CN106998680A

CN106998680A - Method for handling seed rice

Info

Publication number: CN106998680A
Application number: CN201580066411.3A
Authority: CN
Inventors: P·赫洛德; K·M·奈特
Original assignee: Bayer CropScience AG
Current assignee: Bayer CropScience AG
Priority date: 2014-10-07
Filing date: 2015-10-06
Publication date: 2017-08-01
Also published as: KR20170066565A; PH12017500648A1; WO2016055439A8; WO2016055439A1

Abstract

The present invention provides a kind of method for being used to prepare the seed rice being coated, wherein seed pelleting to be applied to the surface of dry seed rice at least in part, it is characterised in that the seed pelleting includes at least one EVAc and at least one agricultural chemicals.The present invention also provides a kind of seed rice of coating, and a kind of method for being used to protect the newborn rice shoot resistance fungal disease of rice plant and/or harmful organism before planting.

Description

Method for handling seed rice

The present invention relates to the method for preparing coated rice seed, wherein seed pelleting to be applied to dry seed rice at least in part Surface, be related to the seed rice of coating and for protecting the newborn rice shoot of rice plant to resist fungal disease and/or evil before planting The method of worm.

It is known for transplanting rice and/or for preventing and treating the prophylactic of animal pest and handling, wherein by agriculturalization Product are sprayed to or particle are applied into rice field or nursery box (nursery box).However, it is this transplant to behind rice field in rice The disease and/or preventing and treating animal pest of rice is prevented to there are problems that on field using agricultural chemicals, so as to need substantial amounts of agriculture It is not long with chemicals, or the effect duration of agricultural chemicals.Even if working as granular agricultural chemical spray or administration To that can reduce the amount of agricultural chemicals during nursery box compared with rice field, the consumption of agricultural chemicals is still in some cases It is very big, and the durability of effect is not enough.

Seed rice can be soaked and be cultivated prior to seeding.In order to protect seed rice, agricultural chemicals particularly fungicide can be added Into soaking water, or (Japanese Unexamined Patent Publication No is added directly in seed before transplanting after steeping or after germination 9224424, Japanese Unexamined Patent Publication No 11028006, Japanese Unexamined Patent Publication No 11049612).However, the strategy is simultaneously It is not always satisfactory because the concentration retained on seed of used agricultural chemicals may be not enough, and respectively after cultivation or It is washed off after transplanting, so that the protection to disease or insect is not enough.

For example, the B1 of EP 1 078 563 describe the seed coating composition for low application, wherein using comprising poly- The coated composition of compound and at least one active component carrys out capsuled seed.These compositions can be used for the seed rice directly sowed, But if being soaked and being cultivated first before seed rice sowing, be washed off due to being coated, be then inapplicable for seed rice.

It is therefore an object of the present invention to improve these shortcomings and with conventional seedbed system case processing used in agrochemicals The amount of product compares the consumption for significantly decreasing agricultural chemicals, and provides for prevention disease and/or preventing and treating in transplanting rice The method of animal pest, this method is simple and relatively cheap, and with long residual effect in rice field.

By specializing in for being carried out to solve the above problems, inventor has found, by using at least one ethene- Vinyl acetate copolymer handles seed rice with least one agricultural chemicals, available to be soaked in water and in agrochemicals The coated rice seed that product are cultivated in the case of not washing off substantially.It was unexpectedly found that, vinyl-vinyl acetate copolymer tool There are enough water permeabilities, so that soak and cultivate unobstructed, therefore compared with undressed seed rice, generally observation Less than or only observe germination percentage decline a little.Meanwhile, the vinyl-vinyl acetate copolymer is not dissolved in soaking water, and It can be used as the matrix or substrate of such as agricultural chemicals.

Therefore, first embodiment of the invention is the method for preparing the seed rice being coated, wherein by seed pelleting extremely Partially be applied to the surface of dry seed rice, wherein the method is characterized in that, the seed pelleting include at least one ethene- Vinyl acetate copolymer and at least one agricultural chemicals.

In the present invention, any polymer of the term " copolymer " to contain two or more different monomers.Especially Ground, the polymer comprising 3 or 4 kind of different monomers is also considered as " copolymer " of the present invention.

Term " dry seed rice " means the rice of following form, and it is suitable to storage to be used as seed in the future.The seed rice can With the typical residual water content for seed rice, such as 20 weight % or less, particularly 15 weight % or less, preferably 14 weight % or less.The water content can by such as Pfeuffer HE50 of the moisture analyser conventionally used for cereal, or according to Karl-Fischer methods are determined by titrating.

Seed can it is coated once or for several times, and each coatings can have identical or different composition.For example, inner coating layer Can be comprising vinyl-vinyl acetate copolymer and at least one fungicide, and next outer layer can include at least one desinsection Agent and optionally adhesive (polymer adhesives of such as any suitable species) or heretofore described ethane-acetic acid ethyenyl Ester copolymer.

According to a preferred embodiment of the invention, the copolymer is by preparing at least following monomer reaction：

A) vinyl acetate,

B) (methyl) acrylic monomer of formula (I) is led to

Wherein R is the saturation with least three carbon atom or unsaturated organic group, and R' is hydrogen or methyl, and

C) ethene.

These monomers preferably exist with following amount：The weight % of vinyl acetate 35 to 50 weight %, particularly 38 weights Measure % to 48 weight %, preferably 40 weight % to 45 weight %；The weight % to 55 of (methyl) acrylic monomer 25 of logical formula (I) Weight %, particularly 30 weight % to 50 weight %, preferably 35 weight % to 45 weight %, particularly preferred 35 weight % to 40 weights Measure %；The weight % of ethene 5 to 25 weight %, particularly 8 weight % to 20 weight %, preferably 10 weight % to 18 weight %；With And the weight % of acrylic acid 0 to 5 weight %, particularly 0.1 weight % to 4.5 weight %, preferably 0.5 weight % to 4.0 weight %.

In the embodiment of a replacement, these monomers preferably exist with following amount：The weight of vinyl acetate 35 Measure % to 50 weight %, particularly 38 weight % to 48 weight %, preferably 40 weight % to 45 weight %；(the first of logical formula (I) Base) 25 weight % to 55 weight % of acrylic monomer, particularly 30 weight % to 50 weight %, preferably 35 weight % to 45 weights Measure %, particularly preferred 35 weight % to 40 weight %；The weight % of ethene 5 to 25 weight %, particularly 10 weight % to 25 weights Measure %, preferably 15 weight % to 23 weight %.

In a further preferred embodiment, in addition to above component, acrylic acid exist amount for 0 weight % to 5 weight %, Particularly 0.1 weight % to 4.5 weight %, preferably 0.5 weight % are to 4.0 weight %.

This copolymer is favourable, because it can effectively prevent agricultural chemicals in immersion and cultivating process by from kind Washed off on son, while still having enough water permeabilities.If in addition, this copolymer is used as into aqueous based dispersions, can add The most of agricultural chemicals of adduction mixing and the dispersion stablized, this causes further processing, i.e. the coating of seed is easy In operation.Finally, the copolymer of the monomer with above-mentioned amount provides viscosity at ambient temperature, and this, which is conducive to being coated, fixes On seed.

(methyl) acrylic monomer is defined as：Acrylic monomer (i.e. R'=H), the metering system of Formulas I of Formulas I Acrylic monomer (i.e. R'=CH₃), or both mixture.

In a preferred embodiment, the copolymer is free of acrylic acid.

In an especially preferred embodiment, the copolymer is by vinyl acetate, (methyl) propylene of logical formula (I) Acrylic monomer and ethene composition.

It is highly preferred that vinyl acetate, 35 weight %s to 45 weights of the copolymer by 40 weight % to 45 weight % % ethylhexyl acrylate and 15 weight % to 23 weight % ethene composition are measured, the wherein polymer is free of and is chemically bonded in Acrylic acid in the polymer.

As do not otherwise indicated, in this application, generally and especially, the percentage of monomer adds up to 100%.

Copolymer for the inventive method can be prepared by any method known to those skilled in the art.Especially Ground, only as an example, the copolymer can be prepared by free-radical emulsion polymerization.The emulsion can use the standard emulsion under pressure Polymerisation routes are manufactured, and it is widely used in the copolymer that gaseous monomer (such as ethene) is included in manufacture.The emulsion can be using interval Prepared by formula, semibatch or continuous feed formula, all three technologies are used in industry.

(methyl) acrylic monomer of logical formula (I) can be that is, a kind of comprising one or more (methyl) alkyl acrylates Or a variety of (methyl) alkyl acrylate monomers.Useful (methyl) alkyl acrylate includes tertiary alkyl alcohol or non-tert-alkyl alcochol Unsaturated (methyl) acrylate of straight or branched simple function, its alkyl has 4 to 15, particularly 5 to 10 carbon atoms, Substituent R i.e. in Formulas I has 4 to 15, particularly 5 to 10 carbon atoms, and R is preferably chosen from normal-butyl, n-pentyl, just Hexyl, cyclohexyl, different heptyl, n-nonyl, positive decyl, isohesyl, isobornyl, 2- ethyloctanyls, iso-octyl, 2- ethyl hexyls Base, tetrahydrofurfuryl, ethoxyethoxyethyl, Phenoxyethyl, ring trimethyl propane dimethoxym ethane, 3,3,5- 3-methyl cyclohexanols Base, tert-butylcyclohexyl and/or the tert-butyl group.In other words, the example of these alkyl acrylates includes acrylic acid and methyl-prop The N-butyl of olefin(e) acid, n-pentyl ester, just own ester, cyclohexyl, isocyanate, positive nonyl ester, positive last of the ten Heavenly stems ester, dissident's ester, isobornyl thiocyanoacetate, 2- ethyls Monooctyl ester, different monooctyl ester, 2- ethylhexyls, tetrahydrochysene chaff ester, ethoxy ethoxyethyl acrylate, phenoxy ethyl, the contracting of ring trimethyl propane first Aldehydo-ester, 3,3,5- 3-methyl cyclohexanols ester, t-butyl cyclohexyl methacrylate, the tert-butyl ester.It is preferred that alkyl acrylate include acrylic acid it is different pungent Ester, 2-EHA, n-butyl acrylate, tetrahydrofurfuryl acrylate, isobornyl acrylate, ethioxy second Epoxide ethyl ester, acrylate, acrylic acid 3,3,5- 3-methyl cyclohexanols ester and cyclohexyl acrylate.

In a further preferred embodiment, the copolymer is ethylene-acrylic acid 2- ethylhexyls-vinyl acetate Copolymer.

The glass transition temperature Tg of the copolymer used in the present invention can be -100 DEG C to 20 DEG C, and the vitrifying turns Temperature Tg is according to DIN 53 765, by dynamic DSC, using nitrogen as inert gas, using tangential method Measured in the case of in the 20K/min rates of heat addition and Tg is defined as into neutral temperature, and in particular -60 DEG C to 20 DEG C of Tg, It is preferred that -10 DEG C or lower, more preferably -20 DEG C or lower.Particularly preferred Tg is -60 DEG C to 0 DEG C, -60 DEG C to -20 DEG C or -60 DEG C To -40 DEG C.So it is favourable, because the copolymer can keep elastic and viscous under the conditions of the normal storage temperature of seed rice Property, thus it is good fixed to realize coating, and can avoid being coated delamination.

The copolymer can in any form well known by persons skilled in the art, be preferably applied to kind in the form of dispersion Son.It is preferred that aqueous based dispersions, because negative effect of the solvent for germination percentage need not be worried.Seed rice is done after coating is applied It is dry.This can be completed at room temperature or only slightly elevated temperature, at such as 30 or 35 DEG C.Also it can be done using such as blowing warm air or spraying Dry technology.

For ease of operation, the Brookfield viscosity of the copolymer dispersion can for 500 to 30,000mPas, especially It is 1,000 to 30,000mPas, preferably 1,500 to 20,000mPas, more preferably 2,000 to 10,000mPas should Brookfield viscosity is according to DIN EN ISO 2555, and using RVT, No. 4 rotors are measured at 20rpm and 25 DEG C.This causes Coating process is relatively easy to, while ensuring to reach desired coating thickness.Otherwise, coating may be repeated once or for several times and together When drying steps are carried out after each coating steps, until reaching desired coating thickness.Extra coatings can be free of Agricultural chemicals, thus it is used as protective layer.

In one embodiment, the weight average molecular weight Mw of copolymer of the invention can be in 10,000 to 300,000g/ In the range of mol, preferably 100,000 to 300,000g/mol, more preferably 125,000 to 300,000g/mol；Even more preferably 200,000 to 280,000g/mol, such as 240,000 ± 10,000g/mol, and the monomer preferably deposited with following amount ：The weight % of vinyl acetate 35 to 50 weight %, particularly 38 weight % to 48 weight %, preferably 40 weight % to 45 weights Measure %；The weight % of (methyl) acrylic monomer 25 to 55 weight % of logical formula (I), particularly 30 weight % to 50 weight %, It is preferred that 35 weight % to 45 weight %, particularly preferred 35 weight % are to 40 weight %；The weight % of ethene 5 to 25 weight %, especially It is 10 weight % to 25 weight %, preferably 15 weight % to 23 weight %；Wherein described copolymer is free of acrylic acid.

In one embodiment, the weight average molecular weight Mw of copolymer of the invention can be in 10,000 to 125,000g/ In the range of mol, wherein in the first embodiment, the weight average molecular weight Mw of present copolymer can 10,000 to 75, In the range of 000g/mol, preferably 10,000 to 25,000g/mol, more preferably 10,000 to 18,000g/mol；And it is real second Apply in scheme is 75,000 to 125,000g/mol.

Especially, in one embodiment, the weight average molecular weight Mw of copolymer of the invention can 10,000 to 75, In the range of 000g/mol, preferably 10,000 to 25,000g/mol, more preferably 10,000 to 18,000g/mol, also, it is described Monomer preferably exists with following amount：The weight % of vinyl acetate 35 to 50 weight %, particularly 38 weight % to 48 weights Measure %, preferably 40 weight % to 45 weight %；The weight % of (methyl) acrylic monomer 25 of logical formula (I) is to 55 weight %, spy It is not 30 weight % to 50 weight %, preferably 35 weight % to 45 weight %, particularly preferred 35 weight % to 40 weight %；Ethene 5 weight % to 25 weight %, particularly 10 weight % to 25 weight %, preferably 15 weight % to 23 weight %；It is wherein described common Polymers is free of acrylic acid.In another embodiment, the weight average molecular weight Mw of copolymer of the invention can 125,000 to In the range of 250,000g/mol.

In still another embodiment, the weight average molecular weight Mw of copolymer of the invention can 250,000 to 1,500, In the range of 000g/mol, wherein in the first embodiment, the weight average molecular weight Mw of present copolymer can 250,000 to In the range of 750,000g/mol, and it is in this second embodiment 750,000 to 1,500,000g/mol, preferably 1,000, 000 to 1,500,000g/mol, more preferably 1,150,000 to 1,450,000g/mol.

Especially, in one embodiment, the weight average molecular weight Mw of copolymer of the invention can 750,000 to 1, In the range of 500,000g/mol, preferably 1,000,000 to 1,500,000g/mol and more preferably 1,150,000 to Isosorbide-5-Nitrae 50, 000g/mol, and the monomer is preferably with following amount presence：The weight % of vinyl acetate 35 to 50 weight %, particularly 38 weight % to 48 weight %, preferably 40 weight % are to 45 weight %；The weight % of (methyl) acrylic monomer 25 of logical formula (I) To 55 weight %, particularly 30 weight % to 50 weight %, preferably 35 weight % to 45 weight %, particularly preferred 35 weight % extremely 40 weight %；The weight % of ethene 5 to 25 weight %, particularly 10 weight % to 25 weight %, preferably 15 weight % to 23 weights Measure %；Wherein described copolymer is free of acrylic acid.

In still another embodiment, the weight average molecular weight Mw of copolymer of the invention can 1,500,000 to 10, In the range of 000,000g/mol, wherein in the first embodiment, the weight average molecular weight Mw of present copolymer can 1, In the range of 500,000 to 5,550,000g/mol, preferably 1,500,000 to 3,000,000g/mol and more preferably 1,500, 000 to 2,000,000g/mol；And it is in this second embodiment 5,500,000 to 10,000,000g/mol.

Especially, in one embodiment, the weight average molecular weight Mw of copolymer of the invention can 1,500,000 to In the range of 5,550,000g/mol, preferably 1,500,000 to 3,000,000g/mol and more preferably 1,500,000 to 2, 000,000g/mol, and the monomer is preferably with following amount presence：The weight % of vinyl acetate 35 is to 50 weight %, spy It is not 38 weight % to 48 weight %, preferably 40 weight % to 45 weight %；The weight of (methyl) acrylic monomer 25 of logical formula (I) Measure % to 55 weight %, particularly 30 weight % to 50 weight %, preferably 35 weight % to 45 weight %, particularly preferred 35 weight Measure % to 40 weight %；The weight % of ethene 5 to 25 weight %, particularly 10 weight % to 25 weight %, preferably 15 weight % are extremely 23 weight %；Wherein described copolymer is free of acrylic acid.

Preferably, in above paragraph, (methyl) acrylic monomer is ethylhexyl acrylate.

The weight average molecular weight Mw can be by gel permeation chromatography (GPC), using trichloro-benzenes as solvent and with polyphenyl second Alkene is determined as reference material.

In a preferred embodiment, weight average molecular weight Mw uses dichloromethane by gel permeation chromatography (GPC) Alkane is determined as eluent and polystyrene as reference material.

Originated by dispersion, GPC samples are preferably by being carried out as follows preparation：Dispersion is dried into (such as 1g with sodium sulphate Dispersion/20g sodium sulphate), gained mixture is ground and Soxhlet extractions 6 hours are carried out to the mixture with chloroform.Extraction Liquid is dried over sodium sulfate, filters and removes solvent (preferably under reduced pressure).Residue is used for GPC.

Preferably, copolymer of the invention is the copolymerization at the peak with the parenchyma peak at 140,000 ± 20,000g/mol Thing (GPC dichloromethane, polystyrene standards, flow velocity 1.0ml/min, volume injected 100 μ l (microlitre), T=30 DEG C).

It is highly preferred that the parenchyma peak include more than 70% (F [%]) polymer quality, more preferably more than 75%, most Preferably more than 80%.

It is further preferred that the polydispersity (D=Mw/Mn) of the copolymer is in the range of 50 to 150, preferably 80 to 120.

In a most preferred embodiment, the weight average molecular weight Mw of copolymer of the invention can 200,000 to In the range of 280,000g/mol, and there is the weight % of vinyl acetate 38 to 48 weight %, lead to (methyl) propylene of formula (I) The weight % of acrylic monomer 35 to 40 weight %；And the weight % of ethene 15 to 23 weight %；Wherein, the copolymer is free of propylene Acid, and the copolymer has peak (the GPC dichloromethane, polystyrene at the parenchyma peak at 140,000 ± 20,000g/mol Reference material, flow velocity 1.0ml/min, volume injected 100 μ l (microlitre), T=30 DEG C).

In the most preferred embodiment further, the parenchyma peak includes the polymeric material more than 80% (F [%]) Amount, and copolymer polydispersity (D=Mw/Mn) in the range of 80 to 120.

In the preferred embodiment of a replacement, the weight average molecular weight Mw of copolymer of the invention can be 125,000 To 250,000g/mol, and there is the weight % of vinyl acetate 38 to 48 weight %, lead to (methyl) third of formula (I) The weight % of alkene acrylic monomer 35 to 40 weight %；And the weight % of ethene 15 to 23 weight %；Wherein, the copolymer is free of third Olefin(e) acid, and the copolymer has peak (the GPC dichloromethane, polyphenyl second at the parenchyma peak at 140,000 ± 20,000g/mol Alkene reference material, flow velocity 1.0ml/min, volume injected 100 μ l (microlitre), T=30 DEG C).

The solids content of the dispersion may be, for example, 30 weight % to 80 weight %, particularly 50 weight % to 70 weights %, preferably 55 weight % to 65 weight % is measured, the solids content measures 30 points according to DIN EN ISO 3251 at 130 DEG C Clock.When using the dispersion with this solids content, it is preferable that dispersion is coated relative to the whole comprising agricultural chemicals The dosage of preparation is 1 weight % to 20 weight %, most preferably more preferably 2 weight % to 15 weight %, 3 weight % to 12 weights Measure %.

The pH value of the dispersion can for 4 to 7, particularly 4.5 to 6.5, the pH value according to DIN ISO 976, with The 1 of water:Measured in 1 mixture.The dispersion can show 0.1 to 5 μm, particularly 0.2 to 2.0 μm of particle mean size.It is flat Equal granularity d50 is following size, i.e., respectively account for 50wt% larger and smaller than the size.It can be measured by using ultracentrifuge (W.Scholtan,H.Lange,Kolloid,Z.und Z.Polymere 250(1972),782-796)。

In order to improve filming performance, it is advantageous to the minimum film forming temperature that the dispersion is measured according to DIN ISO 2115 Spend for 0 DEG C.

According to another preferred embodiment of the present invention, the dispersion most not plasticizer-containing and/or nonionic Detergent, is particularly free of alkylphenol ethoxylate mostly.This is favourable, because the copolymer of the present invention can be with water base point The form of granular media is provided without adding the foregoing additive for causing environmental problem.For nonionic detergent, especially alkane It is especially true for base phenol ethoxylate.

For the present invention, any agricultural chemicals can be used to be used to provide coating.Therefore, agricultural chemicals may be selected from Insecticide, fungicide, bactericide, virucide, acaricide, molluscacide, nematicide, ovicide, expelling parasite Agent, rat-bane, herbicide, safener, fertilizer, biological agent, or their mixture.

The agricultural chemicals, or hereinafter also referred to " active component " (" a.i. "), herein with its " adopted name " To refer to, its for it is known and be recorded in such as Pesticide Manual (" The Pesticide Manual ", the 14th edition, British Crop Protection Council 2006) in, or can be in internet (such as http:// Www.alanwood.net/pesticides searched in).

In the presence of compound (A) or compound (B) can be with tautomeric forms, this compound above and Hereinafter it is interpreted as also including (if being applicable) corresponding tautomeric form, even if it is not specific in every case Refer to.

1) ergosterol biosynthesis inhibitor, for example：(1.1) cartap (aldimorph), (1.2) oxygen ring azoles (azaconazole), (1.3) Bitertanol (bitertanol), (1.4) bromuconazole (bromuconazole), (1.5) ring Azoles alcohol (cyproconazole), (1.6) diclobutrazol (diclobutrazole), (1.7) Difenoconazole (difenoconazole), (1.8) olefin conversion (diniconazole), (1.9) olefin conversion-M (diniconazole-M), (1.10) dodemorph (dodemorph), (1.11) dodemorph acetate (dodemorph acetate), (1.12) Epoxiconazole (epoxiconazole), (1.13) etaconazole (etaconazole), (1.14) Fenarimol (fenarimol), (1.15) RH-7592 (fenbuconazole), (1.16) fenhexamid (fenhexamid), (1.17) fenpropidin (fenpropidin), (1.18) butadiene morpholine (fenpropimorph), (1.19) Fluquinconazole (fluquinconazole), (1.20) flurprimidol (flurprimidol), (1.21) Flusilazole (flusilazole), (1.22) Flutriafol (flutriafol), (1.23) furconazole (furconazole), (1.24) are along furconazole_cis (furconazole-cis), (1.25) Hexaconazole (hexaconazole), (1.26) imazalil (imazalil), (1.27) Imazalil sulfate (imazalil Sulfate), (1.28) glyoxalin (imibenconazole), (1.29) kind bacterium azoles (ipconazole), (1.30) metconazole (metconazole), (1.31) nitrile bacterium azoles (myclobutanil), (1.32) Naftifine (naftifine), (1.33) fluorobenzene are phonetic Pyridine alcohol (nuarimol), (1.34) Evil imidazoles (oxpoconazole), (1.35) paclobutrazol (paclobutrazol), (1.36) Pefurazoate (pefurazoate), (1.37) penconazole (penconazole), (1.38) disease spend clever (piperalin), (1.39) Prochloraz (prochloraz), (1.40) propiconazole (propiconazole), (1.41) prothioconazoles (prothioconazole), (1.42) pyributicarb (pyributicarb), (1.43) pyrifenox (pyrifenox), (1.44) quinoline Azoles (quinconazole), (1.45) simeconazoles (simeconazole), (1.46) volution bacterium amine (spiroxamine), (1.47) Tebuconazole (tebuconazole), (1.48) Terbinafine (terbinafine), (1.49) tetraconazole (tetraconazole), (1.50) triazolone (triadimefon), (1.51) Triadimenol (triadimenol), (1.52) ten Morpholine (tridemorph), (1.53) fluorine bacterium azoles (triflumizole), (1.54) triforine (triforine), (1.55) Triticonazole (triticonazole), (1.56) uniconazole P (uniconazole), (1.57) uniconazole P-p (uniconazole- P), (1.58) croconazole (viniconazole), (1.59) voriconazole (voriconazole), (1.60) 1- (4- chlorobenzenes Base) -2- (1H-1,2,4- triazol-1-yls) suberol, (1.61) 1- (2,2- dimethyl -2,3- dihydro -1H- indenes -1- bases) -1H- Imidazoles -5- methyl formates, (1.62) N'- { 5- (difluoromethyl) -2- methyl -4- [3- (trimethyl silyl) propoxyl group] benzene Base }-N- ethyl-N-methyls carbonamidine, (1.63) N- ethyl-N-methyls-N'- { 2- methyl -5- (trifluoromethyl) -4- [3- (front threes Base silicyl) propoxyl group] phenyl carbonamidine, (1.64) O- [1- (4- methoxyphenoxies) -3,3- dimethyl butyrate -2- bases] 1H- Imidazoles -1- thiocarboxylics, (1.65) SYP-Z048s (pyrisoxazole).

2) complex I or II respiratory chain inhibitor, for example：(2.1) biphenyl pyrrole bacterium amine (bixafen), (2.2) pyridine acyl bacterium Amine (boscalid), (2.3) carboxin (carboxin), (2.4) fluorine mepanipyrim (diflumetorim), (2.5) fenfuram (fenfuram), (2.6) fluopyram (fluopyram), (2.7) flutolanil (flutolanil), (2.8) fluxapyroxad (fluxapyroxad), (2.9) furametpyr (furametpyr), (2.10) seed dressing amine (furmecyclox), (2.11) pyrazoles Naphthalene bacterium amine (isopyrazam) (cis epimerism racemic modification 1RS, 4SR, 9RS and trans epimerism racemic modification 1RS, 4SR, 9SR mixture), (2.12) isopyrazam (trans epimerism racemic modification 1RS, 4SR, 9SR), (2.13) pyrazoles Naphthalene bacterium amine (trans epimerism correspondence isomers 1R, 4S, 9S), (2.14) isopyrazam (trans epimerism correspondence isomery Body 1S, 4R, 9R), (2.15) isopyrazam (cis epimerism racemic modification 1RS, 4SR, 9RS), (2.16) pyrazole naphthalene bacteria Amine (cis epimerism correspondence isomers 1R, 4S, 9R), (2.17) isopyrazam (cis epimerism correspondence isomers 1S, 4R, 9S), (2.18) mebenil (mepronil), (2.19) oxycarboxin (oxycarboxin), (2.20) fluorine azoles bacterium aniline (penflufen), (2.21) pyrrole metsulfovax (penthiopyrad), (2.22) fluorine azoles ring bacterium amine (sedaxane), (2.23) thiophene Fluorine bacterium amine (thifluzamide), (2.24) 1- methyl-N- [2- (1,1,2,2- tetrafluoros ethyoxyl) phenyl] -3- (fluoroforms Base) -1H- pyrazole-4-carboxamides, (2.25) 3- (difluoromethyl) -1- methyl-N- [2- (1,1,2,2- tetrafluoros ethyoxyl) benzene Base] -1H- pyrazole-4-carboxamides, (2.26) 3- (difluoromethyl)-N- [the fluoro- 2- of 4- (1,1,2,3,3,3- hexafluoros propoxyl group) benzene Base] -1- methyl isophthalic acid H- pyrazole-4-carboxamides, (2.27) N- [1- (2,4 dichloro benzene base) -1- methoxy propyl -2- bases] -3- (two Methyl fluoride) -1- methyl isophthalic acid H- pyrazole-4-carboxamides, the fluoro- N- of (2.28) 5,8- bis- [2- (the fluoro- 4- of 2- { [4- (trifluoromethyl) pyrroles Pyridine -2- bases] epoxide phenyl) ethyl] quinazoline -4- amine, (2.29) benzo alkene fluorine bacterium azoles (benzovindiflupyr), (2.30) N- [(1S, 4R) -9- (dichloromethylene) -1,2,3,4- tetrahydrochysene -1,4- methanonaphthalene -5- bases] -3- (difluoromethyl) - 1- methyl isophthalic acid H- pyrazole-4-carboxamides, (2.31) N- [(1R, 4S) -9- (dichloromethylene) -1,2,3,4- tetrahydrochysene -1,4- methylenes Base naphthalene -5- bases] -3- (difluoromethyl) -1- methyl isophthalic acid H- pyrazole-4-carboxamides, (2.32) 3- (difluoromethyl) -1- methyl-N- (the fluoro- 1H- indenes -4- bases of 1,1,3- trimethyls -2,3- two) -1H- pyrazole-4-carboxamides, (2.33) 1,3,5- trimethyls-N- (1, 1,3- trimethyl -2,3- dihydro -1H- indenes -4- bases) -1H- pyrazole-4-carboxamides, (2.34) 1- methyl -3- (trifluoromethyl)-N- (1,1,3- trimethyl -2,3- dihydro -1H- indenes -4- bases) -1H- pyrazole-4-carboxamides, (2.35) 1- methyl -3- (fluoroforms Base)-N- [(3R) -1,1,3- trimethyl -2,3- dihydro -1H- indenes -4- bases] -1H- pyrazole-4-carboxamides, (2.36) 1- methyl - 3- (trifluoromethyl)-N- [(3S) -1,1,3- trimethyl -2,3- dihydro -1H- indenes -4- bases] -1H- pyrazole-4-carboxamides, (2.37) 3- (difluoromethyl) -1- methyl-N- [(3S) -1,1,3- trimethyl -2,3- dihydro -1H- indenes -4- bases] -1H- pyrazoles - 4- formamides, (2.38) 3- (difluoromethyl) -1- methyl-N- [(3R) -1,1,3- trimethyl -2,3- dihydro -1H- indenes -4- bases] - 1H- pyrazole-4-carboxamides, (2.39) 1,3,5- trimethyls-N- [(3R) -1,1,3- trimethyl -2,3- dihydro -1H- indenes -4- Base] -1H- pyrazole-4-carboxamides, (2.40) 1,3,5- trimethyls-N- [(3S) -1,1,3- trimethyl -2,3- dihydro -1H- indenes - 4- yls] -1H- pyrazole-4-carboxamides, (2.41) benodanil (benodanil), the chloro- N- of (2.42) 2- (1,1,3- trimethyl -2, 3- dihydro -1H- indenes -4- bases) pyridine-3-carboxamide, (2.43) isopropyl metsulfovax (isofetamid).

3) complex III respiratory chain inhibitor, for example：(3.1) azoles mepanipyrim (ametoctradin), (3.2) peace are beautiful Fast (amisulbrom), (3.3) Fluoxastrobin (azoxystrobin), (3.4) cyazofamid (cyazofamid), (3.5) first fragrant bacterium Ester (coumethoxystrobin), (3.6) SYP-3375 (coumoxystrobin), (3.7) dimoxystrobin (dimoxystrobin), (3.8) Enestroburin (enoxastrobin), (3.9) famoxadones (famoxadone), (3.10) Fenamidone (fenamidone), (3.11) fluorine bacterium mite ester (flufenoxystrobin), (3.12) fluoxastrobin (fluoxastrobin), (3.13) kresoxim-methyl (kresoxim-methyl), (3.14) SSF 126 (metominostrobin), (3.15) orysastrobin (orysastrobin), (3.16) ZEN 90160 (picoxystrobin), (3.17) pyraclostrobin (pyraclostrobin), (3.18) azoles amine bacterium ester (pyrametostrobin), (3.19) azoles amine bacterium ester (pyraoxystrobin), (3.20) pyrrole bacterium benzene prestige (pyribencarb), (3.21) chlorine nalidixic bacterium ester (triclopyricarb), (3.22) ({ [6- (3- chloro-2-methyls phenoxy group) -5- fluorine is phonetic by 2- by trifloxystrobin (trifloxystrobin), (3.23) (2E) -2- Pyridine -4- bases] epoxide phenyl) -2- (methoxyimino)-N- methylacetamides, (3.24) (2E) -2- (methoxyimino) - N- methyl -2- (2- { [({ (1E) -1- [3- (trifluoromethyl) phenyl] ethylidene } amino) epoxide] methyl } phenyl) acetamide, (3.25) (2E) -2- (methoxyimino)-N- methyl -2- { 2- [(E)-({ 1- [3- (trifluoromethyl) phenyl] ethyoxyl } Asias Amino) methyl] phenyl acetamide, (3.26) (2E) -2- { 2- [({ [(1E) -1- (3- { [the fluoro- 2- phenyl vinyls of (E) -1-] Epoxide } phenyl) ethylidene] amino epoxide) methyl] phenyl -2- (methoxyimino)-N- methylacetamides, (3.27) alkene Oxime bacterium amine (Fenaminostrobin), (3.28) 5- methoxyl group -2- methyl -4- (2- { [({ (1E) -1- [3- (trifluoromethyl) benzene Base] ethylidene amino) epoxide] methyl phenyl) -2,4- dihydro -3H-1,2,4- triazole -3- ketone, (3.29) (2E) -2- { 2- [({ cyclopropyl [(4- methoxyphenyls) imino group] methyl } sulfanyl) methyl] phenyl } -3- methoxy-methyl acrylates, (3.30) N- (3- ethyl -3,5,5- trimethylcyclohexyls) -3- formamidos -2-Hydroxylbenzamide, (3.31) 2- 2- [(2, 5- dimethyl phenoxies) methyl] phenyl -2- methoxy N-methylacetamides, (3.32) 2- { 2- [(2,5- dimethyl benzene oxygen Base) methyl] phenyl } -2- methoxy N-methylacetamides.

4) mitosis and cell division inhibitor, for example：(4.1) benomyl (benomyl), (4.2) carbendazim (carbendazim), (4.3) chlorfenazole, (4.4) diethofencarb (diethofencarb), (4.5) Guardian (ethaboxam), (4.6) fluopicolide (fluopicolide), (4.7) furidazol (fuberidazole), (4.8) penta bacterium Grand (pencycuron), (4.9) probenazole (thiabendazole), (4.10) thiophanate-methyl (thiophanate- Methyl), (4.11) thiophanate (thiophanate), (4.12) zoxamide (zoxamide), (4.13) 5- chloro- 7- (4- first Phenylpiperidines -1- bases) -6- (2,4,6- trifluorophenyls) [1,2,4] triazol [1,5-a] pyrimidine, (4.14) 3- chloro- 5- (6- chlorine pyrroles Pyridine -3- bases) -6- methyl -4- (2,4,6- trifluorophenyls) pyridazine.

5) there can be the compound that many sites are acted on, for example：(5.1) Bordeaux mixture, (5.2) difoltan (captafol), (5.3) captan (captan), (5.4) Bravo (chlorothalonil), (5.5) Kocide SD (copper hydroxide), (5.6) copper naphthenate (copper naphthenate), (5.7) cupric oxide (copper Oxide), (5.8) COPPER OXYCHLORIDE 37,5 (copper oxychloride), (5.9) copper sulphate (2+) (copper (2+) sulfate), (5.10) dichlofluanid (dichlofluanid), (5.11) dithianon (dithianon), (5.12) dodine (dodine), (5.13) dodine free alkali, (5.14) fervam (ferbam), (5.15) fluorine folpet (fluorofolpet), (5.16) are gone out Bacterium pellet (folpet), the pungent salt of (5.17) biguanides (guazatine), (5.18) guazatine acetate (guazatine acetate), (5.19) iminoctadine (iminoctadine), (5.20) biguanides octyl benzene sulfonate (iminoctadine Albesilate), (5.21) iminoctadine triacetate (iminoctadine triacetate), (5.22) mancopper (mancopper), (5.23) Mancozeb (mancozeb), (5.24) maneb (maneb), (5.25) Carbatene (metiram), (5.26) Carbatene zinc (metiram zinc), (5.27) copper 8-hydroxyquinolinate (oxine-copper), (5.28) propane Amidine (propamidine), (5.29) Propineb (propineb), (5.30) sulphur and sulphur product (including calcium polysulfide), (5.31) Thiram (thiram), (5.32) Tolylfluanid (tolylfluanid), (5.33) zineb (zineb), (5.34) Fu Mei Zinc (ziram), (5.35) anilazine (anilazine).

6) compound of host defense can be induced, for example：(6.1) my acid benzene-S-methyl (acibenzolar-S- Methyl), (6.2) isotianil (isotianil), (6.3) probenazole (probenazole), (6.4) tiadinil (tiadinil), (6.5) laminarin (laminarin).

7) amino acid and/or inhibition of protein biosynthesis agent, for example：(7.1) andoprim, (7.2) blasticidin-S (blasticidin-S), (7.3) cyprodinil (cyprodinil), (7.4) kasugarnycin (kasugamycin), (7.5) spring Thunder mycin hydrochloride hydrate (kasugamycin hydrochloride hydrate), (7.6) mepanipyrim (mepanipyrim), (7.7) pyrimethanil (pyrimethanil), (7.8) 3- (fluoro- 3,3,4,4- tetramethyls -3,4- dihydros of 5- Isoquinolyl-1) quinoline, (7.9) terramycin (oxytetracycline), (7.10) streptomysin (streptomycin).

8) ATP produces inhibitor, for example：(8.1) fentin acetate (fentin acetate), (8.2) triphenyl chlorine Change tin (fentin chloride), (8.3) triphenyl tin hydroxide (fentin hydroxide), (8.4) Silthiopham (silthiofam)。

9) Cell wall synthesis inhibitor, for example：(9.1) benzene metsulfovax (benthiavalicarb), (9.2) dimethomorph (dimethomorph), (9.3) flumorph (flumorph), (9.4) iprovalicarb (iprovalicarb), (9.5) double alkynes acyls Bacterium amine (mandipropamid), (9.6) polyoxin (polyoxin), (9.7) Polyoxin (polyoxorim), (9.8) have Validamycin A (validamycin A), (9.9) figured silk fabrics bacterium amine (valifenalate), (9.10) polyoxin B (polyoxin B).

10) lipid and film synthetic inhibitor, for example：(10.1) biphenyl, (10.2) chloroneb (chloroneb), (10.3) Chlorine ammonium nitrate (dicloran), (10.4) edifenphos (edifenphos), (10.5) Grandox fumigant (etridiazole), (10.6) Iodocarb, (10.7) different rice blast net (iprobenfos), (10.8) Isoprothiolane (isoprothiolane), (10.9) Propamocarb (propamocarb), (10.10) propamocarb (propamocarb hydrochloride), (10.11) prothiocarb (prothiocarb), (10.12) pyrazophos (pyrazophos), (10.13) pentachloronitrobenzene (quintozene), (10.14) Tecnazene (tecnazene), (10.15) tolelofos-methyl (tolclofos-methyl).

11) melanin biosynthesis inhibitor, for example：(11.1) ring propionyl bacterium amine (carpropamid), (11.2) double chlorine Zarilamid (diclocymet), (11.3) zarilamid (fenoxanil), (11.4) phthalide (phthalide), (11.5) pyroquilon (pyroquilon), (11.6) tricyclazole (tricyclazole), (11.7) { 3- methyl isophthalic acids-[(4- methyl benzoyls) ammonia Base] butyl- 2- yls } carbamic acid 2,2,2- trifluoro ethyl esters.

12) nucleic acid synthetic inhibitor, for example：(12.1) M 9834 (benalaxyl), (12.2) smart M 9834 (benalaxyl-M (kiralaxyl)), (12.3) bupirimate (bupirimate), (12.4) clozylacon, (12.5) dimethirimol (dimethirimol), (12.6) ethirimol (ethirimol), (12.7) furalaxyl (furalaxyl), (12.8) hymexazol (hymexazol), (12.9) metalaxyl (metalaxyl), (12.10) Metalaxyl-M (metalaxyl-M (mefenoxam)), (12.11) ofurace (ofurace), (12.12) Evil frosts clever (oxadixyl), (12.13) oxolinic acids (oxolinic acid), (12.14) octhilinone (octhilinone).

13) signal transduction inhibitor, for example：(13.1) chlozolinate (chlozolinate), (13.2) fenpiclonil (fenpiclonil), (13.3) fludioxonil (fludioxonil), (13.4) iprodione (iprodione), (13.5) procymidone (procymidone), (13.6) quinoxyfen (quinoxyfen), (13.7) vinclozolin (vinclozolin), (13.8) The third oxygen quinoline (proquinazid).

14) compound of uncoupler is can act as, for example：(14.1) binapacryl (binapacryl), (14.2) chlorfenethol General (dinocap), (14.3) ferimzone (ferimzone), (14.4) fluazinam (fluazinam), (14.5) mite that disappears are more (meptyldinocap)。

15) other compounds, for example：(15.1) benthiozole (benthiazole), (15.2) bethoxazin, (15.3) capsimycin (capsimycin), (15.4) carvol (carvone), (15.5) chinomethionat (chinomethionat), (15.6) pyriofenone (chlazafenone), (15.7) cufraneb (cufraneb), (15.8) cyflufenamid (cyflufenamid), (15.9) cymoxanil (cymoxanil), (15.10) cyclopropyl-sulfonylamide (cyprosulfamide), (15.11) dazomet (dazomet), (15.12) debacarb (debacarb), (15.13) antiphen (dichlorophen), (15.14) diclomezin (diclomezine), (15.15) difenzoquat (difenzoquat), (15.16) Difenzoquat Methylsulfate (difenzoquat metilsulfate), (15.17) diphenylamines, (15.18) ecomate, (15.19) amine benzene pyrrole bacterium ketone (fenpyrazamine), (15.20) fluorine acyl bacterium amine (flumetover), (15.21) fluorine acid imide (fluoroimide), (15.22) flusulfamide (flusulfamide), (15.23) flutianil, (15.24) fosetyl aluminium (fosetyl-aluminium), (15.25) ethyl phosphine calcium (fosetyl-calcium), (15.26) ethyl phosphine sodium (fosetyl- Sodium), (15.27) hexachloro-benzene, (15.28) irumamycin, (15.29) methasulfocarb (methasulfocarb), (15.30) How mould methyl-isorhodanate (methyl isothiocyanate), (15.31) metrafenone (metrafenone), (15.32) rice is Plain (mildiomycin), (15.33) natamycin (natamycin), (15.34) nickel dimethyldithiocarbamate (nickel dimethyldithiocarbamate), (15.35) nitrothalisopropyl (nitrothal-isopropyl), (15.37) Oxamocarb, (15.38) oxyfenthiin, (15.39) pentachlorophenol and its salt, (15.40) phenothrin (phenothrin), (15.41) phosphorous acid and its salt, (15.42) Propamocarb ethyl phosphine hydrochlorate (propamocarb- Fosetylate), (15.43) propanosine-sodium, (15.44) pyrimorph (pyrimorph), (15.45) (2E)- 3- (4- tert-butyl-phenyls) -3- (2- chloropyridine -4- bases) -1- (morpholine -4- bases) propyl- 2- alkene -1- ketone, (15.46) (2Z) -3- (4- tert-butyl-phenyls) -3- (2- chloropyridine -4- bases) -1- (morpholine -4- bases) propyl- 2- alkene -1- ketone, (15.47) pyrrolnitrin (pyrrolnitrine), (15.48) tebufloquin, (15.49) tecloftalam (tecloftalam), (15.50) first flusulfamide (tolnifanide), (15.51) triazoxide (triazoxide), (15.52) trichlamide (trichlamide), (15.53) Zarilamid (zarilamid), (15.54) (3S, 6S, 7R, 8R) -8- benzyls -3- [(3- [(isobutyryl epoxide) methoxyl group] - 4-methoxypyridine -2- bases } carbonyl) amino] -6- methyl -4,9- dioxo -1,5- dioxa nonyl- 7- base 2 Methylpropionic acids ester, (15.55) 1- (4- { 4- [(5R) -5- (2,6- difluorophenyls) -4,5- dihydro -1,2- oxazole -3- bases] -1,3- thiazol-2-yls } Piperidin-1-yl) -2- [5- methyl -3- (trifluoromethyl) -1H- pyrazol-1-yls] ethyl ketone, (15.56) 1- (4- { 4- [(5S) -5- (2,6- difluorophenyls) -4,5- dihydro -1,2- oxazole -3- bases] -1,3- thiazol-2-yls } piperidin-1-yl) -2- [5- methyl -3- (trifluoromethyl) -1H- pyrazol-1-yls] ethyl ketone, (15.57) 1- (4- { 4- [5- (2,6- difluorophenyls) -4,5- dihydro -1,2- Evil Azoles -3- bases] -1,3- thiazol-2-yls } piperidin-1-yl) -2- [5- methyl -3- (trifluoromethyl) -1H- pyrazol-1-yls] ethyl ketone, (15.58) 1- (4- methoxyphenoxies) -3,3- dimethyl butyrates -2- base 1H- imidazoles -1- formic acid esters, (15.59) 2,3,5,6- tetra- Chloro- 4- (methyl sulphonyl) pyridine, (15.60) 2,3- dibutyl -6- chlorothiophenes simultaneously [2,3-d] pyrimidine -4 (3H) -one, (15.61) 2,6- dimethyl -1H, 5H- [1,4] dithiene [2,3-c:5,6-c'] -1,3,5,7 (2H, 6H)-tetrone of two pyrroles, (15.62) 2- [5- methyl -3- (trifluoromethyl) -1H- pyrazol-1-yls] -1- (4- 4- [(5R) -5- phenyl -4,5- dihydro -1, 2- oxazole -3- bases] -1,3- thiazol-2-yls piperidin-1-yl) ethyl ketone, (15.63) 2- [5- methyl -3- (trifluoromethyl) -1H- pyrroles Azoles -1- bases] -1- (4- { 4- [(5S) -5- phenyl -4,5- dihydro -1,2- oxazole -3- bases] -1,3- thiazol-2-yls } piperidines -1- Base) ethyl ketone, (15.64) 2- [5- methyl -3- (trifluoromethyl) -1H- pyrazol-1-yls] -1- 4- [4- (5- phenyl -4,5- dihydros - 1,2- oxazole -3- bases) -1,3- thiazol-2-yls] piperidin-1-yl ethyl ketone, the iodo- 3- propyl group -4H- benzene of (15.65) 2- butoxy -6- And pyrans -4- ketone, the chloro- 5- of (15.66) 2- [the chloro- 1- of 2- (the fluoro- 4- methoxyphenyls of 2,6- bis-) -4- methyl isophthalic acid H- imidazoles -5- Base] pyridine, (15.67) 2- phenylphenols and its salt, (15.68) 3- (fluoro- 3,3- dimethyl -3,4- dihydro isoquinolines of 4,4,5- tri- Quinoline -1- bases) quinoline, (15.69) 3,4,5- trichloropyridine -2,6- dimethoxy nitriles, (15.70) 3- chloro- 5- (4- chlorphenyls) -4- (2, 6- difluorophenyls) -6- methyl pyridazine, (15.71) 4- (4- chlorphenyls) -5- (2,6- difluorophenyls) -3,6- diformazans radical pyridazine, (15.72) 5- amino -1,3,4- thiadiazoles -2- mercaptan, the chloro- N'- phenyl-N'- of (15.73) 5- (propyl- 2- alkynes -1- bases) thiophene - 2- sulfohydrazides, the fluoro- 2- of (15.74) 5- [(4- luorobenzyls) epoxide] pyrimidine -4- amine, the fluoro- 2- of (15.75) 5- [(4- methyl-benzyls) Epoxide] pyrimidine -4- amine, (15.76) 5- methyl -6- octyl groups [1,2,4] triazol [1,5-a] pyrimidine -7- amine, (15.77) (2Z) - 3- amino -2- cyano group -3- ethyl phenylacrylates, (15.78) N'- (4- { [3- (4- chlorobenzyls) -1,2,4- thiadiazoles -5- bases] Epoxide } -2,5- 3,5-dimethylphenyls)-N- ethyl-N-methyls carbonamidine, (15.79) N- (4- chlorobenzyls) -3- [3- methoxyl groups -4- (propyl- 2- alkynes -1- bases epoxide) phenyl] propionamide, (15.80) N- [(4- chlorphenyls) (cyano group) methyl] -3- [3- methoxyl groups -4- (propyl- 2- alkynes -1- bases epoxide) phenyl] propionamide, (15.81) N- [(the bromo- 3- chloropyridines -2- bases of 5-) methyl] -2,4- dichloro cigarettes Acid amides, the chloro-nicotinamides of (15.82) N- [1- (the bromo- 3- chloropyridines -2- bases of 5-) ethyl] -2,4- two, [(5- is bromo- by 1- by (15.83) N- 3- chloropyridine -2- bases) ethyl] the fluoro- 4- iodine niacinamide of -2-, (15.84) N- { (E)-[(cyclo propyl methoxy) imino group] [6- (difluoro-methoxy) -2,3- difluorophenyls] methyl -2- phenyl-acetamides, (15.85) N- { (Z)-[(cyclo propyl methoxy) is sub- Amino] [6- (difluoro-methoxy) -2,3- difluorophenyls] methyl -2- phenyl-acetamides, (15.86) N'- 4- [(the 3- tert-butyl groups - 4- cyano group -1,2- thiazole -5- bases) epoxide] the chloro- 5- aminomethyl phenyls of -2--N- ethyl-N-methyls carbonamidine, (15.87) N- methyl - 2- (1- { [5- methyl -3- (trifluoromethyl) -1H- pyrazol-1-yls] acetyl group } piperidin-4-yl)-N- (1,2,3,4- naphthanes - 1- yls) -1,3- thiazole -4-carboxamides, (15.88) N- methyl -2- (1- { [5- methyl -3- (trifluoromethyl) -1H- pyrazoles -1- Base] acetyl group piperidin-4-yl)-N- [(1R) -1,2,3,4- naphthane -1- bases] -1,3- thiazole -4-carboxamides, (15.89) N- Methyl -2- (1- { [5- methyl -3- (trifluoromethyl) -1H- pyrazol-1-yls] acetyl group } piperidin-4-yl)-N- [(1S) -1,2,3, 4- naphthane -1- bases] -1,3- thiazole -4-carboxamides, (15.90) { [({ [(1- methyl isophthalic acid H- tetrazolium -5- bases) (phenyl) is sub- by 6- Methyl] amino epoxide) methyl] pyridine -2- bases amyl carbamate, (15.91) azophenlyene -1- formic acid, (15.92) 8- hydroxyl quinolines Quinoline, (15.93) 8-hydroxyquinoline sulfuric ester (2:1), (15.94) { 6- [({ [(1- methyl isophthalic acid H- tetrazolium -5- bases) (phenyl) methylenes Base] amino epoxide) methyl] pyridine -2- bases t-butyl carbamate, (15.95) 1- methyl -3- (trifluoromethyl)-N- [2'- (trifluoromethyl) biphenyl -2- bases] -1H- pyrazole-4-carboxamides, (15.96) N- (4'- chlordiphenyl -2- bases) -3- (difluoromethyl) - 1- methyl isophthalic acid H- pyrazole-4-carboxamides, (15.97) N- (2', 4'- dichlorobenzene -2- bases) -3- (difluoromethyl) -1- methyl - 1H- pyrazole-4-carboxamides, (15.98) 3- (difluoromethyl) -1- methyl-N- [4'- (trifluoromethyl) biphenyl -2- bases] -1H- pyrroles Azoles -4- formamides, (15.99) N- (2', 5'- DfBP -2- bases) -1- methyl -3- (trifluoromethyl) -1H- pyrazoles -4- formyls Amine, (15.100) 3- (difluoromethyl) -1- methyl-N- [4'- (propyl- 1- alkynes -1- bases) biphenyl -2- bases] -1H- pyrazoles -4- formyls Amine, the fluoro- 1,3- dimethyl-N -s of (15.101) 5- [4'- (propyl- 1- alkynes -1- bases) biphenyl -2- bases] -1H- pyrazole-4-carboxamides, (15.102) the chloro- N- of 2- [4'- (propyl- 1- alkynes -1- bases) biphenyl -2- bases] niacinamide, (15.103) 3- (difluoromethyl)-N- [4'- (3,3- dimethyl butyrate -1- alkynes -1- bases) biphenyl -2- bases] -1- methyl isophthalic acid H- pyrazole-4-carboxamides, (15.104) N- [4'- (3, 3- dimethyl butyrate -1- alkynes -1- bases) biphenyl -2- bases] the fluoro- 1,3- dimethyl -1H- pyrazole-4-carboxamides of -5-, (15.105) 3- (difluoromethyl)-N- (4'- acetenyl biphenyl -2- bases) -1- methyl isophthalic acid H- pyrazole-4-carboxamides, (15.106) N- (4'- acetylene Base biphenyl -2- bases) the fluoro- 1,3- dimethyl -1H- pyrazole-4-carboxamides of -5-, the chloro- N- of (15.107) 2- (4'- acetenyls biphenyl - 2- yls) niacinamide, the chloro- N- of (15.108) 2- [4'- (3,3- dimethyl butyrate -1- alkynes -1- bases) biphenyl -2- bases] niacinamide, (15.109) 4- (difluoromethyl) -2- methyl-N- [4'- (trifluoromethyl) biphenyl -2- bases] -1,3- thiazole -5- formamides, (15.110) the fluoro- N- of 5- [4'- (3- hydroxy-3-methyl butyl- 1- alkynes -1- bases) biphenyl -2- bases] -1,3- dimethyl -1H- pyrazoles - 4- formamides, the chloro- N- of (15.111) 2- [4'- (3- hydroxy-3-methyl butyl- 1- alkynes -1- bases) biphenyl -2- bases] niacinamide, (15.112) 3- (difluoromethyl)-N- [4'- (3- methoxyl group -3- methyl butyl- 1- alkynes -1- bases) biphenyl -2- bases] -1- methyl isophthalic acids H- Pyrazole-4-carboxamide, the fluoro- N- of (15.113) 5- [4'- (3- methoxyl group -3- methyl butyl- 1- alkynes -1- bases) biphenyl -2- bases] -1,3- Dimethyl -1H- pyrazole-4-carboxamides, the chloro- N- of (15.114) 2- [4'- (3- methoxyl group -3- methyl butyl- 1- alkynes -1- bases) biphenyl - 2- yls] niacinamide, (15.115) (the bromo- 2- methoxyl groups -4- picolines -3- bases of 5-) (2,3,4- trimethoxy -6- methylbenzenes Base) ketone, (15.116) N- [2- (4- { [3- (4- chlorphenyls) propyl- 2- alkene -1- bases] epoxide } -3- methoxyphenyls) ethyl] - N2- (methyl sulphonyl) valine amide, (15.117) 4- oxos -4- [(2- phenylethyls) amino] butyric acid, (15.118) { 6- [({ [(Z)-(1- methyl isophthalic acid H- tetrazolium -5- bases) (phenyl) methylene] amino } epoxide) methyl] pyridine -2- bases } carbamic acid Butyl- 3- alkynes -1- esters, (15.119) 4- amino-5-fluorine pyrimidine -2- alcohol (tautomeric forms：4- amino-5-fluorines pyrimidine -2 (1H) - Ketone), (15.120) Propylgallate, (15.121) 1,3- dimethyl-N -s (1,1,3- trimethyls -2,3- two Hydrogen -1H- indenes -4- bases) -1H- pyrazole-4-carboxamides, (15.122) 1,3- dimethyl-N -s [(3R) -1,1,3- trimethyls -2,3- Dihydro -1H- indenes -4- bases] -1H- pyrazole-4-carboxamides, (15.123) 1,3- dimethyl-N -s [(3S) -1,1,3- trimethyl -2, 3- dihydro -1H- indenes -4- bases] -1H- pyrazole-4-carboxamides, (15.124) [3- (the chloro- 2- fluorophenyls of 4-) -5- (2,4 difluorobenzenes Base) -1,2- oxazole -4- bases] (pyridin-3-yl) methanol, (15.125) (S)-[3- (the chloro- 2- fluorophenyls of 4-) -5- (2,4- difluoros Phenyl) -1,2- oxazole -4- bases] (pyridin-3-yl) methanol, (15.126) (R)-[3- (the chloro- 2- fluorophenyls of 4-) -5- (2,4- bis- Fluorophenyl) -1,2- oxazole -4- bases] (pyridin-3-yl) methanol, (15.127) 2- { [3- (2- chlorphenyls) -2- (2,4 difluorobenzenes Base) oxirane -2- bases] methyl -2,4- dihydro -3H-1,2,4- triazole -3- thioketones, (15.128) 1- { [3- (2- chlorobenzenes Base) -2- (2,4 difluorobenzene base) oxirane -2- bases] methyl -1H-1,2,4- triazole -5- bases thiocyanates, (15.129) 5- (allylsulfanyl) -1- { [3- (2- chlorphenyls) -2- (2,4 difluorobenzene base) oxirane -2- bases] methyl } -1H-1,2,4- Triazole, (15.130) 2- [1- (2,4 dichloro benzene base) -5- hydroxyl -2,6,6- trimethyl hept- 4- yls] -2,4- dihydro -3H-1,2, 4- triazole -3- thioketones, (15.131) 2- { [rel (2R, 3S) -3- (2- chlorphenyls) -2- (2,4 difluorobenzene base) oxirane -2- Base] methyl -2,4- dihydro -3H-1,2,4- triazole -3- thioketones, (15.132) 2- { [rel (2R, 3R) -3- (2- chlorphenyls) -2- (2,4 difluorobenzene base) oxirane -2- bases] methyl -2,4- dihydro -3H-1,2,4- triazole -3- thioketones, (15.133) 1- { [rel (2R, 3S) -3- (2- chlorphenyls) -2- (2,4 difluorobenzene base) oxirane -2- bases] methyl } -1H-1,2,4- triazoles - 5- bases thiocyanates, (15.134) 1- { [rel (2R, 3R) -3- (2- chlorphenyls) -2- (2,4 difluorobenzene base) oxirane -2- Base] methyl -1H-1,2,4- triazole -5- bases thiocyanates, (15.135) 5- (allylsulfanyl) -1- [rel (2R, 3S) - 3- (2- chlorphenyls) -2- (2,4 difluorobenzene base) oxirane -2- bases] methyl -1H-1,2,4- triazoles, (15.136) 5- (alkene Propylsulfanyl) -1- { [rel (2R, 3R) -3- (2- chlorphenyls) -2- (2,4 difluorobenzene base) oxirane -2- bases] methyl } - 1H-1,2,4- triazoles, (15.137) 2- [(2S, 4S, 5S) -1- (2,4 dichloro benzene base) -5- hydroxyl -2,6,6- trimethyl hept- 4- Base] -2,4- dihydro -3H-1,2,4- triazole -3- thioketones, (15.138) 2- [(2R, 4S, 5S) -1- (2,4 dichloro benzene base) -5- hydroxyls Base -2,6,6- trimethyl hept- 4- yls] -2,4- dihydro -3H-1,2,4- triazole -3- thioketones, (15.139) 2- [(2R, 4R, 5R) - 1- (2,4 dichloro benzene base) -5- hydroxyl -2,6,6- trimethyl hept- 4- yls] -2,4- dihydro -3H-1,2,4- triazole -3- thioketones, (15.140) 2- [(2S, 4R, 5R) -1- (2,4 dichloro benzene base) -5- hydroxyl -2,6,6- trimethyl hept- 4- yls] -2,4- dihydros - 3H-1,2,4- triazole -3- thioketones, (15.141) 2- [(2S, 4S, 5R) -1- (2,4 dichloro benzene base) -5- hydroxyl -2,6,6- front threes Base hept- 4- yls] -2,4- dihydro -3H-1,2,4- triazole -3- thioketones, (15.142) 2- [(2R, 4S, 5R) -1- (2,4 dichloro benzenes Base) -5- hydroxyl -2,6,6- trimethyl hept- 4- yls] -2,4- dihydro -3H-1,2,4- triazole -3- thioketones, (15.143) 2- [(2R, 4R, 5S) -1- (2,4 dichloro benzene base) -5- hydroxyl -2,6,6- trimethyl hept- 4- yls] -2,4- dihydro -3H-1,2,4- triazoles -3- Thioketones, (15.144) 2- [(2S, 4R, 5S) -1- (2,4 dichloro benzene base) -5- hydroxyl -2,6,6- trimethyl hept- 4- yls] -2,4- Dihydro -3H-1,2,4- triazole -3- thioketones, (15.145) 2- fluoro- 6- (trifluoromethyl)-N- (1,1,3- trimethyl -2,3- dihydros - 1H- indenes -4- bases) benzamide, (15.146) 2- (6- benzyl pyridine -2- bases) quinazoline, (15.147) 2- [6- (fluoro- 4- first of 3- Phenyl) -5- picoline -2- bases] quinazoline, (15.148) 3- (fluoro- 3,3- dimethyl -3,4- dihydro isoquinolines of 4,4- bis- Quinoline -1- bases) quinoline, (15.149) abscisic acid, (15.150) 3- (difluoromethyl)-N- methoxyl group -1- methyl-N- [1- (2,4,6- Trichlorophenyl) propyl- 2- yls] -1H- pyrazole-4-carboxamides, (15.151) N'- [the bromo- 6- of 5- (2,3- dihydro -1H- indenes -2- base oxygen Base) -2- picoline -3- bases]-N- ethyl-N-methyls carbonamidine, (15.152) N'- { the bromo- 6- of 5- [1- (3,5- difluorophenyls) second Epoxide] -2- picoline -3- bases-N- ethyl-N-methyls carbonamidine, (15.153) N'- { the bromo- 6- of 5- [(1R) -1- (3,5- difluoros Phenyl) ethyoxyl] -2- picoline -3- bases-N- ethyl-N-methyls carbonamidine, (15.154) N'- { the bromo- 6- of 5- [(1S) -1- (3,5- difluorophenyls) ethyoxyl] -2- picoline -3- bases-N- ethyl-N-methyls carbonamidine, (15.155) N'- { bromo- 6- of 5- [(cis- 4- isopropylcyclohexyls) epoxide] -2- picoline -3- bases }-N- ethyl-N-methyls carbonamidine, (15.156) N'- { 5- Bromo- 6- [(trans-4-isopropyl cyclohexyl) epoxide] -2- picoline -3- bases }-N- ethyl-N-methyls carbonamidine, (15.157) N- Cyclopropyl -3- (difluoromethyl) -5- fluoro- N- (2- isopropyl benzyls) -1- methyl isophthalic acid H- pyrazole-4-carboxamides, (15.158) N- The fluoro- 1- methyl isophthalic acids H- pyrazole-4-carboxamides of cyclopropyl-N- (2- cyclopropyl benzyl) -3- (difluoromethyl) -5-, (15.159) N- The fluoro- 1- methyl isophthalic acids H- pyrazole-4-carboxamides of (2- t-butylbenzyls)-N- cyclopropyl -3- (difluoromethyl) -5-, (15.160) N- The fluoro- 1- methyl isophthalic acids H- pyrazole-4-carboxamides of (the chloro- 2- Ethylbenzyls of 5-)-N- cyclopropyl -3- (difluoromethyl) -5-, (15.161) The fluoro- 1- methyl isophthalic acids H- pyrazole-4-carboxamides of N- (5- chloro-2-isopropyls benzyl)-N- cyclopropyl -3- (difluoromethyl) -5-, (15.162) the fluoro- 1- methyl isophthalic acids H- pyrazoles -4- formyls of N- cyclopropyl -3- (difluoromethyl)-N- (2- ethyl -5- luorobenzyls) -5- Amine, the fluoro- N- of (15.163) N- cyclopropyl -3- (difluoromethyl) -5- (the fluoro- 2- isopropyl benzyls of 5-) -1- methyl isophthalic acid H- pyrazoles -4- Formamide, the fluoro- 1- methyl isophthalic acids H- pyrroles of (15.164) N- cyclopropyl-N- (2- cyclopropyl -5- luorobenzyls) -3- (difluoromethyl) -5- Azoles -4- formamides, the fluoro- 1- methyl of (15.165) N- (2- cyclopenta -5- luorobenzyls)-N- cyclopropyl -3- (difluoromethyl) -5- - 1H- pyrazole-4-carboxamides, the fluoro- N- of (15.166) N- cyclopropyl -3- (difluoromethyl) -5- (the fluoro- 6- isopropyl benzyls of 2-) -1- Methyl isophthalic acid H- pyrazole-4-carboxamides, (15.167) N- cyclopropyl -3- (difluoromethyl)-N- (2- ethyl -5- methyl-benzyls) -5- Fluoro- 1- methyl isophthalic acids H- pyrazole-4-carboxamides, the fluoro- N- of (15.168) N- cyclopropyl -3- (difluoromethyl) -5- (2- isopropyls -5- Methyl-benzyl) -1- methyl isophthalic acid H- pyrazole-4-carboxamides, (15.169) N- cyclopropyl-N- (2- cyclopropyl -5- methyl-benzyls) -3- The fluoro- 1- methyl isophthalic acids H- pyrazole-4-carboxamides of (difluoromethyl) -5-, (15.170) N- (the 2- tert-butyl group -5- methyl-benzyls)-N- rings The fluoro- 1- methyl isophthalic acids H- pyrazole-4-carboxamides of propyl group -3- (difluoromethyl) -5-, (15.171) N- [5- chloro- 2- (trifluoromethyl) benzyls Base] the fluoro- 1- methyl isophthalic acids H- pyrazole-4-carboxamides of-N- cyclopropyl -3- (difluoromethyl) -5-, (15.172) N- cyclopropyl -3- (two Methyl fluoride) the fluoro- 1- methyl-N- of -5- [5- methyl -2- (trifluoromethyl) benzyl] -1H- pyrazole-4-carboxamides, (15.173) N- [2- chloro- 6- (trifluoromethyl) benzyl] fluoro- 1- methyl isophthalic acids H- pyrazole-4-carboxamides of-N- cyclopropyl -3- (difluoromethyl) -5-, (15.174) N- [the chloro- 2- of 3- fluoro- 6- (trifluoromethyl) benzyl] the fluoro- 1- methyl isophthalic acids H- of-N- cyclopropyl -3- (difluoromethyl) -5- Pyrazole-4-carboxamide, (15.175) N- cyclopropyl -3- (difluoromethyl)-N- (2- ethyl -4,5- dimethyl benzyls) fluoro- 1- of -5- Methyl isophthalic acid H- pyrazole-4-carboxamides, (15.176) N- cyclopropyl -3- (difluoromethyl) -5- fluoro- N- (2- isopropyl benzyls) -1- Methyl isophthalic acid H- pyrazoles -4- thioformamides, (15.177) 3- (difluoromethyl)-N- (the fluoro- 1,1,3- trimethyls -2,3- dihydros of 7- - 1H- indenes -4- bases) -1- methyl isophthalic acid H- pyrazole-4-carboxamides, (15.178) 3- (difluoromethyl)-N- [fluoro- 1,1,3- of (3R) -7- Trimethyl -2,3- dihydro -1H- indenes -4- bases] -1- methyl isophthalic acid H- pyrazole-4-carboxamides, (15.179) 3- (difluoromethyl)-N- [the fluoro- 1,1,3- trimethyls -2,3- dihydros -1H- indenes -4- bases of (3S) -7-] -1- methyl isophthalic acid H- pyrazole-4-carboxamides, (15.180) N'- (2,5- dimethyl -4- Phenoxyphenyls)-N- ethyl-N-methyls carbonamidine, (15.181) N'- { 4- [(chloro- 1,3- of 4,5- bis- Thiazol-2-yl) epoxide] -2,5- 3,5-dimethylphenyls-N- ethyl-N-methyls carbonamidine, (15.182) N- (chloro- 2,6- difluorobenzenes of 4- Base) -4- (the chloro- 4- fluorophenyls of 2-) -1,3- dimethyl -1H- pyrazoles -5- amine.

All blending ingredients that species (1) to (15) is referred to --- as its functional group allow if --- optionally with Appropriate alkali or sour forming salt, are particularly the form of biologically acceptable salt, such as sodium, potassium and ammonium.

On insecticide, acaricide and nematicide, following material can be used：

1) acetylcholinesterase (AChE) inhibitor, for example：Carbamates, such as alanycarb (Alanycarb), tears go out Prestige (Aldicarb), Ficam (Bendiocarb), Benfuracard micro (benfuracarb), butocarboxim (Butocarboxim), Butanone sulfone prestige (Butoxycarboxim), carbaryl (Carbaryl), carbofuran (Carbofuran), carbosulfan (Carbosulfan), ethiofencarb (Ethiofencarb), Osbac (Fenobucarb), Carzol (Formetanate), Furathiocarb (Furathiocarb), Mobucin (Isoprocarb), methiocarb (Methiocarb), methomyl (Methomyl), MTMC (Metolcarb), oxamyl (Oxamyl), Aphox (Pirimicarb), arprocarb (Propoxur), thiodicarb (Thiodicarb), thiofanox (Thiofanox), triaguron (Triazamate), Landrin (Trimethacarb), XMC and Meobal (Xylylcarb)；Or organophosphorus compounds, such as orthene (Acephate), azamethiphos (Azamethiphos), triazotion (Azinphos-ethyl), methyl azinphos-methyl (Azinphos-methyl), cadusafos (Cadusafos), chlorethoxyfos (Chlorethoxyfos), chlorfenviphos (Chlorfenvinphos), chlormephos (Chlormephos), chlopyrifos (Chlorpyrifos), chlorpyrifos-methyl (Chlorpyrifos-methyl), Resistox (Coumaphos), cynock (Cyanophos), demeton-methyl (Demeton-S-methyl), basudin (Diazinon), DDVP (Dichlorvos/DDVP), Carbicron (Dicrotophos), Rogor (Dimethoate), dimethylvinphos (Dimethylvinphos), disulfoton (Disulfoton), EPN, Ethodan (Ethion), phonamiphos (Ethoprophos), Famphur (Famphur), fenamiphos (Fenamiphos), fenifrothion (Fenitrothion), Entex (Fenthion), thiophene Azoles phosphorus (Fosthiazate), heptenophos (Heptenophos), Imicyafos, isofenphos (Isofenphos), O- (methoxyl groups Amino thiophosphoryl base) salicylate (O- (methoxyaminothio-phosphoryl) salicylate), karphoses (Isoxathion), malathion (Malathion), Afos (Mecarbam), acephatemet (Methamidophos), kill and flutter Phosphorus (Methidathion), Menite (Mevinphos), Azodrin (Monocrotophos), 2-dichloroethylk dimethyl phosphate (Naled), oxidation pleasure Really (Omethoate), oxydemeton_methyl (Oxydemeton-methyl), parathion (Parathion), parathion-methyl (Parathion methyl), phenthoate dimephenthoate cidial (Phenthoate), thimet (Phorate), Phosalone (Phosalone), Asia Amine sulphur phosphorus (Phosmet), phosphamidon (Phosphamidon), phoxim (Phoxim), pirimiphos-methyl (Pirimiphos- Methyl), Profenofos (Profenofos), propetamphos (Propetamphos), Toyodan (Prothiofos), pyraclofos (Pyraclofos), pyridaphethione (Pyridaphenthion), quinalphos (Quinalphos), sulfotep (Sulfotep), fourth Yl pyrimidines phosphorus (Tebupirimfos), Swebate (Temephos), terbufos (Terbufos), Ravap (Tetrachlorvinphos), thiometon (Thiometon), Hostathion (Triazophos), metrifonate And vamidothion (Vamidothion) (Triclorfon).

2) GABA gates chloride channel antagonists, for example：Cyclopentadiene organochlorine class, such as Niran (Chlordane) and 5a,6,9,9a-hexahydro-6,9-methano-2,4 (Endosulfan)；Or phenyl pyrazoles (fiproles), such as (16.1) ethiprole (Ethiprole) and (16.2) fluorine worm Nitrile (Fipronil).

3) sodium channel modulators/voltage gated sodium channel blocking agent, for example：Pyrethroid, such as acrinathrin (Acrinathrin), allethrin (Allethrin), d- cis-transes allethrin, the trans allethrins of d-, Biphenthrin (Bifenthrin), EXTHIN (Bioallethrin), EXTHIN-S- cyclopenta isomers, biological benzyl furan Chrysanthemum ester (Bioresmethrin), cycloprothrin (Cycloprothrin), cyfloxylate (Cyfluthrin), β-cyfluthrin chrysanthemum Ester, lambda-cyhalothrin (Cyhalothrin), λ-lambda-cyhalothrin, gamma-cyhalothrin, cypermethrin (cypermethrin), α-cypermethrin, β-cypermethrin, θ-cypermethrin, ζ-cypermethrin, cyphenothrin (Cyphenothrin) [(1R)-anti- Formula isomers], decis (Deltamethrin), empenthrin (Empenthrin) [(EZ)-(1R) isomers), it is high Fenvalerate (Esfenvalerate), ethofenprox (Etofenprox), Fenpropathrin (Fenpropathrin), fenvalerate (Fenvalerate), flucythrinate (Flucythrinate), flumethrin (Flumethrin), τ-taufluvalinate (tau-Fluvalinate), halfenprox (Halfenprox), miaow alkynes chrysanthemum ester (Imiprothrin), kadethrin (Kadethrin), permethrin (Permethrin), phenothrin (Phenothrin) [(1R)-transisomer), dextrorotation alkynes Third chrysanthemum ester (Prallethrin), pyrethrin (Pyrethrine (pyrethrum)), resmethrin (Resmethrin), fluorine silicon Chrysanthemum ester (Silafluofen), Tefluthrin (Tefluthrin), tetramethrin (Tetramethrin), tetramethrin [(1R) isomery Body], tralomethrin (Tralomethrin) and transfluthrin (Transfluthrin), or DDT or methoxychlor (Methoxychlor)。

4) nAChR (nAChR) activator, for example：Anabasine, such as (17.1) Acetamiprid (Acetamiprid), (17.2) clothianidin (Clothianidin), (17.3) MTI-446 (Dinotefuran), (17.4) pyrrole worm Quinoline (Imidacloprid), (17.5) Nitenpyram (Nitenpyram), (17.6) thiacloprid (Thiacloprid) and (17.7) Diacloden (Thiamethoxam), or (17.8) nicotine (Nicotine) or (17.9) sulfoxaflor (Sulfoxaflor).

5) nAChR (nAChR) allosteric activator, for example：Pleocidin class (spinosyns), such as (18.1) ethyl pleocidin (Spinetoram) and (18.2) multiple killing teichomycin (Spinosad).

6) chloride channel activators, for example：Avermectins/mibemycin class, such as AVM (Abamectin), emamectin-benzoate (Emamectin benzoate), thunder cuticulin (Lepimectin) and Close spit of fland of going out (Milbemectin).

7) juvenile hormone mimics agent, for example：Juvenoid class, such as hydroprene (Hydroprene), alkene worm alkynes Ester (Kinoprene) and methoprene (Methoprene), or fenoxycarb (Fenoxycarb) or Nylar (Pyriproxyfen)。

8) non-specific (many sites) inhibitor is mixed, for example：Alkyl halide, such as methyl bromide and other alkyl halides；Or chlorine Change bitter (Chloropicrin) or vikane (Sulfuryl fluoride) or borax (Borax) or tartar emetic (Tartar emetic)。

9) selective Homoptera takes food blocking agent (feeding blocker), for example：Pymetrozine (Pymetrozine) and Flonicamid (Flonicamid).

10) mite growth inhibitor, for example：Clofentezine (Clofentezine), Hexythiazox (Hexythiazox) and fluorine mite Piperazine (Diflovidazin) or etoxazole (Etoxazole).

11) insect goldbeater's skin microorganism agent interfering, for example：Bacillus thuringiensis subsp israelensis (Bacillus Thuringiensis subspecies israelensis), Bacillus sphaericus (Bacillus sphaericus), Su Yun Golden bacillus Aizawa subspecies (Bacillus thuringiensis subspecies aizawai), bacillus thuringiensis Ku Er Starks subspecies (Bacillus thuringiensis subspecies kurstaki), bacillus thuringiensis intend step Row first subspecies (Bacillus thuringiensis subspecies tenebrionis), and BT crop albumen： Cry1Ab、Cry1Ac、Cry1Fa、Cry2Ab、mCry3A、Cry3Ab、Cry3Bb、Cry34/35Ab1。

12) mitochondrial ATP synthase inhibitor, for example：Diafenthiuron (Diafenthiuron) or organotin acaricide, such as three Azoles tin (Azocyclotin), plictran (Cyhexatin) and fenbutatin oxide (Fenbutatin oxide), or propargite Or tetradiphon (Tetradifon) (Propargite).

13) by interrupting the oxidative phosphorylation uncoupler of proton gradient, for example：Capillary (Chlorfenapyr), DNOC and sulfluramid (Sulfluramid).

14) nAChR (nAChR) channel blocker, for example：Bensultap (Bensultap), Padan's hydrochloric acid Salt (Cartap hydrochloride), thiocyclam (Thiocyclam) and dimehypo (Thiosultap-sodium).

15) benzoylurea derivertives, 0 type, for example：Bistrifluron (bistrifluron), chlorfluazuron (chlofluazuron), diflubenzuron (diflubenzuron), flucycloxuron (flucycloxuron), flufenoxuron (flufenoxuron), HEXAFLUMURON (hexaflumuron), lufenuron (lufenuron), novaluron (novaluron), polyfluoro Urea (noviflumuron), fluorobenzene urea (teflubenzuron) and triflumuron (triflumuron).

16) benzoylurea derivertives, 1 type, for example：Buprofezin (Buprofezin).

17) cast off a skin agent interfering, for example：Cyromazine (Cyromazine).

18) ecdysone receptor activator, for example：Ring tebufenozide (Chromafenozide), chlorine tebufenozide (Halofenozide), methoxyfenozide (Methoxyfenozide) and tebufenozide (Tebufenozide).

19) octopamine receptor activator, for example：Amitraz (Amitraz).

20) Mitochondria complex III electron transfer inhibitors, for example：Hydramethylnon Bait (Hydramethylnone) or acequinocyl Or fluacrypyrim (Fluacrypyrim) (Acequinocyl).

21) Mitochondria complex I electron transfer inhibitors, for example：METI acaricides, such as fenazaquin (Fenazaquin), fenpyroximate (Fenpyroximate), pyrimidifen (Pyrimidifen), pyridaben (Pyridaben), pyrrole mite Amine (Tebufenpyrad) and Tolfenpyrad (Tolfenpyrad) or rotenone (Rotenone (Derris)).

22) voltage gated sodium channel blocking agent, for example：Indoxacarb (Indoxacarb) or metaflumizone (Metaflumizone)。

23) acetyl CoA carboxylase inhibitor, for example：Tetronic acid (tetronic acid) and tetramic acid The derivative of (tetramic acid), such as Envidor (spirodiclofen), Spiromesifen (spiromesifen) and spiral shell worm Ethyl ester (Spirotetramat).

24) Mitochondria complex IV electron transfer inhibitors, for example：Phosphine, such as aluminum phosphate, calcium phosphide, phosphine and zinc phosphide； Or cyanide.

25) Mitochondria complex II electron transfer inhibitors, for example：Nitrile pyrrole mite ester (Cyenopyrafen) and cyflumetofen (Cyflumetofen)。

28) ryanodine receptor conditioning agent, for example：Diamide, such as (19.1) Rynaxypyr (Chlorantraniliprole), (19.2) bromine cyanogen insect amide (Cyantraniliprole) and (19.3) fipronil bisamide (Flubendiamide)。

Other binding modes are unknown or undetermined active component, for example：Afidopyropen, nimbin (Azadirachtin), Benclothiaz, Citrazon (Benzoximate), Bifenazate (Bifenazate), fenisobromolate (Bromopropylate), quinomethionate, ice crystal (Cryolite), dicofol (Dicofol), flufenzine (Diflovidazin), fluorine thiophene worm sulfone (Fluensulfone), Flometoquin, phonetic worm amine (Flufenerim), fluorine bacterium mite ester (Flufenoxystrobin), butene-fipronil (Flufiprole), fluopyram (Fluopyram), fluorine pyrrole furanone (Flupyradifurone), furan tebufenozide (Fufenozide), Heptafluthrin, imidaclothiz (Imidaclothiz), Iprodione (Iprodione), fluorine chlorine ether chrysanthemum ester (Meperfluthrin), paichongding (Paichongding), Pyflubumide, Pyrifluquinazon, pyriminostrobin (Pyriminostrobin), etrafluorine ethofenprox (Tetramethylfluthrin) and iodine first Alkane；And the product based on bacillus firmus (Bacillus firmus) in addition (includes but is not limited to bacterial strain CNCM I- One of 1582, such as VOTiVO TM, BioNem) or following known reactive compound：The bromo- N- of 3- { chloro- the 6- [(1- of the bromo- 4- of 2- Cyclopropylethyl) carbamoyl] phenyl } -1- (3- chloropyridine -2- bases) -1H- pyrazoles -5- formamides (are known in WO2005/ 077934) with 1- { the fluoro- 4- methyl -5- of 2- [(2,2,2- trifluoroethyls) sulfinyl] phenyl } -3- (trifluoromethyl) -1H-1, 2,4- triazole -5- amine (being known in WO2006/043635), { 1'- [(2E) -3- (4- chlorphenyls) propyl- 2- alkene -1- bases] -5- fluorine spiral shells [indoles -3,4'- piperidines] -1 (2H)-yl } (2- chloropyridine -4- bases) ketone (being known in WO2003/106457), the chloro- N- [2- of 2- { 1- [(2E) -3- (4- chlorphenyls) propyl- 2- alkene -1- bases] piperidin-4-yl } -4- (trifluoromethyl) phenyl] Pyrazinamide (is known in WO2006/003494), 3- (2,5- 3,5-dimethylphenyls) -4- hydroxyl -8- methoxyl group -1,8- diaza spiros [4.5] decyl- 3- alkene -2- Ketone (being known in WO2009/049851), 3- (2,5- 3,5-dimethylphenyls) -8- methoxyl group -2- oxo -1,8- diaza spiros [4.5] Decyl- 3- alkene -4- base ethyl carbonate esters (being known in WO2009/049851), 4- (butyl- 2- alkynes -1- bases epoxide) -6- (3,5- diformazans Phenylpiperidines -1- bases) -5-FU (being known in WO2004/099160), 4- (butyl- 2- alkynes -1- bases epoxide) -6- (3- chlorphenyls) Pyrimidine (being known in WO2003/076415), PF1364 (CAS Registry Number 1204776-60-2), 4- [5- (3,5- dichlorophenyls)- 5- (trifluoromethyl) -4,5- dihydro -1,2- oxazole -3- bases] -2- methyl-N- { 2- oxos -2- [(2,2,2- trifluoroethyls) ammonia Base] ethyl benzamide (being known in WO2005/085216), 4- { 5- [3- chloro- 5- (trifluoromethyl) phenyl] -5- (fluoroforms Base) -4,5- dihydro -1,2- oxazole -3- bases }-N- { 2- oxos -2- [(2,2,2- trifluoroethyls) amino] ethyl } -1- naphthalene formyls Amine (being known in WO2009/002809), 2- [2- ({ [the bromo- 1- of 3- (3- chloropyridine -2- bases) -1H- pyrazoles -5- bases] carbonyl } ammonia Base) the chloro- 3- methyl benzoyls of -5-] -2- methyl methyl carbazate (being known in WO2005/085216), [({ [3- is bromo- by 2- by 2- 1- (3- chloropyridine -2- bases) -1H- pyrazoles -5- bases] carbonyl } amino) -5- cyano group -3- methyl benzoyls] -2- ethyl hydrazine formic acid Methyl esters (being known in WO2005/085216), 2- [2- ({ [the bromo- 1- of 3- (3- chloropyridine -2- bases) -1H- pyrazoles -5- bases] carbonyl } ammonia Base) -5- cyano group -3- methyl benzoyls] -2- methyl methyl carbazate (being known in WO2005/085216), [3,5- bis- is bromo- by 2- 2- ({ [the bromo- 1- of 3- (3- chloropyridine -2- bases) -1H- pyrazoles -5- bases] carbonyl } amino) benzoyl] -2- ethyl methyl carbazates (being known in WO2005/085216), 1- (3- chloropyridine -2- bases)-N- [4- cyano group -2- methyl -6- (methylcarbamoyl) benzene Base] -3- { [5- (trifluoromethyl) -2H- tetrazolium -2- bases] methyl } -1H- pyrazoles -5- formamides (are known in WO2010/ 069502), N- [2- (5- amino -1,3,4- thiadiazoles -2- bases) the chloro- 6- aminomethyl phenyls of -4-] the bromo- 1- of -3- (3- chloropyridines -2- Base) -1H- pyrazoles -5- formamides (being known in CN102057925), the chloro- N- of 3- (2- cyano group propyl- 2- yls)-N- [4- (1,1,1,2, The fluorine propyl- 2- yls of 3,3,3- seven) -2- aminomethyl phenyls] phthalamide (being known in WO2012/034472), [(2- is chloro- by the chloro- N- of 8- 5- methoxyphenyls) sulfonyl] -6- (trifluoromethyl) imidazo [1,2-a] pyridine-2-carboxamide (is known in WO2010/ 129500), the chloro- N- of 8- [(2- chloro-5-methoxyls phenyl) sulfonyl] -6- (trifluoromethyl) imidazo [1,2-a] pyridine -2- first Acid amides (being known in WO2009/080250), N- [(2E) -1- [(6- chloropyridine -3- bases) methyl] pyridine -2 (1H)-subunit] -2, 2,2- trifluoroacetamides (being known in WO2012/029672), 1- [(the chloro- 1,3- thiazoles -5- bases of 2-) methyl] -4- oxo -3- benzene Base -4H- pyrido [1,2-a] pyrimidine -1--2- alcohol/phenates (being known in WO2009/099929), 1- [(6- chloropyridines -3- Base) methyl] -4- oxo -3- phenyl -4H- pyrido [1,2-a] pyrimidine -1--2- alcohol/phenates (is known in WO2009/ 099929), (5S, 8R) -1- [(6- chloropyridine -3- bases) methyl] -9- nitro -2,3,5,6,7,8- hexahydro -1H-5,8- epoxy radicals Imidazo [1,2-a] azepine (being known in WO2010/069266), (2E) -1- [(6- chloropyridine -3- bases) methyl]-N'- Nitro -2- pentylidene hydrazine carbonamidines (being known in WO2010/060231), 4- (3- the chloro- 4- of 2,6- bis- [(3,3- dichloro propyl- 2- alkene - 1- yls) epoxide] phenoxy group propoxyl group) -2- methoxyl groups -6- (trifluoromethyl) pyrimidine (being known in CN101337940), N- [2- The chloro- 6- aminomethyl phenyls of (t-Butylcarbamoyl) -4-] -1- (3- chloropyridine -2- bases) -3- (fluorine methoxyl group) -1H- pyrazoles -5- Formamide (is known in WO2008/134969).

Although a kind of agricultural chemicals or a variety of agricultural chemicals can be independently selected from above-mentioned substances, and can also appoint What possible mode is combined, but preferably at least a kind of agricultural chemicals are selected from：Isotianil, fluorine azoles ring bacterium amine, fluorine azoles bacterium aniline, Azoles fungicide class (particularly Tebuconazole, kind bacterium azoles, propiconazole or Difenoconazole), strobilurin classes (are particularly oxime bacterium Ester, Fluoxastrobin or ZEN 90160), pyrrole metsulfovax, metalaxyl, fludioxonil, tiadinil, ethiprole, fipronil bisamide, chlorine worm benzene Formamide, bromine cyanogen insect amide, imidacloprid, thiacloprid, Diacloden, clothianidin, multiple killing teichomycin, ethiprole or its mixture, preferably For isotianil and trifloxystrobin, isotianil and fluorine azoles bacterium aniline, fluorine azoles bacterium aniline and trifloxystrobin or isotianil and pyridine worm The combination of amidine.Particularly preferably isotianil.These agricultural chemicals particularly preferred for the present invention seed rice coating, because of it Suitable for the specific disease of rice and insect, and because the copolymer of the present invention effectively prevent these materials by the kind from coating Washed off on son.

The seed pelleting can also include at least one colouring agent, surfactant, organic solvent and/or other polymerizations Thing or copolymer.Addition colouring agent such as red, green, blue etc. is had the advantage that everyone easily has found that the seed rice is place Managed, thus danger of the rice unintentionally for food purpose will be coated and be greatly lowered.In addition, colouring agent can be displayed in immersion And be coated and still retain on seed in cultivating process.The colouring agent for example not only can be selected but also can passed through by its color It oozes out property and selected from coating, makes it similar to the agricultural chemicals used in coating.So, can using people Coating is actually seen in fact not to be washed off.In this case, colouring agent can be used as oozing out the sxemiquantitative benchmark of property, example Such as by the way that the color table of relation between the seed color before and after immersion and instruction color and agricultural chemicals content is compared. For the purpose of the color intensity before and after immersion, spectrographic technique can be also used.In addition, colouring agent may further indicate that the quality of coating, Display is on the coating uniformity between whole seed or all seeds.

Used colouring agent can be perceived color, or be alternatively UV- dyestuffs.Inorganic colourant is such as used, then It can be simultaneously as the source of trace element.

The coating can have any possible structure or sequence.According to a preferred embodiment, by the copolymerization Thing and agricultural chemicals are mixed before seed is applied to, and especially, then by the seed rice of coating with other agricultural chemicals, It is preferred that using pesticide treatments.The agricultural chemicals mixed with the copolymer are advantageously fungicide.

Or, the copolymer and agricultural chemicals can be applied to seed in an orderly manner, and it is preferred that the seed is used first Then at least one agricultural chemicals are coated with the copolymer.

The rate of application of the copolymer can change in wide scope.The rate of application is such as 0.001 weight % to 2.5 weights Measure %, particularly 0.01 weight % to 1.25 weight %, preferably 0.025 weight % is to 1 weight %, relative to undressed kind The weight meter of son.

The rate of application of the agricultural chemicals depends primarily on dose requirements, and can be used by technical staff.Only as act Example, the rate of application of agricultural chemicals is 0.001 weight % to 5 weight %, is particularly 0.01 weight % to 2.5 weight %, preferably 0.05 weight % is to 1 weight %, based on the weight of undressed seed.Provide the non-limiting of specific fungicide Example, the rate of application of isotianil is chosen as 0.05 weight % to 2 weight %, is particularly 0.1 weight % to 1 weight %, and oxime The rate of application of bacterium ester is then chosen as 0.01 weight % to 1 weight %, particularly 0.05 weight % to 0.5 weight %, each relative In the weight meter of undressed seed.

The agricultural chemicals can be used with any available form or preparation, such as solid such as (wettable) powder End, water soluble preparation, liquid preparation, the liquid that can be applied, waterborne suspension, dispersion or emulsion, microcapsule formulation, are only provided Several examples.The preparation can be by known method, for example by by agricultural chemicals and solvent (developers) (i.e. liquid Body or solid diluent or carrier), and also mixed in some cases with surfactant (i.e. emulsifying agent and/or dispersant) and Obtain.In the case where using water as solvent, for example, organic solvent can be used to be used as cosolvent.

In the present invention, from the viewpoint of machinability, the preferred waterborne suspension of agricultural chemicals.As aqueous outstanding Supernatant liquid agent, from the viewpoint of effect durability, also includes water, surfactant, liquid particularly preferably in addition to agricultural chemicals Diluent (organic solvent) and fluoropolymer resin --- especially acrylic resin (including alkyl acrylate and/or methyl-prop The (co) polymerization resin of olefin(e) acid Arrcostab) aqueous suspension composition.

As needed, defoamer, preservative, thickener, dispersant, antifreezing agent etc. can be added to the agricultural chemicals Waterborne suspension in.In aqueous suspension composition, the preferred contents of agricultural chemicals is 1 weight % to 50 weight %, Particularly 5 weight % to 40 weight %.The preferred content of surfactant is 0.01 weight % to 10 weight %, particularly 0.1 Weight % to 5 weight %.The preferred content of diluent is 1 weight % to 50 weight %, particularly 5 weight % to 30 weight %. The preferred content of acrylic resin is 0.1 weight % to 20 weight %, particularly 1 weight % to 10 weight %.For other Adding ingredient such as defoamer, preservative and thickener, its preferred total content be 0 weight % to 10 weight %, particularly 0.1 Weight % to 5 weight %.It is preferred that using particulate polymeric resin as the fluoropolymer resin in aqueous suspension composition, and Those of fine crushing particularly preferably by grinding etc..

As liquid diluent or the example of carrier, aromatic hydrocarbon (such as dimethylbenzene, toluene, alkylnaphthalene there can be mentioned Deng), chlorinating aromatic compounds or chlorinated aliphatic hydrocarbons (such as chlorobenzene, dichloroethanes, dichloromethane), aliphatic hydrocarbon (such as ring Hexane etc., paraffin (such as mineral oil fractions)), alcohol (such as C_2-10Alcohol such as butanol, ethylene glycol, glycol such as propane diols etc., with And its ether, ester etc.), ketone (such as acetone, methyl ethyl ketone, methyl iso-butyl ketone (MIBK), cyclohexanone), intensive polar solvent (such as two NMF, dimethyl sulfoxide etc.), water etc..

As solid diluent or the example of carrier, there can be mentioned crushing natural crystal (for example kaolin, clay, Talcum, chalk, quartz, attapulgite, montmorillonite, diatomite etc.), synthesis ore (such as bentonite, silicic acid, the oxidation of crushing Aluminium, silicate, quartz sand etc.) etc..As the example of the solid carrier of granular preparation, the rock crushed and be classified there can be mentioned (such as calcite, marble, float stone, sepiolite, dolomite), inorganic and organic dust synthesis particle, organic substance (example Such as sawdust, coconut husk, corncob, tobacco stem stalk) fine particle etc..

As the example of surfactant, nonionic and anion surfactant (such as polyoxyethylene there can be mentioned Fatty acid ester, polyoxyethylene fatty acid alcohol ether (such as alkylaryl polyglycol ether, alkylsulfonate, alkyl sulfate, aryl sulfonic acid Salt), triphenyl vinyl phenol and its ethoxylate), albumin hydrolysate etc..

It is used as the example of dispersant, it may include lignin-sulfite waste liquid, methylcellulose etc..

Adhesive also may be added to that in preparation (powder formulation, granular preparation, emulsion agent), and be used as described adhesive Example, there can be mentioned carboxymethyl cellulose, natural and synthesis polymer (such as gum arabic, polyvinyl alcohol, poly- acetic acid Vinyl acetate etc.).

Colouring agent can also be used in the formulation, and as the example of the colouring agent, there can be mentioned inorganic pigment (example Such as iron oxide, titanium oxide, Prussian blue), and organic dyestuff such as alizarin dyes, azo dyes and metallized phthalocyanine dye, and The metal salt of micro- such as iron, manganese, boron, copper, cobalt, molybdenum, zinc.

It is not particularly limited for the coating of the present invention is provided to the method for seed rice.Coated composition can be liquid shape Formula, but it is also possible to which agricultural chemicals are solid form and copolymer is liquid form.In the case, any powder bag can be passed through Clothing method takes agricultural chemicals on the surface of the seed to, then carries out any liquid coatings method of copolymer.The coating can Apply, but if to apply other coatings, can also be applied in two or more steps in one step.

As the method for powder coating, for example, there are as below methods, wherein seed rice and agricultural chemicals are placed in into rotating cylinder In, and seed rice agricultural chemicals is uniformly coated by rotating the roller.It is used as sprinkling agricultural chemicals, copolymer or two The method of the mixture of person, for example, there are as below methods：(1) a kind of method, wherein by using suitable nozzle by agrochemicals The mixture of product, copolymer or both is directly sprayed on the seed rice fallen from hopper etc.；(2) a kind of method, wherein will vibration Guide plate is connected to nursery box from hopper, and when seed rice onboard bounce by when, using suitable nozzle agricultural chemicals, The mixture sprinkling seed rice of copolymer or both；And a kind of (3) method, wherein the roller that seed rice is passed through be arranged on hopper with Between above nursery box, and the mixture of agricultural chemicals, copolymer or both is sprayed onto on the seed rice by the roller.

As the method for the small-scale mixture that agricultural chemicals, copolymer or both are sprayed to seed rice, it can also use Following method, wherein seed rice is placed in whirler (such as mortar mixer), and with appropriate sprinkler by the agriculture of predetermined close Uniformly it is sprayed to the mixture of chemicals, copolymer or both on seed rice.Also, it can also adopt with the following method, wherein by rice It is the seed rice two into the polybag or appropriate containers of three times kind to be placed in volume, and in addition agricultural chemicals, copolymer or two Closed and (for polybag, closed sack entrance after being full of air in bag, so that whole bag after the mixture of person Son inflation), shake and stir so that the mixture of agricultural chemicals, copolymer or both expands in the inside of whole container or bag Dissipate.

In the case where being sprayed to a large amount of seed rice, it can pacify at the middle part for leading to the conveying device of nursery box seeder Nozzle is filled to spray the mixture of agricultural chemicals, copolymer or both.Then it can be blended step and optional drying walked Suddenly.

Another embodiment of the invention is seed rice inorganic agent, it is characterised in that the inorganic agent is included

Vinyl-vinyl acetate copolymer, and

At least one agricultural chemicals.

The seed rice inorganic agent can have any improvement as described above on the inventive method bar none.

Yet another embodiment of the present invention is the seed rice being coated, and the seed rice of the coating is at least partially with rice of the invention Inorganic agent is planted to be coated.

As described above, the coating of the present invention protects seed from disease and insect, and there is no significant impact to germination percentage.Cause This, can still maintain to apply typical seed rice preparation method (including soak and cultivate in water before sowing) known to people.Preferably, originally The seed rice is being soaked and then is cultivating the seed rice of immersion 144 hours at 7 DEG C by the seed rice of the coating of invention in 25 DEG C of water After (6 days), compared with the undressed seed rice of same breed and age, show average germination percentage reduction by 0 to 10%, preferably 0 to 5%.The immersion of seed is for example carried out by the way that 30 seeds are spread out and put in spraying 50mL water on cotton paper and on the paper.So Paper roll is risen afterwards and is placed in the tank of closing, and exposed to the dark place (such as in refrigerator) of said temperature and damp condition.Germination Experiment is carried out under experimental condition explained above, and assesses by calculating at least 30 seeds (random selection) to make.Should Test using at least three samples for soaking and cultivating in different vessels to carry out, and calculate average germination percentage.

In addition, the seed rice of the coating can be in the feelings without significantly reduced germination percentage and/or agrochemical activity loss The several months is stored under condition.

The seed rice of the coating of the present invention allows to be immersed in water without causing agricultural chemicals by washing off or oozing out A large amount of losses.In a preferred embodiment of the invention, the seed rice of the coating by the seed rice in 25 DEG C of water nothing During stirring immersion 24 hours, it is 5 weight % or less, particularly 3 weight % to show the release rate of agricultural chemicals Or it is less, compared to the gross weight meter of the agricultural chemicals in coating.The agricultural chemicals are in particular selected from fungicide.

Another embodiment of the invention be for protect before planting the newborn rice shoot resistance fungal disease of rice plant and/ Or the method for insect, this method comprises the following steps：

A. preferably at a temperature of 10 to 40 DEG C, more preferably 20 to 30 DEG C, the seed rice of the coating of the present invention is soaked in water Bubble, especially soaks at least 12 hours, and

B. if desired, the seed rice of immersion is cultivated at least 36 hours, especially cultivate at least 72 hours,

At least one other agricultural chemicals are optionally wherein applied to the rice in immersion and/or cultivating process Kind, and wherein described other agricultural chemicals in particular insecticide, preferably Diacloden, imidacloprid, clothianidin or they Mixture.With it, protective value can be adjusted to corresponding to actual needs, such as when the harm of harmful insect is serious. The seed rice for example can be in the incubation step in nursery box (such as size is 60cm × 30cm × 3cm) after immersion or optionally Sowed afterwards.However, seed rice is directly sowed after steeping in field for cultivate or sow in the seedling system of field with For subsequently transplanting also within the scope of the invention.

Immersion process on seed rice preferably is used to protect newborn rice shoot in principle without any limitation above-mentioned Seed rice is set to absorb enough water in method, while there is the accumulated temperature in 60 to 140 DEG C of days (for example, 7 to 10 at 13 to 14 DEG C My god).Cultivate can for example after steeping in carried out at 20 to 40 DEG C, at preferably 25 to 35 DEG C at least 24 hours, preferably at least 72 Hour or even 132 hours.

For seed rice is seeded in nursery box and made after mulching soil method that rice emerges, by shoot transplanting equipment to rice field with And the method for cultivation rice is not particularly limited after transplanting, and can be using known method.For example, covering seed with soil Afterwards, each nursery box is placed in nursery cabinet and makes germination, nursery box is then moved into seedling rearing room and further cultivated. Only need using cultivator etc. come by the shoot transplanting equipment of cultivation in rice field.It is same that the breeding method to rice field is transplanted for rice Sample is not limited, and can cultivate rice according to conventional methods.

Compared with the seed being directly coated with corresponding agricultural chemicals, when coating of the invention allows generally for persistently longer Between protection, while needing lesser amount of agricultural chemicals.For example, in the side for being used to protect the newborn rice shoot of rice plant of the present invention In method, when at 50 days or more days after the seed that will be soaked and cultivate is transplanted, particularly 60 days or more days, still it can be observed Protection to disease and/or insect.Realize that the targeted typical disease of protection is caused by filamentous fungi and/or microorganism.It is described Disease is withered in particular selected from rice blast (being caused by Rice Blast Fungus (Pyricularia oryzae)), paddy rice brown spot or Rice Panicle Sick (being caused by palace portion cochliobolus (Cochliobolus miyabeanus)), rice sheath blight disease are (by Rhizoctonia solani Kuhn (Rhizoctonia solani) causes), the bacterial blight of rice is (by rice bacterial leaf spot pathogenic bacteria (Xanthomonas oryzae Pv.oryzae) cause), the bacillary Maize Ear Rot of rice (being caused by the bacillary glume blight bacterium of rice (Burkholderia glumae)) or Combinations thereof.

In the another aspect of the newborn rice shoot method of the protection of the present invention, the insect is animal pest, its in particular selected from Rice water weevil (Lissorhoptrus oryzophilus), rice leaf beetles (Oulema oryzae Kuwayama), Delphacidae (Delphacidae), rice green leafhopper (Nephotettix cincticeps), paddy stem maggot (Hydrellia griseola (rice leaf miner)), rice hesperiidae (Parnara guttata (rice skipper)), rice green caterpillar (Narang Aaenescens Moore), rice leaf roller (Cnaphalocrocis medinalis), striped rice borer (Chilo Suppressalis), rice thripses (Stenchaetothrips biformis (rice thrips)) or combinations thereof.

The present invention will be further illustrated based on following examples.

The material used：

Agrochemical formulation：

As agricultural chemicals, the water base preparation containing isotianil (200g/L) and trifloxystrobin (80g/L) is used.Should The total water content of preparation is about 60 weight %, and red pigment and other additives such as defoamer also containing 2.5 weight %, The mixture of thickener etc..Hereinafter, it is further referred to as " agrochemical formulation ".

Copolymer：

As copolymer, non-plasticizing aqueous copolymer dispersion is used：

Altox^TM1656 products from Croda Crop Care, the non-plasticizing aqueous copolymer based on following monomer Dispersion

Monomer A

CAS 108-05-4, vinyl acetate

C₄H₆O₂, AcO-CH=CH₂

35-50%

Monomer B

CAS 103-11-7,2-EHA

C₁₁H₂₀O₂

25-55% flexibility (methyl) acrylic monomers

Monomer C

CAS 74-85-1, ethene

CH₂=CH₂

5-25%

Monomer A+B+C percentage adds up to 100%.

In addition, although the copolymer does not contain acrylic acid in itself, but product contains acrylic acid, because it can be used as the one of synthesis Part is added.

Monomer D

CAS 79-10-7, acrylic acid

C₃H₄O₂

Exist with (i.e. in copolymer dispersion) 0-5% of all over products.

Acrylic acid can be firstly added to start polymerisation.The acrylic acid does not form the part of copolymer, but deposits really Stay in product, and thus exist in the form of monomer and acrylate copolymer --- different from copolymer ---.

The solids content of the copolymer dispersion is about 59 weight % to 61 weight % (DIN EN ISO 3251；30 points Clock；130℃).

The Tg of produced polymer is -30 DEG C.The dispersion not plasticizer-containing or alkylphenol ethoxylate.

Brookfield viscosity (DIN EN ISO 2555；RVT；Rotor number 4；20rpm, 25 DEG C)-lower limit -2, 000mPas, the upper limit-mPas 10,000mPas.

PH value (DIN ISO 976；With water 1:1)-lower limit -4.5, the upper limit -6.5.

The granularity of dispersion--0.2 μm of lower limit, -2.0 μm of the upper limit, by laser-aerosol spectrum method with 2W/532nm's Nd:YVO4 laser (Millenie II) and Bialkali Photocathode Type 4517 (Fa.Burle) are with 40 ° Angle (being calculated in the range of 80nm to 550nm) is measured on the particle of spray drying.

- 0 DEG C of MFT (MFFT) (DIN ISO 2115)

Experiment：

The preparation of seed treatment formulations：

Prepare following seed treatment formulations of the invention and contrast：

* the preparation that measure 9mL is provided corresponds to quality 10.05g.

Table 1：Seed treatment formulations

In order to obtain seed treatment formulations, in the tank that polymeric dispersions are added to 60mL, and agricultural chemicals system is added Agent.Mixture is carried out under 9500rpm by IKA Ultra Turrax to high shear mixing 2 minutes, using forward thereafter It is dynamic 30 minutes.

Seed treatment

In order to prepare the seed rice of coating, in conical flask, 1.00g seed treatment formulations are added to 50.0g seed rice, and Rotate 30 minutes at room temperature, to make coating uniformly be sprawled on the surface of the seed.Rate of application is equivalent to the dry seed rice of 20g/kg, base In liquid seed treatment formulations meter.Herein, " dry " means that seed has the typical residual water content for seed rice, Such as 14 weight % or less.Because the color of the seed treatment formulations is very red, therefore it can observe by the naked eye uniform It is coated.In addition, Flasks surface almost redfree, this shows that the seed treatment formulations more strongly stick to seed compared with glass On.Thereafter, seed is spread out and put on flat board, and be dried at room temperature for one day.

HPLC determines release of the agricultural chemicals in rinse water

In order to determine adhesiveness of the agricultural chemicals for seed rice, the seed for being coated and drying is immersed in water and cultivated and is made In agent (it is the method before typical sowing).During this process, the sample of soaking water is collected in set time point, and pass through HPLC is analyzed its isotianil and trifloxystrobin content.

The concentration that isotianil and trifloxystrobin correspond to theoretical maximum burst size (100 weight %) is calculated as 720 μ g/ respectively ML and 288 μ g/mL, and the release rate of the material is relevant with this tittle.

After 48 hours, the embodiment of the present invention 1 and 2 and comparative example 3 comprising copolymer dispersion show following Isotianil and trifloxystrobin release

Embodiment 1：The weight % of isotianil 0.2；The weight % of trifloxystrobin 0.8

Embodiment 2：The weight % of isotianil 0.6；The weight % of trifloxystrobin 1.3

Embodiment 3：The weight % of isotianil 6.5；The weight % of trifloxystrobin 11.8

Relatively showing between embodiment 1 and 2, reduces by 50 weight % so that isotianil 48 hours by copolymer concentration Release afterwards increases to 0.6% from 0.3% and release of the trifloxystrobin after 48 hours increases to 1.3% from 1.0%, and it corresponds to total Activity component concentration increase to 8.0 μ g/mL from 5.3 μ g/mL.

Germination test

Germination test is also carried out.The seed rice of the amount of 30 to 40 is spread out and put on cotton paper, and 50mL is sprayed on the paper Water.Then by paper roll rise be placed in closing tank in, and exposed to 7 DEG C and about 55% relative humidity under.Cultivate progress 144 small When (6 days), and seed is grouped into the following development stage by naked eyes：" no germination ", " germinate (bud or root at edge<1cm)”、 " only root (bud 5mm) " and " solid root and bud ".

Germination % results obtained by three repeat samples test as each test object are summarized in table 3 below：

Table 3：It is present in the percentage of development stage 1-4 seed

Seed percentage of the treated seed of all batches in development stage 1-3 with undressed control group It is similar.Germination of the treated seed of all batches in the stage 4 is lower slightly compared with undressed control group (sample 1). But the experiment shows, by the way that embodiments of the invention 1 and 2 and comparative example 3 are compared, notable difference is had no.

Conclusion

Two (Examples 1 and 2) of embodiment of the present invention and comparative example (embodiment 3) display, bag of the invention Clothing (i) is for no negative effect of germinateing, and (ii) is firm and resists the property washed off with improved.The seed pelleting preparation of the present invention It is stable, and can be easily applied to the surface of the seed without leaving substantial amounts of residue on mixing machinery part.

Claims

1. a kind of method for being used to prepare the seed rice being coated, wherein seed pelleting to be applied to the table of dry seed rice at least in part Face, it is characterised in that the seed pelleting includes at least one vinyl-vinyl acetate copolymer and at least one agrochemicals Product.

2. according to the method described in claim 1, it is characterised in that the copolymer is by making at least following monomer reaction It is standby：

A. vinyl acetate,

B. (methyl) acrylic monomer of formula (I) is led to

C. ethene.

3. method according to claim 2, it is characterised in that the copolymer is prepared by least following material：

A.35 weight % to 50 weight %, particularly 38 weight % to 48 weight %, preferably 40 weight % to 45 weight % second Vinyl acetate,

B.25 weight % to 55 weight %, particularly 30 weight %'s to 50 weight %, preferably 35 weight % to 45 weight % is logical (methyl) acrylic monomer of formula (I),

C.5 weight % to 25 weight %, particularly 10 weight % to 25 weight %, preferably 15 weight % to 23 weight % second Alkene, and

D.0 weight % to 5 weight %, particularly 0.1 weight % to 4.5 weight %, preferably 0.5 weight % are to 4.0 weight %'s Acrylic acid.

4. according to the method in claim 2 or 3, it is characterised in that R has 4 to 15, particularly 5 to 10 carbon atoms, And it is preferably chosen from normal-butyl, n-pentyl, n-hexyl, cyclohexyl, different heptyl, n-nonyl, positive decyl, isohesyl, isoborneol Base, 2- ethyloctanyls, iso-octyl, 2- ethylhexyls, tetrahydrofurfuryl, ethoxyethoxyethyl, Phenoxyethyl, ring trimethyl Propane dimethoxym ethane, 3,3,5- trimethylcyclohexyls, tert-butylcyclohexyl and/or the tert-butyl group.

5. according to any method of the preceding claims, it is characterised in that the copolymer is ethylene-acrylic acid 2- Ethylhexyl-vinyl acetate copolymer.

6. according to any method of the preceding claims, it is characterised in that the glass transition temperature of the copolymer It is -60 DEG C to 20 DEG C to spend Tg, and the glass transition temperature Tg is according to DIN53 765, by dynamic DSC, uses Nitrogen is surveyed using tangential method in the 20K/min rates of heat addition and in the case that Tg is defined as into neutral temperature as inert gas Amount, and in particular -10 DEG C or lower, preferably -20 DEG C or lower of Tg.

7. according to any method of the preceding claims, it is characterised in that by the copolymer with the shape of dispersion Formula, be particularly applied to seed in the form of aqueous based dispersions, and apply be coated after the seed rice is dried.

8. method according to claim 7, it is characterised in that the Brookfield viscosity of the dispersion be 1,000 to 30,000mPas, 1 is particularly, 500 to 20,000mPas, preferably 2,000 to 10,000mPas, Brookfield glue Degree is according to DIN EN ISO 2555, and using RVT, No. 4 rotors are measured at 20rpm and 25 DEG C.

9. the method according to claim 7 or 8, it is characterised in that the solids content of the dispersion be 30 weight % extremely 80 weight %, particularly 50 weight % to 70 weight %, preferably 55 weight % are to 65 weight %, the solids content is according to DIN EN ISO 3251, is measured 30 minutes at 130 DEG C.

10. the method according to any one of claim 7 to 9, it is characterised in that the pH value of the dispersion is 4 to 7, Particularly 4.5 to 6.5, the pH value is according to DIN ISO 976, in 1 with water:Measured in 1 mixture.

11. the method according to any one of claim 7 to 10, it is characterised in that the particle mean size d50 of the dispersion For 0.1 to 5 μm, particularly 0.2 to 2.0 μm.

12. the method according to any one of claim 7 to 11, it is characterised in that the dispersion is according to DIN ISO The MFT of 2115 measurements is 0 DEG C.

13. the method according to any one of claim 7 to 12, it is characterised in that the dispersion is mostly without plasticising Agent and/or nonionic detergent, are particularly free of alkylphenol ethoxylate mostly.

14. according to any method of the preceding claims, it is characterised in that the agricultural chemicals are selected from desinsection Agent, fungicide, bactericide, virucide, acaricide, molluscacide, nematicide, ovicide, pest repellant, go out Mouse agent, herbicide, safener, fertilizer, biological agent, or their mixture.

15. according to any method of the preceding claims, it is characterised in that at least one agricultural chemicals are selected from different Metsulfovax, fluorine azoles ring bacterium amine, fluorine azoles bacterium aniline, azoles fungicide class particularly Tebuconazole, kind bacterium azoles, propiconazole or phenyl ether methyl cyclic Azoles, strobilurin classes particularly trifloxystrobin, Fluoxastrobin or ZEN 90160, pyrrole metsulfovax, metalaxyl, fludioxonil, thiophene acyl bacterium Amine, ethiprole, fipronil bisamide, Rynaxypyr, bromine cyanogen insect amide, imidacloprid, thiacloprid, Diacloden, clothianidin is killed more Mycin, ethiprole or their mixture, preferably following combination：

A. isotianil and trifloxystrobin,

B. isotianil and fluorine azoles bacterium aniline,

C. fluorine azoles bacterium aniline and trifloxystrobin, or

D. isotianil and Acetamiprid.

16. according to any method of the preceding claims, it is characterised in that the seed pelleting also includes at least one Plant colouring agent, surfactant, organic solvent and/or other polymer or copolymer.

17. according to any method of the preceding claims, it is characterised in that by the copolymer and agriculturalization Product are mixed before seed is applied to, and especially, then by the seed rice of coating with other agricultural chemicals, preferably use desinsection Agent is handled.

18. the method according to any one of claim 1 to 16, it is characterised in that by the copolymer and described agricultural Chemicals is applied to seed in an orderly manner, and it is preferred that with least one agricultural chemicals and then the seed is used into the copolymer first It is coated.

19. according to any method of the preceding claims, it is characterised in that the rate of application of the copolymer is 0.001 weight % to 2.5 weight %, particularly 0.01 weight % to 1.25 weight %, preferably 0.025 weight % to 1 weight %, Based on the weight of undressed seed.

20. according to any method of the preceding claims, it is characterised in that the rate of application of the agricultural chemicals is 0.001 weight % to 5 weight %, particularly 0.01 weight % to 2.5 weight %, preferably 0.05 weight % to 1 weight %, relatively In the weight meter of undressed seed.

21. a kind of seed rice of coating, the seed rice of the coating is coated at least partially with seed rice inorganic agent, it is characterised in that described Seed rice inorganic agent is included

A. vinyl-vinyl acetate copolymer, and

B. at least one agricultural chemicals.

22. the seed rice of coating according to claim 21, it is characterised in that the seed rice is soaked in 25 DEG C of water, Then it is unprocessed with same breed and age after the seed rice of immersion is cultivated 144 hours under 7 DEG C and 55% relative humidity Seed rice compare, show average germination percentage reduction by 0 to 10%.

23. the seed rice of the coating according to claim 21 or 22, it is characterised in that by the seed rice in 25 DEG C of water nothing During stirring immersion 24 hours, the release rates of the agricultural chemicals for 5 weight % or less, particularly 3 weight % or Less, compared to the gross weight meter of the agricultural chemicals in coating, wherein the agricultural chemicals are in particular selected from fungicide.

24. a kind of be used for the method for the newborn rice shoot resistance fungal disease of the rice plant of protection before planting and/or insect, this method bag Include following steps：

A. the seed rice of the coating according to any one of claim 21 to 23 is soaked in water, especially soaks at least 12 Hour, and

At least one other agricultural chemicals are optionally wherein applied to the seed rice in immersion and/or cultivating process, with And its described in other agricultural chemicals in particular insecticide, preferably Diacloden, imidacloprid, clothianidin or their mixing Thing.

25. method according to claim 24, wherein at 50 days or more days after the seed that will be soaked and cultivate is transplanted, Still it was observed that protection to disease and/or insect.

26. the method according to claim 24 or 25, wherein the disease is caused by filamentous fungi and/or microorganism.

27. the method according to any one of claim 24 to 26, wherein the disease is selected from rice blast (by Rice Blast Fungus Cause), paddy rice brown spot or Rice Panicle rot (cochliobolus causes by palace portion), rice sheath blight disease (drawn by Rhizoctonia solani Kuhn Rise), the bacterial blight of rice (being caused by rice bacterial leaf spot pathogenic bacteria), the bacillary Maize Ear Rot of rice (being caused by the bacillary glume blight bacterium of rice) or it Combination.

28. the method according to any one of claim 24 to 27, wherein the insect is animal pest, it is especially selected From rice water weevil, rice leaf beetles, Delphacidae, rice green leafhopper, paddy stem maggot, rice hesperiidae, rice green caterpillar, rice leaf roller, striped rice borer, Rice thripses or combinations thereof.