CN107208131A - 用于肺癌分型的方法 - Google Patents

用于肺癌分型的方法 Download PDF

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Publication number
CN107208131A
CN107208131A CN201580039130.9A CN201580039130A CN107208131A CN 107208131 A CN107208131 A CN 107208131A CN 201580039130 A CN201580039130 A CN 201580039130A CN 107208131 A CN107208131 A CN 107208131A
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CN
China
Prior art keywords
kinds
biomarkers
grader
sample
lung cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201580039130.9A
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English (en)
Chinese (zh)
Inventor
H·法鲁基
M·莱戈德曼
C·佩罗
D·N·海耶斯
G·梅休
C·范
M·R·米格拉雷斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gene Center Therapeutics Inc
University of North Carolina at Chapel Hill
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Gene Center Therapeutics Inc
University of North Carolina at Chapel Hill
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Publication date
Application filed by Gene Center Therapeutics Inc, University of North Carolina at Chapel Hill filed Critical Gene Center Therapeutics Inc
Publication of CN107208131A publication Critical patent/CN107208131A/zh
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201580039130.9A 2014-05-30 2015-06-01 用于肺癌分型的方法 Pending CN107208131A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462005229P 2014-05-30 2014-05-30
US62/005,229 2014-05-30
PCT/US2015/033611 WO2015184461A1 (en) 2014-05-30 2015-06-01 Methods for typing of lung cancer

Publications (1)

Publication Number Publication Date
CN107208131A true CN107208131A (zh) 2017-09-26

Family

ID=54699976

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201580039130.9A Pending CN107208131A (zh) 2014-05-30 2015-06-01 用于肺癌分型的方法

Country Status (6)

Country Link
US (1) US10829819B2 (enExample)
EP (1) EP3149209B1 (enExample)
JP (1) JP2017516501A (enExample)
CN (1) CN107208131A (enExample)
CA (1) CA2950623A1 (enExample)
WO (1) WO2015184461A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112375826A (zh) * 2020-12-03 2021-02-19 远见生物科技(上海)有限公司 一种鉴别非小细胞肺癌亚型的环状rna组合物标志物及其应用

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US20190203296A1 (en) * 2015-04-14 2019-07-04 Genecentric Therapeutics, Inc. Methods for typing of lung cancer
CA3024744A1 (en) 2016-05-17 2017-11-23 Genecentric Therapeutics, Inc. Methods for subtyping of lung squamous cell carcinoma
EP3458612B1 (en) 2016-05-17 2023-11-15 Genecentric Therapeutics, Inc. Methods for subtyping of lung adenocarcinoma
EP3864165A4 (en) * 2018-10-09 2022-08-03 Genecentric Therapeutics, Inc. DETECTION OF ORIGIN CANCER CELLS
CN113186287B (zh) * 2021-05-10 2023-03-24 深圳康华君泰生物科技有限公司 用于非小细胞肺癌分型的生物标志物及其应用
CN115851927A (zh) * 2022-08-09 2023-03-28 上海善准医疗科技有限公司 肺鳞癌分子分型及生存风险基因群及诊断产品和应用

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US20100233695A1 (en) * 2007-06-01 2010-09-16 University Of North Carolina At Chapel Hill Molecular diagnosis and typing of lung cancer variants
CN101914542A (zh) * 2009-04-28 2010-12-15 中国科学院化学研究所 用于不同亚型非小细胞肺癌分型的一种核酸适体及其筛选方法
CN102099484A (zh) * 2006-05-22 2011-06-15 怡发科技股份有限公司 一种利用特定基因组合的表达特征鉴定肿瘤组织及亚型,以及用以预测患者预后与转移相关的方法
CN103764844A (zh) * 2011-03-28 2014-04-30 罗塞塔金诺米克斯有限公司 用于肺癌分类的方法

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030092009A1 (en) * 2000-11-16 2003-05-15 Kaia Palm Profiling tumor specific markers for the diagnosis and treatment of neoplastic disease
CN102099484A (zh) * 2006-05-22 2011-06-15 怡发科技股份有限公司 一种利用特定基因组合的表达特征鉴定肿瘤组织及亚型,以及用以预测患者预后与转移相关的方法
US20100233695A1 (en) * 2007-06-01 2010-09-16 University Of North Carolina At Chapel Hill Molecular diagnosis and typing of lung cancer variants
CN101914542A (zh) * 2009-04-28 2010-12-15 中国科学院化学研究所 用于不同亚型非小细胞肺癌分型的一种核酸适体及其筛选方法
CN103764844A (zh) * 2011-03-28 2014-04-30 罗塞塔金诺米克斯有限公司 用于肺癌分类的方法

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112375826A (zh) * 2020-12-03 2021-02-19 远见生物科技(上海)有限公司 一种鉴别非小细胞肺癌亚型的环状rna组合物标志物及其应用

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Publication number Publication date
EP3149209A4 (en) 2017-12-27
CA2950623A1 (en) 2015-12-03
EP3149209B1 (en) 2021-02-17
WO2015184461A1 (en) 2015-12-03
EP3149209A1 (en) 2017-04-05
US20170114416A1 (en) 2017-04-27
JP2017516501A (ja) 2017-06-22
US10829819B2 (en) 2020-11-10

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Application publication date: 20170926