CN107213111A - A kind of manufacture method for the suppository for treating vaginitis - Google Patents
A kind of manufacture method for the suppository for treating vaginitis Download PDFInfo
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- CN107213111A CN107213111A CN201710315367.6A CN201710315367A CN107213111A CN 107213111 A CN107213111 A CN 107213111A CN 201710315367 A CN201710315367 A CN 201710315367A CN 107213111 A CN107213111 A CN 107213111A
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- Prior art keywords
- suppository
- salt
- manufacture method
- carbon material
- carbon
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/34—Copper; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/38—Silver; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a kind of manufacture method for the suppository for treating vaginitis, it comprises the following steps：First carbon material leaching is placed in the aqueous solution of active component salt；Then in the heated drying aqueous solution at 60 to 500 DEG C, the agglomerate of active component salt is made to be attached on carbon material；Then the agglomerate of the active component salt on carbon material is attached in thermal cracking at 200 to 1000 DEG C, to be reduced into active particle and be attached on carbon material；Then the carbon material for being attached with active particle is mixed with bolt with matrix, to obtain mixture；Finally by mixture solidification forming, the suppository for the vaginitis that obtains medical treatment.
Description
Technical field
The present invention relates to a kind of manufacture method of suppository, and more particularly to a kind of manufacturer for the suppository for treating vaginitis
Method.
Background technology
Vaginitis is the common multiple diseases of women, is divided into according to the pathogenic origin cause of formation：Bacterial vaginitis, monilial vagina
Inflammation, trichomonas vaginitis, senile vahinitis, infantile vaginitis.If vaginitis not properly treatment, may be with vagina wound
Or the symptom such as cervix erosion.The medicine for the treatment of vaginitis has antibiotic external preparation and antibiotic oral formulations, external application at present
Preparation is more with lotion, suppository or effervesce sheet form.Although these formulations have certain curative effect, antibiotic is also easy to produce the resistance to the action of a drug
And probably can cause side effect.
Chinese invention patent application (publication number CN105434334A) proposes a kind of manufacture method of non-antibiotic suppository.Tool
For body, it is a kind of manufacture method of activated carbon suppository, and detailed step is as follows：By 98 to 102 parts of water, 0.4 to 0.6 part of nm
The silver-colored aqueous solution and 0.8 to 1.2 part of carbomer are uniformly mixed and heated to after 65 to 75 DEG C, add 5 to 7 parts of fatty acid mixeds sweet
Grease is simultaneously uniformly mixed, and obtains mixed solution；By 3 to 5 parts of sodium carboxymethylcelluloses, 6 to 9 parts of hydroxypropyl celluloses, with 78 to
82 parts of activated carbon uniformly after mixing, add above-mentioned mixed solution, and stir into dough；After pressurization injection mould, freezing is kept
Shape is simultaneously stripped taking-up；In heating 2 to 6 hours at 65 to 85 DEG C, heating 0.5 to 2.5 hour at 105 to 115 DEG C, finally
Wrap up medical absorbent cotton/gauze.However, the activated carbon suppository only part nm silver in above-mentioned technical proposal is attached on activated carbon, separately
Outer a part of nm silver is free, thus can not bacterium effectively processed to reach the purpose for the treatment of vaginitis.Moreover, free nm
Silver is also possible to trigger allergy, or even causes toxicity.In addition, the manufacture method of above-mentioned technical proposal can not make activated carbon suppository quality
It is maintained to a certain degree, so being unsuitable for extensive manufacture.
Therefore, the manufacture method for the activated carbon suppository of known treatment vaginitis proposes to improve, and is this area skill really
One of problem that art personnel/or practitioner actively solve.
The content of the invention
Goal of the invention：The first object of the present invention is to propose a kind of manufacture method of suppository, and the suppository of gained can be effective
Ground bacterium is to treat vaginitis.
Another object of the present invention is to propose a kind of manufacture method of suppository, the suppository of gained triggers without free nm silver
Allergy or toxicity problem.
A further object of the present invention is to propose a kind of manufacture method of suppository, the suppository uniform quality of gained so that this
Method is suitable to extensive manufacture.
Technical scheme：A kind of manufacture method for the suppository for treating vaginitis, comprises the following steps：
The leaching of one carbon material is placed in the aqueous solution of active component salt at least 1 minute；
The heated drying aqueous solution at least 1 minute at 60 to 500 DEG C, makes the agglomerate of active component salt be attached to carbon material
On；
The agglomerate of thermal cracking active component salt at least 1 minute at 200 to 1000 DEG C, to by active component salt
Agglomerate is reduced into an active particle and is attached on carbon material；
The carbon material for being attached with active particle is mixed with bolt with matrix, mixture is obtained, wherein, adhere to active
The carbon material of grain is (0.001~20) with the mass ratio of bolt matrix:100；And
By mixture solidification forming, the suppository for the vaginitis that obtains medical treatment.
Further, following steps are further included between cracking step and blend step：
Carbon material is cleaned at least 1 minute with water；And
The heated drying carbon material at least 1 minute at 60 to 500 DEG C.
Further, the carbon material is activated carbon fiber, carbon fiber, activated carbon powder, charcoal, bamboo charcoal grain, carbon black, graphite
The carbon dust that carbon dust, the artificial resin that powder, carbon nanotube, nm carbon dust, graphene, expanded graphite powder, phenolic resin are made are made
In one or more.
Further, active component salt be silver salt, mantoquita, gold salt, palladium salt, zinc salt, platinum salt, aluminium salt, nickel salt, cobalt salt,
One or more in silicon salt, calcium salt, titanium salt, chromic salts.
Further, bolt is grease type matrix or water-soluble and hydrophilic matrix with matrix.
Further, leaching is put step and carried out under normal temperature and pressure or under vacuum or under stirring condition.
Further, the aqueous solution of active component salt also contains in a polar solvent, the mixed liquor of polar solvent and water
Polar solvent accounting is 5~70wt%.
Further, the polar solvent is one kind in alcohols, aldehydes, ketone, ethers.
Further, cracking step is to be carried out in the presence of vacuum or nitrogen or inert gas.
Further, blend step is further included：
The carbon material, bolt matrix, the antibiotic that are attached with active particle are mixed, mixture is formed.
Beneficial effect：A kind of manufacture method of suppository for treating vaginitis disclosed by the invention has the advantages that：
1st, active particle can be allowed to be evenly affixed on carbon material, so that when suppository is placed on intravaginal, vagina is contacted with suppository
The inactive uneven problem of contact number of particle mesh in position.Such a phenomenon can make suppository to the bacterium effect one processed of contact site
Cause；
2nd, the amount for the active particle that dissociates in suppository can be reduced, so that suppository can reduce allergy or toxicity when being placed on intravaginal
Occur；
3rd, suppository uniform quality can be allowed, for the large-scale production of suppository.
Brief description of the drawings
Fig. 1 is a kind of flow chart of the manufacture method for the suppository for treating vaginitis disclosed by the invention.
Embodiment：
To allow above-mentioned and/or other purposes of the invention, effect, feature to become apparent, better embodiment cited below particularly,
Elaborate under：
As shown in figure 1, a kind of manufacture method for the suppository for treating vaginitis, contains following steps：
(S1), first time heated drying (S2), thermal cracking (S3), washing (S4), second heated drying (S5), mixing are put in leaching
And solidification forming (S7) (S6).
A kind of manufacture method for the suppository for treating vaginitis, comprises the following steps：
S1 leachings are put
The leaching of one carbon material is placed in concentration with least 1 point in the aqueous solution of 0.00001M to a 20M active component salt
Clock, preferably 1 to 800 minute；
S2 first time heated dryings
The aqueous solution in heated drying step S1 at 60 to 500 DEG C at least 1 minute, preferably 1 to 800 minute, it can make work
The agglomerate of property composition salt is attached on carbon material；
S3 thermal crackings
The agglomerate of active component salt in cracking step S2 at 200 to 1000 DEG C at least 1 minute, preferably 1 to 800
Minute, the agglomerate of active component salt is reduced into an active particle and is attached on carbon material；
S6 is mixed
The carbon material for being attached with active particle is mixed with bolt with matrix, mixture is obtained, wherein：
It is (0.001~20) that the carbon material of active particle, which is attached with, with the mass ratio of bolt matrix:100；
S7 solidification formings
By mixture solidification forming, mixture when carrying out this step, is maintained at low temperature by the suppository for the vaginitis that obtains medical treatment
Under.
Further, following steps are further included between step S3 and step S6
S4 is washed
Carbon material is cleaned at least 1 minute with water, preferably 5 to 480 minutes, it can remove free activity from carbon material
The amount of free active particle, when carrying out this step, can rush carbon materials parison in water or with water in grain, the suppository to reduce gained
Wash；
Second of heated drying of S5
In heated drying carbon material at 60 to 500 DEG C at least 1 minute, preferably 1 to 800 minute, this can remove moisture of residual.
Further, step S1 is in carrying out this step under normal temperature and pressure or vacuum or stirring condition, and wherein vacuum is with stirring
Condition can prevent capillarity, to allow active component salt to be uniformly distributed in the aqueous solution.
Further, carbon material is cleaned 10 to 240 minutes with water in step S4.
Further, in heated drying carbon material 5 to 240 minutes at 60 to 500 DEG C in step S5.
Further, carbon material leaching is placed in the aqueous solution of an active component salt 5 to 240 minutes in step S1.
Further, to assist salt to be uniformly distributed in the aqueous solution, the aqueous solution is except water and active component in step S1
Outside salt, an also polar solvent, on the basis of the gross weight of water and polar solvent, polar solvent can account for 5wt% to 70wt%.
Further, polar solvent is one kind in alcohols, aldehydes, ketone, ethers.
Further, carbon material be activated carbon fiber, carbon fiber, activated carbon powder, charcoal, bamboo charcoal grain, carbon black, graphite powder,
In the carbon dust that carbon dust, the artificial resin that carbon nanotube, nm carbon dust, graphene, expanded graphite powder, phenolic resin are made are made
It is one or more of.
Further, active component salt be silver salt, mantoquita, gold salt, palladium salt, zinc salt, platinum salt, aluminium salt, nickel salt, cobalt salt,
One or more in silicon salt, calcium salt, titanium salt, chromic salts.
Further, active component salt includes the acetate of active component (such as：Silver acetate), nitrate (such as：Nitric acid
Silver, copper nitrate or zinc nitrate), phosphate (such as：Silver orthophosphate) or sulfonate is (such as：Sulfonic acid silver).
Further, in step S2, the aqueous solution is maintained at 60 to 500 DEG C 5 to 240 minutes.
Further, in step S3, and on the basis of the weight of carbon material, active particle can account for the weight of carbon material
Less than 50%, preferably 0.0001% to 25%.
Further, step S3 can be carried out in the presence of vacuum or nitrogen or inert gas.
Further, the agglomerate for active component salt on the carbon material being adhered in step S3 is maintained at 200 to 1000 DEG C
Lower thermal cracking 5 to 240 minutes.
Further, bolt matrix includes grease type matrix or water-soluble and hydrophilic matrix in step S6, wherein：
Grease type matrix is cocoa butter, semi-synthetic fatty glyceride or fully synthetic fatty glyceride；And it is semi-synthetic
Fatty glyceride can be such as semi-synthetic cocounut oil ester, the grey grease in semi-synthetic mountain or semi-synthetic palm grease, fully synthetic fatty acid glycerine
Ester can be such as propylene glycol stearate；
Water-soluble is glycerin gelatine or polyethylene glycol with hydrophilic matrix.
Further, it is the bacterium effect processed of the suppository obtained by increase, the carbon of active particle can will be more attached with step S6
Material, bolt matrix, antibiotic mixing, form mixture.
Further, antibiotic be Metronidazole azoles (metronidazole), clindomycin (clindamycin),
Gram appropriate gram that frustrate (butoconazole), the mould azoles of gram chlorine (clotrimazole), miaow and can receive azoles (miconazole), the rhzomorph of resistance to silk
(nystatin) but, control that azoles (tioconazole), Te Kangna azoles (terconazole) but that frustrate in (econazole)
It is a kind of.
Hereby with following embodiments, embodiment of above is illustrated：
Preparation example 1
It is activated carbon fiber cloth (platform carbon science and technology share first there is provided a polyacrylonitrile (polyacrylonitrile, PAN)
Co., Ltd), feature is as follows：BET specific surface area 1,600m2/ g, density 2.09g/cm3, carbon content 85wt%；
Then, activated carbon fiber cloth is immersed in 0.1M silver nitrate aqueous solutions after 5 hours,
In heated drying silver nitrate aqueous solution 2 hours at 80 DEG C, make silver nitrate formation agglomerate and be attached to activated carbon fiber cloth
On；
The silver nitrate agglomerate on activated carbon fiber cloth is attached to thermal cracking in the presence of nitrogen in 400 DEG C, makes nitric acid banking group
Block is reduced into Argent grain and is attached on activated carbon fiber cloth；
Afterwards, activated carbon fiber cloth is sequentially obtained into a composition through washing, dry, grinding, with sieving, this composition contains
Active carbon dust and Argent grain attached to it, its feature are as follows：BET specific surface area 1,220m2/ g, density 2.13g/cm3,
Silver content 0.03wt%.
Then, after 10 grams of fatty glycerides, 5 grams of hydroxypropyl celluloses and 1 gram of composition are uniformly mixed, heating mixing
Thing is to 65 DEG C and pressurizes in injection mould.Finally, cooling mixture is into multiple suppositorys, and each suppository weight 2.5g contains 0.156 gram
Composition, accounts for the 6.25% of suppository.
Preparation example 2
First there is provided a polyacrylonitrile activated carbon fiber cloth (Tai Tan Science and Technology Co., Ltd.), feature is as follows：BET
Specific surface area 1,600m2/ g, density 2.09g/cm3, carbon content 85wt%；
Then, activated carbon fiber cloth is immersed in 0.1M silver nitrates and 0.1M copper nitrate aqueous solutions after 5 hours,
In heated drying activity silver nitrate and copper nitrate aqueous solution 2 hours at 80 DEG C, silver nitrate is set to be formed respectively with copper nitrate
Agglomerate is simultaneously attached on activated carbon fiber cloth；
In 400 DEG C with thermal cracking is attached to silver nitrate agglomerate and copper nitrate on activated carbon fiber cloth respectively in the presence of nitrogen
Agglomerate, makes silver nitrate agglomerate be reduced into Argent grain and copper particle with copper nitrate group and be attached on activated carbon fiber cloth；
Afterwards, activated carbon fiber cloth is sequentially obtained into a composition through washing, dry, grinding, with sieving, this composition contains
Active carbon dust and Argent grain attached to it and copper particle, its feature are as follows：BET specific surface area 1,200m2/ g, density
2.13g/cm3, silver content 0.03wt%, copper content 0.05wt%；
Then, after 10 grams of fatty glycerides, 5 grams of hydroxypropyl celluloses and 1 gram of composition are uniformly mixed, heating mixing
Thing is to 65 DEG C and pressurizes in injection mould.Finally, cooling mixture is into multiple suppositorys, and each suppository weight 2.5g contains 0.156 gram
Composition, accounts for the 6.25% of suppository.
Preparation example 3
First there is provided a vegetable active carbon dust, feature is as follows：BET specific surface area 800m2/g；
Then, in activated carbon powder being immersed under vacuum in 0.1M silver nitrate aqueous solutions after 5 hours,
In heated drying silver nitrate aqueous solution 2 hours at 80 DEG C, make silver nitrate formation agglomerate and be attached on activated carbon powder；
The silver nitrate agglomerate on activated carbon powder is attached to thermal cracking in the presence of nitrogen in 400 DEG C, makes silver nitrate agglomerate also
Original is into Argent grain and is attached on activated carbon powder；
Afterwards, activated carbon powder is sequentially obtained into a composition through washing, dry, grinding, with sieving, this composition contains work
Property carbon dust and Argent grain attached to it, its feature is as follows：BET specific surface area 780m2/ g, silver content 0.02wt%；
Then, by follow-up gained mixture weight, take 17% gelatin to be mixed with 28% water, then with 54% glycerine and
1% composition is mixed.In heating mixture to 65 DEG C and pressurize injection mould in after, cooling mixture into multiple suppositorys, it is each
Suppository weight 15g, containing 0.15 gram of composition, accounts for the 1% of suppository.
Comparative example 1
After 10 grams of fatty glycerides, 5 grams of hydroxypropyl celluloses and 1 gram of polyacrylonitrile activated carbon fiber are uniformly mixed,
Mixture is heated to 65 DEG C and is pressurizeed in injection mould.Finally, cooling mixture is into multiple suppositorys, and each suppository weight 2.5g contains
There is 0.156 gram of activated carbon fiber, account for the 6.25% of suppository.
Comparative example 2
By the weight of the mixture of follow-up gained, take 17% gelatin to be mixed with 28% water, then with 54% glycerine and 1% plant
Activated carbon powder is mixed.After heating mixture is to 65 DEG C and in the injection mould that pressurizes, cooling mixture is into multiple suppositorys, Mei Yishuan
Agent weight 15g, containing 0.15 gram of vegetable active carbon dust, accounts for the 1% of suppository.
Comparative example 3
This comparative example is to implement with reference to China's Mainland patent of invention publication number CN105434334A.First, 0.5 gram is added
The aqueous solution is into 100 grams of water and uniformly mixes for nm silver.It is heated to after 70 DEG C, adds 6 grams of fatty acid mixeds water-soluble to nm silver
In liquid, to obtain a mixed solution.Add 4 grams of sodium carboxymethylcelluloses, 7 grams of low-substituted hydroxypropyl celluloses and 80 grams of activity
Carbon is to mixed solution and uniform stirring into a dough.Finally, dough is injected in mould and is cooled to multiple bolts
Agent.
Analyze example
According to the chemical antibacterial test method of association -100 of U.S. textile, take the suppository of 0.2 gram of each example and different strain culture 24 small
When to carry out bacteriostatic test.As a result as shown in table 1, can learn the suppository of each preparation example has the system of the suppository better than each comparative example
Bacterium effect.
It should be noted that, through comparing preparation example 1 to 3 and comparative example 1,2, it is known that Argent grain or copper particle can be changed into sun from
Son (Ag+Or Cu+、Cu2+), and killed through these cations except bacterium.Through comparing preparation example 1 to 3 and comparative example 3, it is known that different
Processing procedure the bacterium effect processed of the suppository of argentiferous composition can be caused different.
The 24 hours bacterium effects processed of suppository obtained by table 1, each example to different strain
To sum up, the method described in present embodiment can allow active particle to be evenly affixed on carbon material, so that suppository is placed on
During intravaginal, the inactive uneven problem of contact number of particle mesh in position that vagina is contacted with suppository.Such a phenomenon can make suppository
Bacterium effect processed to contact site is consistent.In addition, the method can reduce the amount for the active particle that dissociates in suppository, so that suppository is placed on
The generation of allergy or toxicity can be reduced during intravaginal.Also, the method can allow suppository uniform quality, for the extensive of suppository
Production.
In summary, above-mentioned specific embodiment is only presently preferred embodiments of the present invention, but can not limit the present invention with this
The scope of implementation；Therefore, all simple equivalent changes made according to scope of the present invention patent and description of the invention content are with repairing
Decorations, are all still remained within the scope of the patent.
Claims (10)
1. a kind of manufacture method for the suppository for treating vaginitis, it is characterised in that including：
The leaching of one carbon material is placed in the aqueous solution of active component salt at least 1 minute；
The heated drying aqueous solution at least 1 minute at 60 to 500 DEG C, makes the agglomerate of active component salt be attached on carbon material；
The agglomerate of thermal cracking active component salt at least 1 minute at 200 to 1000 DEG C, to by the agglomerate of active component salt
It is reduced into an active particle and is attached on carbon material；
The carbon material for being attached with active particle is mixed with bolt with matrix, mixture is obtained, wherein, it is attached with active particle
Carbon material and the mass ratio of bolt matrix are (0.001~20):100；And
By mixture solidification forming, the suppository for the vaginitis that obtains medical treatment.
2. a kind of manufacture method for the suppository for treating vaginitis as claimed in claim 1, it is characterised in that cracking step with
Following steps are further included between blend step：
Carbon material is cleaned at least 1 minute with water；And
The heated drying carbon material at least 1 minute at 60 to 500 DEG C.
3. a kind of manufacture method for the suppository for treating vaginitis as claimed in claim 1, it is characterised in that the carbon material is
Activated carbon fiber, carbon fiber, activated carbon powder, charcoal, bamboo charcoal grain, carbon black, graphite powder, carbon nanotube, nm carbon dust, graphene,
One or more in the carbon dust that carbon dust that expanded graphite powder, phenolic resin are made, artificial resin are made.
4. a kind of manufacture method for the suppository for treating vaginitis as claimed in claim 1, it is characterised in that active component salt
For one kind in silver salt, mantoquita, gold salt, palladium salt, zinc salt, platinum salt, aluminium salt, nickel salt, cobalt salt, silicon salt, calcium salt, titanium salt, chromic salts or
It is several.
5. a kind of manufacture method for the suppository for treating vaginitis as claimed in claim 1, it is characterised in that bolt is oil with matrix
Lipid matrix or water-soluble and hydrophilic matrix.
6. a kind of manufacture method for the suppository for treating vaginitis as claimed in claim 1, it is characterised in that leaching puts step in normal
Carried out under normal temperature and pressure or under vacuum or under stirring condition.
7. a kind of manufacture method for the suppository for treating vaginitis as claimed in claim 1, it is characterised in that active component salt
The aqueous solution also to contain polar solvent accounting in a polar solvent, the mixed liquor of polar solvent and water be 5~70wt%.
8. a kind of manufacture method for the suppository for treating vaginitis as claimed in claim 7, it is characterised in that the polar solvent is
One kind in alcohols, aldehydes, ketone, ethers.
9. a kind of manufacture method for the suppository for treating vaginitis as claimed in claim 1, it is characterised in that cracking step is
Carried out in the presence of vacuum or nitrogen or inert gas.
10. a kind of manufacture method for the suppository for treating vaginitis as claimed in claim 1, it is characterised in that blend step is more
Including：
The carbon material, bolt matrix, the antibiotic that are attached with active particle are mixed, mixture is formed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710315367.6A CN107213111A (en) | 2017-05-08 | 2017-05-08 | A kind of manufacture method for the suppository for treating vaginitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710315367.6A CN107213111A (en) | 2017-05-08 | 2017-05-08 | A kind of manufacture method for the suppository for treating vaginitis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107213111A true CN107213111A (en) | 2017-09-29 |
Family
ID=59945243
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710315367.6A Pending CN107213111A (en) | 2017-05-08 | 2017-05-08 | A kind of manufacture method for the suppository for treating vaginitis |
Country Status (1)
| Country | Link |
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| CN (1) | CN107213111A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1480584A (en) * | 2002-09-06 | 2004-03-10 | 刘维春 | Method for preparing antibacterial material by combining nano silver and activated carbon |
| TW591155B (en) * | 2003-06-20 | 2004-06-11 | Univ Feng Chia | Method for producing product from active carbon fiber loaded with silver |
| TW201132341A (en) * | 2010-03-22 | 2011-10-01 | Univ Feng Chia | Medicine compositions for treating urinary system |
| CN105434334A (en) * | 2015-12-18 | 2016-03-30 | 上海韬鸿化工科技有限公司 | Active carbon suppository used for treating cervical erosion, and preparation method thereof |
-
2017
- 2017-05-08 CN CN201710315367.6A patent/CN107213111A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1480584A (en) * | 2002-09-06 | 2004-03-10 | 刘维春 | Method for preparing antibacterial material by combining nano silver and activated carbon |
| TW591155B (en) * | 2003-06-20 | 2004-06-11 | Univ Feng Chia | Method for producing product from active carbon fiber loaded with silver |
| TW201132341A (en) * | 2010-03-22 | 2011-10-01 | Univ Feng Chia | Medicine compositions for treating urinary system |
| CN105434334A (en) * | 2015-12-18 | 2016-03-30 | 上海韬鸿化工科技有限公司 | Active carbon suppository used for treating cervical erosion, and preparation method thereof |
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Application publication date: 20170929 |