CN107213347A - 一种治疗骨折的骨科接骨膏药及其制备方法 - Google Patents
一种治疗骨折的骨科接骨膏药及其制备方法 Download PDFInfo
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Abstract
本发明涉及治疗骨折的骨科接骨膏药及其制备方法，可有效解决骨折的用药问题，其解决的技术方案是，该接骨膏药是由以下重量份数计的原料药物制成：骨碎补45‑55份、硼砂45‑55份、当归45‑55份、乳香20‑30份、没药20‑30份、川断45‑55份、自然铜45‑55份、大黄45‑55份、土鳖虫45‑55份、红花45‑55份、透骨草45‑55份、伸筋草45‑55份、川芎45‑55份、三七20‑30份、白及20‑30份和地龙20‑30份，本发明对于早期骨折不愈合、跌打损伤、扭伤和骨折等骨科疾病，对于治疗关节僵硬、股骨头缺血性坏死等骨折后遗症治疗效果好，无任何毒作用，并且能达到标本兼治的效果，是治疗骨折膏药上的创新。
Description
技术领域
本发明涉及医药领域，特别是一种治疗骨折的骨科接骨膏药及其制备方法。
背景技术
骨折是创伤外科常见病、多发病，其特点病情急伤情重，如无及时处理或处理不当可造成终生残疾甚至出现生命危险。传统西医治疗方法以手术复位内固定为主，传统中医以手法复位加外固定。通常需要制动并卧床休息60-90天，也就是像古人所描述的“伤筋动骨一百天”治愈骨折的规律，且时间长费用高给患者家庭和社会带来经济负担。因此，骨折药物上的改进是目前亟需解决的问题。
发明内容
针对上述情况，为解决现有技术之缺陷，本发明之目的就是提供一种治疗骨折的骨科接骨膏药及其制备方法，可有效解决骨折的用药问题。
本发明解决的技术方案是，该接骨膏药是由以下重量份数计的原料药物制成：骨碎补45-55份、硼砂45-55份、当归45-55份 、乳香20-30份、没药20-30份、川断45-55份、自然铜45-55份、大黄45-55份、土鳖虫45-55份、红花45-55份、透骨草45-55份、伸筋草45-55份、川芎45-55份 、三七20-30份、白及20-30份和地龙20-30份。
接骨膏药制备方法如下：将原料药物混合在一起，粉碎成细末，原料药物与灭菌用水按5：1比例搅拌均匀，放置微波炉加热10min，冷却，冷却后的原料与蜂蜜按比例4：1比例搅拌均匀成膏，再次放入微波炉加热10min，冷却后在医用膏药空白贴布上摊制成型，即得。
本发明选料讲究，原料易得，原料配比科学合理，制备方法简单，对于早期骨折不愈合、跌打损伤、扭伤和骨折等骨科疾病，对于治疗关节僵硬、股骨头缺血性坏死等骨折后遗症治疗效果好，无任何毒作用，并且能达到标本兼治的效果，是治疗骨折膏药上的创新。
具体实施方式
以下结合实施例对本发明的具体实施方式作进一步详细说明。
实施例1
本发明在具体实施时，可由以下重量份数计的原料药物制成：骨碎补46份、硼砂54份、当归46份 、乳香29份、没药21份、川断54份、自然铜46份、大黄54份、土鳖虫46份、红花54份、透骨草46份、伸筋草54份、川芎46份 、三七29份、白及21份和地龙29份。
实施例2
本发明在具体实施时，还可由以下重量份数计的原料药物制成：骨碎补50份、硼砂50份、当归50份、乳香25份、没药25份、川断50份、自然铜50份、大黄50份 、土鳖虫50份、红花50份、透骨草50份、伸筋草50份、川芎50份 、三七25份、白及25份和地龙25份。
实施例3
本发明在具体实施时，还可由以下重量份数计的原料药物制成：骨碎补54份、硼砂46份、当归54份 、乳香21份、没药29份、川断46份、自然铜54份、大黄46份、土鳖虫54份、红花46份、透骨草54份、伸筋草46份、川芎54份 、三七21份、白及29份和地龙21份。
本发明组分中：
骨碎补：功用主治：补肾，活血，止血。治肾虚久泻及腰痛，风湿痹痛，齿痛，耳鸣，跌打闪挫、骨伤，阑尾炎，斑秃，鸡眼。
硼砂：功能主治：外用清热解毒，消肿，防腐；内服清肺化痰。用于急性扁桃体炎，咽喉炎，咽喉肿痛，口舌生疮，口腔炎，齿龈炎，中耳炎，目赤肿痛，汗斑；内服用于痰热咳嗽，但现代少用。
当归：性味归经：性温，味甘、辛。归肝、心、脾经。功能主治：补血活血，调经止痛，润肠通便。用于血虚萎黄、眩晕心悸、月经不调、经闭痛经、虚寒腹痛、肠燥便秘、风湿痹痛、跌扑损伤、痈疽疮疡。
乳香：性味：辛苦，温。入心、肝、脾经。调气活血，定痛，追毒。治气血凝滞、心腹疼痛，痈疮肿毒，跌打损伤，痛经，产后瘀血刺痛。
没药：性味：苦，辛，平。生发固发，祛斑消痕，软坚除瘤，除癣愈创，固齿健龈，解毒等。治脱发毛细，黑斑伤痕，扁平疣，各种湿疹，牙龈糜烂，毒虫叮伤等。
川断：补肝肾；强筋骨；调血脉；续折伤；止崩漏。用于腰背酸痛；肢节痿痹；跌扑创伤、损筋折骨、胎动漏红、血崩、遗精、带下、痈疽疮肿。酒续断多用于风湿痹痛，跌扑损伤。盐续断多用于腰膝酸软。
自然铜：散瘀定痛、接骨续筋。治跌打损伤，筋断骨折，血瘀疼痛。
大黄：泄热毒，破积滞，行瘀血，主治：实热便秘；热结胸痞；湿热泻痢；黄疸；淋病；水肿腹满；小便不利；目赤；咽喉肿痛；口舌生疮；胃热呕吐；吐血；咯血；衄血；便血；尿血；蓄血；经闭；产后瘀滞腹痛；症瘕积聚；跌打损伤；热毒痈疡；丹毒；烫伤。
土鳖虫：咸，寒；有小毒。归肝经。破瘀血，续筋骨。用于筋骨折伤，瘀血经闭,症瘕痞块。
红花：活血通经、祛瘀止痛。用于痛经，经闭，产后血晕，瘀滞腹痛，胸痹心痛，血积，跌打瘀肿，关节疼痛，中风瘫痪。
透骨草：甘、辛，温。入肺、肝二经。祛风除湿，舒筋活络，活血止痛，解毒化疹，该品辛温，辛能行散，温胜寒湿。
伸筋草：祛风散寒，除湿消肿，舒筋活络。用于风寒湿痹，筋脉拘挛疼痈。外用治跌打扭伤肿痛。
川芎：活血祛瘀止痛，行气开郁，用于安抚神经，正头风头痛，症瘕腹痛，胸胁刺痛，跌扑肿痛，头痛，风湿痹痛。主治：治疗头痛之首选药物。月经不调；经闭痛经；产后瘀滞腥痛；症瘕肿块；胸胁疼痛；头痛眩晕；风寒湿痹；跌打损伤；痈疽疮疡。
三七：散瘀止血，消肿定痛。用于咯血，吐血，衄血，便血，崩漏，外伤出血，胸腹刺痛，跌仆肿痛。
白及：辛，苦、甘、涩，微寒。归肺、肝、胃经。收敛止血，消肿生肌。
地龙：性寒味咸。其味咸，性寒。功能为清热、息风、镇痉、通络、止喘、利尿。主治高热狂躁、惊风抽搐、头痛目赤、喘息痰热、中风、半身不遂等病证。
上述组份科学、合理配伍，互相支持，有效用于治疗骨折，疗效好，用药安全，并经临床资料得到了充分证明，有关临床资料如下：
1入选标准
选择临床骨折患者30例，其中，腰椎压缩骨折6例、上肢骨折5例、肋骨骨折6例、下肢骨折5例、骨折术后4例、跌打扭伤4例。
2疗效评定标准
1、局部无压痛及纵向叩击痛；2、局部无异常活动；3、X线显示骨折处有连续性骨痂，骨折线已模糊；4、拆除外固定后，如为上肢能向前平举1kg重物持续达1分钟；如为下肢不扶拐能在平地上连续步行30分钟，并不少于30步；5、连续观察2周骨折处不变形。
疗效评定：“治愈”临床症状消失，功能活动恢复正常，“显效”临床症状基本或大部分消失，“有效”临床症状明显好转或好转，“无效”临床症状体征无改变。
3治疗方案
本发明接骨膏药的使用方法：患处清洁处理，将膏药贴于患处，膏药贴规格160×120mm，有效成分10g，1贴3天，5贴1疗程，过敏体质慎用，孕妇慎用。
4统计学处理
骨折患者30例，3-10贴膏药治愈15例，显效10例，有效3例，无效2例，总有效率98％。表明本发明接骨膏药治疗骨科疼痛效果显著，达到了临床治疗目的，并且在治疗过程中，未见明显不良反应。
为了更详细的说明治疗情况，以下给出典型病例及治疗的疗效情况：
病例1、赵XX，女，38岁，职工，外伤致腰1椎体压缩骨折，腰背部疼痛，压痛明显。使用本发明膏药十贴，30天，疼痛症状消失，2个月后治愈，回单位后能正常上班。回访，疼痛无复发。
病例2、钱X，女，70岁，职工，郑州市人，行走时不慎摔倒，右手着地，至右腕关节克雷氏骨折，患者坚持保守治疗。后用本发明膏药6贴后，患者右腕关节疼痛肿胀明显缓解，右上肢活动自如，2个月后回访无明显异常。
病例3、周XX，女，43岁，职工，外伤致右肱骨近端骨折，右肩关节活动受限，因未伤及关节面，可行保守治疗，给予外展支架及用本发明膏药治疗45天，彻底治愈，不再疼痛，后期加强肩关节锻炼，右肩关节各活动度可，无明显疼痛。能下地劳动。1个月后回访无明显异常。
病例4，海X，男，30岁，自由职业，不慎扭伤致左踝关节疼痛肿胀，活动受限，X线时左腓骨远端骨折。因骨折断端移位不明显，使用本膏药5贴，20天症状基本消失，1个月后正常行走，X线显示骨折已愈合。1个月后回访无复发。
病例5、韦XX，女，58岁，郑州市人，因意外摔坏至左股骨粗隆间骨折，左髋关节疼痛肿胀，压痛明显。使用本发明膏药60天后，骨折处无疼痛肿胀，压痛不明显，X线显示骨折已愈合。2个月后回访无明显异常。
5结论
上述临床试验证明，本发明是治疗骨折的有效药物，疗效显著，无毒无副作用，治愈率高达98％，且材料简单易得，制作工艺简单，耗费成本低，对于早期骨折不愈合、跌打损伤、扭伤和骨折等骨科疾病，对于治疗关节僵硬、股骨头缺血性坏死等骨折后遗症治疗效果好，无任何毒作用，并且能达到标本兼治的效果，具有实际的临床意义和良好的推广应用价值。
Claims (5)
1.一种治疗骨折的骨科接骨膏药，其特征在于，该接骨膏药是由以下重量份数计的原料药物制成：骨碎补45-55份、硼砂45-55份、当归45-55份 、乳香20-30份、没药20-30份、川断45-55份、自然铜45-55份、大黄45-55份、土鳖虫45-55份、红花45-55份、透骨草45-55份、伸筋草45-55份、川芎45-55份 、三七20-30份、白及20-30份和地龙20-30份。
2.根据权利要求1所述的治疗骨折的骨科接骨膏药，其特征在于，由以下重量份数计的原料药物制成：骨碎补46份、硼砂54份、当归46份 、乳香29份、没药21份、川断54份、自然铜46份、大黄54份、土鳖虫46份、红花54份、透骨草46份、伸筋草54份、川芎46份 、三七29份、白及21份和地龙29份。
3.根据权利要求1所述的治疗骨折的骨科接骨膏药，其特征在于，由以下重量份数计的原料药物制成：骨碎补50份、硼砂50份、当归50份、乳香25份、没药25份、川断50份、自然铜50份、大黄50份 、土鳖虫50份、红花50份、透骨草50份、伸筋草50份、川芎50份 、三七25份、白及25份和地龙25份。
4.根据权利要求1所述的治疗骨折的骨科接骨膏药，其特征在于，由以下重量份数计的原料药物制成：骨碎补54份、硼砂46份、当归54份 、乳香21份、没药29份、川断46份、自然铜54份、大黄46份、土鳖虫54份、红花46份、透骨草54份、伸筋草46份、川芎54份 、三七21份、白及29份和地龙21份。
5.权利要求1或2-4任一项所述的治疗骨折的骨科接骨膏药的制备方法，其特征在于，将原料药物混合在一起，粉碎成细末，原料药物与灭菌用水按5：1比例搅拌均匀，放置微波炉加热10min，冷却，冷却后的原料与蜂蜜按比例4：1比例搅拌均匀成膏，再次放入微波炉加热10min，冷却后在医用膏药空白贴布上摊制成型，即得。
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Application publication date: 20170929 |