CN107007730A - One kind treats toothache Chinese drugs agentia - Google Patents
One kind treats toothache Chinese drugs agentia Download PDFInfo
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- CN107007730A CN107007730A CN201710253598.9A CN201710253598A CN107007730A CN 107007730 A CN107007730 A CN 107007730A CN 201710253598 A CN201710253598 A CN 201710253598A CN 107007730 A CN107007730 A CN 107007730A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8964—Anemarrhena
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/65—Amphibians, e.g. toads, frogs, salamanders or newts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/634—Forsythia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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Abstract
Toothache Chinese drugs agentia is treated the present invention relates to one kind, the traditional Chinese medicine reagent is made up of following raw material：10 15 parts of gypsum, touch fragrant 9 15 parts, 9 13 parts of Euphorbia thymifolia, 11 16 parts of grandmother's fourth, 8 15 parts of frog clothing, 7 10 parts of the capsule of weeping forsythia, 58 parts of the wind-weed, 10 20 parts of white wine, 20 25 parts of 75% ethanol, distillation appropriate amount of water；Treatment toothache Chinese drugs agentia drug effect great efforts provided by the present invention, therapeutic effect is fast, and therapeutic efficiency is high, and substantially, gained anodyne efficacy stability is worthy to be popularized for mating reaction between each raw material.
Description
Technical field
The present invention relates to the field of Chinese medicines, and in particular to one kind treats toothache Chinese drugs agentia.
Background technology
Toothache refers to tooth pain caused by a variety of causes, is one of common disease in mouth disease.Most of teeth
Pain is that as caused by gingivitis and periodontitis cause infections of dental pulp, common is gum redness and caloric stimulation pain etc..Toothache
Though being indisposition, but hurt like hell, general therapeutic toothache method is more based on Western medicine anti-inflammatory analgetic, and Long-term clinical is seen
Examine actual effect unsatisfactory.
For obtaining a kind of combination with treatment toothache effect in patent application CN104273528B disclosed in China
Thing and preparation method thereof, using chrysanthemum, semen allii tuberosi, phoenix-tail fern, pepper is well mixed, crush, and adds 300~800 parts of water, decoct to
Moisture is reduced to the 1/8-1/9 of addition, and the made composition of the invention is nutritious, delicious in taste, with prevention and treatment tooth
Effect of pain.For a kind of Chinese traditional medicine composition medicine for being used to treat toothache in patent application CN104435232A disclosed in China
Thing, uses egg, white wine, the root of Dahurain angelica, cape jasmine, Ligusticum wallichii, the radix paeoniae rubrathe, pawpaw, gypsum for raw material, after raw material is crushed, egg is beaten
Enter, add white wine stirring, material therefor materials are easy, make simple, drug effect is notable.
Although the Chinese medicine composition of the made treatment toothache of currently available technology is with certain analgesic effect, drug effect power
Degree is small, and therapeutic effect is slow, and therapeutic efficiency is low, and mating reaction is not obvious between each raw material.
The content of the invention
For above-mentioned problem, the present invention proposes one kind and treats toothache Chinese drugs agentia.The present invention compensate for drug effect
Dynamics is small, and therapeutic effect is slow, and therapeutic efficiency is low, the unconspicuous defect of mating reaction between raw material.
In order to realize above-mentioned purpose, the present invention uses following technical scheme：
One kind treats toothache Chinese drugs agentia, is made up of following parts by weight raw material：10-15 parts of gypsum, touch fragrant 9-15
Part, 9-13 parts of Euphorbia thymifolia, 11-16 parts of grandmother's fourth, 8-15 parts of frog clothing, 7-10 parts of the capsule of weeping forsythia, 5-8 parts of the wind-weed, 10-20 parts of white wine,
75% 20-25 parts of ethanol, distillation appropriate amount of water.
It is preferred that, treatment toothache Chinese drugs agentia is made up of following parts by weight raw material：11-15 parts of gypsum, touch perfume (or spice)
11-15 parts, 10-13 parts of Euphorbia thymifolia, 12-16 parts of grandmother's fourth, 10-15 parts of frog clothing, 8-10 parts of the capsule of weeping forsythia, 6-8 parts of the wind-weed, white wine
12-20 parts, 21-25 parts of 75% ethanol, distillation appropriate amount of water.
It is preferred that, the preparation for the treatment of toothache Chinese drugs agentia, including following several steps：
(1) grandmother's fourth is put into container, adds the immersion of 75% ethanol, then as in ultrasonic disruption machine, at ultrasound
Decolourized after reason 45min with petroleum ether extraction, it is standby to be settled to 150ml with distilled water；
(2) solution of constant volume in (1) is put into reactor together with gypsum, stirs and allow it to react 30min；
(3) perfume, Euphorbia thymifolia, frog clothing, the capsule of weeping forsythia, the wind-weed will be touched and put grinding in sand mill into, 200-300 mesh was crushed
Sieve；
(4) leftover materials and (2), (3) products therefrom are put into fried Chinese medicine in pot together, addition is reduced to moisture
1/10, the dregs of a decoction are removed, taking liquid cooling produces treatment toothache traditional Chinese medicine reagent.
It is preferred that, soak time is 2h in step (1).
It is preferred that, the rotating speed of sand mill is 200-300r/min in step (3).
It is preferred that, it is 20-25 DEG C that temperature, which is sanded, in sand mill in step (3).
Using above-mentioned technical scheme, the beneficial effects of the invention are as follows：In raw material grandmother's fourth that the present invention is used containing flavones,
The active ingredients such as vitamin B2, inositol, resin, wherein, flavones has the effect of class superoxide dismutase, makees jointly with gypsum
With, by calcium ion in gypsum and it is some other micro- excite, can effectively be removed between active ingredient super oxygen it is cloudy from
Sub- free radical, hydroxy radical, suppress the oxidation of unrighted acid, enhance suppression tyrasamine enzymatic activity, reduce melanin
Generation and pigmentation, improve the clearing away heat to and alleviating pain effect of traditional Chinese medicine reagent.Fragrant, Euphorbia thymifolia and frog clothing three are touched with cooperation
With can improve vascular endothelial tissue, reduce the generation of internal oxygen radical, increase the removing of oxygen radical, with anti-oxidant
Stress, reduces its damage to gingival cell, so as to play protection gum, alleviate the effect of toothache.Both the capsule of weeping forsythia, wind-weed
And use can play and attack malicious analgesic, dispelling wind and eliminating swelling, clearing heat and detoxicating effect.
Embodiment
To make the purpose, technical scheme and advantage of the embodiment of the present invention clearer, below in conjunction with the embodiment of the present invention,
Technical scheme in the embodiment of the present invention is clearly and completely described.Based on embodiments of the invention, the common skill in this area
The every other embodiment that art personnel are obtained under the premise of creative work is not made, belongs to the model that the present invention is protected
Enclose.
Embodiment 1：
One kind treats toothache Chinese drugs agentia, is made up of following parts by weight raw material：10 parts of gypsum, touch fragrant 9 parts, thousand
9 parts of grass, 11 parts of grandmother's fourth, 8 parts of frog clothing, 7 parts of the capsule of weeping forsythia, 5 parts of the wind-weed, 10 parts of white wine, 20 parts of 75% ethanol, distillation appropriate amount of water.
A kind of preparation for treating toothache Chinese drugs agentia, including following several steps：
(1) grandmother's fourth is put into container, adds the immersion of 75% ethanol, then as in ultrasonic disruption machine, at ultrasound
Decolourized after reason 45min with petroleum ether extraction, it is standby to be settled to 150ml with distilled water；
(2) solution of constant volume in (1) is put into reactor together with gypsum, stirs and allow it to react 30min；
(3) perfume, Euphorbia thymifolia, frog clothing, the capsule of weeping forsythia, the wind-weed will be touched and put grinding in sand mill into, 200 mesh sieves were crushed；
(4) leftover materials and (2), (3) products therefrom are put into fried Chinese medicine in pot together, addition is reduced to moisture
1/10, the dregs of a decoction are removed, taking liquid cooling produces treatment toothache traditional Chinese medicine reagent.
Embodiment 2：
One kind treats toothache Chinese drugs agentia, is made up of following parts by weight raw material：15 parts of gypsum, touch fragrant 15 parts, thousand
13 parts of root grass, 16 parts of grandmother's fourth, 15 parts of frog clothing, 10 parts of the capsule of weeping forsythia, 8 parts of the wind-weed, 20 parts of white wine, 25 parts of 75% ethanol, distilled water
In right amount.
A kind of preparation for treating toothache Chinese drugs agentia, including following several steps：
(1) grandmother's fourth is put into container, adds the immersion of 75% ethanol, then as in ultrasonic disruption machine, at ultrasound
Decolourized after reason 45min with petroleum ether extraction, it is standby to be settled to 150ml with distilled water；
(2) solution of constant volume in (1) is put into reactor together with gypsum, stirs and allow it to react 30min；
(3) perfume, Euphorbia thymifolia, frog clothing, the capsule of weeping forsythia, the wind-weed will be touched and put grinding in sand mill into, 300 mesh sieves were crushed；
(4) leftover materials and (2), (3) products therefrom are put into fried Chinese medicine in pot together, addition is reduced to moisture
1/10, the dregs of a decoction are removed, taking liquid cooling produces treatment toothache traditional Chinese medicine reagent.
Embodiment 3：
One kind treats toothache Chinese drugs agentia, is made up of following parts by weight raw material：11 parts of gypsum, touch fragrant 11 parts, thousand
10 parts of root grass, 12 parts of grandmother's fourth, 10 parts of frog clothing, 8 parts of the capsule of weeping forsythia, 6 parts of the wind-weed, 12 parts of white wine, 21 parts of 75% ethanol, distilled water are fitted
Amount.
A kind of preparation for treating toothache Chinese drugs agentia, including following several steps：
(1) grandmother's fourth is put into container, adds the immersion of 75% ethanol, then as in ultrasonic disruption machine, at ultrasound
Decolourized after reason 45min with petroleum ether extraction, it is standby to be settled to 150ml with distilled water；
(2) solution of constant volume in (1) is put into reactor together with gypsum, stirs and allow it to react 30min；
(3) perfume, Euphorbia thymifolia, frog clothing, the capsule of weeping forsythia, the wind-weed will be touched and put grinding in sand mill into, 220 mesh sieves were crushed；
(4) leftover materials and (2), (3) products therefrom are put into fried Chinese medicine in pot together, addition is reduced to moisture
1/10, the dregs of a decoction are removed, taking liquid cooling produces treatment toothache traditional Chinese medicine reagent.
Embodiment 4：
One kind treats toothache Chinese drugs agentia, is made up of following parts by weight raw material：12 parts of gypsum, touch fragrant 12 parts, thousand
11 parts of root grass, 13 parts of grandmother's fourth, 11 parts of frog clothing, 9 parts of the capsule of weeping forsythia, 7 parts of the wind-weed, 13 parts of white wine, 22 parts of 75% ethanol, distilled water are fitted
Amount.
A kind of preparation for treating toothache Chinese drugs agentia, including following several steps：
(1) grandmother's fourth is put into container, adds the immersion of 75% ethanol, then as in ultrasonic disruption machine, at ultrasound
Decolourized after reason 45min with petroleum ether extraction, it is standby to be settled to 150ml with distilled water；
(2) solution of constant volume in (1) is put into reactor together with gypsum, stirs and allow it to react 30min；
(3) perfume, Euphorbia thymifolia, frog clothing, the capsule of weeping forsythia, the wind-weed will be touched and put grinding in sand mill into, 240 mesh sieves were crushed；
(4) leftover materials and (2), (3) products therefrom are put into fried Chinese medicine in pot together, addition is reduced to moisture
1/10, the dregs of a decoction are removed, taking liquid cooling produces treatment toothache traditional Chinese medicine reagent.
Embodiment 5：
One kind treats toothache Chinese drugs agentia, is made up of following parts by weight raw material：14 parts of gypsum, touch fragrant 14 parts, thousand
12 parts of root grass, 15 parts of grandmother's fourth, 14 parts of frog clothing, 9 parts of the capsule of weeping forsythia, 7 parts of the wind-weed, 15 parts of white wine, 24 parts of 75% ethanol, distilled water are fitted
Amount.
A kind of preparation for treating toothache Chinese drugs agentia, including following several steps：
(1) grandmother's fourth is put into container, adds the immersion of 75% ethanol, then as in ultrasonic disruption machine, at ultrasound
Decolourized after reason 45min with petroleum ether extraction, it is standby to be settled to 150ml with distilled water；
(2) solution of constant volume in (1) is put into reactor together with gypsum, stirs and allow it to react 30min；
(3) perfume, Euphorbia thymifolia, frog clothing, the capsule of weeping forsythia, the wind-weed will be touched and put grinding in sand mill into, 280 mesh sieves were crushed；
(4) leftover materials and (2), (3) products therefrom are put into fried Chinese medicine in pot together, addition is reduced to moisture
1/10, the dregs of a decoction are removed, taking liquid cooling produces treatment toothache traditional Chinese medicine reagent.
Treatment toothache Chinese drugs agentia in the embodiment of the present invention is subjected to therapeutic effect with documents CN104273528B
Test, its test result is as follows：
| Recovery from illness/ | Effectively/ | Effective/ | Invalid/ | Effective percentage/% | |
| Embodiment 1 | 172 | 65 | 245 | 18 | 96.4 |
| Embodiment 2 | 176 | 65 | 248 | 11 | 97.8 |
| Embodiment 3 | 174 | 62 | 244 | 20 | 96 |
| Embodiment 4 | 174 | 66 | 245 | 15 | 97 |
| Embodiment 5 | 173 | 64 | 242 | 21 | 95.8 |
| Reference examples | 170 | 60 | 240 | 30 | 94 |
Recovery from illness refers to what is returned to one's perfect health with toothache patient by clinical diagnosis symptom, and effective is that toothache clinical symptoms are notable
Take a turn for the better but do not fully recover, can normally chew, have a meal, effectively be that toothache symptom take a favorable turn, but can not feel like oneself once in a while, influence nozzle
Function is chewed, invalid is that toothache is appointed so without improvement after treating.As can be seen from the above table, the traditional Chinese medicine reagent of the made treatment toothache of the present invention
More more obvious than Chinese medicine composition analgesic effect in documents, therapeutic effect more preferably, is worthy to be popularized.
Above example is only to the technical scheme for illustrating type of the present invention, rather than its limitations；Although implementing with reference to foregoing
Type of the present invention is described in detail example, it will be understood by those within the art that：It still can be to foregoing each
Technical scheme described in embodiment is modified, or carries out equivalent substitution to which part technical characteristic；And these are changed
Or replace, the essence of appropriate technical solution is departed from the spirit and scope of each embodiment technical scheme of type of the present invention.
Claims (6)
1. one kind treats toothache Chinese drugs agentia, it is characterised in that be made up of following parts by weight raw material：10-15 parts of gypsum, touch
Touch fragrant 9-15 parts, 9-13 parts of Euphorbia thymifolia, 11-16 parts of grandmother's fourth, 8-15 parts of frog clothing, 7-10 parts of the capsule of weeping forsythia, 5-8 parts of the wind-weed, white wine
10-20 parts, 20-25 parts of 75% ethanol, distillation appropriate amount of water.
2. treatment toothache Chinese drugs agentia according to claim 1, it is characterised in that be made up of following parts by weight raw material：
11-15 parts of gypsum, touch fragrant 11-15 parts, 10-13 parts of Euphorbia thymifolia, 12-16 parts of grandmother's fourth, 10-15 parts of frog clothing, capsule of weeping forsythia 8-
10 parts, 6-8 parts of the wind-weed, 12-20 parts of white wine, 21-25 parts of 75% ethanol, distillation appropriate amount of water.
3. the preparation for the treatment of toothache Chinese drugs agentia according to claim 1, it is characterised in that including following several steps：
(1) grandmother's fourth is put into container, adds the immersion of 75% ethanol, it is ultrasonically treated then as in ultrasonic disruption machine
Decolourized after 45min with petroleum ether extraction, it is standby to be settled to 150ml with distilled water；
(2) solution of constant volume in (1) is put into reactor together with gypsum, stirs and allow it to react 30min；
(3) perfume, Euphorbia thymifolia, frog clothing, the capsule of weeping forsythia, the wind-weed will be touched and put grinding in sand mill into, 200-300 mesh sieves were crushed；
(4) leftover materials and (2), (3) products therefrom are put into fried Chinese medicine in pot together, the 1/ of addition is reduced to moisture
10, the dregs of a decoction are removed, taking liquid cooling produces the traditional Chinese medicine reagent for the treatment of toothache.
4. the preparation for the treatment of toothache Chinese drugs agentia according to claim 3, it is characterised in that soaked in the step (1)
Time is 2h.
5. the preparation for the treatment of toothache Chinese drugs agentia according to claim 3, it is characterised in that be sanded in the step (3)
The rotating speed of machine is 200-300r/min.
6. the preparation for the treatment of toothache Chinese drugs agentia according to claim 3, it is characterised in that be sanded in the step (3)
It is 20-25 DEG C that temperature, which is sanded, in machine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710253598.9A CN107007730A (en) | 2017-04-18 | 2017-04-18 | One kind treats toothache Chinese drugs agentia |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710253598.9A CN107007730A (en) | 2017-04-18 | 2017-04-18 | One kind treats toothache Chinese drugs agentia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107007730A true CN107007730A (en) | 2017-08-04 |
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ID=59447093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710253598.9A Pending CN107007730A (en) | 2017-04-18 | 2017-04-18 | One kind treats toothache Chinese drugs agentia |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108324832A (en) * | 2018-04-26 | 2018-07-27 | 马玉玲 | It is a kind of to treat toothache Chinese drugs agentia |
-
2017
- 2017-04-18 CN CN201710253598.9A patent/CN107007730A/en active Pending
Non-Patent Citations (1)
| Title |
|---|
| 赵进喜等: "《糖尿病临床药对新用》", 31 December 2006, 中国医药科技出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108324832A (en) * | 2018-04-26 | 2018-07-27 | 马玉玲 | It is a kind of to treat toothache Chinese drugs agentia |
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Application publication date: 20170804 |