CN106037760A - Continuous blood glucose monitoring system of noninvasive glucometer - Google Patents

Continuous blood glucose monitoring system of noninvasive glucometer Download PDF

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Publication number
CN106037760A
CN106037760A CN201610510859.6A CN201610510859A CN106037760A CN 106037760 A CN106037760 A CN 106037760A CN 201610510859 A CN201610510859 A CN 201610510859A CN 106037760 A CN106037760 A CN 106037760A
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CN
China
Prior art keywords
module
monitoring system
blood glucose
continuous blood
glucose monitoring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610510859.6A
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Chinese (zh)
Inventor
祝翔
冯吉昌
蒋特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wuhan Ming Chuang Ke Technology Co Ltd
Original Assignee
Wuhan Ming Chuang Ke Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wuhan Ming Chuang Ke Technology Co Ltd filed Critical Wuhan Ming Chuang Ke Technology Co Ltd
Priority to CN201610510859.6A priority Critical patent/CN106037760A/en
Publication of CN106037760A publication Critical patent/CN106037760A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14552Details of sensors specially adapted therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7225Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/74Details of notification to user or communication with user or patient ; user input means
    • A61B5/746Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms

Abstract

The invention discloses a continuous blood glucose monitoring system of a noninvasive glucometer. The monitoring system comprises a hardware system and a software system, wherein the hardware system comprises a near-infrared light source module, a finger, a detection module, an A/D (analog-to-digital conversion) unit, a control and computing module and a display module; and the software system comprises a mobile phone APP application, a database and a third party guardian. The continuous blood glucose monitoring system of the noninvasive glucometer can implement real-time continuous tests on the glucose concentration of a patient in a noninvasive monitoring mode, and the continuous blood glucose monitoring system, which can avoid blood collection, can reduce risk of wound infection in patients with diabetics; besides the patients with the diabetics, other potential groups focusing on their health can closely master their glycemic indexes by virtue of the product (the continuous blood glucose monitoring system); the continuous blood glucose monitoring system, in coordination with movement schemes and diet schemes, can achieve the significance of preventing the diabetics and other chronic metabolic diseases; the continuous blood glucose monitoring system can avoid trauma and consumables, and can achieve better advanced interfere treatment on patients in a prediabetic state; and the continuous blood glucose monitoring system, in coordination with rehabilitation messages, can reduce a disease risk.

Description

A kind of continuous blood sugar monitoring system of non-invasive blood sugar instrument
Technical field
The present invention relates to field of medical technology, the continuous blood sugar monitoring system of a kind of non-invasive blood sugar instrument.
Background technology
The most biochemical blood glucose measurement method of current blood sugar measuring method and Wicresoft's blood sugar test method.Biochemical blood sugar test method The most ripe with the technology of Wicresoft blood sugar test method, also it is the main method of current blood glucose measurement, but these two kinds of measuring methods are all Need to take blood examination to survey, owing to blood drawing or finger acupuncture treatment take blood and can cause pain, and have the danger of infection, which limits mensuration The frequency of blood glucose, makes diabetics cannot obtain satisfied blood sugar monitoring, therefore in the urgent need to taking non-invasive blood glucose measurement Technology overcomes the shortcoming that invasive blood sampling continuous blood sugar is monitored.
Summary of the invention
It is an object of the invention to provide the continuous blood sugar monitoring system of a kind of non-invasive blood sugar instrument, to solve invasive blood sampling The shortcoming of continuous blood sugar monitoring.
For achieving the above object, the present invention provides following technical scheme: the continuous blood sugar monitoring of a kind of non-invasive blood sugar instrument is System, including hardware system and software system, described hardware system includes that near infrared light source module, finger, detection module, A/D are mono- Unit, control and computing module and display module, described software system includes the application of mobile phone A PP, data base and third party guardian, Described control is bi-directionally connected with infrared light supply module with computing module, and infrared light supply module is connected with finger, finger and detection mould Block connects, and the outfan of detection module is connected with the input of A/D unit, and described control and computing module are two-way with detection module Connecting, described control is bi-directionally connected with A/D unit with computing module, described control and the first outfan of computing module and display The input of module connects.
Control in described hardware system is applied with mobile phone A PP that includes in software system with the second outfan of computing module Input by bluetooth wireless connections, the outfan of described mobile phone A PP application is connected with the input of data base, data base's Outfan is connected with third party guardian.
Preferably, described near infrared light source module is LED light source module.
Compared with prior art, the method have the advantages that
(1), the continuous blood sugar of the non-invasive blood sugar instrument of the present invention monitors system, by the noninvasive monitoring mode Portugal to patient Grape sugar concentration carries out the most continuous continual test, it is not necessary to blood sampling, reduces the risk of diabetics wound infection, is suitable for Crowd is not limited to diabetics, and other pays close attention to the potential colony of own blood glucose, all can closely understand self by this product Glycemic index, routing motion scheme, diet program reach to prevent diabetes and the meaning of other chronic metabolic disease.
(2), the continuous blood sugar of the non-invasive blood sugar instrument of the present invention monitors system, by the noninvasive monitoring mode Portugal to patient Grape sugar concentration carries out the most continuous continual test, it is not necessary to wound, it is not necessary to consumptive material, and pre-diabetic preferably shifts to an earlier date Therapeutic intervention, coordinates rehabilitation information, reduces risk.
Accompanying drawing explanation
Fig. 1 is present configuration schematic diagram.
Detailed description of the invention
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is carried out clear, complete Describe, it is clear that described embodiment is only a part of embodiment of the present invention rather than whole embodiments wholely.Based on Embodiment in the present invention, it is every other that those of ordinary skill in the art are obtained under not making creative work premise Embodiment, broadly falls into the scope of protection of the invention.
Referring to Fig. 1, the present invention provides a kind of technical scheme: the continuous blood sugar of a kind of non-invasive blood sugar instrument monitors system, bag Include hardware system and software system, hardware system include near infrared light source module, finger, detection module, A/D unit, control with Computing module and display module, software system includes the application of mobile phone A PP, data base and third party guardian, controls and calculates mould Block is bi-directionally connected with infrared light supply module, and infrared light supply module is connected with finger, and finger is connected with detection module, in detection module It is provided with gravity sensing module, segments specific wavelength to each sensor according to the sensor array of design, then through detection Model algorithm merges the information of each sensor, calibrates blood glucose information, and the information so collected is the most comprehensively, in order to from respectively Kind of attenuation factor, as the spectrum of the blood components such as moisture content, skin, blood, albumen extracts enough signals, effectively measuring go out Blood sugar concentration, by the gravity sensing module that this system is built-in, the motion conditions of record user, goes out user's by algorithm simulation Calorie Expenditure Levels, in conjunction with blood glucose fluctuation, feeds back to one optimum guidance of user, and the outfan of detection module is mono-with A/D The input of unit connects, and controls to be bi-directionally connected with detection module with computing module, controls and computing module and the two-way company of A/D unit Connect, control to be connected with the input of display module with the first outfan of computing module.
Control in hardware system and the second outfan of computing module with include the defeated of mobile phone A PP application in software system Entering end by bluetooth wireless connections, the outfan of mobile phone A PP application is connected with the input of data base, the outfan of data base and Third party guardian is connected.
This system mainly penetrates tissue by the characteristic of near infrared light, obtains multiple signals, sensor array Interval gathers the blood glucose of tissue different wave length several times and absorbs information to respective passage, the generation signal of telecommunication, it is achieved photoelectricity turns Change, complete array sampling, the signal of telecommunication that the photosensor arrays in each multi-channel photodetector module produces, be sent to multichannel The amplifier of preposition hardware system is amplified, filters, Integral Processing, make signal reach amplitude and signal to noise ratio that detection identifies, The analogue signal transformation to digital signal, the numeral after conversion is realized again by the A/D converter in the A/D unit in hardware system Signal is delivered to software system and is obtained microprocessor and carry out the process of array signal, finally exports blood glucose value, then by controlling and meter Calculating module, calculate the blood glucose value of target, in order to make the monitoring of equipment time more long, this system uses and have adjusted noinvasive blood accordingly The detection frequency of the continuous blood sugar monitoring system of sugar instrument, completes one-time detection task in 5 minutes, while ensureing monitoring purpose, Extend the working time of the equipment after single charge.Compare tradition and have invasive blood sugar instrument, be a time period with 24 hours, noinvasive blood The pendulous frequency of the continuous blood sugar monitoring system of sugar instrument 288 times, and be 1 to 3 times according to traditional invasive blood sugar instrument measurement custom that has, Measuring frequency the highest, the meaning of monitoring is the strongest, and therefore the continuous blood sugar monitoring system of non-invasive blood sugar instrument has unrivaled company Continuous monitoring advantage, it is not necessary to blood sampling, reduces the risk of diabetics wound infection, and applicable crowd is not limited to diabetics, its It pays close attention to the potential colony of own blood glucose, all can closely be understood the glycemic index of self, routing motion scheme, drink by this product Food scheme reaches to prevent diabetes and the meaning of other chronic metabolic disease, it is not necessary to wound, it is not necessary to consumptive material, prediabetes Patient preferably shifts to an earlier date therapeutic intervention, coordinates rehabilitation information, reduces risk.
Operation principle: continuous blood sugar monitoring system the most hundreds of blood glucose of 24 hours follow-on test records of this non-invasive blood sugar instrument Data, 5min tests once, and continuous blood sugar monitoring is to be carried out the concentration of glucose of patient in real time by noninvasive monitoring mode The continuous continual test in ground, and continue the suitable time, as long as glucose is blood glucose composition, glucose molecule contains -OH ,-CH ,-C=O have strong absorption near infrared region, and glucose is widely distributed in tissue and blood, when closely Infrared light is absorbed and is scattered when entering tissue, and emergent light is to comprise diffusing of tissue Multiple components information Spectrum, uses energy absorption and the reflection of the multiple near-infrared wavelength of commercial measurement of multicomponent analysis, due to glucose and other composition Only absorb and reflect the sub-fraction of each wavelength, and various different chemical composition is in the absorption of certain wave band and reflection Intensity different, therefore measure and demarcate the spectral absorption reflected value of each wavelength, by training algorithm, reach detect blood The purpose of sugar concentration, ultimately forms a kind of novel blood sugar detecting method of continuous print blood glucose collection of illustrative plates, same to mobile phone, computer can connect machine Draw blood glucose dynamic curve diagram, it is provided that the visual information of glucose change, it is possible to find without the hypoglycemia period of Signs, can determine that After dining, glucose peak value directly instructs or adjusts therapeutic scheme, decorum statistical data accurately and reliably, such as overall glycemic Meansigma methods, odd-numbered day blood glucose meansigma methods, post-prandial glycemia meansigma methods, just plasma glucose time ratio, blood glucose fluctuation coefficient etc., can be insulin The dosage form dosage of therapy provides dynamic evaluation, and the sieving and diagnosis of diabetes provides more convenient reliable method, can be that diabetes are treated Effect and different blood glucose levels provide and facilitate reliable evaluation measures, and the research measured the most continuously is higher, non-invasive blood sugar instrument Continuous blood sugar monitoring system retains patient's all of Historical Monitoring record, and medical personnel pass through historical data, more fully understand The diabetes de-velopment situation of patient, when the blood glucose value of diabetics occurs in high risk zone, non-invasive blood sugar instrument continuous Blood glucose monitoring system can remind patient, takes measures at once, and pushes warning to third party guardian, and non-invasive blood sugar instrument The monitoring in real time of continuous blood sugar monitoring system has more preferable optimum feedback meaning, and patient is due to bad life habits or absorption Medicine or food unreasonable, the blood glucose value caused raises or declines, and all can feed back on blood glucose value patient one intuitively, Patient can evade harmful effect, conservative control blood glucose naturally.
In sum, the correlation module related in this system is hardware system module or for calculating in prior art The functional module that machine software program or agreement combine with hardware, the computer software programs involved by this functional module or association The technology being well known to those skilled in the art of view itself, it is not the improvements of native system;Being improved to of this system is each Interaction relationship between module or annexation, be the overall structure to system and improve, to solve this system Relevant art problem to be solved.
Although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, permissible Understand and these embodiments can be carried out multiple change without departing from the principles and spirit of the present invention, revise, replace And modification, the scope of the present invention be defined by the appended.

Claims (2)

1. a continuous blood sugar monitoring system for non-invasive blood sugar instrument, including hardware system and software system, it is characterised in that: described Hardware system includes near infrared light source module, finger, detection module, A/D unit, controls and computing module and display module, institute State software system and include the application of mobile phone A PP, data base and third party guardian, described control and computing module and infrared light supply mould Block is bi-directionally connected, and infrared light supply module is connected with finger, and finger is connected with detection module, and the outfan of detection module is mono-with A/D The input of unit connects, and described control is bi-directionally connected with detection module with computing module, and described control is mono-with A/D with computing module Unit is bi-directionally connected, and described control is connected with the input of display module with the first outfan of computing module;
Control in described hardware system and the second outfan of computing module with include the defeated of mobile phone A PP application in software system Enter end to be connected with the input of data base by bluetooth wireless connections, the outfan of described mobile phone A PP application, the output of data base End is connected with third party guardian.
The continuous blood sugar monitoring system of a kind of non-invasive blood sugar instrument the most according to claim 1, it is characterised in that: described the reddest Outer light source module is LED light source module.
CN201610510859.6A 2016-06-30 2016-06-30 Continuous blood glucose monitoring system of noninvasive glucometer Pending CN106037760A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109965886A (en) * 2019-03-21 2019-07-05 邓庆平 A kind of hurtless measure Intelligent blood sugar measuring instrument
CN110680340A (en) * 2019-10-18 2020-01-14 吉林大学中日联谊医院 All-weather blood sugar monitoring system for diabetes health management
CN110960750A (en) * 2019-11-11 2020-04-07 云南大学 Intelligent Internet of things monitoring system and method for intravenous drip

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Publication number Priority date Publication date Assignee Title
CN2778199Y (en) * 2005-03-18 2006-05-10 西北工业大学 Portable non-invasive blood sugar monitoring instrument
CN101647703A (en) * 2009-08-10 2010-02-17 中卫莱康科技发展(北京)有限公司 Blood sugar real-time monitoring system and method, blood sugar detection device and mobile phone terminal
WO2012051018A2 (en) * 2010-10-15 2012-04-19 Novanex Inc. A method for non-invasive blood glucose monitoring
CN203861235U (en) * 2014-05-08 2014-10-08 广州双悠生物科技有限责任公司 Wireless blood oxygen saturation monitoring system device
CN105919569A (en) * 2016-05-25 2016-09-07 生命基云健康产业(湖南)有限公司 Health monitoring system

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2778199Y (en) * 2005-03-18 2006-05-10 西北工业大学 Portable non-invasive blood sugar monitoring instrument
CN101647703A (en) * 2009-08-10 2010-02-17 中卫莱康科技发展(北京)有限公司 Blood sugar real-time monitoring system and method, blood sugar detection device and mobile phone terminal
WO2012051018A2 (en) * 2010-10-15 2012-04-19 Novanex Inc. A method for non-invasive blood glucose monitoring
CN203861235U (en) * 2014-05-08 2014-10-08 广州双悠生物科技有限责任公司 Wireless blood oxygen saturation monitoring system device
CN105919569A (en) * 2016-05-25 2016-09-07 生命基云健康产业(湖南)有限公司 Health monitoring system

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109965886A (en) * 2019-03-21 2019-07-05 邓庆平 A kind of hurtless measure Intelligent blood sugar measuring instrument
WO2020187240A1 (en) * 2019-03-21 2020-09-24 邓庆平 Noninvasive intelligent blood glucose meter
CN113811243A (en) * 2019-03-21 2021-12-17 苏州优化医疗科技有限公司 Noninvasive intelligent blood glucose measuring instrument
CN110680340A (en) * 2019-10-18 2020-01-14 吉林大学中日联谊医院 All-weather blood sugar monitoring system for diabetes health management
CN110960750A (en) * 2019-11-11 2020-04-07 云南大学 Intelligent Internet of things monitoring system and method for intravenous drip

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Application publication date: 20161026