CN107233551A - A kind of quick-acting water-honeyed pills of facial paralysis and preparation method thereof - Google Patents
A kind of quick-acting water-honeyed pills of facial paralysis and preparation method thereof Download PDFInfo
- Publication number
- CN107233551A CN107233551A CN201710516732.XA CN201710516732A CN107233551A CN 107233551 A CN107233551 A CN 107233551A CN 201710516732 A CN201710516732 A CN 201710516732A CN 107233551 A CN107233551 A CN 107233551A
- Authority
- CN
- China
- Prior art keywords
- parts
- portions
- decoction
- water
- facial paralysis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/646—Arachnids, e.g. spiders, scorpions, ticks or mites
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/648—Myriapods, e.g. centipedes or millipedes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/538—Schizonepeta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/884—Alismataceae (Water-plantain family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2068—Compounds of unknown constitution, e.g. material from plants or animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Botany (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Insects & Arthropods (AREA)
- Zoology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Cosmetics (AREA)
Abstract
The present invention relates to quick-acting water-honeyed pills of a kind of facial paralysis and preparation method thereof, according to weight ratio, the preparing raw material of the water-honeyed pill is made up of 15 20 parts of Radix Angelicae Sinensis, 20 25 parts of cassia twig, 20 25 parts of Ligusticum wallichiis, 25 30 parts of yncaria stems with hooks, 20 25 parts of centipedes, 15 20 portions of scorpios, 10 15 parts of monkshoods, 10 15 portions of rhizoma zingiberis, 20 25 parts of stiff silkworms, 10 15 portions of radix glycyrrhizaes, 15 20 portions of rhizoma alismatis, 10 20 portions of schizonepeta and the 10 20 parts of Poria cocos by processing.Quick-acting water-honeyed pills of facial paralysis of the present invention and preparation method thereof, facial paralysis symptom caused by a variety of causes is taken effect rapidly, 13 days symptoms are taken to can obviously relieve, being taken 12 weeks according to the state of an illness to fully recover, and effect is notable and rapid, it is adaptable to the patient of all age group, and water-honeyed pill is made in Chinese medicinal formulae, conveniently take, the pain of patient's medication is alleviated, while being easy to mass production to promote.
Description
Technical field
The invention belongs to Chinese medicine preparation field, the quick-acting water-honeyed pills of specially a kind of facial paralysis and preparation method thereof.
Background technology
Facial paralysis, facial spasm is attacked outside ailment said due to cold or exposure, essential resistance of turbid phlegm, qi deficiency to blood stasis, train of thought are hollow, QI-blood circulation not smooth, train of thought
Lose to support and cause, be a kind of common disease by principal character of facial expression muscle group dyskinesia, the morbidity of this disease is anxious, recovers tired
Difficulty, brings unlimited pain and decocts to many patients.Clinically still lack corresponding medicine evident in efficacy and method.
The method that current facial paralysis is used mostly has:1. western medicine:Current doctor trained in Western medicine there is no to be controlled for the effective of this disease
Medicine is treated, for example:Subsided a swelling with glucocorticoid, anti-inflammatory, suppress immune response or using vasodilator and vitamin etc., but
It is that curative effect is undesirable and the state of an illness easily recurs it was verified that these Western medicine therapies are to cure the symptoms, not the disease.2. physiotherapy:For example with red
Outside line, massage, muscular movement exercise etc..3. acupuncture.Acupuncture is the quintessence of Chinese culture of China, also has preferable curative effect to facial paralysis, but use
It is more painful during acupuncture and moxibustion therapy, and it is careless slightly easily cause facial channels and collaterals be damaged, so as to cause illness protracted course of disease, make patient
It is painful lifelong.Although also there is the Chinese medicine of corresponding facial paralysis at present, prescription is complicated, medical expense is high.
The content of the invention
In order to solve the problems such as current facial paralysis treatment method can not be eradicated, therapeutic process is more painful and costly, this
The purpose of invention is to propose a kind of quick-acting water-honeyed pills of facial paralysis and preparation method thereof, and the quick-acting water-honeyed pills can be controlled effectively
Treat facial paralysis, facioplegia and deviation of the mouth with numbness and paralysis caused by the various causes of disease, and convenient to take, no pain, the various performances to facial paralysis
Symptom takes effect rapidly, it is adaptable to the patient of all age group.
A kind of quick-acting water-honeyed pills of facial paralysis, according to weight ratio, the preparing raw material of the water-honeyed pill is by by processing
15-20 parts of Radix Angelicae Sinensis, 20-25 parts of cassia twig, 20-25 parts of Ligusticum wallichiis, 25-30 parts of yncaria stems with hooks, 20-25 parts of centipedes, 15-20 parts of scorpios, 10-15
Part monkshood, 10-15 portions of rhizoma zingiberis, 20-25 parts of stiff silkworms, 10-15 portions of radix glycyrrhizaes, 15-20 portions of rhizoma alismatis, 10-20 portions of schizonepeta and 10-20 parts of Fu
Siberian cocklebur constitutes.
A kind of preparation method of the quick-acting water-honeyed pills of facial paralysis, comprises the following steps:
Step 1: taking Radix Angelicae Sinensis, cassia twig, Ligusticum wallichii, monkshood, radix glycyrrhizae, rhizoma alismatis, yncaria stem with hooks, schizonepeta and Poria cocos mixing to grind according to aforementioned proportion
Grinds, cross 150 mesh sieves, unsifted to repeat to grind, and reach 40% to the fine powder amount for crossing 150 mesh sieves, collect and pass through 150 mesh sieves
Fine powder I, it is standby;It will not cross in the coarse powder input multi-function extractor of 150 mesh sieves, add the decocting of 10 times of amounts of coarse powder gross weight
Boil 2 hours, filter to obtain decoction I, 1 hour, mistake are boiled in the decocting for then adding 5 times of amounts of remaining dregs of a decoction gross weight again into extractor
Decoction II is filtered to obtain, merges decoction I and decoction II is filtered, obtain filtrate I standby;
Step 2: stiff silkworm and wheat bran are compared into 10 according to weight:1 ratio is put into pot 180 DEG C of fryings 5 minutes, until stiff silkworm table
Taken out when being in coke black in golden yellow, wheat bran, wheat bran skin is weeded out while hot, stays stiff silkworm to spread out and cools in face;According to aforementioned proportion by Wu
Centipede, scorpio, stiff silkworm are put into hot reflux, add centipede, 90% ethanol of 10 times of amounts of scorpio and stiff silkworm gross weight and extract, heat
Refluxing extraction 45 minutes, obtains extract solution I, adds 90% ethanol of 10 times of amounts of remaining dregs of a decoction gross weight again into hot reflux,
Circumfluence distillation 45 minutes, obtains extract solution II, and extract solution I and extract solution II are mixed, and filtrate II is obtained after filtering, standby, because
Active ingredient in the medicines such as stiff silkworm is alcohol-soluble, therefore uses this extracting method;
Step 3: filtrate I and filtrate II are mixed, heat is concentrated into pasty state, is put into baking oven under conditions of 80 DEG C drying, cold
But, fine powder II is ground to form, fine powder II is mixed with fine powder I, honey is called in, the readily available water of water-honeyed pill, as facial paralysis is made
Honeyed bolus.
Described water-honeyed pill is taken after mixing it with water with ginger decoction.
The preparation method of described ginger decoction is:Take 3-5 pieces old ginger and 500mL drinking water to be put into the pot of cleaning, use slow fire
Infusion, fire is closed when liquid boiling in pot is evaporated to 300mL, ginger splices is discarded, remaining liq is ginger decoction.
Described old ginger removes impurity when processing, and slightly steeps, and cleans, runs through, cut sheet or block, dries.It is medicinal to be dissipated for middle benefit gas
It is cold, Back to Yang Tongmai, Wenfei of drink.Clinically it is usually used in coldness and pain in the epigastrium, vomiting and diarrhea, cold weak pulse of limb, cold drink such as is breathed with cough the disease.
Beneficial effects of the present invention:
Quick-acting water-honeyed pills of a kind of facial paralysis of the present invention and preparation method thereof, for facial palsy caused by a variety of causes
Shape takes effect rapidly, and wherein rhizoma alismatis has clearing damp and promoting diuresis, and the effect expelled the heat-evil, stiff silkworm has Inflammation Zhijing, wind-expelling pain-stopping, reducing phlegm and resolving masses
Effect, centipede has ceases wind antispastic, removes obstruction in channels to relieve pain, the effect of dispersing pathogen accumulation, and scorpio has only convulsion, wind-dispelling, dredging collateral, removing toxic substances
Effect, Ligusticum wallichii has the effect of blood-activating and qi-promoting, wind-expelling pain-stopping, and Radix Angelicae Sinensis has the effect enriching blood, invigorate blood circulation, stimulating the menstrual flow, and cassia twig has hair
The effect of sweat expelling pathogenic factors from muscles and skin, warming meridian, face deadlock can be alleviated for two to three days by taking, and being taken according to the state of an illness can recover after one week, be consolidated
Admittedly taking can fully recover after two weeks, effect is notable and rapid, it is adaptable to the patient of all age group, and Chinese medicinal formulae is made into water
Honeyed bolus, conveniently takes, and the pain of patient's medication is alleviated, while being easy to mass production to promote.
Embodiment
With reference to specific examples below, the present invention is described in further detail, and protection scope of the present invention is not limited to
In following examples.Implement process, condition, reagent, experimental method of the present invention etc., in addition to the following content specially referred to,
It is the universal knowledege and common knowledge of this area, content is not particularly limited in the present invention.
A kind of quick-acting water-honeyed pills of facial paralysis, according to weight ratio, the preparing raw material of the water-honeyed pill is by by processing
15-20 parts of Radix Angelicae Sinensis, 20-25 parts of cassia twig, 20-25 parts of Ligusticum wallichiis, 25-30 parts of yncaria stems with hooks, 20-25 parts of centipedes, 15-20 parts of scorpios, 10-15
Part monkshood, 10-15 portions of rhizoma zingiberis, 20-25 parts of stiff silkworms, 10-15 portions of radix glycyrrhizaes, 15-20 portions of rhizoma alismatis, 10-20 portions of schizonepeta and 10-20 parts of Fu
Siberian cocklebur constitutes.
A kind of preparation method of the quick-acting water-honeyed pills of facial paralysis, comprises the following steps:
Step 1: taking Radix Angelicae Sinensis, cassia twig, Ligusticum wallichii, monkshood, radix glycyrrhizae, rhizoma alismatis, yncaria stem with hooks, schizonepeta and Poria cocos mixing to grind according to aforementioned proportion
Grinds, cross 150 mesh sieves, unsifted to repeat to grind, and reach 40% to the fine powder amount for crossing 150 mesh sieves, collect and pass through 150 mesh sieves
Fine powder I, it is standby;It will not cross in the coarse powder input multi-function extractor of 150 mesh sieves, add the decocting of 10 times of amounts of coarse powder gross weight
Boil 2 hours, filter to obtain decoction I, 1 hour, mistake are boiled in the decocting for then adding 5 times of amounts of remaining dregs of a decoction gross weight again into extractor
Decoction II is filtered to obtain, merges decoction I and decoction II is filtered, obtain filtrate I standby;
Step 2: stiff silkworm and wheat bran are compared into 10 according to weight:1 ratio is put into pot 180 DEG C of fryings 5 minutes, until stiff silkworm table
Taken out when being in coke black in golden yellow, wheat bran, wheat bran skin is weeded out while hot, stays stiff silkworm to spread out and cools in face;According to aforementioned proportion by Wu
Centipede, scorpio, stiff silkworm are put into hot reflux, add centipede, 90% ethanol of 10 times of amounts of scorpio and stiff silkworm gross weight and extract, heat
Refluxing extraction 45 minutes, obtains extract solution I, adds 90% ethanol of 10 times of amounts of remaining dregs of a decoction gross weight again into hot reflux,
Circumfluence distillation 45 minutes, obtains extract solution II, and extract solution I and extract solution II are mixed, and filtrate II is obtained after filtering, standby, because
Active ingredient in the medicines such as stiff silkworm is alcohol-soluble, therefore uses this extracting method;
Step 3: filtrate I and filtrate II are mixed, heat is concentrated into pasty state, is put into baking oven under conditions of 80 DEG C drying, cold
But, fine powder II is ground to form, fine powder II is mixed with fine powder I, honey is called in, the readily available water of water-honeyed pill, as facial paralysis is made
Honeyed bolus.
Described water-honeyed pill is taken after mixing it with water with ginger decoction.
The preparation method of described ginger decoction is:Take 3-5 pieces old ginger and 500mL drinking water to be put into the pot of cleaning, use slow fire
Infusion, fire is closed when liquid boiling in pot is evaporated to 300mL, ginger splices is discarded, remaining liq is ginger decoction.
Described old ginger removes impurity when processing, and slightly steeps, and cleans, runs through, cut sheet or block, dries.It is medicinal to be dissipated for middle benefit gas
It is cold, Back to Yang Tongmai, Wenfei of drink.Clinically it is usually used in coldness and pain in the epigastrium, vomiting and diarrhea, cold weak pulse of limb, cold drink such as is breathed with cough the disease.
Described stiff silkworm, it is salty, pungent, flat.Return liver, lung, stomach.Major function Inflammation Zhijing, wind-expelling pain-stopping, reducing phlegm and resolving masses.
Phlegm is pressed from both sides for liver wind, twitch, acute infantile convulsion is caught cold, middle air port crucible, headache due to pathogenic wind-heat, hot eyes pharyngalgia, rubella itch, hair
Nourish mumps.
Described scorpio, it is pungent, flat, poisonous.Return liver warp.Major function ceases wind antispastic, dispersing pathogen accumulation is removed obstruction in channels to relieve pain.For
Child convulsion, tic spasm, middle air port is askew, hemiplegia, lockjaw, rheumatoid arthritis stubborn, migraine and general headache, sore, scrofula.
Described rhizoma alismatis, it is sweet, light, tremble with fear.Return kidney, bladder warp.Major function clearing damp and promoting diuresis, expels the heat-evil, and changes turbid lipid-loweringing.For small
Just it is unfavorable, oedema turgor, oliguria of having loose bowels, phlegmatic vertigo, puckery pain of heat gonorrhea, hyperlipidemia.
Described centipede, pungent, temperature;It is poisonous.Return liver warp.Major function ceases wind antispastic, removes obstruction in channels to relieve pain, dispersing pathogen accumulation.For
Liver wind agitation, spasm is twitched, child convulsion, middle air port crucible, hemiplegia, lockjaw, rheumatoid arthritis stubborn, migraine and general headache, sore, scrofula
Scrofula, snake bite and insect sting, pregnant woman's disabling.
Described Ligusticum wallichii, pungent, temperature.Return liver, courage, pericardium channel.Major function blood-activating and qi-promoting, wind-expelling pain-stopping.For the obstruction of qi in the chest heart
Bitterly, chest side of body shouting pain, tumbling and swelling, irregular menstruation, closed dysmenorrhea , Disorder lump in the abdomen is suffered from abdominal pain, headache, arthralgia pain due to rheumatism is the good of regulating qi to disperse stagnation
Medicine.
Described Radix Angelicae Sinensis, sweet, acrid, warm.Return liver, the heart, the spleen channel.Major function replenishing and activating blood, menstruction regulating and pain relieving relaxes bowel.
For blood deficiency chlorosis, dizziness palpitaition, irregular menstruation, closed dysmenorrhea, asthenia cold abdominalgia, arthralgia pain due to rheumatism, injury from falling down, ulcer sores,
Dry constipation of intestines.Prepared RADIX ANGELICAE SINENSIS with yellow rice wine invigorate blood circulation, for closed dysmenorrhea, arthralgia pain due to rheumatism, injury from falling down.
Embodiment 1
A kind of quick-acting water-honeyed pills of facial paralysis, according to weight ratio, the preparing raw material of the water-honeyed pill is by 15 parts by processing
Radix Angelicae Sinensis, 20 parts of cassia twig, 20 parts of Ligusticum wallichiis, 25 parts of yncaria stems with hooks, 20 parts of centipedes, 15 portions of scorpios, 10 parts of monkshoods, 10 portions of rhizoma zingiberis, 20 parts of stiff silkworms,
10 portions of radix glycyrrhizaes, 15 portions of rhizoma alismatis, 10 portions of schizonepeta and 10 parts of Poria cocos compositions.
A kind of preparation method of the quick-acting water-honeyed pills of facial paralysis, comprises the following steps:
Step 1: taking Radix Angelicae Sinensis, cassia twig, Ligusticum wallichii, monkshood, radix glycyrrhizae, rhizoma alismatis, yncaria stem with hooks, schizonepeta and Poria cocos mixing to grind according to aforementioned proportion
Grinds, cross 150 mesh sieves, unsifted to repeat to grind, and reach 40% to the fine powder amount for crossing 150 mesh sieves, collect and pass through 150 mesh sieves
Fine powder I, it is standby;It will not cross in the coarse powder input multi-function extractor of 150 mesh sieves, add the decocting of 10 times of amounts of coarse powder gross weight
Boil 2 hours, filter to obtain decoction I, 1 hour, mistake are boiled in the decocting for then adding 5 times of amounts of remaining dregs of a decoction gross weight again into extractor
Filter to obtain decoction II, merge decoction I and decoction II is filtered, obtain that filtrate I is standby, because the active ingredient in the medicine such as stiff silkworm is that alcohol is molten
Property, therefore use this extracting method;
Step 2: stiff silkworm and wheat bran are compared into 10 according to weight:1 ratio is put into pot 180 DEG C of fryings 5 minutes, until stiff silkworm table
Taken out when being in coke black in golden yellow, wheat bran, wheat bran skin is weeded out while hot, stays stiff silkworm to spread out and cools in face;According to aforementioned proportion by Wu
Centipede, scorpio, stiff silkworm are put into hot reflux, add centipede, 90% ethanol of 10 times of amounts of scorpio and stiff silkworm gross weight and extract, heat
Refluxing extraction 45 minutes, obtains extract solution I, adds 90% ethanol of 10 times of amounts of remaining dregs of a decoction gross weight again into hot reflux,
Circumfluence distillation 45 minutes, obtains extract solution II, and extract solution I and extract solution II are mixed, and filtrate II is obtained after filtering, standby;
Step 3: filtrate I and filtrate II are mixed, heat is concentrated into pasty state, is put into baking oven under conditions of 80 DEG C drying, cold
But, fine powder II is ground to form, fine powder II is mixed with fine powder I, honey is called in, the readily available water of water-honeyed pill, as facial paralysis is made
Honeyed bolus.
Embodiment 2
A kind of quick-acting water-honeyed pills of facial paralysis, according to weight ratio, the preparing raw material of the water-honeyed pill is by 16 parts by processing
Radix Angelicae Sinensis, 21 parts of cassia twig, 21 parts of Ligusticum wallichiis, 26 parts of yncaria stems with hooks, 21 parts of centipedes, 16 portions of scorpios, 12 parts of monkshoods, 12 portions of rhizoma zingiberis, 21 parts of stiff silkworms,
12 portions of radix glycyrrhizaes, 16 portions of rhizoma alismatis, 13 portions of schizonepeta and 13 parts of Poria cocos compositions.
A kind of preparation method of the quick-acting water-honeyed pills of facial paralysis, comprises the following steps:
Step 1: taking Radix Angelicae Sinensis, cassia twig, Ligusticum wallichii, monkshood, radix glycyrrhizae, rhizoma alismatis, yncaria stem with hooks, schizonepeta and Poria cocos mixing to grind according to aforementioned proportion
Grinds, cross 150 mesh sieves, unsifted to repeat to grind, and reach 40% to the fine powder amount for crossing 150 mesh sieves, collect and pass through 150 mesh sieves
Fine powder I, it is standby;It will not cross in the coarse powder input multi-function extractor of 150 mesh sieves, add the decocting of 10 times of amounts of coarse powder gross weight
Boil 2 hours, filter to obtain decoction I, 1 hour, mistake are boiled in the decocting for then adding 5 times of amounts of remaining dregs of a decoction gross weight again into extractor
Decoction II is filtered to obtain, merges decoction I and decoction II is filtered, obtain filtrate I standby;
Step 2: stiff silkworm and wheat bran are compared into 10 according to weight:1 ratio is put into pot 180 DEG C of fryings 5 minutes, until stiff silkworm table
Taken out when being in coke black in golden yellow, wheat bran, wheat bran skin is weeded out while hot, stays stiff silkworm to spread out and cools in face;According to aforementioned proportion by Wu
Centipede, scorpio, stiff silkworm are put into hot reflux, add centipede, 90% ethanol of 10 times of amounts of scorpio and stiff silkworm gross weight and extract, heat
Refluxing extraction 45 minutes, obtains extract solution I, adds 90% ethanol of 10 times of amounts of remaining dregs of a decoction gross weight again into hot reflux,
Circumfluence distillation 45 minutes, obtains extract solution II, and extract solution I and extract solution II are mixed, and filtrate II is obtained after filtering, standby, because
Active ingredient in the medicines such as stiff silkworm is alcohol-soluble, therefore uses this extracting method;
Step 3: filtrate I and filtrate II are mixed, heat is concentrated into pasty state, is put into baking oven under conditions of 80 DEG C drying, cold
But, fine powder II is ground to form, fine powder II is mixed with fine powder I, honey is called in, the readily available water of water-honeyed pill, as facial paralysis is made
Honeyed bolus.
Embodiment 3
A kind of quick-acting water-honeyed pills of facial paralysis, according to weight ratio, the preparing raw material of the water-honeyed pill is by 17 parts by processing
Radix Angelicae Sinensis, 23 parts of cassia twig, 23 parts of Ligusticum wallichiis, 27 parts of yncaria stems with hooks, 23 parts of centipedes, 17 portions of scorpios, 13 parts of monkshoods, 13 portions of rhizoma zingiberis, 23 parts of stiff silkworms,
13 portions of radix glycyrrhizaes, 17 portions of rhizoma alismatis, 15 portions of schizonepeta and 15 parts of Poria cocos compositions.
A kind of preparation method of the quick-acting water-honeyed pills of facial paralysis, comprises the following steps:
Step 1: taking Radix Angelicae Sinensis, cassia twig, Ligusticum wallichii, monkshood, radix glycyrrhizae, rhizoma alismatis, yncaria stem with hooks, schizonepeta and Poria cocos mixing to grind according to aforementioned proportion
Grinds, cross 150 mesh sieves, unsifted to repeat to grind, and reach 40% to the fine powder amount for crossing 150 mesh sieves, collect and pass through 150 mesh sieves
Fine powder I, it is standby;It will not cross in the coarse powder input multi-function extractor of 150 mesh sieves, add the decocting of 10 times of amounts of coarse powder gross weight
Boil 2 hours, filter to obtain decoction I, 1 hour, mistake are boiled in the decocting for then adding 5 times of amounts of remaining dregs of a decoction gross weight again into extractor
Decoction II is filtered to obtain, merges decoction I and decoction II is filtered, obtain filtrate I standby;
Step 2: stiff silkworm and wheat bran are compared into 10 according to weight:1 ratio is put into pot 180 DEG C of fryings 5 minutes, until stiff silkworm table
Taken out when being in coke black in golden yellow, wheat bran, wheat bran skin is weeded out while hot, stays stiff silkworm to spread out and cools in face;According to aforementioned proportion by Wu
Centipede, scorpio, stiff silkworm are put into hot reflux, add centipede, 90% ethanol of 10 times of amounts of scorpio and stiff silkworm gross weight and extract, heat
Refluxing extraction 45 minutes, obtains extract solution I, adds 90% ethanol of 10 times of amounts of remaining dregs of a decoction gross weight again into hot reflux,
Circumfluence distillation 45 minutes, obtains extract solution II, and extract solution I and extract solution II are mixed, and filtrate II is obtained after filtering, standby, because
Active ingredient in the medicines such as stiff silkworm is alcohol-soluble, therefore uses this extracting method;
Step 3: filtrate I and filtrate II are mixed, heat is concentrated into pasty state, is put into baking oven under conditions of 80 DEG C drying, cold
But, fine powder II is ground to form, fine powder II is mixed with fine powder I, honey is called in, the readily available water of water-honeyed pill, as facial paralysis is made
Honeyed bolus.
Embodiment 4
A kind of quick-acting water-honeyed pills of facial paralysis, according to weight ratio, the preparing raw material of the water-honeyed pill is by 19 parts by processing
Radix Angelicae Sinensis, 24 parts of cassia twig, 24 parts of Ligusticum wallichiis, 28 parts of yncaria stems with hooks, 24 parts of centipedes, 19 portions of scorpios, 14 parts of monkshoods, 14 portions of rhizoma zingiberis, 24 parts of stiff silkworms,
14 portions of radix glycyrrhizaes, 19 portions of rhizoma alismatis, 18 portions of schizonepeta and 18 parts of Poria cocos compositions.
A kind of preparation method of the quick-acting water-honeyed pills of facial paralysis, comprises the following steps:
Step 1: taking Radix Angelicae Sinensis, cassia twig, Ligusticum wallichii, monkshood, radix glycyrrhizae, rhizoma alismatis, yncaria stem with hooks, schizonepeta and Poria cocos mixing to grind according to aforementioned proportion
Grinds, cross 150 mesh sieves, unsifted to repeat to grind, and reach 40% to the fine powder amount for crossing 150 mesh sieves, collect and pass through 150 mesh sieves
Fine powder I, it is standby;It will not cross in the coarse powder input multi-function extractor of 150 mesh sieves, add the decocting of 10 times of amounts of coarse powder gross weight
Boil 2 hours, filter to obtain decoction I, 1 hour, mistake are boiled in the decocting for then adding 5 times of amounts of remaining dregs of a decoction gross weight again into extractor
Decoction II is filtered to obtain, merges decoction I and decoction II is filtered, obtain filtrate I standby;
Step 2: stiff silkworm and wheat bran are compared into 10 according to weight:1 ratio is put into pot 180 DEG C of fryings 5 minutes, until stiff silkworm table
Taken out when being in coke black in golden yellow, wheat bran, wheat bran skin is weeded out while hot, stays stiff silkworm to spread out and cools in face;According to aforementioned proportion by Wu
Centipede, scorpio, stiff silkworm are put into hot reflux, add centipede, 90% ethanol of 10 times of amounts of scorpio and stiff silkworm gross weight and extract, heat
Refluxing extraction 45 minutes, obtains extract solution I, adds 90% ethanol of 10 times of amounts of remaining dregs of a decoction gross weight again into hot reflux,
Circumfluence distillation 45 minutes, obtains extract solution II, and extract solution I and extract solution II are mixed, and filtrate II is obtained after filtering, standby, because
Active ingredient in the medicines such as stiff silkworm is alcohol-soluble, therefore uses this extracting method;
Step 3: filtrate I and filtrate II are mixed, heat is concentrated into pasty state, is put into baking oven under conditions of 80 DEG C drying, cold
But, fine powder II is ground to form, fine powder II is mixed with fine powder I, honey is called in, the readily available water of water-honeyed pill, as facial paralysis is made
Honeyed bolus.
Embodiment 5
A kind of quick-acting water-honeyed pills of facial paralysis, according to weight ratio, the preparing raw material of the water-honeyed pill is by 20 parts by processing
Radix Angelicae Sinensis, 25 parts of cassia twig, 25 parts of Ligusticum wallichiis, 30 parts of yncaria stems with hooks, 25 parts of centipedes, 20 portions of scorpios, 15 parts of monkshoods, 15 portions of rhizoma zingiberis, 25 parts of stiff silkworms,
15 portions of radix glycyrrhizaes, 20 portions of rhizoma alismatis, 20 portions of schizonepeta and 20 parts of Poria cocos compositions.
A kind of preparation method of the quick-acting water-honeyed pills of facial paralysis, comprises the following steps:
Step 1: taking Radix Angelicae Sinensis, cassia twig, Ligusticum wallichii, monkshood, radix glycyrrhizae, rhizoma alismatis, yncaria stem with hooks, schizonepeta and Poria cocos mixing to grind according to aforementioned proportion
Grinds, cross 150 mesh sieves, unsifted to repeat to grind, and reach 40% to the fine powder amount for crossing 150 mesh sieves, collect and pass through 150 mesh sieves
Fine powder I, it is standby;It will not cross in the coarse powder input multi-function extractor of 150 mesh sieves, add the decocting of 10 times of amounts of coarse powder gross weight
Boil 2 hours, filter to obtain decoction I, 1 hour, mistake are boiled in the decocting for then adding 5 times of amounts of remaining dregs of a decoction gross weight again into extractor
Decoction II is filtered to obtain, merges decoction I and decoction II is filtered, obtain filtrate I standby;
Step 2: stiff silkworm and wheat bran are compared into 10 according to weight:1 ratio is put into pot 180 DEG C of fryings 5 minutes, until stiff silkworm table
Taken out when being in coke black in golden yellow, wheat bran, wheat bran skin is weeded out while hot, stays stiff silkworm to spread out and cools in face;According to aforementioned proportion by Wu
Centipede, scorpio, stiff silkworm are put into hot reflux, add centipede, 90% ethanol of 10 times of amounts of scorpio and stiff silkworm gross weight and extract, heat
Refluxing extraction 45 minutes, obtains extract solution I, adds 90% ethanol of 10 times of amounts of remaining dregs of a decoction gross weight again into hot reflux,
Circumfluence distillation 45 minutes, obtains extract solution II, and extract solution I and extract solution II are mixed, and filtrate II is obtained after filtering, standby, because
Active ingredient in the medicines such as stiff silkworm is alcohol-soluble, therefore uses this extracting method;
Step 3: filtrate I and filtrate II are mixed, heat is concentrated into pasty state, is put into baking oven under conditions of 80 DEG C drying, cold
But, fine powder II is ground to form, fine powder II is mixed with fine powder I, honey is called in, the readily available water of water-honeyed pill, as facial paralysis is made
Honeyed bolus.
Medication taboo:
During quick-acting water-honeyed pills of the present invention are taken, fasting is pungent, peppery, irritable food, quits smoking, wine, the gestational period and lactation
Women's disabling of phase, hypertension, heart patient use with caution, and the patient for having cerebral infarction medical history uses with caution.
Clinical case:
Liu so-and-so, female, 56 years old, apoplexy caused facial paralysis at 55 years old, and symptom is that face is stiff, and deviation of the mouth with numbness and paralysis is shed tears, stagnant food, leak, it is impossible to
The drum cheek.Take 2-3 days of the present invention, 3 times a day, each 15-20g, symptom is relieved, stagnant food, leak symptom substantially mitigates, again
Hold on recovery from illness after a week after taking, does not recur so far.
Mr. Wang, female 48 years old, suffers from facioplegia, symptom is deviation of the mouth with numbness and paralysis, and ptosis of labial angle is shed tears, stagnant food at 46 years old,
Leak, it is impossible to the drum cheek.Take 3-4 days of the present invention, 3 times a day, each 15-20g, symptom is relieved, continue to take after one week
Deviation of the mouth with numbness and paralysis disappears, then takes one week of the invention and consolidate curative effect, fully recovers, does not recur again so far.
Week so-and-so, man, 23 years old, with facioplegia, symptom was deviation of the mouth with numbness and paralysis, is shed tears, stagnant food, leak, ptosis of labial angle,
The cheek can not be roused.Take 2-3 days of the present invention, 3 times a day, each 10-15g, face deadlock is relieved, continue base after taking 3-5 days
This recovery, then recovery from illness after one week of the invention is taken, do not recur so far.
Zhang, man, 36 years old, apoplexy caused facial paralysis at 35 years old, and symptom is that face is stiff, and deviation of the mouth with numbness and paralysis is shed tears, stagnant food, leak,
The cheek can not be roused.Take 1-3 days of the present invention, 3 times a day, each 15-25g, face deadlock is relieved, continue base after taking 3-5 days
This recovery, then recovery from illness after one week of the invention is taken, do not recur so far.
Gong so-and-so, female, 25 years old, with facioplegia, cardinal symptom was deviation of the mouth with numbness and paralysis, is shed tears, stagnant food, leak, bicker
It is sagging, it is impossible to the drum cheek.Take 3-5 days of the present invention, 3 times a day, each 10-15g, face deadlock is relieved, continue to take 5-7 days it
It is basic afterwards to recover, then recovery from illness after two weeks of the invention is taken, do not recur so far.
Claims (2)
1. a kind of quick-acting water-honeyed pills of facial paralysis, it is characterised in that:According to weight ratio, the preparing raw material of the water-honeyed pill is by passing through
Cross the 15-20 part Radix Angelicae Sinensis processed, 20-25 parts of cassia twig, 20-25 parts of Ligusticum wallichiis, 25-30 parts of yncaria stems with hooks, 20-25 parts of centipedes, 15-20 parts entirely
Scorpion, 10-15 part monkshood, 10-15 portions of rhizoma zingiberis, 20-25 parts of stiff silkworms, 10-15 portions of radix glycyrrhizaes, 15-20 portions of rhizoma alismatis, 10-20 portions of schizonepeta and
10-20 parts of Poria cocos compositions.
2. a kind of preparation method of the quick-acting water-honeyed pills of facial paralysis as claimed in claim 1, it is characterised in that:Including following
Step:
Step 1: taking Radix Angelicae Sinensis, cassia twig, Ligusticum wallichii, monkshood, radix glycyrrhizae, rhizoma alismatis, yncaria stem with hooks, schizonepeta and Poria cocos mixing to grind according to aforementioned proportion
Grinds, cross 150 mesh sieves, unsifted to repeat to grind, and reach 40% to the fine powder amount for crossing 150 mesh sieves, collect and pass through 150 mesh sieves
Fine powder I, it is standby;It will not cross in the coarse powder input multi-function extractor of 150 mesh sieves, add the decocting of 10 times of amounts of coarse powder gross weight
Boil 2 hours, filter to obtain decoction I, 1 hour, mistake are boiled in the decocting for then adding 5 times of amounts of remaining dregs of a decoction gross weight again into extractor
Decoction II is filtered to obtain, it is standby that merging decoction I and decoction II obtain filtrate I;
Step 2: stiff silkworm and wheat bran are compared into 10 according to weight:1 ratio is put into pot 180 DEG C of fryings 5 minutes, until stiff silkworm table
Taken out when being in coke black in golden yellow, wheat bran, wheat bran skin is weeded out while hot, stays stiff silkworm to spread out and cools in face;According to aforementioned proportion by Wu
Centipede, scorpio, stiff silkworm are put into hot reflux, add centipede, the ethanol of 10 times of amounts of scorpio and stiff silkworm gross weight and extract, heat backflow is carried
Take 45 minutes, obtain extract solution I, add the ethanol of 10 times of amounts of remaining dregs of a decoction gross weight again into hot reflux, heat backflow is carried
Take 45 minutes, obtain extract solution II, extract solution I and extract solution II are mixed, filtrate II is obtained after filtering, it is standby;
Step 3: filtrate I and filtrate II are mixed, heat is concentrated into pasty state, is put into baking oven under conditions of 80 DEG C drying, cold
But, fine powder II is ground to form, fine powder II is mixed with fine powder I, honey is called in, the readily available water of water-honeyed pill, as facial paralysis is made
Honeyed bolus.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710516732.XA CN107233551A (en) | 2017-06-29 | 2017-06-29 | A kind of quick-acting water-honeyed pills of facial paralysis and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710516732.XA CN107233551A (en) | 2017-06-29 | 2017-06-29 | A kind of quick-acting water-honeyed pills of facial paralysis and preparation method thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CN107233551A true CN107233551A (en) | 2017-10-10 |
Family
ID=59990056
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710516732.XA Pending CN107233551A (en) | 2017-06-29 | 2017-06-29 | A kind of quick-acting water-honeyed pills of facial paralysis and preparation method thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN107233551A (en) |
-
2017
- 2017-06-29 CN CN201710516732.XA patent/CN107233551A/en active Pending
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN104958484A (en) | traditional Chinese medicine unguent for promoting blood circulation to remove meridian obstruction and preparing method of traditional Chinese medicine unguent | |
CN106421663A (en) | Medicine composition for treating rheumatoid bone disease and preparation method thereof | |
CN105106525A (en) | Zhuifeng wine used for treating rheumatic and rheumatoid arthritis arthralgia and preparation method thereof | |
CN104758743A (en) | Traditional Chinese medicine foot fumigating powder for treating rheumatism as well as preparation method and using method thereof | |
CN107233550A (en) | A kind of Chinese medicine composition of facial paralysis and preparation method thereof | |
CN106177163A (en) | A kind of for decoction medicine treating pruritus and preparation method thereof | |
CN105497351A (en) | Traditional Chinese medicine composition for treating facioplegia and preparation method thereof | |
CN107233551A (en) | A kind of quick-acting water-honeyed pills of facial paralysis and preparation method thereof | |
CN104707098A (en) | Internal drug for treating chronic blepharoconjunctivitis and preparation method of internal drug | |
CN103784879A (en) | Compound traditional Chinese medicinal preparation for treating ischemic cerebrovascular diseases | |
CN104083719A (en) | Traditional Chinese medicine for treating hyperplasia of mammary glands and preparation method of traditional Chinese medicine | |
CN101912483B (en) | Traditional Chinese medicine embrocation of children infantile eczema | |
CN101912488A (en) | Chinese medicinal herb for treating hypomenorrhea | |
CN105641293A (en) | Traditional Chinese medicine composition treating pain in lateral lower abdomen and preparing method thereof | |
CN105663785A (en) | Traditional Chinese medicine composition for treating migraine and preparation method thereof | |
CN105535563A (en) | Traditional Chinese medicine composition for treating facial neuritis and preparing method thereof | |
CN104127557A (en) | Traditional Chinese medicine for treating liver cirrhosis | |
CN104922454A (en) | Orally-taken medicine for treating soft tissue contusion and preparation method thereof | |
CN104857349A (en) | Pure traditional Chinese medicine preparation for treating stroke and preparation method of pure traditional Chinese medicine preparation | |
CN104042727A (en) | Drugs for oral administration for treating shallow and deep part muscle abscess and preparation method thereof | |
CN104288377A (en) | Medicine composition for treating cerebral thrombosis | |
CN103830573A (en) | Foot bath Chinese medicine for treating phlegmatic hygrosis physique and preparation method thereof | |
CN101837115B (en) | Steamed and applied traditional Chinese medicine for promoting recovery after restoration of prolapse of lumbar intervertebral disc | |
CN113288948A (en) | Medicine for relieving external humeral epicondylitis | |
CN105770495A (en) | Traditional Chinese medicine for increasing bone density and dispelling joint pain and preparing method thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20171010 |