CN107280684B - Multistage scattering focusing blood parameter monitoring device - Google Patents
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- 239000008280 blood Substances 0.000 title claims abstract description 42
- 210000004369 blood Anatomy 0.000 title claims abstract description 42
- 238000012806 monitoring device Methods 0.000 title claims abstract description 12
- 238000012545 processing Methods 0.000 claims abstract description 22
- 238000004458 analytical method Methods 0.000 claims abstract description 17
- 239000000126 substance Substances 0.000 claims abstract description 9
- 238000007405 data analysis Methods 0.000 claims abstract description 8
- 230000003287 optical effect Effects 0.000 claims description 19
- 230000001105 regulatory effect Effects 0.000 claims description 8
- 238000006243 chemical reaction Methods 0.000 claims description 3
- 239000002131 composite material Substances 0.000 claims description 2
- 238000012544 monitoring process Methods 0.000 abstract description 35
- 238000001514 detection method Methods 0.000 abstract description 8
- 210000001742 aqueous humor Anatomy 0.000 description 19
- 210000001508 eye Anatomy 0.000 description 10
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 9
- 239000008103 glucose Substances 0.000 description 9
- 238000000034 method Methods 0.000 description 9
- 230000008859 change Effects 0.000 description 8
- 230000007547 defect Effects 0.000 description 5
- 230000006870 function Effects 0.000 description 5
- 230000003993 interaction Effects 0.000 description 5
- 230000036541 health Effects 0.000 description 4
- 206010012601 diabetes mellitus Diseases 0.000 description 3
- 201000001421 hyperglycemia Diseases 0.000 description 3
- 208000013016 Hypoglycemia Diseases 0.000 description 2
- 230000003542 behavioural effect Effects 0.000 description 2
- 238000004159 blood analysis Methods 0.000 description 2
- 230000003111 delayed effect Effects 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000002218 hypoglycaemic effect Effects 0.000 description 2
- 238000013507 mapping Methods 0.000 description 2
- 230000008520 organization Effects 0.000 description 2
- 230000008447 perception Effects 0.000 description 2
- 238000000554 physical therapy Methods 0.000 description 2
- 230000001360 synchronised effect Effects 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
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- 239000007788 liquid Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
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Abstract
The invention relates to a multistage scattering focusing regulation and control blood parameter monitoring device, a light source driving module drives a light source array to emit light fields with different wavelengths, a wavefront phase controller and a light field focusing part are sequentially arranged on the light path of the emergent light field of the light source array, an array photoelectric sensor is arranged on the emergent light path of the multistage scattering light field, the array photoelectric sensor converts photoelectric information of the detected light field containing monitored substance information and inputs the photoelectric information into a system control part, and the three parts of the wavefront phase controller, the array photoelectric sensor and the system control part form a dynamic control loop to realize multistage scattering focusing regulation and control; the system control part is connected with the information analysis processing part, and the information analysis processing part performs data analysis processing on the stabilized photoelectric information to obtain blood parameter index data. The invention has the characteristics of controllable detection area, high monitoring precision, real-time dynamic performance, good consistency, strong anti-interference performance, high reliability, wide application range, strong flexibility, easy function expansion and the like.
Description
Technical Field
The invention relates to a noninvasive blood parameter monitoring device, in particular to a multistage scattering focusing regulation and control blood parameter monitoring device applied to the fields of blood examination, health management, health monitoring, disease physiotherapy, life science, medical diagnosis, biotechnology, human-computer interaction, behavioral organization, intelligent perception and the like, and belongs to the technical field of noninvasive blood parameter monitoring.
Background
The noninvasive blood parameter monitoring has important academic research significance and wide practical application value in the fields of blood examination, health management, health monitoring, disease physiotherapy, life science, medical diagnosis, biotechnology, human-computer interaction, behavioral organization, intelligent perception and the like. Taking diabetes as an example, china has become the country with the largest number of people suffering from diabetes, and about 1.2 hundred million people are involved according to network information. Diabetes is a group of metabolic diseases characterized by hyperglycemia, which is caused by defective insulin secretion or impaired biological action, or both, and the long-term presence of hyperglycemia may lead to chronic damage, dysfunction, etc. of various tissues, especially eyes, kidneys, heart, blood vessels, nerves. The noninvasive monitoring method for the blood glucose index greatly promotes the index monitoring and tracking behavior of the hyperglycemia patient, improves the user experience and psychological comfort level, and has wide application value.
There are various non-invasive blood parameter monitoring devices in the prior art, see U.S. patent No. Apparatus for non-invasive glucose monitoring, issued patent number US9662004B2, patent grant time 2017, month 05, 30, proprietary to taiwan biophotonic company (Taiwan Biophotonic Corporation). The prior art and products have considerable advantages, but there are some essential disadvantages: 1) By adopting the detection principle of detecting the optical rotation characteristic of the aqueous humor of the eye, the content of sugar components in the aqueous humor of the eye and the content of sugar components in blood are not the same index, mapping conversion is needed, the monitoring precision and consistency are limited, monitoring errors exist, and the further improvement is difficult; 2) The change of the sugar content of aqueous humor and the change of the sugar content in blood are not synchronous, and the change of the blood sugar concentration in aqueous humor is delayed for a minute in time compared with the change of the blood sugar concentration in blood, so that the aqueous humor is difficult to be applicable to the detection of the occurrence of hypoglycemia, influences the application range and cannot dynamically monitor the blood sugar in real time; 3) The aqueous humor has anterior aqueous humor and posterior aqueous humor, the middle is separated by a part by iris, that is, the difference of the incident light system can lead to the possibility that the measured glucose concentration is the glucose concentration of the anterior aqueous humor, and the interference of the glucose in the posterior aqueous humor is also possible, the monitoring consistency and accuracy are influenced, and the high-consistency and high-accuracy monitoring cannot be realized; 4) In order to protect eyes, only very limited light energy is injected into the eyes, the monitoring flexibility is poor, the application range is limited, the user experience is weak, and the functions are difficult to expand.
Disclosure of Invention
The invention aims to overcome the defects of the technology and provide a multistage scattering focusing regulation and control blood parameter monitoring device which has the characteristics of simple method, controllable detection area, high monitoring precision, real-time dynamic performance, good consistency, strong anti-interference performance, high reliability, wide application range, strong flexibility, easy function expansion and the like.
In order to achieve the above purpose, the technical scheme of the invention is as follows: a multi-stage scatter focusing regulatory blood parameter monitoring device comprising: the system comprises a light field focusing component, a wavefront phase controller, a light source array, a light source driving module, an array type photoelectric sensor, a system control component and an information analysis processing component, wherein the light source array is connected with the light source driving module, and the light source driving module drives the light source array to emit light fields with different wavelengths and carries out frequency modulation on the light emission of each wavelength so as to realize multi-wavelength multi-modulation frequency output of the light source array; the system comprises a light source array emergent light field optical path, a wavefront phase controller, a light field focusing component, a multi-stage scattering light field emergent optical path, a system control component, a dynamic control loop, a multi-stage scattering focusing regulation and control component, wherein the wavefront phase controller and the light field focusing component are sequentially arranged on the light source array emergent light field optical path; the system control part is connected with the information analysis processing part, and the information analysis processing part performs data analysis processing on the stabilized photoelectric information to obtain blood parameter index data.
The monitored part is one of an arm part, a palm part, a leg part and a neck part.
The light source array is one of a multi-wavelength diode laser array, a multi-wavelength light emitting diode array and a light source of a broad spectrum light source composite narrow-band filter.
The array type photoelectric sensor is an integrated array type photoelectric sensor formed by an array type photoelectric sensor element and a converging optical system.
The beneficial effects of the invention are as follows:
the invention is based on the multistage scattering focusing principle, utilizes the wave-front phase regulation technology of the light field to realize multi-wavelength light field focusing, irradiates the detected area, carries out photoelectric information acquisition by the array photoelectric sensor, and associates the photoelectric information with wave-front phase regulation to form a dynamic loop, so that the light field characteristics of the monitored area can be regulated and controlled and the dynamic selection of the monitored area can be realized, the full interaction between the light field and the detected substance can be improved, and the information analysis processing component carries out data analysis on the photoelectric information data after stable monitoring to obtain the noninvasive blood parameter monitoring result.
Compared with the prior art, the invention has the following characteristics:
1) The prior art and the product have considerable advantages, but have some essential defects, adopt the detection principle of detecting the optical rotation characteristic of the aqueous humor of the eye, the content of sugar components in the aqueous humor of the eye and the content of sugar components in blood are not the same index, need to perform mapping conversion, have limited monitoring precision and consistency, have monitoring errors, and are difficult to further improve. The invention is based on the multistage scattering focusing principle, utilizes the optical field wavefront phase regulation and control technology to realize multi-wavelength optical field focusing, irradiates a detected area, performs photoelectric information acquisition by an array photoelectric sensor, performs data analysis on photoelectric information data after stable monitoring by an information analysis processing component, and obtains a noninvasive blood parameter monitoring result, and has the characteristics of simple method, high monitoring precision, real-time monitoring, good consistency, strong anti-interference performance, high reliability and the like;
2) The content of the sugar component in aqueous humor of eyes in the prior art is not synchronous with the change of the content of the sugar component in blood, and the change of the blood sugar concentration in aqueous humor is delayed by a time minute compared with the change of the blood sugar concentration in blood, so that the method is difficult to be applied to the detection of the occurrence of hypoglycemia, affects the application range and cannot dynamically monitor the blood sugar in real time. The invention monitors by utilizing the interaction of the light field and the blood parameters, dynamically correlates the change of the sugar component content in the liquid with the photoelectric information in the method dynamic method in real time, and correlates the photoelectric information with the wave front phase regulation to form a dynamic loop, so that the light field characteristics of a monitored area can be regulated and controlled and the dynamic selection of the monitored area can be realized, the full interaction of the light field and the detected substance can be improved, and the detection device is only required to be placed in the detected area when the detection device is used, thereby having the characteristics of wide application range, strong flexibility, easy function expansion, wide application range, good psychological comfort, strong user experience and the like;
3) The prior art aqueous humor has anterior aqueous humor and posterior aqueous humor, the middle of which is separated by a part by iris, that is, the difference of incident light systems can lead to the possibility that the measured glucose concentration is the glucose concentration of the anterior aqueous humor, and the measured glucose concentration is also possibly interfered by the glucose in the posterior aqueous humor, so that the monitoring consistency and accuracy are affected, and the high-consistency and high-accuracy monitoring cannot be realized. The invention fully utilizes the non-invasive blood parameter monitoring principle of photoelectric information, can perform blood multi-parameter dynamic real-time monitoring, has standard framework and modularized foundation, and has the characteristics of high anti-interference performance, high reliability, high consistency and the like;
4) In order to protect eyes, the prior art has the defects of poor monitoring flexibility, limited application range, weak user experience and difficult function expansion because only very limited light energy is injected into eyes. The invention detects on the skin of personnel, such as arms, back of hand and the like, and has the characteristics of no wound, no pain, flexible use, safety and the like.
Drawings
FIG. 1 is a schematic diagram of a multi-stage scattering focus control blood parameter monitoring device according to the present invention.
Detailed Description
The invention will now be further described with reference to the drawings and examples.
As shown in fig. 1, the multi-stage scattering focusing regulation blood parameter monitoring device of the present invention includes: the device comprises a light field focusing component 2, a wavefront phase controller 3, a light source array 4, a light source driving module 5, an array type photoelectric sensor 6, a system control component 7 and an information analysis processing component 8.
The light source array 4 is connected with the light source driving module 5, and the light source driving module 5 drives the light source array 4 to emit light fields with different wavelengths, and carries out frequency modulation on the light emission of each wavelength, so that the multi-wavelength multi-modulation frequency output of the light source array 4 is realized; the wavefront phase controller 3 and the light field focusing component 2 are sequentially arranged on the light path of the emergent light field of the light source array 4, the wavefront phase controller 3 regulates the wavefront phase of the emergent light field of the light source array 4, and the emergent light field passes through the light field focusing component 2 and irradiates the monitored part 1; the optical field of the area of the monitoring part 1 interacts with the detected substance, an array type photoelectric sensor 6 is arranged on the emergent optical path of the multistage scattering optical field, the array type photoelectric sensor 6 converts the optical field detected to contain the information of the detected substance and inputs the optical field into a system control component 7, the system control component 7 is connected with a wavefront phase controller 3, and the wavefront phase controller 3, the array type photoelectric sensor 6 and the system control component 7 form a dynamic control loop to realize multistage scattering focusing regulation and control; the system control part 7 and the information analysis processing part 8, the information analysis processing part 8 performs data analysis processing on the stabilized photoelectric information to obtain blood parameter index data.
In the embodiment, the monitored part 1 is the inner side of the arm; the light source array 4 is a multi-wavelength diode laser array, and coexists at four wavelengths, 2 are visible light wave band wavelengths, and 2 are infrared wave band wavelengths; the array type photoelectric sensor 6 adopts a CMOS area array sensor array; the system control part 7 adopts an FPGA and DSP framework; the information analysis processing section 8 adopts an FPGA architecture.
The working process of the embodiment is as follows: the light source driving module 5 drives the light source array 4 to emit light fields with different wavelengths, and carries out frequency modulation on the light emission of each wavelength, so that the multi-wavelength multi-modulation frequency output of the light source array 4 is realized; the wavefront phase controller 3 regulates the wavefront phase of the emergent light field of the light source array 4, and irradiates the monitored part 1 after passing through the light field focusing component 2; the optical field of the area of the monitoring part 1 interacts with the detected substance, an array type photoelectric sensor 6 is arranged on the emergent optical path of the multistage scattering optical field, the array type photoelectric sensor 6 converts the photoelectric information of the optical field which is detected to contain the information of the detected substance and inputs the optical field into a system control component 7, and a dynamic control loop is formed by the wavefront phase controller 3, the array type photoelectric sensor 6 and the system control component 7 so as to realize multistage scattering focusing regulation and control; the system control part 7 and the information analysis processing part 8, the information analysis processing part 8 performs data analysis processing on the stabilized photoelectric information to obtain blood parameter index data. The embodiment successfully realizes the multi-parameter monitoring of blood oxygen and blood sugar in blood and overcomes the defects of the prior art.
The invention is characterized in that based on the multistage scattering focusing principle, the multi-wavelength light field focusing is realized by utilizing the light field wave-front phase regulating technology, the photoelectric information is collected by the array photoelectric sensor, the photoelectric information and wave-front phase regulating and controlling are related to form a dynamic loop, the light field characteristics of a monitored area can be regulated and controlled, the dynamic selection of the monitored area is realized, the information analysis processing component carries out data analysis on the photoelectric information data after stable monitoring to obtain a noninvasive blood parameter monitoring result, and the noninvasive blood parameter monitoring method is simple in method, high in monitoring precision, dynamic monitoring, good in consistency, strong in anti-interference performance, high in reliability, wide in application range, strong in flexibility and easy to expand functions, and the defects of the prior art are essentially avoided.
The foregoing detailed description of the invention has outlined rather broadly the more detailed description of the invention in order that the present embodiment may be better understood, and the present embodiment may be utilized in the context of the present invention.
Claims (2)
1. A multi-stage scatter focusing regulatory blood parameter monitoring device comprising: the device comprises a light field focusing component (2), a wavefront phase controller (3), a light source array (4), a light source driving module (5), an array photoelectric sensor (6), a system control component (7) and an information analysis processing component (8), and is characterized in that: the light source array (4) is connected with the light source driving module (5), the light source driving module (5) drives the light source array (4) to emit light fields with different wavelengths, and frequency modulation is carried out on the light emission of each wavelength, so that multi-wavelength multi-modulation frequency output of the light source array (4) is realized; a wavefront phase controller (3) and a light field focusing component (2) are sequentially arranged on a light path of an emergent light field of the light source array (4), the wavefront phase controller (3) is used for carrying out wavefront phase regulation and control on the emergent light field of the light source array (4), the emergent light field passes through the light field focusing component (2) and irradiates the monitored part (1) to enable the regional light field of the monitored part (1) to interact with a detected substance, an array photoelectric sensor (6) is arranged on the multistage scattered light field emergent light path, the array photoelectric sensor (6) is used for inputting the detected light field containing the information of the detected substance into a system control component (7) after photoelectric information conversion is carried out, the system control component (7) is connected with the wavefront phase controller (3), and the wavefront phase controller (3), the array photoelectric sensor (6) and the system control component (7) form a dynamic control loop to realize multistage scattering focusing regulation and control; the system control part (7) is connected with the information analysis processing part (8), and the information analysis processing part (8) performs data analysis processing on the stabilized photoelectric information to obtain blood parameter index data; the array type photoelectric sensor (6) is an integrated array type photoelectric sensor formed by an array type photoelectric sensor element and a converging optical system; the light source array (4) is one of a multi-wavelength diode laser array, a multi-wavelength light emitting diode array and a light source of a broad spectrum light source composite narrow-band filter.
2. The multi-stage scatter focusing regulatory blood parameter monitoring device of claim 1, wherein: the monitored part (1) is one of an arm part, a palm part, a leg part and a neck part.
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Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101264019A (en) * | 2007-03-16 | 2008-09-17 | 北京中科光睿科技有限责任公司 | Novel portable non-invasive, continuous, real time blood sugar monitoring instrument based on light sound technique |
| CN101278874A (en) * | 2007-12-28 | 2008-10-08 | 中国科学院光电技术研究所 | Transmission type artificial crystal aberration Hartmann measuring instrument |
| CN101467884A (en) * | 2007-12-28 | 2009-07-01 | 中国科学院电子学研究所 | Non-invasive method and device for rapidly detecting blood sugar |
| CN105537760A (en) * | 2016-01-12 | 2016-05-04 | 上海理工大学 | Controllable laser processing device based on wavefront modulation |
| CN105979860A (en) * | 2014-09-09 | 2016-09-28 | 皇家飞利浦有限公司 | Vital signs monitoring system |
| CN106950195A (en) * | 2017-02-24 | 2017-07-14 | 西安电子科技大学 | Programmable optical elements and light field regulator control system and method based on scattering medium |
| CN208447606U (en) * | 2017-07-20 | 2019-02-01 | 上海理工大学 | Order Scattering focuses regulation blood parameters monitoring device |
-
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- 2017-07-20 CN CN201710595935.2A patent/CN107280684B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101264019A (en) * | 2007-03-16 | 2008-09-17 | 北京中科光睿科技有限责任公司 | Novel portable non-invasive, continuous, real time blood sugar monitoring instrument based on light sound technique |
| CN101278874A (en) * | 2007-12-28 | 2008-10-08 | 中国科学院光电技术研究所 | Transmission type artificial crystal aberration Hartmann measuring instrument |
| CN101467884A (en) * | 2007-12-28 | 2009-07-01 | 中国科学院电子学研究所 | Non-invasive method and device for rapidly detecting blood sugar |
| CN105979860A (en) * | 2014-09-09 | 2016-09-28 | 皇家飞利浦有限公司 | Vital signs monitoring system |
| CN105537760A (en) * | 2016-01-12 | 2016-05-04 | 上海理工大学 | Controllable laser processing device based on wavefront modulation |
| CN106950195A (en) * | 2017-02-24 | 2017-07-14 | 西安电子科技大学 | Programmable optical elements and light field regulator control system and method based on scattering medium |
| CN208447606U (en) * | 2017-07-20 | 2019-02-01 | 上海理工大学 | Order Scattering focuses regulation blood parameters monitoring device |
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