CN106967723B - 与水牛泌乳相关基因scap及其作为分子标记的应用 - Google Patents
与水牛泌乳相关基因scap及其作为分子标记的应用 Download PDFInfo
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Abstract
本发明提供了与水牛泌乳相关基因SCAP及其作为分子标记的应用，属于家畜分子标记领域，所述基因片段的核苷酸序列如SEQ ID NO:1所示，其中第1717600bp、1718168bp、1743088bp、1753656bp、1759116bp、1759142bp、1760740bp、1762368bp、1766036bp处分别有9个单碱基突变，且这9个SNP位点与水牛产奶性状均有显著相关。本发明公开了检测序列表SEQ ID NO:1的各碱基突变位点所需的上下游引物序列。本发明的应用，可以提高奶水牛产奶性能，为选育具有优良产奶性能的奶水牛提供技术支撑和奠定理论基础。
Description
【技术领域】
本发明涉及技术领域，具体涉及一种动物分子标记领域。具体涉及与水牛泌乳相关基因SCAP及其作为分子标记的应用。
【背景技术】
水牛是我国南方特有的种畜资源，而较低的产奶量和繁殖性能已成为了影响其产业发展的两大科学问题。显然，利用先进的分子标记技术应用于优良奶水牛种质资源的选育将会有效的提高选种效率。
产奶性状是奶水牛的一个重要经济性状，由多种微效基因决定，是一种典型的由多基因控制的数量性状。克隆奶水牛泌乳性能相关基因并探讨其遗传特性，以提高奶水牛生产性能，为选育具有高产奶量的优良的奶水牛品种提供技术支撑和奠定理论基础。
SCAP是一个内质网膜结合转录因子家族蛋白，在胆固醇稳态调节方面起着重要的作用(Horton et al.,2002)。SCAP是一个由1276个氨基酸残基组成的膜蛋白，其氨基酸末端550个氨基酸形成相互间隔的疏水区和亲水区，包含8个跨膜螺旋结构，可溶性的羧基末端725个氨基酸包含5个拷贝的WD40重复序列介导蛋白之间的相互作用(Nohturfft etal.,1998；杜静等,2006)。到目前为止，SCAP基因已在不同的脊椎动物(Nakajima et al.,1999,Qiu et al.,2006)和非脊椎动物(Seegmiller et al.,2002,Hughes et al.,2005)中成功克隆，而且众多研究已证实SCAP基因存在碱基突变影响动物体的胞内脂质代谢(Iwaki et al.,1999)、代谢表型(Cao et al.,2002)以及肥胖(Liu et al.,2014)。Dixit等(2015)发现奶山羊SCAP基因上存在9个SNP显著影响乳中共轭亚油酸含量。然而，迄今为止尚无有关水牛SCAP基因作为水牛产奶性状的分子标记研究报道。
【发明内容】
本发明的发明目的在于：针对上述存在的问题，提供与水牛泌乳相关基因SCAP及其作为分子标记的应用，以提高奶水牛产奶量生产性能，为选育具有高产奶量的优良的奶水牛品种提供技术支撑和奠定理论基础。
为了实现上述目的，本发明采用的技术方案如下：
本发明提供了与水牛泌乳相关基因SCAP及其作为分子标记的应用，所述的分子标记的核苷酸序列如SEQ NO:1所示，其中在SEQ NO:1的第1717600bp、1718168bp、1743088bp、1753656bp、1759116bp、1759142bp、1760740bp、1762368bp、1766036bp处分别有A1717600G、G1718168A、G1743088A、T1753656C、G1759116A、C1759142T、G1760740A、A1762368G、T1766036C单碱基突变，其引物对的DNA序列如下所示：
(ⅰ)获得A1717600G位点的引物序列为：
正向引物SEQ NO:2：5’-TCCTGATTGGGTCTCCACATCCCCG-3’；
反向引物SEQ NO:3：5’-TAAACATTAGATGTGCAATGAATCT-3’；
(ii)获得G1718168A位点的引物序列为：
正向引物SEQ NO:4：5’-TCCTGATTGGGTCTCCACATCCCCG-3’；
反向引物SEQ NO:5：5’-TAAACATTAGATGTGCAATGAATCT-3’；
(iii)获得G1743088A位点的引物序列为：
正向引物SEQ NO:6：5’-GGCAGGGGTTCTACGTGGAGTG-3’；
反向引物SEQ NO:7：5’-CCAATGCAGGGGACGCAGTTTCG-3’；
(iv)获得T1753656C位点的引物序列为：
正向引物SEQ NO:8：5’-TTGTGAAATCTTCCGTGTCTCC-3’；
反向引物SEQ NO:9：5’-GGATGGTCCTGATGATGTCG-3’；
(v)获得G1759116A位点的引物序列为：
正向引物SEQ NO:10：5’-AGCAGGGTCCTTAGGGTTGGAGCAT-3’；
反向引物SEQ NO:11：5’-CCGCTTGGGGAGACGCAGGTTGC-3’；
(vi)获得AC1759142T位点的引物序列为：
正向引物SEQ NO:12：5’-AGCAGGGTCCTTAGGGTTGGAGCAT-3’；
反向引物SEQ NO:13：5’-CCGCTTGGGGAGACGCAGGTTGC-3’；
(vii)获得G1760740A位点的引物序列为：
正向引物SEQ NO:14：5’-CCTGTCCATTGACATTCGC-3’；
反向引物SEQ NO:15：5’-CCAGTGTGATGTTGTAATAGCTG-3’；
(viii)获得A1762368G位点的引物序列为：
正向引物SEQ NO:16：5’-GGACGCCTCCAAGTTACCCG-3’；
反向引物SEQ NO:17：5’-GCCGTCCGACAGCCGTTC-3’；
(ix)获得T1766036C位点的引物序列为：
正向引物SEQ NO:18：5’-GTGTTCCGTCTGGAGGATTC-3’；
反向引物SEQ NO:19：5’-GACAGTCAGAAGCAGCTTTCC-3’。
所述的分子标记为水牛产奶性状的遗传标记，且与水牛产奶性状相关的SREBP1基因上的分子标记是通过PCR-DNA测序与飞行时间质谱法检测完成，而所述的应用为奶水牛的早期选育。
本发明水牛产奶性状SREBP1基因1717600bp、1718168bp、1743088bp、1753656bp、1759116bp、1759142bp、1760740bp、1762368bp以及1766036bp处SNP位点的获取方法，包括如下步骤：
a.待测水牛基因组DNA提取；
b.SNP筛查：随机取50头水牛基因组DNA进行混池，以作为PCR反应模板，利用正、反引物进行PCR技术扩增，获得的扩增产物进行测序，利用DNAStar 7.0Seqman生物信息分析软件对测序结果进行比对，获取候选SCAP基因SNP位点；
c.基因分型：针对384头水牛基因组DNA样本，利用飞行时间质谱法进行候选SNP位点的分型，根据质谱峰图判读各样本位点的基因型；
d.关联分析：利用SAS9.4软件GLM程序对水牛个体的SNP分型结果以及产奶量、奶中的总干物质含量、奶中的无脂固形物含量、奶中的乳糖率数据进行数据分析，获得与水牛产奶量、奶中的总干物质含量、奶中的无脂固形物含量、奶中的乳糖率显著相关的SNP位点。
本发明水牛产奶性状基因SCAP基因作为分子标记的应用，所述奶水牛的选育包括以下具体步骤：
①对选育水牛进行静脉采取提取DNA样本；
②针对核苷酸序列SEQ ID NO:1中1717600bp、1718168bp、1743088bp、1753656bp、1759116bp、1759142bp、1760740bp、1762368bp、1766036bp处的SNP位点，利用飞行时间质谱仪检测上述步骤①中所述的DNA样本进行基因分型，利用Typer4.0软件检测质谱峰并判读各样本位点基因型。
③应用SCAP中的A1717600G-GA、G1760740A-GG、T1766036C-TT的基因型进行判定和选育产奶量高的奶水牛；应用SCAP中的G1743088A-GA、G1760740A-GA、A1762368G-GA、T1766036C-CT的基因型进行判定和选育水牛产的奶中的总干物质含量高的奶水牛；应用SCAP中的A1762368G-GA水牛产的奶中的无脂固形物含量高的奶水牛；应用SCAP中的A1717600G-AA、G1718168A-AA、G1743088A-AA、T1753656C-TT、G1759116A-GG、C1759142T-CC、G1760740A-GG、A1762368G-AA、T1766036C-TT水牛产的奶中的乳糖率高的奶水牛。
综上所述，由于采用了上述技术方案，本发明的有益效果是：
(一)提供一种与水牛泌乳相关基因SCAP，并将其作为分子标记予以应用；
(二)提高奶水牛产奶量生产性能，为选育具有高产奶量、奶中总干物质含量高、奶中无脂固形物含量高、奶中乳糖率高的优良的奶水牛提供技术支撑和奠定理论基础。
对本发明更详细描述可参见实例部分。
【附图说明】
图1—SNP1717600分型结果展示；图2—SNP1718168分型结果展示；图3—SNP1743088分型结果展示；图4—SNP 1753656分型结果展示；图5—SNP1759116分型结果展示；图6—SNP1759142分型结果展示；图7—SNP 1760740分型结果展示；图8—SNP 1762368分型结果展示；图9—SNP1766036分型结果展示。
【具体实施方式】
实施例1：水牛基因组总DNA的制备
采用血液基因组DNA提取试剂盒制备水牛基因组总DNA(天根，北京)，具体操作步骤如下：
(1)取全血500μL置于1.5mL离心管，加入等体积的细胞裂解液CL，颠倒混匀，12000rpm离心1min，吸取上清，留下沉淀；加入等体积的细胞裂解液CL，重复此步骤一次；加入4μL RNAase(100mg/mL)，振荡15sec，室温静置5min；
(2)加入20μL Proteinase K溶液，混匀，加入200μL缓冲液GB，充分颠倒混匀，56℃放置10min，期间颠倒混匀数次，溶液应变清亮；
(3)加入200μL无水乙醇，充分颠倒混匀；此时可能会出现絮状沉淀；
(4)将上述所得溶液和絮状沉淀都加入一个吸附柱CB3中(吸附柱CB3放入收集管中)，12000rpm离心1min，倒掉收集管中的废液，将吸附柱CB3放入收集管中；
(5)向吸附柱CB3中加入500μL缓冲液GD，12000rpm离心1min，倒掉收集管中的废液，将吸附柱CB3放入收集管中；
(6)向吸附柱CB3中加入600μL漂洗液PW，12000rpm离心1min，倒掉收集管中的废液，将吸附柱CB3放入收集管中；重复此操作一次；
(7)12000rpm离心2min，倒掉废液。将吸附柱CB3置于室温放置数分钟，以彻底晾干吸附材料中残余的漂洗液；
(8)将吸附柱CB3转入1.5mL离心管中，向吸附膜中间位置悬空滴加50-200μL洗脱缓冲液TB，室温放置2-5min，12000rpm离心2min，将溶液收集到离心管中；
(9)存放于-20℃冰箱中保存备用。
实施例2：水牛产奶性状SCAP基因分子标记的获取
1、引物设计：以SEQ NO：1为模板，利用Primer5.0引物设计软件，经Oligo软件检测，确定用于扩增水牛SCAP基因的正方向引物，并委托大连宝生物技术有限公司合成，其中用于扩增所述基因的正反向引物的DNA序列如SEQ ID NO:2-5所示。
2、PCR扩增反应
随机选择50头水牛基因组DNA样本进行混池，以作为PCR反应的模板。
(1)PCR反应：反应总体积为40μL，其中水牛DNA混合池模板1μL，10×LA Taq Mix20μL，引物混合物(10mM each)2μL和ddH2O 17μL。
(2)PCR反应程序：94℃/3min；94℃/30sec，60℃/30sec，72℃/1.5min，30个循环；72℃10min；4℃保存
3、PCR产物测序、分析及分子标记初筛
将获得的扩增产物送至深圳华大科技有限公司测序。利用NCBI(http://www.ncbi.nlm.nih.gov/)网站的BLAST工具对测序结果进行分析，判定结果的真实性，并利用DNAStar 7.0Seqman生物信息分析软件对测序结果进行比对，获取候选的SCAP基因SNP位点，见表1。
表1水牛SCAP基因SNP位点
4、水牛基因SCAP的SNP分型检测
选定384头水牛个体，利用Sequenom公司的MALDI-TOF技术针对初步筛选的SNP位点进行基因分型检测，其步骤如下：
(a)DNA样品质控：通过琼脂糖凝胶电泳检测DNA浓度，纯度和降解程度；通过紫外分光光度计检测OD260/OD280数值，调整DNA终浓度在30-50ng/μL之间。
(b)引物设计、合成与质检：根据候选的SNP位点通过Sequenom公司的ASSAYDESIGN3.1软件进行引物设计，委托大连宝生物技术有限公司合成引物，通过基质辅助激光解吸电离飞行时间质谱仪(MALDI-TOF)进行质检，检测实际分子量与理论分子量是否一致，引物纯度是否达到实验要求。随后进行引物稀释：①PCR引物储备液制备：配置PCR引物储备液，终浓度为100p(μmoL/L)；②单碱基延伸引物储备液制备：配置单碱基延伸引物储备液，500p(μmoL/L)。
(c)PCR反应：反应总体积为5μL，即ddH2O 1.8μL，10*Buffer 0.5μL，Mg2+0.4μL，dNTP 0.1μL，Hotstar 0.2μL，F primer/R primer 1μL，待检测DNA样品1μL(20-50ng)；反应条件为：95℃/2min；94℃/30sec，56℃/30sec,72℃/1min,45个循环；72℃延伸/5min；
(d)SAP酶消化反应：SAP反应总体积为2*460μL，即ddH2O 1.53*460μL，SAP Buffer0.17*460μL，SAP Enzyme0.3*460μL；SAP反应程序：37℃/40min；85℃/5min；25℃/保存；
(e)单碱基延伸反应：单碱基延伸反应总体积为2*460μL，即ddH2O 0.619*460μL，10*iplex buffer 0.2*460μL，Terminator mix 0.2*460μL，引物0.94*460μL，单碱基延伸酶0.041*460μL；单碱基延伸反应程序如下：
(f)树脂纯化：将384孔板中的反应产物加入16μL三蒸水，在离心机中离心2000转离心3min；加入树脂，在反转摇匀仪上做树脂纯化反应35min，脱盐；反应完成后在离心机2000转离心3min；将脱盐处理后的样品点在样品靶上，自然结晶；
(g)质谱检测及数据收集与分析：运行MALDI-TOF-MS反应，利用Typer4.0软件检测质谱峰，并根据质谱峰图判读各样本位点基因型。其中水牛产奶性状SCAP基因A1717600G、G1718168A、G1743088A、T1753656C、G1759116A、C1759142T、G1760740A、A1762368G、T1766036C位点的基因分型结果见图1至图9。
5、关联分析
性状-标记关联分析的模型为：Yijklm＝μ+Yi+Pj+Sk+DIMl+Gm+eijklm,其中Yijklm为性状观察值；μ为均值,Yi为产犊效应,Pj为胎次效应,Sk为产犊季节效应；DIMl为泌乳天数效应,Gm为基因型效应,eijklm为随机误差。分析结果采用Bonferroni多重比较进行验证。结果表明，奶水牛SCAP基因的该1717600bp、1760740bp、1766036bp的SNP位点与水牛产奶量显著相关(P<0.05)；该1743088bp、1760740bp、1762368bp、1766036bp的SNP位点与水牛产的奶中的总干物质的含量显著相关(P<0.05)；该1762368bp的SNP位点与水牛产的奶中的无脂固形物含量显著相关(P<0.05)；该1717600bp、1718168bp、1743088bp、1753656bp、1759116bp、1759142bp、1760740bp、1762368bp、1766036bp的SNP位点与水牛产的奶中的乳糖率显著相关(P<0.05)。
实施例3：与水牛泌乳相关基因SCAP及其作为分子标记的应用
试验水牛群的品种是杂交水牛群。在水牛群中对SCAP基因A1717600G、G1718168A、G1743088A、T1753656C、G1759116A、C1759142T、G1760740A、A1762368G、T1766036C位点的不同基因型与水牛产奶性状进行关联分析。
水牛SCAP基因A1717600G、G1718168A、G1743088A、T1753656C、G1759116A、C1759142T、G1760740A、A1762368G、T1766036C位点关联分析结果见表2所示。由表2中可以得出基因型与水牛产奶性状显著相关(P<0.05)。
对A1717600G位点，携带GA基因型的水牛个体产奶量高于AA和GG型个体。
对G1760740A位点，携带GG基因型的水牛个体产奶量高于AA和GA型个体。
对T1766036C位点，携带TT基因型的水牛个体产奶量高于CC和CT型个体。
对G1743088A、G1760740A、A1762368G位点，携带GA基因型的水牛个体产的奶中的总干物质含量高于GG和AA型个体。
对T1766036C位点，携带CT基因型的水牛个体产的奶中的总干物质含量高于CC和TT型个体。
对A1717600G、G1718168A、G1743088A、A1762368G位点，携带AA基因型的水牛个体产的奶中的乳糖率高于GG和GA型个体。
对G1759116A、G1760740A位点，携带GG基因型的水牛个体产的奶中的乳糖率高于AA和AG型个体。
对T1753656C、T1766036C位点，携带TT基因型的水牛个体产的奶中的乳糖率高于CC和CT型个体。
对A1762368G位点，携带GA基因型的水牛个体产的奶中的无脂固形物含量高于AA和GA型个体。
综上，可以应用SCAP A1717600G-GA、G1760740A-GG、T1766036C-TT的基因型进行判定和选育产奶量高的奶水牛；应用SCAP中的G1743088A-GA、G1760740A-GA、A1762368G-GA、T1766036C-CT的基因型进行判定和选育水牛产的奶中的总干物质含量高的奶水牛；应用SCAP中的A1762368G-GA水牛产的奶中的无脂固形物含量高的奶水牛；应用SCAP中的A1717600G-AA、G1718168A-AA、G1743088A-AA、T1753656C-TT、G1759116A-GG、C1759142T-CC、G1760740A-GG、A1762368G-AA、T1766036C-TT水牛产的奶中的乳糖率高的奶水牛。这对于组建高产奶水牛核心群具有重要意义。
表2 SCAP基因9个SNP位点与产奶性状关联分析
注：同行数据，不同字母表示差异极显著(P<0.05)；相同字母表示差异不显著(P>0.05)以上所述实施例仅表达了本发明的几种实施方式，其描述较为具体和详细，但并不能因此而理解为对本发明范围的限制。应当指出的是，对于本领域的普通技术人员来说，在不脱离本发明构思的前提下，还可以做出若干变形和改进，这些都属于本发明的保护范围。因此，本发明的保护范围应以所附权利要求为准。
SEQUENCE LISTING
<110> 广西壮族自治区水牛研究所
<120> 与水牛泌乳相关基因SCAP及其作为分子标记的应用
<130> 2017
<160> 1
<170> PatentIn version 3.3
<210> 1
<211> 93104
<212> DNA
<213> 水牛种
<220>
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<400> 1
tgtgtctcct gcattgcagg cggattcttt actgctgaac cactgctgcc tgagggaacc 60
gcagtttgag agccctggct ctaaaaccag agcacgaggt cagtgttttc atgtttcact 120
tagaatctca tcagcatcgc cttagttttg ccaagctcgg gcagtcctct gaattaatga 180
tgactcaact taccattttt caacgatatg atggtgccaa agcaatcata tattcagtag 240
aaaccatgct ccaaattttg aatttttaat cttttcaggc ctgtgatatg ttgacagcca 300
cactcccgtg atgctggaca gcagcattga gcccagctcc cagtcagaca cgtactcatg 360
ttcagttcag ttcagtcgct cagtcgtgtc tgactcttta ggaccccatg aatcgcagca 420
tgccaggtct ctctgtccat ccccaactcc cggagttcac tcagactcac gtccatcgag 480
tcagtgatgc cgtccagcca tctcatcctc tgtcatcccc ttctcctcct gcccccaatc 540
cctcccagca tcagagtctt ttccagtgag tcaactcttc gcatgaggtg gccaaagtac 600
tggagtttca gctttagcat cattccttcc aaagaacatc caggactgat ctccttcaga 660
atggactggt tggatctcat gagggtgacc aactaataca attagagcca ttctgtattc 720
agacaaccat tttttcattt tggtattttg gtatttttca gtatggtatt cagtaagtta 780
catgagatat tcaacactat tataaaatag gctttgggtt agatgatttt gcccaacttt 840
aatgtcagtg atctgagcgc atctaaggta ggctaggcta agtgatgaca ttcagcaggc 900
tgggtgcagt aaatgcaatt tcggcattgc agtgttttca gcttaggatg ggcttatcag 960
catgtacctg gaggagggca tggcaacctg ctccagtgtt cttgcctgga gaattccacg 1020
gacagaggag cttggcaggg tacagtcatg gagtttccga gagtcggaca caactgagcg 1080
actaacacac acacacgcgt gcgcgcgcgc atcaggatgt gcctccactg taaactgagg 1140
aagatctgtg tgtatctggc tcttggtttt agtccatttc tttcttattt gtagataatg 1200
tcataattat attctcaact gtagtgctgt ttctgctttc cctgcagttt ctaggttgag 1260
gaattagagt tgttgtttta attcgaatca ctcatcttct taaaaattga taagctcacc 1320
catatgcgcg cacagaattt acattgtctg taatcccagt ggtaaccacc tgcagggttc 1380
ttctcaggct tctttcttgc tcattcttat tttctttctc tgtgtaatgg gttcatactg 1440
ttctgtatcc attttctgtg tgaacatttt tttcatgtat aaaactgttg tagaacattt 1500
ttgatttttt ttaaaaaaca tgggctctca tttattttga tgtttttcag tggctttccc 1560
tttgagcagc cttgtccagt ccagcctgct acatgtggct gtgggcttcg tttgcacctt 1620
tcagaaggct gtgctgtcac tcacaaagtc ttcaatcatg gtctctcttt ctcaacaatc 1680
ttcagtagct ccccactctt ataatctgcc ccaggctggc acatccaccc cttcttccct 1740
ctgccaggca gtgtttatgc tgccttatct ttattttttt tttgtaagag gccacttgga 1800
tggaagaatt tttaaaataa atttattcat tcatttattt ttggctgtgt tggatcccct 1860
cgttgcagtg agtgagggct acgctccagc tgccacgtgc gggcttttca ctgtgggggc 1920
ttctcttgtt gctgagcaca ggctccaggg tacccaggct tcagtagttg ggacacatgg 1980
gctcagcagt tgaggctctt gggctgcaga ggacaggccc aacagttgca gtgcacaggc 2040
ccagttgctc cacggcacat gggatcttcc cagaccatgg attgaacccg tgtctcctgc 2100
attgacaatt ggattcttat ctgttgagcc accagggaag ccctgtgctg tcccagcttc 2160
agggagcgat tagttctcat ctttcaggca tgagccctgg ttgggtttga cattcattct 2220
cagttgtccc cccagcaaca gtgactgtta ggaatatcaa gacctgcctt cagcaggcag 2280
cagagaatgt tgcatctcat attcttgtca ggaggataaa agctgtcctg aactcagctg 2340
tggtaaagga tgtccatggg gttgttctgg cacaggctcg gtgcacctgt tccaggcagt 2400
gttttttctt tgaatgaaac tggatcatta gcatatttct ggcctccttc cgcttcacac 2460
ggccccatca gcttgtgtta agagctgtac aagaagcctc caagaaaatc tgtgagtcca 2520
attagaaatt gccttcaggt ccagtgcctg ggagtggtca tgcctcttct gaaccattga 2580
tttgattttg tttaaaccat actgtgaact gtgtcagaat ggttctctct ttgcctgggt 2640
tcctagggag ctcatagtct catttatatt gagagttctc tggcttgtgt gttcttctgg 2700
cttataacat tgtttttttt ttctttttaa tggctagaca ttttgctctt tctctcaaat 2760
tttaccataa aaaacacatt tcatgtcttt tctaaacatt acagtgatta cattcttgtc 2820
tccaaatctg tcttgctatc ctatatcctt tcattttttt tcatacactt gaatccctct 2880
gaagcctgct ttcgcttgcc ccctgccatt tcctcattgt tttttgttgt tccatttttc 2940
tcttgtggta aatatacaag tttccatatt aaccatttta agtgtacagt tcagtgatat 3000
taaaaaacat ttataaattt tcacaacatc accaccattc tttctgtgat gtggatagtt 3060
gtgtctgact cggcgacgcc gtgaactgta gcccacctgg ctcctctgtc cttgggattc 3120
tgcaggcaag aatactgaag tggtttgcca tgccctcctc caggggatct tcccagccca 3180
gggatcaaag ccaggtctcc cgcattgcag gcagattctt tactttctga tccaccaggg 3240
aagcccaaga atgctggagt ggatagccta tcccttctcc aggggagctt cctgagctag 3300
gaagcgaacc gggaccttct gcattgctgg cggattcttt accagctgat ctaccgggga 3360
agcccattct ctctgtatct ctcctcattt tgcaaaactg aaactctata tccattaagt 3420
agtaactcat tttctcctct cccaagtacc tggcagtaac catcctaaat actttatata 3480
actatgattt tgactaagta tatcatgtaa atggaattat accctgttac tctcttgtga 3540
ctggtgtgtt tcatgtagca taatattctc atgttgtagc atgggtcaga attacttcct 3600
ttttaaagct gaataatatt ctgtgtatac ctcattttgt ttatccattc atctgttgat 3660
agacattttt attgtttcca ccttctggct gttgtgagta atgctgctga taacttgggt 3720
atacaaatat tagttcaagt ccttgttttc agttctcttg ggccagtatg gaagtggaat 3780
tgctggattg tatggtaatt ctatgattca tttttttgga accatcagac tgttttcccc 3840
agaggctgta ccattttaca ttcttgccag caatgcacaa gggttccagt ttcttcacat 3900
ccttgctaac acttgttgtt ttctcatgtt ttgatagtag ccattgtaat gcctatgagg 3960
tgattatctc tctttgtagt ttttataaaa tatttttttg gtgaacaaat ttcttaaaag 4020
atcacttaaa atcaacatag aaaatggttg catagtacag atctcaacta ttcactcaga 4080
atacatttta agaataattt tcttttatta tatataaaca tttattttaa taatactctt 4140
tatcacttta acttacatca ttccagtgtg aaaatgtttc attgaagaga gaatatttct 4200
tcagaactct aaataaagag ctttaccgat caaatttgcg gagcacagtc tttagaaaaa 4260
tgaagttgtt cattttgcgg taatgcttcc cctttaaaca tctgccagtt tgtcacaggt 4320
ttcaagtaca aggtgcctaa tgctctgaac gtgtatgtag tgtaagcgaa ccaaagcttt 4380
tctcagatat caattctttg taagtcctac aaatttgtgt gaatgtattt gttgtataaa 4440
ataaatattt tttcctgttg ttaatttgta atattctata aaactcagat atattcatat 4500
ctatcatggg cagcttattt tagcatttta cctgtaaaaa acactgatct atatacttaa 4560
aatgatttct tgaaaaaaca ttttctgtaa tatagtccag catttaacaa ataatacaat 4620
taaaatttat cccttgatca gtattcagat taagagtaat tttcttaatg tttgcaagtg 4680
aagacttatg acctgagata ggatccgttg acagcatcat acactgattc agaaagatat 4740
cttcagtaac taaggcggaa gtggaagtgt actctagaag atatgagcct agaagagagc 4800
agcatttcta aatctcattt tacatgtgta ctttgaaatt tattatagca taagcagttt 4860
aacaattaaa tatcataatc acagagttga cctttttttt tttaatattc ctgaagttca 4920
tgtactcaat ttgaccttaa aaccttttaa aagtattcat aatttaaatg gtaagtactc 4980
atatgtacac ccatggctga ttcaggtcaa tgtatggcaa aacccactac aatattgtaa 5040
agtaactagc ctccaattaa aataaataaa ttttaaaaaa atggtaaaga ctgccttaaa 5100
tttgtgctta tacagtttat aaaatggatg aaagagacaa cagagcagat gtctaataaa 5160
ttgatgtaag gtcgcagcaa tatgtattta agtatactgg catctgctta aattcacgaa 5220
gaaagaaatg atgagtctgt attctgaacc cgcaacctag tatcgattgt gtgtgtgcgc 5280
gctaagtctc ttcagtgtgt ccaactcttt gtgaccctat ggactgtata tagcccacca 5340
tgcttccagg caagaatact ggagtgagtt gccatgccct cctccagggg atcttcccca 5400
cccagggatt gaacccgtgg ctcctgtggt tcctgcattg caggctgatt ctttacctct 5460
gagctgccag ggaagcccag tattgattgt atattgtctc aaattactag ccccctgctt 5520
cacttcacgt tgctaaaccc tgccttccta aatgtttata aatggtcagg agtctggatt 5580
gacacagttc agtggtgagt ttttgttttt gtctttttaa ccccagcagc tgtagcacta 5640
gcactgtcct cggttcagag caagttctgt taatatttct gaagtgtttt ccgtggttgc 5700
tattgactca ttgtaatttc agtttgcatt tccctagtga tcagtaatgt tgagcatatt 5760
ttcatgcttt tattagccat ttgtatatct tctttgggga aatgtctgtt caagcccttt 5820
gcccattttt taatcagatc actttttaaa aatttttatt tatttgtttt taaacttcta 5880
actttgtatc agatttttct gttgttgagt tctaggactt ttctttatat tctagatatt 5940
aatcccttgt caaatatatg atttttaaat attttctccc attctgtggg ttgccttttt 6000
actctgttga tagtatcttt gtgtttttgg tccatgctgc acaaccaggg atctggggcc 6060
tcggaagtga gtatgcagag ccgtagccat tggatcccgg gaagttctct gttgatagtt 6120
tcttttgatg cacacaattt aaaaattttt atgaagttca gtctgtttac gtttcatttg 6180
ttccctgtgc ctttggtgtt ataccaagga attgtcaaat ctaacgtgaa gcttttgccc 6240
tttgttttct tttaagagtt tttatagtct taagttcaga tctttgatcc ttatgtattc 6300
attgctgcta aattttgtaa aggggtacat tctgaaaaag ccttgtacat ttcaaaggac 6360
ttctctgcct attaatgttt attatcatta aattgaaata tacacaaaag cagagagtag 6420
tgatccattg tgatgtatca cttagttatg tctcatcctt accaatactt atttcttggc 6480
tacgccacac agcatgtggg gtcttagttc ctccaccagg gatcgaacct gcacccctgc 6540
attggaagcg cagtcttaac cactagactg ctagggaagt cccttttatt ttgtgggggg 6600
tactttaata attgtgcatt cacataactc ccagaaccag actgaaaaga aatagtgcat 6660
tgattataca tatacagaac atacatacag tgtatgttgc atataaagta ataacagtga 6720
tttccctcca aattccttaa tacattttct caaataatat gtcttagttt ttagatgaat 6780
tgcaagcaca gtcatgtgtc ctgacacttg ttatttttct tttttttaag aaataagagc 6840
caacctattg ggtgtgaagt gatatgtcat tatggctttg atttctattt ctgtaatgat 6900
tagtgatgtt gagcagtttt atgtgccttt tgatcattta tattcaatgt atctattcaa 6960
gtcctttgcc cttttttttc tttttttggc catgcagcgg gcacatggga tcttagttcc 7020
ctgaccgggg atcaaaccta tgcccgttgc attggaagca cagagtcttt cggaccccta 7080
gggaagtccc tacttaccca tttttgaatc gagttttttg ttgttgctga gttgtggcag 7140
ttctttctat attctggata ttaatctctt cttagataca tgacttgcaa atatattctt 7200
ccattctgtg ggttgttctt cactctgttg atagttttct ttgaggtaca aaagtgattt 7260
tgttatctgt tgttgttgtt gtttttctgt gcttttggtg tcacatccac aaaatccttt 7320
cagaatcagt atcatgaagg ttttacccct gtttttaaga gttttattag ttctagttct 7380
ttgtttaggt ctttgattga ttttgagtta gtttttgtat atgatacaag ggtccacttg 7440
aacttttttg tgtggggctg tcatgttttc ccagcaccag ttgctgaaaa aacttttacc 7500
aggtgtccct ctcatctctt ggctctcttt ggcactctct ccctcacaaa caggtcttct 7560
gcatgttttg tgtttggaat gcaaccatct tccatgtggt gtttatatta aaagctcttg 7620
agacagtaat aaaatctaaa ctcatcacac cttcactttt gagaaaactc tcaagaagca 7680
tggtactttg cagaagaaca cacttctctc aggaagccac aggcaagagg cttccgttct 7740
gtgaggtctg gacataccca tgtgtggctg agagcaggag tctggtcctg gccatgcttc 7800
tgagaccaag gctgagggca ccctacctct gggcctgcag tcttacgaaa tgacagggct 7860
gccctattga actcctgtgt tgtttctagc tttaaaacat tctttgccca tgttcttagc 7920
agtcagttca gtccatttgt tagtcattgc tgaccacgtc aagagggaat gaaaatgtag 7980
gttgctggtg ttgtggaaga aagtcttcaa tgtatctgtt gatgctgaat tgtgcagagg 8040
agtcagcatc ctgtaatggt tttttgcgat gatcatcaca accgtttaac ttagtcttcc 8100
ttcaatacga gtattgctgc gccatcccaa caattatcct aattgtggca atagtcatcc 8160
tcttgaatat gatgttttca ggcttcaagt tctttgaaat cagctttcgt tcgttaactg 8220
aaactccttt cttttttcag tactgttaat ttaagtctgc tgaaaatcct tccagcttat 8280
ttgggtaatt ttaatgctta gagaagcaga atttcctgtc ctgatcattg atccactttc 8340
caaatcaact tgccctccaa agatgaattc tttgcaccag tggactagtt tagcacagtg 8400
aacagaccta tagtgacttt ccttttggca ccaaaggagg tgctgaccac tctagggaac 8460
acaaaggtga ttcagccgtg acctcccagg agggactgca gtcagtcagg ggaggctggg 8520
aaagtcagaa taaacacagg gccaagtgga aatacagtta cagaagctca gaatagaagg 8580
ctgctgctcc tagaaggagg ctttcatttt tttttttttt taattttagc ttttcagggc 8640
agtactgtat tcacatagca caaaatttaa aaggtacaac agggtataca ccagaacgtt 8700
tcccttccat cttgcccctg gccaccagat ccttttccca gaggcagcca gagttacaag 8760
ttctcgagtg tctgttcagg cctgttctgt gcataataca gacgaacaca cagagagctc 8820
ctttctttta catgaaaagt agcacacttg ctcttttctc tgtttgtgat agatcattgt 8880
caatacggaa gagcttttta ttgtctttta caactggaga atattccatt gtcaggatgt 8940
acttttattt agccagtgct ctatggatgg atatgtaagg tgttttacat tttgctaatg 9000
cagacaccgc tgaggcgcgt tctgtataca tcagtccacg catggccaag ggtgtgtgtc 9060
cattcactta cctgaggcag gagcgctggg aggtgagtat gtgcttctgt ggttttgata 9120
gctcttacaa gttaaacctc cgtagaggtt ttgtccactt aggctcccag ccagtttggc 9180
agtgcctgtt tatccacacc ctcaccaaca ctgtgatatc tcacagtttg gactttgcca 9240
gtttttttgt ttgtttttaa atttatatat ttagccgttt cgagtcttag ttgcagcaca 9300
ggggatcttt gttgcatcat atggtctctc tggttgtggc tcagtggctc agtggctgtg 9360
actcgcgggc ttagttgctc cgagtcctgt gggatctagc ttctggacca gggatcaagc 9420
ccgtgtcccc tgcattgcga ggcagatttt taactgctga atcaccagga agtcctgatc 9480
tttgccagtc tgttagctta aaaaaactag atttttttcc tccaaaactt cttagttcat 9540
cctgtagcaa agttaaggtt taagggccat tttagttttc tgtgaagtca gtttgtatcc 9600
ttggcctgtt tttctactgg gctttggtgt ttcttaattt tgtaaaaaaa aaattatata 9660
ggaagaaact ttgcattttg tcagtgatag gaattgcaat tatattttta tagattttaa 9720
aatatttttt tattgatact taggatggtt ttgtcatgaa aaaaaaattg atttttaatt 9780
gactttttaa ggcttatggg ttctctgtca tacatagaaa gatattccct ggtagaagtg 9840
tatgaaaaat tatcctatgg tttcttaaag tactttttat gtttcatttt ttacctttta 9900
tccatttttt acctttttac cttttatgtt tcatttttta cctttatcca tttggaattt 9960
tttttagtat gaagtgtggg tccaatttaa tttttcccaa ttggctgctc atttgttgaa 10020
atacctttta ttgaacaatt catcttttcc ccacttcttt aaatatcctt tatcatttac 10080
tatgtatgat gtactttgcc acatatcatg tatattgggt ctatttctag actttcaatt 10140
gtagatatta atccatgttt taatgtgttg gtatcatatt gttttagtta ccctagtttt 10200
atagcatatt tcagtgtttg gtaaagtaaa ttctaattca ttatctttat ttttcacaac 10260
tttccttgct gttttttgtt tttctttatg aactttaaga caagtttgtt tgttgaaagt 10320
cctgtttgtt tttattggga ctaaattaca gttttagctt agtgtaagaa aagtgacatt 10380
ttgatgatga atcttccctg ctaagattac atggctttct ctctgagttt ggttttagtt 10440
ttgatggatt tcttaataca cttggatttt atgccaactg tattctcagg tctttcttgt 10500
ttgtttttaa tgctgaagca tattcccttc tgtctacttg atgatgatgt atgtggaatt 10560
gttgatttgt atatattaat tttcatcatc ttacctgatt tttaattaat tgtgataggt 10620
cttcagttgc ttctcttgga ttttttaggt ttataatatt atccacaaat aaatgtttgc 10680
tctggttgta cacctgtgtc ttccttctgt tgtcttttgt gatgggtggc tcctccacag 10740
cagtggtaaa cactggtggt gaggtgcgtg gctttgtttg gcctctgact ttggtgggaa 10800
gtcttctaat gtgttcccac tgcacttgac tttagctttg agattgagaa ggatgtaaat 10860
atgtggttga tgtctgtatc ttactgtata tttttaaatg taaatatgta tataaatatt 10920
caagcttttg tcagtttaat taaagtgtaa ttaacaaaat tgtgtttatt taaagtatac 10980
aacatggtaa tttgacatat gtgtattttg tgaaataatt accacaatca ggttaatgaa 11040
cacatccatc acctcagttg ccttttttct tttctttgta gtgagaatcc ttacagtctg 11100
ttctttcagc agttttcagg cactcacagt attgttgact gtggtcactg tgctgcatgt 11160
taaattcccc agagcttatt catcttatca gggaaggctt ctgccctttg accagcatct 11220
ctccatctct cccaggccct ggtgaccacc attctactct ctgtttctgt gagttggaca 11280
cttttttttt ttagattcca cttatgaggg tgatcataca gtatttgtct ttctggctga 11340
tttcacttat tatcgtgtgc catagattct tccacgttgc tgcaaatttc agaatttcct 11400
tctttcttgt gactagttaa tatgttaata cacacaaccc taccttatct gtttatctgc 11460
tgatggacag gtaggttgtt tgcatatctt ggctattgtg aataatcctg aactgagcct 11520
aggcatccag ataatctctt caagaaatga tatctttgga tgtatgcccg taagtggaat 11580
tgctgggtca tatggtaggc tgatttgttt ttttttgttt ttttttttta atttttattg 11640
gagtacagtt gctttatagt cttatgttag tttcaggtcc acagtgaagt ggatcagtta 11700
tacgtatatc cactcttttt tagattcttt tcccatattt aggctggtac agagtattga 11760
gtggagttct ctgtgctcta cagtagatcc tcattagttg tctgttttat gtatagtggt 11820
gtatatatgt caatcccaat cctccaattt atccccctgc tcttaccctc tggtaaccat 11880
tagttgtttt ctacatctgt agctctctgt tttgtagata agttcatttg taccctttta 11940
ttagattcca catataagca atattgtatg attgtctgac ttcactcatt agaacaatct 12000
ataagtccat ccctgttgct gcaaacggca ttatttcatt attttgaact gaactaactg 12060
aactgattat tcagattatt attattgtat atatatacta catcttctaa aaccattcat 12120
ctgtcgatga gcatttttag gttgcttcca tgtcctggct gttgtaaata gtgctgcagt 12180
gaacactggg atgcatgtat cttttcaaat ggttttttct ttgtatatat gcctgggagt 12240
ggggttgctg gatcacatgg tagctctgct tttatttttt taaagaccct ccatactgtt 12300
ttccatagtg ctgtccactt tacattccca ccaacagtag gaaagttccc ttttctgtgc 12360
acctgctcca gcatttattg tttgtagact ttttgattat ggccattctg acccatctga 12420
ggtgatacct cattatagtt ttgaattgca tttctctaat aattagtgat gttgagcatc 12480
ttttcatgtg ctttttagcc atttgtatgt catctttgga gaaatgtcta tgtagatctt 12540
ctgcccgctt aaaaacatta tttgtttttg gctctgcttg ttgttggttg cggtgcaggc 12600
tttcctctgg ttgcggctgg tggggctgct ctctagttgt ggtgcatggg cgtctctgca 12660
ggggcttctc ttggtgcaga gaatggcttc tagggtgtgc aggtttcagt agtgcaactt 12720
gtggctcagt agcgctgtct cctgggctct agagcacggg cccactgctc tgaggcacgt 12780
ggggttctcc cgcactggca cgtgggctct tcaccactga accacaggga ggccccatct 12840
tctgcccacc ttttgactgg gttgtttttt gatattgcac ttcatcagct gttaatatat 12900
tttagaggtt gatcccttgg ttccttcact tgaaactatt tctcccattc tgagggttgt 12960
ccttttgttt atggtttcct ttgctgtgca aaagcctttt agtttaggtt ccgtttgttt 13020
atatttgttt ttatttattt tctttaccct aggaggtgga tcaaaaaaga tcttgctgca 13080
atttatgtca aacagtgttc tgcctatact ttcctttaag agtcttataa tatccagcct 13140
tacaaacagg tttttaatcc attttgagtt tattttttgt gtaaagtgtt agggagtgtt 13200
ccagtttcat tcatttacat gtagctgtcc agttttccca gcactcctta ctgaagaaat 13260
ggtagtttgg tttttaaatt ttgggggaat ttccattgtg ttttccataa tggctgtacc 13320
aatttacagt tccaccagca gtgtacaaga aacccctttc tccacatcct tctcttcttt 13380
attgaaacca tcctaatagt gtgagatgat gtcttattgt ggttttgatt tgtatatctc 13440
tgattaatga tgttgagcat ctattcatgt accatttgtg tacattaatt ctttggaaaa 13500
atgtctgttc tggtccttta cccatttctt aatcaagtta ttttgttttt tgttttgctg 13560
ttgagtggta tgtgtttgga tattaatccc ttatcaaata tatggtttgc aaatgttttc 13620
tcccagtcca tacattgtct attcatttta ttgattgttt cctttctgtg tagagccttg 13680
tactttaatg tagtattgtt ttggccaaaa agaagtttgt tctggttttt tcatgataca 13740
gaaaaaccca aatgaacttt atgccaacct aatacttttt ttctttactt tttttttttt 13800
tggcctgtgc attgccagga ccagtgtcaa ggagcatatt ctctatgtaa ccttctagga 13860
tttttatcat ttcagatttt acacttaagt ctttgacctg tttaagttaa cttttgtaag 13920
tggtgcaagg gatcaccact gacataggga tccagttttg ttcttttgta tgtggatatc 13980
ctgttttcca aacaccattt attgaagaga ctgtccattc tccattgtat attcttggtt 14040
ccttgtcaaa gattagttga ccctacatat atggtttata gcagaactta accgctgtgt 14100
tccactggtc tgtgtttctg tttttttatg ctagtaccat actgtcagat tattatagca 14160
tatgatgcct gtaactttac tgctctttct caagattgct ttggctcttt gggatctttt 14220
atggttccac acaaattata ggattatttt cttgtttctg tgaaaaacac caatggaatt 14280
ttgatggagg ttgcattgaa tctagattgc ttgggtagta tggacatttt aacaatattt 14340
ttccaattca tgaacttgga atttttttct atttatttct atcttcctca attcctttca 14400
tcagtgtctt atggttttca gtgtgcaggt cttttatctt cttggttaca tttgttctta 14460
agtcttttat tctttttgat catactgtaa atgggattgt tttctggttt ctttttctga 14520
cagtttgatg ttaatattta ttgggttggc caaaaagttc ctttggattt ttctgtaagg 14580
cgttacggaa aagctcgaaa ccttttggcc aacccagtag aaatgcaggt gactgttgtg 14640
tattgatgtt atatcctgcc accatactga atttatcagt atgaatagtt ttttttggtg 14700
gagtttagga catatgatca tgtcatctgc aagcagagac agttttattt cttcctttac 14760
aatttgagta ttaaaattct attttcctgc ctaattgatt tgactaggat ttccagtccc 14820
atgttaaata gaagcagcaa tagtggggac ccatgggaat tcccagggct ttcctgatag 14880
ctcggtaaag aatctgcctg caatgcagga gactcccatt caattcctgg gttgggaaga 14940
tccgctggag aagggatggg ctacccactt gtgtattctt gggtttccct tgtagctcag 15000
ctcataaaga atccgcctgc aatgagggag acctgggttc gatccatgag ttgggaagat 15060
cacctggaga agggaaaggc taccctttcc agtattctgg cctggggaat tccaaggact 15120
gtatagtcca tggggtggca aagagtcaga catgactgca caactttcac tttgatggga 15180
attccctggt ggtccagtgg ttagaactcc atgctcttaa tgatgagggc ttgagtttaa 15240
tccctggtca gagaactgaa atcccacaag ccacatggca cggccagaaa aaaaaaaaag 15300
taatggacac ccttgttttg ctccagctct tagaggaaaa acgtttggct tttcaccatt 15360
gatgatgatg ttaactgtgg gcttgtcata tatggccttt actatgttga ggtacattcc 15420
tttgttccca gtatgttgag agttttttct tatcatgaaa ggatgctgag ttttgttacg 15480
ctttttctgt atttgttgat aatcatagga tttttgttct gtgactgtgt agtatcacct 15540
ttattgattt gcaagttgag ccatctttac attccagagt aaatcctctt ggtcatggtg 15600
tgtgatcttt tttaaataat taactaactt atggctgtgc tgggcctttg ttgctgtgct 15660
cagtcttttt ctagttgcag tgagcagggg ctactcttcg ttggagtgcg caggcttctc 15720
atcgcagggg cttctcttat tacggagcac aggctgtgta ggtgttcagt agttctagca 15780
cttgggctta gtagttccag cacatgggct cagtagttgt ggctcagctg cttcgtgaca 15840
tgtgggatct tcctagacca gagatcaaac ccatgtcccc agcattggca agcggattct 15900
taaccactgg cccaccaggg aaattctcta tcaggaaagt gtgtgatctt ttcagtgtgc 15960
tgctgaattt agtttactaa gattttgttg agttttgact ctctttttgt cagggatatt 16020
gtcctataat tttcttttct cacagtgtcc cctatctggt tttggtatcg gggtaatgct 16080
ggcctcttaa aatgagtatg gaaaagttcc ttcctcttca gtttttttgg aataatttga 16140
gacagattgg cattaactcc tctttaaatg tttggtagaa ttcactagta aagccatcta 16200
gtcttgggct tttgtttgtt gggagatttt tgatttctca ttcagtctct tctggctttc 16260
ctgatggctt agatggtaaa gaatctacct gcaatgcagg agacctggtt ttgatccctg 16320
gatttgggaa gatcccctgg agaagggaat ggctgcccac tccaatattc ttcccacccc 16380
tcccccccaa atgtcataaa ttttttaggc aaaaaatcat aagtttttaa atatatataa 16440
aatgcatatt atttatgtat acaaaagctt ttctgctatg cttgataaag gcttgagaaa 16500
gaacatcaaa aacaaaagaa atgatggaaa atttgtaaaa tataaactaa atgaaatggg 16560
agccttgaat agaagaggtg aaacaaacta gataaaagta aaagatcatc gtatagtcca 16620
gttgttctta aacatggctg ctcattagaa aggtatctgg agctttggag agggaaaaaa 16680
gcagtgcctg ggcatttttt tttttttttt taattccaag ataattctga tatgcattgg 16740
gttttaaaaa gtgattacaa ctttttctat tgaatggtag ttttagtgat atagaattct 16800
attatttttc tgttgaccaa tcatgataca gtggtattat gtgagtaata gttacataat 16860
cacaatagta aaagattttt atcagttttc acagtcaata gccagacaaa aaataaaagg 16920
taattgcagt tgcaggtttt tgttctagct gctgtgggat tgtgactctt cttgtttctt 16980
ctgtctgcct tctgatggag gaggctaaag ggcttgagta accttccaga tgggagggac 17040
tggctgtggg gaaaaactgg gttttgccct ggtgagctaa tccagttatc tgctgatggg 17100
tggggtttgg cctgaggtga cccaactctg gcatctgcag gctctatgat agggttaatg 17160
gtgacctcca agagggctta ctccaagggg aatcttccag gactgttatt gccagtgctc 17220
ccatccctgt ggggagcccc tgctgacccg cacctccaca ggagaccctc caacactagc 17280
aggtggtttt gatcagtcac ctgtagggtc actgctcctt tgctctgggt ctcggtacgt 17340
gcatgatttt gtttatgccc tccaagactg gagtctctgt ttccctcagc cctgtggaag 17400
tcctataatc gaatcccgct ggccttcaag atcagattcc ctggggactc ccagttccct 17460
ttgttggatc cgcagtctgg gaagcctgat gtggggttca gaaccttcat aactgtggag 17520
aacttctttg atttattgtt ctccagtttg tgggtcgccc acaaactggc agttacggaa 17580
tttgatttta tcatgattgc aaccctccta ccatctcact gtggcttttt ctttgtcttt 17640
ggatgttgga tatcaggatg atggatcctg ccagtcgata gttgttcaac ggctagttga 17700
gattttggtg ctctggcaga agatgagtgc atgcccttct actctgtcat cttgaaccgg 17760
aagctggaac tacccaactg cagtatttgt gccggagaat tctgtggaca gaggagcctg 17820
gtggactaca gtccatgaag tcacaaagag ttggacacaa ctgagtgact aaaactttca 17880
gtcttttcac tagtaatcag cctgttcaga ttttctattc ttgatttagt cttattggtc 17940
gtatatttct aagattctat tcattacttt ttggttgtca gttttattgg catctaattt 18000
ttcatagaag tctctcagtt cagttcagtt cagtcgctca gtcgtgtccg actcttcgtg 18060
acccggtgaa tcgcagcacg ccaggcctcc ctgtccatca ccaactcctg gagttcaccc 18120
agactcaggt ccatcgagtc agtgatgcca tccagccatc tcatcctctg ttctcccctt 18180
cttgtcctgc cctcaatccc tcccagcatc agagtctttt ccaatgagtc aactcttcac 18240
atgaggtggc caaagtactg gagtctctat gatcctctat atttctgtga tatcatctgc 18300
tttcatttct gattgaatcc tctcttttgg tgagtctaga taaaggtgtg tcagttttgt 18360
cttttcaaaa aaacgagctt ttggtttcat tcatcttttc tgttgtcttt ttagactgtt 18420
tccgctctga tctttgttat ttccttcctt ctaagtagaa ggcttagttt attctttttc 18480
tggttcttga ggtgtaaagt taggttgtct atttgagata gttctttttt ctaagcatag 18540
acctttatta ttataaactt tcctcctaaa actgcttttg ctgcattcca taagttttgg 18600
tatgttgtgt ttccattttt gtatcatgat gtttaaaatt ttttaaattg tcttttgatt 18660
tcttctctaa tccattggtt cttcaagagt ttgttgctta gtctccacat ttgtgaattt 18720
tccattttcc ttcctgttac tgattcctgg tttcacacta ttgtggtcag aaagatgctt 18780
ccttgtttaa gtattgctgt cttggccgtg tcaggcctta gctgcttctg cagggcctcg 18840
agttgcagcg ccagcctctg cctcgtggtg gtgcaggctc agtggtcgca gtgcacgggc 18900
tcagttgctc cttggcatgt ggggtctgag ttccctgatc agggatcaaa cctgcatcgc 18960
ctgtattgca aggcgaattc tttactggac caccagggaa gtctgtcctt cattcttaat 19020
acattttcta agacttgttt tctggcctaa ctcaggatct atcctgaaga acgttccgtg 19080
tgcgcttgag aagaatgtgt gttctggtgc tgtttgcatg aaatattttg tgccatgtat 19140
gtctgatggg tccatttgtt ctggagttta gttcaaattc aaatgcttcc ttattgattt 19200
tctgtttgga cagtctctgt tttgttgaca gtggggtata gaggtcccct actgttcctg 19260
tattgtcttt ttctcccgtc agatctgtta gtatttgttt aaaatattta ggtgctctga 19320
taatgggtgc gtgtgtattt acaagtgtta catcctctga tgaattgact ttgttttcat 19380
tatatagtga ccttttttgt ctcttgtcca gctttaaaaa gtgtttttgt tcgttttgtt 19440
ttcgtttatc tttggctgcg ctgggtctcc gttgctgcac atgcttttct ctggttgtgg 19500
tgagcggggg ctgtgctctt gtcgtggcac atggtcttct ccctgcggtg gttcttttgt 19560
tgcagagcac gggccctgga gctcactctt ggtagttgtg gctcatgggc ttagttgctg 19620
tgtaacatgt gggatcttcc tgggtcaggg attcaaccca tgtctcctgc cttaccaggc 19680
agattcttta ccagtgagcc tcccgtgaag ccctcttgtt aagtttttgt ctggtgtaag 19740
tatagccatt tctgctttca tttggttttc atttgcatga aatatctttt tccatccctt 19800
cactttgagt ctttttgtgt ccttaaagct aaattgagtc tctttgaata gatataaata 19860
tatttatagg tagatagata gatataaaca tataaaatgt catctggtta cctgtgctaa 19920
taaagtttct ccttgatgat gaaaaaaaaa aagctaaatt gagtctcttg tgggaagcat 19980
atagttgggt ctattttttt tttttaatcc attcagctac tgtatgcctt ttgaatagat 20040
ggatgattta aagaattaaa atttaaagta attattaata ggtaaggatt tactaggtct 20100
tttcgttagc tcagctggtt gtatcttatt atgttctgac tgttttgtag ttcctttgtt 20160
cctttcttcc tcttgatatc atttttttta attgataatt ttccttagtg gtatagtttt 20220
tttaaagtat ttttagtgcc ttatttgagg taaaattgtc atgcagtaaa ctgcacaata 20280
tttaaagtat aatttgatga atttaacata tatatataca catacacatc ctgaaactat 20340
cacggcaatc aagataatat acatatctat tacctccaaa aaataaaaca gacccatcta 20400
atcagcctcc agtgtaaagt gaagagctgt attttaacaa ttttgtttgt ttgtttttat 20460
taattggaga gtaatttctt tacagtgttg tgttggtttc tgccataaaa caatgtgaat 20520
cagccataag tatacatagg ctccctctgt cttgagcttc cctcccagcc gccatcccac 20580
ccctctaggt tgccacagag cactgctgag ctccccgtgg tatcagcaac gtcccgctag 20640
ctcctgtcta cacgtggtaa tgtgcatgtg tcagtgctgc tctctcagtt tggcccccct 20700
ccttccgcct ctgtgtccac agtctgttct ctctgcgtct attgctgccc tgctaatagg 20760
ttcatcagca ccatttttcc agattctgtg tatatgcatt gttatacaat acttgttttt 20820
ctctttctga cttacttcac tctttataac agggtctagg ttcatccacc tcactgaaac 20880
tgactcagat ttattccttt ttgtttattt tgttcctttt tacggctgag taatattcca 20940
ttgtatatat gtatcacaac ttccttatcc attcattttt cagtggacat ctaggttgct 21000
tctgtgttct ggctgttgta aatagtgctg cactgagcat tggtgtacat atgtcttttt 21060
cagttatggt tttctcagga tatatgccta ggagtggggt tactgggtcc tatggtagtt 21120
ttatttttat tcttttttct taaataaatc tccacactgt tctccctagt ggctatgtcc 21180
gtttacattc gtaccaactg tccaagagcg ctcccttttc tctgcatcct ttcctgcatt 21240
tattgtttat agattttttg ataatggcca ttcttactgc tgctgctgct gctaagtcac 21300
ttcagtcgtg tccgactctg tgtgactcca tagacctcag cccaccaggc tcttctgccc 21360
ctgggattct ccaggcaaga acactggagt gggttgccat ttccttctcc aatgcatgaa 21420
agtgaaaagt gaaagtgaag tcactcagtc gtgtctgact cttagcgacc ccatggactg 21480
cagcccacca ggctcctccg tctgtgggat tttccaggca agagcactgg agtgggtgcc 21540
atcgccttct ccgaggccat tcttactagt gtgaggtgat acctcattgt agttttgatt 21600
tgcatttctc taataatgag tggtgttgaa cattttttca tgtgtttgat ggccttctgt 21660
atgtcttctt tggagaaatg tctgtttagg tcttctgccc atgttttaat tgggtttgtt 21720
tttcaaatat tgagctgcct gaactgcttg tatattttgg agaatcctta gtggcatgtt 21780
ttgatcttga tcttttatct gtctgttcta gttttctgtt ttgtgatttt tgtgagggtt 21840
ataaaaaaca ccttacagta ataagaatca attttaagct aataacttaa ctttgatagc 21900
atataaaaat tccgtgcttt tctctcttct tccactttat gtttttgata gcacactttt 21960
tacatctttt tatattgtaa aattattgta gctatagtga ctttaatact tctgtgcctt 22020
atcctttata ctagagttaa gagataacat accagcataa tacagtacta aagtcatcct 22080
cagtatgtgg gagattggtt ccatgacacc ccccatccct tgtgtatacc cagaatccat 22140
ggatgcctaa gtcccttgga taaaatggag tagtgcttac atataacctg taagtcattt 22200
gtagattact tataatacct aatgtagtgt aaatatcatg tacgtagttg taaatgctgt 22260
gtacattgta gctggagtag tgcatattca aggtttactt tttggaactt tctgagactt 22320
tttttcctca gatattttca gtcagtttct ttcagtctgt gaatgtggag ttcttgaata 22380
gggagggcca actgtatttt gaatttgact gtgtacttgc ctttaccagt gtgttttata 22440
tttccttatg ttttcctgtt agtaatgtcc tctcatttca gctggaagaa gtccttttag 22500
catttcttgt aaggcagatg tagtgatgat gaatgctcta cacatttgtc tgactgggaa 22560
aatctttttt tttttttaat ttatatattt cttttttgct gcactggact ctttgctatg 22620
agcaagcccc ctggttgtgg ccagtggggt gcggcactag ctgtgctggg gtctcgtggc 22680
tgtggcttct cttgttgcag agcctgggct ccagggcaca tggctccagt agttgtggcc 22740
gtgggcttag tcgccctgtg gatgtgggat cttagattct ggacgaagga tcgaacccat 22800
gtcccctgca ttggcaggtg gatttttaac cacaggacta ccaagaagtt tcctgtgtgg 22860
gagaatcttt atctcgcctt catttctgaa gggtaggttt gccaggtaaa gtattcttgg 22920
ttggcagatt tttttgcttt gttttgtttt attgaaatat ggttggttta cagtgtggtg 22980
ttagttgcag gtgtacagca aaatgattca atgtttttta tgtatctgtt ctttttaatt 23040
gttttcccat ttaggttgtt tcataatatt gagcagagtt ccctttgcta tacagtaggt 23100
ccttgttggt tatccttttt cagtataaca gtgtgtacat gtcagtccca agctccctaa 23160
ctgtccctcc cacagcctgt cccctctagt agccataagt ttgttctctg agcctgtgag 23220
tctatttctg ttttgtaaat atgttcactt gtataatttt tcaaagattc tgcatataaa 23280
tgatatcata ccatatttct cttgctctga cttacttcac ttaatatgac aatctctagg 23340
tccatccttg ttgctgcaaa tggcattatt tcatcctttt taatggctga gtgatattcc 23400
attgtaaata tgtaccatat cttctttatc cattcttctt ttgatgaaca tttaggttgc 23460
ttccatgtct tggctattgt aaacagtact gaaaagaaca tggggagtgc atgtatcttt 23520
tcagaccagg ttttccctgg atacatgccc aggagtggga ttgcaggatc ttacagtagt 23580
tctatttgta gtttctttag gaatctccat acttcttttt tccatagtgg ctgcttcatt 23640
ttgtattccc accaacagtg taggagggtt cccttctctc caccccatct ccagcattta 23700
ttgtttgtgg attttgatga tagccatttt gactggtgtg aagtgatatc cattttagtt 23760
ttgatttgca tttctgtaat aattagcaat gttgaacatc tcttcatgtg cctcttggcc 23820
ctctgtaagt cttctctgga gaaatgtttg tttaggtctt ctgcttattt tttgattggg 23880
ttgtttcttt tgatgatact aagccacatg agctgtttgt aaattttgga tactaatccc 23940
ttgttggtca cattactggc aaatattttc tcccattatg tgagttgttt ttaattttgt 24000
ttatggtttc ctttgctgtg caaaatttga gcctaattag gtctcatttg tttatatttg 24060
tttttatttc cattactctg ggagacagat caaaaagata ttgctgagat ttctgttgtg 24120
agtgttctgc ctgtgttttt ctctgagttt tatagttttc agtgtcacat ttagatcttt 24180
tatccatttt gaattttttt tgtgtgtata gtgttaatgt tttaatttta tctttttgca 24240
tgtgagttgt ccagttttcc aagcactgtt tggactgtct ctcctccgtt gtatagtctt 24300
gcctcctttg tttagattaa caatggccat gggtacatgg gtttatttct gggctttctg 24360
tcctcttcct ttgatccgtc tttgtttttg tgcccatacc atattgtttg gataatataa 24420
ctttgtagtg tggtctgaag aaagggggcc ttttcttcca gctccatttt tctttgtcaa 24480
gattgctttg gctatttggg atattttgtg tctccacaca aattttaaga tattttgttt 24540
tagttctatt aacagtgcca ttggtaattt gatagggatt gcactgaatc tacagattgc 24600
ctttggtagt atgtcatttt aacagtattg attattccag tccaagaaca tgatgtatct 24660
ttccatctgt ttgtgtcatc tctagtttct ttcatcagtg tcataatttt cagagcacag 24720
gtcttttgtc tccttattcc taggtacaat attttattct ttttgatatg atggtaaatg 24780
gagttgtttc ttgaacttct ctttctgatc tttcattgtt agtgtataga aattcaacag 24840
atttctatgt tttaattttg taacctgtaa ctttaccaaa ttcattaatg agctttagta 24900
gtgctgttag agtttcctgt gtatagtatt atgtcatctg aaatagtgac acttttaact 24960
ggttctttcc cttttcctat ttggatacct tttatttctt ttgtcttttc tgattgccat 25020
ggctaggact tccaaaaact ctgttgaata aaagtgacga gagtgggtat tcttgtcttg 25080
ttcctgatct tagaggaaat gctttcagcg cttcaccatt tagtatgatg ttagctgtag 25140
atttgtcata agtggacttt attatgttga ggtaggttcc ctctgtgccc attttctggg 25200
gagtttttat tgtaaatgga tgttgtattt tgtcaaaagt tttctttaca tctattgaga 25260
tgatcatata gtttttagtc ttcaatttgt tgatgtggtg tatcacactg atttatggat 25320
attgaaaaac ccttgcatcc ctgggaaaaa ttccacttgc tcatgatgta tgatcttttt 25380
aatgtattgt tggatttgga ctgctagaat tttgttgggg atttctgtgt ctgttcttta 25440
gtgatcttgg cctgttattc tgtgtgtgtg tggtatgttt gtctggtttt ggtatcaggg 25500
tgatggttgg cctcacagaa tgagtttggg gagatttcct tcctctgcag ttttttgcaa 25560
cagtttcaga aagataagtg ttagctcttc tctaaatgtt tgacagaatt cgcctgtgta 25620
gccatctggt tctggacttc tgtttgttga gagttttggt tttttttttt ttaaggtaga 25680
cacgtttctt tttctttctc tctgtctttt ttttttaaca gtaatttttt aaaaaacggt 25740
agccattatt cttttttctg actgcactgg gtctttgttg ctgcacgtgg ggtttctcta 25800
gttgtagaga gcgagggctc ctttctagtt gtggtgagtg ggcttctcgt tgtgttacat 25860
tgtggtggct tctcttgttg cagagcgcag gctctcaggc gtgcaggctc agtagctgtg 25920
gagcacaggc ttagttgccc cacagcatgt ggaatcttcc tggaccaggg atggaacctg 25980
tgtcccctgc attgacgggc gaattcttaa ccactggacc accagggaag tcctgttggg 26040
agtgttttaa tcacagtttt aatttcagta cttgtgattg gtctgttcat attttctgtt 26100
tcttcctgtt tcagtcttag gaaattatac ctaagaattt ctccatttct tccaagttgt 26160
ccttttcatt ggtgtacggt tgctataata gtctattttt aaaatatata tattatgaaa 26220
gtatagttgc cttacaatgt tttaggtaca cagcaaagtg attcagttac atatatattc 26280
atatattatt tttcagatta ttttccatta taggttatta aagatattaa ctatagttcc 26340
cagtgctata tggtgaactt ttgtttattg ttgcatatct atttttttaa attagaaatc 26400
tagcattcta ttcatactgg gtcaaacaag tggaatcaaa atgtcataaa ttttttaatt 26460
agacaaaaat tcattagttt tctaaaatac atattataca tgctatatat atatgtgtgt 26520
atatactacg cttgataaag gcttgagaaa gaacttaaaa aaagagaagg gatggagaaa 26580
ttagaaaaca taaaggaaat ggaagccctg aatatgaaat agaaaaagtg gaacaaacta 26640
gataaaagtg aaagatcgtc atatagtcca gttgttttga agcatggctg ctcattagaa 26700
acatttctgg agctttggag gaaagaagca atacctggac atttatattt ttcaaaaatg 26760
taattgtctc ttacgattct ttgtatttct gtgctgtcag ttgtaacttc cttttcattt 26820
ctgattttga tttgagtcat ttcccttttt tcttgaagag tctgtctaaa ggtttatcag 26880
ttttgttatc ttttcaaaga atcagctttt agtttcattg acctttcgta ttgttttctt 26940
catctatatc tttattttat taatttttat tggagtatcg ttgctttatg tcatttattt 27000
ctgctctgac ctttatgatt tctttccttc tactaacttt aggttttgtt ctttctctgt 27060
ttgcttttgg tgtaagttta gattgtttat ttaagattat tttttcctga aatacggttg 27120
tgttgctatg aaatgctctc ttggatttgc tctggttgta ccctgtaggt ttgggatcac 27180
gtgcttttgt tctcattcat cactaggtgt cttttgaatc ctctttgagc tcttctgtgc 27240
ccactgcttg tgtagcagcg tgttgtcttc tatgtgtttg tgttttttat agtttttttt 27300
tccttgtagt gtatttctaa tctcatagcg ttgtggttgg aaaagatgct tgatataatt 27360
ccaactttct taaatttacc aagacctgct ttgtgatcct gtttttgttt tgttaataag 27420
atggtttgta ttatttttta gatttcacat ttaagtggta taatataaca cttgtctttg 27480
tcttcacttg gtgtgatgta ctctaggtcc gtccatgttg ctgcaaatgg cagtatttct 27540
ttttttaatg gctgagaaat attccattga atgcatgtgt gtgggtatgt gtgtatcaca 27600
taaagaacac atattcttca tgcattcatc ttttgagggg tacttatctg ttgtacatag 27660
tactgctgag aacattaggg tgcatctgtc ttttcaaatt agagttttca gcttttctgg 27720
atataagttg gcagatttct ttcctttttt tttttgcagc attttgaata attcatttca 27780
ttctctcttg gcctgcaata tgtgaggaat ccactggtag ccttatggga gtttccttgt 27840
atgtgagcaa tttttttctc tagttgcttt taaaattctc tttgtctttg attttaggtg 27900
atttcattat ggtgtgtctc gagatctttt gggggacctg taaaaacttg gatgtctaaa 27960
tctcttcaca gattgggaag atctcagcta ttatttcttt aaataagttt tctgcccctt 28020
tctccctctc tcttcctttg gggattccaa caatgcttag gttgtttctc ttcatacccc 28080
ataatttgtg aaggctttct tcactttttc atattttctc ttcattcacc ttaacctgga 28140
taatttcaaa ttacctgtca ttgacttaat ggattttttt tcttctgctt gattaggtct 28200
gttattaata cttcctagtg cattttcatg gagaaggcaa tggcacccca ctccagtact 28260
cttgcctgga aaatcccatg gacggagggg cctggtgggc tgcagtccat ggggtcgcta 28320
ggagttggac acaactgagt gacttcactt tcacttttca ctttcatgca ttggagaagg 28380
aaatggcaac ccattccagt gttcttgcct ggagaatccc agggacgggg gagcctggtg 28440
ggctgccgtc tatggggtcg cacagagtcg gccacgactg aagcgactta gcagcagcag 28500
cagtgcattt tcatttcatt cattttagtt ttcagcacca tgatttgtgt ttggttcttt 28560
ttatgattta tgtctctctg ttaaattttt ccttttgttc atgtgacttc cctggtggct 28620
cagatggtaa agaactcacc tgcaatacaa tagacctggg ttctgtccct gggtcaggag 28680
gatcccctgg agaagaaaat ggcaacccac tctagtattc ttgcctggga aatcccacag 28740
acagaggagc ctggcgggct acagtccctg gggtcgcaaa gagtcggaca caactgagtg 28800
accaacactt ttgttcgtgt attatttttc tgacttcatt gaattgtctg ttttcttgaa 28860
gctcattaag gatatcttta aaacaaatat tttgaatttt ctgttgggta cattgcagat 28920
ctccatttct ttggggtcag taattgaaga attactgtgt tcctttggtg tcatgtttca 28980
tggagttttc gtattccgtg aagtctcata ttgctgtctt tgcacttgaa gccatcatct 29040
cttccgggct tcaggagaga tacaactcct atcagacctg ctagggattt ctcagtaaat 29100
gaaaatgtca ttagcagtta ctccaaatgc ttttttaatg gttattaagt tttagaatca 29160
acctgtagaa aacatatgga agattttgta agagttgaga aagtgaatat tacatatctt 29220
gatgatctat gaagataata agcattaaaa taactaaaat tggaactgcc ttccagtact 29280
tttgatagaa gtccatgtat accacttctg taattgaaaa gtaatcgcca ttgcaactca 29340
taaaaggtca cttgggggtg atactctcat tcttgatcga gtgatattta gatcagatgg 29400
ctgtgtttac tttcatggag ctatgtgctt ataatctgtg tgcttttctg taatatttta 29460
tgctaaactt taaaagttta cttaatgttg actcaatagt cattataaaa aggttacaag 29520
tacagagagt tgacttaaat tgcctctgca tgtaagaata tcacatggag aaaaacaacc 29580
actgttacca acatttcttt ccattctctt gttgtgcctt tttttgacca cgtggcgtgt 29640
ggaacttccc caagccaggg atagaaccca tgaccctgca ttggaagtgc agagtcttct 29700
gaccactgga ccaccaggga agtcctgttg tgcatctttt gcctatatcc tttacttaat 29760
tttttttctg attggaaaag tacatgttct ctttagaaaa gttactaaac acagaaaggc 29820
catgcttctc acaatggaat aatgatatga ttgacaaaat gatgccaagg accatagtat 29880
ggaaagtttc attaatggca aagaacccgg aaatttaaga tgtttatgtt aaaagtgtaa 29940
gggctctggg attttcctgg cagttcagtg gttaacactc catgctaccc atggagggtg 30000
cacgggttcg atccctggtt gggaattaag tctgcatggc atggccttaa aacaagtgaa 30060
aatgtaagag tcctgatttt cctcagcatg tagtaagcac acagtaccct gtgcctctgg 30120
ctgcatgtgt gctaaggagc ttcactgtgt ccgaaactgt gcgaccctat ggactgtagc 30180
cagtcaagct cctctgtctg tgagattctc caagcaagaa tactggagtg tgttgctgtg 30240
ccctcctgta ggggatcttc ccagcccagg gatcaaaccc aggtctcccg cattatagac 30300
ggattcttta ccatctgagc caccagggaa gcccaaaaaa ctagagtggg tagccgcctg 30360
tcccttctcc aagcaaactt cccgacccag gaattgaacc agggtctcct gtgttgcagg 30420
caaattcttt acctgctgag ctaccagggg agcccgttct ctatgtatct cttacatctc 30480
ctgcattggc aggcaggttc tttaccacta gcgtcacctg ggaagtcctg gctgattaca 30540
attaaatgac tagggccgat ggcatggacc agcgattgga aaggaaactg attttgtttt 30600
ttctctccat agagtatctt ctagcatgga ctcaaaagta acccagaacc tggaactgga 30660
cactaggttt agacagaagt ccaagagaag cctgtctttc tagtctgagg agtgagaaag 30720
ggagattaga ggatagggat gcaggaagaa aatcttgtgt cttgtttatt tgtttttctc 30780
ccctccattt tctcctgctc ttgttcccca tgaaattttg tggtggtgaa ggcaataatg 30840
acattggcag ccagcaggga gaggaatcct tttatttaca gggattatgg tctcaagagc 30900
atggagaaat ttgcggattt tgttctcaat tcttactgct tgacctggga agcaatcaca 30960
gttgtgggag gtgctcagca gtagaaagaa atgaaattct ttcctttctt gccagtagac 31020
ccgcaaaagg tcctctggga gctggaatgt cttggaaagg ttgtaaagag gaacgtgaaa 31080
gtcgctcagt catgtccgac tctttgtgac cccatggact ggagtgggta gcctttccct 31140
tttccagggg atcttctcaa cccaggaatc aaacccaggt ctccctcatt gcaggcagat 31200
tctttaccag ctgagccaca agggaagtcc aagaatactg gagtgggtaa cgtatccctt 31260
ctccagcgga tcttccggac ccaggaagcg aaccggggtc ttctgcattg caggcaattc 31320
tttaccagct gagctgtcag ggaagccctg gaaagaggaa ggaactcaac aaagtgaacc 31380
cgtaacactg tgtatgaact cctgggttct cctaaatatt atctgtgcat ttgatcctaa 31440
acagcacacc agaggctaga ctgctgccca agtcatgtgc cggaatctgc acagtatgct 31500
tgagacaagt cagaatgata ccacaggggc tttgaaatga tctgatgttg gaaccacagc 31560
ccagggagag tggaaaggaa tttgtggatt ggacctaatc agggagatta ctgctaaaac 31620
aaaaatatgc acttgcttca gcagcacata tactgaaatt ggaacaatac agagaagatt 31680
agcatggccc ctgtgcaagg atgacacgca agttcctgaa gtgtttccta ttttttttcc 31740
ttaaaaaaac taggaataga actaccatat gacccgacaa tcccactcct gggcgtatac 31800
cctgagaaat ccataattga aagagacgca tgaagcccag tgattgctgc agcactgctg 31860
acaatagcta ggaagcacct gtgtccaccg acagatgagt gaagaaggac gctgtggtgc 31920
ttgtgtgcaa tggaatgtta ctcagccata aaaaaaacac atttgagtca gtcttaatca 31980
agtggatgca cctgaaacct gttatacata gtgagatggg tcagagagag aaggacaaat 32040
accatatatc aatgcatatg tatggaatct aggaagatgg tactgatgaa cctatttgca 32100
gggcagcagt ggatacacag acatagagaa caggctttcg tggacccagt gggggaagga 32160
gagggtggga cgaattgaga gagcaggatg gaagcatata cattgcaata tgtaaaatag 32220
ttagctagtg gaaatttgct gtatgaggta gggagctcaa atcagggact ccgtaacaac 32280
ctggaggggt gggttggggt gggaggtggg aggaggttta agagggaggg ggcgtatgta 32340
tacctccggc tgattcatat tgataatggc agaaaccaac acaatattgt aaagcaaata 32400
tcgtccaatt aaaaactaaa aagaaaaaag cccaccattt tctattggac ttgaacaaga 32460
tccaggataa cgtagcatag tatccaaaca ttcaaaatta ctcaggaaaa tcttaccatc 32520
tcctaagggg caaagatagt cagcagatgg ccatcatgac ataacaaaga tgttggaatc 32580
acaaaggatt taaactataa ttattagtta aaacctggct gtaatacttg agggtgcaca 32640
ttcttttttt tttttaagtt tgtttctgtt tggccgtgct gtgtctttgt tgccgcgtgg 32700
gcttttctct agttgtggcg ggggaggctg ctcgctggtt gcggtgcaca ggattctcgc 32760
ggccgtggct tgccttgcag agagcacagg gtctgtagcg cgcggttgca gggttgcggc 32820
tcccacgctc cagagcacag actccacagt tgcggcacat gggcttagtt gctccgcagc 32880
tttggggatc ttactggacc aggggtcgaa cctgtgtctc ctgcattggc aggcagattc 32940
tttacccctg gactaccacg ttattcctcg agggtgaaca tttctgaaac aaatggaaag 33000
atagacactt aaattggaag ttttataagt gaaactatat ttaaaattca ttgagtggac 33060
tcagtgacag aatagagata tattaagaag tcagttaacc tgaaagtaga agggcaaaac 33120
gtatgtattt gaacaacaga tttttaaaat aaactgaaga aaaatgaagg gatcttcagg 33180
gcccatggga aaataacaaa acgtttatct ttcatgttat cgaagtctca gaaggagtgg 33240
agatggagtg cagtaaaagt gtgtgtggac attataggaa gaaagaaaga tgtttcttat 33300
gcagttgaca tgatattcta cttagaaaat cccaaggaat gtacaaaaaa gactggagct 33360
aattattgag ttcagcacaa atgcaggata caagagcaac atattgaaat cagttatttc 33420
tttgtatgag cgattaacac ggggaaactg aaattgaaaa cagaaccagt caaaaaaaat 33480
tgggtgtaaa tctaacaaaa catgtatagc acttgtacgc taaaaacagt aatgattaaa 33540
gtaatacagt aatgattaaa gagggagttc atgtgaatgg ttaagactct gcttccattg 33600
caggggacat gagttcagtc tctggtcagg gaactaagat cccataagct gcagtgctgc 33660
caaggggaaa aaatcaaaga ttaaatagag atatttcgtt cataggttgg aagactaaac 33720
atagcagcaa tatcatttct tctcaaaatt gataatgcaa gtttattgta attcctatca 33780
aaattctagc aagatttttt ttagacatag acaagattac tctaatatct atatggaaag 33840
gcaaagaaac taggaaaggt aaaacaattt tgaagaagaa tagaatgaga ggactctctc 33900
tacccatttc aagactttag agctacagtc atcaagacca cgtggtgctg ggggagggac 33960
agacgcacag atcagtgcaa cagtttagaa aacctagaaa tagactcaca caagtacagc 34020
cagttgcttt ttgactgaat gtttgtgtgc cccgcaggtt cttatgttga aaccctcagt 34080
gtgattatat caggaagtca tagcctttgg ggggataatt acgtcatgag ggtggagtcc 34140
tcatgaatgg gaatcagccc cataaatgag gctgcagaga gctctcactg ccttttgtgc 34200
caggtgaagg cggtgagcag atggccacca gtgaaccagg agatgggccc tcagcagcag 34260
ctgagcccgc cagtgcctcg gcctggactc ctagactccg gaagtgtgaa gagtaaatat 34320
ttattgttta agccacccag tgtatgctat ttttgctgta acagcccaga gggctaagac 34380
aggtgccaaa gcaattcagt ggaggaaagg tagtcttttt aacattcagt gttgcaacaa 34440
ttggttatcc acagggaaaa acaaaatgca aacctaacct cacatcttac acaaaaaagt 34500
gactcaaatg tttcatagat ttaaggtggg ctcagacagt aaacagagaa ggtaatgtca 34560
ccccactcta gtactcttgc ctggaaaatc ccatggagag cctgcagtcc atggggtcac 34620
taagagtcgg acacgactga gtgacttcac tttcactttt cactttcatg cattggagaa 34680
ggaaatggca acctgctcca gtgttcttgc ctggagaatc ccagggatgg tggagcctca 34740
tgggctgccg tctatggggt cgcacagagt cggacacgac tgaagcgact tagcagcagc 34800
agcaatactc cattatgtat atgtaccaca gctttcttat ccattagtct gccaatggac 34860
atctaggttg cttccatgtc ctggctattg taaacagtgc tgtgatgaac attggggtac 34920
acgtgtctct ttcaattctt gtttcctcag tgtgtatgcg cagcagtggg attgctaggt 34980
cataaggcag ttctatttcc agttttttaa ggaatctcca cactgttctc tatagtggct 35040
gtactagttt gcattcccac caacagtgta agagggttcc tttttctcca caccctctcc 35100
agcatttatt ttttgtagac tttttgatag cagccattct gatggcatga gatggtacct 35160
catggtggtt ttgattttgc atttctctga taatgaatga tgctgaacat cttttcatgt 35220
gtttgtaagc catctatatg tcatctttnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 35280
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 35340
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 35400
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 35460
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 35520
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnngagattc cagttgggct 35580
agaggctgag cacctttggg aacaacgttt aagggaatgt gagcacaatg caaagtgtct 35640
ttaaaagcat gttgtgatgt acacattttg taattacctt ttttgttgtt gatgtaacag 35700
ccatttgtaa aaaaacattc cagataattc cgtagttctg aagcagcagt ctaatccctt 35760
tctcactttt ggaaggtaac atttcagctt aatgcatatt gccttctcca gagagaaagg 35820
gaaaaggttt gggcctgcct tactgagagc ctagcagccc agagaaaggc tccatttggg 35880
gaaaccccat tgccctgtaa aaagtacctg ccaaaccaga aagatgattc cgggaggagt 35940
taaccaaaaa aaaaaaaaaa atgctgttca ggttttcagc tttacggtat ctttggaaaa 36000
cctttttttt ttttcttttt tcatcagaag tgaccaaaca attaagatgg tgaaacctga 36060
gaccaaatcc ttgtcccagc tctaccctgt tcccaactgc tcacagaatg gatcatgtgc 36120
cccttatatt gaagtgacca cttatttgtt ctcctgcctc cttgaaagaa aggaaagaaa 36180
attatgtttt gccactgatt tagccatatg aaactcatct catcaccctt ttctgggtct 36240
gaagctgctg tctctaaaag tgccatctca ccgtgctttg tatcggttag tgctggagaa 36300
atcttgaaaa gcgtatgtac aaaacttgta aatttttata ttttggaacg ttgcttcttt 36360
ggggttgagg cacactggtc acccctctgc ctgtgagagc tctctacagt ctgtgggcta 36420
gcagtgtgct gatcttttaa agtttctttc cctacccaat cccccttttt tgatgaggtt 36480
tcagtgaggt ctgttagggg tgcatcctgc agcttaattg gcttaaaatg ttctctcctt 36540
tggtgtggtc tctttgggga ccaactggga gaaaaaaaaa ccaatagtgt aacggctttg 36600
atactgaaaa ttgataaatg tctttttgaa ataaagaacc agtcccgcca aaataaataa 36660
ataaatcaaa aaaaaaaaat taaaagcttt ggctctatca tagagtctgt gaaaagaatt 36720
ttaagaagac aggttacaga tttgaagaca atatttgtga acaacatatc tggcagggac 36780
ttacatctag aataactaga atatattata taaggagatc tcagcaactc ctaaatacct 36840
agtggatcaa agaagaaagt acgtgaggag ttagaaaata cttttgagat gaatgaaaac 36900
caaacaaaaa ttcacaaata cagaagctgt gggatacaac taaagttgtg tttagaggga 36960
aatttacaac tgttagtgcc tgtattaaaa aacaaaaaac agatcagtaa ccttaagaaa 37020
ctagagaaag aagaaaaaga agaagctaga aaagataaaa ataaacccaa aacaaagaga 37080
aggaagaaaa taataaagac tagagtgtaa acaaatgcag agaaactagg aaaatagtga 37140
agtacataaa agcaagagtt tgttttatta aaagatcaac agagaataag aggaagctca 37200
aataactgga atcattacag aaagtgggaa cgggacagta ccaccaacct tcagtaataa 37260
aaatgactat aatactatga acggcaaata ttatgctaat aaataagata gcctaggtga 37320
aatggacaaa tttctggaaa cacacaaact aacaaaattt attcaagaag aaatagaaaa 37380
tctgaataga cttgacagat aaagagattg agttaatagt ttaaaaactt cccacacaga 37440
aggaaaaagc ccaagatcag atggcttcac tagtaaattc tgtcaaatct ttaaagaaga 37500
tttaactagt attgactgga cagacttttg ttggtaaagt agtctctgtt ttttaatatg 37560
ctgtctaggt tggtcatagc ttttcttcca aggaacaagt gtcttaattt catggctgca 37620
gtcacaatct gcagtgattt tggaggcccc caaaataaag tctcttcact gtttccattg 37680
tttccccatc tattgaccat gaagtgatgg cactggatgc catgatatta attttctgaa 37740
tgttgagttt taagccaact ttttcactct cctctttcac tttcgtcaag aggctcttta 37800
gttcctctag gctcttcact ttctgccata agtgtggtgt catttgccca tctgtatctg 37860
aggttattga tatttctccc agaaatcttg attccagctt gtgcttcatc cagcctggca 37920
tttcgcatga tgttgatgta ttctgcatat aagttaaata agcagggtga caatatacag 37980
ccttgatgca ctcctttccc gatttggaac cagtctgttg ttccatgtcc agctctaact 38040
gtctcttctt gacctgcata cagatttctc aggagtcagg taaggtggtc tggtattccc 38100
atctcctgaa gaattttcca cagttcactg tgatccacac aaaggctttg gtgtagtcag 38160
taaagcagaa gtagatgttt ttctggaact ctcttgcttt ttcgatgatc tagtagtgaa 38220
tgttggcaat ttgatctctg gttcctctgc cttttctaaa tccagctgga acatctggaa 38280
gttcacagat aatgtactgt taagcctggc ttggaaaatt ttgagtatta ctttactagc 38340
atgtgagatg agtgcaattg tgcagtagct tgagcattct ttggcattgc ctttctttgg 38400
gattagaatg aaaactgacc ttttccagtc ctgtggccac tgctgagttt tccaaatttg 38460
ctggcatatt gagtgcagca cttgcacagc atcatctttt aggatttgaa atagctcaac 38520
tggaattcca tcgcctccac tagctttgtt catagtgatg cttcctaagc cccacttgac 38580
ttcacattcc aggatgtctg gctctaggtg agtgatcata ccatcgtgac tatctgggtc 38640
atgaagatct tttttgtaca gttctgtgta ttcttgccat ctcttcttaa tatcttttgc 38700
ttctgttagg tccacaccat ttctgtcctt tattgtgccc ttcttcgcat gaaatgttcc 38760
ctttgtgtct ttaattttct tgacgagacc tctagttttt cccattctgt tgttttcctc 38820
tatttctttg tattgatcac tgaagaaagc tttcttatct ctccttgcta ttctttgaaa 38880
ctctgcattc aaatgggtgt atctttcttt ttctcgtttt cctctcacta gccattaggg 38940
aaatgcaaat caagatcaaa taagatactt atacactcct attaatcctg ctaaaataaa 39000
gaatagtagc aataccaaat gctggtaagg atgccaggaa acgaagtcgc gtctggtgga 39060
agtgtaaaac ggtgtgggta ctctggaaaa tacgttggca gtcttaggtt gtatagtaca 39120
ttttatgttt cctagcagtt tcacttctgg gtatttattc cagagaaagg agatagtaaa 39180
tatttgtggt aagaataagc atgatgggtc cagtatggct gaaatttagg ggagatggta 39240
aggcttttca acaaatgatc ttggaaagct ttgagacaga gcctgcagtc tatgtcgttt 39300
tttgcatctc ttttcctact ctctccttga ggtttgacac atttattttt cttggttgag 39360
tgtttaactt gtgtgagttg gttgaagaga attttaaatg ctgaaagttt ggtgaatata 39420
ggcacaaaat agaccatcat ctctttaaaa aaaaaaaaat gttctatgtt aatgtatgtt 39480
aacgtgtatg gatttttcta aaacttgcgc atctgtgatc tgatttgggg ctggttcaga 39540
atcacaggtt cggcaagctc gtgacacagt ggcacctgtc tgcctcccca gcctgccctc 39600
agggactcct cctgttcttt gtgccctttg tcctctgagc cagtgggtct gacttgatct 39660
gggcttgtcc tcactgtaga cttcctccag ggctgttctt tgtcctggtt ccaatagttt 39720
tttttcttga tacatacagc tctatgctgc tgctgctgct aagtcgcttc agtcgtgtcc 39780
aactctgtgc gaccccagag atggcagccc accaggcttc cccgtccctg ggattctcca 39840
ggcaagaaca ctggagtggg ttgctgtttc cttctccaat gcatgaaagt gaaaagtgaa 39900
agtgaagtca ctcagtcctg tccgactctt cacgacccca tggactgcag tctaccaggc 39960
tcctccgtct gtgggatttt tccaggcaag agtactggag tggggtgcca ttgccttctc 40020
cgatacagct ctataatttt ggtctataac aacagagccc tttgtttttg cttgtagcag 40080
ggtctcccat gaaggcattg gacaaaatca tttacatttt tgtgtaatag gtccactcag 40140
gcccctaggg cctccatccc ttctacatat tgtgtctatt tttaattttt aaaaattatt 40200
tcaagtcact attttttatt tttttaaatt atgtttttaa ttttttaaat tatttttatt 40260
gtgttaaaat atgtataaac ataaaatttg ccatgttaac tatttttaat tgtgcagttc 40320
agggacatta attacatcca cagtgttgtg cagccatcac cattatctat ttcgaaaact 40380
tttcatcaac ccagaaagaa gctgtaatta gtaactccct atcctctctg tccccaggct 40440
cctagtaacc tctaatctgt cttctgtctc tatgaatttt cctaatctag atgtttctta 40500
taagtggcat cacataaagt ttgtcttgtt gcatctgcct tatttcattt agcatgtttg 40560
cagggtctat ccatgttgta gtgtatatca gaacctcatt cctttctgtg gccaaataac 40620
attccactgt atgtgtacat atcacgtaaa aactgttgtg tctctttaaa ttcgggaagc 40680
tgagttcaga gtgtagattt tgagctgaag aaatttataa gtgtggggca atgtaggaaa 40740
gagaaaattt cagttcaggt tggataaatt gggctttgaa atagctttgt gtcaaagtga 40800
acatagtgga ggaaagataa gttaattctc ttgccaggtc caggtaggtg ggctgtgtaa 40860
ggaactagaa tttggacttc tttttttgtt tgtttcatga ttttgttttc cgggtgctat 40920
gaaaatgaac aattcagttc agttcagtca ctcagttgtg tctgactctt tgcgacccca 40980
tgaattgcag cactccaggc ctccctgtcc atcaccaact cccggagttc actcagactc 41040
aggtccaccg agttggtgat gccatccagc catcttatcc tctgtcatcc ccttttcctc 41100
ctgcccccaa tccctcccag catcagagtc ttttccaatg agtcaactct tccatgaggt 41160
ggccaaagta ctggagtttc agcttcagca tcattccttc caaagaaatc ccagggctga 41220
tctccttcag aatggactgg ttggatctcc ttgcagtcca agggactctc aagagtcttc 41280
tccaacacca cagttcaaaa gcatcaattc tttggcactc agctttcttc acagtccaac 41340
tctcacatcc atacatgacc actggaaaaa ccatagcctt gactagacga acctttattg 41400
gcaaagtaat gtctctgctt ttgaatatgc tatctaggtt ggtcataact ttacttcata 41460
ataaagatga atgggaaatg aaaatgacta agatcatgtc agaaaagact tggacttggt 41520
gcagaatgaa gggagatgtt tttgtttttg tttcctcata ttagtaattt catgtataag 41580
ataacagaag aggcctgaga agaagattag gattagtagg atcacagttt cctggtggac 41640
ttggtttggg gacctttagg ggaagagacg tggggcttgg cagaggactg aggttggaaa 41700
agctccagct tgttcctgac agtgtctttc cacagacagg cttctcatta gtgttcgttt 41760
cccccttggg gcaggatgga gggttagggg cgtgggagca gaaaggtcac ttccccagag 41820
tcctgggtta tgctggtggg gagcgcggct gcagggtcgt tctgtgggcc ctggcctgag 41880
accttcgtga gctctggggc tgcaggtgag cctgggaact ggctgggctc ttgtcagcag 41940
ctctgctact tgggcagagc tgtcacttgc tggctcccct gcctgctgcc ttttgagttg 42000
acccacagag gctcggtgtc gtgtttgctt agaaggttct tggactggag gattgcacgc 42060
atgcttgcca cttgtgcctc caggaaggct gatggagtga atcccttctt gttaaccggc 42120
tgtggtgtga ctgctctcgc ttctcttttc tggtctcaca cttctgaggc atcacctctt 42180
tggcctgggt ttcatcagtg agccagatca cgctgagaca cacgtctggg caggttctgt 42240
gtagcacaga ctggaaaaga gcaacacgga acagaagtag attttttttt tttttttttt 42300
taagaaatat ggttttattt ttatttgtta atgtaatggc tgtgctgggt ctttattgct 42360
ctatgctggc ttttttcttg ttgcagcagg tagggggctg ctgtctagtc gtgccgtgtg 42420
gtctctcctt gccgcggctt ctgctgtgga gcacgggctg tcggtgcacg cgccttcagc 42480
agttgcggct catgggcttt agtacaatgc tctcagtggt tgtggcccgc gggcttcatt 42540
gctccacagc gtgtgaaatc ttcccagacc agggattgaa cctgtgtccc ctgcattggc 42600
aggtggattc ttaaccactg gaccactggg gaattccaga agtagattta aacgtgaatt 42660
tcattggaga gctcagcagg gaaaggaatt ctagatctct gggcctttct attagaattt 42720
tatattctga ttttttgggg tgtaagtttc tctgttggga agcaacgcac agacaaaacg 42780
gagatttaat tggaaggata tgggatggcc ggaaggaaga cctaataaat cttcagaaag 42840
gactggagcc agagcagcaa agtgatctgg gagctggaac ctctcaggga ggattcagta 42900
ccaccatgtc cagttttgct tctttttatc agaagtcaaa gtccagggag acagacatga 42960
ccagcctggt gggggtcagg gagaggacct taaatcacag tccatgcagg gcggatcttg 43020
tgcagaaagc tagtgttctg agtcgcgctg ggcgctgtca ctcaaagaaa gagacagctt 43080
gggcagcagg agcagaaggg gccctctgcc ccacatgttc ccagagcaac gggggatcag 43140
aagcagagac ttccaccttg cagtgcagtt tgttttatgt caggggccta ggctttttgg 43200
tgtttttacg ttgagggctg acctcactga acgttcttta tcagtgaatc actgtttgtg 43260
caagaaatgt gttttttgag gggttagtcc ttgaaggttt ttcccaagga tttctcttgg 43320
tctggccttt gcacagagaa caggggggga gggtttccag aatgtccatt tggctgagag 43380
cagctgaagg tgctgtcgat tacacaggca tgctttcctg tgccacatat gagaacaatg 43440
ccctctcgag ggaatggcct ttttaagaca gtgcctaatg tggaagacgg ttgagagttt 43500
gcttctagag ctagaggggc agttttttgg tttctttggt tagacttact tggacactgc 43560
ccacagtcac tgggagctga ccaagattat gcacatgtgc atatgcatgt gtgggctgga 43620
gtggatgtct ccagctcttg cctgtacaca tcctgattgg gtctccacat ccccgccacc 43680
tcccctgggt gccctagtgt tcacagccag gtactctttg ctaatttgct tttctccctt 43740
cttgccaggt gtctgcaaat ggtatacatt gtcagtgcca tccagcgttt gccaggctga 43800
tccatggtca ctttccggga tggcagcaag gtgacttcag ctgaggatga ccctgactga 43860
aaggctgcgt gagaagatat ctcaggcctt ctacaaccat gggctgttct gtgcgtccta 43920
ccccatcccc atcattctct tcacggggct ctgcatctta gcctgctggt atgtttccaa 43980
gttgccctgg atatggtggg ccagtcgacc tcctaaccct gactgttgtg tagcccttgg 44040
actgtgtctt tttacacagt agaacttgag gctcatcccg gcccaccagt gggaagctct 44100
agtcctgggg tggaagccac tgcactagaa cagtccaggc tcgccctaat ttagtaagtc 44160
gccaggtttg ttcatattat tgagaatttc tcaaaataac gttgagatgt ttctaagaaa 44220
ctgcaggatg aataaaagtg tgatctttta attttccttc tcagcagtgg tagcttcctt 44280
ttggtatctg gttaagagca ggagcctagg agtgttgcaa gaacagtcca tttcagcaat 44340
tcttgggata ccatcagtgt tgcaggctaa tcccaggata gggttttcta catacgggcc 44400
tgtcattgcc tcacgcagga tcttttgttg catggactct ctagttgtgt gtgggcccag 44460
tacttgcagc gtgcgggctc tctggttctt ggacttagtt gtcttgcagt atgtggggtc 44520
ttaggtcctg gaccagggat cataccggtc tctcctgcat tgcaaggtgg attcttaacc 44580
tctggatcac caggcacctc cctctccagt cattttcttg tgttcctgag gagcctcctt 44640
ctgacctggt tggtccctgg gcctgccgcg ctcaccagca ctgagagctg tgccgccctc 44700
tctccatgtc tgttgtgctg tcccagggcc ccggagaacc ctgaaagctg tggctgaaga 44760
agacactgta gaaggagagg cttgatgtaa ggtgataacc aggggtcccc tctggctcgc 44820
aaacactgac aagaaaagag cccacctcgt tgtcctggtc tctgggaaga attctggttt 44880
ccagattcat tgcacatcta atgtttatag aagtttacat tgctgtgttg gaagaaggat 44940
ggttcaggac tgaactcgct gttcagttgt taatgatccc aagttcttcc ttaattagga 45000
caaggaaaga tgagcatatt cattgagagt ttcctgctgg acccttcagc aggtatataa 45060
ttaaatgtct cgttgatcct cataaaaacc ttgggaaatg gtacagttat atttccattt 45120
aaccaaaggg aggatggagg attaaagctt gcctagtctg cacagccagt gagcagggaa 45180
ccgagttcag atccaggccg gggatcctgg tgcctgcacc tgtggcactg tggccccgct 45240
ctcgtcactc tggttcagag tatttgttta aactttgtta atttgtgttg tacatgataa 45300
gatgcttgtg gctttatcct gcacctgatg aattaggagt gttctgagaa cccagctctt 45360
ggttttgctt gtattctttc ctttaagtca atttacgcat ctctgtcttt gagaatcatc 45420
cttttctagg tctggctcat gtgcttgggc agtgattctt aaagctgctc tagcatcaga 45480
atcaccagga gggcccgtta aacgaaactg ccgggctcta ccccagagtt tctcgttcct 45540
caggtctgag tgaagccaag aatgtgcgtc tctaaacaac ttcccaggcc aggggcctac 45600
atgctgagaa cactagactg tgtgtctgtc ttgaaaagtt ctaccacatc tcagctaaaa 45660
gtacttttta ttctgacttc tggagcagcg gtttgtggtg acactcatgg tcattattgc 45720
tcctatcgcc ttctgtaggg atgggtggtg tccagctccc ctgtcctaaa ttctcacttc 45780
tgtgatagcc tctgtgtatg tgcctttgca cctgggacgg cgctaagtaa atccataatg 45840
gatgaacacc ctgaattaaa cttgtcttct caatgggcag ttgaagaggt agttgtgact 45900
cgctttccac aaggacagct ctagtaacag aaaggaaagg gtgtttcttc ttgccactcg 45960
ccttctgagg attggatttg gccagctggg tctagacagc ttcccagaca gggagtgtgt 46020
gatgtgggca gcagctgtga atgtagctgg gtgcaactgg gatttatctt tgaatgaata 46080
atttgatatc acacatgtgt ttcaaaacaa attgtccttg gatttatggt aggggcctct 46140
ggtatgaaaa ctttctgacc tttgtggcta aggtctcaag tatggaagat tctgtgactc 46200
aaggtgaatt agaatggggc tggggatggg ggaagaggca aatgtgatag tatttagcaa 46260
ccagtgtagc ccagttgcag aagaaaagca aaaagcaagg gagagaggga agggtatgct 46320
cacctgaatg cagagttcca gagaatagca gagagagaca agaaggcctt tttcaatgaa 46380
caatgcaaag aaatagagga aaacaataga atggggaaca actactgatc gcttcaagaa 46440
aatttgagat atcaaaagaa catttcatgc agtgattgac atagtaaaag acagaagtgg 46500
taaagaccta atagaagcag aagagatcaa aaagaggtgg caggaataca cataagaact 46560
gtacagaaaa gatcttattg acccagataa ccacaatggt gtgatcactc acctagagct 46620
gtacatcctg gagtgtgaag tcaagtgggc cttaagaagc actgctgcca gtaaagttag 46680
tggagatgat gaaattccag tagagctact taaaatccta aaagatgatg cttttaaagt 46740
gatccaccca gtatgtcagc aaatttggaa aacccagcag gggccacagg actggagaag 46800
gtcagtcttc atcccagttt cccaagaaga cagtactaaa gaatgttcaa gttcagttca 46860
gttccgtcac tcagtcatgt ccgactcttt gtgacgccat gaaccacagc acgccaggcc 46920
tccctgttta tcaccaactc ccagagtcca cccaaaccca tgtccattga gtcggtgatg 46980
ccatccaacc atctcatcct ctgtcatccc cttctcctcc ttccctcaat cttttccagc 47040
atcagggtct tttccagtga gtcagctctt cgcatcagat ggccaaagta ttggagtttc 47100
agcttcannn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 47160
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnncaa cagaatggga 47220
aagactagag ggcctgatct cctttaggat ggactggtta gatctccttg cagtccaagg 47280
gactctaaaa agtcttctcc agcaccacgg ttcaaaagca tcannnnnnn nnnnnnnnnn 47340
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 47400
nnnnnnnnnn nnnnnnnnnn nnnaccatct catcctctgt catccccttc tcctccttcc 47460
ctcaatcttt tccagcatca gggtcttttc cagtgagtca gctcttcgca tcagatggcc 47520
aaagtattgg agtttcagct tcaaaatcag tccttccaat gaacacctag gcctgatctc 47580
ctttaggatg gactggttag atctccttgc agtccaaggg actctaaaaa gtcttctcca 47640
gcaccacggt tcaaaagcat caattctttg acactcagct ttctttatga atgctcaaac 47700
tactggacag ttgcagttat ctcccatgct agtaatgtta tgctcaaaat ccttcaagct 47760
aggcttcagc agtacttgaa tcaggaactt ccagatgtat aagctgggtt tagaaaaggc 47820
agaggaacta gagatcaaat tgccaacatt cattggatca tagagaaagc aagggaattc 47880
cagaatgaga ataccagacc tgtctcctaa gacaggttac ctgttacctg tcccctgaga 47940
aacctgtatg caggtcaaga agcaacagtt acaaccttat ttggaacaac tgatgttcaa 48000
aattaagaaa ggaatacgtc aaggctgtac attgtcaccc tgtttattta actcatatgc 48060
agagcacatc attcgaaatg ccgggctggc tgagttacaa gtggaatcaa gattactgag 48120
agaaatatca acaacctcag gtatgcagat gataccactc taatggcaga aggcaaaagg 48180
aactaaagag cctcttgatg agggtgaaac aggagagtga aaaagctggc taaaagtcag 48240
cattcaaaaa atgaagatcg tgacatttgc tgctatgact gcatggcaaa caagggaaaa 48300
aggtggaagc agtgacacat ttcctcctct tgggttctga aatcactgtg gatggtgact 48360
gcaaccttga aattagaaga cagttgcttc ttggaatgaa agctatgacc aagacagtgt 48420
gttaaaaagc agagacatca ctttgccaac aaagttccat ataatcaatg ctatggtctt 48480
tgcagtggtc aggtatggat gtgagagttg gaccataaaa gaaggcagag tgccgaagaa 48540
ttgatgcttt cgaactgtgg tgctggagaa gagtcttgag agtgcgttgg acagcaagga 48600
gatcatacca gtcaatccta aaggaaatca gttctgaata ctcattggaa ggactgacac 48660
tgaagctgaa gctccagttc tttggccacc tgttgcgaag agccgattca ttggaaaaga 48720
ccctgatgct gggaaagatt gaaggtagaa ggagaagagg gtgacagaag atgagatggt 48780
tggatggcat cactgattcg atggacttga acttaggcaa actccaggag ctggtgaggg 48840
acagggaagc ctggcgtgct gcagtccatg gggtcacaaa gagtcggccg cagcttggtg 48900
actgaacagc agcagcagcc cagttgcagc caagctgggc ggacacctgt cttagatccc 48960
acaggtgtgt ctggcggaac atcagtcctg ggaacgggtg gtggccctca gggtggactg 49020
ggctggcgag agggagtgga gactcatctt cactgagcac tggcttcgtg tgcaagcgct 49080
tccacacatg ctgtttcatt tgctcgcctg acgtccttgg aggaggtggt tcttccctag 49140
ctcctctgct gctgatgaaa cttgtaggga gagatagtaa gtggtgtgct gcaactggca 49200
ggtctgtgtg gtggatccac atctgtggtt tctccacttc actggggtga catgaacttt 49260
atgaagaaca ctttggtgct gttaactttc actgcagggg tctgctcctt gaccaagaag 49320
ctggagaaag agagtctcag ttgcagtggg ccagtgggcc aggatctgcc tagacagagg 49380
acagagaggc tttttgaggt agtggcccta catagtagtc gttgaggaga gtgcatgcag 49440
ttgagtttta tagctacctc aatcaagatg gctgtagtat atgccaagag ctgtgccaga 49500
tggtaatgct gaacacagac cctcccacag tctcagcctc agagagacaa ttgcagtgcc 49560
actggatttt tttttctttt aagtttgtgt gtttattatt attaaaaaaa ataatttttg 49620
tatatttctg ttggctgcgc tgggtcctct tgctgcatgg gcttttctct agttgctgtg 49680
cgcggggctg ctctgcagtt gtggtgtggg cgtctcattg cacgggcctc tctcatcacg 49740
gagcatgggc tctgggcgcc tgacttcagt agtgctggca cacaggttta gttgcccctt 49800
ggcatgtggc atcttcctgg accagagatc aaacccacgt gtcacgcgtt ggcaggtgga 49860
ttttcatccg ctgagccacc agggaagccc ctgcagggtg gatccttaac cactggacta 49920
ccagggaagt tcctgtaatt tttgttttta attgaaggat agttgattta ttatgttgtg 49980
tcagtttcta ctctacagca aagtgattcc gttatccatg tatacatact atttttcata 50040
ttctttccat tatggtttgt tacaggatat tgaatatttt tccctttgct gtagagtagg 50100
accttgtttt atctattttt taatatagtt tttatttgct aatcctaaac tccttattta 50160
tccttcccct ttcccctttg gtaactggtt ttaaatttct atgtctgtga gtctgtttct 50220
gtttgtaaat aagttcattt gtgtcatatt ttagcttcca catataactg atataatata 50280
atacttgtct ttctcttgct gagttcactt cgtatgatca tctctgggtc cgtccatgtt 50340
gctgcaaatg gcgttatttc attccttttt ataactaata ttcctttttt ttttttttta 50400
atgtgctaca tcttctgtat ctactcatct gtctgtgggc atttaggtgg tttccatgtc 50460
ttggctgttg taaggagtgc tgctgtgaac ctaagagtgc ctgttacctt tttgaattag 50520
catttgctcc aaatatattc ccaggactgg gactgctgga tcgtatggta gctacagtgg 50580
aagtgaaaaa tagatttaag ggcctagatc tgatagatag agtgcctgat gaactatgga 50640
atgaggttca tgacattgta caggagacag ggatcaagac catcctcatg gaaaagaaat 50700
gcaaaaaaag caaaatggct gtctgggaac gccatacaaa tagctgtgaa aggaagagaa 50760
gtgaaaagca aaggagaaaa gtaaagataa aagcatctga atacagagtt ccaaagaata 50820
gcaagaagag ataagaaagc cttcttcagt gatcaatgca aagaaataga ggaaaacaac 50880
agaatgggaa agactagaga tctcatcaag aaaattagag atacaaaggg aacatttcgt 50940
gcaaagatgg gctcgataga ggacagaaat ggtatggacc taacagaagc agaagatatt 51000
aagaagagat ggcaagaata cacagaagaa ctgtacaaaa aagatcttca tgacccagat 51060
aatcacgatg gtgtaatcac tgacctagag ccaggcatcc tggaatgtga agtcaagtgg 51120
gccttagaaa gcatcactta attttccaag ccaggcttaa cagtacatta tctatgaact 51180
tccagatgtt ccagctggtt ttagaaaagg cagatgaacc agagatcaaa ttgccaacat 51240
ccgctggatc atggaaaaag caagagagtt ccagaaannn nnnnnnnnnn nnnnnnnnnn 51300
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 51360
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 51420
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 51480
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 51540
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 51600
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 51660
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 51720
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 51780
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 51840
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnntat accaacctag atagcatatt 51900
caaaagcaga gatattactt tgccaacaaa ggtccgtcta gtctaggcta tggtttttcc 51960
tgtggtcatg tatggatgtg agagttggac tatgaagaag ggtgagcgcc gaagaattgg 52020
tgcttttgaa ctgtggtgtt ggaaaagact cttgagagtc ccttgaactg caaggagatc 52080
caaccagtcc attctgaaga tcagccctgg gatttctttg gaaggaatga tgctgaagct 52140
gaaactccag tactttggcc acctcatgga agagttgact cattggaaaa gactctgatg 52200
ctgggaggga ttgggggcag gaggagaagg ggacgacaga ggatgagatg gctggatggc 52260
atcactgatt cgatggacgt gagtctgagt gatgggaggc ctggtgtgct gcgattcatg 52320
gggttgcaaa gagtcagaca ctactgagcg actgaactga gctgaataat tagtgctgtc 52380
gagcatcttt tcatgtggtt attggccatc tgtatgtctt ctttggagaa gtgaatagaa 52440
cgcttttagt gatttcacta gatgcccagg ctccattcaa ctgcttacct gtattgtaca 52500
tggaacgaga gacttgttca gcttgatgaa gggactgctg ctttcgttac ctctgtctgg 52560
ctctagcagc ttcctgagct gtgcacctgt tcatcatcac agggtcaccc tgggagccat 52620
gaatgcgctt tcctttggga aaatctgatg aaacttgtag caagtaggca ctgtggcgac 52680
aggtgtctgt ttacatttcc tagagctagt tcagccacca ggatgcccag tagcggccca 52740
gcaaggcaga gggtgctgtt gcttgggcct gctgtgggaa gtggtgggtg caccgtggcg 52800
tgaaggaaca gtgtctgggt gccaggccag ctgggttgcc gtccctgggg gccagaggtt 52860
tatgtggggg tcagtgggtc acttatgatt ccataacgtg ctgctcgtgg ttacagaggg 52920
tgaattttac cttagagagc aagttggaat caccatgaga ccattccaaa ccccctgagg 52980
gaggtgaatc cttcagggtg tgtgggtatc ccagtgcaga catggccctt tcctcctccc 53040
ttttctctgg agcaaagcag ccctttcagg ctgagactgg acgtctcggt tgtggtggcc 53100
tctgctctca acctctctct cccgtgtctg ccgtggctca ggttttccca tgattgtcgt 53160
ggcccctttg caggtgggca tacaggggct catagagcag gctccttctt tctgtaccct 53220
gtgaccactc tgaacatgat tagattcttt tcacgaatga gaaagaaatc tgagtaacag 53280
aagccgagtc tgcacctgtg ctttgagagc tgggctgatg ggccaggaag gacgtccgag 53340
caccatggac ctgtgtcccc aaacccagat gcaggagccc agggcccagc tacagcagcc 53400
gctcctgggt cctgttcagc actccgaagc cagaggctcc ctccaaacag aagttacccc 53460
tggccctgca cacaaactcc ggaaaagctc tgaagggctt ggaggagatc aaaggcgccc 53520
ttatcaaccc agacttcctc aaacagaaga gagatcagga gatctcagaa gtttcccctt 53580
gtagactttc accgccccac cctagttctg cgctgctctc ccctgagaag gggagagagg 53640
aagcacgtcc gactgctggt gcctccggag gggagtcctg tgccacgccc ccacgtgcca 53700
tctttctggg tgctcttcct gtgtgtcttc agtgtctcct gagctcccat cgtaacacca 53760
tcgttaccca gtgcagcatg aaggtgcagg gctgcctcct caaaaggcag ggggaaagta 53820
ccactcaagg tgctgcagta tgctcagatg cgagtaggtg aaaggcttcc tcctgccaag 53880
ttgctcctgc catccactgt gctgtggtgc agccagcctg ggataagcca cggccaacgc 53940
ctcacccaac tccaggaccc agcaaggtgt gcgctgctga acacctactg gttttggttg 54000
ggcacctgta ggcagcagca gcacatggat acctggactg ggaggggatg gccagatcct 54060
gggacgcagg tgggcagggg tgctggtggt cacgcacctg tccaagggtg gagggaccac 54120
ctgtgaacct atactccgca tcatgcgccg atgtgatgga tttggtttat gaagcacaaa 54180
tcaaaagata gatttgttaa gaatttctac atatctactg cagagcgtta aaccccaagc 54240
tccaggccct tctgaacgtg gggccttacg cagccacata ggtgcacacc atgaagctag 54300
tccttggtac agcgtctggt aggttaaaaa tcagcctgca catcttgaac atcttccgtg 54360
tggctggtat gaggatgcga aagttagaag gacatgttcc cacctcacat atcttacatt 54420
aattaagcag gtgaattgag gagcagtgtc tgcaagttgt cgtgggagtg tagaagagag 54480
gtgcctaact gcttgggttg gaaagatgag gtggccttgg aggatacacg ggagtttggt 54540
cagcatttag tgggtagagg gcatgtttta ctttggtctc cctgagacag ggatttgagt 54600
gcagcttatg tttatttaac ttatatgcag agtacatcat gagaaacact ggactggaag 54660
aaacacaagc tggaatcaag attgccagga gaaatatcaa taacctcaga tatgcagatg 54720
acaccaccct tatggcagaa agtgaagagg aactcaaaag cctcttgatg aaagtgaaag 54780
tggagagtga aaaagttggc ttgaagttca acattcagaa aacgaagatc atggcatccg 54840
gtcccatcac ttcatggcaa acagatgggg aaaaatggaa acagtgagag actttatttt 54900
tgggggctcc aaaatcactg cagatggtga ctgcagccat gaaattaaaa gacgcttact 54960
ccttggaagg aaagttatga ccaacctaga tagcatattc aaaagcagag acattacttt 55020
gccaacaaag gttcgtctag tcaaggctgt ggtttttcct gtggtcatgt atggatgtga 55080
gagttggact atatagaaag ctgagcacca agaattgatg cttttaaact gtggtgttgg 55140
agaagactct tgagagtccc ttggactgca aggagatcca accagtccat tctgaaggag 55200
atcatttctg ggatgtcttt ggaaggaatg atgctaaagc tgaagctcca gtactttggc 55260
cacctcatgc agagagttga ctcattggaa aagactctga tgctgggagg gattgggggc 55320
aggaggagaa ggggacgaca gaggatgaga tggctggatg gcatcactga ctcgatggat 55380
gtgagtctga gtgaactccg ggagttggtg atggacaggg tggcctgaca tgctacaatt 55440
catggggtca caaagagtcg gacacgactg ggcaactgaa ctgaactgag ctgagcttat 55500
gtgtcacaca cgactgagca acttcacttt cacttttccc tttcttgcgt tggagaagga 55560
aatggcaacc cacttcagtg ttcttgcctg gagaatccca gggacctggg agcctggtgg 55620
gcccccgtct atggggtcgc acagagttgg acacaactga agcgacttag cagcagccgc 55680
agcagcttat gcgcaggatg gaatgaatag tggtcagtgg gtgggagagg gagctggaag 55740
gggaggtaca ttatccagca agtttacacc acgggccacc ccagagtcac attcggggac 55800
actgaggaac agtgcaggtc ttccgcctca gagctccctc tccgatcggg ggagctgcac 55860
cctctgccag gtcagcagac tcattcccag ggccgcatag gaaggccacg tggagcctct 55920
gtcacaaatt tttctttggt tgttttgttt tatatgttgt tgttcagtcg cccagtcgtg 55980
tctgactctt tatgacccca tggactgcag cacgccaggc ttccctgccc ttcaccatct 56040
cctggagttt cctcaaactc atgtccactg agtcagtgat gccatccaac tatcttatct 56100
tctgttgtcc ccttctctcc tcctcccatc agtctttccc agcatcaggg tcttttccag 56160
tgagtcagct cttcgagtca ggtgaccaaa atatcgaagc ttcagcatca gtcgttccag 56220
tgaatattca gggttgattt cctttagaat tgactagttt gatctctgtg cagtccaagg 56280
gactctcaag agtcttctcc aaaaccacag ttaaaaagca tcagttctgc actcagcctt 56340
ctttgtggtc cagctcttac atccaccatg actattagaa aaactatacc tttgactata 56400
cggacctttg tcagcaaact aatgtctctg ctttctagta ggctatctag gtttgtcata 56460
gcttttcttc caaggagcaa gggtctttta atttcatggc tgcagtcacc atctgcagtg 56520
attttggagg ccccaaaaat aaagtctctc actgtttcca tttttcccca tctgtttgct 56580
atgaagtgat gggaccagat gccatgatct tagtgttttg agtgtcgagt tttaagccag 56640
ccttttcact ctcctctttc accttcatca agagcctctt tagttcctct tcactttcag 56700
ccattagggt ggtatcatct gcatatctga ggttattgat atttctcttg gcaatcttga 56760
ttccagcttg tgcttcatcc agcccggcat ttcacattat gtactctgca tataagttca 56820
ataaatatgg tgacaatata cagccttgac agtatactcc tttcccaatt tagaaccagt 56880
ctgttgttcc atgtccagtt ctaactgttg cttcttgacc tgcatacaag tttctcagga 56940
ggcaggtaag gtnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 57000
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nncacattat 57060
gtactctgca tataagttca ataaatatgg tgacaatata cagcgaactg tggtgttgga 57120
aaagactctt gannnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 57180
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nncacagttt 57240
gttgtgatcc acacagtcaa aggctttagt gtagtcagtg aagcagaagt agatgttttt 57300
ctggaattct cttgcttttc ctagatccag tggatcttgg caatttgatc tctggctcct 57360
ctgccttttc taaatccagc ttgaacatct gcaagttctc agttcacata cttttgaagc 57420
ctagcttgag ggattttgaa ctttaccttg ctagcatgtg aaatgagcac agttgtccag 57480
tagttggaac attctgtggc attgcccttc tttgggattg caatgaaaac ggaccttttc 57540
cagtcctatg gccactgctg agttttccag atttgctggc atattgagtg cagcccttta 57600
agagcatcat cttttaggat ttgaaataac tctgctgaaa ttccatcact tccactagcc 57660
ttgttttata gtaatgcctt ctaaggccca cttgacttca tctccatgat tgtctggctc 57720
taggtgagtg atcacacacc tatggttatc tgggtcatta agaccttttt tgtacagttt 57780
tgtgtattct tgccatctct taatatcttc tgcttctggt aggtccctgc tgtttctgtc 57840
atttattgtg tccatcttta catgaaatgt tccttgttat ctctgatttt cttgaagaga 57900
tctctagtct ttcccattct gttgttttct ctttctcttt gcattgttca tttaaaaagg 57960
ctttcttatc tcagcttgct attctctgaa actctgcagt cagttaggta tcttcctttt 58020
ttgccttgcc tttcgcttct ccttttttca gctatttgta agccctctgc agacaaccat 58080
tttgccttct tgcatttctt tttttttttt tttttgcatt tctttttctt tgggatggtt 58140
ttggtcacca cgtcctgtac agtgttaaga acctccatcc atagttcttg aggcgctctg 58200
tctatcagat ctaatgcctt gaatctgttt gtcacttcca ctgtataatc ataagggatt 58260
tgagtaaggc catacctgaa gggcctagtg gttttcccta ttttcttcaa cctaagtctg 58320
aatttggcaa gaaggggctc atggtctgag ccacagtcag cttcaggtat tctttttgtt 58380
gactgtatag ggcttctcca tctttgactg caaagaatat aatcagtctg atttttgtac 58440
ggatcatctg gtgatgtcca tgtgtagagt tgtctctttg tattgttgga agaggatgtt 58500
tgctatgacc agtgcattct cttggcagaa ctctgttagc ctttgccctg cttcatttcg 58560
tactccaagg ctaaatttgc ctgttcctcc aggtatctct tttttttttc ccctccaggt 58620
atctcttgac ttccaatttt tgcattccag tcctctatgg tgaaagtggc atcttttggt 58680
ggcggggtgg gggtgggggg tgttaattgt aggtcttctt ggttttaacc cttttaaaat 58740
gtaaaaatca ctttgaactc acagaccaca tgaatacagg acatggactg tagtttgctg 58800
acccctaatc tgtacaataa taacatgaac caccgactgg gctgcttcca gctagcatta 58860
atcctcagtt ggcacttggg gcccatctct gtgaggcaga gaggcctcca gcagcagtgg 58920
aagactctca ggtgaagata tgccagtgct ggcagctgga aattgagcca gcatgtccag 58980
agatcagatg agggggaaca agggtagggc ggcagcaggc cctggagagg tgttgggtgg 59040
ccagcgtggg ccctgtgggc acagcaacag aggtgtgtgg gctgggaggt ggggagattg 59100
agagtgtact tgtacctgat gaggaaacaa gtgatttcag caggagaagc aggaagtcca 59160
gctagactag tgcgttagtc cagataagag ttgatagctg ttgctcagtc taaggggagg 59220
ccctggagat ggtgagatgt ggccaagtct ggatgtattt tgaagatgga gtctttggga 59280
tttttctgag caccaggtgt ggagtgtgag agagtgcaag ctcagagtgc ttggtctgag 59340
cagctggatg ggtggagctg agacaggaaa ttgagggagg ggtttggaga cttggttcct 59400
tccttgtgcc cctgtaaggt cagagtaagc cacgacagaa tctggcttac tgaaacgagt 59460
ttgcagaagc aatgtggggt ggtggtagaa acctccagtt tctgtctttg gtcttttttt 59520
tctgaccttg ataaagtgag tgcttttgct tataaaattg cccgacactt ttttccaagc 59580
cttccttttg gtctcacatt tggtagccat ggacggtgat gattaccttg cattttgtat 59640
ttctgtagaa tctttttctt gtgcttatat tagaaggaat ttatggtcat ttttgaaaaa 59700
acaaaacaaa actgtaatac caggtagtat agcatgatgt taagagagtg gactctgggc 59760
ccagactgcc tgtgttcaca tactggttct gtcactttct tgggggagat aatagcttct 59820
gcgtgcctcg ttgggctgtg gtgaggctta aatgagcaaa aaagatggaa ggcacttggc 59880
acatcgcagg ttctcagtga gagttagaat ctgtcgtcat tgttacagag acggaaacag 59940
gcaggttcac ggtcagtggt aaggaccgtt ttgggatgag tatgaggctc tttggtagct 60000
cctaggaggg gaggccagag aaggcaatgg caccccactc cagtactctt gcctggaaaa 60060
tcccatggac agaggagcct ggtgggctgc agtccatggg gtcgctaaga gtcagacacg 60120
actgagtggc ttccctttca cttttcactt tcatgcatgg gagaaggaaa tggcagccca 60180
ctccagtgtt cttgcctgga gaatcctagg gacggcggag cctggtgggc taccatctat 60240
ggagtcgcac agagttggac atgactgaag cgacttagca gcagcagcag caggagaggc 60300
cttattaacc tggattttgg ggggagcgga aggacttcct gtggaaggaa tactgcagct 60360
gaggcttgaa actgagttat cttgaagaag aaggggcaag agccaggtgc agcgcctcag 60420
aagcagaagg ggagttgtat gtggctccag ggcaaagttg gagaatgacc gtgagccatt 60480
ttaagcattt caaggtctgt ggctgtttca gaatagattt catcctagga aagtggatgc 60540
tctggggtgt gctgcccttc tttttttttc ctgctagaat gttttgttgt tgtttttgtt 60600
tagttgctaa gtcacgtcca agtctttgcg accccatgga ctgcagcatg ccaggctttc 60660
cggttcttta ctatctcccg gagcttgccc aagttcatgt tcattgagtc agtggatcct 60720
atctaaccat ctcatcctcc gtcgccccgt ttgcctcttg tcctcagtct ttcccagcat 60780
caggatctct tccacttagt cggctcttca gatcaggtga ccaaagtatt gaagcttcag 60840
catcagtcct tccagtgaat attcagggta ttgatttccg ttaggattga ctggttcgat 60900
ctccttgctg gaatgtttaa actcctggaa ttcacagatg ttttaaatat ttcaaatctt 60960
gagaaacagg ctgccttcag tttagtgagt gtgttttggg cagctactgt gtggaaagtg 61020
actgtagata aatacaacat atggcccacc ttcatcttct agtagagcta gagctctagc 61080
agccttagct ctgggccctg gactcctctc tacacccagg ggtcagccca gcccttgtgc 61140
agagttttcc ccaacagaac cttagctaag tccagagaca gctcttgata cctgcttcca 61200
aacaggtgaa ccttatagct tttggaagca gcaagagaaa agcaactctt cacataaaag 61260
gaattttcaa tagattaatg gctgatagaa accatcagtt tagttcagtc actcagtctt 61320
gtccaactct ttacgacccc atggactgaa gcatgtcagg cttccctgtc catcagcagc 61380
tcctggagct tgctcagcct catgtccatt gagtcagtga tgccatccaa gcgtctcatc 61440
ctcttttgtc ccttctcctc ctgcctttgg tctttcccag catcagggtc ttttccaatg 61500
agtcagttct ttgcagccaa tggccagagt attggaattt cagcttcagc atcagtcctt 61560
ccaatgagta ttcaggactg atgtcctttg ggattgacta atttgatctc cttgcagtcc 61620
acgggactct caagagtctt ctccagtacc atagttcaaa agcatcaatt cttcggcact 61680
cagctttctt tacagtccaa ctctcacatc catacatagc tactggaaaa accatagctt 61740
tgactagatg gacctttgtt ggcaaagtaa tgtctctgct ttttaatatg ctgtctaggt 61800
tggtagcttt tcttccaagg agcaagcgtg ttttaacttc atgactgcag tcgccatctg 61860
cagtgatttt ggagcccccc aaaataacat ctcttactgt ttccattttt tccccatcta 61920
tttgccatga cataatggaa ctggatgcca tgatcttagc tttttgaatg ttgagtttta 61980
agatagcttt ttcaccatgg aggcatttaa agtcctgaaa ggaaaaaact caaccaagag 62040
ttctatcttc tgcaaaactg tactttggta atgaaggcga aattaaggca ttttcagata 62100
aacaaaagct gagcaaattt gttaccactg gacctgccct acaggttgaa accataagag 62160
aaaataaaca ctagtaaaga tgatcagtat tgctgtgctt ttggtttggt ttgtaatttc 62220
tttctttgtc ttttgtgatt taaagggcag gtgtattaag tgtaacataa aagctgtgtt 62280
aatgagaata aatgtataaa gtgtaatctg tggcagtaac agtataaaag gggaaagaca 62340
ggatgtactg tcagagcgta tactgtggat gctaagctct cagtcagttg tcttgttttc 62400
acgattgctg atcctttctt ctgtctgctc agatttgctt ttgagctcct ctgtaataat 62460
actattcagc ctagattgtt acaaggtttt gttgttgttt tttaattttt ggctgtgccg 62520
agtctttatt ggtgtatgtg ggcttctccc tgcactgggt tctcttgtta cagagcgtag 62580
gctctagggc gcatggcttc agtggttatg acacgtgggc tcagcagtta cagctcgcag 62640
actgcagagc gtgggctcag tagtttcctg cagcatgtgg aatcttcctg gaccaaggat 62700
tgagcacgtg tcccttgcat tagtggtgga ttcttaataa ccactgaacc accagggaag 62760
tcctataagt tgttaataat agaactccca aggtaactag gggcttccct tgtagctcag 62820
ctggtaaaga atccacctgc aatgtgggag acctgggttt gatccctggg ttgggaagat 62880
cccctggaga agggaaaggc tacttgctcc agtactctgg cctggagagt tccatggact 62940
gtatagtcca tggggtccca aagagttgga cacaactgag tgacttttac tttcaaggta 63000
accactaaga aaataacttc taagatatat agaacaggaa agtagaagtc aatcaaagtg 63060
gcacactaca aaaaatcaac cccctccctg tttttttttt ttttaaaaag caatggagga 63120
attgacgagc aaaaatcatt tgacaaaaca aatagctgta cagcataagt caatccttcc 63180
ctgtgggtat tcacattaag tataagtgga tcaaactcgc ctactaaaag acaatttgat 63240
ttttaaaaga atctagactt ccctggtttt tcatggtgaa aaatctgcct gtccagatct 63300
gtgtttctgt gcacacctct tcatgtccac acccaggttg aacgcgcctt tttttttttt 63360
taatgcattg cttactttgt cttagtgtta tgcatgttat gttggtaaag caaagcatgt 63420
ttgtttaaac ttgcattaat ttttaaatca acactgattc tggacagagc taacctctca 63480
agcttcaact taatttatat tgattttttt ttgacttcct gatgtacagc aacctgtatc 63540
agcaggtatc aagagctgtc tctggactta gctaaggttc tgttggggaa aactctgcac 63600
aagggctggg ctgacccctg ggtgtagaga ggagtccagg gcccagagct aaggctgctg 63660
gagctctagc tctactagaa gatgaaggtg ggccatatgt tgtatttatc tacagtcact 63720
ttccacacag tagctgctca aaacacactc actaaactga aggcagttta tctgaaggca 63780
gtgtatcttt cttattatag gccaaaaaca aaatgtattc aatgtaatac tataatatat 63840
atatattata tattatataa tactatgtaa tactataata caatgtaata ctataatttg 63900
caatttaatt acaatcaatt tttgatttcc caaattaatt cttaccattt atataaaatt 63960
atattttagg caatttaaaa atatttagaa atagttttat tctctgatac aggcactgtt 64020
atactccctt caggaaggaa gcctgacagt ctgacattta aaagatatat gactgaatag 64080
aaaccctatg aagttaatgg gtttaaattt aaaccatttt caaggattat ttttttggaa 64140
agttttcttt cttaagggtc tgattaataa ctgctaataa aaaaaatacc attgaaaatg 64200
tatgaaaata ccattgaaaa ttctattgct ctccacacat ttgaaaaatc cagatccagt 64260
tatatacaga attcctactt tattgcttag agtgccttgg attaccagaa taatcccttg 64320
gagtacctgg gaccaaggat ctgttgctag taaaaataat tattaaatta tctttataac 64380
attttaccta attgtttatt atttagaatt ccttctatat gtgaggtaaa attttataaa 64440
taaaatattt aaatagtaaa agaaaaagaa aagaatctgc ctgctaatgc gggggacaca 64500
ggtctgggaa gatcgcaaat gggaagatcg caaatgccgt gggaaaatcc cacatgccga 64560
ggagcagcta ggcccacaag ccacaactgc tgagcctgtg agctacagct acgaggcccg 64620
cagacctaga gcctgtgctc tgcaacagcc atgagaagcc tgcgaattgc aaaggagagt 64680
agccccagct cgctgcaact agagaaagcc tgtgcgtagc aacgaagacc cagtgcaaca 64740
acaaaaaagg cagcacagtt tgtatactta agaaaagtgt ctgcgtgctc tctgtttttg 64800
cctgtgccgg gtctttgttg cgacacctgg gctctgggct gcggcacaca agcttctctt 64860
cttgttgcag tgcatgggtt caagagtgtg tgggctcagt ggttgtggcc cgcaggctcc 64920
agttgtggtg cctggggaga cactgtaggc gtccgctacc ctttggatat tagaacacaa 64980
agaagttgca agtaaaaggt tggaaaatga tattccatgc taaatgatac ccaaaagaga 65040
gctgacgtgg ctatattatt atcaaacaac attaaaaagc ttattagaga caaagaagga 65100
ggacactata tattgatgaa atattgatca ttgctggggt ccagccccgg tggatccagg 65160
gaattcgaag cggggacggc gtcgacgagg atcaggaaac aactgcttaa ttaaacgtta 65220
attaaggata taaagagtaa tagaataagg atagctcagt gaggaaattc agtggagaag 65280
agaggctgaa ataaggatag ctcagtgagg aaattcagtg gagaaaagag gctgaataat 65340
tcagccagaa ggtgagagaa agaacgacat ggggagacca agttttggtg aacaaggccc 65400
gcactttatt ttccaaagta gtttttatac cttaagttat gcatagagga taatggggga 65460
aggggtagag tcatgcagca agccaggctt tcttcctgca aacttatcat atgcaaaagc 65520
ttaggtgatt tgcatcatct tctggcccgg aggcctgtta acattttaag accctttctt 65580
cagaaagctt atttttctct aaaggtgatt ggtcaggagc caccctccaa aagcattaga 65640
taaagttgca ttcctacaga gcaaaggtgt ggtgggctat aacaagaaaa agaattaact 65700
caagggtccc aggttacaaa cattaaagct actacttaca ccaattatat taatcaagac 65760
actgccaggg acacagcagg taagggatat ggaaacttag cagcaaacat tggcccaaca 65820
agtgaaaatc ccttcaccaa tccaatttct aatcaatctt ttaactgctc aaaggaatct 65880
gtgtttagac agtttagaac atctcatgcc tctcacagtt gggaagctct gagcaatcac 65940
atgtggccgg aaaaacctat tcaggcaggc tagaggattt ccaaaggagt ttgtaggttg 66000
aaacactgtc acacccagga attgttaact ggagctgtaa gctaactctt ttttcagaga 66060
gaggtagtgg gggacagccc cccgtaaagt cagaggtgta ggtgaaagca caaagcagaa 66120
agtaggcaga ctctggtttt gggggtggat gctcgagaat ttccaggggg actcctgagg 66180
ctcgatcccg cctttgcgta tgccgaacct ccttcctcat gacctttgtc atgggtggag 66240
cgcctcacgc tggctcccgg caatgataga attccagttg agctattcca gatcctgaaa 66300
gatgatgctg tggaaagtgc tgcactcaat atgcaatatg cactcaatat gcaatatgcc 66360
ggctcccggc agatcatatt gatatgctga cactatatat atgtttcagt ataacaggag 66420
gatataatga ttataaacct attaacacct aacagactcc taaaatattt aaagcaaaaa 66480
tgggcagaat tgaaaagaga aacacacagt ctccgtgaca gtggatctcc gctttcagtg 66540
atggatacaa ccagacaaag tcagcaagga aaatggagga cctgagcaac cctgaaaccg 66600
acgagactag tacatgttct tcccaagtga acacggaaca ttctccaggc cagaccctgt 66660
gttagatcac aagtctcaat aaatttagaa agacggaaat catacagagg atcttttcca 66720
gtgacagtgg aatgaaacta aaactcgaga aaagaaggaa aattggaaat acgtggaaat 66780
tgtccaggtg gccaataagc atatgaaaga taagcataca ttgtttgctg tatattgaaa 66840
ccacagagct ataccagcac ctcctccttt gctatgctat gctatgctat gctaagtcac 66900
ttcagtcgtg tccgactctg tgcgacccca tagacggcag cccaccaggc tcccccgtcc 66960
ttgggattct ccaggcaaga acactggagt gggttgccat tttcttctcc agtgcatgaa 67020
agtaaaaagt gaaagtgaag tcgctcagtc atgtctgact cttagcgacc ccatggactg 67080
tagcctacca gactcctccg tccacgggat tttccaggca agagtactgg agtggggtgc 67140
cattgccttc tccgcctcct cctttaaatg gttccagtta attggactga caagatcaag 67200
aggtggagca gttgaaactc ccatcgcgcc accagcggga acacaaattc aaataagtac 67260
tttggaaatc tggtgtaatc cacaaagcta aacatgtgta tgctccacaa cccagccatt 67320
tcgttcaagg gacatacctt acagaaatga gtacttacat aagaatgagt gtatacataa 67380
acatttccat aatttctctt cttaatagtt tcagctggaa acagccaaat gttcctcaac 67440
actagaatag ataaatgcac tgtaatatgt tcatttggtg gaatagcgcg tatgcatgaa 67500
acagtgcgta tatatgaaac tgcatgcacc agtgtggatg aacctggtag atgtaagttg 67560
aaacagccag tcacaaagga gtacgcagtg gaatgggtga tttcagttat atgccagaag 67620
aaacaagcag agctaatttg tgattataga aattctgata gtggtttgtg gtagacgatg 67680
cccttcacta gcgcacaaca ccaccttcta aggttctaaa gatattttgt agcttgatct 67740
acataatgag tacacaggag tatgtatgtg taaatattca ttgcactcac tgtatgctta 67800
agatttgtgc attgtagtac ataaaatgta attctcagtt aaaaaaaatt tttttttgac 67860
cacatgtggc atgcagaact tcctcgacca gggatcgaac ctgcatttac tgcagactcc 67920
ggaagctcag agtcttaatc attggcccac caggaaaatt ctaaaaaaaa aaaagttcta 67980
aagaaatgaa gtcagaaaca aaagcacatc catttgccaa ctttttgatg ttagtccaag 68040
ctttttcctt tgccagtggt ggatccattg ttttcaattc agcctggtct agtgtaaacc 68100
ataccctcag tgtgttatac aaaatcttat ggtctgtcct tttaaactga agcagttttc 68160
gcagcagtct gaatcaggat ccttctggat ttttggttcc ctgttttttt tttttttttt 68220
ctttttcttt ttcttttttg gccacactgc ctggcatgtg gaacttccct gaccagggat 68280
cgaacctgtg cccctgtgga gtcttaacta ctaggccacc aaggaagtcc ttccccagtt 68340
ttttcttgtt gtcttacgtg catccgatat gaccagaagt ttgtttagca tcttgccttt 68400
attacatctc tcaaaatttt cagccagtaa tctgtttcat taagtagttt atgaattgcg 68460
tttcctgtga ccaaaaagga gcttgaaaat tctaatttag aggctcctgc atttccttgt 68520
agccctgaag ttcgatgact ggtatttcgt acatttgtgc agttctccta gcacaggagg 68580
ggagtgcagc tgcagtgatt cccacgtcac tgttacctca gcatggattc tgcctgccgt 68640
catgtcctga cttctctctc ctttttgtcc atcctagcta cccactgctg aagctgccct 68700
tgccaggaac aggacccgtg gaattcacca ctcctgtgaa agattactcg cccccacctc 68760
tgacctctga ccacaagcct ggagagccca atgagcagcc agagtgggta ggtgctcagc 68820
gtgtcctgag gagcgccctg ggcattgggt gcggattggc cgtggcaggg gttctgtgtg 68880
gagtgagggt ggtcagcttc tgatgggcga atgcttaaca cttgaaccac tttataaagg 68940
cactgaaaat atttagctta catttaatag tacatccagt cacacattcc tgttttgaaa 69000
ggaaacacta aatggcatgg caggaaggtg actgtcctgg aaaagctggg ttgtggttgc 69060
tgtagctgcg gctggctggg tctgggtcca tatactgtgg gtgctcgggc caggcagtgc 69120
cctggcaaac ggacctctcc tccttgagcc caagtggttg cgggaaccac tgagtatccc 69180
tggagaatgt tttatcttct gagtcccatc accatttaat gttagcagtg agggcttagc 69240
tttttcaaat ctggtaggtg ctgttttatc ctcacagtgc agtcaggtaa agcgtgcagg 69300
ttctgcttgt tcgcctgttg tgcgattgag gaagctggga atagcagtgt gcctcagttt 69360
cagttcagtt gtcatggggt cagcactggg ttagaactcc agatctcctg acctgaagcc 69420
agctgctact tttgaatcgt gctttcctca gccagctgtc tctgagctga gcatgaatgc 69480
aaaacagaaa gaaaacctac aggaatgcaa aacctccagg tgagggtctg ggctgcggga 69540
tgtaacccgc gggaactctg gactcattat ttggaaacct tagaggaaat gataagctcg 69600
tcctgccagc tgtggatgac atgttcttcc cttgcgtgct gggccctggt cccgtgggtt 69660
ggtgccgggc ttgctgagcc tgttgttgag gagcagagcc cagctcaggg cacacagctc 69720
ctcttctccc accctttctg tgccagtgat tgcacattcc ttcctgttgc ctttctgggt 69780
aatgtagcag ccaggtaact tgatgtcagc tttgctctaa tgttgctaaa gtagagatct 69840
ggttagatag gtgtgtgtta tgactacaca tggtttcagg aggaagtgga gaacacaggc 69900
tcagtggtac tcagccacgc aggttagggt gagctgatga ggcggaaacc agttcatagc 69960
ttcatgtctc agcttgacac ttcgctcatt gtgggatcaa gccttttgcc tcttttactc 70020
tgtcttaaaa aaaaaaaaag tatttattta tggctccact gggtctttat tgcagcaggc 70080
gaggttctct ctagtagagg tgcacgggct cagttgccca gcagcgtgtg gggtcttagt 70140
tcctcaacca gggatcaaaa ctgcgtcccc tgcattggaa gtagaattct taaccactgg 70200
accaggagga aagtccctcc attaacctct tgatggggtt ttaccacata atggagttga 70260
tggttcctgg tcacaagggt agtctgcgtt tgtgagtgtt ttgtgactag tagagttcag 70320
tgggcctgat ggtagttagg ggtctatcca aggtcagggg ttcacttgtt tgtgagccct 70380
ttccacttct tgatgtcctc tttgggcctg ggatgatgat agtgtggggg tacaaaatag 70440
cttgagggtt tctctttctc actggggtcc gcagcccctg aaaggttgag aaagagatgc 70500
agccctggct cagtcacctg gtgtcaggcc tctccgtggt cagttacctc accaggattg 70560
actgttgtaa caataaaggt cagcaaggca gaacttgtaa aggattgctt taagtacaag 70620
gaacagaaaa ctcagcccaa acctggggaa gtgagaaggg catttcgggg tcatagagct 70680
cacccacagg caggacttac taacggacag catgggttag gcctcagaag gagtccatcc 70740
ctcaactgta ccctctccgg gtcagctcac tgtcctctcc ctaatggggg ctacagcaga 70800
ttcagccctg tgggtgccca cttggctctg catgggatta cctgcctgct cccacccgag 70860
accctgtgag cagggaggtg ctttgctgat tggcttcatc accacactgc gggtgagaga 70920
gactgtttcc aaaggaagat taggaagtgc aggccctggg cagcacagca caagcgtctg 70980
ctgctcacag caggaagctg tgatgtcctt cattcctcat ccattccttt attattcagc 71040
acgtttattc cttgtcttca gtgtgcctgg cagaatgatc gtggggacac gtggagcctc 71100
actgccccga aggagacgca gggtgcttgg gaagagaaca tggagatgtg ggttcttttg 71160
tcaacagcac acaggagcca gccccaggag ttcctagtgg tcagtgctga aaaagaagat 71220
acattttgca gcaaaataca tacatagctg agtctgtgtg cttcaataac taagtggagg 71280
agaatagaca gatctgagca aaaaattctg aatttatgta gctgctctgc cctcagagag 71340
gtggaatata atcccccttc cttcattgtg gactgcgcac agtgacttcc ttccagacag 71400
tgccaagtgg aaaggggagg agagagtggc tttacagtgg aaaccctgac aggtagctct 71460
cgacacggtg ttcggggtca ccatcagcag tggcaaatca ggttgatggt atataccttg 71520
atgtgtgacg agaagggtgc tttacctcta tgttcttcct ctgcaaacac cgtaatccca 71580
gtctgaccac gagaagaaca tcagacaaat ctgtgaggag tggtctacac agtcctgacc 71640
agcactcctc acgactgtca aggtcatcag aaaaagagag tccaagaaac tgtcccagcc 71700
aagagaagcc tcacaagaca ggacagctgg atataacatg gtatcttgga tgggatctca 71760
ggagagagaa aggacatggg gacaagctga ggaaatctgg tttccttact ttgccttggt 71820
gatagtttct cagacttgcc ttgttctcga tgagcttgac agtttcgagg agtgttcctc 71880
aagcgggaat ttgtttctat ctctctagac tagtctcagc ttgtggggtt ttagaaggaa 71940
gactgcagag gtcaggtgtc attcttttca catctgtcag cctcctaaag tatttttttt 72000
aatttctgta aagttcagtc tttgtgctct gaagttcttg gcaccatcag gggttttctt 72060
gtggtttttt gtttttagtc ttttttacag aagtatgaaa catctagttg tggttttctt 72120
ttttgagaac tgtatttctt tctggttgct ctgggtctcc atcactgcga gtgggcttct 72180
ctagttgcct cgagtggagg ctgcttttta ggcgcagtgt gcgggcttct cattgtggtg 72240
acttctcttg tggagcacag gcccgagagt gctcaggttt tggtagtcgt gcctctcggg 72300
ctcaatagtt gaggcgcatg ggcttcattg cctcgcagca tctggaatct tcctggacca 72360
gggtttgaac ccgtgtctcc tgcattagca ggtgaattcc taaccactgg accatcaggg 72420
acgtgcttag ttgtggtttt aaatttgcat ttttcagatg aatattgttg aggtcttgtt 72480
gtatttgcac atcttccttt gtgaagtatt tcagtatttt gctcattttg agctgagttg 72540
tgtggatttt ttttaatatg caaagctatt caaagaagta tattgataat ggaaaaagtg 72600
caataatcta gatatcctta tatagagaaa taactaaatt atactacacc cataaacttg 72660
aatgtaccca ttaaatagat ttttaagctc aacaaagtag attaagtagg aaaagccaaa 72720
gataaaacag tatgtgtact ataccaaccg tttaaaaaat acatgcatag aaaaagtatt 72780
aattgcttaa tcatgtctga ctctggctgg atggcatcac tgactcgatg gacgtgagtc 72840
taggtgaact ccaggagttg gtgatggaca gggaggcctg gcgtgctgca gttcatgggg 72900
tcgcaaagag ttggacatga ctgagcgact gatctgatct gatctgatgg tagttttatt 72960
cgtagttttt aaagagaagt tccatactgt tctccacagt gtctgtatca gtttacattg 73020
ccatcaacag tgcaagaagt ttccctttct ccacatcctc tccagcattt attgtttgta 73080
gatattttga tgatggccta tagtttcctt tgctgtgcag aaacttttaa gtttaattag 73140
atcccattta tttttgtttt tatttccatc attctaggac atgggtcata gaagatcttg 73200
ctatgattta tgtcaaagag tgttctgcct aagttttcct cttaagggtt ttatagtttc 73260
tggtgttaca tttaggtctg taatctgttt tgagtttatc tttgcgtgtg gcattaggaa 73320
gtgttatagt ttcatcctct tacgggtggc tgtccagttt tcccaacacc acttattgaa 73380
gagactgtct tttctccttt gtatattctt gcctcctttg tcaaagataa ggtgcccgta 73440
ggtgtgtggg tgatggattt cttttactga gttataattc tttctgtgtg ctggaggtgt 73500
ctctctgtgt agccctcttc tcccctttta ctaacgtgtt cccacagtgg gatggaggct 73560
gcaccctgcg gttgggcctc gtgcgtgtct gtcctccaga aaggactcta atcaactctg 73620
ccggcatctc gtgccctggg ttaggcctgg cgtgtgttgg agtcactgat cacccccatg 73680
tgggggtgcg gggaggtcag ttcccactgg gaggaggggt gtttttacca gggcaaagca 73740
gaaaggtgaa gacttggcgt ttctcagctg tgtgaccttg ggcaggttat gtaacgactc 73800
tgtaccttag tttccacatt cgtaaaaggg ggataatagt gacacctgca ttacagttgt 73860
cacgggatga cgggaagggg tgcagattca ggtcggcgtc tggcccgccg ctggcatctg 73920
taaatgagtc tggctgtcac cactgtcctt gcttacatct ggccagggtg gagggccggg 73980
cagaggttcc tgtgctcaga ggttctaagt gcgctaggcg tgctctccgt gtctgtcacc 74040
aagagacaga agtgaggctt tcttcttgga gcttgatagg tgatcaggta gttgggacca 74100
agttaaatcc tgggctctgg agtttaaatg aatcccctca gcagtgggaa gctgagccct 74160
tcgaggcagc gacttggtgt gagagtggtg gtaagatggt cagtcttaca gaaacctgga 74220
gatgggggtg atggtgcgta ggaggagggt gagggggcca gagaggggaa gggggcttca 74280
ttttacaggg atcgcaaggc tacctgtaag agctttagga cataatgata cactagatgg 74340
aactggcgtg catcgggcta catgccttac tggctggttg cttgtgttgt gttatttggt 74400
ctgcacagtg atctgccgag ctctgagggt ctgtccccgt ttccctcaat tctgggactg 74460
atgcttggaa agcgtagaga cccttgtcca aggcacgcag ctgggggtgg agctagaatg 74520
tgaagcccag catggcccct gcacctcccc ccacagccat tccccgcctg tccagggctg 74580
gggaacaagg agcaggatcc cgtcctccag gagctgagcg gtgggagtgc tgtcaggggc 74640
ccctgggtgt gtcagcgcaa aggcaaaggg cctggagctc taggatgctt tctctgaaag 74700
agaaggatgg attatgtgtg tgtgtgtgtg tgtgtgtgtg tttaaacaag cttattttat 74760
tttattttat ttatttttgg ctgtgctgta tctttgttgc tgcgctggct tttttctcca 74820
gttgccgtgc gcaggcctct cattgcagtg gcctctcttg ttgcggagca ccctagggct 74880
cccgggctat agagcacagg ctaaacagac atggttcacg ggcttaactg ctccacaaca 74940
cgtgggatct tagaccaggg atcaaacctg tgtccattga tgggcagatt ctttaccact 75000
ggaccaccag ggaggcccag ggattgtgtt taaagcaaca acaagcctga gatgtcctgc 75060
tgtggcctgg ccctgctaga ctggatcatc atggaaacct ggccctcatg ccaggccctg 75120
cctgccggtc cacctgggtg cctgggcttc caggccagcc ctgcagcgtg ggcggtggca 75180
gcctaagcct gaatgcgagg tttccgagga gcccaggtca gggttcgcat gctgagacgg 75240
tggcagctga gaccccacag gccctaggac ctcaactccc ctccggcact gctgtgctgg 75300
gcctttgctt ctgctccctg ttctccatgg gatccacatg gttcagaacc accccggcat 75360
gtaggactca cagattggga actgggcagc cccgggcttg actcctgcct ctgctgcttt 75420
gtggccttgg gcatactctt gttatctctc tgagacttga ttttcttatc tgggtcctct 75480
agctcagggt cccttactgt gaaggctgcg gttgtctcag agcctgcatc cacgtcagac 75540
agtgagggaa gcacgccccc tgcaggctgt gggctggggc ctctggtccc tcactgggta 75600
ttggttgaaa gtcccctcag ttctgtgcct tgtggacctt tttggagcgt ttcacaattc 75660
ggctgacatc accagagtgg tggctgtaag gacggggcta aggaatgttt tttccttcca 75720
tttaaaacaa attgcggcag caaaagcacc aagtcctacc ccttggccca ccagggaatt 75780
ccctctcaac tatttaagcg taccgttcag tggtattaag tgcattcaca ttgtacaacc 75840
attaccacca tccttctcta taatgcttca tctcataaaa cagaaaccct gcaccagtta 75900
aacaataact ctgtactccc ccttctccaa cccctgataa ccatctttct gctttctgac 75960
actctgaatt tgactccttt aggcgcctca tatcagtgga atcaggtggt gtttgccttt 76020
ttgtgcttgg tttatttcac ttagcataat ggccttaaga gtaatagtct tttgtagccc 76080
aatctcagaa ataaagagct catcattttg ctatattctg tttctcagaa gcaagtcacc 76140
aggtccagcc cactcgccag cagaattaca cttgggcatg agcatgagga agtggggctt 76200
actgggggcc acgttagaag cccccatctg tgagggcccc tccctctgat cccagaggca 76260
ccaggactcc actggccctt aggtgctctc catcacccac ttaggatacc ttgtgtcatc 76320
tgtttccgtg ttgtaggctt ccatgtctgt gtcttactcg agtttcaggc ggggattatg 76380
gtaaggccca gcagtgagtg gtaggtcctg cccacctctt ctgctcccat gttcgtgcct 76440
gccagctacc agcatccgca tctcatttgt caaagatctc tggcacggaa ggcctgaggt 76500
gctggagaat tcacatcccc taggagctgc ccttatcctg taactgtagg aggagttggt 76560
gtgtaacctc agccatcatt ctttatgtgg ggtaactcag ctaaaccgtc atccacaagg 76620
gtcacttgct cagcagccca cccttggtgg tggtcttcct tgccctgccc tgtccctgct 76680
cccctccccg tgttcctacc acctcctgag gacaccgtgt atccagggtt tgctgctggg 76740
ggaaccccaa ccgagacagt gagtggaaca gtgaatgaat gacaagagtt aggctcctgc 76800
ctgttagata aaccaccgta agagagttgg gatgcctgga agaggggagt tgagggcaca 76860
tacactggac gatgagtttg atacagacat gctagactga cccaagatcc tgaaagagct 76920
gggtggatgt gggatagctg cttggagagt tcagctggaa gtcgggaggg cgagtgaggg 76980
ccggcctgca gacagagggc caggcgaagc gaacggctgt gcgtgggctg tcctctctgt 77040
ggttttgcct ggtgagcctc acctgctgag gagtgagagc agatgagcag ggggggttta 77100
cccgagcggg tggaaggtca aaggagagag aggcgtgcag ggctgagggg gttcagattc 77160
tgtgcaatct gaaagtcgtg gatcctctcc cctaacaatg atgaggttat gatagtagat 77220
acacttctga gaagaaatgt gagttgggca gggtgctcac agaactcctg gggccatccc 77280
aagagccctg atggagagct ctggttctga agtacgttct ttgttgcttt gctgaaatgg 77340
aggcctggtg gggtctgggt ttggactgga gggccaggga gccgtcctgc ttggaaactg 77400
aagcttcggt tgggccccgg gttgaggggt ggaggaggtg gtctctgcgg tcacagcctc 77460
gtgcccactg tgaacagtct ggtggctcta ccgggccagc tgtccctggg tgccatgctc 77520
tgtccttcgc ggagatgctg gagggtgctc accccagtgt cgctctccct gtggagctgc 77580
gagctgtgtc gagtcgagga gctcaggtgg cgtccgttct gtgcaggtcc ctctgcacct 77640
cctgacatcg tctgccgggc ctggtctgtg cagaaggcta agcgcgtgag gcttctgtcc 77700
ccagcgcctg tcagaaatgc acacttcacc aaggctcagg tggtgcctgg ggtgctttgt 77760
gtgatcagta tcttggccca tgcttaagct ggagcacggt gttgttgctg gtggatggcg 77820
tcctctcctc acacccgccc ttcagagttc ctgatggccg cacaggtgtc gggacatccc 77880
cccatccctg accaggcccg gctccctcca gctggcacct catagcaccc tagggctgca 77940
ggctggcctt tcctgtctcc gggtagatga tggcctaact ttagtgttcc ctggagcact 78000
gctttgtaag gtcgcccttc cctctgagac agtcagggct tttcttcgtc acctggttaa 78060
aacccagaca gttcagtcag gcgtcatccc ggccccctca ttgctctgtg atttccgtta 78120
ctcccatcag gactcccctg tgctgtctga gctgcccctg ccccctcctg ccccccgcct 78180
cctgaccacc cctcccnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 78240
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnccac 78300
ccccccacta cccctcccac ctcgcagccc caacgcagct cctcccggcc aaaaccctgc 78360
ctcggccagt ccagtcttgt tttggggctg ctcctcgaca cgtccaccgc tgggagtcgt 78420
tccttgcctg ttacatgtgt gtcactttgt cacttaagtg cctttaagga tacacagcag 78480
gttctggtga ggggagtgtg gtgtttcagt gagatctggg taggaatcct cacatcctgc 78540
tcaagtcctg agacctggag tcactttgct tctcatagga gagttgtgcc ggccagtgag 78600
aggacacacc acacctgtgc ttgcttatgc gtccatggac acttagtctc tgcgtgcact 78660
gtgtgtgtgt gtgtacacgc gtcctagtga tgctgcagtg tgaatgtcat tatccccatg 78720
tcacacggaa gaaactgaaa tccagagacg tcaaagttat ttccaaggcc acacactttg 78780
aagagcagag atttaaaact gggtctcctg agctcaaaat ccactgacct gcaagtggca 78840
aaaccagggt cagcacaatg ggttctgccc ttggggagct tgtggcctct tggcaggtcc 78900
tcaggcgttt ggcgtcaagg gctggataag acaggtcttg tgcaggcttt gagggtcact 78960
ctgcctgttg tgaactctca cctctcattg ttgtgtgaaa gcagaacagt gtggaatggg 79020
gtggctgtgg ctctgttcca ggaaaacttt ctttagtaaa acaggtgcca gactcactta 79080
atggcctgtg gtcactgttc tgttgagaaa taggtaggaa agtggtttat tcagtggtga 79140
gaaggccctt gtgaacgtct tcattattta aaaaaaaaat tttttttggt cacaccacgc 79200
agcatgtggg atcttagttc cctgaccagg ggtggaaccc acaccccttg cggtggaaga 79260
acagtgtctt tttttttttt tttaatactt attttgcggt accaggtctg aatggtggca 79320
cgcgggatct tccatctttg tgggtatgca ggatctttac ttgtggcatg tgggatccat 79380
ttcctgacca gggatccaac ccgagccccc aactgtggaa gctcagagtc ttaaccactg 79440
ggctgccatg gaagtccctg ggcatcttcg tgtttgaagg gctgtatggc tttgcccatg 79500
ctaggtgctc agtcagtcct tacccaggac cggccgtgtt tctccctctt gtgctgagct 79560
accttgctgg tggtggttta gttactcagt cgtgtctgac tctttgcaac cccatggact 79620
gtagcccgcc tagctcctct gtccatggga ctttcccagc atgagtactg acctttctac 79680
catcccccat ctcttccgca gtacgtgggg gccccggtgg cttatatcca gcagatattt 79740
gtgaaatctt ccgtgtctcc ctggcacaag aacctcctag cagtagatgt gttccgctca 79800
cctctgtcga gggcattcca gctggtggag gagattcgga accacgtgct gaaagacagg 79860
tatccatgcc aggccccagc ctccccgacc cagctccaca cctaaggtgg ggcacagccc 79920
tcagcataaa tctgccgagc tggccagctc tgcgagacta agagggtggg tgagctcgct 79980
tcgcctttct caggggcgaa agtccacaca gctgctgggt ccactgcagc tgtgttcccc 80040
tcagacctgt gcccacagcc cagggagagc cctgagcttc gtccccaggc ctcacacaga 80100
tggatccact gggccgactc tgggacaggc tctccgagac ctggttgact ggtggccctg 80160
agggctcact gtccagagct tgtgagatgc gagtgtgatg gtggccaagc tgacgagaag 80220
ccagctgtgc ccagaggtcc cctcccggag tcccagccca ccagtgcttc tctggggcgt 80280
gctaccctgc aggctgcctc agtgctagtt gaggttagct gagggcttgg gccacacaca 80340
gcacctggtt ttcaccctgc ctcctctgcc tgccgaactg caggggttct agtgagggag 80400
ctgtgctcac tcccgagcac gcctctcctc agaggggctg ggctttgggg ctccacgtgc 80460
acttggaagg tcaggctgcc tccccgtgtg gtggctgagc ccctggaaga acttccccgg 80520
ctgcccttgt cctcggccct ttgagacacc aggcacctgg gagcgtcatg cgcggggctg 80580
tgtagggctg gcagactcgg cagcgcctcg tcctgtcccc cgcacagctc cgggaccagg 80640
agcctggagg acgtgtgcct gcaggtgact gacctgctgc caggcctcag gaagctccgc 80700
aacctcctgc ccgagcatgg atgcctgctg ctgtcccccg ggaacttctg gcagaatgac 80760
agggagcgct tccacgcaga ccccgacatc atcaggacca tccaccagca cgagcccaaa 80820
accctgcaga cctcagccac actcaaaggt gccggggcag tcccttgaga gccatcgggg 80880
gcctgtcagt caccacatcc tcttcagagg ctgctctggc agatctgggg ttaccctgag 80940
tttctcaggg tggggaagaa aggggtcctt ggtatctcta tgtagctgcc ggtcctttgt 81000
cagcacctgt tgccctctgt ctgcagacct gctgttcggc gtccctggga agtacagcgg 81060
ggtgagcctg tacaccagga agcggctggt ctcatacact atcaccctgg tcttccagca 81120
ctaccatgcc aagtaaggcc gggctgcggc acagcaggca ccttttccgt ttggagtgtc 81180
cacagtgccc ccgggagctt ggagttctca ggccttctgc tgaaatgttc atgtccctca 81240
gggtgctgtc tgctcacgct tgaggggggc cacctgacag ctggctaaga acaatgggga 81300
aagcaggcct ggcaagctca gggtcccggt gcctccatgg tctctctgga gcctcggatg 81360
ggggtcccta gctggtgact gccaagcccc atgtgacttg ggagagcaca gcagagagtt 81420
ctccgagggg cgagggcatg gagggggccc ccgatgggct gttctgggcc tgtggcagtc 81480
agagcgcagt gataggttgg gagtggggtc ctcaggggcg ttctgagaca gctgggccaa 81540
ccccctcaag actggaggga aggttagaca ccgcgaggag ggaatcccca gctgaccttc 81600
cttcagggat tgcctttgtt ccccggacag agagggacag gccatctccc accccccacc 81660
caggttcctg ggcagcctgc gggcccgcct gatgctcctg caccccagcc ccaactgcag 81720
cctcagggca gagagcctgg tccatgtgca cttcaaggag gagattggca tcgccgagct 81780
catccccctg gtgaccacct acatcatcct gtttgcctac atctacttct ccacacgtag 81840
gtccacagca cagaggccag ggctttctcc cagctaatct gggcgtttcc agatcactcc 81900
ttccctgcct cttcaggggc ccaggcagag atgtagaatg tgccagctgg tcactgaagc 81960
tggggcttca tcccccagcg ggggatgggt acgtccaggg ttcctcccac tactcacaag 82020
tcccttcctg ggaaggtttc caaggacacc gtgccccgag actgggaagg gtacacgttc 82080
tctgcgcaaa ccagggcctt ctcttcctcg accgtcaggc acaccccctc ccagctctca 82140
ggatacaggg cccagtgagc caggctctgg ggagaggctg ccctgatgtg ttctttgccc 82200
tccaggcaag atcgacatgg tcaagtccaa gtggggcctg gctctggctg ctgtcgtcac 82260
ggtgctcagc tcgctgctca tgtctgtggg gctctgcaca ctcttcggcc tgacacccac 82320
cctcaatggc gggtaggtcc cagcaggctc ccctgggggg cagggtgggc ccgcaggccg 82380
gagcatcatg cacctctggg tgcttggcct gccctgccct ggacacttgt tgttacccca 82440
tattttcaca tgataatttt gacacttaag aggtatgtgt tttttcttct tgagttacct 82500
ggcttacgat catacatatt tatatacaaa ccatatgtat atttacgtat aatacatcca 82560
taggtgtgtg tatgtatgtg tatattcatg tgtatatttg tgtgtgtata tggggtaagt 82620
atttatatgt gtgtatgtat gtgtttacgc atatgtgtgg gtatgtattg tgtgcgtctg 82680
tgtgtctgag ggtgtataga tgtgtgaatt gttgttgttc agttgccgag ttgtgtctgc 82740
gaccccatgg attgcagcac gccgggtttc cctgtccttc actgtctccc agagtttgct 82800
caaactcgtg tgcattgagt cggtgatgcc atccaaccat gtatttatat attttaaata 82860
catgtgcaca ttgcttctca acagcttaag ccgtagatga gtgtgacata gagacggtac 82920
gtttcttcct ttcttaatat taaaacattt aaattgcttg gtaggtccct ttggagtaag 82980
cattttaaaa gatacaggcc ataagcacac tctgatttgt caccttccca ccgtttgctt 83040
cccttccatt tctctcagaa acatggtcct gccctggacc ccaccagcct gttagtgatc 83100
acagccgact ggcctgtgcc ctgcctcggc ttgtcaggct gctcccagga acagtgatct 83160
tgtgtttcct cttccttccc ttgcttgtag aacatttgct tcctttccta gacctgatgg 83220
tgctaatcac ccctcaagga tagctgtctg ctctgcctcc tcagagcccc ccacaccgcc 83280
ccctagcgga gatcccagcg ccgtgctcga ctggtgttcc ctagtcaggg agcggggagc 83340
ctgtggtctg agagagctgg gggagttttc tttagaaacg attgcccttc tccacgtgca 83400
gcttctcttc agaggcgagt agggcttcag gctggcctca tccccttcca tttagtcctg 83460
atggcctggc ctggcgtgct gcggtagggg ctcctctggc tgatggtgtg gtgtggaaag 83520
ggccagggag ctgtgctctg gcagctgggc agtgggggcc tcttcccacg gtgctagaca 83580
gatggagagc aggatggtgg ctggctcctc ggcacgactt ggaagccggc ctgaaagctg 83640
cgagccatgt agacagaggc ctcctggagg gtggggttcc agtcctgtga tgtgggagtt 83700
gcttggcagc ccccactgtg ggccagaccc cacagggccc caggagccag gcctgctgag 83760
gagcagctgt gtgttggggg ccccctcagc accctcctcc cccaaccctg ctctgtcccc 83820
agggagatct tcccctacct ggtggtggtc atcgggctgg agaacgtgct ggtgctcacc 83880
aagtccgttg tctccacccc ggtggacctc gaggtgaagc tgcgcattgc ccaaggtaac 83940
agtagggagt gggaggcatg gcggcggggg ttgtgctgca cctcctcctg ccgagggaac 84000
ggggagccca ggagcctccc tcgcccggcc tccactaaca cgcccacttg ttagcgtgag 84060
ccctgtgcag ccatggagcc cagggtcctg ttttgtccag gtccacatgt cagtaagacc 84120
acaaaccgcc tctgctgcgg gctcacgtgt ttggcccttt ctccggttgg cagctggtct 84180
tttctcttcc tgccccactc tatcatgtga ggcccagact cctggagccg gtcagctcag 84240
agacgctgcc tccacagctg ccaggaaaga cctgtgtggc cttagtggca ggagctgggg 84300
agctgggttc tgaggaaagt ggggaaagag cctgggcctg gaggtctgaa ctctcacatc 84360
tcctcttcct cttccacctc agcccgtatc tgtgggaaca gggccggggc aggctgttcc 84420
ttcactcagc aaagctttgt gaacctatgt gagaggccag gccctgcact agacatgggg 84480
ttccaaggag accaggggaa atggctgcta cccactaggc gctcagagct ttaaatgtgc 84540
aactgtgtgg tggcccgggg cccgggaggg gctggcgtag gacacagccg gctctcctgt 84600
ccctcgagcc ctctgccacg tgcgaggctg gacatgccgg tctgggtgga tgtggctctc 84660
ctgggtctgc tcaagtcagc gacccgcttc tcccttcctc agatggtcgg agctctcctc 84720
cggaccttca ggcccccctt ccctgtaaag ctgtgcccat agcagggtcc ttagggttgg 84780
ggcatttggt gggcagctgt cttgtgggcc atgcagtcat tggcccacat gcagtggaca 84840
gaggttattt gttgccctat ggccccgttg tcccctgcag gcctgagcag cgagagctgg 84900
tccatcatga agaacatggc cacagagctg ggcatcgtcc tcattggcta cttcaccctc 84960
gtgcctgcca tccaggtgag gcctccgggt ctgtagcttg ggccgtgtgg agcccattac 85020
tgagcctccc agctgtgcag ggcacaccct gccttgctgc tgccctctcc tgtgaggtgg 85080
cccctctgct ggcaggctgg ctgtcactgt gcacagagag gtcctggtgg aactggccca 85140
ggaggaggac tcagtaagcc gagctacagc ctggcagtct cagacccatg acccctcacc 85200
catgaccgct cactgctgtc cctcactcaa gtggcaggag gggaagctgg ctgcccgcag 85260
cacagtccag tcaggccccg tttcccagtt ctcaggcaga aagtggtgag gcccccctgc 85320
ctttcagggc ctgagccctg acccgccccc gcacccttga gacccatggc cccaccctgg 85380
gagagccacc agccattgct gagccgtggg gctgcgagca ggaagcccac tgttgctgcc 85440
tgggagtttt gtgaagggag taaggagtcg ttgcctcctg tcctttcctc acgactggca 85500
ggcctgctga ggtttgggaa ggaagccagg gcccccaggc tccccaccct acccctctag 85560
agggcgtctg caggacacgg acggtcttgg gacatgaggg ctgacgtgcc actgtgcact 85620
ccattcttca ttttcctcac atttgagtag aagccatggt gatgcaccag aggtctcaac 85680
aagggcggag gaggaaaact taaacccaag aaaactccat ctatccacag agcctgggga 85740
gtaaagagat tccccttttc agtttctggg tagaattaat tctcccctgt gctcttcctc 85800
tcctttcatt ggtccagtgt agtcactggc caggaataag aaatttctga gagcctccaa 85860
accaggccag gcctgggctc ttggtaggtg ttggtccctg gtacatgagc agggctgggg 85920
cctcagttag ggagggcttt tggagtactg caggctgctg gggcatcagt gccaggggtc 85980
tctgctgccc cctcgtgggg agggagggag ctgctgctgc atcctccttg gcggctcccg 86040
gatgtcaaag ttccagcatc tctcctcccc gctgtgcctg gcaagaaact gccctgcagc 86100
atccagggtg ccagctgttg ggggtgcagt ggtcagggcc catggccgtg gtccagaggc 86160
tcccacatgg ggctgcggcc gcagcaggca gggaactggt tctccagtgc tgggccctga 86220
ggtcagtgtc ctctcattgc cttttttcca ggagttctgt ctttttgccg tcgtggggct 86280
ggtgtctgac tttttccttc agatgctgtt tttcaccact gtcctgtcca ttgacattcg 86340
ccggatggag gtaggagtga gctgaaccct gccctaacca cctccgcctc agccctggct 86400
gtgctcaggg gtctctggac aagagagggc agacctgggg caggactgca gccccacgtg 86460
ggagcttgtg gaccgcggct ccaggccctg accactgcac ccccaacagc tggcggacct 86520
gaacaagcgg ctgccccctg aggcctgcct gcccccagcc aagccagtgg ggcggccaac 86580
acgctttgag cggcagccga ctgtgcggcc gtccatgccc cacaccatca cgctgcagcc 86640
gtcctccttc cgcaacctgc gtctccccaa gcggctgcgt gtcatctact tcctggcccg 86700
aacccgcctg gcacagcgcc tcatcatggt acctgccacc cccacccgca ggcccgcact 86760
cacagtcctc ttgccgtttg catttgtctt ggggggggtg ctccccaggc cctcgtggcc 86820
cctggaagcc tgactttggg aagcctccct ttctcccctc ttgcccagac cttgtggttt 86880
ctggggtgag aagcctgtct ctggagaagc agctggtgtc atcagggaga ggagtctgcc 86940
cagagtgacc aggacgggtg ctcttggatg gaaccaggtg gttccccaag tcagggttca 87000
ctgtgcaggc agcaggaaat gctggctggg cagagggaag gaggagcaag gttggctgaa 87060
gtgagagggg agcggggctg aggccctctg aggactgaga cccgtggtgt ccctggagca 87120
ggtcaggcag ctggtccctg cggctatgct gaccatgggg gcccaagttg agggagcggt 87180
tagggtggga aagttctgta tcgaacccgg ggtgcctctc tctgtttcgg ccaggagtct 87240
caaacccgag catggaaagg gagcttggtc cgtccagggg ggcagttggt cttagtcata 87300
gaggacttga ggcagaaggg aaggacaggt ggcctgtgtc ctctctctac cccctggcct 87360
gccgctttcc agcgtgaggg ccacatgtgc agcgggtgag ggctgcccct tcctccctgg 87420
ggtcctgctg agcccccact ccctgctgca ggccggcacg gtggtctgga tcggcatcct 87480
tgtgtacacg gacccagctg ggctgcgcac ctacctggcc gcccaggtaa cggagcagag 87540
cccgctgggc gagggcgccc tggctcctct gcctgtgccc agtggcgtgc tgcctgccag 87600
ccacccggat cctgcctttt ctatcttccc gccggacgcc tccaagttac ccgagaacca 87660
gacgttgcca ggggagctgc ctgagcccgg gggtctggcc gagggtgtcc atgacagccc 87720
ggccccagag gtcacctggg ggcccgagga cgaggagctc tggaggaaac tgtccttccg 87780
ccactggccc acgctcttca gctattacaa catcacactg gccaagaggt gggcggcctg 87840
agctgggtcc cccctcccac ctggtcatgt cagctcactg ccccagagca ccccttccct 87900
caggagggag acccgtgggt ttgaattctg aattttcttt caaataaaca cctatcaggt 87960
tgtggggtgg gaagcagtgc tcccagtagc cacaacctga gtccctgggc cccgctctgt 88020
gaggtcatag gtcgctgtca gctacttagc caaaatgaga tccacacctc acttccccca 88080
ctctgccagg attggtgaca gagggacagt gattgctagg gtggtggcgt ctgtgacggg 88140
gcaaggttgg ggtgccagag ctggaggtgg ggagcctact gctgggaaga ctgtcttggg 88200
agggtgttct tggagcttgg cagagcaggt cgagtcgcat ggggagagta gagggggccc 88260
tgggcagcag caggccctcc gagggcgtct ccgctgaggc tgagcgctgc ccggcccagg 88320
tacgtcagcc tgctgcctgt catccccgtc acgctccgcc tgaacccgcg ggaggctctg 88380
gagggccggc accctcagga cggccgcagc gcctggcccc cgccccggcc cgggcagggt 88440
gggctctggg aggccggccc caagggatca ggcacggcgc aggcgcacag agacctcacc 88500
ctgtacaagt aaggcccacg agtcgggggt ggggcggccg gcggggtcgt ggggccgagg 88560
caggtctcac caggctctgc ccgatgcagg gtggcggcgc ttggcctggc gtcaggcatc 88620
gtgcttgtgc tgctgctgct ctgcctgtac cgtgtgctct gccctcgcaa ctacgggcag 88680
cccggcgcgg ggcccggccg gcggcggcgg ggggagctgc cctgcgacga ctatggctac 88740
gcgccccccg agacggagat tgtgcccctg gtgctgcgcg ggcacctcat ggtgagtgtg 88800
gacggggccg ggggcgcggg gaaccgagcc acgccgcagc cagtgcccat gtgcatgccg 88860
cgctcccgca ggacatcgag tgtctggcca gcgacgggat gctactggtg agctgttgct 88920
tggcaggcca cgtgtgtgta tgggacgcgc agaccggaga ctgcctcacc cgcatcccgc 88980
atccggggta ggtgctccgc cctgccctgt cccgccctag cccctcctcc caggccccgc 89040
cctctccctc atccagtctc cccgccccta gcaggcagcg gcgggacagc ggtgttggta 89100
gcgggctgga gactcaggag acctgggaac ggctgtcgga cggcgggaag ggtggcccgg 89160
aggagcctgg ggacagccct ccgctgcggc accggccccg gggccctcca ccccctgccc 89220
tctttgggga ccagccagac ctcacctgct tgattgacac caacttttca gcgcggccac 89280
agctccccga gccggctcag cccgagcccc ggtaccgggc gggccgccgt gctcaagact 89340
ccacaggcta cgacttcagc cgtctggtgc agcgcgtgta ccaggagggg ggcatggctc 89400
ccgtgcacac gccagccctg cgcccaccct ctcccgggcc cacgttcccc ccggcccctg 89460
aggacgaggc tggctttcct cccgagaaga gctgcccgtc cctcgcctgg gcccccagcg 89520
cagacggctc catctggagt ctggagttgc agggcagcct catcgtggtg gggcggagca 89580
gtggccggct ggaggtgggc agcgggggct ggagggaggc aggggggtcg tgggtgttcc 89640
cagttacagg tgctcacagc ctctgggccc ccaggtgtgg gacgccatcg agggcaccct 89700
gcgctgcagc agtgaggacg tgtcatcagg catcacggcc ctcgtcttcc tggacaaaag 89760
gtgggagcgc taggaggccc gcctcacccc tagacgccca gctccgcaca cactgaggtt 89820
gagccctgct cccccttccc tggtgtgaca acccacacct gtgagctgca ggaagtctgc 89880
cttgatggga ggtgacaact caagagggta aaggtggggc atgaaagaag gcccttcacc 89940
actgacagtg tggagtgcag tcttcctctc accctttgag gtcagacttg tctaggtagc 90000
catcactact gacccttctg ggttttcagt tccagaaaaa cgcatcttga gaactactgc 90060
cttgtgaaaa ctcaccttcc cctttgatgc tgtagactct tcttgcctgc ctcttcacca 90120
tgccttttgg ctgggtgttc ccagcacgcc atcacaccat cacctccgtg gtggggggtg 90180
ggggtggggg gaggtcccag ctactcagac tgggcccctg cacctctggg ctgatagacc 90240
cagggttcac ccacccaagt gcctctggtg accgcctcag ctgcccgtca tgctggctgg 90300
ctcttccttc caggtccctg agcgtgtgtg gcccagcatc tgagctagag cggagccttg 90360
ttttctgcca tggggacacc cctcgccctg acctgtcagt tcctggtggc tttctgctca 90420
ggcctcagct gacatcctac tgtgtagcct ggccaagttc actgggttcc cccgagcttg 90480
gaattctccc ccactggtgg ttttttgaca ttttagggaa agcccacgtg cctcagccta 90540
gctctgcgtc catggctctg ccctgttctt cctctgcccc aactctgctg tggaccattc 90600
agctttatgg gctgaaaatt tgtgaacccc actcgcccca aggctttggg gccacagagc 90660
acacacatct tcatctctgc ccatcagcct gtgcctagga atgccaggca gtggagagaa 90720
tccttatttc tttgtggaaa tgaaacggag caggcagtgc ctgtgttgga gctgcctttc 90780
tgtcgtaggg cagcagtgcc ttctgcgggt cctcacagcc ctgcctcagc tcctgtctcc 90840
tccactgaag cctctcctat ggctccaggc tgtggagggg gactcccctt ccccagactt 90900
ttaaaattcc agtcttactc atgatgttcc ccaggtacca ctttatacta tcatcagctc 90960
atttactctt cacgaccacc tgcccccaca aggcacacag gggataggtt cccattttca 91020
cacatgaagt atctgaggca cagagggtgg cactggggtt gcagggccct tctgctctgc 91080
acctggtccc agcacctgtg cttctatctg ggctgaggtc cctcgcggcc tcactgctcc 91140
ccggccagtg ggacaggcct gtcaaggccc gtggcgctca gccccacggc caggggctct 91200
aagggaaagt cccctggcag ccgctcttgt ctttcaggat cgtggctgcc cggctcaacg 91260
gctccctcga tttcttctcc ttggagaccc acactgccct cagccccctg cagttccgag 91320
gtgggcggcc tgggcaggcc aggggcctca cctagtgggt ggagcgcggg ggccgctgca 91380
ggtgtcttct ccgaggcccc tcacctggcc tgttgtcccc aggggccccg gggcggggca 91440
gttcccccgc ctcccccatg tgcagcagca gtgacagggt ggcttgccac ctgacccaca 91500
ccgtgccctg tgcacaccag aagcccatca cagccctgaa ggcagctgcc gggcgcctcg 91560
tgactggcag ccaggaccac acactgagag taagtgtcgg caccatctct tgggcacgcg 91620
gtggcccagc ataggggtgg ggaggcatct ggggtcagtc agagagaggc tggaggtgtc 91680
ttggatgaac tgtggaaggg aattcctgac cgaagtgtga tttggaaaaa cccacagaag 91740
tcagaggaaa atgaaaatca cataatcaca cgtatttgtg gaatccagaa aaatagtact 91800
gctaagccca tttgcaggga aggaatagag acgcagacat agaggacaga actgtggaca 91860
caccggggaa ggaggtgggg tgagctggga gagtggcact ggcatccagc gccgtgtgtg 91920
gagcagctag tcggggggag ctgctgtgcg acacggtgcg cagccgcgca ctctggagac 91980
cacgaggggc ggggtggaca gcaggaggtg tgggggacac aaaggagggg acacgtgggt 92040
actcacagct gatttcacac acagcagaga ccagcacagt attgtaaagc agttcttctc 92100
taattaaaat aaaaccccaa ggagcccagc acctgaggcc tgtttctgcc acaggtgttc 92160
cgtctggagg attcgtgctg cctcttcacc ctgcagggcc actcgggggc catcacaacc 92220
gtgtatattg accaggtgag ggccgtgggt gggctgtggg agcattgagc cagacccacc 92280
acggccttgt ttctgagtcc tgggagctgg tccccagggc ctccgagagg caggcaaagg 92340
ctccctccca cctgggcact gggacacctt ggggacagag gtggcaccac agtgaccagg 92400
cccccacacc cgctcctgca gaccatggtg ctggccagcg gaggccaaga cggggccatc 92460
tgcctgtggg atgtgctgac cggcagccgg gtcagccata tgttcgctca ccgtggggat 92520
gtcacctccc tcacctgcac cgccttgtgc gtcatcagca gtggcctgga cgacctcatc 92580
agcatctggg accgcagcac gggcatcaag ctctactcca tccagcaggt aggcgtgggg 92640
gccacggggc ctctggttgt cgggaagggc tccagaccct gagcctgtcc tgtccttgtc 92700
tccaggacct gggctgtggt gcaagcctgg gtgtcatctc agacaacctg ctggtgaccg 92760
gcggccaggg ctgtgtttcc ttctgggacc tgaactacgg ggacctgtta cagacagtct 92820
acctgggcaa gaacagcgag gcccagccgg cccgccagat cctggtgctg gacaacgctg 92880
ccattgtctg caactttggc agcgagctca gcctggtgta cgtgccctct gtgctggaga 92940
agctggactg agggtgggcc tctgcgcccc tctggctggg gagctcggtt ggcaatgcac 93000
tggacccgga ttggggagag tgctgagtct tggggaagct gcttcttact gtcctgtcct 93060
gcctcatgac tgtaatatta aatctgtttt tttaaatgac atca 93104
<210> 2
<211> 25
<212> DNA
<213> 人工合成
<400> 2
tcctgattgg gtctccacat ccccg 25
<210> 3
<211> 25
<212> DNA
<213> 人工合成
<400> 3
taaacattag atgtgcaatg aatct 25
<210> 4
<211> 25
<212> DNA
<213> 人工合成
<400> 4
tcctgattgg gtctccacat ccccg 25
<210> 5
<211> 25
<212> DNA
<213> 人工合成
<400> 5
taaacattag atgtgcaatg aatct 25
<210> 6
<211> 22
<212> DNA
<213> 人工合成
<400> 6
ggcaggggtt ctacgtggag tg 22
<210> 7
<211> 23
<212> DNA
<213> 人工合成
<400> 7
ccaatgcagg ggacgcagtt tcg 23
<210> 8
<211> 22
<212> DNA
<213> 人工合成
<400> 8
ttgtgaaatc ttccgtgtct cc 22
<210> 9
<211> 20
<212> DNA
<213> 人工合成
<400> 9
ggatggtcct gatgatgtcg 20
<210> 10
<211> 25
<212> DNA
<213> 人工合成
<400> 10
agcagggtcc ttagggttgg agcat 25
<210> 11
<211>
<212> DNA
<213> 人工合成
<400> 11
ccgcttgggg agacgcaggt tgc 23
<210> 12
<211> 25
<212> DNA
<213> 人工合成
<400> 12
agcagggtcc ttagggttgg agcat 25
<210> 13
<211> 23
<212> DNA
<213> 人工合成
<400> 13
ccgcttgggg agacgcaggt tgc 23
<210> 14
<211> 19
<212> DNA
<213> 人工合成
<400> 14
cctgtccatt gacattcgc 19
<210> 15
<211> 23
<212> DNA
<213> 人工合成
<400> 15
ccagtgtgat gttgtaatag ctg 23
<210> 16
<211> 20
<212> DNA
<213> 人工合成
<400> 16
ggacgcctcc aagttacccg 20
<210> 17
<211> 18
<212> DNA
<213> 人工合成
<400> 17
gccgtccgac agccgttc 18
<210> 18
<211> 20
<212> DNA
<213> 人工合成
<400> 18
gtgttccgtc tggaggattc 20
<210> 19
<211> 21
<212> DNA
<213> 人工合成
<400> 19
gacagtcaga agcagctttc c 21
Claims (2)
1.一种选育奶水牛品种的方法，其特征在于：所述奶水牛的选育包括奶中的总干物质含量高的奶水牛、奶中的无脂固形物高的奶水牛和奶中的乳糖率高的奶水牛；
应用SCAP基因SEQ ID NO:1中的G1743088A-GA TGTAACCCGCG/AGGAACTCTGG、G1760740A-GA GTTCTGTATCG/AAACCCGGG、A1762368G-GA AACCGAGCCA/GCGCCGCAGCC、T1766036C-CT GGGTCAGCCAC/TATGTTCGCTC的基因型进行判定和选育奶水牛产的奶中的总干物质含量高的奶水牛；
应用SCAP基因SEQ ID NO:1中的A1762368G-GA AACCGAGCCA/GCGCCGCAGCC奶水牛产的奶中的无脂固形物高的奶水牛；
应用SCAP基因SEQ ID NO:1中的A1717600G-AA TTTACACAGTA/GGAACTTGAGG、G1718168A-AA TGTGTTCCTGA/GGGAGCCTCC、G1743088A-AA TGTAACCCGCG/AGGAACTCTGG、T1753656C-TT CTGGGCCGACC/TCTGGGACAGG、G1759116A-GG TGCAGGACACA/GGACGGTCTTG、C1759142T-CC TGAGGGCTGAC/TGTGCCACTGT、G1760740A-GG GTTCTGTATCG/AAACCCGGG、A1762368G-AA AACCGAGCCA/GCGCCGCAGCC、T1766036C-TT GGGTCAGCCAC/TATGTTCGCTC奶水牛产的奶中的乳糖率高的奶水牛。
2.根据权利要求1所述的方法，其特征在于：
(ⅰ)获得A1717600G位点的引物序列为：
正向引物SEQ NO:2：5’-TCCTGATTGGGTCTCCACATCCCCG-3’；
反向引物SEQ NO:3：5’-TAAACATTAGATGTGCAATGAATCT-3’；
(ii)获得G1718168A位点的引物序列为：
正向引物SEQ NO:4：5’-TCCTGATTGGGTCTCCACATCCCCG-3’；
反向引物SEQ NO:5：5’-TAAACATTAGATGTGCAATGAATCT-3’；
(iii)获得G1743088A位点的引物序列为：
正向引物SEQ NO:6：5’-GGCAGGGGTTCTACGTGGAGTG-3’；
反向引物SEQ NO:7：5’-CCAATGCAGGGGACGCAGTTTCG-3’；
(iv)获得T1753656C位点的引物序列为：
正向引物SEQ NO:8：5’-TTGTGAAATCTTCCGTGTCTCC-3’；
反向引物SEQ NO:9：5’-GGATGGTCCTGATGATGTCG-3’；
(v)获得G1759116A位点的引物序列为：
正向引物SEQ NO:10：5’-AGCAGGGTCCTTAGGGTTGGAGCAT-3’；
反向引物SEQ NO:11：5’-CCGCTTGGGGAGACGCAGGTTGC-3’；
(vi)获得AC1759142T位点的引物序列为：
正向引物SEQ NO:12：5’-AGCAGGGTCCTTAGGGTTGGAGCAT-3’；
反向引物SEQ NO:13：5’-CCGCTTGGGGAGACGCAGGTTGC-3’；
(vii)获得G1760740A位点的引物序列为：
正向引物SEQ NO:14：5’-CCTGTCCATTGACATTCGC-3’；
反向引物SEQ NO:15：5’-CCAGTGTGATGTTGTAATAGCTG-3’；
(viii)获得A1762368G位点的引物序列为：
正向引物SEQ NO:16：5’-GGACGCCTCCAAGTTACCCG-3’；
反向引物SEQ NO:17：5’-GCCGTCCGACAGCCGTTC-3’；
(ix)获得T1766036C位点的引物序列为：
正向引物SEQ NO:18：5’-GTGTTCCGTCTGGAGGATTC-3’；
反向引物SEQ NO:19：5’-GACAGTCAGAAGCAGCTTTCC-3’。
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