CN107261023A - 一种治疗湿疹的中药组合物及其制备方法 - Google Patents
一种治疗湿疹的中药组合物及其制备方法 Download PDFInfo
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- CN107261023A CN107261023A CN201710576432.0A CN201710576432A CN107261023A CN 107261023 A CN107261023 A CN 107261023A CN 201710576432 A CN201710576432 A CN 201710576432A CN 107261023 A CN107261023 A CN 107261023A
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Abstract
本发明属于中药制剂领域,目的是根据中医对湿疹的认识机理而提供的一种治疗湿疹的中药组合物,所述中药组合物的各个组分及其质量份比如下:荆芥3~12g、干地黄10~16g、野菊花10~16g、山药(炒)15~35g、炒黄苓5~18g、全虫4~8g、紫草5~16g、乌豆衣6~18g、苦参3~12g、陈皮3~16g、大青叶10~16g、马鞭草15~35g、黄柏8~16g、苡米10~35g、白鲜皮6~16g、蒲公英10~35g;本发明提供的药物是一个标本兼治的中药组方。
Description
技术领域
本发明属于中药制剂领域,具体涉及一种治疗湿疹的中药组合物,特别是供湿疹患者使用的中药组合物及其制备方法的领域。
背景技术
医者认为:湿疹是由多种内外因素引起的瘙痒剧烈的一种皮肤炎症反应。分急性、亚急性、慢性三期。急性期具渗出倾向,慢性期则浸润、肥厚。有些病人直接表现为慢性湿疹。皮损具有多形性、对称性、瘙痒和易反复发作等特点。
临床表现:
一、按皮损表现分为急性、亚急性、慢性三期。
1、急性湿疹 皮损初为多数密集的粟粒大小的丘疹、丘疱疹或小水疱,基底潮红,逐渐融合成片,由于搔抓,丘疹、丘疱疹或水疱顶端抓破后呈明显的点状渗出及小糜烂面,边缘不清。如继发感染,炎症更明显,可形成脓疱、脓痂、毛囊炎、疖等。自觉剧烈瘙痒。好发于头面、耳后、四肢远端、阴囊、肛周等,多对称发布。
2、亚急性湿疹 急性湿疹炎症减轻后,皮损以小丘疹、结痂和鳞屑为主,仅见少量丘疱疹及糜烂。仍有剧烈瘙痒。
3、慢性湿疹 常因急性、亚急性湿疹反复发作不愈而转为慢性湿疹;也可开始即为慢性湿疹。表现为患处皮肤增厚、浸润,棕红色或色素沉着,表面粗糙,覆鳞屑,或因抓破而结痂。自觉瘙痒剧烈。常见于小腿、手、足、肘窝、腘窝、外阴、肛门等处。病程不定,易复发,经久不愈。
二、根据皮损累及的范围,分为局限性湿疹和泛发性湿疹两大类。
1、局限性湿疹 仅发生在特定部位,即可以部位命名,如手部湿疹、女阴湿疹、阴囊湿疹、耳部湿疹、乳房湿疹、肛周湿疹、小腿湿疹等。
2、泛发性湿疹 皮损多,泛发或散发于全身多个部位。如钱币性湿疹、自身敏感性湿疹、乏脂性湿疹。
那么,就如何找到一种可有效治疗湿疹的中药组合物,是我们目前急需要解决的问题。
发明内容
随着我国中医中药学的不断发展,在治疗湿疹上,人们逐渐意识到了中医治疗湿疹的优点,且在治疗过程中疗效好、见效快、毒副作用小等优势,针对现有西医治疗湿疹的现状,本发明的目的是在于提供一种治疗湿疹的中药组合物,以解决湿疹患者早日恢复健康的问题。该药物是以常见的中药为原料,通过选择合理的药物及质量份比,可有效治疗上述湿疹。
为达到上述发明的目的,本发明所采用的技术方案为:提供一种治疗湿疹的中药组合物及其制备方法,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
荆芥3~12g、干地黄10~16g、野菊花10~16g、山药(炒)15~35g、炒黄苓5~18g、全虫4~8g、紫草5~16g、乌豆衣6~18g、苦参3~12g、陈皮3~16g、大青叶10~16g、马鞭草15~35g、黄柏8~16g、苡米10~35g、白鲜皮6~16g、蒲公英10~35g。
一种治疗湿疹的中药组合物及其制备方法,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
荆芥6~11g、干地黄11~14g、野菊花11~14g、山药(炒)17~31g、炒黄苓8~16g、全虫5~7g、紫草8~14g、乌豆衣8~16g、苦参6~11g、陈皮6~14g、大青叶11~14g、马鞭草18~31g、黄柏10~14g、苡米11~31g、白鲜皮8~14g、蒲公英11~31g。
一种治疗湿疹的中药组合物及其制备方法,其特征在于,所述“最佳方案”的中药组合物的各个组分及其质量份比如下所示:
荆芥10g、干地黄12g、野菊花12g、山药(炒)26g、炒黄苓14g、全虫6g、紫草12g、乌豆衣14g、苦参10g、陈皮12g、大青叶12g、马鞭草26g、黄柏12g、苡米26g、白鲜皮12g、蒲公英26g。
一种治疗湿疹的中药组合物及其制备方法,其特征在于,所述方法包括如下步骤制备而成:
A、将上述原料中药拣去杂质和粉尘后,按照质量份比分别粉碎成粗粒状包煎;
B、将包好的原料中药放入冷开水中浸泡半个小时,然后再将浸泡好的药物和浸泡药物的澄清液一并放入砂锅内,注入过药38mm的冷开水进行第一次煎煮50分钟,滤取药液后,再次注入过药33mm的微温开水进行第二次煎煮40分钟,二次混合浓缩成50%的中药液540毫升备用。
一种治疗湿疹的中药组合物及其制备方法,其特征在于,所述服用方法为:将制备好的中药液以一天服用,早中晚各服一次,给药量180毫升/次。服药7~28天,症状逐渐减轻或痊愈。
本发明组方中的各原料中药在中国药典、中国辞典以及中华本草中均有详细的记载。本发明选用其中最常见的中药为原料,充分发挥各组分的药理功效:
荆芥,性味:味辛、微苦、性微湿,具有祛风、解表、透疹、止血之功效,用于治疗感冒发热、头痛、目痒、咳嗽、咽喉肿痛、麻疹、痈肿、疮疥、衄血、吐血、便血、崩漏、产后血晕;
干地黄,性味:味甘、苦、微寒,具有滋阴清热、凉血补血之功效,用于治疗热病烦渴、内热消渴、骨蒸劳热、温病发斑、血热所致的吐血、崩漏、尿血、便血、血虚萎黄、眩晕心悸、血少经闭;
野菊花,性味:味苦、辛、性平,具有清热解毒、疏风平肝之功效,用于治疗清热解毒、疏风平肝、疔疮、痈疽、丹毒、湿疹、皮炎、风热感冒、咽喉肿痛、高血压;
山药(炒),性味:甘、平,具有健脾、补肺、固肾、益精之功效,用于治疗脾虚泄泻、久痢、虚劳咳嗽、消渴、遗精、带下、小便频数;另具补脾养胃、生津益肺、补肾涩精之功效,用于脾虚食少、久泻不止、肺虚喘咳、肾虚遗精、带下、尿频、虚热消渴;
炒黄苓,性味:味苦、性寒,具有清热燥湿、泻火解毒、止血、安胎之功效,而又因为炒黄芩的临床抗菌性较好,而且不产生抗药性,因此在临床上的应用广泛;
全虫,性味:咸辛、平,有毒,具有祛风、止痉、通络、解毒之功效,用于治疗惊风抽摘、癫痫、中风、半身不遂、口眼歪斜、偏头痛、风湿痹痛、破伤风、淋巴结结核、风疹疮肿;
紫草,性味:性平、味苦、辛,具有凉血、活血、清热、解毒之功效,用于治疗温热斑疹、湿热黄疸、紫癜、吐、衄、尿血、淋浊、热结便秘、烧伤、湿疹、丹毒、痈疡等症;
乌豆衣,性味:甘、平,具有养血祛风、养血补肾之功效,用于治疗血虚头痛、眩晕、耳鸣及阴虚盗汗;
苦参,性味:味苦、性寒,具有清热燥湿、祛风杀虫之功效,用于治疗湿热泻痢、肠风便血、黄疸、小便不利、水肿、带下、阴痒、疥癣、麻风、皮肤瘙痒、湿毒疮疡;
陈皮,性味:味辛、苦、性温,具有理气和中,燥湿化痰,利水通便之功效,用于治疗脾胃不和、脘腹胀痛、不思饮食、呕吐哕逆、痰湿阻肺、咳嗽痰多、胸膈满闷、头目眩晕、水肿、小便不利、大便秘结、乳痈疥癣、中鱼蟹毒、酒毒等;
白鲜皮,性味:苦咸、寒,具有祛风、燥湿、清热、解毒之功效,用于治疗风热疮毒、疥癣、皮肤痒疹、风湿痹痛、黄疸等症;
大青叶,性味:苦、寒,具有清热解毒、凉血消斑之功效,用于治疗热病高热烦渴、神昏、斑疹、吐血、衄血、黄疸、泻痢、丹毒、喉痹、口疮、痄腮等症;
马鞭草,性味:苦、辛、微寒,具有清热解毒、活血通经、利水消肿、截疟之功效,用于治疗感冒发热、咽喉肿痛、牙龈肿痛、黄疸、痢疾、血瘀经闭、痛经、癥瘕、水肿、小便不利、疟疾、痈疮肿毒、跌打损伤;
黄柏,性味:苦、寒,具有清热燥湿、泻火解毒之功效,用于治疗湿热痢疾、泄泻、黄疸、梦遗、淋浊、带下、骨蒸劳热、以及口舌生疮、目赤肿痛、痈疽疮毒、皮肤湿疹;
苡米,性味:甘、淡、微寒,具有利湿健脾、舒筋除痹、清热排脓之功效,用于治疗水肿、脚气、小便淋沥、湿温病、泄泻带下、风湿痹痛、筋脉拘挛、肺痈、肠痈、扁平疣;
白鲜皮,性味:苦、咸、寒,具有清热燥湿、祛风止痒、解毒之功效,用于治疗风热湿毒所致的风疹、湿疹、疥癣、黄疸、湿热 痹等症;
蒲公英,性味:味苦、甘、性寒,具有清热解毒、消痈散结之功效,用于治疗乳痈、肺痈、肠痈、痄腮、疔毒疮肿、目赤肿痛、感冒发热、咳嗽、咽喉肿痛、胃火、肠炎、痢疾、肝炎、胆吓炎、尿路感染、蛇虫咬伤。
本发明药物是基于中医治疗湿疹的原则,从药理作用及其作用机制认为:就湿疹,本发明所提供的药物中的各原料中药药效共奏,对上述疾病有很好的治疗效果。
具体实施方式
本发明就是针对上述湿疹的治疗而提出的一种中药配方,采用该配方制备的药物药效好,见效快,是一个标本兼治的中药组方,特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述:
实施例1:
一种治疗湿疹的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
荆芥10g、干地黄12g、野菊花12g、山药(炒)26g、炒黄苓14g、全虫6g、紫草12g、乌豆衣14g、苦参10g、陈皮12g、大青叶12g、马鞭草26g、黄柏12g、苡米26g、白鲜皮12g、蒲公英26g。
实施例2:
一种治疗湿疹的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
荆芥11g、干地黄14g、野菊花14g、山药(炒)31g、炒黄苓16g、全虫7g、紫草14g、乌豆衣16g、苦参11g、陈皮14g、大青叶14g、马鞭草31g、黄柏14g、苡米31g、白鲜皮14g、蒲公英31g。
实施例3:
一种治疗湿疹的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
荆芥12g、干地黄16g、野菊花16g、山药(炒)35g、炒黄苓18g、全虫8g、紫草16g、乌豆衣18g、苦参12g、陈皮16g、大青叶16g、马鞭草35g、黄柏16g、苡米35g、白鲜皮16g、蒲公英35g。
典型病例
经临床诊断治疗湿疹患者共705例,年龄为28岁以上的355例,只有350例为28岁以下。705例患者中痊愈的680例,显效的的25例,总有效率达100%。
Claims (3)
1.一种治疗湿疹的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
荆芥3~12g、干地黄10~16g、野菊花10~16g、山药(炒)15~35g、炒黄苓5~18g、全虫4~8g、紫草5~16g、乌豆衣6~18g、苦参3~12g、陈皮3~16g、大青叶10~16g、马鞭草15~35g、黄柏8~16g、苡米10~35g、白鲜皮6~16g、蒲公英10~35g。
2.根据权利要求1所述的治疗湿疹的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
荆芥6~11g、干地黄11~14g、野菊花11~14g、山药(炒)17~31g、炒黄苓8~16g、全虫5~7g、紫草8~14g、乌豆衣8~16g、苦参6~11g、陈皮6~14g、大青叶11~14g、马鞭草18~31g、黄柏10~14g、苡米11~31g、白鲜皮8~14g、蒲公英11~31g。
3.根据权利要求1至2所述的治疗湿疹的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
荆芥10g、干地黄12g、野菊花12g、山药(炒)26g、炒黄苓14g、全虫6g、紫草12g、乌豆衣14g、苦参10g、陈皮12g、大青叶12g、马鞭草26g、黄柏12g、苡米26g、白鲜皮12g、蒲公英26g。
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Application publication date: 20171020 |