CN107144568B - Sperm analysis device and analysis method thereof - Google Patents

Sperm analysis device and analysis method thereof Download PDF

Info

Publication number
CN107144568B
CN107144568B CN201710485982.1A CN201710485982A CN107144568B CN 107144568 B CN107144568 B CN 107144568B CN 201710485982 A CN201710485982 A CN 201710485982A CN 107144568 B CN107144568 B CN 107144568B
Authority
CN
China
Prior art keywords
hole
sperm
illumination
analysis device
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201710485982.1A
Other languages
Chinese (zh)
Other versions
CN107144568A (en
Inventor
尹洪兵
易清军
林仪
杨进业
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shenzhen Lepu Intelligent Medical Equipment Co ltd
Original Assignee
Shenzhen Lepu Intelligent Medical Equipment Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shenzhen Lepu Intelligent Medical Equipment Co ltd filed Critical Shenzhen Lepu Intelligent Medical Equipment Co ltd
Priority to CN201710485982.1A priority Critical patent/CN107144568B/en
Publication of CN107144568A publication Critical patent/CN107144568A/en
Application granted granted Critical
Publication of CN107144568B publication Critical patent/CN107144568B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention provides a sperm analysis device and an analysis method thereof. The sperm analysis device comprises a bearing table, a sample placement area and an optical module. The bearing table is provided with a camera shooting hole and an illumination hole, the camera shooting hole is positioned on one side of the illumination hole, and the camera shooting hole and the illumination hole are respectively aligned with a camera and a flash lamp of the same smart phone placed on the bearing table. The sample placement area is arranged below the bearing table. The optical module includes: a micro lens and a light guide assembly positioned above the sample placement area. The micro lens is arranged in the camera shooting hole or right below the camera shooting hole, the light guide component is arranged between the sample placement area and the illumination hole, and the light beam transmitted through the illumination hole is conducted to the right below the sample placement area to illuminate the sperm sample. Therefore, the sperm analysis device has simple structure and convenient operation, and is convenient for household popularization and application of the sperm analysis device.

Description

Sperm analysis device and analysis method thereof
Technical Field
The invention relates to the field of sperm activity analysis, in particular to a sperm analysis device and an analysis method thereof.
Background
At present, along with the serious pollution of living environment and the change of life style of people, the quality of human sperms is silently reduced along with mental factors. The quality of sperm is a key basis for responding male fertility, and most of detection and evaluation, such as conventional semen analysis, computer-aided sperm analysis and the like, are required to be completed by a medical institution. The medical institution can obtain a comprehensive and reliable detection result, but the medical institution has more problems such as higher examination cost, higher time cost and unsatisfactory privacy protection.
With the gradual increase of the living standard and the cultural level of people, the self health consciousness is continuously strengthened, the disease prevention and control concepts are deep into the mind of people, and how to measure the self health condition and perform rehabilitation treatment without professional staff and medical institutions is a very wide problem. The advent of home medical appliances has solved these problems, and therefore the objects of need for home medical appliances are very widespread, and the development prospect of the home medical appliance industry is very broad.
The countries release and encourage the reproduction of both fetuses, making government and childbearing age populations more concerned about reproductive health, where the quality of male sperm is an important concern; in addition, with the rapid development of science and technology, pollution of living environment is aggravated and life style of people is changed, and simultaneously, the quality of human sperm is being silently reduced along with mental factors. The data obtained from clinic shows that the infertility caused by men accounts for about 30% -40% of infertility, and 1 pair of women in every 8 pairs of women in child bearing age has the problem of difficult fertility. The quality of sperm is an important basis for responding male fertility, and most of the current tests and evaluations, such as routine semen analysis and computer-aided sperm analysis, require the patient to go to the medical institution. Although a more comprehensive and reliable detection result can be obtained in a medical institution, there are problems such as higher examination cost, higher time cost and unsatisfactory privacy protection.
The use of the current smart phones is very popular, almost all smart phones are provided with cameras and flash lamps, the processing performance of the smart phones is also high, and the smart phones can collect, analyze and store sperm images and analyze and evaluate sperm quality, so that the smart phones are used for analyzing and evaluating sperm quality at home, and the smart phones have feasibility and large actual demands.
Disclosure of Invention
The invention aims to provide a sperm analysis device and an analysis method thereof, which are based on a smart phone and can be conveniently used and operated.
A sperm analysis device comprising:
the intelligent mobile phone comprises a bearing table for bearing the intelligent mobile phone, wherein a camera hole and an illumination hole are formed in the bearing table, the camera hole is positioned on one side of the illumination hole, and the camera hole and the illumination hole are respectively aligned with a camera and a flash lamp of the same intelligent mobile phone placed on the bearing table;
the sample placement area is arranged below the bearing table and is used for placing sperm samples;
an optical module, comprising: the microscope lens is arranged in the camera hole or is arranged right below the camera hole, and the light guide component is arranged between the sample arranging region and the illumination hole and is used for transmitting a light beam transmitted through the illumination hole to the right below the sample arranging region so as to illuminate the sperm sample.
In one embodiment, the illumination hole is a long hole.
In one embodiment, the image capturing hole is a circular hole.
In one embodiment, the light guide assembly includes a reflector group, and the reflector group reflects the light beam transmitted through the illumination hole for multiple times to obtain a reflected light beam that enters the sample placement area from bottom to top.
In one embodiment, the mirror group includes: the first reflecting mirror and the second reflecting mirror form an included angle of 45 degrees with the horizontal plane, the first reflecting mirror is opposite to the reflecting surface of the second reflecting mirror, the first reflecting mirror is opposite to the illumination hole, the second reflecting mirror is opposite to the camera shooting hole and is positioned below the sample placement area, and the light beam penetrating through the illumination hole is reflected into a horizontal light beam through the first reflecting mirror and is reflected again through the second reflecting mirror, so that the light beam is vertically reflected to the sample placement area from bottom to top.
In one embodiment, the central axis of the micro lens coincides with the central axis of the light beam reflected by the second reflecting mirror.
In one embodiment, the first mirror is mounted on a movable lens mount that is capable of moving horizontally in a direction parallel to the length of the illumination aperture and/or in an up-and-down orientation away from or near the illumination aperture.
In one embodiment, the light guide assembly includes a condenser for converging the flash light beam, the condenser is located below the illumination hole, and the first reflector is located below the condenser and opposite to the condenser.
In one embodiment, the condenser is horizontally movable in a direction parallel to the length of the illumination aperture.
In one embodiment, the second reflecting mirror is fixed in position, the first reflecting mirror and the condenser are mounted on a movable arc-shaped seat, the arc-shaped seat comprises two fixing arms which are oppositely arranged, the condenser and the first reflecting mirror are respectively and fixedly arranged on the two fixing arms of the arc-shaped seat, and the arc-shaped seat can move along the length direction of the illumination hole.
In one embodiment, an adjusting rod is disposed on a side of the arcuate seat away from the second reflecting mirror, and the adjusting rod drives the arcuate seat to move.
In one embodiment, the light guide assembly includes an optical fiber, an entrance of the optical fiber is positioned below the illumination hole, and an exit of the optical fiber is positioned below the sample placement area.
In one embodiment, the entrance of the optical fiber is horizontally movable in a direction parallel to the length of the illumination hole.
In one embodiment, the light guide assembly is further provided with a condenser for converging the flash light beam, the condenser is located in the illumination hole or below the illumination hole, and the entrance of the optical fiber is located right below the condenser.
In one embodiment, the entrance of the optical fiber is mounted on a movable optical fiber fixing plate, the condenser is mounted on the condenser fixing plate, and the condenser fixing plate and the optical fiber fixing plate can move horizontally in parallel to the length direction of the illumination hole in synchronization.
In one embodiment, the sample storage device further comprises a sample bin arranged in the sample placement area, wherein the sample bin is provided with an opening for inserting a sample.
In one embodiment, the carrying platform is provided with at least two buckles, at least two buckles are oppositely arranged on the carrying platform, and the buckles are used for clamping and fixing the edges of the smart phone.
In one embodiment, the buckle is slidably disposed on the bearing table, so as to change the distance between two opposite buckles.
A method of sperm analysis comprising:
acquiring sample information by using a camera and a flash lamp of the same intelligent mobile phone;
storing and data analyzing the collected sample information on the same intelligent mobile phone to obtain an analysis result;
and storing the analysis result on the same intelligent mobile phone.
In one embodiment, the method further comprises the step of uploading the sample information and the analysis result to a server.
The sperm analysis device uses the sperm analysis method, and the light beam emitted by the flash lamp of the smart phone is conducted to the sample placement area through the light guide component, and the sperm sample is illuminated. The camera of the same smartphone above the sample placement area can take a photograph of the sperm sample through the microscope lens or record a video. Therefore, the sperm analysis device does not need to be provided with a light source, and illumination and shooting can be completed only through one smart phone. Therefore, the sperm analysis device has simple structure and convenient operation, and is convenient for household popularization and application of the sperm analysis device.
Drawings
Fig. 1 is an optical schematic diagram of a sperm analysis device according to the present embodiment.
Fig. 2 is a schematic structural view of a sperm analyzing device according to the first embodiment.
FIG. 3 is a top view of the sperm analysis device shown in FIG. 2.
Fig. 4 is a schematic structural view of a sperm analyzing device according to the second embodiment.
Fig. 5 is a schematic structural view of a sperm analyzing device according to a third embodiment.
Fig. 6 is a flowchart of the sperm analysis method according to the present embodiment.
The reference numerals are explained as follows: 10. 20, 30, sperm analysis means; 11. a carrying platform; 111. a buckle; 112. an arc surface; 113. 213, 313, an imaging aperture; 114. 214, 314, illumination apertures; 12. 221, 32, sample placement area; 13. an optical module; 131. 231, 331, a microscope lens; 132. 232, 332, a light guide assembly; 133. 233, a first mirror; 333. an optical fiber; 134. 234, a second mirror; 334. an optical fiber fixing plate; 135. 235, 335, a condenser; 236. 336, condenser fixing plate; 137. 237, fixing holes; 14. 24, a housing; 15. 25, a sample bin; 16. an arcuate seat; 161. a fixed arm; 162. an adjusting rod; 163. a connecting arm; 26. a lens holder; 2. a smart phone; 21. a camera; 22. a flash lamp; 3. sperm samples.
Detailed Description
Exemplary embodiments that embody features and advantages of the present invention will be described in detail in the following description. It will be understood that the invention is capable of various modifications in various embodiments, all without departing from the scope of the invention, and that the description and illustrations herein are intended to be by way of illustration only and not to be construed as limiting the invention.
Referring to fig. 1 and 2, the present invention provides a sperm analyzing apparatus 10. The sperm analysis device 10 comprises a carrying platform 11 for carrying the smartphone 2, a sample placement zone 12 and an optical module 13.
The carrying platform 11 is a working platform. The carrying platform 11 may be a surface platform of a frame structure or a surface of a box structure made of a plate material. And, the surface area of the carrying floor 11 is larger than the surface area of the smartphone 2. Therefore, the smart phone 2 can be placed on the carrying platform 11 horizontally or vertically according to the use requirement.
In particular, in the present embodiment, at least two clips 111 are provided on the carrying platform 11. At least two buckles 111 are relatively arranged on the bearing table 11, and the buckles 111 are used for clamping and fixing the edge of the smart phone 2. Specifically, the number of the fasteners 111 may be four, and the four fasteners 111 are rectangular and distributed on the carrying platform 11 to define an accommodating space. The smart phone 2 is placed in the accommodating space, and each buckle 111 corresponds to one side of the smart phone 2. When the smart phone 2 is placed and positioned, the four buckles 111 are respectively engaged and fixed corresponding to one side edge of the smart phone 2, so as to prevent the smart phone 2 from moving on the bearing table 11 and affecting the use of the sperm analysis device 10.
Also, as shown in FIG. 2, sperm analysis device 10 further includes a housing 14. The clasp 111 may also be provided on the housing 14 of the sperm analysis device 10. The side of the buckle 111 facing the accommodating space is an arc-shaped surface 112. The arc-shaped surface 112 can be matched with the smooth edge of the smart phone 2, so that the buckle 111 and the smart phone 2 can be stably abutted.
Because the sizes and types of the smartphones 2 are different, the bearing table 11 is suitable for the fixed requirements of various smartphones 2. Thus, the buckle 111 can be slidably disposed on the carrying platform 11 to change the distance between two oppositely disposed buckles 111. The buckle 111 can also realize the adjustment of the position of the buckle 111 through a sliding rail and a fastening bolt. When the buckle 111 moves to a proper position along the slide rail, the fastening bolt fixes the buckle 111 on the slide rail, so that the buckle 111 is fixed, and the smart phone 2 is fixed.
In other embodiments, the buckle 111 may also be telescopically connected to the carrying platform 11 by a telescopic arm, a spring or the like. The connection manner of the buckle 111 and the carrying platform 11 is not particularly limited, as long as the distance between two opposite buckles 111 can be changed, so as to achieve the purpose of fixing the smart phone 2 with various sizes.
The carrying table 11 is provided with an imaging hole 113 and an illumination hole 114. The camera hole 113 is located at one side of the illumination hole 114, and the camera hole 113 and the illumination hole 114 are aligned with the camera 21 and the flash 22 of the same smartphone 2 placed on the carrying table 11, respectively. Specifically, in the present embodiment, the camera 21 is aligned with the image pickup hole 113, and the flash 22 is aligned with the illumination hole 114. Referring to fig. 3, and in particular, the illumination hole 114 is a long hole. The imaging hole 113 is a circular hole. Through the runway-shaped illumination hole 114, when the flash lamp 22 of the smart phone 2 is located at different positions along the length direction of the illumination hole 114, the flash lamp 22 of the smart phone 2 is located at different positions of the long hole, so that the carrying table 11 is matched with the situation that distances between the cameras 21 and the flash lamps 22 of different smart phones 2 are different.
A sample placement area 12 is provided below the carrier 11 for placement of the sperm sample 3. The sample placement area 12 is provided on the other side of the carrying floor 11 with respect to the smartphone 2. In particular, in this embodiment, sperm analysis device 10 further comprises a sample compartment 15 disposed within sample placement region 12. The sample compartment 15 is provided with an opening into which the sperm sample 3 is inserted. Sperm sample 3 is placed in sample placement region 12 by sample chamber 15. A support arm or table is provided on the inside wall of the housing 14 to support the sample compartment 15 secured within the sample receiving area 12. The sample compartment 15 is a transparent box-like structure. The sample bin 15 is provided with only one opening for the sperm sample 3 to enter and exit, and other sides are all sealing surfaces. On the one hand, the sample bin 15 can protect the sperm sample 3 from contamination; on the other hand, the sample bin 15 can prevent the sperm sample 3 from overflowing during analysis, and avoid contaminating the sperm analysis device 10.
In other embodiments, sperm sample 3 may be placed directly onto sample placement region 12 by a support arm or table. Also, the sample chamber 15 may have a box-like structure with transparent sides on only the upper and lower sides. The structural content of the sample chamber 15 is not limited herein.
Referring to fig. 2, the optical module 13 includes a micro lens 131 and a light guide 132 above the sample placement area 12.
The microlens 131 is provided in the image pickup hole 113 or directly below the image pickup hole 113. The micro lens 131 is disposed opposite to the image pickup hole 113, and the micro lens 131 enables the camera 21 of the smartphone 2 to image sperm, blood cells, and the like. Specifically, the micro lens 131 is a micro lens.
The light guide 132 is disposed between the sample placement area 12 and the illumination aperture 114, and guides the light beam transmitted through the illumination aperture 114 to the position directly below the sample placement area 12 to illuminate the sperm sample 3.
The sperm analyzing device 10 conducts the light beam emitted from the flash 22 of the smart phone 2 to the sample placement area 12 through the light guide assembly 132, and illuminates the sperm sample 3. The camera 21 of the same smartphone 2 located above the sample placement zone 12 is able to take a picture or record video of the sperm sample 3 through the microlens 131. Therefore, the sperm analyzing device 10 can complete illumination and photographing by only one smart phone 2 without providing a light source. Therefore, the sperm analyzing device 10 has simple structure and convenient operation, and is convenient for the household popularization and application of the sperm analyzing device 10.
In particular, in this embodiment, the light guide assembly 132 includes a mirror group. The mirror group reflects the light beam transmitted through the illumination hole 114 a plurality of times to obtain a reflected light beam that enters the sample placement area 12 from bottom to top. The mirror group is designed to reflect the light beam from the light beam transmitted through the illumination hole 114 to the sample placement area 12 according to the optical path design requirement.
Specifically, the mirror group includes a first mirror 133 and a second mirror 134. The included angles between the first reflecting mirror 133 and the second reflecting mirror 134 and the horizontal plane are 45 degrees, and the reflecting surfaces of the first reflecting mirror 133 and the second reflecting mirror 134 are opposite. The first reflecting mirror 133 is opposite to the illumination hole 114, and the second reflecting mirror 134 is opposite to the image pickup hole 113 and is located below the sample placement area 12. The light beam transmitted through the illumination hole 114 is reflected by the first mirror 133 into a horizontal light beam, and then reflected by the second mirror 134 for a second time, so that the light beam is reflected vertically from bottom to top to the sample placement area 12. The light beam transmitted through the illumination hole 14 is reflected by the first mirror 133 and the second mirror 134, changing the propagation direction of the light beam by 180 degrees. Therefore, the camera 21 of the smartphone 2 can utilize the light beam of the flash 22. And the light beam can be vertically reflected onto the sperm sample 3 from bottom to top, so that the light beam can be uniformly projected onto the sperm sample 3, and the camera can be ensured to clearly image.
Specifically, the length of the first mirror 133 needs to be more than 1.414 times the length of the illumination aperture 114. That is, the light beam transmitted through the illumination hole 114 can be entirely projected onto the first reflecting mirror 133, and the utilization ratio of the light beam is ensured.
Also, the light guide assembly 132 includes a condenser 135 for condensing the light beam of the flash 22. The condenser 135 is located in the illumination aperture 114 or below the illumination aperture 114. In particular, in this embodiment, the condenser 135 is located below the illumination aperture 114. The condenser 135 is used to collect the light beam of the flash 22 transmitted through the illumination aperture 114. Since the light emitted from the flash 22 of the smart phone 2 is a divergent light beam, the divergent light beam is changed into a parallel light beam by using the condenser 135, and the light beam transmitted through the illumination hole 114 is more uniform and has a larger intensity.
The first reflecting mirror 133 is disposed below the condenser 135 and opposite to the condenser 135. When the flash 22 of the smart phone 2 is located at different positions along the length direction of the illumination hole 114, the corresponding condenser 135 and the first mirror 133 can also move horizontally along the length direction parallel to the illumination hole 114, so that the relative positions among the flash 22, the condenser 135 and the first mirror 133 are kept stable.
In the first embodiment, the position of the second mirror 134 is fixed. The second reflecting mirror 134 is fixedly disposed on the bottom surface of the housing 14. One end of the second reflecting mirror 134 is at an angle of 45 degrees to the bottom surface of the housing 14, and the other end is also at an angle of 45 degrees to the side of the housing 14. And, the central axis of the micro lens 131 coincides with the central axis of the light beam reflected by the second reflecting mirror 134.
The first mirror 133 and the condenser 135 are mounted on a movable arcuate mount 16. An arcuate seat 16 is slidably mounted on the bottom surface of the housing 14.
The arcuate seat 16 includes two oppositely disposed fixed arms 161 and a connecting arm 163 perpendicular to the two fixed arms 161. The condenser 135 and the first reflecting mirror 133 are respectively fixed on two fixing arms 161 of the arcuate base 16. The condenser 135 is mounted on the fixed arm 161 at the top end of the arcuate arm 16, and the first mirror 133 is mounted on the fixed arm 161 at the bottom end of the arcuate arm 16. One end of the first mirror 133 is at a 45 degree angle to the bottom surface of the housing 14 and the other end is also at a 45 degree angle to the connecting arm 163 of the arcuate arm 16. In addition, the central axis of the condenser 135 passes through the center point of the first mirror 133, and the central axis is parallel to the side of the arcuate arm 16 remote from the second mirror 134.
Also, the arcuate seat 16 is movable along the length of the illumination aperture 114. The side of the arcuate seat 16 remote from the second mirror 134 is provided with an adjustment lever 162, i.e. the side of the connecting arm 163 remote from the second mirror 134 is provided with an adjustment lever 162. The adjusting lever 162 moves the arcuate seat 16. An operator can move arcuate arm 16 along the length of illumination aperture 114 by pushing and pulling adjustment lever 162, stopping adjustment when adjustment is made to the point where condenser 135 is in alignment with flashlight 22 of smartphone 2.
Also, in the first embodiment, the condenser 135 may be omitted. The fixing arm 161 to which the condenser 135 is attached is provided with a fixing hole 137 for accommodating the condenser 135. The fixing hole 137 is a circular through hole, so that the light beam passing through the illumination hole 114 can reach the first reflecting mirror 133 when passing through the fixing hole 137. The superfluous light beam is prevented from being projected to a place outside the first reflecting mirror 133 and enters the sperm analysis device 10, so that the imaging of the sperm analysis device 10 is prevented from being influenced.
Referring to fig. 4, in the sperm analyzing device 20 of the second embodiment, the light guiding component 232 includes a first mirror 233 and a second mirror 234. Wherein the second mirror 234 is fixed in position, and the second mirror 234 is fixedly disposed on the bottom surface of the housing 24. One end of the second mirror 234 is at a 45 degree angle to the bottom surface of the housing 24 and the other end is also at a 45 degree angle to the side of the housing 24. And, the central axis of the micro lens 231 coincides with the central axis of the light beam reflected by the second reflecting mirror 234.
The first mirror 233 is mounted on a movable lens mount 26. The lens holder 26 can be moved horizontally in a direction parallel to the length of the illumination aperture 214 and/or in an up-and-down orientation away from or near the illumination aperture 214. In other embodiments, the position of the second mirror 234 may not be fixed. The second mirror 234 moves up and down simultaneously with the first mirror 233, and the effect of vertically reflecting the light beam from bottom to top to the sample mounting region 221 can be achieved.
When the flash 22 of the smart phone 2 is located at different positions along the length direction of the illumination hole 214, the light collector 235 is fixedly disposed on the light collector fixing plate 236, and the light collector fixing plate 236 is correspondingly adjusted to align the light collector 235 with the flash 22, so that the incident point of the light beam transmitted through the illumination hole 214 and incident on the first reflecting mirror 233 is changed. In order to ensure that the central axis of the beam reflected by the second mirror 234 coincides with the central axis of the micro lens 231, the first mirror 233 needs to be moved horizontally or up and down. Thus, the reflected light beam can be vertically reflected from bottom to top to the sample mounting region 221, and symmetry of the reflected light beam with respect to the central axis of the microlens 231 is ensured. The beam can be reflected vertically from bottom to top onto the sperm sample 3 within the sample chamber 25. The reflected light beam is symmetrical about the central axis of the micro lens 231 in the camera hole 213, so that the light entering the micro lens 231 is sufficient, and the camera 21 of the smart phone 2 can clearly image.
Also, in the second embodiment, the condenser 235 may be omitted. The fixing hole 237 for accommodating the condenser 235 is formed in the condenser fixing plate 236, and the fixing hole 237 is a circular through hole, so that the light beam passing through the illumination hole 214 can reach the first reflecting mirror 233 when passing through the fixing hole 237. The superfluous light beam is prevented from being projected to a place outside the first reflecting mirror 233 and enters the sperm analysis device 20, so that the imaging of the sperm analysis device 20 is prevented from being influenced.
Referring to fig. 5, in the sperm analyzing device 30 of the third embodiment, the light guide assembly 332 includes an optical fiber 333. The entrance of the fiber 333 is located below the illumination aperture 314. The exit port of the optical fiber 333 is located below the sample placement area 32. Correspondingly, the microscope 331 is mounted in the image pickup hole 313. The entrance of the optical fiber 333 is provided directly below the condenser 335. The entrance of the optical fiber 333 is mounted on a movable optical fiber fixing plate 334, and the condenser 335 is mounted on a condenser fixing plate 336. The condenser fixing plate 336 and the optical fiber fixing plate 334 can be horizontally moved in parallel to the length direction of the illumination hole 314 in synchronization. When the condenser 335 is horizontally moved in a direction parallel to the length of the illumination hole 314, the entrance of the optical fiber 333 can be horizontally moved in a direction parallel to the length of the illumination hole 314.
When the flash 22 of the smart phone 2 is located at different positions in the illumination hole 314, the corresponding light collector 335 and the entrance of the optical fiber 333 can horizontally move along the direction parallel to the length direction of the illumination hole 314, so that the relative positions among the flash 22, the light collector 335 and the entrance of the optical fiber 333 are kept stable.
In other embodiments, when the carrying platform 11 is designed for a specific type of smartphone 2, the distance between the camera 21 of the smartphone 2 and the flash 22 is a fixed value, and the flash 22 is located at a fixed position of the illumination hole 114, so the position of the condenser 135 does not need to be moved. Therefore, the condenser 135 can be directly fixed in the illumination hole 114, and the function of converging the light beam of the flash lamp 22 can be realized, so that the purpose of providing illumination for the sperm analysis device 10 can be achieved.
The invention also provides a sperm analysis method.
Referring to fig. 6, a sperm analysis method includes:
and S11, acquiring sample information by using a camera and a flash lamp of the same smart phone.
And step S12, storing and data analyzing the collected sample information on the same intelligent mobile phone to obtain an analysis result.
The method integrates an algorithm and an operation interface for analyzing sperm quality on the smart phone, and the smart phone can be used for directly calculating an analysis result based on the shot image and video and directly presenting the analysis result to a user.
And step S13, storing the analysis result on the same intelligent mobile phone.
The sperm analysis method can also store the acquired sample information, analysis results and processes in a memory card of the smart phone, and archive the data.
The sperm analysis method of the present embodiment further includes a step of uploading the sample information and the analysis result to a server.
In the step, the server is connected through a wireless network under the condition of network connection, and the sample information acquired in the testing process and the analysis result obtained by data analysis are synchronously stored in the server.
In the sperm analysis method of the present embodiment, sample information of image and video data acquired by a user and an analysis result are uploaded to a server in synchronization during the design of an application program. For each detection, the storage space of the smart phone can be saved, about 100 Mbytes of data. When the user places the smart phone in an environment with wireless network connection, the application software can upload sample information and analysis results acquired earlier to the server. Specifically, the latest three sample information and analysis results are reserved so as not to occupy more storage space of the smart phone. And uploading the sample information and the analysis result to a server and encrypting and storing, wherein the sample information and the analysis result correspond to the user of the intelligent mobile phone. If the smart phone user needs to check the earlier sample information and analysis result, the smart phone user can download and check the sample information and analysis result through a wireless network in an environment with wireless network connection.
While the invention has been described with reference to several exemplary embodiments, it is to be understood that the terminology used is intended to be in the nature of words of description and of limitation. As the present invention may be embodied in several forms without departing from the spirit or essential characteristics thereof, it should also be understood that the above-described embodiments are not limited by any of the details of the foregoing description, but rather should be construed broadly within its spirit and scope as defined in the appended claims, and therefore all changes and modifications that fall within the meets and bounds of the claims, or equivalences of such meets and bounds are therefore intended to be embraced by the appended claims.

Claims (15)

1. A sperm analysis device comprising:
the intelligent mobile phone comprises a bearing table for bearing the intelligent mobile phone, wherein a camera hole and an illumination hole are formed in the bearing table, the camera hole is positioned on one side of the illumination hole, and the camera hole and the illumination hole are respectively aligned with a camera and a flash lamp of the same intelligent mobile phone placed on the bearing table;
the sample placement area is arranged below the bearing table and is used for placing sperm samples;
an optical module, comprising: the microscope lens is arranged in the camera hole or is arranged right below the camera hole, and the light guide component is arranged between the sample arranging region and the illumination hole and is used for transmitting a light beam transmitted through the illumination hole to the right below the sample arranging region so as to illuminate a sperm sample;
the light guide assembly comprises a reflector group, wherein the reflector group reflects the light beam transmitted through the illumination hole for multiple times and reflects the light beam to the sample placement area from bottom to top;
the mirror group includes: the first reflecting mirror and the second reflecting mirror form an included angle of 45 degrees with the horizontal plane, the first reflecting mirror is opposite to the reflecting surface of the second reflecting mirror, the first reflecting mirror is opposite to the illumination hole, the second reflecting mirror is opposite to the camera shooting hole and is positioned below the sample placement area, and the light beam penetrating through the illumination hole is reflected into a horizontal light beam through the first reflecting mirror and is reflected again through the second reflecting mirror, so that the light beam is vertically reflected to the sample placement area from bottom to top;
the first mirror is mounted on a movable lens mount that is capable of moving horizontally in a direction parallel to the length of the illumination aperture and/or in an up-and-down orientation away from or near the illumination aperture.
2. The sperm analysis device as claimed in claim 1, wherein said illumination aperture is a slot.
3. The sperm analysis device as set forth in claim 1, wherein said camera aperture is a circular aperture.
4. The sperm analysis device as set forth in claim 1, wherein a central axis of said microscope lens coincides with a central axis of a light beam reflected by said second mirror.
5. The sperm analysis device as set forth in claim 1 wherein said light guide assembly includes a condenser for converging said flash light beam, said condenser being positioned below said illumination aperture, said first mirror being positioned below and opposite said condenser.
6. The sperm analysis device as claimed in claim 5, wherein said light collector is horizontally movable in a direction parallel to a length of said illumination aperture.
7. The sperm cell as described in claim 6, wherein said second mirror is fixed in position, said first mirror and said condenser are mounted on a movable arcuate mount, said arcuate mount comprising two oppositely disposed fixed arms, said condenser and said first mirror being fixedly disposed on said arcuate mount's two fixed arms, respectively, said arcuate mount being movable along the length of said illumination aperture.
8. The sperm analysis device as claimed in claim 7, wherein an adjustment lever is provided on a side of said arcuate seat remote from said second mirror, said adjustment lever moving said arcuate seat.
9. The sperm analysis device as claimed in claim 1, wherein said light guide assembly comprises an optical fiber, an entrance port of said optical fiber being positioned below said illumination aperture, and an exit port of said optical fiber being positioned below said sample placement region.
10. The sperm analysis device as claimed in claim 9, wherein said entrance port of said optical fiber is horizontally movable in a direction parallel to a length of said illumination aperture.
11. The sperm analysis device as claimed in claim 9, wherein a condenser for converging the flash light beam is further provided on the light guide assembly, the condenser is located in or below the illumination aperture, and the entrance port of the optical fiber is located directly below the condenser.
12. The sperm analysis device as claimed in claim 11, wherein said entrance port of said optical fiber is mounted on a movable optical fiber mounting plate, said optical concentrator is mounted on said optical concentrator mounting plate, and said optical concentrator mounting plate and said optical fiber mounting plate are capable of being moved horizontally in a direction parallel to the length of said illumination aperture in synchronization therewith.
13. The sperm analysis device as claimed in claim 1, further comprising a sample compartment disposed in the sample placement region, the sample compartment being provided with an opening for insertion of a sample.
14. The sperm analysis device as claimed in claim 1, wherein said carrier is provided with at least two clasps, at least two clasps are disposed on said carrier, said clasps are used for clamping and fixing edges of said smart phone.
15. The sperm analysis device as claimed in claim 14, wherein said clasp is slidably disposed on said carrier to vary a distance between two oppositely disposed clasps.
CN201710485982.1A 2017-06-23 2017-06-23 Sperm analysis device and analysis method thereof Active CN107144568B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710485982.1A CN107144568B (en) 2017-06-23 2017-06-23 Sperm analysis device and analysis method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710485982.1A CN107144568B (en) 2017-06-23 2017-06-23 Sperm analysis device and analysis method thereof

Publications (2)

Publication Number Publication Date
CN107144568A CN107144568A (en) 2017-09-08
CN107144568B true CN107144568B (en) 2023-06-20

Family

ID=59782082

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201710485982.1A Active CN107144568B (en) 2017-06-23 2017-06-23 Sperm analysis device and analysis method thereof

Country Status (1)

Country Link
CN (1) CN107144568B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK179445B1 (en) * 2017-09-08 2018-10-09 Exseed Health Aps Device for testing a biological sample
CN109655451A (en) * 2017-10-10 2019-04-19 中山大学 A kind of portable colour comparison detection apparatus
KR102210306B1 (en) * 2018-08-28 2021-02-09 (주)인트인 Test Apparatus for Analysing Body Fluid
CN111158134B (en) * 2020-01-09 2021-09-10 江苏大学 Microscope device based on any type of portable smart phone and using method

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103983572A (en) * 2014-05-12 2014-08-13 杨征 Optical detection and diagnostic device on basis of mobile equipment
CN104921699A (en) * 2015-06-18 2015-09-23 苏州四海通仪器有限公司 Ophthalmoscope based on mobile intelligent terminal
CN204679425U (en) * 2015-04-23 2015-09-30 广州博厚医疗技术有限公司 Handheld analysis
CN205317794U (en) * 2015-12-29 2016-06-15 中国科学院苏州生物医学工程技术研究所 Reflective micropore board formation of image mechanism with tray is gone into to pop out by bullet
CN106769947A (en) * 2017-01-26 2017-05-31 夏明亮 The auxiliary acquisition device and absorbency detection method of testing sample image
CN206906258U (en) * 2017-06-23 2018-01-19 深圳乐普智能医疗器械有限公司 sperm analysis device

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2896082A1 (en) * 2012-12-21 2014-06-26 Joel R. L. Ehrenkranz Supplements and monitoring systems for dosing of the supplements

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103983572A (en) * 2014-05-12 2014-08-13 杨征 Optical detection and diagnostic device on basis of mobile equipment
CN204679425U (en) * 2015-04-23 2015-09-30 广州博厚医疗技术有限公司 Handheld analysis
CN104921699A (en) * 2015-06-18 2015-09-23 苏州四海通仪器有限公司 Ophthalmoscope based on mobile intelligent terminal
CN205317794U (en) * 2015-12-29 2016-06-15 中国科学院苏州生物医学工程技术研究所 Reflective micropore board formation of image mechanism with tray is gone into to pop out by bullet
CN106769947A (en) * 2017-01-26 2017-05-31 夏明亮 The auxiliary acquisition device and absorbency detection method of testing sample image
CN206906258U (en) * 2017-06-23 2018-01-19 深圳乐普智能医疗器械有限公司 sperm analysis device

Also Published As

Publication number Publication date
CN107144568A (en) 2017-09-08

Similar Documents

Publication Publication Date Title
CN107144568B (en) Sperm analysis device and analysis method thereof
KR102179088B1 (en) Home testing device
TWI647452B (en) Testing equipment with magnifying function
WO2015164322A1 (en) Assay detector device compatible with any handheld digital camera/portable computing device
KR20200041995A (en) A universal rapid diagnostic test reader with trans-visual sensitivity
JP6514832B2 (en) Observation device
TW201617680A (en) Testing equipment with magnifying function
CN105011898A (en) Self-service type infrared eccentric photorefractor and self-service photorefraction method
CN111579466B (en) Household sperm detection device and detection method
CN104807822A (en) Handheld analyzer and detection method
JP2021535373A (en) Image of surface color and liquid contact angle
CN206906258U (en) sperm analysis device
JP2014211322A (en) Optical characteristic measurement device
CN210181293U (en) Microscope device capable of automatically focusing
CN104154991B (en) A kind of illuminance measuring method for testing and this illuminance measuring electricity testing device
CN112919124A (en) Sample information identification device and method
CN219435111U (en) Light path structure of portable sperm quality analyzer
CN112153364A (en) Stray light detection apparatus and method
CN219871029U (en) Portable sperm quality analyzer
CN112945956B (en) Slide loading detection method and device, terminal equipment and storage medium
CN219914822U (en) Safety test system of optical module
CN112230493B (en) Mobile phone microscopic magnification shooting device
KR20220064075A (en) Small studio device for photographing the plate from the top
CN116008265A (en) Portable sperm quality analysis method and system
US20240156443A1 (en) Tissue cassette reader

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant