CN107029181A - Chinese medicine composition, preparation method and application for nodular goiter - Google Patents
Chinese medicine composition, preparation method and application for nodular goiter Download PDFInfo
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- A61K36/88—Liliopsida (monocotyledons)
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Abstract
A kind of Chinese medicine composition for nodular goiter, preparation method and application, External-applicationtraditional traditional Chinese medicinal is set to include selfheal, fritillaria, curcuma zedoary, oyster, sargentodoxa cuneata and insects, oral traditional Chinese medicine composition are set to include white clover herb, oval kumquat root, rhizome of Kirilow Rhodiola, Fermented Soybean, cicada slough, turmeric, selfheal, dried orange peel, great burdock achene, rhizoma cyperi, Rhizoma Sparganii, kelp, berchemia lineata, sword bean and fructus amomi, are set to include selfheal by External-applicationtraditional traditional Chinese medicinal, fritillaria, curcuma zedoary, oyster, sargentodoxa cuneata and insects, oral traditional Chinese medicine composition are set to include white clover herb, oval kumquat root, rhizome of Kirilow Rhodiola, Fermented Soybean, cicada slough, turmeric, selfheal, dried orange peel, great burdock achene, rhizoma cyperi, Rhizoma Sparganii, kelp, berchemia lineata, the absorption of the pharmaceutical compositions of sword bean and fructus amomi, realizes benefiting qi and raising yang, blood circulation promoting competent silt, open strongly fragrant dissipating bind, softening hard masses are subsided a swelling, desinsection is dispelled turbid, the sore that disappears is relieved pain, these drug regimens are caused each efficacy of drugs to produce synergy by the effect of dredging collateral toxin expelling, so as to the goitre of effectively treatment nodositas, therefore are improved the therapeutic effect strumous to nodositas and are not produced side effect.
Description
First, technical field
The present invention relates to a kind of External-applicationtraditional traditional Chinese medicinal, especially a kind of Chinese medicine composition for nodular goiter, system
Preparation Method and application.
2nd, background technology
Nodular goiter, majority has simplex goiter medical history, to late period it is then more form multiple nodules, the incidence of disease compared with
Height, its symptom is mainly shown as that larger nodular goiter can cause pressure symptom, occur expiratory dyspnea, dysphagia and
Hoarseness, existing operative treatment and drug therapy to nodular goiter, operative treatment can be larger to patient's premature labor
Also there is the problem of side effect is larger not to disappear with tubercle, also without a kind of use in wound, the western medicine of existing drug therapy
Chinese medicine composition, preparation method and application in nodular goiter, are caused so as to improve by nodular goiter illness
Expiratory dyspnea, dysphagia and cracked symptom.
Based on existing technical problem, technical characteristic and technique effect, the application technical scheme of the present invention is made.
3rd, the content of the invention
The object of the present invention is a kind of Chinese medicine composition for nodular goiter,
The object of the present invention is a kind of Chinese medicine composition preparation method for nodular goiter and application
The object of the present invention is the application of a kind of Chinese medicine composition for nodular goiter and preparation method.
In order to overcome above-mentioned technical disadvantages, it is an object of the invention to provide a kind of Chinese medicine group for nodular goiter
Compound, preparation method and application, therefore improve the therapeutic effect strumous to nodositas and do not produce side effect.
To reach above-mentioned purpose, the present invention is adopted the technical scheme that：A kind of Chinese medicine group for nodular goiter
Compound,
External-applicationtraditional traditional Chinese medicinal is set to include selfheal, fritillaria, curcuma zedoary, oyster, sargentodoxa cuneata and insects,
Oral traditional Chinese medicine composition be set to include white clover herb, oval kumquat root, rhizome of Kirilow Rhodiola, Fermented Soybean, cicada slough, turmeric, selfheal,
Dried orange peel, great burdock achene, rhizoma cyperi, Rhizoma Sparganii, kelp, berchemia lineata, sword bean and fructus amomi.
Stated in theory of traditional Chinese medical science：In traditional Chinese medicine, nodular goiter belongs to " goiter and tumor " category, its etiology and pathogenesis
It can mainly be summarized as that the stagnation of the circulation of vital energy, phlegm is solidifying, the broad aspect of blood stasis three.The obstruction of the circulation of vital energy of tracing sth. to its source is fallen ill originally for it.Liver is viscus attriguted to wind and wood, is inside posted
Xiang Huo, using blood as this, using gas as use.The emotion of the spleen being anxiety, worry impairing spleen, long-term is angry strongly fragrant angry, loses irritability and is reached in tune, dredges
Dereliction of duty is let out, the dysfunction of the spleen in transport influences the normal defeated cloth of body fluid.Depression and stagnation of QI body fluid is condensed into phlegm, and mental disorder is condensed with the passing of time, in phlegm wet
Raw, functional activity of QI being not smooth, blood vessels are not all right, and stasis is the stasis of blood, and gas, phlegm, the stasis of blood are mutually tied, and follow through up, it is then tubercle to condense neck.Song Yan
With with《Prescriptions for Succouring the Sick goiter and tumor opinion is controlled》In point out：" husband goiter and tumor person more by intemperance of emotions, over-anxiety, into this disease ".It is long
Phase angry strongly fragrant angry or be worried strongly fragrant is considered so that irritability is lost to be reached in bar, functional activity of QI being not smooth and stasis, and body fluid prevalence is unfavorable, the stagnation of the circulation of vital energy and Tianjin
Stop, body fluid cohesion gathers and forms phlegm.Stagnation of the circulation of vital energy phlegm coagulates heap soil or fertilizer over and around the roots and tied in throat, forms goitre and swells, matter is softer, and its growth and decline is often related to feelings will.
Phlegm can block mechanism of qi, and the two influences each other, so foring phlegm coagulates the solidifying pathological change of depressed or stagnation of the circulation of vital energy phlegm.Thyroid Gland Swell
With the passing of time, blood stasis can be formed, and is served vital.《Miscellaneous diseases source stream rhinoceros candle neck disease source stream》:" goiter and tumor person, qi and blood coagulates
Stagnant, year is far-reaching, gradually grows gradually big disease ".Surgery is authentic》Point out that " card of goiter and tumor, non-negative and positive are just depressed swollen, are that the tired blood of the five internal organs is turbid
Dry phlegm-syndrome is turbid to be formed ", therefore principle of reatment is to gather supporing yang qi-regulating, promoting blood circulation and removing obstruction in channels, reducing phlegm and resolving masses altogether, is set by External-applicationtraditional traditional Chinese medicinal
It is set to and includes selfheal, fritillaria, curcuma zedoary, oyster, sargentodoxa cuneata and insects, oral traditional Chinese medicine composition, which is set to include three, disappears
Grass, oval kumquat root, rhizome of Kirilow Rhodiola, Fermented Soybean, cicada slough, turmeric, selfheal, dried orange peel, great burdock achene, rhizoma cyperi, Rhizoma Sparganii, kelp, berchemia lineata,
The absorption of the pharmaceutical compositions of sword bean and fructus amomi, realize benefiting qi and raising yang, blood circulation promoting competent silt, open strongly fragrant dissipating bind, softening hard masses detumescence, desinsection dispel it is turbid,
These drug regimens are caused each efficacy of drugs to produce synergy, so as to effective by the sore that disappears analgesic, the effect of dredging collateral toxin expelling
The goitre of nodositas is treated, therefore improves the therapeutic effect strumous to nodositas and does not produce side effect.
In the technical program, External-applicationtraditional traditional Chinese medicinal is main prescription, and insects are set to monarch drug in a prescription, and sargentodoxa cuneata is set to
Ministerial drug, oyster and selfheal are set to make medicine, and fritillaria and curcuma zedoary are set to adjutant, selfheal contain numerous antitumor activities into
Point, the sour methyl esters of such as tartaric acid, Alecrim has good inhibition to kinds of tumors, the protoplasm of oyster is calcium carbonate chemical combination
Form, the kind superfluous scrofula of the knurl that disappears, dissipating bind power is strong；Sargentodoxa cuneata is promoting blood circulation and removing obstruction in channels, mass dissipating and swelling eliminating；Insects broken stasis of blood is subsided a swelling, and passes through QI invigorating liter
Sun, blood circulation promoting competent silt, open strongly fragrant dissipating bind, infiltration body of gland, scorching detumescence of dispelling, desinsection dispel the turbid, sore that disappears analgesic, diuresis promoting, dredging collateral toxin expelling and
Body of gland is cleared up, the goitre effect treated and improve nodositas is more preferable.
The present invention is devised, a kind of Chinese medicine composition for nodular goiter, according to part by weight,
External-applicationtraditional traditional Chinese medicinal is set to include selfheal 13-17g, fritillaria 9-12g, curcuma zedoary 9-12g, oyster 13-17g, big
Blood rattan 9-12g and insects 8-12g,
Oral traditional Chinese medicine composition is set to include 3-8 parts of white clover herb, 15-20 parts of oval kumquat root, 22-24 parts of rhizome of Kirilow Rhodiola, light beans
3-9 parts of fermented soya beans, salted or other wise, 6-9 parts of cicada slough, 4-8 parts of turmeric, 10-23 parts of selfheal, 18-25 parts of dried orange peel, great burdock achene 8-11
5-14 parts of part, 12-16 parts of rhizoma cyperi, 10-14 parts of Rhizoma Sparganii, 7-10 parts of kelp, 11-23 parts of berchemia lineata, 2-9 parts of sword bean and fructus amomi.
The present invention is devised, according to part by weight,
External-applicationtraditional traditional Chinese medicinal is set to include selfheal 15g, fritillaria 10g, curcuma zedoary 10g, oyster 15g, sargentodoxa cuneata 10g and Qiang
Dung beetle worm 10g,
Oral traditional Chinese medicine composition is set to include 3-8 parts of white clover herb, 15-20 parts of oval kumquat root, 22-24 parts of rhizome of Kirilow Rhodiola, light beans
3-9 parts of fermented soya beans, salted or other wise, 6-9 parts of cicada slough, 4-8 parts of turmeric, 10-23 parts of selfheal, 18-25 parts of dried orange peel, great burdock achene 8-11
5-14 parts of part, 12-16 parts of rhizoma cyperi, 10-14 parts of Rhizoma Sparganii, 7-10 parts of kelp, 11-23 parts of berchemia lineata, 2-9 parts of sword bean and fructus amomi.
The present invention is devised, according to part by weight,
External-applicationtraditional traditional Chinese medicinal is set to include selfheal 16g, fritillaria 10g, curcuma zedoary 12g, oyster 16g, sargentodoxa cuneata 9g and Qiang
Dung beetle worm 9g,
Oral traditional Chinese medicine composition is set to include 7 parts of white clover herb, 16 parts of oval kumquat root, 23 parts of rhizome of Kirilow Rhodiola, 8 parts of Fermented Soybean, cicada
Slough off 9 parts, 4 parts of turmeric, 19 parts of selfheal, 18 parts of dried orange peel, 11 parts of great burdock achene, 15 parts of rhizoma cyperi, 13 parts of Rhizoma Sparganii, kelp
7 parts of 9 parts, 22 parts of berchemia lineata, 9 parts of sword bean and fructus amomi.
The present invention is devised, and a kind of Chinese medicine composition and preparation method for nodular goiter is in treatment nodositas
Application strumous.
The present invention is devised, a kind of preparation method of Chinese medicine composition for nodular goiter, and its step is：
First, selfheal, fritillaria, curcuma zedoary, oyster, sargentodoxa cuneata and insects are ground, 25- is made in selfheal and sargentodoxa cuneata
The particle of 35 mesh, is made fritillaria and curcuma zedoary the particle of 14-16 mesh, oyster and insects purpose particle, is passing through puddler
Selfheal, fritillaria, curcuma zedoary, oyster, sargentodoxa cuneata and insects are mixed, yellow rice wine is added, the middle medicine of pasty state is made,
2nd, 3-8 parts of white clover herb, 15-20 parts of oval kumquat root, 22-24 parts of rhizome of Kirilow Rhodiola, 3-9 parts of Fermented Soybean, 6-9 parts of cicada slough,
4-8 parts of turmeric, 10-23 parts of selfheal, 18-25 parts of dried orange peel, 8-11 parts of great burdock achene, 12-16 parts of rhizoma cyperi, Rhizoma Sparganii 10-
After 5-14 parts of 14 parts, 7-10 parts of kelp, 11-23 parts of berchemia lineata, 2-9 parts of sword bean and fructus amomi remove the gred, add according to part by weight
100：2-10 adds rice vinegar and honey, carries out immersion 40-50 minutes to Chinese medicine composition, then rice vinegar and honey are fallen
Go out, add in 1000ml water, boiled the medicament in 20-50ml.
The property of medicine of component in the prescription of the present invention：
Selfheal：Alias：Wheat head selfheal, iron wire selfheal（Yunnan book series）, Mai Xia is withered, the iron wire summer is withered（The southern regions of the Yunnan Province book on Chinese herbal medicine）, sunset
Sentence, Nedong（This warp）Deng；For herbaceos perennial, creeping rootstock, raw fibrous root on section.Stem is up to 30 centimetres, base portion multi-branched,
Lilac.Calyx is bell, and filigree is slightly flat, and style is very thin, and tip sliver bores shape, excurvation.The nearly flat-top of floral disc.Pyrene is yellowish-brown
Color, the month at florescence 4-6, the fruiting period 7-10 months
Fritillaria：For herbaceos perennial.Its bulb hyoscine.Because its shape is gained the name,《Bencao jizhu》Say：" the poly- shellfish of likeness in form
Son ", therefore named fritillaria can relieving cough and reducing sputum, heat-clearing dissipating bind work(.Alias：Diligent mother, bitter dish, bitter flower, empty grass, medicine are real.
Curcuma zedoary：Bie Cheng Shu medicine, Curcuma Shu, blue or green ginger, evil mind ginger, turmeric, Latin name：Curcuma zedoaria
（Christm.）Rosc., curcuma zedoary is Zingiber, turmeric perennial herb, and this product is zingiberaceous plant zedoary Curcuma
Phaeocaulis Val., Guangxi zedoary Curcuma Kwangsiensis S. G.Lee et C. F. Liang or Wen Yu
Golden Curcuma wenyujin Y.H. Chen et C. Ling dry rhizome.The latter, which practises, claims " Curcuma wenyujin ".Winter cauline leaf is withered
Excavated after withering, clean, steam or boil to the saturating heart, dry or low temperature drying after remove fibrous root and impurity.About 1 meter of plant height；Rhizome cylinder
Shape, meat, fragrance, faint yellow or white as tool camphor；Root is elongated or end enlarges into root tuber, cultivation or wild under Lin Yin,
Promoting qi circulation and relieving pain, product dissipating bind, dissipating blood stasis with potent drugs effect can be controlled.
Oyster：It is seashell.In subtropical zone, the cultivation of the coastal all suitable oyster in the torrid zone, China's distribution is very wide, green North gets duck
River, south is coastal all to produce oyster to Hainan Island.Oyster is that software has shell, the animal of micropredation, and salt-fresh water, which has a common boundary, produces particularly fertilizer
It is beautiful.[1]It is mollusk, there are two shells, one small and flat, another is big and swells, the surface irregularity of shell.Meat is for food
With oyster sauce can be obtained through refining again.Meat, shell, oil can all be used as medicine, and also cry oyster or oyster.
Sargentodoxa cuneata：Practise and claim Sargent gloryvine, also known as blood rattan, red skin rattan etc., sargentodoxa cuneata is fallen leaves, bejuco；Stem bronzing；
Compound leaf three goes out, alternate；The different strain of flower unisexuality, radiation symmetric, petal 6 is minimum, calyx 6, petal-shaped；Fruit is aggregate fruit, by multiple
Meat small berries are constituted.
Insects：Dung beetle, dung gram dung beetle, dorbeetle are commonly called as, is a paraphyletic group under coleoptera Scarabaeoidea.Body is black
Color or dark brown, big-and-middle-sized insect.Dung beetle can be positioned using moonlight polarization phenomena, and the aerial milky way navigation of ether, with
Help takes food.There is certain phototaxis.
White clover herb：For legume white cloverTrifolium repensL. herb.It is distributed in northeast, North China, river
Soviet Union, Guizhou, Yunnan.With heat-clearing, cool blood, the effect of calming heart.It is usually used in epilepsy, hemorrhoid hemorrhage, scleroma lump.
Oval kumquat root：For rutaceae kumquat and the root of golden bullet.
Rhizome of Kirilow Rhodiola：Perennial herb, high 30~70cm.Rhizome is wooden, tuberosity, has red eye, one is born thereon
Or many stems.Usual not branch, four prismatics；By the sugared not plump shape pubescence of white and mixed raw tool section pubescence.Leaf is to life, narrow or wealthy ovum
Shape, long 2.5~6cm, wide 1.4~3.8cm, the sharp point of tip is dilute blunt, base portion wedge shape, stockless, or the gradually narrow false handle into tool wing, edge
Have knuckle-tooth, above close quilt or dredge by strigose, below it is close by purple gland point, especially have the not plump short bristle of sugar on arteries and veins.
Fermented Soybean：For the fermentation processing product of the mature seed of legume soybean, its taste bitter and cold, with inducing diaphoresis, relieving restlessness,
The effect of Xuan Yu, removing toxic substances.For typhoid fever pyreticosis, fever and chills, headache is irritated, uncomfortable in chest.
Cicada slough：Its holotype is hollow like cicada, slightly bent.It is about 100px, wide about 50px.Surface yellowish-brown, it is translucent, have
Gloss.There is 1 pair of filiform antenna on head, has broken more, and compound eye is protruded, and neck tip is protruded, and tone is flourishing, and upper lip is wide short, lower lip
Extend into tubulose.The chest back side is in cross sliver, and breach inward curl, back both sides has 2 pairs of winglet；The outside of belly has 3 pairs of foot,
By yellowish-brown fine, soft fur.Belly blunt circle, 9 is saved totally.Body is light, hollow, frangible.Odorless, it is lightly seasoned.Function：Dispelling wind-heat, promoting eruption relieving sore-throat,
Removing nebula for improving eyesight, expelling wind and relieving convulsion.
Turmeric：Also known as：Root tuber of aromatic turmeric, tripod perfume, milli life, yellow ginger etc..
Turmeric Musales, Zingiber, turmeric herbaceos perennial, 1~1.5m of plant height, rhizome is very flourishing, and root is sturdy, end
Expand in root tuber at end；Blade Long Circle or ellipse, leaf top are short tapering；Bract is avette or Long Circle, and light green, top is blunt,
Corolla is faint yellow；Florescence August, turmeric energy promoting the circulation of qi broken stasis of blood is inducing meastruation to relieve menalgia.Cure mainly chest and abdomen swelling and pain, shoulder arm numbness pain, it is pained unbearably, production
Bitterly, sore tinea is initial, irregular menstruation, amenorrhoea, traumatic injury for blood afterwards.
Dried orange peel：For rutaceae orangeCitrus reticulata BlancoAnd its drying and ripening fruit of variety
Skin.
Great burdock achene：For composite family biennial herb plant burdock（Scientific name：Arctium lappa L.）Dry mature fruit.
It is slightly flat in long inverted ovoid, microbend, long 5~7mm, wide 2~3mm.Surface taupe, band atropurpureus spot, there is several vertical ribs,
Generally middle 1~2 more apparent.Top blunt circle, slightly wider, top surface has annulus, centre tool point-like style vestiges；Base portion is slightly narrow,
Dough color is thin.Pericarp is harder, and cotyledon 2, yellowish white is High oleic.Micro-pungent after odorless, bitter and slightly numb tongue.Autumn fruit into
Infructescence is harvested when ripe, is dried, fruit is laid, impurity is removed, then dry.Raw to use or fry use, the used time smashs to pieces.With dispelling wind and heat from the body,
The effect of facilitaing lung promoting eruption, relieving sore-throat dissipating bind, removing toxicity for detumescence.Belong to wind-heat-dispersing medicinal in diaphoretic medicine.Modern study, great burdock achene also can use
In preventing and treating diabetic nephropathy；Arctium lappa fruit Arctigenin through hydrolysis generation containing arctiin has active anticancer.
Rhizoma cyperi：For the dry rhizome of sedge nutgrass flatsedge.Autumn excavates, and sing the hair palpus, puts and slightly boils or steam in boiling water thoroughly
After dry, or directly dry after burning.
Rhizoma Sparganii：For Sparganiaceae plant rhizoma scirpiSparganium stoloni erum,Buch.-Ham. dried pieces
Stem.Spring winter to next year excavates, and cleans, prunes crust, dry.It is distributed in northeast, the Yellow River, basin, the middle and lower reach of Yangtze River and Tibet.
With blood-breaking, effect of Xiao Ji Zhi Tong.For abdominal mass lump in the abdomen, dysmenorrhoea, blood stasis closed, chest impediment and cardialgia, dyspepsia distending pain.
Kelp：Also known as " black dish ", " goose slaps dish ", " five palm dish " etc..Phaeophyceae, Alariaceae.Sporinite is large-scale, brown, leather
Matter, high 30-100cm, leaflet piece, shank, holdfast, holdfast rhizoid shape.The V shape branch of rhizoid two, shank cylindrical shape, nearly leaf
Piece portion is gradually flat, and blade both sides pinniform or coverts shape branch, middle part are slightly thick, intercalary growth, long 1-12cm, thick 3-7mm, rough sawn tooth
Leaf margin.Zoospore is born in blade two sides.Have and do not wait the alternation of generations significantly.It is grown in the ocean of temperate zone.
Berchemia lineata：Tender core yellow green, it is close by pubescence.Because of the brown chalybeate of bolt hair of the kind root, xylem color is yellow seemingly
Gold, therefore named berchemia lineata.General hill, coppice, roadside, hillside fields and the hills for being grown in low altitude area.Medicinal material berchemia lineata is Rhamnaceae
Plant berchemia lineata and the stem rattan of congener littleleaf supplejackherba or root.Come from《The south of the Five Ridges is gathered medicinal herbs record》, It is the end of summer, just turning into autumn, extract before pregnant flower bud
Young stem and leaf, removes impurity, and chopping or is dried at using fresh herb；Root is adopted after autumn, and using fresh herb or section are dried and be used as medicine.With subdhing swelling and detoxicating, hemostasis
The effects such as analgesia, dispelling wind and eliminating dampness.
Sword bean：The cultivation subspecies of pulse family Canavalia, annual prehensile herbaceous plant.It is also the kind of legume sword bean
Son.Autumn, the ripe pod of winter harvesting, dry, strip seed standby；Or autumn harvesting green bean fruit using fresh herb.The drying and ripening of sword bean
Seed, alias Sword Jackbean Seed, big sword bean.
Fructus amomi：Also known as：Fructus Amomi, Changtai fructus（Fujian）, also known as cardamom, perennial herb.It is the torrid zone and Asia heat
Fruits and seedses with zingiberaceous plant, are the conventional aromaticity medicinal materials simply of the traditional Chinese medical science.1.5-3 meters of plant height, stem is scattered；Rhizome is crawled
By brown film quality scale on crawl ground, section.Rhizome is sturdy, brownish red.3 valves of seed group point, every 5~9 pieces of valve seed, seed smell
Fragrance and it is high strong, slightly peppery as spices, its taste is like camphor tree.
In the technical program, selfheal, fritillaria, curcuma zedoary, oyster, sargentodoxa cuneata and insects are important technical characteristic,
Chinese medicine composition for nodular goiter, in the technical field of preparation method and application, with novelty, it is creative and
Practicality, the term in the technical program is all that can be explained and be understood with patent document in the art.
4th, embodiment
According to guidelines for examination, such as " having ", "comprising" and " comprising " term used in the present invention should be understood to not
Allot the presence or addition of one or more of the other element or its combination.
In the description of the invention, it is necessary to explanation, term " " center ", " on ", " under ", "left", "right", " vertical ",
The orientation or position relationship of the instruction such as " level ", " interior ", " outer " are the orientation or position relationship of general expression, are for only for ease of
The description present invention and simplified description, rather than indicate or imply that the device or element of meaning must have specific orientation, Yi Te
Fixed azimuth configuration and operation, therefore be not considered as limiting the invention.In addition, term " first ", " second ", " the 3rd "
It is only used for describing purpose, and it is not intended that indicating or implying relative importance.
In the description of the invention, it is necessary to illustrate, unless otherwise clearly defined and limited, term " installation ", " phase
Even ", " connection " should be interpreted broadly, for example, it may be being fixedly connected or being detachably connected, or be integrally connected；Can
To be mechanical connection or electrical connection；Can be joined directly together, can also be indirectly connected to by intermediary, Ke Yishi
The connection of two element internals.For the ordinary skill in the art, with concrete condition above-mentioned term can be understood at this
Concrete meaning in invention.
As long as in addition, technical characteristic involved in invention described below different embodiments non-structure each other
It can just be combined with each other into conflict.
Below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely retouched
State, it is clear that described embodiment is only a part of embodiment of the invention, rather than whole embodiments.Based in the present invention
Embodiment, the every other embodiment that those of ordinary skill in the art are obtained under the premise of creative work is not made,
Belong to the scope of protection of the invention.
A kind of Chinese medicine composition for nodular goiter, one embodiment of the invention, illustrates this reality
Example is applied, according to part by weight,
External-applicationtraditional traditional Chinese medicinal is set to include selfheal 13-17g, fritillaria 9-12g, curcuma zedoary 9-12g, oyster 13-17g, big
Blood rattan 9-12g and insects 8-12g,
Oral traditional Chinese medicine composition is set to include 3-8 parts of white clover herb, 15-20 parts of oval kumquat root, 22-24 parts of rhizome of Kirilow Rhodiola, light beans
3-9 parts of fermented soya beans, salted or other wise, 6-9 parts of cicada slough, 4-8 parts of turmeric, 10-23 parts of selfheal, 18-25 parts of dried orange peel, great burdock achene 8-11
5-14 parts of part, 12-16 parts of rhizoma cyperi, 10-14 parts of Rhizoma Sparganii, 7-10 parts of kelp, 11-23 parts of berchemia lineata, 2-9 parts of sword bean and fructus amomi.
Selfheal 13-17g, fritillaria 9-12g, curcuma zedoary 9-12g, oyster 13-17g, sargentodoxa cuneata 9-12g and insects 8-
12g distinguish grind into powder thing, by yellow rice wine the powder thing of selfheal, the powder thing of fritillaria, the powder thing of curcuma zedoary, oyster powder
The powder thing of last thing, the powder thing of sargentodoxa cuneata and insects is mixed into the middle medicine of pasty state, according to twice daily in pasty state
Herbal medicines for external use is in goitre tubercle, and the external application time is at least 45 minutes.
3-8 parts of white clover herb, 15-20 parts of oval kumquat root, 22-24 parts of rhizome of Kirilow Rhodiola, 3-9 parts of Fermented Soybean, 6-9 parts of cicada slough,
4-8 parts of turmeric, 10-23 parts of selfheal, 18-25 parts of dried orange peel, 8-11 parts of great burdock achene, 12-16 parts of rhizoma cyperi, Rhizoma Sparganii 10-
5-14 parts of 14 parts, 7-10 parts of kelp, 11-23 parts of berchemia lineata, 2-9 parts of sword bean and fructus amomi remove residue after being crushed, and are adding
Rice vinegar and honey carry out immersion 40-50 minutes, add in 1000ml water, are boiled and taken after 20-50ml, sooner or later daily
Individual once it 15 days is a course for the treatment of continuously to attach and take, and must be disabled 30 days after three courses for the treatment of for oral administration.
The preparation method of a kind of Chinese medicine composition for nodular goiter, with reference to embodiment, to the present invention
Further describe, following examples are intended to illustrate invention rather than limitation of the invention further.Its step is：
First, selfheal, fritillaria, curcuma zedoary, oyster, sargentodoxa cuneata and insects are ground, 25- is made in selfheal and sargentodoxa cuneata
The particle of 35 mesh, is made fritillaria and curcuma zedoary the particle of 14-16 mesh, oyster and insects purpose particle, is passing through puddler
Selfheal, fritillaria, curcuma zedoary, oyster, sargentodoxa cuneata and insects are mixed, yellow rice wine is added, the middle medicine of pasty state is made,
2nd, 3-8 parts of white clover herb, 15-20 parts of oval kumquat root, 22-24 parts of rhizome of Kirilow Rhodiola, 3-9 parts of Fermented Soybean, 6-9 parts of cicada slough,
4-8 parts of turmeric, 10-23 parts of selfheal, 18-25 parts of dried orange peel, 8-11 parts of great burdock achene, 12-16 parts of rhizoma cyperi, Rhizoma Sparganii 10-
After 5-14 parts of 14 parts, 7-10 parts of kelp, 11-23 parts of berchemia lineata, 2-9 parts of sword bean and fructus amomi remove the gred, add according to part by weight
100：2-10 adds rice vinegar and honey, carries out immersion 40-50 minutes to Chinese medicine composition, then rice vinegar and honey are fallen
Go out, add in 1000ml water, boiled the medicament in 20-50ml.
Below in conjunction with clinical test and model case, the present invention is further described.
Clinical test, clinical data have been carried out in Hospital Attached to Taishan Medical College；
General information：Accept nodular goiter patient 100, wherein male 30, women 70, age for medical treatment altogether
23-69 Sui, average age 40 years old, the course of disease is most long 8 years, most short half a year.
Treatment method：According to a kind for the treatment of of one embodiment of the Chinese medicine composition for nodular goiter
Method,
Curative effect judging standard：
Cure：The symptom of thyroid gland swelling is wholly absent, because the other symptoms that nodular goiter triggers also disappear；
Effectively：Thyroid gland swelling position substantially diminishes, because the other symptoms that nodular goiter triggers disappear；
Adverse reaction：There are the symptoms such as stomachache, dizziness, nausea and vomiting after medication.
Treatment results：96, effective 3, invalid 1 are cured in treatment through the 2-4 course for the treatment of, 100 patients
Example, cure rate 96%, total effective rate 99%, determined curative effect is uneasy to recur, and patient does not occur malaise symptoms in therapeutic process.
Model case 1
Lee, female, 60 years old.Right neck Silent Neuritis enclosed mass 5 years, no hyperthyroidism symptom.Color ultrasound is pointed out：Thyroid gland lobus lateralis sinister is shown in
0.1cm × 0.2cm no echo areas, visible 2 no echo areas of lobus lateralis dexter, size is respectively 2.7cm × 1.6cm, 0.3cm
×0.5cm.Pole has a size to be 2.0cm × 3.0cm or so dark red color lump under right thyroid, and quality is slightly hard, and coating is completeer
It is whole, it is diagnosed as nodular goiter.Patient refuses operative treatment, and drug therapy of the present invention, three courses for the treatment of are used after being introduced
Enclosed mass is to see diminution afterwards, and B is super after two courses for the treatment of of continual cure checks that lump disappears, and follow-up is not recurred for 1 year.
Model case 2
Zhang, female, 26 years old, readme throat lump 2 years, with foreign body in pharynx sense, feelings will is aggravated when unsuccessful.Look into poke,
Diffuse symmetrical, feel turgor, matter soft light is slided, no tenderness；When have uncomfortable in chest, sighing frequently；Tongue is red, and tongue is thin white, veins string.It is diagnosed as knot
Section property goitre.After one course for the treatment of of drug therapy of the present invention, lump is shown in diminution, and foreign body in pharynx sense mitigates, continual cure two
Pharyngeal foreign body sensation disappears after the individual course for the treatment of, and B is super to check that lump disappears, and thyroid gland recovers normal, and follow-up is not recurred for 2 years.
Model case 2
Summer, man 44 years old, by B ultrasound it can be found that there is two 1 × 3cm tubercle at thyroid gland.Take the present embodiment one
The course for the treatment of.Patient respiratory is smooth than before, and malaise symptoms mitigate；Continue taking the two courses, disappearance of being swollen and ache at patient's thyroid gland,
Malaise symptoms substantially disappear, and patient's recovery from illness, Effect of follow-up visit by telephone does not recur.
Zhang, man 50 years old, through ultrasound diagnosis, right thyroid has the .0cm of 1 .5 × 2 tubercle, to basic living
Do not influence, it is all to be never effectively treated, feel that throat is uncomfortable in the recent period, and with pain, unsmooth breath,
The problems such as diet is not smooth, and neck swelling is more and more severe, ultrasound diagnosis, right thyroid has the .6cm's of 3 .5 × 2
Tubercle, takes two courses for the treatment of of the present embodiment.Patient respiratory is smooth than before, and malaise symptoms mitigate；Continue to take a course for the treatment of,
Swollen and ache at patient's thyroid gland disappearance, malaise symptoms substantially disappear, patient's recovery from illness, Effect of follow-up visit by telephone does not recur.
Second embodiment of the present invention, illustrates the present embodiment, according to part by weight,
External-applicationtraditional traditional Chinese medicinal is set to include selfheal 15g, fritillaria 10g, curcuma zedoary 10g, oyster 15g, sargentodoxa cuneata 10g and Qiang
Dung beetle worm 10g,
Oral traditional Chinese medicine composition is set to include 3-8 parts of white clover herb, 15-20 parts of oval kumquat root, 22-24 parts of rhizome of Kirilow Rhodiola, light beans
3-9 parts of fermented soya beans, salted or other wise, 6-9 parts of cicada slough, 4-8 parts of turmeric, 10-23 parts of selfheal, 18-25 parts of dried orange peel, great burdock achene 8-11
5-14 parts of part, 12-16 parts of rhizoma cyperi, 10-14 parts of Rhizoma Sparganii, 7-10 parts of kelp, 11-23 parts of berchemia lineata, 2-9 parts of sword bean and fructus amomi.
The prescription of second embodiment of the present invention is preferred.
The 3rd embodiment of the present invention, illustrates the present embodiment, according to part by weight,
External-applicationtraditional traditional Chinese medicinal is set to include selfheal 13g, fritillaria 9g, curcuma zedoary 9g, oyster 13g, sargentodoxa cuneata 9g and dung beetle
Worm 8g,
Oral traditional Chinese medicine composition be set to include 8 parts of white clover herb, 20 parts of oval kumquat root, 24 parts of rhizome of Kirilow Rhodiola, 9 parts of Fermented Soybean,
9 parts of cicada slough, 8 parts of turmeric, 23 parts of selfheal, 25 parts of dried orange peel, 11 parts of great burdock achene, 16 parts of rhizoma cyperi, 14 parts of Rhizoma Sparganii,
14 parts of 10 parts of kelp, 23 parts of berchemia lineata, 9 parts of sword bean and fructus amomi.
The 4th embodiment of the present invention, illustrates the present embodiment, according to part by weight,
External-applicationtraditional traditional Chinese medicinal is set to include selfheal 17g, fritillaria 12g, curcuma zedoary 12g, oyster 17g, sargentodoxa cuneata 12g and Qiang
Dung beetle worm 12g,
Oral traditional Chinese medicine composition is set to include 8 parts of white clover herb, 20 parts of oval kumquat root, 24 parts of rhizome of Kirilow Rhodiola, 9 parts of Fermented Soybean, cicada
Slough off 9 parts, 8 parts of turmeric, 23 parts of selfheal, 25 parts of dried orange peel, 11 parts of great burdock achene, 16 parts of rhizoma cyperi, 14 parts of Rhizoma Sparganii, elder brother
14 parts of 10 parts of cloth, 23 parts of berchemia lineata, 9 parts of sword bean and fructus amomi.
The 5th embodiment of the present invention, illustrates the present embodiment, according to part by weight,
External-applicationtraditional traditional Chinese medicinal is set to include selfheal 15g, fritillaria 10g, curcuma zedoary 10g, oyster 14g, sargentodoxa cuneata 10g and Qiang
Dung beetle worm 10g,
Oral traditional Chinese medicine composition is set to include 5 parts of white clover herb, 17 parts of oval kumquat root, 23 parts of rhizome of Kirilow Rhodiola, 6 parts of Fermented Soybean, cicada
Slough off 7 parts, 6 parts of turmeric, 16 parts of selfheal, 21 parts of dried orange peel, 9 parts of great burdock achene, 14 parts of rhizoma cyperi, 12 parts of Rhizoma Sparganii, kelp
10 parts of 8 parts, 17 parts of berchemia lineata, 6 parts of sword bean and fructus amomi.
The 6th embodiment of the present invention, illustrates the present embodiment, according to part by weight,
External-applicationtraditional traditional Chinese medicinal is set to include selfheal 16g, fritillaria 10g, curcuma zedoary 12g, oyster 16g, sargentodoxa cuneata 9g and Qiang
Dung beetle worm 9g,
Oral traditional Chinese medicine composition is set to include 7 parts of white clover herb, 16 parts of oval kumquat root, 23 parts of rhizome of Kirilow Rhodiola, 8 parts of Fermented Soybean, cicada
Slough off 9 parts, 4 parts of turmeric, 19 parts of selfheal, 18 parts of dried orange peel, 11 parts of great burdock achene, 15 parts of rhizoma cyperi, 13 parts of Rhizoma Sparganii, kelp
7 parts of 9 parts, 22 parts of berchemia lineata, 9 parts of sword bean and fructus amomi.
The present invention second and third, four, five and six embodiments be based on one embodiment of the present invention, it is clinical
Result of the test shows, the prescription of the 6th embodiment of the invention, to the treatment age for 60-65 Sui with nodositas thyroid gland
Swollen patient, the effect to treatment nodular goiter is best, while also having improved effect to diabetes, to treatment glycosuria
The nodular goiter effect that sufferer has is best.
A kind of application of embodiment of Chinese medicine composition in treatment nodular goiter.
The present invention has lower feature：
1st, it is set to include selfheal, fritillaria, curcuma zedoary, oyster, sargentodoxa cuneata and insects by External-applicationtraditional traditional Chinese medicinal, takes orally
Chinese medicine composition is set to include white clover herb, oval kumquat root, rhizome of Kirilow Rhodiola, Fermented Soybean, cicada slough, turmeric, selfheal, dried orange peel, burdock
Son, rhizoma cyperi, Rhizoma Sparganii, kelp, berchemia lineata, the absorption of the pharmaceutical compositions of sword bean and fructus amomi, realize benefiting qi and raising yang, blood circulation promoting competent silt, open
These drug regimens are caused each medicine work(by strongly fragrant dissipating bind, softening hard masses are subsided a swelling, desinsection the is dispelled turbid, sore that disappears analgesic, the effect of dredging collateral toxin expelling
Effect produces synergy, so as to the goitre of effectively treatment nodositas, therefore improves the goitre to nodositas
Therapeutic effect and do not produce side effect.
2nd, prescription of the invention is by external application and mode for oral administration, meets and gathers supporing yang qi-regulating, promoting blood circulation and removing obstruction in channels, resolving sputum altogether and dissipate
The base therapy method of knot.
3rd, by the effective ingredient of selfheal, fritillaria, curcuma zedoary, oyster, sargentodoxa cuneata and insects in caking strumous
Infiltration and white clover herb, oval kumquat root, rhizome of Kirilow Rhodiola, Fermented Soybean, cicada slough, turmeric, selfheal, dried orange peel, great burdock achene, rhizoma cyperi, Rhizoma Sparganii, elder brother
Cloth, berchemia lineata, the absorption of the pharmaceutical compositions of sword bean and fructus amomi, during treating to the hepatic and renal function of patient, blood, urine, excrement finger
Mark is tracked chemical examination, has not significant impact.
4th, External-applicationtraditional traditional Chinese medicinal is set to include based on selfheal, fritillaria, curcuma zedoary, oyster, sargentodoxa cuneata and insects
Want prescription, it is withered that oral traditional Chinese medicine composition is set to include white clover herb, oval kumquat root, rhizome of Kirilow Rhodiola, Fermented Soybean, cicada slough, turmeric, summer
Grass, dried orange peel, great burdock achene, rhizoma cyperi, Rhizoma Sparganii, kelp, berchemia lineata, sword bean and fructus amomi assisted prescription, by the combination of the two, are improved
To the treatment rate strumous of nodositas,
5th, due to devising technical characteristic of the invention, the effect of set in the independent of technical characteristic and each other passes through
Experiment shows that property indices of the invention are at least 1.7 times for existing property indices, have very by assessing
Good market value.
It is also other it is same or like with selfheal, fritillaria, curcuma zedoary, oyster, sargentodoxa cuneata and insects as in medicine
All it is one of embodiments of the invention, and each technical characteristic of embodiment described above can be combined arbitrarily, be full
The requirement of sufficient Patent Law, patent regulation and guidelines for examination, it is no longer all to each technical characteristic in above-described embodiment can
The embodiment of the combination of energy is all described.
Above-described embodiment be it is provided by the present invention for the Chinese medicine composition of nodular goiter, preparation method and
Application a kind of way of realization, according to scheme provided by the present invention other deformation, increase or reduce composition therein or
Step, or the present invention is used for other technical fields close with the present invention, belong to protection scope of the present invention.
Claims (6)
1. a kind of Chinese medicine composition for nodular goiter, it is characterized in that：
External-applicationtraditional traditional Chinese medicinal is set to include selfheal, fritillaria, curcuma zedoary, oyster, sargentodoxa cuneata and insects,
Oral traditional Chinese medicine composition be set to include white clover herb, oval kumquat root, rhizome of Kirilow Rhodiola, Fermented Soybean, cicada slough, turmeric, selfheal,
Dried orange peel, great burdock achene, rhizoma cyperi, Rhizoma Sparganii, kelp, berchemia lineata, sword bean and fructus amomi.
2. the Chinese medicine composition according to claim 1 for nodular goiter, it is characterized in that：According to weight ratio
Example,
External-applicationtraditional traditional Chinese medicinal is set to include selfheal 13-17g, fritillaria 9-12g, curcuma zedoary 9-12g, oyster 13-17g, big
Blood rattan 9-12g and insects 8-12g,
Oral traditional Chinese medicine composition is set to include 3-8 parts of white clover herb, 15-20 parts of oval kumquat root, 22-24 parts of rhizome of Kirilow Rhodiola, light beans
3-9 parts of fermented soya beans, salted or other wise, 6-9 parts of cicada slough, 4-8 parts of turmeric, 10-23 parts of selfheal, 18-25 parts of dried orange peel, great burdock achene 8-11
5-14 parts of part, 12-16 parts of rhizoma cyperi, 10-14 parts of Rhizoma Sparganii, 7-10 parts of kelp, 11-23 parts of berchemia lineata, 2-9 parts of sword bean and fructus amomi.
3. the Chinese medicine composition according to claim 2 for nodular goiter, it is characterized in that：According to weight ratio
Example,
External-applicationtraditional traditional Chinese medicinal is set to include selfheal 15g, fritillaria 10g, curcuma zedoary 10g, oyster 15g, sargentodoxa cuneata 10g and Qiang
Dung beetle worm 10g,
Oral traditional Chinese medicine composition is set to include 3-8 parts of white clover herb, 15-20 parts of oval kumquat root, 22-24 parts of rhizome of Kirilow Rhodiola, light beans
3-9 parts of fermented soya beans, salted or other wise, 6-9 parts of cicada slough, 4-8 parts of turmeric, 10-23 parts of selfheal, 18-25 parts of dried orange peel, great burdock achene 8-11
5-14 parts of part, 12-16 parts of rhizoma cyperi, 10-14 parts of Rhizoma Sparganii, 7-10 parts of kelp, 11-23 parts of berchemia lineata, 2-9 parts of sword bean and fructus amomi.
4. the Chinese medicine composition according to claim 2 for nodular goiter, it is characterized in that：According to weight ratio
Example,
External-applicationtraditional traditional Chinese medicinal is set to include selfheal 16g, fritillaria 10g, curcuma zedoary 12g, oyster 16g, sargentodoxa cuneata 9g and Qiang
Dung beetle worm 9g,
Oral traditional Chinese medicine composition is set to include 7 parts of white clover herb, 16 parts of oval kumquat root, 23 parts of rhizome of Kirilow Rhodiola, 8 parts of Fermented Soybean, cicada
Slough off 9 parts, 4 parts of turmeric, 19 parts of selfheal, 18 parts of dried orange peel, 11 parts of great burdock achene, 15 parts of rhizoma cyperi, 13 parts of Rhizoma Sparganii, kelp
7 parts of 9 parts, 22 parts of berchemia lineata, 9 parts of sword bean and fructus amomi.
5. the preparation method of the Chinese medicine composition according to claim 1 for nodular goiter, its step is：
First, selfheal, fritillaria, curcuma zedoary, oyster, sargentodoxa cuneata and insects are ground, 25- is made in selfheal and sargentodoxa cuneata
The particle of 35 mesh, is made fritillaria and curcuma zedoary the particle of 14-16 mesh, oyster and insects purpose particle, is passing through puddler
Selfheal, fritillaria, curcuma zedoary, oyster, sargentodoxa cuneata and insects are mixed, yellow rice wine is added, the middle medicine of pasty state is made,
2nd, 3-8 parts of white clover herb, 15-20 parts of oval kumquat root, 22-24 parts of rhizome of Kirilow Rhodiola, 3-9 parts of Fermented Soybean, 6-9 parts of cicada slough,
4-8 parts of turmeric, 10-23 parts of selfheal, 18-25 parts of dried orange peel, 8-11 parts of great burdock achene, 12-16 parts of rhizoma cyperi, Rhizoma Sparganii 10-
After 5-14 parts of 14 parts, 7-10 parts of kelp, 11-23 parts of berchemia lineata, 2-9 parts of sword bean and fructus amomi remove the gred, add according to part by weight
100：2-10 adds rice vinegar and honey, carries out immersion 40-50 minutes to Chinese medicine composition, then rice vinegar and honey are fallen
Go out, add in 1000ml water, boiled the medicament in 20-50ml.
6. a kind of Chinese medicine composition and preparation method for nodular goiter is in the application for the treatment of nodular goiter.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110393781A (en) * | 2019-07-09 | 2019-11-01 | 马学玲 | A kind of pure Chinese medicinal preparation that treating thyroid nodule and preparation method |
| CN117338893A (en) * | 2023-12-04 | 2024-01-05 | 云南中医药大学 | Pharmaceutical composition for resolving hard mass, preparation and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104524477A (en) * | 2015-01-23 | 2015-04-22 | 崔合芳 | Traditional Chinese medicine composition for treating nodular goiter |
| CN104758569A (en) * | 2015-04-08 | 2015-07-08 | 唐海英 | Drug for treating nodular goiter |
| CN105535787A (en) * | 2016-01-14 | 2016-05-04 | 青岛辰达生物科技有限公司 | Medicine preparation for treating nodular goiter and application thereof |
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2017
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104524477A (en) * | 2015-01-23 | 2015-04-22 | 崔合芳 | Traditional Chinese medicine composition for treating nodular goiter |
| CN104758569A (en) * | 2015-04-08 | 2015-07-08 | 唐海英 | Drug for treating nodular goiter |
| CN105535787A (en) * | 2016-01-14 | 2016-05-04 | 青岛辰达生物科技有限公司 | Medicine preparation for treating nodular goiter and application thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110393781A (en) * | 2019-07-09 | 2019-11-01 | 马学玲 | A kind of pure Chinese medicinal preparation that treating thyroid nodule and preparation method |
| CN117338893A (en) * | 2023-12-04 | 2024-01-05 | 云南中医药大学 | Pharmaceutical composition for resolving hard mass, preparation and application thereof |
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