CN107108696B - 芋螺毒素肽κ-CPTx-btl05、其制备方法及应用 - Google Patents
芋螺毒素肽κ-CPTx-btl05、其制备方法及应用 Download PDFInfo
- Publication number
- CN107108696B CN107108696B CN201480083955.6A CN201480083955A CN107108696B CN 107108696 B CN107108696 B CN 107108696B CN 201480083955 A CN201480083955 A CN 201480083955A CN 107108696 B CN107108696 B CN 107108696B
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- CN
- China
- Prior art keywords
- cptx
- btl
- conotoxin
- kappa
- peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Public Health (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Plant Pathology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Description
Claims (7)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/CN2014/095199 WO2016101278A1 (zh) | 2014-12-26 | 2014-12-26 | 芋螺毒素肽κ-CPTx-btl05、其制备方法及应用 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN107108696A CN107108696A (zh) | 2017-08-29 |
CN107108696B true CN107108696B (zh) | 2021-01-15 |
Family
ID=56149005
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201480083955.6A Active CN107108696B (zh) | 2014-12-26 | 2014-12-26 | 芋螺毒素肽κ-CPTx-btl05、其制备方法及应用 |
Country Status (4)
Country | Link |
---|---|
US (1) | US20180201650A1 (zh) |
EP (1) | EP3239169B1 (zh) |
CN (1) | CN107108696B (zh) |
WO (1) | WO2016101278A1 (zh) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10858406B2 (en) * | 2014-09-30 | 2020-12-08 | Bgi Shenzhen Co., Limited | Conotoxin polypeptide κ-CPTx-bt105, and method for preparation thereof and application thereof |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0680696A (ja) * | 1992-09-01 | 1994-03-22 | Mitsubishi Kasei Corp | 新規ペプチド |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5672682A (en) * | 1996-03-18 | 1997-09-30 | University Of Utah Research Foundation | Conotoxin peptide PVIIA |
CN1169830C (zh) * | 1999-04-30 | 2004-10-06 | 解放军军事医学科学院生物工程研究所 | 芋螺毒素肽 |
WO2002064740A2 (en) * | 2001-02-09 | 2002-08-22 | Cognetix, Inc. | Cone snail peptides |
MXPA04010910A (es) * | 2002-05-03 | 2005-01-25 | Avecia Ltd | Procedimiento para la sintesis de peptidos. |
US10858406B2 (en) * | 2014-09-30 | 2020-12-08 | Bgi Shenzhen Co., Limited | Conotoxin polypeptide κ-CPTx-bt105, and method for preparation thereof and application thereof |
-
2014
- 2014-12-26 EP EP14908846.0A patent/EP3239169B1/en active Active
- 2014-12-26 CN CN201480083955.6A patent/CN107108696B/zh active Active
- 2014-12-26 WO PCT/CN2014/095199 patent/WO2016101278A1/zh active Application Filing
- 2014-12-26 US US15/539,763 patent/US20180201650A1/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0680696A (ja) * | 1992-09-01 | 1994-03-22 | Mitsubishi Kasei Corp | 新規ペプチド |
Non-Patent Citations (1)
Title |
---|
Characterizing the evolution and functions of the M-superfamily conotoxins;Zhou M 等;《Toxicon》;20130927;第76卷;第150-159页 * |
Also Published As
Publication number | Publication date |
---|---|
CN107108696A (zh) | 2017-08-29 |
EP3239169A4 (en) | 2018-06-20 |
EP3239169B1 (en) | 2024-04-17 |
EP3239169A1 (en) | 2017-11-01 |
US20180201650A1 (en) | 2018-07-19 |
WO2016101278A1 (zh) | 2016-06-30 |
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SE01 | Entry into force of request for substantive examination | ||
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Address after: Beishan Industrial Zone Building in Yantian District of Shenzhen city of Guangdong Province in 518083 Applicant after: BGI SHENZHEN Address before: Beishan Industrial Zone Building in Yantian District of Shenzhen city of Guangdong Province in 518083 Applicant before: BGI SHENZHEN |
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CB02 | Change of applicant information | ||
GR01 | Patent grant | ||
GR01 | Patent grant | ||
TR01 | Transfer of patent right |
Effective date of registration: 20220111 Address after: 518083 8th floor, building 11, Beishan Industrial Zone, 146 Beishan Road, Yangang community, Yantian street, Yantian District, Shenzhen, Guangdong Patentee after: BGI SHENZHEN Co.,Ltd. Address before: 518083 comprehensive building, Beishan Industrial Zone, Yantian District, Guangdong, Shenzhen Patentee before: BGI SHENZHEN |
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TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20230519 Address after: 518083 Peng Peng Road, Dapeng office, Dapeng New District, Shenzhen, Guangdong 7 Patentee after: Shenzhen Huada Sansheng Garden Technology Co.,Ltd. Address before: 518083 8th floor, building 11, Beishan Industrial Zone, 146 Beishan Road, Yangang community, Yantian street, Yantian District, Shenzhen, Guangdong Patentee before: BGI SHENZHEN Co.,Ltd. |
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TR01 | Transfer of patent right |