CN107212158A - A kind of nutrient fortified health-care type premix for preventing and treating sow cracked feet disease - Google Patents

A kind of nutrient fortified health-care type premix for preventing and treating sow cracked feet disease Download PDF

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CN107212158A
CN107212158A CN201710538134.2A CN201710538134A CN107212158A CN 107212158 A CN107212158 A CN 107212158A CN 201710538134 A CN201710538134 A CN 201710538134A CN 107212158 A CN107212158 A CN 107212158A
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sow
cracked feet
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health
vitamin
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刘影
卢红卫
张俊平
高永胜
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Beijing Challenge Husbandry Science & Technology Co Ltd
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Beijing Challenge Husbandry Science & Technology Co Ltd
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
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    • A23K20/142—Amino acids; Derivatives thereof
    • A23K20/147—Polymeric derivatives, e.g. peptides or proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
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    • A23K20/158—Fatty acids; Fats; Products containing oils or fats
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    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968—Ophiopogon (Lilyturf)
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    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969—Polygonatum (Solomon's seal)
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Abstract

The present invention relates to a kind of nutrient fortified health-care type premix for preventing and treating sow cracked feet disease, every kilogram of nutrient fortified health-care type premix is consisted of the following composition：The 350g of bovine spinal cord protein peptone 300, the 200g of oat 150, the 40g of brown sugar 20, emulsified fish oil lard compound 100 150g, the 30g of seawood meal 10, the 36.3g of B B-complex 33.8, compound organic trace element 39 65g, the 25g of chitosan oligosaccharide 15, the Poria cocos-Radix Astragali-tuber of dwarf lilyturf-Rhizoma Polygonati Odorati extract 5g, surplus is fermented bean dregs, is uniformly mixed into by 1% adding proportion in the sow diets for occurring cracked feet disease.The nutrient fortified health-care type premix of the preventing and treating sow cracked feet disease of the present invention, for the sick pathogenesis, sow constitution is adjusted from nutrition, fundamentally adjust the immunocompetence and wound-healing abilities of sow, so as to the problem of solving sow cracked feet, effect is more much better than zinc supplementation and effects of antibiotics, the disorderly metabolism of cracked feet sow is adjusted normal by the health premix of the technical program, the later stage is uneasy to recur.

Description

A kind of nutrient fortified health-care type premix for preventing and treating sow cracked feet disease
Technical field
The present invention relates to livestock-raising field of feed, and in particular to a kind of fortification of preventing and treating sow cracked feet disease is protected Strong type premix.
Background technology
In recent years, with the continuous expansion of animal husbandry, the intensive pig farm of scale turn into new developing direction, but with This has sow the phenomenons such as arthrocele, the cracking of hoof hyperkeratosis, coffin rupture occur often simultaneously, in large-scale pig farm, causes Sow production performance declines, and eliminates too early, larger economic loss is brought to pig farm.This distinctive limb of Large-scale pig farm Hoof disease is referred to as " cracked feet disease ", it is considered that relevant with some nutrient shortages, and the sow of coffin rupture is highly susceptible to disease Opportunistic pathogen infection develops into " rotten hoof disease ", and pig farm normal handling method is based on zinc supplementation and antibiotic therapy, but easily recurrence, Therefore regulation and control are carried out from diet nutrient and is only the method really effected a permanent cure.
The pathogenic factor of cracked feet disease is more complicated, for breed breeding, and people only pursue high lean meat percentage, grow fast, body weight Increase the performance such as fast, have ignored the development of limb hoof, cause part sow limb hoof development very thin not strong enough, it is difficult to which support is developed very fast Body weight, cause limb hoof excessively to bear a heavy burden, occur hoof wound, such as sand crack, Landrace, great Bai, Duroc etc., especially young Landrace Multiple, particularly replacement gilt and sow pig are tender and lovely due to hoof pad, it is easier to which that frayed infection, and hoof tips matter cracking, coffin is broken Split, and influence production performance, cause to eliminate in advance.For trophic factor, the nutrition of sow feed is unbalanced or deficiency, easily leads Cause this sick generation.Calcium phosphorus in such as feed is not enough or ratio is improper, when particularly phosphorus is not enough, easily causes hoof bottom and splits；Selenium deficiency can Cause arthritis, hoof deformation, muscular atrophy；Scarce biotin can cause hoof transverse fissure, and hoof bottom is easy to wear.Lack vitamin D, sulphur, zinc, The cuticula intensity and hardness of hoof can not be maintained when manganese and copper etc., pig body metabolic dysfunction is slow-growing, occur coffin and split Open, bleeding infection, the disease such as depilation.In addition, colony house earth construction and sanitary condition is good, sow lacks motion and illumination, pig house Insulation is unsound, stocking density is excessive causes pig is crowded to sting bucket etc., can all cause this disease to occur.When epidemic disease occurs for pig farm When disease, such as aftosa, streptococcal arthritis, erysipelas arthritis, mycoplasma arthritis, haemophilus property arthritis are sick The impaired morbidity of hoof can be caused.
In cultivation site, some prophylactico-therapeutic measures are also taken, including the attention rate to hoof is improved during seed selection, daily ration is improved Nutrient balance, improve the friction condition and gradient in circle face, modest movement, reinforcing hoof sterilization prevents scabies secondary infection etc.. In fact, so measure is not comprehensive enough in execution, " inducing diaphoresis " not " and in " is only played from the improvement of nutrition, therefore produce effects very Micro-, occurrence rate still occupies height, increase plant treatment difficulty and mortality the problem of sow cracked feet, causes larger loss.
The content of the invention
To solve the above problems, the present invention proposes a kind of nutrient fortified health-care type premix for preventing and treating sow cracked feet disease Material, enhance for preventing and treating sow cracked feet needed for basal nutrient, special dietary, bioactive substance include immune-regulating factor and The need for anti-inflammatory factors etc., also using Chinese herbal medicine extract, it is intended to use differential diagnosis in tcm method, sow is treated by the thought of enriching yin Internal conditioning during cracked feet, from outward appearance to inner essence fundamentally solves the problems, such as sow cracked feet.
The nutrient fortified health-care type premix of the prevention and treatment sow cracked feet disease of the present invention, every kilogram of nutrient fortified health-care Type premix is consisted of the following composition：
Bovine spinal cord protein peptone 300-350g, oat 150-200g, brown sugar 20-40g, emulsified fish oil-lard compound 100- 150g, seawood meal 10-30g, B B-complex 33.8-36.3g, are combined organic trace element 39-65g, chitosan oligosaccharide 15-25g, Fu Siberian cocklebur-the Radix Astragali-tuber of dwarf lilyturf-Rhizoma Polygonati Odorati extract 5g, surplus is fermented bean dregs.
Further, wherein the composition of the B B-complex is：Contain in every kilogram of B B-complex：Vitamin A 40.6-56.8g, vitamin D39.2-11.2g, vitamin E 88-258g, vitamin K 5.6-16.8g, vitamin B1 10.2- 21.2g, vitamin B250-105g, vitamin B618-42g, vitamin B1214.2-21.2g, nicotinic acid 102-252g, folic acid 2.8-4.2g, calcium pantothenate 48.8-84.6g, biotin 68-142g, surplus is powdered rice hulls.
Further, wherein the composition of the composite trace element is：Contain in every kilogram of composite trace element：Iodine 1.16- 1.69g, selenium 0.18-0.22g, iron 45-55g, copper 10-12g, manganese 20-25g, zinc 60-80g, methionine hydroxy calcium 450g, surplus For zeolite powder.
Further, uniformly it is mixed into the sow diets for occurring cracked feet disease by 1% adding proportion.
Preferably, the chitosan oligosaccharide molecular weight is less than 3000, the addition in every kilogram of nutrient fortified health-care type premix Measure as 20g.
Further, the Poria cocos-Radix Astragali-tuber of dwarf lilyturf-Rhizoma Polygonati Odorati extract is by tcm and herbal slice Poria cocos：The Radix Astragali：The tuber of dwarf lilyturf： Radix polygonati officinalis is by weight 1：2：2：Extracted after 1 mixing by 95% ethanol, then by the recovery ethanol that is concentrated under reduced pressure, finally will be remaining The spray drying of the Poria cocos-Radix Astragali-tuber of dwarf lilyturf-radix polygonati officinalis extract solution and obtain.
Beneficial effects of the present invention are：
1st, for the pathogenesis of sow cracked feet disease, sow itself regulative mechanism is strengthened：In the present invention, ox bone marrow have selected Peptone, emulsified fish oil-lard compound, oat, algal polysaccharides powder mainly consider its collagen egg as active material component In vain, the biological effect of linoleic acid and saturated fatty acid, pectin, mucopolysaccharide and Soluble Fiber.The pathogenesis of cracked feet disease is in fact It is that some sows fall ill, and some are not sent out in a kind of Nutrition and Metabolism disorders, same colony house, this constitution individual with sow is poor It is different relevant.Shortage of the cracked feet disease nutritionally with collagen, linoleic acid and fiber has substantial connection, simply not right in research It pays high attention to.The technical program nutriment with bioactivity sufficient by providing prevents and treats cracked feet disease.Ox Bone marrow protein peptone is ox bone marrow by enzymolysis, refined filtration, the protein raw material of low temperature spray drying, its rich in immunoglobulin, immune adjust Save peptide and various aliphatic acid, the effect with enriching blood and replenishing vital essence, to improving sow autoimmunity ability and promoting wound healing to provide Preferable basis.Contain many essential nutrient elements in ox bone marrow, wherein having to the very important Phospholipids of animal body, phosphorus Albumen etc., also prevents the ossein of organism aging process, chondroitin, the methionine for promoting liver function, each amino acid, vitamin A, B1, B2 and other trace elements.Marrow is referred to as important central immune organ, and function assessment experiment shows ox bone marrow polypeptide energy Animal body TH/TS ratios are effectively adjusted, with raising immunity function.Emulsified fish oil-lard compound, can provide easily absorption Polyunsaturated fatty acid and saturated fatty acid, during for cracked feet wound reparation provide combination fatty acid nutritive.Oat and marine alga Polysaccharide powder can not only provide the dietary fiber of high-quality, also containing pectin, mucopolysaccharide, be also the important battalion for promoting cracked feet wound healing Support and active material.Seawood meal contains substantial amounts of algal polysaccharides, can significantly improve the immunity function of sow, with the anti-mistake of anti-inflammatory It is quick, the effect of body immunity can be improved.This several raw material with special dietary characteristic and bioactivity is compounded in the production In product, the immunocompetence and wound-healing abilities of sow are fundamentally adjusted, so that the problem of solving sow cracked feet.
2nd, the incidence of hoof inflammation after cracked feet can not only be reduced, promotes the healing of sow coffin, while having to sow health Benefit：It is of the invention especially to have selected chitosan oligosaccharide, chitosan oligosaccharide be extracted from crab shell have the molecular oligosaccharides of 2-10 sugar, have This part oligosaccharides of stronger two-way immunoregulation capability, wherein glycan molecule 2-7 has stronger antiinflammatory action, is well suited for being used to send out With the sow of hoof inflammation after raw cracked feet, the generation of inflammation can be reduced, body immunity secondly can also be improved, promotes sow Health and wound-healing abilities.
3rd, Chinese medical extract replenishes qi to invigorate the spleen, and strengthens sow internal's function, so as to strengthen immunity of organisms：Poria cocos-Huang Stilbene-the tuber of dwarf lilyturf-Rhizoma Polygonati Odorati extract is a Chinese herbal compound preparation, and Poria cocos can invigorating spleen to remove dampness, enhancing body's immunity；The Radix Astragali There are invigorating qi for consolidating superficies, arrest sweating admittedly take off, torr sore myogenic, inducing diuresis for removing edema, while can also strengthen immunity of organisms；The tuber of dwarf lilyturf, radix polygonati officinalis Can nourishing Yin and moistening dryness promote the production of body fluid, can dry that to occur cracked feet more targeted for the autumn and winter with Glycerin；What the technical program was used Poria cocos-the Radix Astragali-tuber of dwarf lilyturf-Rhizoma Polygonati Odorati extract, its crude drug Poria cocos：The Radix Astragali：The tuber of dwarf lilyturf：The weight ratio of radix polygonati officinalis is 1：2：2：1, should When for sow cracked feet occurs for compound preparation, improve body self-control and play catalytic action with repair ability, and Chinese medicine is carried The nutriment that take thing has stronger bioactivity with other in this premix is mutually arranged in pairs or groups, and the reparation and prevention to cracked feet all rise Important function.
4th, the simple zinc supplementation of replacement and antibiotic therapy：The conventional zinc supplementation in pig farm and antibiotic therapy, hair is not eliminated Cause of disease because, therefore be easy to recurrence.It is with strong points using the premix of the technical program, to having occurred cracked feet disease or having had hair The sow of raw sign, specially uses the premix of the technical program in daily ration, and cracked feet symptom has clear improvement after feeding one week, Continue to feed one month or so, sow constitution is improved, and is transferred to uneasy to recur after conventinal breeding.
5th, reduce antibiotic residue in sow body, reduce the dirty harm to surrounding environment of pig farm excrement：Using this skill The nutrient fortified health-care type premix that art scheme is provided, avoids when cracked feet occurs for sow and uses antibiotic, it also avoid big The use of dosage zinc, therefore the residual of antibiotic and Zn-ef ficiency in sow body is avoided, be conducive to sow health, be also beneficial to The harmless treatment of pig manure and later-stage utilization, reduce the contamination hazard to environment.
Embodiment
Technical scheme is further illustrated below by way of specific embodiment.
Embodiment 1：
The first step：Prepare the Poria cocos-Radix Astragali-tuber of dwarf lilyturf-Rhizoma Polygonati Odorati extract：By tcm and herbal slice Poria cocos：The Radix Astragali：The tuber of dwarf lilyturf：It is beautiful Bamboo 400g by weight：800g：800g：Extracted after 400g mixing by 95% ethanol, then by the recovery ethanol that is concentrated under reduced pressure, most Remaining Poria cocos-the Radix Astragali-tuber of dwarf lilyturf-radix polygonati officinalis extract solution is spray-dried afterwards and obtained, normal temperature lucifuge kept dry is standby.
Second step：Prepare the nutrient fortified health-care type premix of prevention and treatment sow cracked feet disease, every kilogram of fortification Health premix is consisted of the following composition：
Bovine spinal cord protein peptone 350g, oat 200g, brown sugar 30g, emulsified fish oil-lard compound 100, seawood meal 20g are multiple Vitamin 36.3g is closed, organic trace element 65g is combined, chitosan oligosaccharide 20g, the Poria cocos-Radix Astragali-tuber of dwarf lilyturf-Rhizoma Polygonati Odorati extract 5g are remaining Measure as fermented bean dregs.
The composition of wherein described B B-complex is：Contain in every kilogram of B B-complex：Vitamin A 56.8g, dimension life Plain D311.2g, vitamin E2 58g, vitamin K1 6.8, vitamin B121.2g, vitamin B2105g, vitamin B642g, dimension life Plain B1221.2g, nicotinic acid 252g, folic acid 4.2g, calcium pantothenate 84.6g, biotin 142g, surplus is powdered rice hulls.
The component of wherein described composite trace element is：Calcium iodate, yeast selenium, ferrous glycine, copper methionine, methionine Manganese, zinc methionine, methionine hydroxy calcium, its content are calculated as with specific trace element：Contain in every kilogram of composite trace element：Iodine 1.69g, selenium 0.22g, iron 50g, copper 10g, manganese 20g, zinc 60g, methionine hydroxy calcium 450g, surplus is zeolite powder.
The chitosan oligosaccharide molecular weight is less than 3000.
3rd step：Cracked feet sow is selected to carry out feeding experiment
Experiment sets 2 processing, respectively control group and test group.Each 10 repetitions of processing, each repeat a sow, It is the sow that there occurs cracked feet.Control group does not make any processing, normal feeding.Test group is then in 1% ratio in its daily ration The nutrient fortified health-care type premix that the technical program is provided is added, is uniformly mixed into daily ration, is fed by normal feed mode Cracked feet sow.The feeding experiment time is 30 days, in experimental period, and test group persistently feeds 30 days nutrient fortified health-care type premixs Material.Count cure rate of the feeding experiment after 7 days and the recurrence rate after 30 days.
Treatment group Wound healing rate after 7 days Recurrence rate after 30 days
Control group 0 100%
Test group 100% 0
Result of the test is that none head of the cracked feet situation of control group is taken a turn for the better, and test group cracked feet symptom after 7 days is obtained well Reparation.Persistently feed 30 days, test group is without recurrence.Control group is not due to handling effectively, and cracked feet situation continues.
4th step：Cracked feet sow is selected to carry out further feeding experiment
Experiment sets 3 processing, respectively negative control group, positive controls and test group.Each 10 repetitions of processing, often Individual one sow of repetition, is the sow that there occurs cracked feet.Negative control group does not make any processing, without any remedy measures, just Often feeding.Positive controls use supplement zinc and antibiotic in daily ration to be treated, and test group is then in 1% ratio in its daily ration The nutrient fortified health-care type premix that the technical program is provided is added, is uniformly mixed into daily ration, is fed by normal feed mode Cracked feet sow.The feeding experiment time is 30 days, in experimental period, and test group persistently feeds 30 days nutrient fortified health-care type premixs Material, counts its cure rate after 7 days and the recurrence rate after 30 days.
Treatment group Wound healing rate after 7 days Recurrence rate after 30 days
Negative control group 0 100%
Positive controls 40% 70%
Test group 100% 0
Result above shows that cracked feet disease sow is treated in the zinc supplementation used at present using pig farm and antibiotic ruling by law, not only controls Therapeutic effect is bad, and treatment time is long, and the length generation of time one tolerance, and the method for zinc supplementation and antibiotic therapy is just less managed With sow is easy to recurrence.And the technical program is directed to the sick pathogenesis, sow constitution is adjusted from nutrition Whole, effect is more much better than zinc supplementation and effects of antibiotics.Although from the cost that single is fed, the technical program meeting is a little high, But the disorderly metabolism of cracked feet sow is adjusted normal by the health premix of the technical program, the later stage is difficult multiple Hair, in general, its cost performance are best in current various solutions.
A kind of nutrient fortified health-care type premix for preventing and treating sow cracked feet disease provided by the present invention has been carried out in detail above It is thin to introduce.The principle and embodiment of the present invention are set forth herein by embodiment, it is described above simply to use Understand the method and its core concept of the present invention in help.It should be pointed out that for those skilled in the art, Under the premise without departing from the principles of the invention, some improvement and modification can also be carried out to the present invention, these improve and modified Fall into the protection domain of the claims in the present invention.

Claims (6)

1. a kind of nutrient fortified health-care type premix for preventing and treating sow cracked feet disease, it is characterised in that every kilogram of nutrient fortified health-care Type premix is consisted of the following composition：
Fermented bean dregs 150-200g, bovine spinal cord protein peptone 300-350g, oat 150-200g, brown sugar 20-40g, emulsified fish oil-pig Oily compound 100-150g, seawood meal 10-30g, B B-complex 33.8-36.3g, are combined organic trace element 39-65g, shell Oligosaccharides 15-25g, the Poria cocos-Radix Astragali-tuber of dwarf lilyturf-Rhizoma Polygonati Odorati extract 5g, surplus is fermented bean dregs.
2. the nutrient fortified health-care type premix of sow cracked feet disease is prevented and treated according to claim 1, it is characterised in that wherein institute The composition for stating B B-complex is：Contain in every kilogram of B B-complex：Vitamin A 40.6-56.8g, vitamin D3 9.2- 11.2g, vitamin E 88-258g, vitamin K 5.6-16.8g, vitamin B110.2-21.2g, vitamin B250-105g, Vitamin B618-42g, vitamin B1214.2-21.2g, nicotinic acid 102-252g, folic acid 2.8-4.2g, calcium pantothenate 48.8- 84.6g, biotin 68-142g, surplus is powdered rice hulls.
3. the nutrient fortified health-care type premix of sow cracked feet disease is prevented and treated according to claim, it is characterised in that wherein institute The composition for stating composite trace element is：Contain in every kilogram of composite trace element：Iodine 1.16-1.69g, selenium 0.18-0.22g, iron 45-55g, copper 10-12g, manganese 20-25g, zinc 60-80g, methionine hydroxy calcium 450g, surplus is zeolite powder.
4. the nutrient fortified health-care type premix of sow cracked feet disease is prevented and treated according to claim 1, it is characterised in that by 1% Adding proportion be uniformly mixed into occur cracked feet disease sow diets in.
5. the nutrient fortified health-care type premix of sow cracked feet disease is prevented and treated according to claim 1, it is characterised in that the shell Oligosaccharide molecular amount is less than 3000, and the addition in every kilogram of nutrient fortified health-care type premix is 20g.
6. the nutrient fortified health-care type premix of sow cracked feet disease is prevented and treated according to claim 1, it is characterised in that the Fu Siberian cocklebur-the Radix Astragali-tuber of dwarf lilyturf-Rhizoma Polygonati Odorati extract is by tcm and herbal slice Poria cocos：The Radix Astragali：The tuber of dwarf lilyturf：Radix polygonati officinalis is by weight 1：2：2：1 mixes Extracted after conjunction by 95% ethanol, then by the recovery ethanol that is concentrated under reduced pressure, finally by the remaining Poria cocos-Radix Astragali-tuber of dwarf lilyturf- Radix polygonati officinalis extract solution is spray-dried and obtained.
CN201710538134.2A 2017-07-04 2017-07-04 A kind of nutrient fortified health-care type premix for preventing and treating sow cracked feet disease Pending CN107212158A (en)

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CN109924342A (en) * 2019-04-25 2019-06-25 广东广垦畜牧工程研究院有限公司 A kind of mixed feed and feed addictive and preparation method thereof for reducing sow and limb hoof disease occurring
CN111011592A (en) * 2019-12-31 2020-04-17 斯卡恩动物保健品(商丘)有限公司 Feed additive for treating sow hoof cracking and preparation and application thereof

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