CN107007650A - Fresh horizontal root takes application of the vegetable juice in treatment pruitus medicine is prepared - Google Patents
Fresh horizontal root takes application of the vegetable juice in treatment pruitus medicine is prepared Download PDFInfo
- Publication number
- CN107007650A CN107007650A CN201710249718.8A CN201710249718A CN107007650A CN 107007650 A CN107007650 A CN 107007650A CN 201710249718 A CN201710249718 A CN 201710249718A CN 107007650 A CN107007650 A CN 107007650A
- Authority
- CN
- China
- Prior art keywords
- fresh
- horizontal root
- vegetable juice
- medicine
- juice
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/41—Crassulaceae (Stonecrop family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
Abstract
Take application of the vegetable juice in treatment pruitus medicine is prepared the invention discloses fresh horizontal root, the present invention is through pharmacodynamic experiment, as a result show that fresh horizontal root expense vegetable juice has obvious antipruritic, antiinflammatory action, and have no toxic action, and horizontal root takes dish resource extensively, cost is relatively low, Sustainable Exploitation, application prospect extensively, is expected to develop into the medicine of new treatment pruitus.
Description
Technical field
The invention belongs to pharmaceutical technology field, more particularly to a kind of fresh horizontal root takes vegetable juice and is preparing treatment pruitus medicine
In application.
Background technology
Cutaneous pruritus be it is a kind of only pruitus and without primary cutaneous damage dermatology common disease, frequently-occurring disease it
One.The disease is in rising trend in recent years, the application of mainly a large amount of chemical articles, and environmental pollution, or intrinsic disease
Epidermis reacts, and is mainly shown as locality or systemic, in paroxysmal, can last for hours every time, especially using night as very, seriously
Influence the work and life of patient.If scratched during pruitus with hand, usually can bleeding, easily cause infection.Some patientss are taken
Oral drugs, being used for a long time can cause damage to other internal organs again.The medicine for the treatment of pruitus is most based on Western medicine at present,
Such as histamine receptor antagonists, glucocorticoid, immunomodulator, though these Western medicine can alleviate the symptom of itch, are easier to
Tolerance, high recurrence rate, and it is often accompanied by certain side effect.Therefore, a kind of good effect, uneasy to recur, few side effects medicines are developed
With urgent clinical demand.
Horizontal root takes dish (Sedum kamtschaticum Fish) for Crassulaceae Sedum perennial herb, also known as Rupture history
Red-spotted stonecrop, slabstone dish, dishes made from scrambled eggs are sub, take dish, invaluable, northern red-spotted stonecrop, are distributed in the ground such as production Shanxi, Hebei, the Inner Mongol, Jilin.Have
Promoting blood circulation, hemostasis, calming heart, dampness removing, detumescence, effect of removing toxic substances, for treat traumatic injury, hemoptysis, spit blood, have blood in stool, palpitaition, carbuncle
Swollen, with edible, medical value well, application prospect is extensive.But the basic research for taking dish about horizontal root is still extremely limited, makes
The follow-up promotion and application of the medicinal material are restricted, and have no about horizontal root expense dish the public affairs as medicine for treating pruitus
Open report.
The content of the invention
In order to overcome the shortcoming of above-mentioned prior art, take vegetable juice in preparation it is an object of the invention to provide the fresh horizontal root of one kind
The application in pruitus medicine is treated, i.e., fresh horizontal root takes the medicine that vegetable juice can be used for preparing treatment pruitus.
To achieve these goals, the technical solution adopted by the present invention is：
Fresh horizontal root takes application of the vegetable juice in treatment pruitus medicine is prepared, raw materials used：Horizontal root takes dish for Crassulaceae
The horizontal root of plant takes dish (Sedum kamtschaticum Fish) fresh herb.
The preparation method of fresh horizontal root expense vegetable juice is：Fresh horizontal root expense dish herb is taken, cleans, drains, segment is squeezed the juice, filter
Degerming to obtain the Fresh sap containing fresh 2~12g/mL of crude drug except precipitation, sealing, 2-8 DEG C of refrigeration is standby.
The exterior-applied formulation in pharmacy is made in the various auxiliary materials that the fresh horizontal root expense vegetable juice is allowed by adding pharmacy.
Described exterior-applied formulation is cream, ointment, film, tincture, liniment, spray or gel etc..
To further illustrate application of the fresh horizontal root expense vegetable juice of the present invention in treatment pruitus medicine is prepared, to the present invention
Fresh horizontal root expense vegetable juice has carried out antipruritic, anti-inflammatory pharmacological action experiment.Test result indicates that, fresh horizontal root, which takes vegetable juice, has obvious suppression
Dextran processed causes itch effect and suppresses ear swelling effect caused by dimethylbenzene.
Compared with prior art, the beneficial effects of the invention are as follows：Fresh horizontal root takes vegetable juice, and there is obvious antipruritic, anti-inflammatory to make
With no obvious toxic-side effects, horizontal root takes dish resource extensively, is easy to get, cost is relatively low, and Sustainable Exploitation, application prospect extensively, shows
It can be further used as new treatment pruitus medicine and be researched and developed.It is expected to alleviate conventional treatment skin clinical at present
There is different degrees of adverse reaction in itch medicine, be also easy to produce drug resistance and.
Embodiment
Embodiment of the present invention is described in detail below in conjunction with embodiment, but those skilled in the art will
Understand, the following example is merely to illustrate the present invention, and should not be taken as limiting the scope of the invention.It is unreceipted specific in embodiment
Condition person, the condition advised according to normal condition or manufacturer is carried out.Agents useful for same or the unreceipted production firm person of instrument, be
Can be by the conventional products of acquisition purchased in market.
Embodiment 1：Fresh horizontal root takes the preparation of vegetable juice sample 1
Fresh horizontal root expense dish herb 1kg is taken, cleans, drains, segment is squeezed the juice, filtration sterilization obtains containing fresh life except precipitation
Medicine 2g/mL Fresh sap, sealing is refrigerated at 2-8 DEG C, standby.
Embodiment 2：Fresh horizontal root takes the preparation of vegetable juice sample 2
Fresh horizontal root expense dish herb 1kg is taken, cleans, drains, segment is squeezed the juice, filtration sterilization obtains containing fresh life except precipitation
Medicine 8g/mL Fresh sap, sealing is refrigerated at 2-8 DEG C, standby.
Embodiment 3：Fresh horizontal root takes the preparation of vegetable juice sample 3
Fresh horizontal root expense dish herb 1kg is taken, cleans, drains, segment is squeezed the juice, filtration sterilization obtains containing fresh life except precipitation
Medicine 12g/mL Fresh sap, sealing is refrigerated at 2-8 DEG C, standby.The present invention takes fresh horizontal root expense dish complete in specific implementation
Grass, cleans, drains, segment is squeezed the juice, and juice is made except precipitation in filtration sterilization, be placed in it is fresh-keeping in container, or it is existing squeeze it is existing use, it is best
Auxiliary material will to be added in juice, be made cream with long preservation period, ointment, film, tincture, liniment, emulsion, spray or
The exterior-applied formulations such as gel, in favor of industrialized production and convenient use.
Pharmacodynamics test of the present invention：
The present invention is antipruritic, the experimental study of antiinflammatory action experiment：
Tested with medicine prepared by embodiment 1.
Test the influence of a pair of dextran induction mouse skin itch
Experimental animal：Kunming mouse 50,18~22g of body weight, male and female half and half, by The Fourth Military Medical University, animal center is carried
For.
Test method：Mouse 50, is randomly divided into 5 groups, every group 10, if model group (physiological saline), positive controls
(skin must pacify), high dose group (former fresh juice), middle dose group (2 times of fresh juice of dilution of physiological saline) and low dose group (4 times of physiological saline
Dilute fresh juice).Dorsal portion shaving 2cm × 2cm after each group mouse is right, presses 0.1mL/cm by medicine group or physiological saline group respectively2
Uniform to be applied to shaving area, it is 2mm (equivalent to 0.3g/cm to smear skin to pacify ointment thickness2), last dose is after 30 minutes, to each
The group dextran 0.1mL/10g of mouse tail vein injection 0.16%, is scratched head with mouse fore paw, after grab trunk of scratching, mouth is stung
Each position of whole body is used as itch index.Mouse itching number of times and itching duration in observed and recorded 30min.It the results are shown in Table 1.
The horizontal root of table 1 take dish to dextran induce mouse skin itch influence (N=10)
Note：Compared * p with model group<0.05, * * p<0.01.
Result of the test：Compared with model group, the fresh horizontal root expense high, medium and low dosage group of vegetable juice of the present invention can substantially reduce the right side
The sugared acid anhydride of rotation causes mouse itch number of times, is compared with model group with statistical significance (p<0.05, p<0.01).Point out fresh horizontal stroke of the invention
Root expense vegetable juice external application has obvious itching-relieving action.
Test the influence of two paraxylene induced mice auricle edemas
Experimental animal：Kunming mouse 50,18~22g of body weight, male and female half and half, by The Fourth Military Medical University, animal center is carried
For.
Test method：Mouse 50, is randomly divided into 5 groups, every group 10, body weight is uniform.Be divided into model group (physiological saline),
If model group (physiological saline), positive controls (Triamcinolone acetonide), high dose group (former fresh juice), middle dose group (2 times of physiological saline
Dilute fresh juice) and low dose group (4 times of fresh juice of dilution of physiological saline).Test auricle coating 1 time, model on the right side of same day each group animal
Group such as is coated with the normal saline solution of capacity, and it is 2mm (equivalent to 0.003g/ that positive controls, which smear Triamcinolone acetonide ointment thickness,
cm2).Each group washes away decoction with distilled water after 1h, and cotton balls is cleaned；The μ L/ of dimethylbenzene 20 are applied to mouse right ear only, and left ear is compared.
The neck that breaks after 15min puts to death animal, cuts ears along auricle baseline, auricle is swept away in left and right ear same position with 6mm corneal trephines,
Weighed on electronic analytical balance and (be accurate to 0.1mg), auris dextra weight subtracts the difference as swelling of left ear weight, calculate swollen
Expansibility, and swelling inhibiting rate is obtained, it as a result see the table below 2.
The horizontal root of table 2 takes the influence that dish paraxylene causes mice auricle swelling
Note：Compared * p with physiological saline group<0.05, * * p<0.01
Swelling (mg)=auris dextra auricle weight (mg)-left ear auricle weight (mg)
Swelling inhibiting rate=(the average swelling of the average swelling-administration group of control group) average swelling of/control group ×
100%
Result of the test：Compared with model group, the fresh horizontal root expense high, medium and low dosage group of vegetable juice of the present invention can significantly inhibit two
Swelling caused by toluene, the significant difference (p compared with model group<0.01) the fresh horizontal root expense vegetable juice external application of the present invention, is pointed out to have bright
Aobvious antiinflammatory action.
The preparation of medicine
Embodiment 4：Horizontal root takes the preparation of dish spray
Fresh horizontal root expense vegetable juice 400mL, Tween-80 20g, sodium benzoate 3g, glycerine 20mL are weighed, appropriate second is added
Alcohol, slowly adds distilled water 500mL stirrings, is allowed to dissolve, be sterile filtered by several times, and distilled water is added from filter to 1000mL points
Dress, is produced.
Embodiment 5：Horizontal root takes the preparation of dish gel
Weigh 6g Acritamer 940s to be dissolved in 250mL distilled water, gentle agitation is stood overnight, obtain I phase；Weigh propane diols
I phase is added under the conditions of 120g, glycerine 80g, magnetic stirrer, II phase is obtained；Fresh horizontal root expense vegetable juice 400mL is weighed, is dissolved in
In 250mL ethanol distillation water, II phase is added, stirs, obtains III phase；Weigh 15g azones and add III phase, stir, with suitable
Measuring triethanolamine adjusts pH value to be 6~7, plus distilled water is fully stirred evenly to 1000g, is deaerated, is sterilized, embedding is produced.
Embodiment 6：Horizontal root takes the preparation of dish tincture
Take in fresh horizontal root expense vegetable juice 400mL, the ethanol for adding 500mL mass concentrations 70%, stirring and dissolving, and add bay
Azone is mixed.Separately take glycerine and appropriate distilled water to stir evenly, be slowly added into above-mentioned alcoholic solution, it is stirring while adding, finally add and steam
Distilled water is stirred evenly to 1000mL, packing, is produced.
Acute toxicity test
Experimental method：Healthy rat 80 is selected, male and female dual-purpose takes off rat back in 24h before experiment with 8% vulcanized sodium
Diamond wool about 40cm2, wherein 40 rats keep skin not to be damaged completely, it is randomly divided into 4 groups, every group 8, i.e. bare substrate pair
According to group, low dose group (70g crude drugs/kg), middle dose group (140g crude drugs/kg), high dose group (280g crude drugs/kg).During experiment
Fresh horizontal root expense vegetable juice spray is uniformly applied to hair removal section.With fine sandpaper in above-mentioned rat depilation portion during another 40 rat experiments
Scratch is caused in position, skin is occurred behind intensive blutpunkte, is administered immediately in scratch site, is grouped acute with intact skin with dosage
Toxicity test.In 24h, animal coating number of times is 2 times, and breathable films, gauze are coated with after administration, and the wrapping of blend compounds cloth is fixed, point
Cage is raised.After 24h, the tested material of residual is removed with warm water, Continuous Observation 14 days, the body weight of recording laboratory animal observes animal
Diet, skin, hair, change and breathing, the central nervous system of eyes and mucous membrane, four limbs activity wait whether poisoning manifestations record
Death is whether there is, if there is death to perform an autopsy on sb. immediately, if visual inspection has obvious abnormal, Histopathology inspection is further carried out
Look into.
Experimental result：Start observation removing tested material l h, until the 14th day, intact skin group and damaged skin group are big
Mouse activity freely, is looked for food normal, skin and hair gloss is normal at coating, and eye is unchanged with mucous membrane, breathes without exception, in having no
Pivot nervous system is abnormal, has no rat body toxic reaction, and no rats death shows the fresh horizontal root expense vegetable juice outer used time without acute poison
Property reaction.
Described above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For member, under the premise without departing from the principles of the invention, some improvements and modifications can also be made, these improvements and modifications also should
It is considered as protection scope of the present invention.
Claims (8)
1. fresh horizontal root takes application of the vegetable juice in treatment pruitus medicine is prepared.
2. fresh horizontal root takes application of the vegetable juice in treatment pruitus medicine is prepared according to claim 1, it is characterised in that
The preparation method of the fresh horizontal root expense vegetable juice is：Fresh horizontal root expense dish herb is taken, cleans, drains, segment is squeezed the juice, filtration sterilization
Except precipitation, the Fresh sap containing fresh 2~12g/mL of crude drug is obtained, sealing, 2-8 DEG C of refrigeration is standby.
3. fresh horizontal root takes application of the vegetable juice in treatment pruitus medicine is prepared according to claim 2, it is characterised in that
Described to squeeze the juice from spiral mode of squeezing the juice, it is more dry better to squeeze the juice, no longer excessive for degree with juice.
4. fresh horizontal root takes application of the vegetable juice in treatment pruitus medicine is prepared according to claim 1, it is characterised in that
The exterior-applied formulation in pharmacy is made in the various auxiliary materials that the fresh horizontal root expense vegetable juice is allowed by adding pharmacy.
5. fresh horizontal root takes application of the vegetable juice in treatment pruitus medicine is prepared according to claim 1, it is characterised in that
Described exterior-applied formulation is cream, ointment, film, tincture, liniment, spray or gel.
6. fresh horizontal root takes application of the vegetable juice in treatment pruitus medicine is prepared according to claim 5, it is characterised in that
The spray is prepared as follows：
Fresh horizontal root expense vegetable juice 400mL, Tween-80 20g, sodium benzoate 3g, glycerine 20mL are weighed, ethanol in proper amount is added, delays
It is slow to add distilled water 500mL stirrings by several times, it is allowed to dissolve, is sterile filtered, distilled water is added from filter and is dispensed to 1000mL, i.e.,
.
7. fresh horizontal root takes application of the vegetable juice in treatment pruitus medicine is prepared according to claim 5, it is characterised in that
The gel is prepared as follows：
Weigh 6g Acritamer 940s to be dissolved in 250mL distilled water, gentle agitation is stood overnight, obtain I phase；Weigh propane diols 120g,
I phase is added under the conditions of glycerine 80g, magnetic stirrer, II phase is obtained；Fresh horizontal root expense vegetable juice 400mL is weighed, 250mL second is dissolved in
In alcohol distilled water, II phase is added, stirs, obtains III phase；Weigh 15g azones and add III phase, stir, with appropriate three ethanol
Amine adjusts pH value to be 6~7, plus distilled water is fully stirred evenly to 1000g, is deaerated, is sterilized, embedding is produced.
8. fresh horizontal root takes application of the vegetable juice in treatment pruitus medicine is prepared according to claim 5, it is characterised in that
The tincture is prepared as follows：
Take in fresh horizontal root expense vegetable juice 400mL, the ethanol for adding 500mL mass concentrations 70% and obtain alcoholic solution, stirring and dissolving, and add
Enter Laurocapram mixing, separately take glycerine and appropriate distilled water to stir evenly, be slowly added into above-mentioned alcoholic solution, it is stirring while adding, most
Afterwards plus distilled water is to 1000mL, stir evenly, dispense, produce.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710249718.8A CN107007650A (en) | 2017-04-17 | 2017-04-17 | Fresh horizontal root takes application of the vegetable juice in treatment pruitus medicine is prepared |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710249718.8A CN107007650A (en) | 2017-04-17 | 2017-04-17 | Fresh horizontal root takes application of the vegetable juice in treatment pruitus medicine is prepared |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107007650A true CN107007650A (en) | 2017-08-04 |
Family
ID=59448404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710249718.8A Pending CN107007650A (en) | 2017-04-17 | 2017-04-17 | Fresh horizontal root takes application of the vegetable juice in treatment pruitus medicine is prepared |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107007650A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114886845A (en) * | 2022-05-25 | 2022-08-12 | 洛阳师范学院 | Preparation method and application of fresh aizoon stonecrop branch and leaf itching relieving liquid medicine with homology of medicine and food |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101704539B1 (en) * | 2015-05-20 | 2017-02-09 | 한국과학기술연구원 | Composition for anti-allergy and skin hydration comprising sedum kamtschaticum extracts |
-
2017
- 2017-04-17 CN CN201710249718.8A patent/CN107007650A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101704539B1 (en) * | 2015-05-20 | 2017-02-09 | 한국과학기술연구원 | Composition for anti-allergy and skin hydration comprising sedum kamtschaticum extracts |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114886845A (en) * | 2022-05-25 | 2022-08-12 | 洛阳师范学院 | Preparation method and application of fresh aizoon stonecrop branch and leaf itching relieving liquid medicine with homology of medicine and food |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| WO2021103581A1 (en) | Skin topical composition having efficacy of promoting wound healing and/or scar repair | |
| CN104784270B (en) | A kind of swelling and pain relieving external preparation and preparation method thereof | |
| JP2021505650A (en) | Ophthalmic drug preparations and their use | |
| KR100699790B1 (en) | Pharmaceutical composition for the prevention and treatment of liver disease comprising a Lonicera caerulea L. var. edulis extract | |
| CN101380375B (en) | External traditional Chinese medicine preparation for treating bone and soft tissue injury and preparation method thereof | |
| CN112370496A (en) | Application of effective components of Lycii folium in preparing medicine for preventing or treating hepatic fibrosis | |
| CN107007650A (en) | Fresh horizontal root takes application of the vegetable juice in treatment pruitus medicine is prepared | |
| CN105943666A (en) | Composition for nursing infant and young child sensitive skin and preparation method thereof | |
| CN112057491A (en) | Application of copperleaf herb water extract in preparation of weight-losing and lipid-lowering medicines or weight-losing and lipid-lowering health-care products | |
| CN112057568B (en) | Traditional Chinese medicine composition for treating infantile anal fissure and application thereof | |
| CN106924326A (en) | A kind of horizontal root takes dish extract and its production and use | |
| CN108078868A (en) | A kind of antiallergic composition for skin care item | |
| CN1660345A (en) | Prepared Chinese medicine for treating burn and scald | |
| CN113876786A (en) | Medicine for preventing and treating hepatic fibrosis | |
| Hapsari et al. | Burn healing with binahong (Anredera cordifolia (Tenore) Steenis) leaves extract as a topical and systemic treatments | |
| CN112807318B (en) | Application of 1,2,3,4, 6-O-pentagalloyl glucose in preparation of drugs for preventing and/or treating pulmonary fibrosis | |
| CN100420458C (en) | Externally applied Chinese traditional medicine formulation and its preparing method | |
| CN109453146A (en) | Composition of resisting pathogenic microbes and its preparation method and application | |
| CN109771394B (en) | Agastache rugosus anti-inflammation film coating agent and preparation method thereof | |
| Johnson et al. | Evaluation of Ethanolic Extract of Tridax procumbens Linn on Wound Healing in Rats | |
| CN103735494B (en) | External antipruritic ointment for treating mosquito bite and preparation method of external antipruritic ointment | |
| CN107669931A (en) | A kind of medicine for reducing furazolidone clinical treatment chronic enteritis side effect | |
| CN112237600B (en) | Application of compound zanthoxylum bungeanum gel in preparation of product for preventing and/or treating chilblain | |
| CN102068572B (en) | Pedate pinallia jackinthepulpit rhizome externally applied preparation for treating bruises | |
| CN109106916B (en) | A Chinese medicinal composition for treating rheumatic arthritis, and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20170804 |
|
| WD01 | Invention patent application deemed withdrawn after publication |