CN107224301B - Quantitative or limited marrow fluid anticoagulation tube - Google Patents
Quantitative or limited marrow fluid anticoagulation tube Download PDFInfo
- Publication number
- CN107224301B CN107224301B CN201710609245.8A CN201710609245A CN107224301B CN 107224301 B CN107224301 B CN 107224301B CN 201710609245 A CN201710609245 A CN 201710609245A CN 107224301 B CN107224301 B CN 107224301B
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- cylinder
- pipeline
- main container
- circle center
- liquid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/0096—Casings for storing test samples
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
Abstract
The invention discloses a quantitative or limited bone marrow liquid anticoagulation tube, which is characterized in that a solid cylindrical conical plug which can be inserted into a liquid injection inlet of a pipeline arranged at the upper part of a cylinder is arranged at the circle center of the inner surface of an upper cover; a circle center through hole at the circle center of the cylinder is communicated with the pipeline liquid injection inlet, a vent hole is arranged at a position which is a certain distance away from the circle center of the cylinder, a hollow cylindrical pipeline is connected with the circle center through hole of the cylinder, and the length of the hollow cylindrical pipeline can reach the bottom of the inner pipe of the main container and slightly has a gap with the bottom of the inner pipe; the plastic membrane is arranged at a certain distance from the tail end of the hollow cylindrical pipeline, the plastic membrane is sleeved on the hollow cylindrical pipeline and can move upwards, after liquid is injected into the inner pipe of the main container, the plastic membrane slides upwards to touch the bottom surface of the cylinder and seal the vent hole, and the liquid is limited not to continuously enter the main container; the upper end and the lower end of the cylinder are screwed with the main container and the upper cover, so that the marrow puncture sampling and the long-distance specimen conveying are realized.
Description
Technical Field
The invention relates to an anticoagulation tube for bone marrow fluid, in particular to an anticoagulation tube for quantitative or limited bone marrow fluid.
Background
At present, no special marrow fluid anticoagulation tube for a marrow smear is clinically used, and marrow puncture sampling is used for morphologic examination specimens, and only instant sampling and instant smearing are available. Therefore, the preparation of the marrow fluid anticoagulant tube can realize marrow puncture sampling, smear separation and remote specimen conveying, can change the working mode of the current marrow puncture smear morphological examination is a task of the invention, can avoid a plurality of defects of the current working mode, and the contained anticoagulant marrow fluid can be used for manual smear and smear of marrow puncture specimens by a semi-automatic and full-automatic smear pushing machine.
Disclosure of Invention
The invention aims to provide a quantitative or limited bone marrow liquid anticoagulation tube which can realize bone marrow puncture sampling and smear separation and can remotely convey a specimen.
The invention aims to realize that the quantitative or limited bone marrow anticoagulation tube consists of an upper cover, a bone marrow injection and quantitative or limited device and a main container, and is characterized in that: the upper cover is a circular upper cover, and a solid cylindrical conical plug which can be inserted into a pipeline liquid injection inlet arranged at the upper part of the cylinder is arranged at the circle center of the inner surface of the upper cover; the bone marrow filling and quantifying or quantity limiting device comprises a cylinder, wherein the upper part of the cylinder is provided with a pipeline liquid filling body inlet, the circle center of the cylinder is provided with a circle center through hole, the circle center through hole is communicated with the pipeline liquid filling body inlet, a vent hole is arranged at a position which is a certain distance away from the circle center of the cylinder, a hollow cylindrical pipeline is connected with the circle center through hole of the cylinder, the diameter of the lower part of the hollow cylindrical pipeline is increased after the hollow cylindrical pipeline is arranged at a distance of 4MM of the circle center through hole of the cylinder, and the hollow cylindrical pipeline is manufactured to have a length which can extend to the bottom of an inner pipe of a main container and is slightly spaced from the bottom of the inner pipe; the plastic membrane is arranged at a certain distance from the tail end of the hollow cylindrical pipeline, is sleeved on the hollow cylindrical pipeline and can move upwards, and after liquid is injected into the inner pipe of the main container through the liquid injection inlet of the pipeline, the plastic membrane slides upwards under the action of liquid pressure to touch the bottom surface of the cylinder and seal the vent hole, so that the liquid is limited from continuously entering the inner pipe of the main container; the threads distributed on the upper end and the lower end of the cylinder are respectively used for being screwed on the main container and the upper cover.
The pipeline liquid injection opening can be connected with a liquid outlet of the injector, and the size of an interface of the pipeline liquid injection opening is matched with the liquid outlet of the injector.
The outer wall of the inner pipe and the inner wall of the main container are provided with a 1MM gap, the inner pipe vertically extends to the pipe bottom direction for 4MM, and the part below 4MM is a tapered arc bottom.
The invention has the advantages that: the bone marrow puncture smear machine can realize bone marrow puncture sampling and smear separation, can remotely convey specimens, can change the working mode of the conventional bone marrow puncture smear morphological examination, and avoids a plurality of defects of the current working mode. The anticoagulant marrow fluid contained in the invention can be used for manual smear and smear of marrow puncture specimen by semi-automatic and full-automatic smear pushing machines.
Drawings
Fig. 1 is a schematic perspective view of the present invention.
Fig. 2 is a schematic view of a structure in which the respective main components of fig. 1 are separated and distributed.
Fig. 3 is a full sectional view of fig. 1.
The numbering in the figures illustrates: 1. an upper cover; 2. a solid cylindrical conical plug; 3. a cylinder; 4. 3 air vents in total; 5. a thread; 6. a hollow cylindrical pipe; 7. a plastic film sheet; 8. a conduit liquid injection port; 9. a main container; 10. threads on the inside of the main vessel wall; 11. an inner tube.
Detailed Description
The invention is described in detail below with reference to the drawings and examples of the specification:
fig. 1 to fig. 3 are schematic diagrams illustrating an embodiment of an anticoagulant tube for quantifying or limiting bone marrow fluid according to the present invention.
A quantitative or limited bone marrow anticoagulation tube comprises an upper cover, a bone marrow injection and quantitative or limited device and a main container, wherein the specific structure of each part is as follows:
1) An upper cover: the circular upper cover 1 has a diameter (outer diameter) 16MM consistent with the outer diameter of the main container 1, a depth (measured on the outer wall) 8MM, a wall thickness of 1.5MM, an inner diameter 13MM, a thread depth of 2MM, and a solid cylindrical conical plug 2 with a diameter of 4MM and a length of 4MM arranged at the inner side of the center of the circle of the upper cover.
2) Bone marrow infusion and quantification or limiting devices: the diameter of the solid part of the part is the largest part, namely a cylinder 3 with the height of 16MM and the height of 5MM, the upper part of the cylinder 3 is provided with a pipeline liquid injection inlet 8, the center of circle of the cylinder 3 is provided with a center through hole 12, the center through hole is communicated with the pipeline liquid injection inlet 8, a vent hole 4 is arranged at a position with a certain distance away from the center of the cylinder 3, and the certain distance can be a specific numerical value such as 3.0MM, 4.0MM or 10MM, and the like, as long as the specific numerical value can be understood by a person skilled in the art; the invention leaves 1 air vent 4 at the position every 120 degrees apart from 3.0MM as radius from centre of a circle, 3 total, diameter 0.5MM, the upper and lower ends of cylinder distribute the screw thread 5 of height 2MM, the cylinder part diameter 13MM of the screw thread, use for connecting main container 9 and upper cover 1 (connect with screw thread respectively through the screw thread 5 that the upper and lower ends distribute, the upper end of a hollow cylindrical pipeline 6 terminates the centre of a circle through hole of the cylinder, the hollow cylindrical pipeline goes out the cylinder part to the end length is 15MM, leave the chink slightly with the bottom of inner tube 11; the plastic membrane 7 is arranged at a position 10MM away from the tail end of the pipeline, the plastic membrane 7 is sleeved on the hollow cylindrical pipeline 6 and can move upwards, after liquid is injected into the inner pipe 11 of the main container, the plastic membrane 7 can slide upwards due to the action of air pressure, the sliding distance is 4MM, the plastic membrane can touch the cylinder 3 and seal the vent hole 4, and the liquid cannot enter the inner pipe 11 of the main container 9 through the pipeline liquid injection inlet 8. (the ventilation hole of the cylinder is closed by the plastic membrane 7 of the hollow cylindrical pipe, the maximum amount of bone marrow liquid entering the main container is limited to 314 mu l), the diameter of the part of the hollow cylindrical pipe 6 in the cylinder is 1.5MM, the diameter of the part of the hollow cylindrical pipe 6 after the hollow cylindrical pipe exits from the cylinder to the plastic membrane 7 is increased to 2.0MM, and the length of the hollow cylindrical pipe 6 reaches the bottom of the main container and is slightly gapped with the bottom of the inner pipe 11. The pipeline liquid injection port can be connected with a liquid outlet of a 5/10ML syringe, the size of a connector of the pipeline liquid injection port is matched with the size of the liquid outlet of the syringe, the inner diameter is 4MM, the outer diameter is 6MM, and the height is 6MM, so that the bone marrow liquid can be injected into the main container through the connector.
3) A main container: the outer diameter of the main container 9 is 16MM, the wall thickness is 1.0MM, the height is 18MM, the thread 10 on the inner side of the main container wall has the depth of 2MM, the inner diameter of the inner tube is 10MM and the outer diameter of 12MM, a 1MM gap is left between the outer diameter of the inner tube and the inner wall of the main container, the inner diameter is 10MM, the length of the inner tube extending vertically to the tube bottom direction is 4MM, the part below 4MM can be in a tapered arc bottom, and the height is 11MM.
After the marrow liquid is injected into the main container and mixed with anticoagulant, the upper cover, the marrow injection and quantitative or limiting device and the main container are screwed together to form a completely closed container.
Claims (3)
1. A quantitative or limited bone marrow anticoagulation tube, which consists of an upper cover, a bone marrow injection and quantitative or limited device and a main container, and is characterized in that: the upper cover is a circular upper cover, and a solid cylindrical conical plug which can be inserted into a pipeline liquid injection port arranged at the upper part of the cylinder is arranged at the circle center of the inner surface of the upper cover; the bone marrow injection and quantification or quantity limiting device comprises a cylinder, wherein the upper part of the cylinder is provided with a pipeline liquid injection port, the circle center of the cylinder is provided with a circle center through hole, the circle center through hole is communicated with the pipeline liquid injection port, a vent hole is arranged at a position which is a certain distance away from the circle center of the cylinder, a hollow cylindrical pipeline is connected with the circle center through hole of the cylinder, the diameter of the lower part of the hollow cylindrical pipeline is increased after the hollow cylindrical pipeline is arranged at a distance of 4MM of the circle center through hole of the cylinder, and the manufactured length of the hollow cylindrical pipeline can extend to the bottom of an inner pipe of a main container and is slightly spaced from the bottom of the inner pipe; the plastic membrane is arranged at a certain distance from the tail end of the hollow cylindrical pipeline, the plastic membrane is sleeved on the hollow cylindrical pipeline and can move upwards, after liquid is injected into the inner pipe of the main container through the liquid injection port of the pipeline, the plastic membrane slides upwards under the action of liquid pressure to touch the bottom surface of the cylinder and seal the vent hole, and the liquid is limited not to continuously enter the inner pipe of the main container; the threads distributed on the upper end and the lower end of the cylinder are respectively used for being screwed on the main container and the upper cover; after the marrow liquid is injected into the main container and mixed with anticoagulant, the upper cover, the marrow injection and quantitative or limiting device and the main container are screwed together to form a completely closed container.
2. The anticoagulation tube for quantitative or limiting bone marrow fluid according to claim 1, characterized in that: the pipeline liquid injection port can be connected with a liquid outlet of the injector, and the size of a connector of the pipeline liquid injection port is matched with the size of the liquid outlet of the injector.
3. The quantitative or limiting bone marrow anticoagulant tube according to claim 1 or 2, wherein: the outer wall of the inner pipe and the inner wall of the main container are provided with a 1MM gap, the inner pipe vertically extends to the bottom of the inner pipe for 4MM, and the part below 4MM is a tapered arc bottom.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710609245.8A CN107224301B (en) | 2017-07-25 | 2017-07-25 | Quantitative or limited marrow fluid anticoagulation tube |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710609245.8A CN107224301B (en) | 2017-07-25 | 2017-07-25 | Quantitative or limited marrow fluid anticoagulation tube |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107224301A CN107224301A (en) | 2017-10-03 |
| CN107224301B true CN107224301B (en) | 2023-02-14 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710609245.8A Active CN107224301B (en) | 2017-07-25 | 2017-07-25 | Quantitative or limited marrow fluid anticoagulation tube |
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Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100466988C (en) * | 2003-08-25 | 2009-03-11 | 香港澳维有限公司 | Biological specimen collection and analysis system |
| EP1687620B1 (en) * | 2003-11-14 | 2014-04-23 | Alere Switzerland GmbH | Sample collection cup with integrated sample analysis system |
| JP5150507B2 (en) * | 2005-12-09 | 2013-02-20 | ディーエヌエー ジェノテック インク | Container system for storing substances so that they can be released |
| JP2007215835A (en) * | 2006-02-17 | 2007-08-30 | Olympus Biomaterial Corp | Bone marrow harvesting device and bone marrow harvesting method |
| BRPI1010798B8 (en) * | 2009-05-14 | 2021-07-27 | Dna Genotek Inc | closure for a container and sample collection method |
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| CN107224301A (en) | 2017-10-03 |
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