CN107022117A - A kind of preparation of chitosan/calcium carboxymethylcellulose ionic oxide formation graphene composite material - Google Patents
A kind of preparation of chitosan/calcium carboxymethylcellulose ionic oxide formation graphene composite material Download PDFInfo
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- CN107022117A CN107022117A CN201710256181.8A CN201710256181A CN107022117A CN 107022117 A CN107022117 A CN 107022117A CN 201710256181 A CN201710256181 A CN 201710256181A CN 107022117 A CN107022117 A CN 107022117A
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- chitosan
- graphene oxide
- composite material
- carboxymethyl cellulose
- calcium ion
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
- C08L1/08—Cellulose derivatives
- C08L1/26—Cellulose ethers
- C08L1/28—Alkyl ethers
- C08L1/286—Alkyl ethers substituted with acid radicals, e.g. carboxymethyl cellulose [CMC]
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Carbon And Carbon Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
The present invention relates to a kind of preparation of chitosan/calcium carboxymethylcellulose ionic oxide formation graphene composite material.Comprise the following steps：Calcium carboxymethylcellulose ionic oxide formation graphene blended liquid is prepared, chitosan solution is prepared, chitosan/calcium carboxymethylcellulose ionic oxide formation graphene composite material is prepared.The beneficial effects of the invention are as follows：Chitosan/calcium carboxymethylcellulose ionic oxide formation graphene composite material is only prepared by physical force, and preparation process is without using other organic reagents, environmentally safe and can be widely applied to biomaterial.
Description
Technical field
The present invention relates to a kind of preparation of chitosan/carboxymethyl cellulose-calcium ion-graphene oxide composite material, category
In field of material preparation.
Technical background
Biomaterial is that a class is used for the reparation of tissue and organ or promotes the High-tech Material of its function, be can be used for
Substitution, the natural or artificial material for repairing biological tissue.Biomaterial can be performed, promoted or replaced because disease, damage etc. lose
Certain function, but rejected region can not be recovered.And biomaterial is needed with biological non-toxicity and degradable characteristic, therefore
As study hotspot.
Natural polysaccharide has cheap, preferable biocompatibility, biodegradability, nonhazardous and recyclability
Etc. advantage, ripe is used in the industries such as food, organizational project, environmental protection and biological medicine.Wherein chitosan and
Preparation of the carboxymethyl cellulose due to being usually used in biomaterial with special pH sensitiveness, but simple use natural polysaccharide
Preparing biomaterial has certain defect, and most importantly mechanical strength is low., will and inorganic material has preferable rigid structure
Inorganic material is mutually combined with natural polysaccharide can effectively improve the mechanical strength of material.The graphite oxide in numerous inorganic material
Alkene has larger lamellar structure, rich in substantial amounts of oxy radical and low bio-toxicity.Therefore it is graphene oxide, carboxymethyl is fine
The plain sodium of dimension, three kinds of materials of chitosan are prepared into composite.
The content of the invention
The purpose of the present invention is to be to provide a kind of chitosan/carboxymethyl cellulose-calcium ion-graphene oxide composite wood
The preparation of material.
A kind of preparation of chitosan/carboxymethyl cellulose-calcium ion-graphene oxide composite material of the present invention, bag
Include following steps：
A, prepare carboxymethyl cellulose-calcium ion-graphene oxide blended liquid：Take sodium carboxymethylcellulose and graphite oxide
Alkene is added in the beaker equipped with 150mL acetate buffer solutions, and after magnetic agitation 1h, adds 5mL calcium chloride solution, and magnetic force is stirred
Mix 30min；
B, prepare chitosan solution：Chitosan is taken to add in the beaker equipped with 50mL acetate buffer solutions, magnetic agitation 1h；
C, prepare chitosan/carboxymethyl cellulose-calcium ion-graphene oxide composite material：The step b shells prepared are gathered
Sugar juice is added in carboxymethyl cellulose-calcium ion-graphene oxide blended liquid of step a preparations, keeps magnetic agitation, most
The pH of solution is adjusted to neutrality using sodium hydroxide afterwards, natural subsidence, washing are simultaneously freeze-dried 24h at -45 DEG C.
Further, acetate buffer solution pH is 4.5~6.0 in step a.
Further, the sodium carboxymethylcellulose and the mass ratio of graphene oxide added in step a is 1~10.
Further, the concentration of calcium chloride is 1~20mg/mL in step a.
Further, acetate buffer solution pH is 4.5~6.0 in step b.
Further, the concentration of chitosan is 0~10mg/mL in step b.
Further, the concentration of sodium hydroxide is 1~10wt% in step c.
The beneficial effects of the invention are as follows：Chitosan/carboxymethyl cellulose-calcium ion-graphene oxide composite material only leads to
Cross physical force preparation, preparation process is without using other organic reagents, environmentally safe and can be widely applied to biological material
Material.
Brief description of the drawings
This experiment is further illustrated below in conjunction with the accompanying drawings.
Fig. 1 is the field emission scanning electron microscope figure of chitosan/carboxymethyl cellulose-calcium ion-graphene oxide composite material.
Embodiment
Presently in connection with specific embodiment, the present invention will be further described, following examples be intended to illustrate invention rather than
Limitation of the invention further.
Embodiment one：
Preparing chitosan/carboxymethyl cellulose-calcium ion-graphene oxide composite material includes following steps：
(1) take 300mg sodium carboxymethylcelluloses and 100mg graphene oxides to add respectively and 150mL acetate buffer solutions are housed
(pH=5.0) in beaker, and magnetic agitation 1h is kept so that carboxymethyl cellulose is inserted into the lamellar structure of graphene oxide
In, add the calcium chloride solution that 5mL concentration is 8mg/mL, magnetic agitation 30min.
(2) chitosan solution is prepared：100mg chitosans are taken to add the beaker equipped with 50mL acetate buffer solutions (pH=5.0)
In, magnetic agitation 1h causes chitosan sufficiently to protonate dissolving.
(3) chitosan dispersion for preparing step (2) pours into carboxymethyl cellulose-calcium ion-oxygen of step (1) preparation
In graphite alkene blended liquid, magnetic agitation is kept, with blended liquid electrostatic embedding effect can occur for chitosan, finally using hydroxide
Sodium (2wt%) adjusts the pH of solution to neutrality.Natural subsidence, washing are simultaneously freeze-dried 24h at -45 DEG C.As shown in Figure 1
For the field emission scanning electron microscope figure of chitosan/carboxymethyl cellulose-calcium ion-graphene oxide composite material.
Claims (7)
1. a kind of preparation of chitosan/carboxymethyl cellulose-calcium ion-graphene oxide composite material, it is characterised in that：Step
It is as follows：
A, prepare carboxymethyl cellulose-calcium ion-graphene oxide blended liquid：Sodium carboxymethylcellulose and graphene oxide is taken to add
Enter in the beaker equipped with 150mL acetate buffer solutions, and after magnetic agitation 1h, add 5mL calcium chloride solution, magnetic agitation
30min；
B, prepare chitosan solution：Chitosan is taken to add in the beaker equipped with 50mL acetate buffer solutions, magnetic agitation 1h；
C, prepare chitosan/carboxymethyl cellulose-calcium ion-graphene oxide composite material：Chitosan prepared by step b is molten
Liquid is added in carboxymethyl cellulose-calcium ion-graphene oxide blended liquid of step a preparations, is kept magnetic agitation, is finally made
The pH of solution is adjusted to neutrality with sodium hydroxide, natural subsidence, washing are simultaneously freeze-dried 24h at -45 DEG C.
2. a kind of system of chitosan/carboxymethyl cellulose-calcium ion-graphene oxide composite material according to claim 1
It is standby, it is characterized in that：The concentration of calcium chloride solution is 1~20mg/mL in the step a.
3. a kind of system of chitosan/carboxymethyl cellulose-calcium ion-graphene oxide composite material according to claim 1
It is standby, it is characterized in that：The pH scopes of acetate buffer solution are 4.5~6.0 in the step a.
4. a kind of system of chitosan/carboxymethyl cellulose-calcium ion-graphene oxide composite material according to claim 1
It is standby, it is characterized in that：The sodium carboxymethylcellulose and the mass ratio of graphene oxide added in the step a is 1~10.
5. a kind of system of chitosan/carboxymethyl cellulose-calcium ion-graphene oxide composite material according to claim 1
It is standby, it is characterized in that：The concentration of chitosan solution is 1~10mg/mL in the step b.
6. a kind of system of chitosan/carboxymethyl cellulose-calcium ion-graphene oxide composite material according to claim 1
It is standby, it is characterized in that：The pH scopes of acetate buffer solution are 4.5~6.0 in the step b.
7. a kind of system of chitosan/carboxymethyl cellulose-calcium ion-graphene oxide composite material according to claim 1
It is standby, it is characterized in that：The concentration of sodium hydroxide is 1~10wt% in the step c.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710256181.8A CN107022117A (en) | 2017-04-19 | 2017-04-19 | A kind of preparation of chitosan/calcium carboxymethylcellulose ionic oxide formation graphene composite material |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710256181.8A CN107022117A (en) | 2017-04-19 | 2017-04-19 | A kind of preparation of chitosan/calcium carboxymethylcellulose ionic oxide formation graphene composite material |
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| CN107022117A true CN107022117A (en) | 2017-08-08 |
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| CN201710256181.8A Pending CN107022117A (en) | 2017-04-19 | 2017-04-19 | A kind of preparation of chitosan/calcium carboxymethylcellulose ionic oxide formation graphene composite material |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107607601A (en) * | 2017-09-13 | 2018-01-19 | 北京理工大学 | A kind of composite electrochemical biology sensor and its production and use |
| CN116588926A (en) * | 2023-04-22 | 2023-08-15 | 青岛华腾石墨科技有限公司 | Modification process of negative electrode material for battery |
Citations (3)
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| CN105131349A (en) * | 2015-08-22 | 2015-12-09 | 苏州正业昌智能科技有限公司 | Preparation method of graphene oxide-chitosan composite material |
| CN105622960A (en) * | 2015-12-30 | 2016-06-01 | 华南理工大学 | Carboxymethyl chitosan/oxidized graphene compounded hydrogel and preparation as well as application thereof |
| CN106317433A (en) * | 2016-08-13 | 2017-01-11 | 齐齐哈尔大学 | Preparation method of flax-bit-based carboxymethylcellulose and graphene oxide composite film |
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2017
- 2017-04-19 CN CN201710256181.8A patent/CN107022117A/en active Pending
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| CN105131349A (en) * | 2015-08-22 | 2015-12-09 | 苏州正业昌智能科技有限公司 | Preparation method of graphene oxide-chitosan composite material |
| CN105622960A (en) * | 2015-12-30 | 2016-06-01 | 华南理工大学 | Carboxymethyl chitosan/oxidized graphene compounded hydrogel and preparation as well as application thereof |
| CN106317433A (en) * | 2016-08-13 | 2017-01-11 | 齐齐哈尔大学 | Preparation method of flax-bit-based carboxymethylcellulose and graphene oxide composite film |
Non-Patent Citations (3)
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| 刘浩怀等: "氧化石墨烯／羧甲基纤维素钠／海藻酸钠复合材料的制备与性能研究", 《化工新型材料》 * |
| 张锐: "羧甲基纤维素-壳聚糖复合物的制备及对乳糖酶的固定化研究", 《中国优秀硕士学位论文全文数据库基础科技辑》 * |
| 张锐等: "羧甲基纤维素-壳聚糖聚电解质复合物", 《林产化学与工业》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107607601A (en) * | 2017-09-13 | 2018-01-19 | 北京理工大学 | A kind of composite electrochemical biology sensor and its production and use |
| CN116588926A (en) * | 2023-04-22 | 2023-08-15 | 青岛华腾石墨科技有限公司 | Modification process of negative electrode material for battery |
| CN116588926B (en) * | 2023-04-22 | 2024-04-26 | 青岛华腾石墨科技有限公司 | Modification process of negative electrode material for battery |
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Application publication date: 20170808 |
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