CN107233429A - A kind of external application Chinese herbal medicine and preparation method for treating hepatopathy - Google Patents
A kind of external application Chinese herbal medicine and preparation method for treating hepatopathy Download PDFInfo
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- CN107233429A CN107233429A CN201710556297.3A CN201710556297A CN107233429A CN 107233429 A CN107233429 A CN 107233429A CN 201710556297 A CN201710556297 A CN 201710556297A CN 107233429 A CN107233429 A CN 107233429A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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Abstract
The invention belongs to technical field of traditional Chinese medicines, a kind of external application Chinese herbal medicine and preparation method for treating hepatopathy is specifically disclosed, the Chinese herbal medicine is made up of the component of following parts by weight：20 25 parts of Herba portulacae, 35 40 parts of smallflower galinsoga herb, 25 35 parts of Sorrel.These three medicines are used in conjunction first for Chinese herbal medicine of the present invention, to reach enhancing drug effect, expand therapeutic domain, and few side effects.Clinical effectiveness shows, reaches the virus for excluding liver's hepatitis at wrist by Chinese herbal medicine external application, the face meeting gain color that hepatopath face Huang is become thin, the patient of apocleisis can be away from apocleisis, physical function can slowly recover after this used medicine half a year, and substantially, suitable large-scale promotion is used drug effect.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of external application Chinese herbal medicine and preparation method for treating hepatopathy.
Background technology
Liver cancer is China's malignant tumour occurred frequently, according to statistics, and 130,000 people are there are about every year and die from liver cancer, accounts for whole world liver cancer year
The 43.7% of death toll.After hepatopathy, controlled except actively the cause of disease, anti-inflammatory liver protection, anti-fibrosis, anti symptom treatment etc. is removed
Treat outer, good diet, daily life custom are formed in daily life, it is equally also particularly important.Treatment clinically is typically regarded at present
Operation, radiotherapy, chemotherapy are three big pillars, drug therapy are then equipped with, to improve patient symptom.
But, Chinese herbal medicine in the market is main based on for oral administration, mainly there is a pill Chinese patent drug, the finished product of electuary etc
Medicine, this medicine preparation process is complicated, and cost is high, and patient takes can produce bitterness sense.Medicine for external application is absorbed the drug by skin
Active ingredient, it is to avoid patient takes the bitterness sense of generation, it is therefore necessary to develop that a kind of preparation method is simple, cost is low and energy
The medicine for external application of enough effectively treatment hepatopathys.
The content of the invention
To solve the above problems, a kind of external application Chinese herbal medicine and preparation method for treating hepatopathy that the present invention is provided, is solved
Existing hepatopathy medicine for oral administration preparation process is complicated, and cost is high, and patient takes the problem of producing bitterness sense.
First purpose of the present invention is to provide a kind of external application Chinese herbal medicine for treating hepatopathy, by the component of following parts by weight
It is made：20-25 parts of Herba portulacae, 35-40 parts of smallflower galinsoga herb, 25-35 parts of Sorrel.
It is preferred that, the external application Chinese herbal medicine of above-mentioned treatment hepatopathy is made up of the component of following parts by weight：25 parts of Herba portulacae,
40 parts of smallflower galinsoga herb, 35 parts of Sorrel.
It is preferred that, the external application Chinese herbal medicine of above-mentioned treatment hepatopathy, the purslane uses the stem and leaf of fresh purslane,
The smallflower galinsoga herb uses the stem and leaf of fresh smallflower galinsoga herb, and the Sorrel uses the leaf of fresh Sorrel.
Second object of the present invention is to provide a kind of preparation method for the external application Chinese herbal medicine for treating hepatopathy, including following step
Suddenly：
Step 1, each component is weighed by following parts by weight：20-25 parts of Herba portulacae, 35-40 parts of smallflower galinsoga herb, Sorrel 25-
35 parts；
Step 2, the above-mentioned each component weighed is cleaned after drying, crushes, mixes respectively, mashed into paste shape is controlled
Treat the external application Chinese herbal medicine of hepatopathy.
Compared with prior art, the external application Chinese herbal medicine and preparation method for the treatment of hepatopathy of the invention, with following beneficial effect
Really：
1st, present hepatitis common medicine is all based on for oral administration, to make pharmaceutical procedures complexity, and cost is high, and patient takes and can produced
Raw bitterness sense.Not only mutually mended each other to cooperate between raw medicinal material effect selected by the present invention, manufacturing process is simple, cost is low
It is honest and clean, belong to ecosystem herbal medicine.
Although the 2, effect of the smallflower galinsoga herb with treatment acute icteric hepatitis, is had experiment to understand, is only made with smallflower galinsoga herb
For medicine, unsatisfactory curative effect.Purslane and Sorrel not yet find that it has effects that to treat hepatopathy at present.Chinese herbal medicine of the present invention is first
It is secondary that these three medicines are used in conjunction, by the compatibility effect between each drug component, to reach enhancing drug effect, expand therapeutic domain,
And few side effects.Clinical effectiveness shows, reaches the virus for excluding liver's hepatitis, hepatopath at wrist by Chinese herbal medicine external application
The face meeting gain color that face Huang is become thin, the patient of apocleisis can be away from apocleisis, and physical function can slowly recover after this used medicine half a year, give
Hepatitis is brought glad tidings, and substantially, suitable large-scale promotion is used drug effect.
Embodiment
With reference to specific embodiment, the present invention is described in detail, but should not be construed as the limitation of the present invention.Below
The experimental method of unreceipted actual conditions in embodiment, is carried out according to the conventional method and condition of this area.
The present invention provides a kind of external application Chinese herbal medicine for treating hepatopathy, is made up of the component of following parts by weight：Herba portulacae 20-
25 parts, 35-40 parts of smallflower galinsoga herb, 25-35 parts of Sorrel.
Said components have following effect and effect respectively：
Purslane：According to《National Chinese herbal medicine compilation》Record, purslane property tart flavour is trembled with fear.Major function：Clearing heat and promoting diuresis, cool blood
Removing toxic substances.For bacillary dysentery, acute gastroenteritis, acute appendicitis, mastitis, hemorrhoid hemorrhage, leukorrhea；External application is controlled furunculosis and swollen
Poison, eczema, herpes zoster.
Smallflower galinsoga herb：Scientific name root of bidentate achyranthes chrysanthemum, according to《Cover and plant medicine will》、《Dali provides will》Deng the record of document, smallflower galinsoga herb cures mainly flat
Peach body is scorching, sphagitis, hot eyes, acute icteric hepatitis, traumatism and bleeding.
Sorrel：Scientific name black nightshade, according to《Chinese book on Chinese herbal medicine》Record, Sorrel bitter；It is cold in nature, major function heat-clearing solution
Poison；Activating blood circulation and reducing swelling.Main furunculosis；Carbuncle swells；Erysipelas；Bruises and sprains；Chronic bronchitis；Nephritic dropsy.
It is preferred that, the present invention provides a kind of external application Chinese herbal medicine for treating hepatopathy, including following examples：
Embodiment 1
A kind of external application Chinese herbal medicine for treating hepatopathy, is made up of the component of following parts by weight：25 parts of Herba portulacae, smallflower galinsoga herb 40
Part, 35 parts of Sorrel, wherein the purslane uses the stem and leaf of fresh purslane, the smallflower galinsoga herb uses fresh
The stem and leaf of smallflower galinsoga herb, the Sorrel use the leaf of fresh Sorrel.Prepare according to the following steps：
Step 1, each component is weighed by following parts by weight：25 parts of Herba portulacae, 40 parts of smallflower galinsoga herb, 35 parts of Sorrel；Wherein
The purslane uses the stem and leaf of fresh purslane, and the smallflower galinsoga herb uses the stem and leaf of fresh smallflower galinsoga herb, institute
State the leaf that Sorrel uses fresh Sorrel；
Step 2, the above-mentioned each component weighed is cleaned after drying, crushes, mixes respectively, mashed into paste shape is controlled
Treat the external application Chinese herbal medicine of hepatopathy.
Embodiment 2
A kind of external application Chinese herbal medicine for treating hepatopathy, is made up of the component of following parts by weight：20 parts of Herba portulacae, smallflower galinsoga herb 35
Part, 25 parts of Sorrel, wherein the purslane uses the stem and leaf of fresh purslane, the smallflower galinsoga herb uses fresh
The stem and leaf of smallflower galinsoga herb, the Sorrel use the leaf of fresh Sorrel.Preparation method will be while example 1, will simply be formulated
It is changed to the formula of embodiment 2.
Embodiment 3
A kind of external application Chinese herbal medicine for treating hepatopathy, is made up of the component of following parts by weight：22 parts of Herba portulacae, smallflower galinsoga herb 38
Part, 30 parts of Sorrel, wherein the purslane uses the stem and leaf of fresh purslane, the smallflower galinsoga herb uses fresh
The stem and leaf of smallflower galinsoga herb, the Sorrel use the leaf of fresh Sorrel.Preparation method will be while example 1, will simply be formulated
It is changed to the formula of embodiment 3.
Embodiment 4
A kind of external application Chinese herbal medicine for treating hepatopathy, is made up of the component of following parts by weight：25 parts of Herba portulacae, smallflower galinsoga herb 38
Part, 32 parts of Sorrel, wherein the purslane uses the stem and leaf of fresh purslane, the smallflower galinsoga herb uses fresh
The stem and leaf of smallflower galinsoga herb, the Sorrel use the leaf of fresh Sorrel.Preparation method will be while example 1, will simply be formulated
It is changed to the formula of embodiment 4.
Embodiment 5
A kind of external application Chinese herbal medicine for treating hepatopathy, is made up of the component of following parts by weight：21 parts of Herba portulacae, smallflower galinsoga herb 36
Part, 33 parts of Sorrel, wherein the purslane uses the stem and leaf of fresh purslane, the smallflower galinsoga herb uses fresh
The stem and leaf of smallflower galinsoga herb, the Sorrel use the leaf of fresh Sorrel.Preparation method will be while example 1, will simply be formulated
It is changed to the formula of embodiment 5.
Embodiment 6
A kind of external application Chinese herbal medicine for treating hepatopathy, is made up of the component of following parts by weight：24 parts of Herba portulacae, smallflower galinsoga herb 39
Part, 26 parts of Sorrel, wherein the purslane uses the stem and leaf of fresh purslane, the smallflower galinsoga herb uses fresh
The stem and leaf of smallflower galinsoga herb, the Sorrel use the leaf of fresh Sorrel.Preparation method will be while example 1, will simply be formulated
It is changed to the formula of embodiment 6.
Some Clinic Cases are set forth below and by taking the formula of embodiment 1 as an example, illustrate the effect of medicine of the invention itself.
First, case selection standard
Primary Hepatic patient 50 is chosen as experimental group, 50 as a control group, and all cases are through pathological diagnosis
Or AFP measure, imageological examination etc. are clarified a diagnosis and be diagnosed as primary hepatopathy, wherein every group of male 25, women 25, age
35-70 Sui, liver cancer second phase patient 35, three phase of liver cancer patient 15 previously has Chronic Liver medical history 25, all cases are controlled
Treat history.
2nd, the index of hepatopathy curative effect
A kind of curative effect index of liver cancer is the indicator reaction of tumour, and the curative effect for being mainly used in the method for No operation excision is commented
Valency, such as using transcatheter hepatic arterial chemoembolization after, whether tumour reduces, cases of complete remission, is just called complete incidence graph, tumour
Maximum diameter reduces just makes part alleviate more than 30%, if the maximum diameter of tumour reduces is no more than 20% no more than 30%, increase,
Just cry stable, if increasing above 20%, or occur in that new focus, be just called progression of disease.
3rd, treatment method
The external application Chinese herbal medicine for being used to treat hepatopathy that 50 liver cancer cases of experimental group are provided using the embodiment of the present invention 1.
Application method is as follows：
Step (1), the external application Chinese herbal medicine of embodiment 1 is uniformly spread on the inside of wrist, and consumption is the single wrists of 10g/, with doctor
Wrapped up with gauze, skin starts to occur during bubble (about 24h) at wrist, untie gauze, clean wrist skin；Step (2), 7d
Bubble is punctured with disinfector afterwards, liquid toxin in bubble is bled off, and the skin of bubble is cut with disinfector, finally to wound
Carry out disinfection processing, is wrapped up with hospital gauze, and 12-24h changes a gauze, until growing after new skin, 3d, under then carrying out
Repetitive therapy, curative effect is observed after so repeating half a year.
The Chinese herbal medicine that 50 liver cancer cases of control group are used is after cleaning and drying by the stem and leaf of fresh smallflower galinsoga herb, to crush,
Then mashed into paste shape, uniformly will spread in wrist, the single wrists of 10g/ are wrapped up, skin starts at wrist with hospital gauze
Occur during bubble (about 36h), untiing gauze, clean wrist skin；Bubble is punctured with disinfector after 7d, liquid in bubble is bled off
Toxin, and the skin of bubble is cut with disinfector, finally carry out disinfection processing to wound, is wrapped up with hospital gauze, 12-24h
A gauze is changed, until growing after new skin, 3d, repetitive therapy next time is then carried out, so repeats to observe after half a year and treats
Effect.
4th, observation of curative effect
After treatment through half a year, experimental group has 43 conditions of patients to be clearly better, wherein complete incidence graph 20, and part is slow
Solution 23, unchanged 6, medicine effective percentage is 86%, and all patients have no side effect using after medicine.
After treatment through half a year, control group has 13 conditions of patients to be clearly better, wherein complete incidence graph 1, and part is slow
Solution 12, unchanged 37, medicine effective percentage is 26%, and all patients have no side effect using after medicine.
As a result show, the external application Chinese herbal medicine for treating hepatopathy that the embodiment of the present invention 1 is provided can effectively treat hepatopathy, face
Bed is evident in efficacy.The expression quantity of AFP liver cancer markers is remarkably decreased in serum, and the various symptoms of liver cancer are significantly improved.
5th, model case
1st, Lee, man, 40 years old, with the primary hepatopathy second phase, face Huang was become thin, lost the appetite, using the medicine of embodiment 1
Thing, and treated according to " three " above kind methods described, after half a year, complexion recovers ruddy, and appetite is recovered, AFP livers in serum
The expression quantity of carcinoma marker is remarkably decreased, and the various symptoms of liver cancer obtain complete incidence graph,.
2nd, certain is thanked, man, 52 years old, with the phase of primary hepatopathy three, face Huang was become thin, lost the appetite, using the medicine of embodiment 1
Thing, and treated according to " three " above kind methods described, after 9 months, complexion recovers ruddy, and appetite is recovered, AFP livers in serum
The expression quantity of carcinoma marker declines, and the various symptoms of liver cancer obtain part alleviation.
Although effect of the smallflower galinsoga herb with treatment acute icteric hepatitis, from above-mentioned experiment, only with smallflower galinsoga herb
It is used as medicine, unsatisfactory curative effect.Purslane and Sorrel not yet find that it has effects that to treat hepatopathy at present.The present invention first will
These three medicines are used in conjunction, by the compatibility effect between each drug component, to reach enhancing drug effect, expand therapeutic domain, and secondary
Effect is few；Furthermore it is simple, with low cost that the Chinese herbal medicine makees process, belongs to ecosystem herbal medicine, by Chinese herbal medicine external application at wrist
The virus for excluding liver's hepatitis is reached, substantially, suitable large-scale promotion is used drug effect.
It should be noted that in order to prevent from repeating, description of the invention preferred embodiment, due to embodiment 1-6's
As a result similar, the present invention only describes the effect of embodiment 1., but this area although preferred embodiments of the present invention have been described
Interior technical staff once knows basic creative concept, then other change and modification can be made to these embodiments.Institute
It is intended to be construed to include preferred embodiment with, appended claims and falls into having altered and changing for the scope of the invention.
Obviously, those skilled in the art can carry out the essence of various changes and modification without departing from the present invention to the present invention
God and scope.So, if these modifications and variations of the present invention belong to the scope of the claims in the present invention and its equivalent technologies
Within, then the present invention is also intended to comprising including these changes and modification.
Claims (4)
1. a kind of external application Chinese herbal medicine for treating hepatopathy, it is characterised in that be made up of the component of following parts by weight：Herba portulacae 20-
25 parts, 35-40 parts of smallflower galinsoga herb, 25-35 parts of Sorrel.
2. the external application Chinese herbal medicine for the treatment of hepatopathy according to claim 1, it is characterised in that by the component of following parts by weight
It is made：25 parts of Herba portulacae, 40 parts of smallflower galinsoga herb, 35 parts of Sorrel.
3. the external application Chinese herbal medicine for the treatment of hepatopathy according to claim 1, it is characterised in that the purslane uses newly
The stem and leaf of fresh purslane, the smallflower galinsoga herb use the stem and leaf of fresh smallflower galinsoga herb, and the Sorrel uses fresh
The leaf of Sorrel.
4. the preparation method of the external application Chinese herbal medicine for the treatment of hepatopathy according to claim 1, it is characterised in that including following step
Suddenly：
Step 1, each component is weighed by following parts by weight：20-25 parts of Herba portulacae, 35-40 parts of smallflower galinsoga herb, 25-35 parts of Sorrel；
Step 2, the above-mentioned each component weighed is cleaned after drying, crushes, mixes, mashed into paste shape respectively, that is, obtain medical treatment liver
The external application Chinese herbal medicine of disease.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710556297.3A CN107233429A (en) | 2017-07-10 | 2017-07-10 | A kind of external application Chinese herbal medicine and preparation method for treating hepatopathy |
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| CN201710556297.3A CN107233429A (en) | 2017-07-10 | 2017-07-10 | A kind of external application Chinese herbal medicine and preparation method for treating hepatopathy |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102302621A (en) * | 2011-08-19 | 2012-01-04 | 南充市创科生物科技有限责任公司 | Chinese herbal medicine for treating liver cancers |
| CN103340980A (en) * | 2013-07-15 | 2013-10-09 | 陈新强 | Medicine for treating liver ascites and preparation method thereof |
-
2017
- 2017-07-10 CN CN201710556297.3A patent/CN107233429A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102302621A (en) * | 2011-08-19 | 2012-01-04 | 南充市创科生物科技有限责任公司 | Chinese herbal medicine for treating liver cancers |
| CN103340980A (en) * | 2013-07-15 | 2013-10-09 | 陈新强 | Medicine for treating liver ascites and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 潘争红等: "牛膝菊中的萜类及甾醇类成分", 《云南大学学报（自然科学版）》 * |
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