CN107101947A - Disappear spuious electro-optical device and its method for work of CCD fluorescence biosensor chip scanners - Google Patents
Disappear spuious electro-optical device and its method for work of CCD fluorescence biosensor chip scanners Download PDFInfo
- Publication number
- CN107101947A CN107101947A CN201710531726.1A CN201710531726A CN107101947A CN 107101947 A CN107101947 A CN 107101947A CN 201710531726 A CN201710531726 A CN 201710531726A CN 107101947 A CN107101947 A CN 107101947A
- Authority
- CN
- China
- Prior art keywords
- light
- delustring
- darkroom
- spuious
- electro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/15—Preventing contamination of the components of the optical system or obstruction of the light path
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6402—Atomic fluorescence; Laser induced fluorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
Abstract
The present invention relates to disappear spuious electro-optical device and its method for work of CCD fluorescence biosensor chip scanners, including delustring darkroom, light limiting means, diaphragm and the attenuator set gradually from the bottom up, delustring darkroom upper end is provided with the pallet that can outwards extract out and for placing biochip, having on the downside of pallet on the downside of the ladder that is in the light stretched out, the ladder that is in the light has the light absorbent for being laid on delustring darkroom bottom side of the wall and bottom surface；Light limiting means, which include being located in the middle part of the seal closure of delustring darkroom upper end open, the tilting limited light block in side of seal closure, limit light block, to be provided with the through hole of sharp light direct projection to biochip on pallet；Diaphragm is arranged on the upper end of seal closure and positioned at the surface of pallet；Attenuator includes the delustring cylinder that axis is overlapped with the axis of diaphragm, and the madial wall of delustring cylinder sets delustring screw thread.The present invention is reasonable in design, can substantially eliminate the veiling glare in light path system, solves the problem of veiling glare easily floods fluorescence in Fluorescence Scanner detection.
Description
Technical field：
The present invention relates to disappear spuious electro-optical device and its method for work of a kind of CCD fluorescence biosensor chips scanner.
Background technology：
Patent（Application number：CN201610597471.4）A kind of micro-array chip fluorescence detection method of great power LED is proposed, its
It is characterised by exciting biochip by the annular LED illumination array of design, transmitting is then gathered using CCD camera
Fluorescence.Patent（Application number：CN02252864.4）Propose a kind of setting for CCD biochip supplies analysis with uniform illumination system
The white light that xenon lamp is sent, parallel monochromatic light is filtered into by optical element by meter, then oblique is mapped to its on biochip
Fluorescent dye is excited, then the fluorescence launched is captured with CCD camera.
Biochip technology is the new and high technology emerged rapidly in life science, and it is with slide, silicon chip or Buddhist nun
Dragons etc. are carrier, arrange substantial amounts of biomaterial to high-density on its surface, are realized to DNA, protein, cell and other lifes
Accurate, quick, parallel and large information capacity the detection and analysis of thing component, can be widely applied to drug research, medical diagnosis on disease, base
Because of fields such as function research.The detection mode of the current main flow of fluoroscopic examination of biochip has two kinds：One kind is to be based on
The mode of the laser co-focusing of photomultiplier, another is the imaging of high pressure xenon gas lamp, mercury lamp or high-power LED combined CCD
Mode.Wherein, CCD imaging modes are irradiated to the large area region of chip and made by the way that light source is filtered into narrowband wavelength ranges
Fluorescent marker is excited to produce fluorescence, then exposes collection by CCD camera, with simple in construction, the fast advantage of detection speed.
But CCD imaging modes have a problem that, that is, because the light source of high intensity disposably irradiates biochip
On so that substantial amounts of veiling glare is remained on light path system, as long as and seldom veiling glare just can be by biochip into CCD camera
On the fluorescence that emits flood.Therefore the present invention proposes a kind of design of the veiling glare that disappears of CCD fluorescence biosensor chips scanner,
The veiling glare on light path system can substantially be eliminated.
The content of the invention：
It is an object of the invention to for above weak point, there is provided a kind of veiling glare that disappears of CCD fluorescence biosensor chips scanner
Device and its method of work, reasonable in design can substantially eliminate the veiling glare on light path system.
To achieve these goals, the technical solution adopted by the present invention is：A kind of CCD fluorescence biosensor chips scanner disappears
Spuious electro-optical device, including delustring darkroom, light limiting means, diaphragm and the attenuator set gradually from the bottom up, the delustring are dark
The upper end of room is provided with one and can outwards extract out and be provided with laterally on the downside of the pallet of biochip, the pallet for placing
The ladder that is in the light of extension, the downside of the ladder that is in the light is provided with the light absorbent for being laid on delustring darkroom bottom side of the wall and bottom surface；
The light limiting means include a seal closure for being located at delustring darkroom upper end, and the side of the seal closure is obliquely installed limited light
The light direct projection in favor of excitation source is offered in the middle part of block, the limit light block to the through hole of biochip on pallet；It is described
Diaphragm is arranged on the upper end of seal closure and positioned at the surface of pallet；The attenuator is overlapped including an axis with the axis of diaphragm
Delustring cylinder, the upper end of the delustring cylinder is connected with CCD camera, and the madial wall of delustring cylinder sets delustring screw thread.
Further, the light absorbent is aterrimus extinction flannelette.
Further, the upper end in the delustring darkroom is provided with a chute, the chute is connected with tray both slid, and chute is opened
Mouth is located at the leading flank upper end in delustring darkroom；A light-transmitting opening passed through with sharp light is offered in the middle part of the pallet, it is described
The location indentations for being used to place biochip are symmetrically arranged with the middle part of the rear and front end of optical port.
Further, the upper end left and right sides of the seal closure is intilted inclined-plane, and the inclined-plane is used to install
Limit and a cylinder installation groove for being used to install excitation source, the installation groove are offered in the middle part of light block, the limit light block
Both sides be respectively arranged with a circular arc-shaped recess；The through hole is arranged on the middle part for installing groove, and through hole is square shape, through hole
Side wall is provided with internal thread.
Further, the diaphragm offers the loophole of a square shape in cylindrical in the middle part of diaphragm.
Further, the size of the loophole is identical with the size of microarray dot matrix on biochip.
Further, the top of the delustring screw thread is in 30 ° of tip shape.
A kind of method of work of the spuious electro-optical device that disappears of CCD fluorescence biosensor chips scanner of the present invention, during work：By biology
Chip is placed on pallet, and excitation source transmitting exciting light, limit light block veiling glare first larger to radiation angle in exciting light is carried out
Limitation, then veiling glare is through inside arrival delustring darkroom, the veiling glare in delustring darkroom passes through light absorbent after biochip
Absorb and be in the light reflection upwards after the blocking of ladder, and the veiling glare reflected upwards sequentially passes through the blocking of diaphragm, attenuator
Enter CCD camera after delustring, realize the veiling glare eliminated on light path system.
Compared with prior art, the present invention has the following effects that：Reasonable in design of the present invention, can substantially eliminate light path system
Veiling glare in system, solves the problem of veiling glare easily floods fluorescence in Fluorescence Scanner detection, and can also improve and sweep
Retouch instrument detection signal to noise ratio and sensitivity, lowering apparatus for filter performance rigors, so as to reduce purchase optical filter
Cost.
Brief description of the drawings：
Fig. 1 is the structural representation of the embodiment of the present invention；
Fig. 2 is the structural representation for limiting light block；
Fig. 3 is the workflow diagram of the embodiment of the present invention.
In figure：
1- delustrings darkroom；101- is in the light ladder；102- light absorbents；2- light limiting means；201- seal closures；202- limits light block；
203- installs groove；204- circular arc-shaped recess；205- through holes；206- internal threads；3- diaphragms；301- loopholes；4- attenuators；
401- delustring cylinders；402- delustring screw threads；5- pallets；501- light-transmitting openings；502- location indentations.
Embodiment:
The present invention will be further described in detail with reference to the accompanying drawings and detailed description.
As Figure 1-3, the spuious electro-optical device that disappears of a kind of CCD fluorescence biosensor chips scanner of the invention, including from lower past
On the delustring darkroom 1, light limiting means 2, diaphragm 3 and the attenuator 4 that set gradually, the upper end in the delustring darkroom 1 is provided with one
It can outwards extract and be used for the pallet 5 for placing biochip out, the downside of the pallet 5 is provided with the ladder that is in the light extended laterally
101, the downside of the ladder 101 that is in the light is provided with the light absorbent 102 for being laid on the bottom side of the wall of delustring darkroom 1 and bottom surface；It is described
Light limiting means 2 include a seal closure 201 for being located at the upper end of delustring darkroom 1, and the side of the seal closure 201 is obliquely installed limited
Light block 202, the middle part of the limit light block 202 offers light direct projection in favor of excitation source to biochip on pallet 5
Through hole 205；The diaphragm 3 is arranged on the upper end of seal closure 1 and positioned at the surface of pallet 5；The attenuator 4 includes an axis
The delustring cylinder 401 overlapped with the axis of diaphragm 3, the upper end of the delustring cylinder 401 is connected with CCD camera, delustring cylinder 401
Madial wall delustring screw thread 402 is set；During work, limit light block 202 is first limited the veiling glare at large radiation angle in excitation source
System, veiling glare enters in delustring darkroom 1 through biochip, and delustring darkroom 1 absorbs veiling glare, and then veiling glare sequentially passes through light
3 block of door screen, the absorption of attenuator 4, complete the elimination of veiling glare on light path system.
In the present embodiment, the light absorbent 102 is aterrimus extinction flannelette, and extinction works well.
In the present embodiment, the upper end in the delustring darkroom 1 is provided with a chute, and the chute is slidably connected with pallet 5, chute
Opening positioned at delustring darkroom 1 leading flank upper end；The middle part of the pallet 5 offers a light-transmitting opening passed through with sharp light
501, the rear and front end middle part of the light-transmitting opening 501 is symmetrically arranged with the location indentations 502 for being used to place biochip.
In the present embodiment, the upper end left and right sides of the seal closure 201 is intilted inclined-plane, and the inclined-plane is used for
Limit light block 202 is installed, the middle part of the limit light block 202 offers a cylinder for being used to install excitation source and installs groove 203,
The both sides for installing groove 203 are respectively arranged with a circular arc-shaped recess 204, it is ensured that excitation source is accurate, reliable installation；Institute
State through hole 205 and be arranged on the middle part for installing groove 203, through hole 205 is square shape, and the side wall of through hole 205 is provided with internal thread
206, the setting of internal thread 206 can prevent exciting light from producing interference, be easy to finally present in ccd image between bright dark phase
Provision.
Light argument setting of the size of the through hole according to used excitation source, is avoided that with the size for ensureing through hole
The light at large radiation angle enters light path so that exciting light is just only radiated at the effective coverage of biochip.
In the present embodiment, the diaphragm 3 is in cylinder, and the middle part of diaphragm 3 offers the loophole 301 of a square shape, institute
State the size of loophole 301 identical with the size of microarray dot matrix on biochip.
In the present embodiment, the top of the delustring screw thread 402 is in 30 ° of tip shape, is easy to more preferable delustring.
Specific implementation process：Biochip is placed on pallet 5, CCD camera is connected with attenuator 4, excitation source peace
On limit light block 202；Excitation source launches exciting light, and the veiling glare first larger to radiation angle in exciting light of limit light block 202 enters
Row limitation, then veiling glare is through inside arrival delustring darkroom 1, the veiling glare in delustring darkroom 1 passes through extinction after biochip
Material 102 absorbs and is in the light reflection upwards after the blocking of ladder 101, and the veiling glare reflected upwards sequentially passes through the screening of diaphragm 3
Enter CCD camera after gear, the delustring of attenuator 4, realize the veiling glare eliminated on light path system.
A kind of method of work of the spuious electro-optical device that disappears of CCD fluorescence biosensor chips scanner of the present invention, during work：By biology
Chip is placed on pallet 5, excitation source transmitting exciting light, the veiling glare first larger to radiation angle in exciting light of limit light block 202
Limited, then veiling glare is passed through and reached after biochip inside delustring darkroom 1, and the veiling glare in delustring darkroom 1 is by inhaling
Luminescent material 102 absorbs and is in the light reflection upwards after the blocking of ladder 101, and the veiling glare reflected upwards sequentially passes through diaphragm 3
Block, enter CCD camera after the delustring of attenuator 4, realize the veiling glare eliminated on light path system.
The foregoing is only presently preferred embodiments of the present invention, all equivalent changes done according to scope of the present invention patent with
Modification, should all belong to the covering scope of the present invention.
Claims (8)
1. a kind of spuious electro-optical device that disappears of CCD fluorescence biosensor chips scanner, it is characterised in that：Including setting gradually from the bottom up
Delustring darkroom, light limiting means, diaphragm and attenuator, the upper end in the delustring darkroom, which is provided with one, outwards to extract out and be used for
Place and be provided with the ladder that is in the light extended laterally on the downside of the pallet of biochip, the pallet, it is described to be in the light under ladder
Side is provided with the light absorbent for being laid on delustring darkroom bottom side of the wall and bottom surface；The light limiting means are located at delustring darkroom including one
The seal closure of upper end, the side of the seal closure, which is obliquely installed in the middle part of limited light block, the limit light block, to be offered to swash
Through hole of the light direct projection of light emitting source to biochip on pallet；The diaphragm is arranged on the upper end of seal closure and positioned at pallet
Surface；The attenuator includes the delustring cylinder that an axis is overlapped with the axis of diaphragm, the upper end of the delustring cylinder and CCD
Camera is connected, and the madial wall of delustring cylinder sets delustring screw thread.
2. the spuious electro-optical device that disappears of CCD fluorescence biosensor chips scanner according to claim 1, it is characterised in that：It is described
Light absorbent is aterrimus extinction flannelette.
3. the spuious electro-optical device that disappears of CCD fluorescence biosensor chips scanner according to claim 1, it is characterised in that：It is described
The upper end in delustring darkroom is provided with a chute, and the chute is connected with tray both slid, and the opening of chute is located at the front side in delustring darkroom
Face upper end；It is right in the middle part of a light-transmitting opening passed through with sharp light, the rear and front end of the light-transmitting opening to be offered in the middle part of the pallet
Claim to be provided with the location indentations for being used to place biochip.
4. the spuious electro-optical device that disappears of CCD fluorescence biosensor chips scanner according to claim 1, it is characterised in that：It is described
The upper end left and right sides of seal closure is intilted inclined-plane, and the inclined-plane is used to install in limit light block, the limit light block
Portion offers a cylinder for being used to install excitation source and installs groove, and the both sides of the installation groove are respectively arranged with a circular arc
Shape recess；The through hole is arranged on the middle part for installing groove, and through hole is square shape, and the side wall of through hole is provided with internal thread.
5. the spuious electro-optical device that disappears of CCD fluorescence biosensor chips scanner according to claim 1, it is characterised in that：It is described
Diaphragm offers the loophole of a square shape in cylindrical in the middle part of diaphragm.
6. the spuious electro-optical device that disappears of CCD fluorescence biosensor chips scanner according to claim 5, it is characterised in that：It is described
The size of loophole is identical with the size of microarray dot matrix on biochip.
7. according to the spuious electro-optical device that disappears of CCD fluorescence biosensor chips scanner according to claim 1, it is characterised in that：
The top of the delustring screw thread is in 30 ° of tip shape.
8. a kind of method of work of the spuious electro-optical device that disappears of CCD fluorescence biosensor chips scanner, it is characterised in that：Using such as right
It is required that the spuious electro-optical device that disappears of 1~7 any described CCD fluorescence biosensor chip scanners, during work：Biochip is placed on
On pallet, excitation source transmitting exciting light, limit light block veiling glare first larger to radiation angle in exciting light is limited, then miscellaneous
Astigmatism is passed through and reached after biochip inside delustring darkroom, and the veiling glare in delustring darkroom absorbs and is in the light by light absorbent
Reflection upwards after the blocking of ladder, the veiling glare reflected upwards enters CCD after sequentially passing through the blocking of diaphragm, the delustring of attenuator
Camera, realizes the veiling glare eliminated on light path system.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710531726.1A CN107101947B (en) | 2017-07-03 | 2017-07-03 | Stray light eliminating device of CCD biochip fluorescence scanner and working method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710531726.1A CN107101947B (en) | 2017-07-03 | 2017-07-03 | Stray light eliminating device of CCD biochip fluorescence scanner and working method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107101947A true CN107101947A (en) | 2017-08-29 |
| CN107101947B CN107101947B (en) | 2023-03-21 |
Family
ID=59663375
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710531726.1A Active CN107101947B (en) | 2017-07-03 | 2017-07-03 | Stray light eliminating device of CCD biochip fluorescence scanner and working method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107101947B (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107606531A (en) * | 2017-09-21 | 2018-01-19 | 武汉优炜星科技有限公司 | A kind of parallel spot light of UV LED |
| CN109520930A (en) * | 2018-12-29 | 2019-03-26 | 苏州汶颢微流控技术股份有限公司 | A kind of elisa assay instrument |
| CN111089650A (en) * | 2019-12-25 | 2020-05-01 | 中国科学院合肥物质科学研究院 | Solar blind area high-resolution low-dispersion grating spectrometer |
| CN111879408A (en) * | 2020-06-18 | 2020-11-03 | 武汉高芯科技有限公司 | Light blocking ring with stray light inhibiting function, cold screen and refrigeration type infrared detector |
| CN112014282A (en) * | 2020-08-27 | 2020-12-01 | 苏州亿利安机电科技有限公司 | On-line detection device of direct-reading dust concentration measuring instrument |
| WO2020252768A1 (en) * | 2019-06-21 | 2020-12-24 | 维克多哈苏有限公司 | Adapter device and camera |
| CN112710385A (en) * | 2020-11-26 | 2021-04-27 | 上海航天控制技术研究所 | Optical trap for photoelectric sensor test |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2549460Y (en) * | 2002-06-09 | 2003-05-07 | 浙江大学 | Biological clip analyzer |
| CN201477048U (en) * | 2009-07-23 | 2010-05-19 | 江苏天瑞仪器股份有限公司 | Device for reducing optical background and noise of atomic fluorescence spectroscopy |
| CN105092219A (en) * | 2015-09-21 | 2015-11-25 | 上海卫星工程研究所 | System-level stray light test unit attenuator |
| WO2016197300A1 (en) * | 2015-06-08 | 2016-12-15 | 杜晨光 | High-precision microminiaturized particle sensor |
| CN106289323A (en) * | 2016-08-31 | 2017-01-04 | 上海航天控制技术研究所 | The optical texture frock of the anti-Stray Light Test of star sensor and method of testing |
-
2017
- 2017-07-03 CN CN201710531726.1A patent/CN107101947B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2549460Y (en) * | 2002-06-09 | 2003-05-07 | 浙江大学 | Biological clip analyzer |
| CN201477048U (en) * | 2009-07-23 | 2010-05-19 | 江苏天瑞仪器股份有限公司 | Device for reducing optical background and noise of atomic fluorescence spectroscopy |
| WO2016197300A1 (en) * | 2015-06-08 | 2016-12-15 | 杜晨光 | High-precision microminiaturized particle sensor |
| CN105092219A (en) * | 2015-09-21 | 2015-11-25 | 上海卫星工程研究所 | System-level stray light test unit attenuator |
| CN106289323A (en) * | 2016-08-31 | 2017-01-04 | 上海航天控制技术研究所 | The optical texture frock of the anti-Stray Light Test of star sensor and method of testing |
Non-Patent Citations (1)
| Title |
|---|
| 翟珊珊: "平面光栅杂散光测试仪模型设计及消杂光技术研究" * |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107606531A (en) * | 2017-09-21 | 2018-01-19 | 武汉优炜星科技有限公司 | A kind of parallel spot light of UV LED |
| CN109520930A (en) * | 2018-12-29 | 2019-03-26 | 苏州汶颢微流控技术股份有限公司 | A kind of elisa assay instrument |
| WO2020252768A1 (en) * | 2019-06-21 | 2020-12-24 | 维克多哈苏有限公司 | Adapter device and camera |
| CN112243502A (en) * | 2019-06-21 | 2021-01-19 | 维克多哈苏有限公司 | Switching device and camera |
| CN112243502B (en) * | 2019-06-21 | 2022-03-15 | 维克多哈苏有限公司 | Switching device and camera |
| CN111089650A (en) * | 2019-12-25 | 2020-05-01 | 中国科学院合肥物质科学研究院 | Solar blind area high-resolution low-dispersion grating spectrometer |
| CN111089650B (en) * | 2019-12-25 | 2022-03-08 | 中国科学院合肥物质科学研究院 | Solar blind area high-resolution low-dispersion grating spectrometer |
| CN111879408A (en) * | 2020-06-18 | 2020-11-03 | 武汉高芯科技有限公司 | Light blocking ring with stray light inhibiting function, cold screen and refrigeration type infrared detector |
| CN112014282A (en) * | 2020-08-27 | 2020-12-01 | 苏州亿利安机电科技有限公司 | On-line detection device of direct-reading dust concentration measuring instrument |
| CN112014282B (en) * | 2020-08-27 | 2023-11-24 | 苏州亿利安机电科技有限公司 | On-line detection device of direct-reading dust concentration measuring instrument |
| CN112710385A (en) * | 2020-11-26 | 2021-04-27 | 上海航天控制技术研究所 | Optical trap for photoelectric sensor test |
| CN112710385B (en) * | 2020-11-26 | 2023-11-10 | 上海航天控制技术研究所 | Optical trap for photoelectric sensor test |
Also Published As
| Publication number | Publication date |
|---|---|
| CN107101947B (en) | 2023-03-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN107101947A (en) | Disappear spuious electro-optical device and its method for work of CCD fluorescence biosensor chip scanners | |
| JP7343551B2 (en) | Device for reading IVD assays | |
| RU2665121C2 (en) | Light source with adapted spectral distribution | |
| CN107850537B (en) | Radiation carrier and use thereof in an optical sensor | |
| CN106092994B (en) | A kind of micro-array chip fluorescence detection method of great power LED | |
| CN101305304A (en) | Sensitive emission light gathering and detection system | |
| CN101346622A (en) | Method and also measurement system for determining the oxygen partial pressure distribution in at least one tissue surface section, in particular skin tissue surface section | |
| US20120179383A1 (en) | Disc and calibration method of test device using the same | |
| US20120301872A1 (en) | System and method for increased fluorescence detection | |
| JP2020536223A (en) | Light energy fluorescence excitation | |
| CN206974888U (en) | The spuious electro-optical device that disappears of CCD fluorescence biosensor chip scanners | |
| KR20030037314A (en) | Apparatus for analyzing fluorescence image of biochip | |
| CN108363260B (en) | Low-contrast-glare fluorescent powder LED light source and camera device with same | |
| JP2005274355A (en) | Fluorescence image acquisition device | |
| WO2020253518A1 (en) | Continuous ultraviolet excitation fluorescence spectrum filtering immunoassay method | |
| US20090170214A1 (en) | Luminescent Reporter Modality for Analyzing an Assay | |
| CN107543806A (en) | Multi-channel fluorescence detection system and method thereof | |
| KR20210011686A (en) | Diagnostic analysis apparatus using fluorescent diodegradation | |
| US20060281190A1 (en) | Analyte detection using luminescence concentration | |
| CN207992061U (en) | A kind of high-flux medicaments sifting imaging device | |
| CN214781826U (en) | PCR detector | |
| CN111413327A (en) | Dual mode detection system and dual mode detection method | |
| CN217820406U (en) | Reagent kit | |
| JP5970340B2 (en) | Spectroscopic measurement system and spectral measurement method | |
| KR101716217B1 (en) | Apparatus and Method for inspect component |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |