CN107088112A - One kind is through conduit aortic valve - Google Patents
One kind is through conduit aortic valve Download PDFInfo
- Publication number
- CN107088112A CN107088112A CN201710351059.9A CN201710351059A CN107088112A CN 107088112 A CN107088112 A CN 107088112A CN 201710351059 A CN201710351059 A CN 201710351059A CN 107088112 A CN107088112 A CN 107088112A
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- China
- Prior art keywords
- valve
- valve frame
- location division
- frame
- conduit
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2427—Devices for manipulating or deploying heart valves during implantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2409—Support rings therefor, e.g. for connecting valves to tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
- A61F2/2418—Scaffolds therefor, e.g. support stents
Abstract
The present invention provides one kind through conduit aortic valve, it includes valve frame, leaflet and valve skirt, the leaflet and valve skirt are separately positioned on the valve frame, the valve frame radial contraction and can be expanded and with flowing into end and outflow end, at least one outward location division of outer wall from the valve frame is provided with the outer wall of the valve frame, one end of the location division is fixed on the outer wall of the valve frame, and the other end of the location division is the free end that end is flowed into towards the valve frame.The present invention's can be positioned in annulus and its surrounding tissue well through conduit aortic valve, so as to reduce the movement under blood flow impact to ventricle direction；In addition, the valve can realize the resetting and recovery of implantation process, and can the simple induction system of mating structure, possess preferable operation technique.
Description
Technical field
The invention belongs to technical field of medical instruments, and in particular to one kind is through conduit aortic valve.
Background technology
Aortic valve disease is a kind of common heart valve disease, and its incidence of disease gradually rises with the increase at age
It is high.At present, generally using diseased valve progress Prosthetic valve replacement surgically to patient, but which is simultaneously
Be not suitable for part it is older, with merge disease the problems such as patient.For above-mentioned patient, it can use minimally invasive through conduit
Aortic valve implantation carries out Prosthetic valve replacement, due to that need not open chest through conduit valve implantation, has
The advantages of wound is small, rehabilitation is fast, therefore by more and more extensive concern and pay attention to.
Delivery mode through conduit aortic valve can be divided into balloon expandable mode and self-inflated expansion pattern.Balloon expandable
Mode places sacculus in through conduit aortic valve, and valve expands sacculus after being inputted in vivo by induction system by pressurization
, and then drive valve to expand and be anchored on lesion locations；Self-inflated expansion pattern passes through through conduit aortic valve valve frame material
The inherent characteristic of material realizes expansion, is radially compressed and is placed in induction system conduit and is entering body through conduit aortic valve
After interior, because conduit is recalled so as to self-expanding into original size in the case of unconfined so as to being anchored on lesion locations.
After implanting, through conduit aortic valve mainly by during impulsive force from ventricular contraction to sustainer direction and
Arterial blood pushes power effect to it to ventricle direction during ventricular diastole.Due to above-mentioned special mode of movement, valve is in implantation
After can not be sutured between annulus, valve is completely dependent on its valve frame itself outwardly radial support force and is fixed on aorta petal
Ring position is so as to realize fixation.Radial support power such as valve frame is too small, then the positioning relative difficulty on aortic valvular ring, valve
Easily washed away by blood flow；Radial support power such as valve frame is excessive, then damage is easily caused to annulus and sustainer, and also unfavorable
Conveyed in valve is compressed into conduit.
In consideration of it, being mainly used in the patient of aortostenosis caused by retrogression pathological changes, such disease through conduit valve at present
People's leaflet and annulus calcification are serious, and the calcification point existed through conduit valve after implanting using patient's fixed position is aided in
Positioning, although which can aid in positioning and fixation of the valve in annulus to a certain extent, but for backflowing merely
The some patientss such as type are still had because without calcification point the problems such as location difficulty.
In addition, when using conduit conveying through conduit aortic valve, valve is reached after lesion locations start release, if
It was found that off-position is inaccurate, it usually needs take in induction system valve again, then discharged again；However, existing
What is had generally can not be reclaimed and be repositioned after off-position is incorrect through conduit aortic valve, in addition for carrying out
The induction system structure of valve conveying is relative complex, so as to increase the difficulty of actual operation operation.
Therefore, especially expect that one kind can be preferably positioned to reduce under blood flow impact to the generation of ventricle direction
Movement, can be achieved implantation process resetting and recovery, possess preferable operation technique and can mating structure letter
Single induction system through conduit aortic valve.
The content of the invention
The present invention provides one kind through conduit aortic valve, and it can be positioned in annulus and its surrounding tissue well,
So as to reduce the movement under blood flow impact to ventricle direction；In addition, the valve can realize the resetting of implantation process
And recovery, and can the simple induction system of mating structure, possess preferable operation technique.
The present invention provides one kind and distinguished through conduit aortic valve, including valve frame, leaflet and valve skirt, the leaflet and valve skirt
It is arranged on the valve frame,
The valve frame radial contraction and can be expanded and with end and outflow end is flowed into, be set on the outer wall of the valve frame
There is at least one outward location division of outer wall from the valve frame, one end of the location division is fixed on the outer of the valve frame
On wall, the other end of the location division is the free end that end is flowed into towards the valve frame.
Further, the valve frame flows into the radial support power of the radial support power more than outflow end at end.
Further, the valve frame is the tubular frame being made up of multiple quadrilateral units and multiple hexagonal cells.
Further, the location division is in linear, V-arrangement or U-shaped.
Further, it is coated with medical flexible material in the end of the location division free end.
Further, the free end of the location division is connected by connector with the valve frame.
Further, the connector for any bio-compatible suture or drawn from valve frame with valve frame one company
Connect beam.
Further, the outward amplitude in the free end of the location division is 0.5-2mm, the free end of the location division
It is 4-13mm with the distance between the inflow end of the valve frame.
Further, it is embedded with developing apparatus in the end of the location division free end.
Further, it is used for the fixed part with induction system fixation provided with more than one in the valve frame outflow end.
Further, the outer at the free end close to the inflow end can be set directly down, or tilt certain angle
Degree is down-set.
Further, sealed skirt is provided with the outside of the valve skirt, the sealed skirt is circumferentially provided on the outer of the valve frame
On wall.
The present invention through conduit aortic valve, by set on the outer wall of valve frame at least one from the outer wall of valve frame to
The location division opened outside, because the location division has towards inflow end and outward free end, therefore in the stream of valve frame
While going out end and be fixed on human aortic annulus position, location division can be located and fixed within around human aortic annulus
Tissue, so as to reduce the risk of the centripetal indoor sport of valve.
Further, since the free end of location division is set towards end is flowed into, and when valve discharges from induction system, the stream of valve frame
Enter end release in advance, and outflow end is still retained in the conduit of induction system with compressive state；When valve off-position is inaccurate
So as to need to reclaim during valve, valve can be driven to be re-compressed from inflow end to outflow end and load induction system by conduit
It is interior, so as to realize resetting and recovery of the valve in implantation process.
Particularly, of the invention can be that can be achieved to valve using common induction system through conduit aortic valve
Conveying and position, it need not increase the diameter of induction system conduit without set the structural member of complexity in induction system,
So as to possess preferable operation technique.
Brief description of the drawings
Fig. 1 is the structural representation through conduit aortic valve of an embodiment of the present invention；
Fig. 2 is the front view of the valve frame of an embodiment of the present invention；
Fig. 3 is the front view of the valve frame of another embodiment of the invention；
Fig. 4 is the front view of the valve frame of a further embodiment of the present invention；
Fig. 5 is the top view of the valve frame of an embodiment of the present invention；
Fig. 6 is the structural representation of the location division of an embodiment of the present invention；
Fig. 7 is the attachment structure schematic diagram of the connector of an embodiment of the present invention；
Fig. 8 is the attachment structure schematic diagram of the connector of another embodiment of the invention；
Fig. 9 is the attachment structure schematic diagram of the connector of a further embodiment of the present invention；
Figure 10 is the mounting structure schematic diagram of the developing apparatus of an embodiment of the present invention；
Figure 11 is the structural representation of the fixed part of an embodiment of the present invention.
Description of reference numerals：
1：Valve frame；11：Flow into end；12：Outflow end；2：Leaflet；3：Valve skirt；4：Location division；41：Free end；42：Curb girder；
5：Connector；6：Developing apparatus；7：Sealed skirt；8：Fixed part；9：Suture；10、101、102、103：Node；A：Amplitude；D：Away from
From.
Embodiment
To make the object, technical solutions and advantages of the present invention clearer, accompanying drawing and implementation below in conjunction with the present invention
Example, the technical scheme in the embodiment of the present invention is clearly and completely described, it is clear that described embodiment is the present invention
A part of embodiment, rather than whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art are not having
The every other embodiment obtained under the premise of creative work is made, the scope of protection of the invention is belonged to.
It is of the invention through conduit aortic valve (hereinafter referred to as valve) with reference to shown in Fig. 1 to Figure 11, including valve frame 1,
Leaflet 2 and valve skirt 3, leaflet 2 and valve skirt 3 are circumferentially provided on valve frame 1 respectively, valve frame 1 can radial contraction and expand and have
There are inflow end 11 and outflow end 12, at least one outward location division of outer wall from valve frame 1 is provided with the outer wall of valve frame 1
4, one end of location division 4 is fixed on the outer wall of valve frame 1, and the other end of location division 4 is towards the free end 41 for flowing into end 11.
In the present invention, it is to be understood that valve frame 1 be it is a kind of can radial contraction and expansion tubular frame construction.
When using induction system conveying through conduit aortic valve, valve compression is set to load delivery system by the radial contraction of valve frame 1
In the conduit of system, consequently facilitating the conveying of valve；After internal specified location is entered, induction system release valve now leads to
Crossing the radial dilatation of valve frame 1 makes valve be positioned in human aortic annulus.
The present invention is set to the outflow end 12 of valve frame 1 close to one end of sustainer after being implanted into through conduit aortic valve, will
The inflow end 11 of valve frame 1 is set to after being implanted into through conduit aortic valve close to one end of left ventricle；It is understood that outflow end
12 are located at the axial direction of valve frame 1 with end 11 is flowed into.Wherein, the outflow end 12 of valve frame 1 is used to fix with induction system, consequently facilitating defeated
System is sent to be delivered to the lesion locations of patient through conduit aortic valve；The inflow end 11 of valve frame 1 is through conduit aorta petal
The position that film is fixed with human aortic annulus, valve frame 1 is located and fixed within human aortic annulus after being radially expanded
On position.
In one embodiment, the radial support power that valve frame 1 can be flowed into end 11 is set greater than the footpath of outflow end 12
To support force.Valve frame 1 flow into end 11 have larger radial support power, consequently facilitating in use with human aortic valve
Ring is fixed；The outflow end 12 of valve frame 1 has less radial support power, consequently facilitating valve is loading conveying using preceding compression
In system.The concrete numerical value scope that the radial support power of end 11 and outflow end 12 is flowed into valve frame 1 does not make considered critical, valve frame 1
As long as valve good location and will not be to human body valve in human aortic annulus can be made by flowing into the radial support power at end 11
The tissue such as ring and sustainer causes damage, does not influence compression and release of the valve in induction system in addition；Valve frame 1 flows out
As long as the radial support power at end 12 is easy to valve to load induction system.In addition, flowing into end 11 and outflow end 12 to valve frame 1
Outer circumference diameter does not make strict limitation, can rationally be set according to actual conditions；For example, can be straight by the periphery of the outflow end 12 of valve frame 1
Footpath is set greater than flowing into end 11.
In the present invention, if valve frame 1 can radial contraction and expansion consequently facilitating the installation and positioning of valve, right
Its concrete structure does not make considered critical.As shown in Figures 2 and 3, valve frame 1 can be by multiple quadrilateral units and multiple hexagons
The tubular frame that unit is constituted；Specifically, quadrilateral units can be surrounded by four beams, and hexagonal cells can be enclosed by six beams
Into the junction between Liang Yuliang forms node 10.To constituting each quadrilateral units of valve frame 1 and the size of hexagonal cells
(such as the length of side, angle) does not make strict limitation, and the size of each unit can rationally be set according to actual needs with identical or different
Put.
It is understood that can be by the way that the quantity for constituting the beam that valve frame 1 flows into end 11 be set greater than to constitute valve frame 1
The quantity of the beam of outflow end 12, so that valve frame 1 flows into the radial support power of the radial support power more than outflow end 12 at end 11；This
Outside, it can be more than the size of the unit of 1 outflow end of composition valve frame 12 and constitute the size that valve frame 1 flows into the unit of end 11, so that valve
The outer circumference diameter of the outflow end 12 of frame 1, which is more than, flows into end 11.
As shown in Fig. 2 in one embodiment, valve frame 1 is from end 11 is flowed into settable five stringers of outflow end 12, first row
The quantity (not including the curb girder of location division 4) of beam to the 5th stringer beam in a circumferential direction can set gradually for：24,18
It is individual, 9,18,12.Wherein, the first stringer continuous V-arrangement unit formed that can be joined end to end by 12 is constituted；Second row
Beam can be made up of 9 inverted V-shaped units, and it can surround 9 diamond-shaped elements (i.e. with 9 V-arrangement units in the first stringer respectively
Small diamond-shaped element), other 3 V-arrangement units in the first stringer can be distributed on circumferencial direction (to be had between i.e. every 3 diamond-shaped elements
There is a V-arrangement unit)；3rd stringer can be made up of the vertical beam at 9 intervals；4th stringer can be made up of 9 V-arrangement units,
It is (i.e. small that it can surround 6 hexagonal cells jointly with 9 vertical beams in 9 in the second stringer inverted V-shaped unit and the 3rd stringer
Hexagonal cells)；Each beam in 5th stringer can surround 6 big diamond-shaped element with the 4th stringer, now valve frame 1 outflow end 12
Outer circumference diameter, which is more than, flows into end 11.It is understood that under above-mentioned set-up mode, valve frame 1 can be formed in a circumferential direction
Three uniform big hexagonal cells.
As shown in figure 3, in another embodiment, can also be in the first stringer on the basis of the above-mentioned structure of valve frame 1
Lower section one side of the second stringer (i.e. away from) is set up a row and joined end to end by 12 the grid list that the continuous V-arrangement unit formed constitutes
Member, it can surround 12 diamond-shaped elements (i.e. small diamond-shaped element) with the first stringer, so that further improving valve frame 1 flows into end 11
Radial support power.
As shown in figure 4, in a further embodiment, above-mentioned second stringer can also be joined end to end by 12 formed it is continuous
Inverted V-shaped unit is constituted, and it can surround 12 diamond-shaped elements (i.e. small rhombus list with 12 V-arrangement units in the first stringer respectively
Member).Now, 9 vertical beams in the 3rd stringer are connected with the upper end of 9 diamond-shaped elements in above-mentioned 12 diamond-shaped elements, and in addition 3
Individual diamond-shaped element is uniform in a circumferential direction.Particularly, the upper end of 3 diamond-shaped elements forms free end in addition, and it can increase
Valve skirt 3 sutures fixed route, so that valve skirt 3 is more securely fixed on valve frame 1.
The present invention does not make strict limitation to the molding mode of above-mentioned valve frame 1, for example can be by tubing through laser cutting, sizing
Processed etc. technique；The material of valve frame 1 can be the material of plastically deformable, such as can be used medical Nitinol.
Above-mentioned valve frame 1 at low temperature can 360 ° it is isometrical be compressed in diameter 5mm or so conduit, implant release valve when, valve
Frame 1 can recover in duct free restraining force to free state (free state is as shown in Figures 2 and 3), so that valve is positioned.
In the present invention, location division 4 is used for auxiliary positioning and the tissue being fixed on around human aortic annulus；Can be with
Understand, the free end 41 of location division 4 be connected with the other parts such as valve frame 1, and the external diameter of the free end 41 of location division 4 is answered
When the external diameter that end 11 is flowed into more than valve frame 1, consequently facilitating being fixed on human aortic annulus position at the inflow end 11 of valve frame 1
Meanwhile, location division 4 can be located and fixed within the tissue around human aortic annulus.
The present invention does not make strict limitation to the concrete structure of location division 4, as long as it is flared out simultaneously with respect to the outer wall of valve frame 1
And with the free end 41 towards the inflow of valve frame 1 end 11 consequently facilitating auxiliary positioning.As shown in Figure 5 and Figure 6, implement one
In mode, location division 4 can be with V-shaped；Specifically, outward curb girder 42 can be drawn respectively on two beams of valve frame 1,
The end of two curb girders 42 links to form V-arrangement location division, and its tip constitutes the free end 41 of location division 4；Particularly, two
The end of curb girder 42 can be with rounding off, so as to avoid damage to human aortic annulus surrounding tissue.
In another embodiment, location division 4 can also be in linear；Specifically, one can be drawn on the beam of valve frame 1
Outward curb girder 42, the curb girder 42 constitutes linear location division, and its end is the free end 41 of location division 4.Other
In embodiment, location division 4 can also take the shape of the letter U；Specifically, it can draw outward respectively on two beams of valve frame 1
Curb girder 42, the end of two curb girders 42 links to form U-shaped location division by circular arc, and the circular arc is the free end for constituting location division 4
41。
The present invention does not make strict limitation to the concrete structure of above-mentioned curb girder 42, in order that valve has good radial contraction
And spreading performance, round and smooth processing can be carried out to curb girder 42；For example, curb girder 42 can be by multistage straight line and/or arc structure structure
Into can be with rounding off between multi-segment structure.Specifically, as shown in fig. 6, in one embodiment, curb girder 42 can be by three sections
Structure is constituted；Wherein first paragraph can be inside arc structure, so as to the outer wall for valve frame 1 of more fitting, be conducive to valve
It is radially compressed in the conduit of induction system；The linear structure that second segment can be expanded outwardly, consequently facilitating auxiliary positioning is in people
Tissue around body aortic valvular ring；3rd section can be export-oriented linear structure (i.e. from second segment end always to extension
Stretch) or downward linear structure.Particularly, when being set to downward linear structure by the 3rd section, the 3rd section can also be made
End slopes inwardly, so as to play a part of preventing plowing from tissue, inside angle of inclination can be less than 30 °.
The present invention does not make strict limitation to set location of the above-mentioned location division 4 on the outer wall of valve frame 1, as long as can realize
Auxiliary positioning in human aortic annulus surrounding tissue and damage will not be caused i.e. to human aortic annulus surrounding tissue
Can, location division 4 can for example be arranged on the outside of the big hexagonal cells of valve frame 1.Particularly, as shown in fig. 6, location division 4 is free
It can be 0.5-2mm to hold 41 outward amplitude As, and the free end 41 of location division 4 can be 4- with flowing into the distance between end 11 D
13mm；The scope ensure that location division 4 is positioned in human aortic annulus surrounding tissue well, and be difficult to human body
Aortic valvular ring surrounding tissue causes damage.
In addition, the specific setting quantity to location division 4 does not make strict limitation, for example, it could be arranged to 2-6, preferably 3
Individual or 6, more than two location divisions 4 can be distributed on the circumferencial direction of the outer wall of valve frame 1, so as to preferably be positioned at
In human aortic annulus surrounding tissue.
Further, medical flexible material can also be coated in the end of the free end 41 of location division 4, so as to reach preferably
Anti-scratch effect, is further protected to tissue formation.Medical flexible material conventional material such as can be cloth, pericardial tissue
Material.
Particularly, in order to avoid the free end 41 of location division 4 is shunk in valve frame 1 and is outwardly or inwardly excessively prolonged in process of expansion
Stretch or expand, the free end 41 of location division 4 can be connected by connector 5 with valve frame 1；To the concrete structure of connector 5 and
Set-up mode does not make strict limitation, as long as not influenceing the auxiliary positioning function of location division 4 and can have to location division 4 certain
Restriction effect.
As shown in fig. 7, in one embodiment, connector 5 could be arranged to suture；Can be by suture by location division 4
Free end 41 and valve frame 1 Node connectedness it is spacing so as to be carried out to it.Specifically, suture can be drawn in the node of valve frame 1, drawn
The suture gone out can be connected with the free end 41 of location division 4；Wherein, the material of suture can for polyester, polytetrafluoro, polyethylene or other
Medical material.It is understood that suture can be arranged on more than one node of valve frame 1, such as 1-3, i.e. location division 4
Both it can be connected with a node of valve frame 1 by suture, two or three nodes that can also be simultaneously with valve frame 1 pass through suture
Connection；Wherein, link node can be the knot positioned at the lower section of 4 free end of location division 41 (side that end is flowed into close to valve frame 1)
Point, such as node 101, node 102, node 103.
As shown in Figure 8 and Figure 9, in another embodiment, connector 5 can also be single-beam；One end of single-beam can be consolidated
On the beam for being scheduled on valve frame 1, the other end of single-beam can be fixed on the curb girder 42 of location division 4.To fixation of the single-beam on valve frame 1
Position does not make strict limitation, for example, can be fixed on the node 10 of valve frame 1 (as shown in Figure 8), may be also secured at valve frame 1
On vertical beam (as shown in Figure 9)；Size (such as width) to the single-beam does not make strict limitation, can be equal to or less than and constitute valve
The size of the beam of frame 1.Particularly, above-mentioned single-beam can also increase the suture fixed route of valve skirt 3, so that valve skirt 3 can be more steady
Admittedly be fixed on valve frame 1.
The present invention does not make strict limitation to the setting quantity of connector 5, can rationally be set according to actual conditions；For example can be with
Two are set, two curb girders 42 of location division 4 can be connected on valve frame 1 by two connectors 5 respectively.In addition, in the present invention
In, above-mentioned location division 4 and connector 5 (situation of single-beam) can be integrally formed with valve frame 1, consequently facilitating processing.
The present invention through conduit aortic valve, by setting at least one on the outer wall of valve frame 1 from the outer wall of valve frame 1
Outward location division 4, because the location division 4 has towards inflow end 11 and outward free end 41, therefore
While the outflow end 12 of valve frame 1 is fixed on human aortic annulus position, location division 4 can be located and fixed within human body actively
Tissue around arteries and veins annulus.Work as heart contraction, blood give pressure from valve to ventricle direction when, except valve frame 1 and blood vessel
Outside the radial support power of circumferencial direction, the effect between the free end 41 of location division 4 and its hetero-organization also blocks valve to ventricle
The risk of interior motion.
Further, since the free end 41 of location division 4 is set towards end 11 is flowed into, and when valve discharges from induction system, valve
The inflow end 11 of frame 1 is discharged in advance, and outflow end 12 is still retained in the conduit of induction system with compressive state；When valve release
Position is inaccurate so as to need to reclaim during valve, valve can be driven to be re-compressed simultaneously to outflow end 12 from flowing into end 11 by conduit
Load in induction system, so as to realize resetting and recovery of the valve in implantation process.
Particularly, with said structure through conduit aortic valve can be using common induction system can be achieved pair
The conveying and positioning of valve, it need not increase induction system conduit without setting the structural member of complexity in induction system
Diameter, so as to possess preferable operation technique.
In the present invention, in order to ensure valve is more accurately positioned, it can be embedded in the end of the free end 41 of location division 4 aobvious
Image device 6 (as shown in Figure 10)；Wherein, developing apparatus 6 can be embedded in the end of 4 free end of location division 41 circle, three
The developing materials such as angular, quadrangle are constituted, and developing material can use Pt, Ta or other materials.In the free end 41 of location division 4
End is embedded developing apparatus 6, is conducive to the position for helping doctor to determine the free end 41 of location division 4 in valve implantation process, so that
The auxiliary positioning of location division 4 is better achieved.
In addition, preferably being conveyed for the ease of induction system to valve, one can be set in the outflow end 12 of valve frame 1
It is used for the fixed part 8 fixed with induction system above；Do not make strict limitation to the concrete structure of fixed part 8, if can with it is defeated
System corresponding component is sent to coordinate, consequently facilitating valve frame 1 to be locked in the catheter interior of induction system in course of conveying；Can
With understanding, fixed part 8 be able to should depart from when valve discharges from conduit, from without influenceing the release of valve.Specifically,
As shown in figure 11, fixed part 8 for example could be arranged to annulus；Do not make strict limitation to the setting quantity of fixed part 8, for example can be with
Three are set to, three fixed parts 8 can be distributed on the circumferencial direction of valve frame 1.
In the present invention, animal pericardium material or novel artificial material can be used in leaflet 2；Polyester or the heart can be used in valve skirt 3
Package such as knits at the material.As shown in figure 1, leaflet 2 and valve skirt 3 can be circumferentially fixed on the inwall of valve frame 1 respectively by suture 9；
Wherein, valve skirt 3 may be provided at the inflow end 11 of valve frame 1, and leaflet 2 can be arranged on the top of valve skirt 3, and leaflet 2 can be with addition
It is fixed on by suture 9 on valve skirt 3.
Further, in order to avoid perivalvular leakage problem, as shown in figure 1, sealed skirt 7 can be set in the outside of valve skirt 3, it is close
Envelope skirt 7 is circumferentially provided on the outer wall of valve frame 1；Sealed skirt 7 is soft and thin, fixation of not fitted completely with the outer surface of valve frame 1, in valve
The gap easily pressed close to and blocked between valve frame 1 and annulus after film implantation, so as to realize the purpose for reducing perivalvular leakage, its material may be selected
Beneficial to being organized in the material that grows thereon.
The present invention's can be discharged and determined with balloon expandable mode and self-inflated expansion pattern through conduit aortic valve
Position；Preferably self-inflated expansion pattern.When being conveyed using conventional induction system through conduit aortic valve, pass through valve frame 1
Radial contraction make valve compression is fitted into the conduit of induction system, entrance internal specified location after, pass through the footpath of valve frame 1
Valve is set to be positioned in human aortic annulus to expansion, while location division 4 is positioned at the tissue around human aortic annulus
On, so as to prevent valve from being slided to ventricle well.In addition, being realized through conduit aortic valve for the present invention was implanted into
The resetting and recovery of journey, and it is capable of the induction system of mating structure simplification, possess preferable operation technique, be conducive to
Actual promotion and application.
Finally it should be noted that：Various embodiments above is merely illustrative of the technical solution of the present invention, rather than its limitations；To the greatest extent
The present invention is described in detail with reference to foregoing embodiments for pipe, it will be understood by those within the art that：Its according to
The technical scheme described in foregoing embodiments can so be modified, or which part or all technical characteristic are entered
Row equivalent substitution；And these modifications or replacement, the essence of appropriate technical solution is departed from various embodiments of the present invention technology
The scope of scheme.
Claims (10)
1. one kind is through conduit aortic valve, it is characterised in that including valve frame, leaflet and valve skirt, the leaflet and valve skirt difference
It is arranged on the valve frame,
The valve frame radial contraction and can be expanded and with end and outflow end is flowed into, provided with extremely on the outer wall of the valve frame
A few outward location division of outer wall from the valve frame, one end of the location division is fixed on the outer wall of the valve frame
On, the other end of the location division is the free end that end is flowed into towards the valve frame.
2. it is according to claim 1 through conduit aortic valve, it is characterised in that the valve frame flows into the radial support at end
Power is more than the radial support power of outflow end.
3. it is according to claim 1 or 2 through conduit aortic valve, it is characterised in that the valve frame is by multiple four sides
The tubular frame that shape unit and multiple hexagonal cells are constituted.
4. it is according to claim 1 through conduit aortic valve, it is characterised in that the location division is in linear, V-arrangement or U
Shape.
5. according to claim 1 or 4 through conduit aortic valve, it is characterised in that in the location division free end
End is coated with medical flexible material.
6. according to claim 1 or 4 through conduit aortic valve, it is characterised in that the free end of the location division leads to
Connector is crossed to be connected with the valve frame.
7. it is any described through conduit aortic valve according to claim 1 to 6, it is characterised in that the freedom of the location division
Outward amplitude is held for 0.5-2mm, the distance between inflow end of the free end of the location division and the valve frame is 4-
13mm。
8. it is any described through conduit aortic valve according to claim 1 to 6, it is characterised in that free in the location division
The end at end is embedded with developing apparatus.
9. it is any described through conduit aortic valve according to claim 1 to 6, it is characterised in that in the valve frame outflow end
It is used for the fixed part with induction system fixation provided with more than one.
10. it is any described through conduit aortic valve according to claim 1 to 6, it is characterised in that in the outside of the valve skirt
Provided with sealed skirt, the sealed skirt is circumferentially provided on the outer wall of the valve frame.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710351059.9A CN107088112A (en) | 2017-05-18 | 2017-05-18 | One kind is through conduit aortic valve |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710351059.9A CN107088112A (en) | 2017-05-18 | 2017-05-18 | One kind is through conduit aortic valve |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107088112A true CN107088112A (en) | 2017-08-25 |
Family
ID=59638586
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710351059.9A Pending CN107088112A (en) | 2017-05-18 | 2017-05-18 | One kind is through conduit aortic valve |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107088112A (en) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107928841A (en) * | 2017-11-27 | 2018-04-20 | 上海形状记忆合金材料有限公司 | A kind of split type aortic valve stent component |
| CN108542554A (en) * | 2018-03-05 | 2018-09-18 | 沛嘉医疗科技(苏州)有限公司 | Through catheter heart valves holder |
| CN108904101A (en) * | 2018-06-29 | 2018-11-30 | 金仕生物科技（常熟）有限公司 | Intervene valve component, the fixed device of intervention valve and its application |
| CN109124829A (en) * | 2018-06-29 | 2019-01-04 | 金仕生物科技（常熟）有限公司 | It is a kind of through conduit aortic valve and preparation method thereof |
| CN109549755A (en) * | 2017-09-25 | 2019-04-02 | 先健科技(深圳)有限公司 | Heart valve |
| WO2019128583A1 (en) * | 2017-12-28 | 2019-07-04 | 上海微创心通医疗科技有限公司 | Cardiac valve prosthesis and stent thereof |
| CN109984868A (en) * | 2017-12-30 | 2019-07-09 | 上海微创心通医疗科技有限公司 | Heart valve prosthesis and conveyer |
| WO2022042310A1 (en) * | 2020-08-25 | 2022-03-03 | 北京市普惠生物医学工程有限公司 | Artificial valve and valve delivery system |
| WO2022078525A1 (en) * | 2020-10-12 | 2022-04-21 | 金仕生物科技（常熟）有限公司 | Interventional mitral valve stent |
| CN115414157A (en) * | 2022-11-07 | 2022-12-02 | 广东捍宇医疗科技有限公司 | Valve device and valve device system |
Citations (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101953725A (en) * | 2010-04-19 | 2011-01-26 | 杭州启明医疗器械有限公司 | Artificial valve displacement device and stent |
| CN102036622A (en) * | 2008-03-18 | 2011-04-27 | 麦德托尼克文托技术公司 | Valve suturing and implantation procedures |
| CN102413793A (en) * | 2009-02-25 | 2012-04-11 | 耶拿阀门科技公司 | Stent for positioning and anchoring of valvular prosthesis in implantation site in heart of patient |
| CN103108611A (en) * | 2010-09-10 | 2013-05-15 | 西美蒂斯股份公司 | Valve replacement devices, delivery device for a valve replacement device and method of production of a valve replacement device |
| CN104000672A (en) * | 2013-02-25 | 2014-08-27 | 上海微创医疗器械（集团）有限公司 | Cardiac valve prostheses |
| CN104799974A (en) * | 2015-04-20 | 2015-07-29 | 上海纽脉医疗科技有限公司 | Involvement type prosthetic heart valve stent with barbs and preparation method thereof |
| CN105050542A (en) * | 2012-11-08 | 2015-11-11 | 西美蒂斯股份公司 | Stent seals and methods for sealing an expandable stent |
| CN105496608A (en) * | 2016-01-11 | 2016-04-20 | 北京迈迪顶峰医疗科技有限公司 | Aortic valve device conveyed by catheter |
| CN105662651A (en) * | 2014-12-05 | 2016-06-15 | Nvt股份公司 | Prosthetic heart valve system and delivery system therefor |
| CN205322549U (en) * | 2016-01-11 | 2016-06-22 | 北京迈迪顶峰医疗科技有限公司 | Carry aortic valve valve device through pipe |
| CN105726167A (en) * | 2016-02-02 | 2016-07-06 | 上海纽脉医疗科技有限公司 | Involved artificial heart valve prosthesis |
-
2017
- 2017-05-18 CN CN201710351059.9A patent/CN107088112A/en active Pending
Patent Citations (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102036622A (en) * | 2008-03-18 | 2011-04-27 | 麦德托尼克文托技术公司 | Valve suturing and implantation procedures |
| CN102413793A (en) * | 2009-02-25 | 2012-04-11 | 耶拿阀门科技公司 | Stent for positioning and anchoring of valvular prosthesis in implantation site in heart of patient |
| CN101953725A (en) * | 2010-04-19 | 2011-01-26 | 杭州启明医疗器械有限公司 | Artificial valve displacement device and stent |
| CN103108611A (en) * | 2010-09-10 | 2013-05-15 | 西美蒂斯股份公司 | Valve replacement devices, delivery device for a valve replacement device and method of production of a valve replacement device |
| CN105050542A (en) * | 2012-11-08 | 2015-11-11 | 西美蒂斯股份公司 | Stent seals and methods for sealing an expandable stent |
| CN104000672A (en) * | 2013-02-25 | 2014-08-27 | 上海微创医疗器械（集团）有限公司 | Cardiac valve prostheses |
| CN105662651A (en) * | 2014-12-05 | 2016-06-15 | Nvt股份公司 | Prosthetic heart valve system and delivery system therefor |
| CN104799974A (en) * | 2015-04-20 | 2015-07-29 | 上海纽脉医疗科技有限公司 | Involvement type prosthetic heart valve stent with barbs and preparation method thereof |
| CN105496608A (en) * | 2016-01-11 | 2016-04-20 | 北京迈迪顶峰医疗科技有限公司 | Aortic valve device conveyed by catheter |
| CN205322549U (en) * | 2016-01-11 | 2016-06-22 | 北京迈迪顶峰医疗科技有限公司 | Carry aortic valve valve device through pipe |
| CN105726167A (en) * | 2016-02-02 | 2016-07-06 | 上海纽脉医疗科技有限公司 | Involved artificial heart valve prosthesis |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109549755A (en) * | 2017-09-25 | 2019-04-02 | 先健科技(深圳)有限公司 | Heart valve |
| CN107928841A (en) * | 2017-11-27 | 2018-04-20 | 上海形状记忆合金材料有限公司 | A kind of split type aortic valve stent component |
| CN107928841B (en) * | 2017-11-27 | 2020-07-28 | 上海形状记忆合金材料有限公司 | Split aortic valve bracket assembly |
| WO2019128583A1 (en) * | 2017-12-28 | 2019-07-04 | 上海微创心通医疗科技有限公司 | Cardiac valve prosthesis and stent thereof |
| US11399933B2 (en) | 2017-12-28 | 2022-08-02 | Shanghai Microport Cardioflow Medtech Co., Ltd. | Cardiac valve prosthesis and stent thereof |
| CN109984868A (en) * | 2017-12-30 | 2019-07-09 | 上海微创心通医疗科技有限公司 | Heart valve prosthesis and conveyer |
| CN108542554A (en) * | 2018-03-05 | 2018-09-18 | 沛嘉医疗科技(苏州)有限公司 | Through catheter heart valves holder |
| CN108904101A (en) * | 2018-06-29 | 2018-11-30 | 金仕生物科技（常熟）有限公司 | Intervene valve component, the fixed device of intervention valve and its application |
| CN109124829A (en) * | 2018-06-29 | 2019-01-04 | 金仕生物科技（常熟）有限公司 | It is a kind of through conduit aortic valve and preparation method thereof |
| WO2022042310A1 (en) * | 2020-08-25 | 2022-03-03 | 北京市普惠生物医学工程有限公司 | Artificial valve and valve delivery system |
| WO2022078525A1 (en) * | 2020-10-12 | 2022-04-21 | 金仕生物科技（常熟）有限公司 | Interventional mitral valve stent |
| CN115414157A (en) * | 2022-11-07 | 2022-12-02 | 广东捍宇医疗科技有限公司 | Valve device and valve device system |
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Application publication date: 20170825 |