CN107126401A - A kind of attapulgite clay talcum powder and preparation method thereof - Google Patents
A kind of attapulgite clay talcum powder and preparation method thereof Download PDFInfo
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- CN107126401A CN107126401A CN201710360556.5A CN201710360556A CN107126401A CN 107126401 A CN107126401 A CN 107126401A CN 201710360556 A CN201710360556 A CN 201710360556A CN 107126401 A CN107126401 A CN 107126401A
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- talcum powder
- attapulgite clay
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/26—Aluminium; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/30—Zinc; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/904—Stemonaceae (Stemona family), e.g. croomia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0241—Containing particulates characterized by their shape and/or structure
- A61K8/0279—Porous; Hollow
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/27—Zinc; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q15/00—Anti-perspirants or body deodorants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/56—Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms
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Abstract
The invention discloses a kind of attapulgite clay talcum powder and preparation method thereof, the raw materials such as attapulgite clay powder, calamine, folium artemisiae argyi, rhizoma atractylodis, the fruit of summer cypress, the tuber of stemona, ethylene bis stearamide are added in ball mill after wet ball grinding and dried, grind again, obtain attapulgite clay talcum powder.Attapulgite clay talcum powder prepared by the present invention has good slipping and ability of sweat absorption, and stops miliaria and antipruritic function with persistence.
Description
Technical field
The present invention relates to a kind of attapulgite clay talcum powder and preparation method thereof, belong to skin care field.
Background technology
Prickly heat is a kind of summer common skin acute inflammation, is mostly occurred at positions, child such as neck, thoracic dorsal, fossa cubitalis, popliteal nests
Can occur on head, forehead etc..From the beginning of when rubefaction, then there is pinhead-sized red papules or papulo-vesicle, it is intensive
In flakes, some of which papule is in purulence.Itching after prickly heat, pain have been given birth to, the performance such as a burst of hot cusalgia is also had sometimes.
Talcum powder has absorbing sweat dehumidifying, the only antipruritic function of miliaria, but talcum powder on the market generally contains talcum powder and otherization at present
Additive is learned, there is certain excitant to human body skin.It is raw material that traditional talcum powder, which is mainly talcum powder, is commercially also taken up
Leading position, is main product, and such a talcum powder is cheap, it is easy to promote.The main component of talcum powder is magnesium silicate, due to
Its six unique side flat crystal structure is with good lubricity, and its addition in talcum powder is at a relatively high.Talcum
Powder be by natural crystal crush form, its natural impurity be asbestos, asbestos be it is a kind of can with carcinogenic material, seriously endanger human body
It is healthy.
Attapulgite clay powder has special microfibre structure and special nanometer porous road fine structure, determines it
With very strong adsorptivity：Most cation, hydrone and a certain size organic molecule can be directly adsorbed into it
In fine duct.Using attapulgite clay powder, calamine, folium artemisiae argyi, rhizoma atractylodis, the fruit of summer cypress, the tuber of stemona, niacinamide, ethylene stearic bicine diester
The research that amine prepares attapulgite clay talcum powder for raw material and using wet ball grinding technique has not yet to see report.The master of calamine
Composition is wanted for zinc carbonate, and calcium containing small amounts, magnesia, iron oxide, manganese oxide etc., it has treatment scytitis and surface
The function of wound.Folium artemisiae argyi is a kind of Chinese medicine for having and treating pruitus function.Rhizoma atractylodis are a kind of with wind-dispelling and dehumidifying functions
Chinese medicine.The fruit of summer cypress is a kind of Chinese medicine with antipruritic function.The tuber of stemona is a kind of Chinese medicine with the antipruritic function of desinsection.The change of nicotinoyl
Product are a kind of derivatives of vitamin B3, are also the generally acknowledged skin anti-aging composition in cosmetic dermatology field, can mitigate and
The colour of skin that prevention skin is produced in early stage aging course is dull and turns to be yellow, and can also repair impaired Stratum corneum lipids barrier,
Improve skin resistance.Ethylene bis stearamide is nontoxic, human body is had no side effect and with excellent lubricity, can industrially be done
Lubricating type additive is used.
The content of the invention
It is an object of the invention to provide a kind of attapulgite clay talcum powder and preparation method thereof, prepared using this method
Attapulgite clay talcum powder has good only miliaria, antipruritic and ability of sweat absorption.
To achieve the above objectives, the present invention, which is adopted the following technical scheme that, is achieved：
A kind of method for preparing above-mentioned attapulgite clay talcum powder, it is characterised in that this method comprises the following steps：
Step 1: in mass ratio, weighing the raw material of following components：Attapulgite clay powder: calamine: folium artemisiae argyi: rhizoma atractylodis: the fruit of summer cypress:
The tuber of stemona: niacinamide: ethylene bis stearamide: ethanol=100:（1~4）∶（1~3）∶（1~4）∶（1~4）∶（1~3）∶（1~5）
∶（1~6）∶（100~150）；Raw material after above-mentioned weighing is added into wet grinding 1~2 hour in ball mill, pastel is obtained；
Step 2: the pastel drying that step one is obtained is then added to dry grinding in ball mill after removing ethanol, obtain recessed
Convex rod clay talcum powder.
The present invention has advantages below compared with prior art：
（1）When the present invention prepares attapulgite clay talcum powder, using calamine, folium artemisiae argyi, rhizoma atractylodis, the fruit of summer cypress, the tuber of stemona this it is several in
Medicine and niacinamide are re-dubbed compound formulation, obtained attapulgite clay talcum powder is had good only miliaria and antipruritic function；
（2）When the present invention prepares attapulgite clay talcum powder, using attapulgite clay powder because of its special microfibre structure and
Special nanometer porous road fine structure and the good absorption property having, to adsorb calamine, folium artemisiae argyi, rhizoma atractylodis, summer cypress
Son, effective medicinal ingredient in the tuber of stemona and niacinamide are simultaneously sustained, and obtained attapulgite clay talcum powder is had well lasting
Property stops miliaria, antipruritic and skin repair function；
（3）When the present invention prepares attapulgite clay talcum powder, using attapulgite clay powder because of its special microfibre structure and
Special nanometer porous road fine structure and the good absorption property having, have obtained attapulgite clay talcum powder
Good ability of sweat absorption；
（4）When the present invention prepares attapulgite clay talcum powder, ethanol wet ball grinding is added in the feed, is dissolved and leached using ethanol
Effective medicinal ingredient in calamine, folium artemisiae argyi, rhizoma atractylodis, the fruit of summer cypress, the tuber of stemona, makes these effective medicinal ingredients well by concave convex rod
Clay powder is adsorbed and is sustained, so that the only antipruritic function of miliaria of obtained attapulgite clay talcum powder has good persistence；
（5）When the present invention prepares attapulgite clay talcum powder, make obtained concave convex rod using the ethylene bis stearamide in raw material
Clay talcum powder have good slipping.
Embodiment
Below by specific embodiment, technical scheme is described in further detail.
Embodiment 1
The preparation method of the attapulgite clay talcum powder of the present embodiment comprises the following steps：
Step 1: in mass ratio, weighing the raw material of following components：Attapulgite clay powder: calamine: folium artemisiae argyi: rhizoma atractylodis: the fruit of summer cypress:
The tuber of stemona: niacinamide: ethylene bis stearamide: ethanol=100: 2: 2: 3: 2: 2: 3: 4: 125；Raw material after above-mentioned weighing is added
Wet grinding 1.5 hours, obtain pastel in ball mill；
Step 2: the pastel drying that step one is obtained is then added to dry grinding in ball mill after removing ethanol, obtain recessed
Convex rod clay talcum powder.
Embodiment 2
The preparation method of the attapulgite clay talcum powder of the present embodiment comprises the following steps：
Step 1: in mass ratio, weighing the raw material of following components：Attapulgite clay powder: calamine: folium artemisiae argyi: rhizoma atractylodis: the fruit of summer cypress:
The tuber of stemona: niacinamide: ethylene bis stearamide: ethanol=100: 4: 3: 3: 1: 3: 5: 6: 150；Raw material after above-mentioned weighing is added
Wet grinding 2 hours, obtain pastel in ball mill；
Step 2: the pastel drying that step one is obtained is then added to dry grinding in ball mill after removing ethanol, obtain recessed
Convex rod clay talcum powder.
Embodiment 3
The preparation method of the attapulgite clay talcum powder of the present embodiment comprises the following steps：
Step 1: in mass ratio, weighing the raw material of following components：Attapulgite clay powder: calamine: folium artemisiae argyi: rhizoma atractylodis: the fruit of summer cypress:
The tuber of stemona: niacinamide: ethylene bis stearamide: ethanol=100: 1: 1: 1: 4: 1: 1: 1: 100；Raw material after above-mentioned weighing is added
Wet grinding 1 hour, obtains pastel in ball mill；
Step 2: the pastel drying that step one is obtained is then added to dry grinding in ball mill after removing ethanol, obtain recessed
Convex rod clay talcum powder.
Experimental example：
1st, Zou, female, 8 years old, there was intensive sheet of prickly heat at patient back, and itch is obvious, the course of disease 2 days.Prepared using embodiment 1
Powder is applied outside, and itch mitigates, and second day prickly heat diminishes, after the 3rd day, and prickly heat disappears.
2nd, Mr. Wang, male, 9 years old, patient saw at back sheet of prickly heat, and red and swollen, itch is obvious, the course of disease 3 days.Use embodiment 2
The attapulgite clay talcum powder of preparation is applied outside, and second day itch disappears, red and swollen regression, and prickly heat disappeared on 3.
3rd, Lee, man, 11 years old, there was intensive sheet of prickly heat patient shirtfront, and surrounding is red and swollen, and itch is obvious.Use embodiment 3
The powder of preparation is applied outside, and itch mitigates, and second day prickly heat diminishes, and prickly heat on the 4th disappears, red and swollen regression, skin damaged heal.
Claims (1)
1. a kind of attapulgite clay talcum powder and preparation method thereof, it is characterised in that this method comprises the following steps：
Step 1: in mass ratio, weighing the raw material of following components：Attapulgite clay powder: calamine: folium artemisiae argyi: rhizoma atractylodis: the fruit of summer cypress:
The tuber of stemona: niacinamide: ethylene bis stearamide: ethanol=100:（1~4）∶（1~3）∶（1~4）∶（1~4）∶（1~3）∶（1~5）
∶（1~6）∶（100~150）；Raw material after above-mentioned weighing is added into wet grinding 1~2 hour in ball mill, pastel is obtained；
Step 2: the pastel drying that step one is obtained is then added to dry grinding in ball mill after removing ethanol, obtain recessed
Convex rod clay talcum powder.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710360556.5A CN107126401A (en) | 2017-05-21 | 2017-05-21 | A kind of attapulgite clay talcum powder and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710360556.5A CN107126401A (en) | 2017-05-21 | 2017-05-21 | A kind of attapulgite clay talcum powder and preparation method thereof |
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| CN107126401A true CN107126401A (en) | 2017-09-05 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201710360556.5A Pending CN107126401A (en) | 2017-05-21 | 2017-05-21 | A kind of attapulgite clay talcum powder and preparation method thereof |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN88105401A (en) * | 1988-04-30 | 1988-10-12 | 南京大学 | Mosquito-repellent powder and manufacture method thereof and application |
| CN1323615A (en) * | 2001-06-01 | 2001-11-28 | 周志伦 | Bathing talcum powder |
| CN105168385A (en) * | 2015-10-29 | 2015-12-23 | 卞国良 | Antibacterial and itching-relieving medicine composition and preparing method thereof |
-
2017
- 2017-05-21 CN CN201710360556.5A patent/CN107126401A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN88105401A (en) * | 1988-04-30 | 1988-10-12 | 南京大学 | Mosquito-repellent powder and manufacture method thereof and application |
| CN1323615A (en) * | 2001-06-01 | 2001-11-28 | 周志伦 | Bathing talcum powder |
| CN105168385A (en) * | 2015-10-29 | 2015-12-23 | 卞国良 | Antibacterial and itching-relieving medicine composition and preparing method thereof |
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Application publication date: 20170905 |