.5-1.5 hours;
(2)Filtering merges extract solution, and density is concentrated under reduced pressure under conditions of 60-80 DEG C for 1.05-1.25g/ml, adds and states original Expect the maltodextrin of quality proportioning, continue to be concentrated under reduced pressure into drying, take out, be ground into fine powder with pulverizer;
(3)Load capsule by every 0.2-0.6g, you can be made.
2. a kind of heart and gallbladder deficiency of vital energy that improves according to claim 1 causes the health products of insomnia, it is characterised in that by following matter Measure the raw material composition of part proportioning:It is 10 parts of spina date seed, 5 parts of keel, 5 parts of plantain seed, 2 parts of Poria cocos, 2 parts of the fruit of Chinese magnoliavine, 2 parts of ginseng, sweet Careless 1 part, 8 parts of maltodextrin.
3. a kind of heart and gallbladder deficiency of vital energy that improves according to claim 1 causes the health products of insomnia, it is characterised in that by following matter Measure the raw material composition of part proportioning:20 parts of spina date seed, 20 parts of keel, 20 parts of plantain seed, 10 parts of Poria cocos, 10 parts of the fruit of Chinese magnoliavine, ginseng 10 Part, 5 parts of radix glycyrrhizae, 12 parts of maltodextrin.
4. a kind of heart and gallbladder deficiency of vital energy that improves according to claim 1 causes the health products of insomnia, it is characterised in that:By following matter Measure the raw material composition of part proportioning:15 parts of spina date seed, 10 parts of keel, 10 parts of plantain seed, 5 parts of Poria cocos, 5 parts of the fruit of Chinese magnoliavine, 5 parts of ginseng, 2 parts of radix glycyrrhizae, 10 parts of maltodextrin.
5. a kind of heart and gallbladder deficiency of vital energy that improves according to claim 1 causes the health products of insomnia, it is characterised in that:The step (1)Middle Extracting temperature is 95 DEG C, and the water of 520g weight is added for the first time, is extracted 2 hours, and the water of 416g weight is added for the second time, Extract 1 hour.
6. a kind of heart and gallbladder deficiency of vital energy that improves according to claim 1 causes the health products of insomnia, it is characterised in that:The step (2)It is 1.15 that density is concentrated under reduced pressure under conditions of 70 DEG C.
7. a kind of heart and gallbladder deficiency of vital energy that improves according to claim 1 causes the health products of insomnia, it is characterised in that:The step (3)In every 0.4g load capsule.
CN201710486293.2A 2017-06-23 2017-06-23 A kind of heart and gallbladder deficiency of vital energy that improves causes health products of insomnia and preparation method thereof Pending CN107281308A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102940768A (en) * 2012-09-03 2013-02-27 吉林一正药业集团有限公司 Composition for improving sleep and preparation method and application thereof
CN105031216A (en) * 2015-08-21 2015-11-11 邱惠玲 Pharmaceutical composition for treating insomnia caused by deficiency of heart-qi and gallbladder-qi, honeyed pill and preparation method of honeyed pill

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102940768A (en) * 2012-09-03 2013-02-27 吉林一正药业集团有限公司 Composition for improving sleep and preparation method and application thereof
CN105031216A (en) * 2015-08-21 2015-11-11 邱惠玲 Pharmaceutical composition for treating insomnia caused by deficiency of heart-qi and gallbladder-qi, honeyed pill and preparation method of honeyed pill

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
马月香: "张珍玉治疗不寐案 ", 《山东中医杂志》 *

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