CN107228785A - A kind of histogenic immunity groupization section humidification heater - Google Patents
A kind of histogenic immunity groupization section humidification heater Download PDFInfo
- Publication number
- CN107228785A CN107228785A CN201710473142.3A CN201710473142A CN107228785A CN 107228785 A CN107228785 A CN 107228785A CN 201710473142 A CN201710473142 A CN 201710473142A CN 107228785 A CN107228785 A CN 107228785A
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- China
- Prior art keywords
- humidification
- section
- heating kettle
- kettle body
- heater
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/44—Sample treatment involving radiation, e.g. heat
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
- G01N2001/2873—Cutting or cleaving
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The invention belongs to technical field of medical equipment, a kind of histogenic immunity groupization section humidification heater is disclosed, the steam outlet for being hinged on vapor delivery pipe front end is provided with；The end of vapor delivery pipe is hinged on the top of humidification heating kettle body；The inside of humidification heating kettle body is shelved with water level alarm；Temperature controller and dry burning resistance switch are pasted with the outer wall of the humidification heating kettle body；The inner bottom part of humidification heating kettle body shelves having heaters；Heater is connected with Foot-controlled switch by wire；The external bottom of humidification heating kettle is set with magnetic suction disc or silicon rubber suction cup；Water level alarm, dry combustion method switch, Foot-controlled switch connect temperature controller by wire.The vapor of the present invention keeps smooth 100% section, the about 90% wrinkle-free folding of section, about 80% section flawless, reduces the waste of precious tissue specimen, ensure that tissue cellularity is complete, reduce immunohistochemical staining and false positive occur to section warming and humidifying.
Description
Technical field
Used the invention belongs to Pathological Physiology technical field in Medical Devices, more particularly to a kind of section of histogenic immunity groupization
Humidify heater.
Background technology
At present, tissue should be also handled paraffin-embedded tissue block after being handled very well before being cut into slices, and be
More smooth section is obtained, and albumen can be kept to be difficult to be denatured, FFPE box is typically first placed in low temperature refrigerator, is made
Taken out again from low temperature refrigerator with preceding, but when starting section because wax stone temperature is low, indoor humidity is relatively low, and every cut out cuts
Easily there is crackle in the easy shrinkage of piece, out-of-flatness, causes bad ImmunohistochemistryResults Results.
In summary, the problem of prior art is present be：
In the existing group slicing treatment to histogenic immunity, it is impossible to ensure that every section is flat in immunohistochemical experiment slicing processes
It is whole, not shrinkage；The waste of precious tissue specimen can not be reduced and immunohistochemical staining is reduced and the phenomenon of false positive occur.
The content of the invention
The problem of existing for prior art, the invention provides a kind of histogenic immunity groupization section humidification heating dress
Put.
The present invention is achieved in that a kind of histogenic immunity groupization section humidification heater, the histogenic immunity group
Change section and the steam outlet for being hinged on vapor delivery pipe front end is provided with humidification heater；The vapor delivery pipe
End be hinged on humidification heating kettle body top；
The inside of the humidification heating kettle body is shelved with water level alarm；It is pasted with the outer wall of the humidification heating kettle body
Temperature controller and dry burning resistance switch；The inner bottom part of the humidification heating kettle body shelves having heaters；The heater is by leading
Line is connected with Foot-controlled switch；The external bottom of humidification heating kettle is set with magnetic suction disc or silicon rubber suction cup；It is the water level alarm, dry
Boiled pass, Foot-controlled switch connect temperature controller by wire.
Further, the vapor delivery pipe is free stretching structure.
Further, the openings of sizes of the front end of the steam outlet is a variety of, is shaped as circular or flat.
Further, it is coated with heat-insulation layer outside vapor delivery pipe.
Further, the pin steps on switch and is provided with multi gear, and the multi gear is connected by wire with temperature controller, for adjusting
Whole different temperatures.
Further, the outer bottom of the humidification heating kettle body is set with waterproof base.
Further, the external bottom of the humidification heating kettle is set with magnetic suction disc or silicon rubber suction cup；
Further, waterline is carved with the humidification heating kettle body, water level alarm is super to water level according to kettle body waterline
Cross or alarmed less than setting range.
Further, the temperature controller is respectively communicated with water level alarm, dry combustion method by way of singly-bound and many key combinations
Switch, Foot-controlled switch.
Further, the steam outlet is hinged in vapor delivery pipe by universal drive shaft；The temperature controller
Control range is 30 DEG C~60 DEG C；Magnetic suction disc or silica gel suction are set with for safety and stably in the outer bottom of humidification heating kettle body
Disk.
Further, the nut of adjustable position is inlaid with the humidification heating kettle body；Can with slicer bolt matching,
It may be mounted at slicer side or rear；The wet heating kettle body is transparent glassy layer or plastic layer cast structure.
Advantages of the present invention and good effect are：
Compared with the existing sectioning handled without warming and humidifying, the present invention adds before section to every section
Hot humidification process, cuts into slices immediately during warming and humidifying, start paster operation and exhibition piece operation, keep 100% section it is smooth, about 90%
Cut into slices wrinkle-free folding, about 80% section flawless, so as to reduce the waste of precious tissue specimen, ensure that tissue cellularity is complete,
Reduce immunohistochemical staining and false positive occur, it is ensured that the reliability and accuracy of ImmunohistochemistryResults Results.
Brief description of the drawings
Fig. 1 is histogenic immunity groupization section humidification heater schematic diagram provided in an embodiment of the present invention.
In figure：1st, vapor delivery pipe；2nd, steam outlet；3rd, humidification heating kettle body；4th, water level alarm；5th, temperature control
Instrument processed；6th, dry burning resistance switch；7th, heater；8th, Foot-controlled switch；9th, heat-insulation layer；10th, waterline；11st, waterproof base；12nd, power supply；
13rd, sucker or silicon rubber suction cup；14th, nut.
Embodiment
In order to further understand the content, features and effects of the present invention, hereby enumerating following examples, and coordinate accompanying drawing
Describe in detail as follows.
The structure to the present invention is explained in detail below in conjunction with the accompanying drawings.
As shown in figure 1, histogenic immunity groupization section humidification heater provided in an embodiment of the present invention, is set hinged
It is connected on the steam outlet 2 of the front end of vapor delivery pipe 1；The end of the vapor delivery pipe is hinged on humidification heating kettle body 3
Top；
The inside of the humidification heating kettle body 3 is shelved with water level alarm 4；Pasted on the outer wall of the humidification heating kettle body
There are temperature controller 5 and dry burning resistance switch 6；The inner bottom part of the humidification heating kettle body 3 shelves having heaters 7；The heater 7
Foot-controlled switch 8 is connected with by wire；The water level alarm, dry combustion method switch, Foot-controlled switch connect temperature control by wire
Instrument 5 processed.
The vapor delivery pipe 1 is free stretching structure.
The openings of sizes of the front end of the steam outlet 2 is a variety of.
Heat-insulation layer 9 is coated with outside vapor delivery pipe.
Plus the pin steps on switch 8 and is provided with multi gear.The multi gear is connected by wire with temperature controller, for adjusting not
It is synthermal.
The outer bottom of the humidification heating kettle body 3 is set with waterproof base 11；Water level is carved with the humidification heating kettle body
Line 10；The humidification heating kettle body is transparent glassy layer or plastic layer cast structure.
Water level alarm is alarmed water level according to kettle body waterline above or below setting range.
The temperature controller is respectively communicated with water level alarm, dry combustion method switch, pin by way of singly-bound and many key combinations
Control switch.
The steam outlet is hinged in vapor delivery pipe by universal drive shaft；The control range of the temperature controller
For 30 DEG C~60 DEG C；Magnetic suction disc or silicon rubber suction cup 13 are set with for safety and stably in the outer bottom of humidification heating kettle body.
The nut 14 of adjustable position is inlaid with the humidification heating kettle body；Can be with slicer bolt matching, can be with
Installed in slicer side or rear.
Heater 7 passes through wire connecting power 12.
The structure of the present invention is further described with reference to application method.
The present invention is in use, selection correct position, places humidification heating kettle body, vapor delivery pipe is installed, according to experiment
Demand adjusts the height and length of delivery pipe.
Switch on power master switch, is set according to environment temperature and other influence factors and adjusts temperature, makes the temperature of vapor
Degree is adapted to section and has no effect on chipping qualities.
When starting section, switch the presence or absence of switching vapor and size at any time can be stepped on by pin.
The opening of vapor delivery pipe can be arbitrarily sized, direction, and vapor delivery pipe can arbitrarily adjust length；
Vapor delivery pipe and warming and humidifying kettle body can adjust different directions and height；
Vapor delivery pipe can install heat-insulation layer additional, to prevent the unbalanced of temperature and scald operator；
The pin of warming and humidifying kettle body, which steps on switch, can adjust the severe degree of heating, control the size of vapor；
Water level alarm can destroy warming and humidifying kettle with controlling water level, anti-dry, influence immunohistochemical experiment；
The kettle body of warming and humidifying kettle can use visual material, can use scale, mark water level, be easy to observation, with
Anti-dry.
With reference to operation principle, the invention will be further described.
The present invention is in use, barreled mineral water is added in kettle, it is ensured that be added to more than waterline, debugs temperature detect switch (TDS), root
Corresponding heating-up temperature is set according to environment temperature and other influence factors, and adjusts the height and length of steam pipeline, water is steamed
Gas reaches the position of microtome just, begins to turn on power switch, and switch is stepped on by pin, and the conveying of steam is controlled at any time,
When steam starts to emerge, start section.
The vapor of the present invention keeps smooth 100% section, the about 90% wrinkle-free folding of section, about to section warming and humidifying
80% section flawless, reduces the waste of precious tissue specimen, ensures that tissue cellularity is complete, reduces immunohistochemical staining and goes out
Existing false positive.
It is described above to be only the preferred embodiments of the present invention, any formal limitation not is made to the present invention,
Every technical spirit according to the present invention is belonged to any simple modification made for any of the above embodiments, equivalent variations and modification
In the range of technical solution of the present invention.
Claims (10)
1. a kind of histogenic immunity groupization is cut into slices with humidification heater, it is characterised in that the histogenic immunity groupization section, which is used, to be added
Wet heater is provided with the steam outlet for being hinged on vapor delivery pipe front end；The end of the vapor delivery pipe is hinged
On the top of humidification heating kettle body；
The inside of the humidification heating kettle body is shelved with water level alarm；Temperature is pasted with the outer wall of the humidification heating kettle body
Controller and dry burning resistance switch；The inner bottom part of the humidification heating kettle body shelves having heaters；The heater is connected by wire
It is connected to Foot-controlled switch；The external bottom of humidification heating kettle is set with magnetic suction disc or silicon rubber suction cup；The water level alarm, dry combustion method are opened
Close, Foot-controlled switch connects temperature controller by wire.
2. histogenic immunity groupization section humidification heater as claimed in claim 1, it is characterised in that the vapor is defeated
It is free stretching structure to send pipe.
3. histogenic immunity groupization section humidification heater as claimed in claim 1, it is characterised in that the vapor goes out
The openings of sizes of the front end of mouth is a variety of, is shaped as circular or flat.
4. histogenic immunity groupization section humidification heater as claimed in claim 1, it is characterised in that vapor delivery pipe
Outside is coated with heat-insulation layer.
5. histogenic immunity groupization section humidification heater as claimed in claim 1, it is characterised in that the pin steps on switch
Multi gear is provided with, the multi gear is connected by wire with temperature controller, for adjusting different temperatures.
6. the histogenic immunity groupization section humidification heater described in claim 1, it is characterised in that the humidification heating kettle
The outer bottom of body is set with waterproof base.
7. the histogenic immunity groupization section humidification heater described in claim 1, it is characterised in that the humidification heating kettle
Waterline is carved with body, water level alarm is alarmed water level according to kettle body waterline above or below setting range.
8. histogenic immunity groupization section humidification heater as claimed in claim 1, it is characterised in that the temperature control
Instrument is respectively communicated with water level alarm, dry combustion method switch, Foot-controlled switch by way of singly-bound and many key combinations.
9. histogenic immunity groupization section humidification heater as claimed in claim 1, it is characterised in that the water vapour goes out
Mouth is hinged in vapor delivery pipe by universal drive shaft；The outer bottom of the humidification heating kettle body is set with magnetic suction disc or silica gel
Sucker.
10. histogenic immunity groupization section humidification heater as claimed in claim 1, it is characterised in that the humidification adds
The nut of adjustable position is inlaid with hot kettle body；The wet heating kettle body is transparent glassy layer or plastic layer cast structure.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710473142.3A CN107228785B (en) | 2017-06-21 | 2017-06-21 | Humidification heating device for tissue immunohistochemical section |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710473142.3A CN107228785B (en) | 2017-06-21 | 2017-06-21 | Humidification heating device for tissue immunohistochemical section |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107228785A true CN107228785A (en) | 2017-10-03 |
| CN107228785B CN107228785B (en) | 2023-08-01 |
Family
ID=59936068
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710473142.3A Active CN107228785B (en) | 2017-06-21 | 2017-06-21 | Humidification heating device for tissue immunohistochemical section |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107228785B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111458176A (en) * | 2020-06-03 | 2020-07-28 | 南通大学 | A section groove that is arranged in separation brain piece among electrophysiological experiment |
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2017
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| CN1312450A (en) * | 2001-02-28 | 2001-09-12 | 任春严 | Water and power saving device and method |
| CN1910449A (en) * | 2004-01-20 | 2007-02-07 | 三得利株式会社 | Gas detection method and detection device |
| JP2005274415A (en) * | 2004-03-25 | 2005-10-06 | Rigaku Corp | Thermal analysis apparatus and its water vapor generating apparatus |
| US20050223591A1 (en) * | 2004-04-08 | 2005-10-13 | Michel Huard | Method and system for the treatment of betula wood |
| JP2006116258A (en) * | 2004-10-21 | 2006-05-11 | Sky Net:Kk | Warming/humidifying container |
| CN102187292A (en) * | 2007-11-07 | 2011-09-14 | 奥特控制有限公司 | Liquid heating vessel and control |
| JP2009150864A (en) * | 2007-11-27 | 2009-07-09 | Seiko Instruments Inc | Device for humidifying embedding block, device for automatically producing thin slice, and device for automatically producing thin slice sample |
| CN203407891U (en) * | 2013-05-29 | 2014-01-29 | 常州市强辉电器有限公司 | Instant electric heating kettle |
| CN206026035U (en) * | 2016-04-29 | 2017-03-22 | 浙江绍兴苏泊尔生活电器有限公司 | Electric kettle |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111458176A (en) * | 2020-06-03 | 2020-07-28 | 南通大学 | A section groove that is arranged in separation brain piece among electrophysiological experiment |
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| Publication number | Publication date |
|---|---|
| CN107228785B (en) | 2023-08-01 |
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