CN107001421B - 芋螺毒素肽κ-CPTx-btl02、其制备方法及应用 - Google Patents
芋螺毒素肽κ-CPTx-btl02、其制备方法及应用 Download PDFInfo
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- CN107001421B CN107001421B CN201480083950.3A CN201480083950A CN107001421B CN 107001421 B CN107001421 B CN 107001421B CN 201480083950 A CN201480083950 A CN 201480083950A CN 107001421 B CN107001421 B CN 107001421B
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- Prior art keywords
- cptx
- btl
- peptide
- kappa
- conotoxin peptide
- Prior art date
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Plant Pathology (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Public Health (AREA)
- Cell Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
Description
Claims (7)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/CN2014/095196 WO2016101275A1 (zh) | 2014-12-26 | 2014-12-26 | 芋螺毒素肽κ-CPTx-btl02、其制备方法及应用 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN107001421A CN107001421A (zh) | 2017-08-01 |
CN107001421B true CN107001421B (zh) | 2021-01-15 |
Family
ID=56149002
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201480083950.3A Active CN107001421B (zh) | 2014-12-26 | 2014-12-26 | 芋螺毒素肽κ-CPTx-btl02、其制备方法及应用 |
Country Status (4)
Country | Link |
---|---|
US (1) | US10246490B2 (zh) |
EP (1) | EP3239168B1 (zh) |
CN (1) | CN107001421B (zh) |
WO (1) | WO2016101275A1 (zh) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110075272B (zh) * | 2019-04-10 | 2022-08-02 | 中国人民解放军军事科学院军事医学研究院 | 芋螺多肽Bu8及其衍生多肽的应用 |
CN113694175A (zh) * | 2021-08-11 | 2021-11-26 | 深圳市萱嘉生物科技有限公司 | 苦参碱基离子液体芋螺毒素多肽溶液、制剂及其制备方法与应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0680696A (ja) * | 1992-09-01 | 1994-03-22 | Mitsubishi Kasei Corp | 新規ペプチド |
US5672682A (en) | 1996-03-18 | 1997-09-30 | University Of Utah Research Foundation | Conotoxin peptide PVIIA |
CN102190708B (zh) * | 2011-03-30 | 2013-05-08 | 中国人民解放军军事医学科学院生物工程研究所 | 一种桶形α芋螺多肽Bt1.3及其应用 |
EP3202776B1 (en) | 2014-09-30 | 2019-07-03 | BGI Shenzhen Co., Limited | Conotoxin polypeptide kappa-cptx-bt102, and method for preparation thereof and application thereof |
-
2014
- 2014-12-26 US US15/539,720 patent/US10246490B2/en active Active
- 2014-12-26 EP EP14908843.7A patent/EP3239168B1/en active Active
- 2014-12-26 WO PCT/CN2014/095196 patent/WO2016101275A1/zh active Application Filing
- 2014-12-26 CN CN201480083950.3A patent/CN107001421B/zh active Active
Also Published As
Publication number | Publication date |
---|---|
EP3239168A1 (en) | 2017-11-01 |
CN107001421A (zh) | 2017-08-01 |
US10246490B2 (en) | 2019-04-02 |
EP3239168B1 (en) | 2021-07-14 |
EP3239168A4 (en) | 2018-07-04 |
US20180162908A1 (en) | 2018-06-14 |
WO2016101275A1 (zh) | 2016-06-30 |
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Legal Events
Date | Code | Title | Description |
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PB01 | Publication | ||
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SE01 | Entry into force of request for substantive examination | ||
CB02 | Change of applicant information |
Address after: Beishan Industrial Zone Building in Yantian District of Shenzhen city of Guangdong Province in 518083 Applicant after: BGI SHENZHEN Address before: Beishan Industrial Zone Building in Yantian District of Shenzhen city of Guangdong Province in 518083 Applicant before: BGI SHENZHEN |
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CB02 | Change of applicant information | ||
GR01 | Patent grant | ||
GR01 | Patent grant | ||
TR01 | Transfer of patent right |
Effective date of registration: 20220104 Address after: 518083 8th floor, building 11, Beishan Industrial Zone, 146 Beishan Road, Yangang community, Yantian street, Yantian District, Shenzhen, Guangdong Patentee after: BGI SHENZHEN Co.,Ltd. Address before: 518083 comprehensive building, Beishan Industrial Zone, Yantian District, Guangdong, Shenzhen Patentee before: BGI SHENZHEN |
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TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20230506 Address after: 518083 Peng Peng Road, Dapeng office, Dapeng New District, Shenzhen, Guangdong 7 Patentee after: Shenzhen Huada Sansheng Garden Technology Co.,Ltd. Address before: 518083 8th floor, building 11, Beishan Industrial Zone, 146 Beishan Road, Yangang community, Yantian street, Yantian District, Shenzhen, Guangdong Patentee before: BGI SHENZHEN Co.,Ltd. |
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TR01 | Transfer of patent right |